Detailed information for compound 376691

Basic information

Technical information
  • TDR Targets ID: 376691
  • Name: [(2R,3R,5R,7S,8S,9R)-2-[(1S,3S,4S,5R,6R,7E,9E ,11E,13Z)-14-cyano-3,5-dihydroxy-1-methoxy-4, 6,8,9,13-pentamethyltetradeca-7,9,11,13-tetra enyl]-7-[(E)-3-[2-[(2S)-4-[[(2S,3S,4S)-4-(dim ethylamino)-2,3-dihydroxy-5-methoxypentanoyl] amino]butan-2-yl]-1,3-oxazol-4-yl]prop-2-enyl ]-9-hydroxy-4,4,8-trimethyl-1,6-dioxaspiro[4. 5]decan-3-yl] dihydrogen phosphate
  • MW: 1009.17 | Formula: C50H81N4O15P
  • H donors: 8 H acceptors: 11 LogP: 1.83 Rotable bonds: 27
    Rule of 5 violations (Lipinski): 4
  • SMILES: COC[C@@H]([C@@H]([C@@H](C(=O)NCC[C@@H](c1occ(n1)/C=C/C[C@@H]1O[C@]2(C[C@H]([C@@H]1C)O)O[C@@H]([C@@H](C2(C)C)OP(=O)(O)O)[C@H](C[C@@H]([C@@H]([C@@H]([C@@H](/C=C(/C(=C/C=C/C(=C\C#N)/C)/C)\C)C)O)C)O)OC)C)O)O)N(C)C
  • InChi: 1S/C50H81N4O15P/c1-29(20-22-51)16-14-17-30(2)32(4)24-33(5)42(57)35(7)38(55)25-41(65-13)45-46(69-70(61,62)63)49(8,9)50(68-45)26-39(56)34(6)40(67-50)19-15-18-36-27-66-48(53-36)31(3)21-23-52-47(60)44(59)43(58)37(28-64-12)54(10)11/h14-18,20,24,27,31,33-35,37-46,55-59H,19,21,23,25-26,28H2,1-13H3,(H,52,60)(H2,61,62,63)/b16-14+,18-15+,29-20-,30-17+,32-24+/t31-,33+,34-,35-,37-,38-,39+,40-,41-,42+,43-,44-,45+,46-,50+/m0/s1
  • InChiKey: FKAWLXNLHHIHLA-YCBIHMBMSA-N  


Substructure search Similarity search

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Synonyms

  • [(2R,3R,5R,7S,8S,9R)-2-[(1S,3S,4S,5R,6R,7E,9E,11E,13Z)-14-cyano-3,5-dihydroxy-1-methoxy-4,6,8,9,13-pentamethyl-tetradeca-7,9,11,13-tetraenyl]-7-[(E)-3-[2-[(1S)-3-[[(2S,3S,4S)-4-(dimethylamino)-2,3-dihydroxy-5-methoxy-pentanoyl]amino]-1-methyl-propyl]oxazol-4-yl]allyl]-9-hydroxy-4,4,8-trimethyl-1,6-dioxaspiro[4.5]decan-3-yl] dihydrogen phosphate
  • [(2R,3R,5R,7S,8S,9R)-2-[(1S,3S,4S,5R,6R,7E,9E,11E,13Z)-14-cyano-3,5-dihydroxy-1-methoxy-4,6,8,9,13-pentamethyltetradeca-7,9,11,13-tetraenyl]-7-[(E)-3-[2-[(1S)-3-[[(2S,3S,4S)-4-(dimethylamino)-2,3-dihydroxy-5-methoxy-1-oxopentyl]amino]-1-methylpropyl]-4-oxazolyl]allyl]-9-hydroxy-4,4,8-trimethyl-1,6-dioxaspiro[4.5]decan-3-yl] dihydrogen phosphate
  • [(2R,3R,5R,7S,8S,9R)-2-[(1S,3S,4S,5R,6R,7E,9E,11E,13Z)-14-cyano-3,5-dihydroxy-1-methoxy-4,6,8,9,13-pentamethyl-tetradeca-7,9,11,13-tetraenyl]-7-[(E)-3-[2-[(2S)-4-[[(2S,3S,4S)-4-(dimethylamino)-2,3-dihydroxy-5-methoxy-pentanoyl]amino]butan-2-yl]-1,3-oxazol-4-yl]prop-2-enyl]-9-hydroxy-4,4,8-trimethyl-1,6-dioxaspiro[4.5]decan-3-yl] dihydrogen phosphate
  • calyculin A
  • calyculin B
  • [(2R,3R,5R,7S,8S,9R)-2-[(1S,3S,4S,5R,6R,7E,9E,11E,13Z)-14-cyano-3,5-dihydroxy-1-methoxy-4,6,8,9,13-pentamethyltetradeca-7,9,11,13-tetraenyl]-7-[(E)-3-[2-[(2S)-4-[[(2S,3S,4S)-4-dimethylamino-2,3-dihydroxy-5-methoxypentanoyl]amino]butan-2-yl]-1,3-oxazol-4-yl]prop-2-enyl]-9-hydroxy-4,4,8-trimethyl-1,6-dioxaspiro[4.5]decan-3-yl] dihydrogen phosphate
  • [(2R,3R,5R,7S,8S,9R)-2-[(1S,3S,4S,5R,6R,7E,9E,11E,13Z)-14-cyano-3,5-dihydroxy-1-methoxy-4,6,8,9,13-pentamethyl-tetradeca-7,9,11,13-tetraenyl]-7-[(E)-3-[2-[(1S)-3-[[(2S,3S,4S)-4-dimethylamino-2,3-dihydroxy-5-methoxy-pentanoyl]amino]-1-methyl-propyl]oxazol-4-yl]prop-2-enyl]-9-hydroxy-4,4,8-trimethyl-1,6-dioxaspiro[4.5]decan-3-yl] dihydrogen phosphate
  • [(2R,3R,5R,7S,8S,9R)-2-[(1S,3S,4S,5R,6R,7E,9E,11E,13Z)-14-cyano-3,5-dihydroxy-1-methoxy-4,6,8,9,13-pentamethyltetradeca-7,9,11,13-tetraenyl]-7-[(E)-3-[2-[(1S)-3-[[(2S,3S,4S)-4-dimethylamino-2,3-dihydroxy-5-methoxy-1-oxopentyl]amino]-1-methylpropyl]-4-oxazolyl]prop-2-enyl]-9-hydroxy-4,4,8-trimethyl-1,6-dioxaspiro[4.5]decan-3-yl] dihydrogen phosphate
  • [(2R,3R,5R,7S,8S,9R)-2-[(1S,3S,4S,5R,6R,7E,9E,11E,13Z)-14-cyano-3,5-dihydroxy-1-methoxy-4,6,8,9,13-pentamethyl-tetradeca-7,9,11,13-tetraenyl]-7-[(E)-3-[2-[(2S)-4-[[(2S,3S,4S)-4-dimethylamino-2,3-dihydroxy-5-methoxy-pentanoyl]amino]butan-2-yl]-1,3-oxazol-4-yl]prop-2-enyl]-9-hydroxy-4,4,8-trimethyl-1,6-dioxaspiro[4.5]decan-3-yl] dihydrogen phosphate
  • 21279_FLUKA
  • Calyculin A from Discodermia calyx
  • C5552_SIGMA
  • Calyculin
  • CCRIS 3706
  • L-Ribonamide, N-((3S)-3-(4-((1E)-3-((2R,3R,5R,7S,8S,9R)-2-((1S,3S,4S,5R,6R,7E,9E,11E,13Z)-14-cyano-3,5-dihydroxy-1-methoxy-4,6,8,9,13-pentamethyl-7,9,11,13-tetradecatetraenyl)-9-hydroxy-4,4,8-trimethyl-3-(phosphonooxy)-1,6-dioxaspiro(4.5)dec-7-yl)-1-propenyl)-2-oxazolyl)butyl)-4-deoxy-4-(dimethylamino)-5-O-methyl-

Targets

Known targets for this compound

Species Target name Source Bibliographic reference
Mus musculus RAR-related orphan receptor gamma Starlite/ChEMBL No references
Homo sapiens APEX nuclease (multifunctional DNA repair enzyme) 1 Starlite/ChEMBL No references
Gallus gallus Serine-threonine protein phosphatase 2A regulatory subunit Starlite/ChEMBL References
Trypanosoma cruzi serine/threonine-protein phosphatase PP1 beta Curated by TDR Targets No references
Trypanosoma cruzi serine/threonine-protein phosphatase PP1, putative Curated by TDR Targets No references
Trypanosoma cruzi serine/threonine-protein phosphatase PP1, putative Curated by TDR Targets No references
Trypanosoma cruzi serine/threonine-protein phosphatase PP1, putative Curated by TDR Targets No references
Rattus norvegicus Inositol monophosphatase 1 Starlite/ChEMBL No references
Trypanosoma cruzi serine/threonine-protein phosphatase PP1, putative Curated by TDR Targets No references
Homo sapiens huntingtin Starlite/ChEMBL No references
Trypanosoma cruzi serine/threonine-protein phosphatase PP1, putative Curated by TDR Targets No references
Homo sapiens protein phosphatase 1, catalytic subunit, gamma isozyme Starlite/ChEMBL References
Trypanosoma cruzi serine/threonine-protein phosphatase PP1 alpha Curated by TDR Targets No references
Homo sapiens protein phosphatase 2, regulatory subunit B', alpha Starlite/ChEMBL No references
Trypanosoma cruzi serine/threonine-protein phosphatase PP1 alpha Curated by TDR Targets No references
Homo sapiens protein tyrosine phosphatase, non-receptor type 1 Starlite/ChEMBL References
Trypanosoma cruzi serine/threonine-protein phosphatase PP1 Curated by TDR Targets No references

Predicted pathogen targets for this compound

By orthology
Species Potential target Known druggable target/s Ortholog Group
Schistosoma japonicum expressed protein Get druggable targets OG5_129030 All targets in OG5_129030
Echinococcus granulosus serine:threonine protein phosphatase PP1 gamma Get druggable targets OG5_126821 All targets in OG5_126821
Toxoplasma gondii exonuclease III APE Get druggable targets OG5_126768 All targets in OG5_126768
Trichomonas vaginalis serine/threonine protein phosphatase, putative Get druggable targets OG5_126821 All targets in OG5_126821
Trypanosoma brucei gambiense serine/threonine protein phosphatase PP1, putative Get druggable targets OG5_152628 All targets in OG5_152628
Loa Loa (eye worm) hypothetical protein Get druggable targets OG5_132837 All targets in OG5_132837
Loa Loa (eye worm) exodeoxyribonuclease III family protein Get druggable targets OG5_126768 All targets in OG5_126768
Echinococcus multilocularis Serine threonine specific protein phosphatase bis(5 nucleosyl) tetraphosphatase Get druggable targets OG5_126821 All targets in OG5_126821
Trichomonas vaginalis protein phosphatase 2A, regulatory subunit, putative Get druggable targets OG5_126813 All targets in OG5_126813
Echinococcus granulosus inositol monophosphatase 1 Get druggable targets OG5_126810 All targets in OG5_126810
Trichomonas vaginalis protein phosphatase, caeel, putative Get druggable targets OG5_129030 All targets in OG5_129030
Mycobacterium tuberculosis Probable exodeoxyribonuclease III protein XthA (exonuclease III) (EXO III) (AP endonuclease VI) Get druggable targets OG5_126768 All targets in OG5_126768
Trypanosoma cruzi serine/threonine-protein phosphatase PP1, putative Get druggable targets OG5_129030 All targets in OG5_129030
Leishmania mexicana apurinic/apyrimidinic endonuclease-redox protein,AP-endonuclease Get druggable targets OG5_126768 All targets in OG5_126768
Trichomonas vaginalis protein phosphatase 2A, caeel, putative Get druggable targets OG5_129030 All targets in OG5_129030
Leishmania braziliensis protein phosphatase 2A regulatory subunit, putative Get druggable targets OG5_126981 All targets in OG5_126981
Leishmania infantum protein phosphatase 2A regulatory subunit, putative Get druggable targets OG5_126981 All targets in OG5_126981
Loa Loa (eye worm) inositol-1 Get druggable targets OG5_126810 All targets in OG5_126810
Schistosoma japonicum Serine/threonine-protein phosphatase PP1-gamma catalytic subunit, putative Get druggable targets OG5_129030 All targets in OG5_129030
Trichomonas vaginalis protein phosphatase-7, putative Get druggable targets OG5_129030 All targets in OG5_129030
Trichomonas vaginalis protein phosphatase-1, putative Get druggable targets OG5_129030 All targets in OG5_129030
Giardia lamblia Phosphatase Get druggable targets OG5_126821 All targets in OG5_126821
Trichomonas vaginalis protein phosphatase-1, putative Get druggable targets OG5_129030 All targets in OG5_129030
Onchocerca volvulus Huntingtin homolog Get druggable targets OG5_132837 All targets in OG5_132837
Onchocerca volvulus Get druggable targets OG5_129030 All targets in OG5_129030
Trichomonas vaginalis protein phosphatase, caeel, putative Get druggable targets OG5_129030 All targets in OG5_129030
Trichomonas vaginalis protein phosphatase-7, putative Get druggable targets OG5_129030 All targets in OG5_129030
Trichomonas vaginalis protein phsophatase-2A, putative Get druggable targets OG5_129030 All targets in OG5_129030
Brugia malayi Protein-tyrosine phosphatase containing protein Get druggable targets OG5_133865 All targets in OG5_133865
Candida albicans potential calcineurin-like phosphoesterase similar to S. cerevisiae GLC7 (YER133W) protein phosphatase involved in glycogen accu Get druggable targets OG5_126821 All targets in OG5_126821
Trichomonas vaginalis protein phosphatase-5, putative Get druggable targets OG5_129030 All targets in OG5_129030
Brugia malayi Ser/Thr protein phosphatase family protein Get druggable targets OG5_129030 All targets in OG5_129030
Echinococcus multilocularis inositol monophosphatase 1 Get druggable targets OG5_126810 All targets in OG5_126810
Schistosoma japonicum ko:K06269 protein phosphatase 1, catalytic subunit, putative Get druggable targets OG5_126821 All targets in OG5_126821
Neospora caninum GE25516, related Get druggable targets OG5_126813 All targets in OG5_126813
Plasmodium yoelii putative AP endonuclease-related Get druggable targets OG5_126768 All targets in OG5_126768
Trypanosoma brucei gambiense serine/threonine protein phosphatase PP1, putative Get druggable targets OG5_140695 All targets in OG5_140695
Entamoeba histolytica serine/threonine protein phosphatase PP1-2, putative Get druggable targets OG5_126821 All targets in OG5_126821
Candida albicans probable regulatory subunit B of protein serine/threonine phosphatase 2A (PP2A) similar to S. cerevisiae RTS1 (YOR014W) Get druggable targets OG5_126813 All targets in OG5_126813
Schistosoma mansoni protein phosphatase type 1 Get druggable targets OG5_126821 All targets in OG5_126821
Trypanosoma congolense apurinic/apyrimidinic endonuclease, putative Get druggable targets OG5_126768 All targets in OG5_126768
Trypanosoma cruzi serine/threonine-protein phosphatase PP1, putative Get druggable targets OG5_140695 All targets in OG5_140695
Echinococcus multilocularis serine:threonine protein phosphatase PP1 gamma Get druggable targets OG5_126821 All targets in OG5_126821
