Activity type | Activity value | Assay description | Source | Reference |
---|---|---|---|---|
MIC (functional) | = 0.06 ug ml-1 | In vitro minimum inhibitory concentration against Streptococcus pneumoniae CL2883. | ChEMBL. | No reference |
MIC (functional) | = 0.13 ug ml-1 | In vitro minimum inhibitory concentration against Escherichia coli MB2884. | ChEMBL. | No reference |
MIC (functional) | = 0.13 ug ml-1 | In vitro minimum inhibitory concentration against Klebsiella pneumoniae MB4005. | ChEMBL. | No reference |
MIC (functional) | = 0.13 ug ml-1 | In vitro minimum inhibitory concentration against Escherichia coli MB2884. | ChEMBL. | No reference |
MIC (functional) | = 0.25 ug ml-1 | In vitro minimum inhibitory concentration against Haemophilus influenzae MB5363. | ChEMBL. | No reference |
MIC (functional) | = 1 ug ml-1 | In vitro minimum inhibitory concentration against Staphylococcus aureus MB2865. | ChEMBL. | No reference |
MIC (functional) | = 2 ug ml-1 | In vitro minimum inhibitory concentration against Enterococcus faecalis MB5407. | ChEMBL. | No reference |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.