Leishmania braziliensis serine/threonine protein phosphatase pp1(5.9), putative Get druggable targets OG5_140695 All targets in OG5_140695
Schistosoma japonicum expressed protein Get druggable targets OG5_133865 All targets in OG5_133865
Wolbachia endosymbiont of Brugia malayi fructose-1,6-bisphosphatase Get druggable targets OG5_126810 All targets in OG5_126810
Trichomonas vaginalis protein phosphatase, caeel, putative Get druggable targets OG5_129030 All targets in OG5_129030
Leishmania mexicana serine/threonine protein phosphatase catalytic subunit, putative Get druggable targets OG5_126821 All targets in OG5_126821
Entamoeba histolytica myo-inositol monophosphatase, putative Get druggable targets OG5_126810 All targets in OG5_126810
Trichomonas vaginalis phosphoserine/threonine phosphatase, putative Get druggable targets OG5_129030 All targets in OG5_129030
Loa Loa (eye worm) hypothetical protein Get druggable targets OG5_129030 All targets in OG5_129030
Cryptosporidium parvum serine/threonine protein phosphatase, putative Get druggable targets OG5_126821 All targets in OG5_126821
Trichomonas vaginalis protein phosphatase-1, putative Get druggable targets OG5_126821 All targets in OG5_126821
Trichomonas vaginalis protein phosphatase, caeel, putative Get druggable targets OG5_129030 All targets in OG5_129030
Echinococcus multilocularis serine:threonine protein phosphatase 2A 56 kDa Get druggable targets OG5_126813 All targets in OG5_126813
Trichomonas vaginalis protein phosphatase 2A, regulatory subunit, putative Get druggable targets OG5_126813 All targets in OG5_126813
Leishmania infantum serine/threonine protein phosphatase pp1(5.9), putative Get druggable targets OG5_140695 All targets in OG5_140695
Schistosoma japonicum ko:K10771 AP endonuclease 1, putative Get druggable targets OG5_126768 All targets in OG5_126768
Trypanosoma brucei serine threonine-protein phosphatase PP1, putative Get druggable targets OG5_129030 All targets in OG5_129030
Trypanosoma brucei gambiense inositol-1(or 4)-monophosphatase 1, putative Get druggable targets OG5_126810 All targets in OG5_126810
Schistosoma mansoni ap endonuclease Get druggable targets OG5_126768 All targets in OG5_126768
Trypanosoma brucei protein phosphatase 1 Get druggable targets OG5_140695 All targets in OG5_140695
Echinococcus granulosus serine:threonine protein phosphatase Get druggable targets OG5_126821 All targets in OG5_126821
Trichomonas vaginalis bsu-protein phosphatase, putative Get druggable targets OG5_129030 All targets in OG5_129030
Trichomonas vaginalis protein phosphatase, caeel, putative Get druggable targets OG5_129030 All targets in OG5_129030
Trichomonas vaginalis protein phosphatase-7, putative Get druggable targets OG5_129030 All targets in OG5_129030
Leishmania mexicana hypothetical protein, conserved Get druggable targets OG5_126981 All targets in OG5_126981
Plasmodium berghei serine/threonine protein phosphatase PP1 Get druggable targets OG5_126821 All targets in OG5_126821
Trichomonas vaginalis bsu-protein phosphatase, putative Get druggable targets OG5_129030 All targets in OG5_129030
Leishmania mexicana serine/threonine protein phosphatase pp1(5.9), putative Get druggable targets OG5_140695 All targets in OG5_140695
Mycobacterium leprae possible inositol monophosphatase SubH (IMPase) (inositol-1-phosphatase) (I-1-Pase ). Get druggable targets OG5_126810 All targets in OG5_126810
Leishmania infantum serine/threonine protein phosphatase catalytic subunit, putative Get druggable targets OG5_126821 All targets in OG5_126821
Trypanosoma cruzi serine/threonine protein phosphatase catalytic subunit, putative Get druggable targets OG5_126821 All targets in OG5_126821
Trichomonas vaginalis protein phsophatase-2A, putative Get druggable targets OG5_129030 All targets in OG5_129030
Loa Loa (eye worm) hypothetical protein Get druggable targets OG5_129030 All targets in OG5_129030
Leishmania donovani protein phosphatase 2A regulatory subunit, putative Get druggable targets OG5_126981 All targets in OG5_126981
Trypanosoma cruzi myo-inositol-1(or 4)-monophosphatase 1, putative Get druggable targets OG5_126810 All targets in OG5_126810
Mycobacterium ulcerans exodeoxyribonuclease III protein XthA Get druggable targets OG5_126768 All targets in OG5_126768
Entamoeba histolytica serine/threonine protein phosphatase PP1-2, putative Get druggable targets OG5_126821 All targets in OG5_126821
Schistosoma mansoni protein phosphatase-1 Get druggable targets OG5_126821 All targets in OG5_126821
Echinococcus multilocularis protein phosphatase 1 catalytic subunit Get druggable targets OG5_126821 All targets in OG5_126821
Trichomonas vaginalis inositol monophosphatase, putative Get druggable targets OG5_126810 All targets in OG5_126810
Trichomonas vaginalis protein phosphatase-7, caeel, putative Get druggable targets OG5_129030 All targets in OG5_129030
Echinococcus multilocularis protein phosphatase pp2a regulatory subunit b Get druggable targets OG5_126981 All targets in OG5_126981
Leishmania braziliensis hypothetical protein, conserved Get druggable targets OG5_126981 All targets in OG5_126981
Trichomonas vaginalis protein phosphatase 2A, caeel, putative Get druggable targets OG5_129030 All targets in OG5_129030
Leishmania mexicana serine/threonine-protein phosphatase PP1, putative Get druggable targets OG5_129030 All targets in OG5_129030
Leishmania donovani serine/threonine protein phosphatase catalytic subunit, putative Get druggable targets OG5_126821 All targets in OG5_126821
Brugia malayi serine/threonine protein phosphatase 2A Get druggable targets OG5_126981 All targets in OG5_126981
Echinococcus multilocularis serine:threonine protein phosphatase PP1 gamma Get druggable targets OG5_126821 All targets in OG5_126821
Trypanosoma congolense hypothetical protein, conserved Get druggable targets OG5_126981 All targets in OG5_126981
Trypanosoma brucei gambiense serine/threonine protein phosphatase PP1 Get druggable targets OG5_140695 All targets in OG5_140695
Trichomonas vaginalis protein phosphatase, caeel, putative Get druggable targets OG5_129030 All targets in OG5_129030
Schistosoma japonicum similar to Serine/threonine-protein phosphatase 2A 55 kDa regulatory subunit B alpha isoform, putative Get druggable targets OG5_126981 All targets in OG5_126981
Schistosoma japonicum ko:K06269 protein phosphatase 1, catalytic subunit, putative Get druggable targets OG5_126821 All targets in OG5_126821
Leishmania major serine/threonine protein phosphatase pp1(5.9), putative Get druggable targets OG5_140695 All targets in OG5_140695
Brugia malayi delta isoform of regulatory subunit B56, protein phosphatase 2A Get druggable targets OG5_126813 All targets in OG5_126813
Plasmodium vivax serine/threonine protein phosphatase PP1, putative Get druggable targets OG5_126821 All targets in OG5_126821
Trichomonas vaginalis bsu-protein phosphatase, putative Get druggable targets OG5_126821 All targets in OG5_126821
Trypanosoma cruzi hypothetical protein, conserved Get druggable targets OG5_126981 All targets in OG5_126981
Trypanosoma cruzi protein phosphatase 2A regulatory subunit, putative Get druggable targets OG5_126981 All targets in OG5_126981
Toxoplasma gondii serine/threonine phosophatase PP1 Get druggable targets OG5_126821 All targets in OG5_126821
Cryptosporidium parvum putative protein phosphatase 2A regulatory B subunit Get druggable targets OG5_126813 All targets in OG5_126813
Trichomonas vaginalis protein phosphatase-2B, putative Get druggable targets OG5_129030 All targets in OG5_129030
Trichomonas vaginalis protein phsophatase-2A, putative Get druggable targets OG5_129030 All targets in OG5_129030
Trypanosoma brucei protein phosphatase 1, putative Get druggable targets OG5_126821 All targets in OG5_126821
Trypanosoma congolense protein phosphatase 1 Get druggable targets OG5_140695 All targets in OG5_140695
Schistosoma japonicum ko:K10772 AP endonuclease 2, putative Get druggable targets OG5_126768 All targets in OG5_126768
Trichomonas vaginalis protein phosphatase, caeel, putative Get druggable targets OG5_129030 All targets in OG5_129030
Trichomonas vaginalis serine/threonine protein phosphatase, putative Get druggable targets OG5_126821 All targets in OG5_126821
Brugia malayi Inositol-1 Get druggable targets OG5_126810 All targets in OG5_126810
Onchocerca volvulus Huntingtin homolog Get druggable targets OG5_132837 All targets in OG5_132837
Loa Loa (eye worm) serine/threonine-protein phosphatase PP1-beta Get druggable targets OG5_126821 All targets in OG5_126821
Cryptosporidium hominis dna-(apurinic or apyrimidinic site) lyase Get druggable targets OG5_126768 All targets in OG5_126768
Loa Loa (eye worm) serine/threonine protein phosphatase 2A Get druggable targets OG5_126981 All targets in OG5_126981
Trypanosoma cruzi serine/threonine-protein phosphatase PP1, putative Get druggable targets OG5_129030 All targets in OG5_129030
Leishmania braziliensis serine/threonine protein phosphatase catalytic subunit, putative Get druggable targets OG5_126821 All targets in OG5_126821
Echinococcus granulosus tyrosine protein phosphatase non receptor type Get druggable targets OG5_133865 All targets in OG5_133865
Trichomonas vaginalis protein phosphatase pp2a regulatory subunit B, putative Get druggable targets OG5_126981 All targets in OG5_126981
Leishmania major serine/threonine-protein phosphatase PP1, putative Get druggable targets OG5_129030 All targets in OG5_129030
Babesia bovis protein phosphatase B regulatory subunit, putative Get druggable targets OG5_126813 All targets in OG5_126813
Trichomonas vaginalis serine/threonine protein phosphatase, putative Get druggable targets OG5_129030 All targets in OG5_129030
Entamoeba histolytica exodeoxyribonuclease III, putative Get druggable targets OG5_126768 All targets in OG5_126768
Trichomonas vaginalis protein phsophatase-2A, putative Get druggable targets OG5_129030 All targets in OG5_129030
Plasmodium knowlesi serine/threonine protein phosphatase PP1, putative Get druggable targets OG5_126821 All targets in OG5_126821
Trichomonas vaginalis protein phosphatase-7, putative Get druggable targets OG5_129030 All targets in OG5_129030
Echinococcus multilocularis protein phosphatase 1 catalytic subunit Get druggable targets OG5_126821 All targets in OG5_126821
Leishmania braziliensis myo-inositol-1(or 4)-monophosphatase 1, putative Get druggable targets OG5_126810 All targets in OG5_126810
Leishmania donovani serine/threonine-protein phosphatase PP1, putative Get druggable targets OG5_152628 All targets in OG5_152628
Candida albicans subunit of protein phosphatase 2A Get druggable targets OG5_126981 All targets in OG5_126981
Trichomonas vaginalis bsu-protein phosphatase, putative Get druggable targets OG5_126821 All targets in OG5_126821
Trichomonas vaginalis protein phsophatase-2A, putative Get druggable targets OG5_129030 All targets in OG5_129030
Candida albicans probable regulatory subunit B of protein serine/threonine phosphatase 2A (PP2A) similar to S. cerevisiae RTS1 (YOR014W) Get druggable targets OG5_126813 All targets in OG5_126813
Trypanosoma cruzi hypothetical protein, conserved Get druggable targets OG5_126981 All targets in OG5_126981
Echinococcus granulosus serine:threonine protein phosphatase 2A 56 kDa Get druggable targets OG5_126813 All targets in OG5_126813
Onchocerca volvulus Get druggable targets OG5_152628 All targets in OG5_152628
Loa Loa (eye worm) hypothetical protein Get druggable targets OG5_126821 All targets in OG5_126821
Loa Loa (eye worm) hypothetical protein Get druggable targets OG5_132837 All targets in OG5_132837
Trypanosoma cruzi myo-inositol-1(or 4)-monophosphatase 1, putative Get druggable targets OG5_126810 All targets in OG5_126810
Trichomonas vaginalis protein phosphatase-1, putative Get druggable targets OG5_129030 All targets in OG5_129030
Trichomonas vaginalis protein phosphatase, caeel, putative Get druggable targets OG5_129030 All targets in OG5_129030
Trypanosoma cruzi apurinic/apyrimidinic endonuclease Get druggable targets OG5_126768 All targets in OG5_126768
Trichomonas vaginalis bsu-protein phosphatase, putative Get druggable targets OG5_126821 All targets in OG5_126821
Plasmodium falciparum serine/threonine protein phosphatase PP1 Get druggable targets OG5_126821 All targets in OG5_126821
Trypanosoma cruzi apurinic/apyrimidinic endonuclease, putative Get druggable targets OG5_126768 All targets in OG5_126768
Onchocerca volvulus Get druggable targets OG5_129030 All targets in OG5_129030
Loa Loa (eye worm) protein-tyrosine phosphatase Get druggable targets OG5_133865 All targets in OG5_133865
Trichomonas vaginalis protein phosphatase PP2A regulatory subunit B, putative Get druggable targets OG5_126981 All targets in OG5_126981
Trichomonas vaginalis phosphoserine/threonine phosphatase, putative Get druggable targets OG5_129030 All targets in OG5_129030
Candida albicans similar to S. cerevisiae APN2 (YBL019W) DNA repair apurinic/apyrimidinic endonuclease Get druggable targets OG5_126768 All targets in OG5_126768
Trichomonas vaginalis serine/threonine protein phosphatase, putative Get druggable targets OG5_129030 All targets in OG5_129030
Babesia bovis Ser/Thr protein phosphatase family protein Get druggable targets OG5_126821 All targets in OG5_126821
Loa Loa (eye worm) hypothetical protein Get druggable targets OG5_126813 All targets in OG5_126813
Trichomonas vaginalis protein phosphatase-7, putative Get druggable targets OG5_129030 All targets in OG5_129030
Trichomonas vaginalis protein phosphatase, caeel, putative Get druggable targets OG5_129030 All targets in OG5_129030
Trichomonas vaginalis protein phsophatase-2A, putative Get druggable targets OG5_129030 All targets in OG5_129030
Echinococcus granulosus protein phosphatase 1 catalytic subunit Get druggable targets OG5_126821 All targets in OG5_126821
Trypanosoma brucei protein phosphatase 1 Get druggable targets OG5_140695 All targets in OG5_140695
Toxoplasma gondii inositol(myo)-1(or 4)-monophosphatase 2, putative Get druggable targets OG5_126810 All targets in OG5_126810
Trichomonas vaginalis protein phosphatase-1, putative Get druggable targets OG5_129030 All targets in OG5_129030
Trypanosoma brucei gambiense protein phosphatase 2A regulatory subunit, putative Get druggable targets OG5_126981 All targets in OG5_126981
Echinococcus granulosus serine:threonine protein phosphatase PP1 gamma Get druggable targets OG5_126821 All targets in OG5_126821
Schistosoma mansoni inositol monophosphatase Get druggable targets OG5_126810 All targets in OG5_126810
Loa Loa (eye worm) serine/threonine protein phosphatase PP1-beta catalytic subunit Get druggable targets OG5_126821 All targets in OG5_126821
Schistosoma mansoni protein tyrosine phosphatase non-receptor type nt1 Get druggable targets OG5_133865 All targets in OG5_133865
Trichomonas vaginalis protein phosphatase-1, putative Get druggable targets OG5_129030 All targets in OG5_129030
Loa Loa (eye worm) protein phosphatase 2A regulatory subunit B' delta isoform Get druggable targets OG5_126813 All targets in OG5_126813
Leishmania braziliensis serine/threonine-protein phosphatase PP1, putative Get druggable targets OG5_152628 All targets in OG5_152628
Trypanosoma cruzi serine/threonine-protein phosphatase PP1 alpha Get druggable targets OG5_129030 All targets in OG5_129030
Giardia lamblia Endonuclease/Exonuclease/phosphatase Get druggable targets OG5_126768 All targets in OG5_126768
Onchocerca volvulus Protein phosphatase PP2A 55 kDa regulatory subunit homolog Get druggable targets OG5_126981 All targets in OG5_126981
Trypanosoma congolense serine/threonine protein phosphatase PP1, putative Get druggable targets OG5_140695 All targets in OG5_140695
Leishmania donovani apurinic/apyrimidinic endonuclease-redox protein Get druggable targets OG5_126768 All targets in OG5_126768
Trichomonas vaginalis protein phosphatase-7, putative Get druggable targets OG5_129030 All targets in OG5_129030
Loa Loa (eye worm) hypothetical protein Get druggable targets OG5_129030 All targets in OG5_129030
Trichomonas vaginalis bsu-protein phosphatase, putative Get druggable targets OG5_129030 All targets in OG5_129030
Echinococcus granulosus serine:threonine protein phosphatase 2A 56 kDa Get druggable targets OG5_126813 All targets in OG5_126813
Mycobacterium ulcerans extragenic suppressor protein SuhB Get druggable targets OG5_126810 All targets in OG5_126810
Echinococcus granulosus protein phosphatase 1 catalytic subunit Get druggable targets OG5_126821 All targets in OG5_126821
Neospora caninum hypothetical protein Get druggable targets OG5_126768 All targets in OG5_126768
Loa Loa (eye worm) hypothetical protein Get druggable targets OG5_129030 All targets in OG5_129030
Echinococcus granulosus serine:threonine protein phosphatase PP1 beta Get druggable targets OG5_126821 All targets in OG5_126821
Giardia lamblia Protein phosphatase 2A B regulatory subunit Wdb1 Get druggable targets OG5_126813 All targets in OG5_126813
Trypanosoma brucei gambiense hypothetical protein, conserved Get druggable targets OG5_126981 All targets in OG5_126981
Leishmania infantum serine/threonine-protein phosphatase PP1, putative Get druggable targets OG5_152628 All targets in OG5_152628
Leishmania infantum serine/threonine-protein phosphatase PP1, putative Get druggable targets OG5_129030 All targets in OG5_129030
Trypanosoma congolense protein phosphatase 2A regulatory subunit, putative Get druggable targets OG5_126981 All targets in OG5_126981
Neospora caninum hypothetical protein Get druggable targets OG5_126821 All targets in OG5_126821
Theileria parva hypothetical protein Get druggable targets OG5_126768 All targets in OG5_126768
Schistosoma mansoni ap endonuclease Get druggable targets OG5_126768 All targets in OG5_126768
Theileria parva serine/threonine protein phosphatase, putative Get druggable targets OG5_126821 All targets in OG5_126821
Trypanosoma cruzi serine/threonine-protein phosphatase PP1 beta Get druggable targets OG5_152628 All targets in OG5_152628
Trichomonas vaginalis ap endonuclease, putative Get druggable targets OG5_126768 All targets in OG5_126768
Neospora caninum hypothetical protein Get druggable targets OG5_126810 All targets in OG5_126810
Schistosoma mansoni protein phosphatase 2a regulatory subunit Get druggable targets OG5_126813 All targets in OG5_126813
Brugia malayi Serine/threonine protein phosphatase 2A, 56 kDa regulatory subunit,epsilon isoform Get druggable targets OG5_126813 All targets in OG5_126813
Theileria parva hypothetical protein Get druggable targets OG5_126813 All targets in OG5_126813
Leishmania braziliensis apurinic/apyrimidinic endonuclease-redox protein Get druggable targets OG5_126768 All targets in OG5_126768
Schistosoma mansoni protein phosphatase-1 Get druggable targets OG5_129030 All targets in OG5_129030
Leishmania major myo-inositol-1(or 4)-monophosphatase 1, putative Get druggable targets OG5_126810 All targets in OG5_126810
Echinococcus granulosus protein phosphatase pp2a regulatory subunit b Get druggable targets OG5_126981 All targets in OG5_126981
Brugia malayi hypothetical protein Get druggable targets OG5_132837 All targets in OG5_132837
Schistosoma japonicum similar to Serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit delta isoform, putative Get druggable targets OG5_126813 All targets in OG5_126813
Trichomonas vaginalis protein phosphatase-1, putative Get druggable targets OG5_129030 All targets in OG5_129030
Leishmania donovani myo-inositol-1(or 4)-monophosphatase 1, putative Get druggable targets OG5_126810 All targets in OG5_126810
Trichomonas vaginalis protein phosphatase-1, putative Get druggable targets OG5_129030 All targets in OG5_129030
Cryptosporidium hominis hypothetical protein Get druggable targets OG5_126821 All targets in OG5_126821
Schistosoma japonicum DNA-(apurinic or apyrimidinic site) lyase 2, putative Get druggable targets OG5_126768 All targets in OG5_126768
Echinococcus multilocularis Serine threonine specific protein phosphatase bis(5 nucleosyl) tetraphosphatase Get druggable targets OG5_126821 All targets in OG5_126821
Trichomonas vaginalis bsu-protein phosphatase, putative Get druggable targets OG5_129030 All targets in OG5_129030
Brugia malayi exodeoxyribonuclease III family protein Get druggable targets OG5_126768 All targets in OG5_126768
Trichomonas vaginalis serine/threonine-protein phosphatase 2A 55 kDa regulatory subunit B gamma isoform, putative Get druggable targets OG5_126981 All targets in OG5_126981
Leishmania braziliensis serine/threonine-protein phosphatase PP1, putative Get druggable targets OG5_129030 All targets in OG5_129030
Trichomonas vaginalis protein phosphatase-5, putative Get druggable targets OG5_129030 All targets in OG5_129030
Plasmodium falciparum AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative Get druggable targets OG5_126768 All targets in OG5_126768
Trichomonas vaginalis serine/threonine protein phosphatase, putative Get druggable targets OG5_129030 All targets in OG5_129030
Candida albicans similar to S. cerevisiae APN2 (YBL019W) DNA repair apurinic/apyrimidinic endonuclease Get druggable targets OG5_126768 All targets in OG5_126768
Trypanosoma cruzi serine/threonine-protein phosphatase PP1 alpha Get druggable targets OG5_129030 All targets in OG5_129030
Leishmania mexicana serine/threonine-protein phosphatase PP1, putative Get druggable targets OG5_152628 All targets in OG5_152628
Loa Loa (eye worm) hypothetical protein Get druggable targets OG5_129030 All targets in OG5_129030
Leishmania major serine/threonine protein phosphatase catalytic subunit, putative Get druggable targets OG5_126821 All targets in OG5_126821
Schistosoma japonicum ko:K06269 protein phosphatase 1, catalytic subunit, putative Get druggable targets OG5_126821 All targets in OG5_126821
Schistosoma japonicum ko:K05696 protein tyrosine phosphatase, non-receptor type 1, putative Get druggable targets OG5_133865 All targets in OG5_133865
Trypanosoma brucei apurinic/apyrimidinic endonuclease, putative Get druggable targets OG5_126768 All targets in OG5_126768
Leishmania donovani hypothetical protein, conserved Get druggable targets OG5_126981 All targets in OG5_126981
Plasmodium vivax AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative Get druggable targets OG5_126768 All targets in OG5_126768
Schistosoma mansoni protein phosphatase pp2a regulatory subunit B Get druggable targets OG5_126981 All targets in OG5_126981
Schistosoma mansoni inositol monophosphatase Get druggable targets OG5_126810 All targets in OG5_126810
Giardia lamblia Protein phosphatase PP2A regulatory subunit B Get druggable targets OG5_126981 All targets in OG5_126981
Trypanosoma brucei protein phosphatase 2A regulatory subunit, putative Get druggable targets OG5_126981 All targets in OG5_126981
Trypanosoma cruzi serine/threonine-protein phosphatase PP1, putative Get druggable targets OG5_129030 All targets in OG5_129030
Schistosoma mansoni protein phosphatase-1 Get druggable targets OG5_126821 All targets in OG5_126821
Echinococcus granulosus protein phosphatase 1, catalytic subunit, beta isozyme Get druggable targets OG5_126821 All targets in OG5_126821
Trichomonas vaginalis protein phosphatase-1, putative Get druggable targets OG5_129030 All targets in OG5_129030
Leishmania major serine/threonine-protein phosphatase PP1, putative Get druggable targets OG5_152628 All targets in OG5_152628
Wolbachia endosymbiont of Brugia malayi exonuclease III Get druggable targets OG5_126768 All targets in OG5_126768
Echinococcus granulosus protein phosphatase 2a regulatory subunit Get druggable targets OG5_126813 All targets in OG5_126813
Trichomonas vaginalis myo inositol monophosphatase, putative Get druggable targets OG5_126810 All targets in OG5_126810
Plasmodium knowlesi AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative Get druggable targets OG5_126768 All targets in OG5_126768
Trichomonas vaginalis myo inositol monophosphatase, putative Get druggable targets OG5_126810 All targets in OG5_126810
Trichomonas vaginalis protein phosphatase 2A, caeel, putative Get druggable targets OG5_129030 All targets in OG5_129030
Leishmania mexicana myo-inositol-1(or 4)-monophosphatase 1, putative Get druggable targets OG5_126810 All targets in OG5_126810
Leishmania infantum myo-inositol-1(or 4)-monophosphatase 1, putative Get druggable targets OG5_126810 All targets in OG5_126810
Schistosoma japonicum ko:K01092 myo-inositol-1(or 4)-monophosphatase [EC3.1.3.25], putative Get druggable targets OG5_126810 All targets in OG5_126810
Echinococcus multilocularis protein phosphatase 2a regulatory subunit Get druggable targets OG5_126813 All targets in OG5_126813
Giardia lamblia Ser/Thr protein phosphatase PP1-alpha 2 catalytic subunit Get druggable targets OG5_126821 All targets in OG5_126821
Leishmania major hypothetical protein, conserved Get druggable targets OG5_126981 All targets in OG5_126981
Trypanosoma brucei gambiense serine/threonine protein phosphatase catalytic subunit, putative,serine/threonine protein phosphatase PP1-gamma Get druggable targets OG5_126821 All targets in OG5_126821
Trypanosoma brucei protein phoshatase 1, putative Get druggable targets OG5_152628 All targets in OG5_152628
Leishmania infantum apurinic/apyrimidinic endonuclease-redox protein Get druggable targets OG5_126768 All targets in OG5_126768
Trichomonas vaginalis protein phsophatase-2A, putative Get druggable targets OG5_129030 All targets in OG5_129030
Leishmania major apurinic/apyrimidinic endonuclease-redox protein Get druggable targets OG5_126768 All targets in OG5_126768
Trichomonas vaginalis serine/threonine protein phosphatase, putative Get druggable targets OG5_129030 All targets in OG5_129030
Brugia malayi Ser/Thr protein phosphatase family protein Get druggable targets OG5_129030 All targets in OG5_129030
Echinococcus multilocularis tyrosine protein phosphatase non receptor type Get druggable targets OG5_133865 All targets in OG5_133865
Trypanosoma cruzi serine/threonine-protein phosphatase PP1, putative Get druggable targets OG5_152628 All targets in OG5_152628
Mycobacterium tuberculosis Inositol-1-monophosphatase SuhB Get druggable targets OG5_126810 All targets in OG5_126810
Echinococcus granulosus DNA apurinic or apyrimidinic site lyase Get druggable targets OG5_126768 All targets in OG5_126768
Trypanosoma brucei inositol-1(or 4)-monophosphatase 1, putative Get druggable targets OG5_126810 All targets in OG5_126810
Trypanosoma congolense protein phosphatase 1, putative Get druggable targets OG5_126821 All targets in OG5_126821
Cryptosporidium parvum conserved hypothetical protein Get druggable targets OG5_126768 All targets in OG5_126768
Schistosoma mansoni protein phosphatase 2a regulatory subunit Get druggable targets OG5_126813 All targets in OG5_126813
Trichomonas vaginalis ap endonuclease, putative Get druggable targets OG5_126768 All targets in OG5_126768
Trypanosoma brucei hypothetical protein, conserved Get druggable targets OG5_126981 All targets in OG5_126981
Echinococcus multilocularis DNA (apurinic or apyrimidinic site) lyase Get druggable targets OG5_126768 All targets in OG5_126768
Loa Loa (eye worm) hypothetical protein Get druggable targets OG5_129030 All targets in OG5_129030
Echinococcus multilocularis serine:threonine protein phosphatase PP1 isozyme Get druggable targets OG5_126821 All targets in OG5_126821
Trichomonas vaginalis protein phosphatase, caeel, putative Get druggable targets OG5_126821 All targets in OG5_126821
Schistosoma japonicum similar to Serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit alpha isoform, putative Get druggable targets OG5_126813 All targets in OG5_126813
Trichomonas vaginalis protein phosphatase, caeel, putative Get druggable targets OG5_129030 All targets in OG5_129030
Leishmania infantum hypothetical protein, conserved Get druggable targets OG5_126981 All targets in OG5_126981
Leishmania donovani serine/threonine protein phosphatase pp1(5.9), putative Get druggable targets OG5_140695 All targets in OG5_140695
Brugia malayi Serine/threonine protein phosphatase F56C9.1 in chromosomeIII Get druggable targets OG5_126821 All targets in OG5_126821
Treponema pallidum exodeoxyribonuclease (exoA) Get druggable targets OG5_126768 All targets in OG5_126768
Trichomonas vaginalis protein phsophatase-2A, putative Get druggable targets OG5_129030 All targets in OG5_129030
Entamoeba histolytica protein phosphatase regulatory subunit, putative Get druggable targets OG5_126981 All targets in OG5_126981
Candida albicans potential calcineurin-like phosphoesterase similar to S. cerevisiae GLC7 (YER133W) protein phosphatase involved in glycogen accu Get druggable targets OG5_126821 All targets in OG5_126821
Brugia malayi Serine/threonine protein phosphatase PP1-beta catalytic subunit Get druggable targets OG5_126821 All targets in OG5_126821
Echinococcus multilocularis serine:threonine protein phosphatase PP1 beta Get druggable targets OG5_126821 All targets in OG5_126821
Trypanosoma brucei gambiense apurinic/apyrimidinic endonuclease, putative Get druggable targets OG5_126768 All targets in OG5_126768
Schistosoma mansoni protein phosphatase 2a regulatory subunit Get druggable targets OG5_126813 All targets in OG5_126813
Trypanosoma cruzi protein phosphatase 2A regulatory subunit, putative Get druggable targets OG5_126981 All targets in OG5_126981
Echinococcus multilocularis serine:threonine protein phosphatase 2A 56 kDa Get druggable targets OG5_126813 All targets in OG5_126813
Schistosoma japonicum DNA-(apurinic or apyrimidinic site) lyase 2, putative Get druggable targets OG5_126768 All targets in OG5_126768
Trichomonas vaginalis phosphoserine/threonine phosphatase, putative Get druggable targets OG5_129030 All targets in OG5_129030
Plasmodium berghei AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative Get druggable targets OG5_126768 All targets in OG5_126768
Leishmania mexicana protein phosphatase 2A regulatory subunit, putative Get druggable targets OG5_126981 All targets in OG5_126981
Candida albicans subunit of protein phosphatase 2A Get druggable targets OG5_126981 All targets in OG5_126981
Toxoplasma gondii protein phosphatase 2a regulatory b subunit (b56 family) protein Get druggable targets OG5_126813 All targets in OG5_126813
Trichomonas vaginalis protein phosphatase-7, caeel, putative Get druggable targets OG5_129030 All targets in OG5_129030
Plasmodium yoelii serine/threonine protein phosphatase alpha-3 isoform Get druggable targets OG5_126821 All targets in OG5_126821
Leishmania major protein phosphatase 2A regulatory subunit, putative Get druggable targets OG5_126981 All targets in OG5_126981
Trypanosoma congolense inositol-1(or 4)-monophosphatase 1, putative Get druggable targets OG5_126810 All targets in OG5_126810
Trichomonas vaginalis protein phosphatase 2A, caeel, putative Get druggable targets OG5_126821 All targets in OG5_126821
Schistosoma mansoni protein phosphatase type 1 Get druggable targets OG5_126821 All targets in OG5_126821
By sequence similarity to non orthologous known druggable targets
Species Potential target Known druggable target Length Alignment span Identity
Trypanosoma cruzi myo-inositol-1 phosphatase, putative Inositol monophosphatase 1   277 aa 284 aa 30.6 %
Brugia malayi Protein kinase domain containing protein Serine-threonine protein phosphatase 2A regulatory subunit   426 aa 474 aa 20.5 %
Plasmodium falciparum serine/threonine protein phosphatase 7 serine/threonine-protein phosphatase PP1 beta 330 aa 321 aa 27.7 %
Plasmodium falciparum serine/threonine protein phosphatase PP1 serine/threonine-protein phosphatase PP1, putative 294 aa 288 aa 58.7 %
Brugia malayi Inositol monophosphatase family protein Inositol monophosphatase 1   277 aa 238 aa 21.8 %
Plasmodium falciparum serine/threonine protein phosphatase PP1 serine/threonine-protein phosphatase PP1 alpha 297 aa 288 aa 60.1 %
Schistosoma japonicum ko:K01530 phospholipid-translocating ATPase [EC3.6.3.1], putative Serine-threonine protein phosphatase 2A regulatory subunit   426 aa 468 aa 45.7 %
Schistosoma mansoni protein phosphatase pp2a regulatory subunit B Serine-threonine protein phosphatase 2A regulatory subunit   426 aa 350 aa 38.9 %
Schistosoma mansoni pap-inositol-14-phosphatase Inositol monophosphatase 1   277 aa 279 aa 22.9 %
Trypanosoma brucei gambiense inositol-1(or 4)-monophosphatase, putative Inositol monophosphatase 1   277 aa 309 aa 27.8 %
Echinococcus multilocularis cleavage stimulation factor subunit 1 Serine-threonine protein phosphatase 2A regulatory subunit   426 aa 364 aa 19.5 %
Echinococcus granulosus cleavage stimulation factor subunit 1 Serine-threonine protein phosphatase 2A regulatory subunit   426 aa 364 aa 19.5 %
Entamoeba histolytica 3(2),5-bisphosphate nucleotidase, putative Inositol monophosphatase 1   277 aa 263 aa 24.0 %
Dictyostelium discoideum 3',5'-bisphosphate nucleotidase Inositol monophosphatase 1   277 aa 230 aa 25.2 %
Candida albicans one of two closely related genes similar to S. cerevisiae MET22/HAL2 (YOL064C) bisphosphate-3'-nucleotidase, implicated in salt Inositol monophosphatase 1   277 aa 307 aa 22.5 %
Trypanosoma congolense inositol-1(or 4)-monophosphatase, putative Inositol monophosphatase 1   277 aa 304 aa 28.9 %
Plasmodium falciparum protein phosphatase containing kelch-like domains protein phosphatase 1, catalytic subunit, gamma isozyme 337 aa 324 aa 42.6 %
Dictyostelium discoideum hypothetical protein Serine-threonine protein phosphatase 2A regulatory subunit   426 aa 366 aa 31.7 %
Dictyostelium discoideum 3',5'-bisphosphate nucleotidase 1 Inositol monophosphatase 1   277 aa 275 aa 22.2 %
Onchocerca volvulus Serine-threonine protein phosphatase 2A regulatory subunit   426 aa 444 aa 65.5 %
Onchocerca volvulus Inositol monophosphatase 1   277 aa 238 aa 22.7 %
Trypanosoma cruzi inositol polyphosphate 1-phosphatase, putative Inositol monophosphatase 1   277 aa 291 aa 23.7 %
Trichomonas vaginalis inositol monophosphatase, putative Inositol monophosphatase 1   277 aa 268 aa 22.4 %
Schistosoma japonicum ko:K01082 3'(2'), 5'-bisphosphate nucleotidase [EC3.1.3.7], putative Inositol monophosphatase 1   277 aa 275 aa 21.5 %
Trichomonas vaginalis diphosphonucleoside phosphohydrolase, putative Inositol monophosphatase 1   277 aa 263 aa 21.7 %
Schistosoma japonicum similar to Protein phosphatase PP2A 55 kDa regulatory subunit, putative Serine-threonine protein phosphatase 2A regulatory subunit   426 aa 353 aa 37.4 %
Schistosoma mansoni protein phosphatase 2a regulatory subunit Serine-threonine protein phosphatase 2A regulatory subunit   426 aa 350 aa 38.9 %
Plasmodium falciparum protein phosphatase containing kelch-like domains serine/threonine-protein phosphatase PP1, putative 351 aa 289 aa 40.1 %
Trichomonas vaginalis inositol monophosphatase, putative Inositol monophosphatase 1   277 aa 258 aa 21.7 %
Trichomonas vaginalis serine/threonine protein phosphatase 2A 57 kDa regulatory subunit B' beta isoform, putative protein phosphatase 2, regulatory subunit B', alpha 429 aa 372 aa 22.3 %
Plasmodium falciparum serine/threonine protein phosphatase PP1 serine/threonine-protein phosphatase PP1 alpha 169 aa 165 aa 60.0 %
Plasmodium falciparum serine/threonine protein phosphatase PP1 serine/threonine-protein phosphatase PP1, putative 294 aa 286 aa 59.1 %
Onchocerca volvulus Serine-threonine protein phosphatase 2A regulatory subunit   426 aa 355 aa 22.5 %
Onchocerca volvulus Putative 28S ribosomal protein S10, mitochondrial Inositol monophosphatase 1   277 aa 271 aa 46.1 %
Plasmodium falciparum serine/threonine protein phosphatase PP1 serine/threonine-protein phosphatase PP1, putative 294 aa 286 aa 59.1 %
Trypanosoma brucei inositol-1(or 4)-monophosphatase, putative Inositol monophosphatase 1   277 aa 304 aa 27.3 %
Plasmodium falciparum serine/threonine protein phosphatase PP1 serine/threonine-protein phosphatase PP1, putative 159 aa 157 aa 61.1 %
Trichomonas vaginalis myo inositol monophosphatase, putative Inositol monophosphatase 1   277 aa 276 aa 21.4 %
Onchocerca volvulus Putative trans-2-enoyl-CoA reductase 1, mitochondrial Inositol monophosphatase 1   277 aa 278 aa 23.0 %
Entamoeba histolytica 3(2),5-bisphosphate nucleotidase, putative Inositol monophosphatase 1   277 aa 287 aa 22.3 %
Trypanosoma brucei kinetoplastid-specific phospho-protein phosphatase, putative serine/threonine-protein phosphatase PP1 144 aa 162 aa 29.0 %
Candida albicans one of two closely related genes similar to S. cerevisiae MET22/HAL2 (YOL064C) bisphosphate-3'-nucleotidase, implicated in salt Inositol monophosphatase 1   277 aa 300 aa 22.0 %
Loa Loa (eye worm) hypothetical protein Inositol monophosphatase 1   277 aa 298 aa 23.8 %
Candida albicans one of two closely related genes similar to S. cerevisiae MET22/HAL2 (YOL064C) bisphosphate-3'-nucleotidase, implicated in salt Inositol monophosphatase 1   277 aa 306 aa 22.5 %
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Loa Loa (eye worm) 5-hydroxytryptamine 2C receptor 0.0116 0.0259 0.0671
Echinococcus multilocularis expressed conserved protein 0.0097 0.0208 0.0538
Echinococcus multilocularis rhodopsin orphan GPCR 0.0116 0.0259 0.0671
Echinococcus granulosus geminin 0.0678 0.1721 0.4479
Echinococcus multilocularis 7TM GPCR, rhodopsin 0.0116 0.0259 0.0671
Onchocerca volvulus 0.0116 0.0259 0.1312
Mycobacterium tuberculosis Lysyl-tRNA synthetase 2 LysX 0.0042 0.0066 0.0257
Schistosoma mansoni hypothetical protein 0.0019 0.0007 0.0005
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0116 0.0259 0.0258
Mycobacterium tuberculosis Probable aldehyde dehydrogenase 0.0069 0.0135 0.0881
Plasmodium vivax calcium-dependent protein kinase 4, putative 0.0068 0.0134 0.0549
Loa Loa (eye worm) ACC-1 protein 0.0061 0.0115 0.0296
Plasmodium falciparum calcium-dependent protein kinase 4 0.0068 0.0134 0.0549
Loa Loa (eye worm) hypothetical protein 0.0021 0.001 0.0022
Loa Loa (eye worm) hypothetical protein 0.0204 0.0487 0.1264
Onchocerca volvulus 0.0028 0.003 0.0119
Echinococcus granulosus protein phosphatase 1 catalytic subunit 0.0051 0.009 0.023
Schistosoma mansoni niemann-pick C1 (NPC1) 0.0104 0.0229 0.0227
Toxoplasma gondii eukaryotic aspartyl protease superfamily protein 0.0191 0.0455 0.2847
Leishmania major hypothetical protein, conserved 0.0071 0.0142 0.073
Loa Loa (eye worm) hypothetical protein 0.0021 0.001 0.0022
Plasmodium vivax calcium-dependent protein kinase 3, putative 0.0068 0.0134 0.0549
Echinococcus granulosus rhodopsin orphan GPCR 0.0116 0.0259 0.0671
Echinococcus granulosus retinoic acid receptor rxr beta a 0.0021 0.001 0.0022
Plasmodium falciparum ataxin-2 like protein, putative 0.0101 0.022 0.0904
Trichomonas vaginalis spcc417.12 protein, putative 0.0068 0.0135 0.2495
Plasmodium vivax serine/threonine protein phosphatase PP1, putative 0.0051 0.009 0.0367
Loa Loa (eye worm) serine/threonine protein phosphatase PP1-beta catalytic subunit 0.0051 0.009 0.023
Mycobacterium leprae Probable lipase LipE 0.0071 0.0142 1
Echinococcus granulosus tm gpcr rhodopsin 0.0116 0.0259 0.0671
Onchocerca volvulus 0.0068 0.0135 0.0665
Echinococcus granulosus tumor protein p63 0.033 0.0817 0.2124
Trichomonas vaginalis conserved hypothetical protein 0.0019 0.0007 0.0103
Schistosoma mansoni jumonji/arid domain-containing protein 0.012 0.0269 0.0267
Schistosoma mansoni glutamyl-tRNA synthetase cytoplasmic (glutamate--tRNA ligase) (glurs) 0.0067 0.013 0.0129
Echinococcus granulosus phd:f box containing protein 0.0032 0.004 0.01
Plasmodium vivax CDK-related protein kinase 6, putative 0.0944 0.2413 1
Leishmania major hypothetical protein, conserved 0.0032 0.004 0.0205
Echinococcus granulosus neuroligin 0.0068 0.0135 0.0347
Loa Loa (eye worm) hypothetical protein 0.0116 0.0259 0.0671
Plasmodium vivax JmjC domain containing protein 0.0032 0.004 0.0158
Echinococcus multilocularis snurportin 1 0.0259 0.0631 0.1638
Schistosoma mansoni topbp1 0.0019 0.0007 0.0005
Loa Loa (eye worm) hypothetical protein 0.0071 0.0142 0.0366
Entamoeba histolytica hypothetical protein 0.0106 0.0233 1
Brugia malayi Steroid receptor seven-up type 2 0.0021 0.001 0.0075
Trypanosoma brucei THT1 - hexose transporter, putative 0.0069 0.0136 0.0691
Trypanosoma brucei serine threonine-protein phosphatase PP1, putative 0.0047 0.0079 0.0395
Echinococcus granulosus family S9 non peptidase ue S09 family 0.0068 0.0135 0.0347
Echinococcus multilocularis rhodopsin orphan GPCR 0.0116 0.0259 0.0671
Loa Loa (eye worm) hypothetical protein 0.0068 0.0135 0.0347
Brugia malayi Dopamine receptor protein 1 0.0116 0.0259 0.2245
Echinococcus multilocularis tachykinin peptides receptor 99D 0.0428 0.1072 0.2787
Loa Loa (eye worm) hypothetical protein 0.0116 0.0259 0.0671
Trichomonas vaginalis sugar transporter, putative 0.0031 0.0038 0.0681
Toxoplasma gondii sugar transporter ST1 0.0031 0.0038 0.0229
Trypanosoma cruzi hexose transporter 0.0069 0.0136 0.07
Loa Loa (eye worm) glutamate-gated chloride channel alpha3A subunit 0.0028 0.003 0.0073
Schistosoma mansoni ap endonuclease 0.0038 0.0057 0.0055
Trichomonas vaginalis conserved hypothetical protein 0.0069 0.0136 0.2519
Mycobacterium tuberculosis Carboxylesterase LipT 0.0068 0.0135 0.0878
Mycobacterium leprae Possible lysyl-tRNA synthetase 2 LysX 0.005 0.0086 0.5832
Brugia malayi ecdysteroid receptor 0.0021 0.001 0.0075
Plasmodium falciparum replication factor C subunit 1, putative 0.0019 0.0007 0.0023
Echinococcus granulosus lamin 0.0027 0.0027 0.0064
Plasmodium vivax aspartyl proteinase, putative 0.0191 0.0455 0.1878
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0116 0.0259 0.0671
Mycobacterium ulcerans carboxylesterase, LipT 0.0068 0.0135 0.9466
Loa Loa (eye worm) hypothetical protein 0.0031 0.0038 0.0095
Schistosoma mansoni alzheimer's disease beta-amyloid related 0.0118 0.0263 0.0261
Echinococcus multilocularis nicotinic acetylcholine receptor beta 1 subunit 0.0061 0.0115 0.0296
Brugia malayi Pepsin A precursor 0.0191 0.0455 0.3946
Echinococcus multilocularis g-protein coupled receptor 0.0116 0.0259 0.0671
Echinococcus multilocularis tyrosine protein phosphatase non receptor type 0.0423 0.1059 0.2753
Loa Loa (eye worm) hypothetical protein 0.0031 0.0038 0.0095
Echinococcus granulosus somatostatin receptor 0.0116 0.0259 0.0671
Loa Loa (eye worm) hypothetical protein 0.0021 0.001 0.0022
Trichomonas vaginalis sugar transporter, putative 0.0031 0.0038 0.0681
Onchocerca volvulus 0.0116 0.0259 0.1312
Loa Loa (eye worm) jmjC domain-containing protein 0.012 0.0269 0.0696
Brugia malayi acetylcholine receptor alpha subunit precursor, putative 0.0061 0.0115 0.0989
Trichomonas vaginalis protein phsophatase-2A, putative 0.021 0.0504 0.9403
Echinococcus multilocularis lipoxygenase domain containing protein 0.0019 0.0007 0.0013
Schistosoma mansoni opsin-like receptor 0.0116 0.0259 0.0258
Loa Loa (eye worm) hypothetical protein 0.0071 0.0142 0.0366
Loa Loa (eye worm) aspartyl protease 6 0.0191 0.0455 0.118
Toxoplasma gondii ATPase, AAA family protein 0.0019 0.0007 0.0034
Loa Loa (eye worm) melatonin receptor type 1A 0.0116 0.0259 0.0671
Loa Loa (eye worm) jmjC domain-containing protein 0.0032 0.004 0.01
Echinococcus multilocularis calcium:calmodulin dependent protein kinase type 0.0068 0.0134 0.0344
Brugia malayi nicotinic acetylcholine receptor alpha subunit, putative 0.0061 0.0115 0.0989
Loa Loa (eye worm) hypothetical protein 0.0116 0.0259 0.0671
Trichomonas vaginalis sugar transporter, putative 0.0031 0.0038 0.0681
Brugia malayi hypothetical protein 0.0148 0.0342 0.2964
Brugia malayi calcium-independent alpha-latrotoxin receptor 2, putative 0.0048 0.0081 0.0687
Loa Loa (eye worm) hypothetical protein 0.0033 0.0042 0.0105
Brugia malayi excitatory GABA receptor EXP-1A 0.0061 0.0115 0.0989
Loa Loa (eye worm) serine/threonine protein phosphatase PP1-alpha catalytic subunit 0.0047 0.0079 0.02
Loa Loa (eye worm) pigment dispersing factor receptor c 0.015 0.0348 0.0902
Loa Loa (eye worm) hypothetical protein 0.0116 0.0259 0.0671
Echinococcus multilocularis DNA (apurinic or apyrimidinic site) lyase 0.0038 0.0057 0.0143
Schistosoma mansoni biogenic amine receptor 0.0116 0.0259 0.0258
Echinococcus multilocularis musashi 0.0027 0.0027 0.0064
Trichomonas vaginalis D-aminoacylase, putative 0.0071 0.0142 0.263
Loa Loa (eye worm) G-protein coupled receptor 0.0116 0.0259 0.0671
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0037 0.0052 0.0948
Trypanosoma cruzi importin beta-1 subunit, putative 0.002 0.0008 0.0041
Echinococcus multilocularis neuropeptides capa receptor 0.0116 0.0259 0.0671
Mycobacterium tuberculosis Conserved protein 0.0071 0.0142 0.0943
Echinococcus multilocularis diuretic hormone 44 receptor GPRdih2 0.0048 0.0081 0.0205
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0021 0.001 0.0075
Giardia lamblia Endonuclease/Exonuclease/phosphatase 0.0038 0.0057 0.3489
Trichomonas vaginalis prolyl-tRNA synthetase, putative 0.0067 0.013 0.241
Loa Loa (eye worm) hypothetical protein 0.0019 0.0007 0.0014
Brugia malayi Unidentified vitellogenin-linked transcript protein 6, putative 0.0116 0.0259 0.2245
Brugia malayi Neurotransmitter-gated ion-channel ligand binding domain containing protein 0.0028 0.003 0.0245
Echinococcus multilocularis FTZ F1 nuclear receptor protein 0.0021 0.001 0.0022
Brugia malayi hypothetical protein 0.0116 0.0259 0.2245
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0135 0.0308 0.0306
Loa Loa (eye worm) hypothetical protein 0.0031 0.0038 0.0095
Trichomonas vaginalis protein phosphatase 2A, caeel, putative 0.021 0.0504 0.9403
Echinococcus granulosus tyrosine protein phosphatase non receptor type 0.0423 0.1059 0.2753
Trichomonas vaginalis protein phosphatase, caeel, putative 0.021 0.0504 0.9403
Entamoeba histolytica Activator 1 140 kDa subunit, putative 0.0019 0.0007 0.000003189
Brugia malayi beta-lactamase 0.0071 0.0142 0.1223
Echinococcus multilocularis solute carrier family 22 0.0031 0.0038 0.0095
Plasmodium falciparum calcium-dependent protein kinase 1 0.0068 0.0134 0.0549
Trichomonas vaginalis protein phosphatase-7, putative 0.021 0.0504 0.9403
Brugia malayi Neurotransmitter-gated ion-channel transmembrane region family protein 0.0061 0.0115 0.0989
Schistosoma mansoni hypothetical protein 0.0048 0.0081 0.0079
Echinococcus granulosus tachykinin peptides receptor 99D 0.0428 0.1072 0.2787
Loa Loa (eye worm) hypothetical protein 0.0031 0.0038 0.0095
Echinococcus granulosus neuropeptides capa receptor 0.0116 0.0259 0.0671
Loa Loa (eye worm) abnormal chemotaxis protein 14 0.0044 0.0072 0.0182
Mycobacterium ulcerans sugar-transport integral membrane protein SugI 0.0031 0.0038 0.2288
Brugia malayi larval opioid receptor 0.0116 0.0259 0.2245
Leishmania major hypothetical protein, conserved 0.0031 0.0038 0.0196
Echinococcus multilocularis serine:threonine protein phosphatase 2A 56 kDa 0.002 0.001 0.002
Toxoplasma gondii histone lysine acetyltransferase GCN5-B 0.0048 0.0082 0.0505
Trichomonas vaginalis protein phosphatase, caeel, putative 0.021 0.0504 0.9403
Echinococcus granulosus allatostatin A receptor 0.0116 0.0259 0.0671
Plasmodium vivax aspartyl protease, putative 0.0191 0.0455 0.1878
Onchocerca volvulus 0.0031 0.0038 0.0162
Plasmodium falciparum hexose transporter 0.0222 0.0536 0.2213
Plasmodium falciparum LCCL domain-containing protein 0.0019 0.0007 0.0021
Echinococcus multilocularis rhodopsin orphan GPCR 0.0116 0.0259 0.0671
Echinococcus multilocularis g protein coupled receptor 0.0116 0.0259 0.0671
Echinococcus multilocularis neuropeptide receptor 0.0116 0.0259 0.0671
Brugia malayi Serine/threonine protein phosphatase PP1 isozyme 1, putative 0.0047 0.0079 0.067
Onchocerca volvulus 0.0116 0.0259 0.1312
Schistosoma mansoni myosin xvIII 0.0116 0.0259 0.0258
Toxoplasma gondii sugar transporter ST2 0.0031 0.0038 0.0229
Schistosoma mansoni lipoxygenase 0.0019 0.0007 0.0005
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0116 0.0259 0.0258
Schistosoma mansoni hypothetical protein 0.0103 0.0224 0.0223
Echinococcus multilocularis glycine receptor subunit alpha 1 0.0061 0.0115 0.0296
Brugia malayi hypothetical protein 0.0019 0.0007 0.0045
Echinococcus multilocularis allatostatin A receptor 0.0116 0.0259 0.0671
Echinococcus granulosus FTZ F1 alpha 0.0021 0.001 0.0022
Brugia malayi bifunctional aminoacyl-tRNA synthetase 0.0067 0.013 0.1121
Trypanosoma cruzi serine/threonine-protein phosphatase PP1, putative 0.0251 0.0609 0.3126
Echinococcus granulosus para nitrobenzyl esterase 0.0068 0.0135 0.0347
Loa Loa (eye worm) hypothetical protein 0.0054 0.0098 0.025
Schistosoma mansoni hypothetical protein 0.0678 0.1721 0.172
Echinococcus granulosus inositol monophosphatase 1 0.0045 0.0073 0.0185
Leishmania major glucose transporter, lmgt3 0.0069 0.0136 0.07
Toxoplasma gondii calcium-dependent protein kinase CDPK2A 0.0068 0.0134 0.0832
Leishmania major protein kinase, putative 0.002 0.001 0.0051
Loa Loa (eye worm) hypothetical protein 0.0116 0.0259 0.0671
Trichomonas vaginalis serine/threonine-protein phosphatase 2A 55 kDa regulatory subunit B gamma isoform, putative 0.0074 0.0149 0.2749
Trichomonas vaginalis protein phosphatase-7, putative 0.021 0.0504 0.9403
Loa Loa (eye worm) carboxylesterase 0.0068 0.0135 0.0347
Onchocerca volvulus 0.0068 0.0135 0.0665
Toxoplasma gondii histone lysine demethylase JMJD6a 0.0032 0.004 0.024
Echinococcus granulosus nicotinic acetylcholine receptor subunit type 0.0061 0.0115 0.0296
Brugia malayi GnHR receptor homolog 0.0116 0.0259 0.2245
Brugia malayi topoisomerase 0.0019 0.0007 0.0048
Echinococcus granulosus Cys loop ligand gated ion channel subunit 0.0028 0.003 0.0073
Echinococcus multilocularis neuropeptide Y receptor 0.0116 0.0259 0.0671
Onchocerca volvulus 0.0116 0.0259 0.1312
Onchocerca volvulus 0.0061 0.0115 0.0563
Loa Loa (eye worm) GABA receptor subunit 0.0033 0.0042 0.0105
Schistosoma mansoni hypothetical protein 0.0678 0.1721 0.172
Trichomonas vaginalis protein phosphatase 2A, regulatory subunit, putative 0.002 0.001 0.0146
Schistosoma mansoni Cys-loop ligand gated ion channel subunit 0.0061 0.0115 0.0114
Echinococcus multilocularis JmjC domain containing protein 4 0.0032 0.004 0.01
Loa Loa (eye worm) hypothetical protein 0.0028 0.003 0.0073
Trichomonas vaginalis sugar transporter, putative 0.0031 0.0038 0.0681
Trichomonas vaginalis conserved hypothetical protein 0.0037 0.0052 0.0948
Trichomonas vaginalis lysyl-tRNA synthetase, putative 0.0044 0.007 0.1278
Trichomonas vaginalis sugar transporter, putative 0.0031 0.0038 0.0681
Trypanosoma cruzi serine/threonine protein phosphatase catalytic subunit, putative 0.0051 0.009 0.0463
Loa Loa (eye worm) hypothetical protein 0.0019 0.0007 0.0013
Loa Loa (eye worm) hypothetical protein 0.021 0.0504 0.1308
Trichomonas vaginalis sugar transporter, putative 0.0031 0.0038 0.0681
Schistosoma mansoni BC026374 protein (S09 family) 0.0068 0.0135 0.0133
Echinococcus granulosus protein phosphatase pp2a regulatory subunit b 0.0074 0.0149 0.0382
Echinococcus multilocularis synaptic vesicle 2 protein 0.0031 0.0038 0.0095
Loa Loa (eye worm) hypothetical protein 0.0021 0.001 0.0022
Onchocerca volvulus Putative transporter 0.0031 0.0038 0.0162
Plasmodium vivax AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.0038 0.0057 0.0227
Brugia malayi Hypothetical glycine receptor like protein T20B12.9 in chromosome III 0.0061 0.0115 0.0989
Echinococcus multilocularis lysine specific demethylase 6a 0.0032 0.004 0.01
Onchocerca volvulus 0.0116 0.0259 0.1312
Toxoplasma gondii protein kinase, putative 0.0628 0.1592 1
Echinococcus granulosus neuropeptide Y receptor 0.0116 0.0259 0.0671
Echinococcus multilocularis gcn5proteinral control of amino acid synthesis 0.0164 0.0383 0.0993
Plasmodium falciparum plasmepsin I 0.0191 0.0455 0.1878
Brugia malayi hypothetical protein 0.0116 0.0259 0.2245
Brugia malayi Serotonin/octopamine receptor family protein 7 0.0116 0.0259 0.2245
Trypanosoma brucei calcium/calmodulin-dependent protein kinase, putative 0.0068 0.0134 0.0679
Echinococcus multilocularis nAChR subunit 0.0033 0.0042 0.0105
Trichomonas vaginalis sugar transporter, putative 0.0031 0.0038 0.0681
Trypanosoma cruzi serine/threonine-protein phosphatase PP1, putative 0.0765 0.1948 1
Brugia malayi Serotonin receptor 0.0116 0.0259 0.2245
Echinococcus multilocularis alpha 1A adrenergic receptor 0.0116 0.0259 0.0671
Loa Loa (eye worm) hypothetical protein 0.0028 0.003 0.0073
Toxoplasma gondii serine/threonine phosophatase PP1 0.0051 0.009 0.0556
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0116 0.0259 0.0258
Leishmania major protein kinase, putative 0.0068 0.0134 0.0688
Schistosoma mansoni jumonji domain containing protein 0.0032 0.004 0.0038
Schistosoma mansoni family S9 non-peptidase homologue (S09 family) 0.0405 0.1012 0.101
Onchocerca volvulus 0.0035 0.0048 0.0215
Onchocerca volvulus Huntingtin homolog 0.0148 0.0342 0.1741
Brugia malayi jmjC domain containing protein 0.012 0.0269 0.2327
Plasmodium vivax sugar transporter, putative 0.0031 0.0038 0.0151
Echinococcus granulosus peptide allatostatin:somatostatin 0.0116 0.0259 0.0671
Schistosoma mansoni hypothetical protein 0.0043 0.0068 0.0066
Echinococcus multilocularis protein patched 0.0044 0.0072 0.0182
Trichomonas vaginalis phosphoserine/threonine phosphatase, putative 0.021 0.0504 0.9403
Schistosoma mansoni protein phosphatase-1 0.0047 0.0079 0.0077
Plasmodium falciparum calcium-dependent protein kinase 5 0.0068 0.0134 0.0549
Loa Loa (eye worm) hypothetical protein 0.0033 0.0042 0.0105
Brugia malayi putative neuropeptide receptor 0.0116 0.0259 0.2245
Schistosoma mansoni Cys-loop ligand gated ion channel subunit 0.0061 0.0115 0.0114
Loa Loa (eye worm) hypothetical protein 0.0026 0.0025 0.0061
Entamoeba histolytica hypothetical protein 0.0106 0.0233 1
Schistosoma mansoni neuropeptide receptor 0.0116 0.0259 0.0258
Plasmodium falciparum plasmepsin IV 0.0191 0.0455 0.1878
Echinococcus granulosus g protein linked acetylcholine receptor gar 2a 0.0116 0.0259 0.0671
Trichomonas vaginalis protein phosphatase-7, putative 0.021 0.0504 0.9403
Onchocerca volvulus 0.021 0.0504 0.2581
Echinococcus granulosus nicotinic acetylcholine receptor beta 1 subunit 0.0061 0.0115 0.0296
Brugia malayi Cation transporter family protein 0.0061 0.0115 0.0989
Schistosoma mansoni steroid hormone receptor ad4bp 0.0021 0.001 0.0009
Onchocerca volvulus 0.0031 0.0038 0.0162
Schistosoma mansoni peptide (allatostatin)-like receptor 0.0116 0.0259 0.0258
Loa Loa (eye worm) hypothetical protein 0.0061 0.0115 0.0296
Trypanosoma brucei glucose transporter 1E 0.0069 0.0136 0.0691
Schistosoma mansoni nAChR subunit (ShAR1-beta-like) 0.0061 0.0115 0.0114
Echinococcus granulosus hypothetical protein 0.0116 0.0259 0.0671
Mycobacterium tuberculosis Possible conserved lipoprotein LpqK 0.0071 0.0142 0.0943
Loa Loa (eye worm) hypothetical protein 0.0071 0.0142 0.0366
Echinococcus granulosus serotonin receptor 0.0116 0.0259 0.0671
Plasmodium vivax multidomain scavenger receptor, putative 0.0019 0.0007 0.0021
Echinococcus granulosus lysine specific demethylase 5A 0.012 0.0269 0.0696
Brugia malayi hypothetical protein 0.0019 0.0007 0.0048
Schistosoma mansoni gliotactin 0.0068 0.0135 0.0133
Echinococcus granulosus serine:threonine protein phosphatase PP1 gamma 0.0051 0.009 0.023
Echinococcus multilocularis protein dispatched 1 0.005 0.0088 0.0224
Loa Loa (eye worm) hypothetical protein 0.0116 0.0259 0.0671
Echinococcus multilocularis nicotinic acetylcholine receptor subunit type 0.0028 0.003 0.0073
Loa Loa (eye worm) hypothetical protein 0.0116 0.0259 0.0671
Schistosoma mansoni hypothetical protein 0.0259 0.0631 0.0629
Echinococcus multilocularis Cys loop ligand gated ion channel subunit 0.0028 0.003 0.0073
Leishmania major myo-inositol-1(or 4)-monophosphatase 1, putative 0.0045 0.0073 0.0374
Echinococcus multilocularis rhodopsin orphan GPCR 0.0116 0.0259 0.0671
Loa Loa (eye worm) hypothetical protein 0.0061 0.0115 0.0296
Echinococcus granulosus expressed conserved protein 0.0097 0.0208 0.0538
Echinococcus multilocularis nibrin 0.0019 0.0007 0.0014
Trichomonas vaginalis protein phosphatase, caeel, putative 0.021 0.0504 0.9403
Loa Loa (eye worm) hypothetical protein 0.0033 0.0042 0.0105
Echinococcus multilocularis apoptotic protease activating factor 1 0.004 0.0062 0.0156
Brugia malayi Amyloid A4 extracellular domain containing protein 0.0323 0.0796 0.6924
Trichomonas vaginalis protein phosphatase PP2A regulatory subunit B, putative 0.0074 0.0149 0.2749
Echinococcus multilocularis Nuclear hormone receptor family member nhr 41 0.0021 0.001 0.0022
Echinococcus granulosus g protein coupled receptor 0.0116 0.0259 0.0671
Schistosoma mansoni phosphatidylserine receptor 0.0032 0.004 0.0038
Brugia malayi neuropeptide F receptor 0.0116 0.0259 0.2245
Echinococcus granulosus hepatocyte nuclear factor 4 alpha 0.0021 0.001 0.0022
Echinococcus multilocularis rhodopsin orphan GPCR 0.0116 0.0259 0.0671
Toxoplasma gondii aspartyl protease ASP3 0.0191 0.0455 0.2847
Schistosoma mansoni protein tyrosine phosphatase non-receptor type nt1 0.0423 0.1059 0.1057
Echinococcus granulosus JmjC domain containing protein 4 0.0032 0.004 0.01
Echinococcus multilocularis neuronal acetylcholine receptor subunit alpha 4 0.0061 0.0115 0.0296
Mycobacterium ulcerans beta-lactamase 0.0071 0.0142 1
Echinococcus granulosus cadherin EGF LAG seven pass G type receptor 0.0048 0.0081 0.0205
Trichomonas vaginalis Clan AA, family A1, cathepsin D-like aspartic peptidase 0.0191 0.0455 0.8483
Onchocerca volvulus 0.0031 0.0038 0.0162
Loa Loa (eye worm) aspartic protease BmAsp-2 0.0191 0.0455 0.118
Schistosoma mansoni aldehyde dehydrogenase 0.0069 0.0135 0.0134
Brugia malayi intermediate filament protein 0.0027 0.0027 0.0215
Echinococcus granulosus Basic leucine zipper bZIP transcription 0.0106 0.0233 0.0602
Brugia malayi aspartic protease BmAsp-2, identical 0.0191 0.0455 0.3946
Echinococcus multilocularis General substrate transporter 0.0191 0.0454 0.1179
Trichomonas vaginalis protein phosphatase-2B, putative 0.021 0.0504 0.9403
Brugia malayi jmjC domain containing protein 0.0032 0.004 0.0333
Trichomonas vaginalis sugar transporter, putative 0.0031 0.0038 0.0681
Echinococcus multilocularis serine:threonine protein phosphatase PP1 isozyme 0.0051 0.009 0.023
Wolbachia endosymbiont of Brugia malayi major facilitator superfamily permease 0.0031 0.0038 0.4706
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0021 0.001 0.0075
Schistosoma mansoni protein phosphatase 2a regulatory subunit 0.002 0.001 0.0008
Echinococcus granulosus solute carrier family 22 0.0031 0.0038 0.0095
Trichomonas vaginalis bsu-protein phosphatase, putative 0.0051 0.009 0.1656
Loa Loa (eye worm) nucleolar RNA-associated protein alpha 0.0259 0.0631 0.1638
Wolbachia endosymbiont of Brugia malayi fructose-1,6-bisphosphatase 0.0045 0.0073 1
Trichomonas vaginalis sugar transporter, putative 0.0031 0.0038 0.0681
Brugia malayi serine/threonine protein phosphatase 2A 0.0074 0.0149 0.1279
Brugia malayi hypothetical protein 0.0116 0.0259 0.2245
Mycobacterium leprae conserved hypothetical protein 0.0071 0.0142 1
Echinococcus multilocularis glutamyl tRNA synthetase cytoplasmic 0.0067 0.013 0.0335
Schistosoma mansoni acetylcholine receptor-related 0.0028 0.003 0.0028
Schistosoma mansoni retinoid-x-receptor (RXR) 0.0021 0.001 0.0009
Schistosoma mansoni neuropeptide F-like receptor 0.0116 0.0259 0.0258
Loa Loa (eye worm) hypothetical protein 0.0068 0.0135 0.0347
Loa Loa (eye worm) major facilitator superfamily transporter 0.0031 0.0038 0.0095
Entamoeba histolytica protein kinase, putative 0.0068 0.0134 0.5621
Trypanosoma cruzi ubiquitin carboxyl-terminal hydrolase, putative 0.0037 0.0052 0.0269
Loa Loa (eye worm) hypothetical protein 0.0068 0.0135 0.0347
Trichomonas vaginalis serine/threonine protein phosphatase, putative 0.021 0.0504 0.9403
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0116 0.0259 0.0258
Echinococcus granulosus arachidonate 5 lipoxygenase 0.0054 0.0097 0.0249
Loa Loa (eye worm) inositol-1 0.0045 0.0073 0.0185
Brugia malayi Pax transcription activation domain interacting protein 0.0019 0.0007 0.0048
Schistosoma mansoni muscarinic acetylcholine (GAR) receptor 0.0116 0.0259 0.0258
Echinococcus multilocularis protein phosphatase 2a regulatory subunit 0.002 0.001 0.002
Echinococcus granulosus serine:threonine protein phosphatase PP1 gamma 0.0051 0.009 0.023
Echinococcus multilocularis aldehyde dehydrogenase, mitochondrial 0.0069 0.0135 0.0348
Loa Loa (eye worm) hypoxia-induced factor 1 0.0147 0.034 0.0881
Echinococcus granulosus thyrotropin releasing hormone receptor 0.0116 0.0259 0.0671
Echinococcus granulosus pyroglutamylated rfamide peptide receptor 0.0116 0.0259 0.0671
Schistosoma mansoni thyrotropin-releasing hormone receptor 0.0116 0.0259 0.0258
Loa Loa (eye worm) hypothetical protein 0.0021 0.001 0.0022
Brugia malayi ATP dependent DNA ligase C terminal region family protein 0.0019 0.0007 0.0048
Trypanosoma brucei importin beta-1 subunit, putative 0.0024 0.002 0.0093
Onchocerca volvulus 0.0071 0.0142 0.0703
Trichomonas vaginalis protein phosphatase-7, caeel, putative 0.021 0.0504 0.9403
Trichomonas vaginalis conserved hypothetical protein 0.0031 0.0038 0.0681
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0071 0.0142 0.014
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0071 0.0142 0.014
Trichomonas vaginalis carboxylesterase domain containing protein, putative 0.0068 0.0135 0.2495
Loa Loa (eye worm) hypothetical protein 0.0068 0.0135 0.0347
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0021 0.001 0.0022
Mycobacterium ulcerans fusion of enoyl-CoA hydratase, EchA21 and lipase, LipE 0.0071 0.0142 1
Entamoeba histolytica exodeoxyribonuclease III, putative 0.0038 0.0057 0.2186
Plasmodium falciparum plasmepsin VIII, putative 0.0191 0.0455 0.1878
Schistosoma mansoni histamine-responsive GPCR (AAF21638) 0.0116 0.0259 0.0258
Trypanosoma cruzi prolyl-tRNA synthetase, putative 0.0078 0.0159 0.0817
Echinococcus multilocularis glycine receptor subunit alpha 1 0.0061 0.0115 0.0296
Echinococcus multilocularis lysyl tRNA synthetase 0.005 0.0086 0.0219
Trichomonas vaginalis serine/threonine protein phosphatase, putative 0.021 0.0504 0.9403
Echinococcus multilocularis acetylcholinesterase 0.0405 0.1012 0.263
Brugia malayi hypothetical protein 0.0028 0.003 0.0245
Echinococcus granulosus lysine specific demethylase 6a 0.0032 0.004 0.01
Echinococcus multilocularis glycine receptor subunit beta 0.0061 0.0115 0.0296
Trichomonas vaginalis protein phosphatase-7, putative 0.021 0.0504 0.9403
Loa Loa (eye worm) hypothetical protein 0.0061 0.0115 0.0296
Trypanosoma cruzi metacaspase, putative 0.0017 0.0002 0.0009
Trichomonas vaginalis glucose transporter, putative 0.0031 0.0038 0.0681
Trypanosoma cruzi hexose transporter, putative 0.0069 0.0136 0.07
Trypanosoma cruzi hexose transporter, putative 0.0069 0.0136 0.07
Trypanosoma brucei ubiquitin carboxyl-terminal hydrolase, putative 0.0037 0.0052 0.026
Onchocerca volvulus 0.0031 0.0038 0.0162
Brugia malayi hypothetical protein 0.0116 0.0259 0.2245
Brugia malayi hypothetical protein 0.0116 0.0259 0.2245
Loa Loa (eye worm) doublecortin family protein 0.0019 0.0007 0.0013
Loa Loa (eye worm) major facilitator superfamily transporter 0.0031 0.0038 0.0095
Schistosoma mansoni importin beta-1 0.0024 0.002 0.0018
Plasmodium falciparum mitogen-activated protein kinase 2 0.0359 0.0892 0.3692
Loa Loa (eye worm) nuclear Hormone Receptor family member 0.0021 0.001 0.0022
Onchocerca volvulus 0.0021 0.001 0.0018
Brugia malayi Serine/threonine protein phosphatase 2A, 56 kDa regulatory subunit,epsilon isoform 0.002 0.001 0.0068
Leishmania major serine/threonine protein phosphatase pp1(5.9), putative 0.0167 0.0392 0.2011
Echinococcus granulosus lipoxygenase domain containing protein 0.0019 0.0007 0.0013
Trichomonas vaginalis protein phosphatase-7, putative 0.021 0.0504 0.9403
Trypanosoma cruzi hexose transporter, putative 0.0069 0.0136 0.07
Trypanosoma brucei glucose transporter, putative 0.0069 0.0136 0.0691
Brugia malayi bHLH-PAS transcription factor 0.0035 0.0048 0.0406
Echinococcus multilocularis g protein coupled receptor 0.0116 0.0259 0.0671
Onchocerca volvulus 0.0758 0.1931 1
Loa Loa (eye worm) nuclear hormone receptor family member nhr-1 0.0021 0.001 0.0022
Echinococcus granulosus neuropeptide receptor 0.0116 0.0259 0.0671
Brugia malayi hypothetical protein 0.0116 0.0259 0.2245
Giardia lamblia Protein phosphatase 2A B regulatory subunit Wdb1 0.002 0.001 0.0162
Entamoeba histolytica myo-inositol monophosphatase, putative 0.0045 0.0073 0.291
Giardia lamblia Hexose transporter 0.0031 0.0038 0.2185
Echinococcus granulosus serine:threonine protein phosphatase 2A 56 kDa 0.002 0.001 0.002
Schistosoma mansoni protein kinase 0.0068 0.0134 0.0132
Schistosoma mansoni family S9 non-peptidase homologue (S09 family) 0.0068 0.0135 0.0133
Schistosoma mansoni hypothetical protein 0.0116 0.0259 0.0258
Echinococcus multilocularis G protein coupled receptor 139 0.0116 0.0259 0.0671
Trypanosoma cruzi sugar transporter, putative 0.0031 0.0038 0.0196
Brugia malayi delta isoform of regulatory subunit B56, protein phosphatase 2A 0.002 0.001 0.0068
Trichomonas vaginalis protein phosphatase-7, putative 0.021 0.0504 0.9403
Trichomonas vaginalis sugar transporter, putative 0.0031 0.0038 0.0681
Brugia malayi Serine/threonine protein phosphatase PP1 isozyme 1, putative 0.0047 0.0079 0.067
Echinococcus multilocularis ubiquitin carboxyl terminal hydrolase 8 0.0037 0.0052 0.0132
Brugia malayi Sugar transporter family protein 0.0031 0.0038 0.0317
Trypanosoma cruzi myo-inositol-1(or 4)-monophosphatase 1, putative 0.0045 0.0073 0.0374
Trichomonas vaginalis protein phosphatase, caeel, putative 0.0051 0.009 0.1656
Brugia malayi nuclear hormone receptor 0.0021 0.001 0.0075
Echinococcus multilocularis protein phosphatase pp2a regulatory subunit b 0.0074 0.0149 0.0382
Brugia malayi RNA, U transporter 1 0.0069 0.0136 0.1172
Loa Loa (eye worm) hypothetical protein 0.0058 0.0107 0.0273
Toxoplasma gondii LsmAD domain-containing protein 0.0101 0.022 0.1371
Schistosoma mansoni subfamily A1A unassigned peptidase (A01 family) 0.0191 0.0455 0.0453
Leishmania major hypothetical protein, conserved 0.0074 0.0149 0.0763
Echinococcus granulosus COUP TF:Svp nuclear hormone receptor 0.0021 0.001 0.0022
Loa Loa (eye worm) acetyltransferase 0.0164 0.0383 0.0993
Onchocerca volvulus 0.0031 0.0038 0.0162
Loa Loa (eye worm) ACC-1 protein 0.0061 0.0115 0.0296
Loa Loa (eye worm) hypothetical protein 0.0071 0.0142 0.0366
Loa Loa (eye worm) hypothetical protein 0.0116 0.0259 0.0671
Trypanosoma cruzi serine/threonine-protein phosphatase PP1 alpha 0.0251 0.0609 0.3126
Loa Loa (eye worm) carboxylesterase 0.0405 0.1012 0.263
Loa Loa (eye worm) LGC-31 protein 0.0061 0.0115 0.0296
Brugia malayi Dopamine receptor protein 1, putative (partial) 0.0116 0.0259 0.2245
Schistosoma mansoni nuclear hormone receptor nor-1/nor-2 0.0021 0.001 0.0009
Brugia malayi Latrophilin receptor protein 2 0.0048 0.0081 0.0687
Loa Loa (eye worm) hypothetical protein 0.0032 0.004 0.01
Echinococcus multilocularis solute carrier family 2, facilitated glucose 0.0222 0.0536 0.1391
Echinococcus multilocularis calcium dependent protein kinase 0.0064 0.0123 0.0316
Brugia malayi ORL1-like opioid receptor 0.0116 0.0259 0.2245
Onchocerca volvulus 0.0061 0.0115 0.0563
Schistosoma mansoni protein phosphatase-1 0.021 0.0504 0.0502
Schistosoma mansoni neuropeptide f receptor 76f 0.0116 0.0259 0.0258
Trypanosoma brucei glucose transporter, putative 0.0069 0.0136 0.0691
Brugia malayi DKFZp564C0469 protein 0.0019 0.0007 0.0048
Loa Loa (eye worm) hypothetical protein 0.0137 0.0312 0.0809
Schistosoma mansoni nAChR subunit 0.0061 0.0115 0.0114
Echinococcus granulosus histone acetyltransferase KAT2B 0.0159 0.0371 0.0962
Loa Loa (eye worm) G-protein coupled receptor 0.0116 0.0259 0.0671
Trichomonas vaginalis conserved hypothetical protein 0.0019 0.0007 0.0103
Schistosoma mansoni neuropeptide receptor 0.0116 0.0259 0.0258
Echinococcus granulosus importin subunit beta 1 0.0024 0.002 0.0047
Echinococcus multilocularis Ataxin 2, N terminal,domain containing protein 0.0045 0.0075 0.019
Echinococcus multilocularis jumonji domain containing 1A 0.0032 0.004 0.01
Brugia malayi Sugar transporter family protein 0.0031 0.0038 0.0317
Leishmania major glucose transporter, lmgt2 0.0069 0.0136 0.07
Schistosoma mansoni nuclear receptor 2DBD-gamma 0.0021 0.001 0.0009
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0116 0.0259 0.0258
Echinococcus granulosus tm gpcr rhodopsin 0.0116 0.0259 0.0671
Schistosoma mansoni ubiquitin-specific peptidase 8 (C19 family) 0.0037 0.0052 0.0051
Brugia malayi G-protein-linked acetylcholine receptor protein 2, putative 0.0116 0.0259 0.2245
Plasmodium vivax hypothetical protein, conserved 0.0071 0.0142 0.0582
Brugia malayi Niemann-Pick C1 protein precursor 0.0103 0.0225 0.1942
Echinococcus granulosus solute carrier family 2 facilitated glucose 0.0222 0.0536 0.1391
Trichomonas vaginalis sugar transporter, putative 0.0031 0.0038 0.0681
Brugia malayi Cam kinase protein 1 0.0068 0.0134 0.1152
Echinococcus granulosus neuropeptide receptor A26 0.0116 0.0259 0.0671
Mycobacterium ulcerans putative regulatory protein 0.0035 0.0048 0.3048
Trichomonas vaginalis sugar transporter, putative 0.0031 0.0038 0.0681
Onchocerca volvulus 0.0116 0.0259 0.1312
Schistosoma mansoni peptide (allatostatin/somatostatin)-like receptor 0.0116 0.0259 0.0258
Schistosoma mansoni coup transcription factor 0.0021 0.001 0.0009
Brugia malayi Tachykinin-like peptides receptor 99D 0.0116 0.0259 0.2245
Schistosoma mansoni protein phosphatase 2a regulatory subunit 0.002 0.001 0.0008
Leishmania major glucose transporter/membrane transporter D2, putative 0.0069 0.0136 0.07
Trichomonas vaginalis bsu-protein phosphatase, putative 0.0051 0.009 0.1656
Schistosoma mansoni inositol monophosphatase 0.0045 0.0073 0.0071
Brugia malayi major facilitator superfamily protein 0.0031 0.0038 0.0317
Trichomonas vaginalis sugar transporter, putative 0.0031 0.0038 0.0681
Plasmodium falciparum plasmepsin V 0.0191 0.0455 0.1878
Loa Loa (eye worm) acetylcholine receptor alpha subunit 0.0061 0.0115 0.0296
Echinococcus granulosus diuretic hormone 44 receptor GPRdih2 0.0048 0.0081 0.0205
Trypanosoma brucei protein phoshatase 1, putative 0.0765 0.1948 1
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0116 0.0259 0.0671
Loa Loa (eye worm) hypothetical protein 0.0061 0.0115 0.0296
Schistosoma mansoni hypothetical protein 0.0222 0.0536 0.0534
Brugia malayi aspartic protease BmAsp-1, identical 0.0191 0.0455 0.3946
Echinococcus multilocularis neuroligin 0.0068 0.0135 0.0347
Echinococcus multilocularis neuropeptide Y receptor 0.0116 0.0259 0.0671
Leishmania major myo-inositol/proton symporter (MIT) 0.0031 0.0038 0.0196
Loa Loa (eye worm) nuclear hormone receptor family member nhr-41 0.0021 0.001 0.0022
Plasmodium falciparum plasmepsin VI 0.0191 0.0455 0.1878
Plasmodium vivax mitogen-activated protein kinase 2, putative 0.0359 0.0892 0.3692
Loa Loa (eye worm) hypothetical protein 0.0028 0.003 0.0073
Loa Loa (eye worm) hypothetical protein 0.0191 0.0455 0.118
Echinococcus granulosus acetylcholine receptor subunit beta 1 0.0061 0.0115 0.0296
Schistosoma mansoni glucose transport protein 0.0222 0.0536 0.0534
Echinococcus multilocularis serotonin receptor 0.1492 0.384 1
Echinococcus granulosus cathepsin d lysosomal aspartyl protease 0.0191 0.0455 0.118
Brugia malayi Nuclear hormone receptor family member nhr-31 0.0021 0.001 0.0075
Echinococcus multilocularis calcium:calmodulin dependent protein kinase type 0.0068 0.0134 0.0344
Trypanosoma cruzi serine/threonine-protein phosphatase PP1 beta 0.0765 0.1948 1
Trichomonas vaginalis RNA polymerase II ctd phosphatase, putative 0.0019 0.0007 0.0103
Loa Loa (eye worm) hypothetical protein 0.0116 0.0259 0.0671
Schistosoma mansoni cellular tumor antigen P53 0.0048 0.0083 0.0081
Echinococcus multilocularis hepatocyte nuclear factor 4 alpha 0.0021 0.001 0.0022
Trichomonas vaginalis protein phosphatase 2A, caeel, putative 0.021 0.0504 0.9403
Brugia malayi hypothetical protein 0.0191 0.0455 0.3946
Loa Loa (eye worm) hypothetical protein 0.0071 0.0142 0.0366
Leishmania major importin beta-1 subunit, putative 0.002 0.0008 0.0041
Loa Loa (eye worm) hypothetical protein 0.0116 0.0259 0.0671
Echinococcus multilocularis muscleblind protein 0.0156 0.0363 0.0941
Trypanosoma cruzi metacaspase 5, putative 0.0017 0.0002 0.0009
Onchocerca volvulus Cell death protein 3 homolog 0.0058 0.0107 0.0518
Echinococcus multilocularis Polycystic kidney disease protein 0.0019 0.0007 0.0013
Trypanosoma brucei serine threonine-protein phosphatase PP1, putative 0.0251 0.0609 0.312
Trichomonas vaginalis bsu-protein phosphatase, putative 0.021 0.0504 0.9403
Echinococcus granulosus BC026374 protein S09 family 0.0068 0.0135 0.0347
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0037 0.0052 0.0948
Schistosoma mansoni subfamily A1A unassigned peptidase (A01 family) 0.0191 0.0455 0.0453
Brugia malayi Melatonin receptor type 1A 0.0116 0.0259 0.2245
Trichomonas vaginalis sugar transporter, putative 0.0031 0.0038 0.0681
Schistosoma mansoni polycystin 1-related 0.0019 0.0007 0.0005
Entamoeba histolytica serine/threonine protein phosphatase PP1, putative 0.0047 0.0079 0.317
Schistosoma mansoni acetylcholine receptor subunit beta 0.0028 0.003 0.0028
Plasmodium vivax plasmepsin IV, putative 0.0191 0.0455 0.1878
Onchocerca volvulus 0.0116 0.0259 0.1312
Onchocerca volvulus 0.0116 0.0259 0.1312
Onchocerca volvulus 0.0031 0.0038 0.0162
Toxoplasma gondii aspartyl protease ASP1 0.0191 0.0455 0.2847
Onchocerca volvulus 0.0458 0.1149 0.5937
Echinococcus multilocularis neuropeptide FF receptor 2 0.0116 0.0259 0.0671
Echinococcus multilocularis sex peptide receptor 0.0116 0.0259 0.0671
Schistosoma mansoni subfamily A1A unassigned peptidase (A01 family) 0.0191 0.0455 0.0453
Schistosoma mansoni nuclear transcription factor X-box binding 1 (nfx1) 0.0031 0.0038 0.0036
Echinococcus multilocularis pyroglutamylated rfamide peptide receptor 0.0116 0.0259 0.0671
Loa Loa (eye worm) protein-tyrosine phosphatase 0.0423 0.1059 0.2753
Schistosoma mansoni ap endonuclease 0.0038 0.0057 0.0055
Loa Loa (eye worm) hypothetical protein 0.0033 0.0042 0.0105
Plasmodium falciparum calcium-dependent protein kinase 3 0.0068 0.0134 0.0549
Trypanosoma brucei protein phosphatase 2A regulatory subunit, putative 0.0074 0.0149 0.0754
Schistosoma mansoni hypothetical protein 0.0043 0.0068 0.0066
Plasmodium falciparum histone acetyltransferase GCN5 0.0044 0.0072 0.029
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0116 0.0259 0.0671
Schistosoma mansoni glucose transport protein 0.0222 0.0536 0.0534
Loa Loa (eye worm) hypothetical protein 0.0116 0.0259 0.0671
Echinococcus multilocularis importin subunit beta 1 0.0024 0.002 0.0047
Mycobacterium ulcerans aldehyde dehydrogenase 0.0069 0.0135 0.9496
Trichomonas vaginalis protein phosphatase-1, putative 0.021 0.0504 0.9403
Onchocerca volvulus 0.0031 0.0038 0.0162
Echinococcus multilocularis solute carrier family 22 0.0031 0.0038 0.0095
Trypanosoma brucei glucose transporter, putative 0.0069 0.0136 0.0691
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0116 0.0259 0.0258
Trichomonas vaginalis protein phosphatase-1, putative 0.021 0.0504 0.9403
Toxoplasma gondii aldehyde dehydrogenase 0.0069 0.0135 0.084
Trichomonas vaginalis bsu-protein phosphatase, putative 0.021 0.0504 0.9403
Schistosoma mansoni histamine h1 receptor 0.0116 0.0259 0.0258
Onchocerca volvulus 0.0061 0.0115 0.0563
Trichomonas vaginalis protein phosphatase-1, putative 0.0051 0.009 0.1656
Trichomonas vaginalis serine/threonine protein phosphatase, putative 0.0047 0.0079 0.1441
Loa Loa (eye worm) carboxylesterase 0.0068 0.0135 0.0347
Schistosoma mansoni amine GPCR 0.0116 0.0259 0.0258
Trichomonas vaginalis phosphoserine/threonine phosphatase, putative 0.021 0.0504 0.9403
Loa Loa (eye worm) hypothetical protein 0.0068 0.0134 0.0345
Schistosoma mansoni biogenic amine receptor 0.0116 0.0259 0.0258
Trichomonas vaginalis protein phosphatase-1, putative 0.0047 0.0079 0.1441
Leishmania major apurinic/apyrimidinic endonuclease-redox protein 0.0038 0.0057 0.029
Brugia malayi Neurotransmitter-gated ion-channel ligand binding domain containing protein 0.0061 0.0115 0.0989
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0135 0.0308 0.0797
Schistosoma mansoni neuropeptide receptor 0.0116 0.0259 0.0258
Brugia malayi beta-lactamase family protein 0.0071 0.0142 0.1223
Loa Loa (eye worm) hypothetical protein 0.0116 0.0259 0.0671
Schistosoma mansoni memapsin-2 (A01 family) 0.2476 0.6404 0.6403
Brugia malayi N-terminal motif family protein 0.0178 0.042 0.3641
Trypanosoma cruzi protein phosphatase 2A regulatory subunit, putative 0.0074 0.0149 0.0763
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0135 0.0308 0.0797
Echinococcus multilocularis para nitrobenzyl esterase 0.0068 0.0135 0.0347
Trichomonas vaginalis conserved hypothetical protein 0.0019 0.0007 0.0103
Loa Loa (eye worm) hypothetical protein 0.0116 0.0259 0.0671
Loa Loa (eye worm) beta-LACTamase domain containing family member 0.0071 0.0142 0.0366
Trypanosoma cruzi PAB1-binding protein , putative 0.0101 0.022 0.1129
Schistosoma mansoni sugar transporter 0.0031 0.0038 0.0036
Schistosoma mansoni biogenic amine (5HT) receptor 0.1492 0.384 0.3839
Trypanosoma cruzi hypothetical protein, conserved 0.0071 0.0142 0.073
Loa Loa (eye worm) hypothetical protein 0.0021 0.001 0.0022
Trichomonas vaginalis myo-inositol transporter, putative 0.0031 0.0038 0.0681
Echinococcus multilocularis Cys loop ligand gated ion channel subunit 0.0061 0.0115 0.0296
Echinococcus granulosus solute carrier family 2 facilitated glucose 0.0222 0.0536 0.1391
Loa Loa (eye worm) hypothetical protein 0.0028 0.003 0.0073
Onchocerca volvulus 0.0033 0.0042 0.0183
Echinococcus granulosus dro:myosuppressin receptor 0.0116 0.0259 0.0671
Leishmania major serine/threonine-protein phosphatase PP1, putative 0.0047 0.0079 0.0404
Loa Loa (eye worm) hypothetical protein 0.0103 0.0225 0.058
Giardia lamblia Histone acetyltransferase GCN5 0.0044 0.0072 0.456
Trypanosoma brucei importin beta-1 subunit, putative 0.0024 0.002 0.0093
Echinococcus multilocularis family S9 non peptidase ue (S09 family) 0.0068 0.0135 0.0347
Echinococcus granulosus neuropeptide receptor 0.0116 0.0259 0.0671
Brugia malayi Nuclear hormone receptor family member nhr-14 0.0021 0.001 0.0075
Trypanosoma cruzi hypothetical protein, conserved 0.0074 0.0149 0.0763
Brugia malayi gamma-aminobutyric-acid receptor beta subunit precursor 0.0061 0.0115 0.0989
Schistosoma mansoni amine GPCR 0.0116 0.0259 0.0258
Loa Loa (eye worm) hypothetical protein 0.0116 0.0259 0.0671
Schistosoma mansoni lamin 0.0027 0.0027 0.0025
Loa Loa (eye worm) hypothetical protein 0.0148 0.0342 0.0886
Schistosoma mansoni protein phosphatase 2C 0.0032 0.004 0.0038
Trichomonas vaginalis sugar transporter, putative 0.0031 0.0038 0.0681
Loa Loa (eye worm) hypothetical protein 0.0061 0.0115 0.0296
Onchocerca volvulus 0.0191 0.0455 0.2326
Echinococcus granulosus Ataxin 2 N terminaldomain containing protein 0.0045 0.0075 0.019
Trypanosoma brucei PAB1-binding protein , putative 0.0101 0.022 0.112
Trichomonas vaginalis protein phsophatase-2A, putative 0.021 0.0504 0.9403
Schistosoma mansoni family S9 non-peptidase homologue (S09 family) 0.0068 0.0135 0.0133
Loa Loa (eye worm) hypothetical protein 0.0028 0.003 0.0073
Loa Loa (eye worm) hypothetical protein 0.0116 0.0259 0.0671
Schistosoma mansoni growth hormone secretagogue receptor 0.0116 0.0259 0.0258
Leishmania major metacaspase, putative 0.0017 0.0002 0.0009
Toxoplasma gondii inositol(myo)-1(or 4)-monophosphatase 2, putative 0.0045 0.0073 0.0447
Toxoplasma gondii facilitative glucose transporter GT1 0.0222 0.0536 0.3356
Brugia malayi acetylcholine receptor, alpha-type subunit unc-38 precursor 0.0061 0.0115 0.0989
Echinococcus granulosus neuronal acetylcholine receptor subunit alpha 4 0.0061 0.0115 0.0296
Trichomonas vaginalis lysyl-tRNA synthetase, putative 0.005 0.0086 0.1577
Loa Loa (eye worm) hypothetical protein 0.0061 0.0115 0.0296
Mycobacterium tuberculosis Probable esterase/lipase LipP 0.0071 0.0142 0.0943
Leishmania major protein phosphatase 2A regulatory subunit, putative 0.0074 0.0149 0.0763
Echinococcus multilocularis atpase aaa+ type core atpase aaa type core 0.0806 0.2054 0.5346
Schistosoma mansoni Cys-loop ligand gated ion channel subunit 0.0061 0.0115 0.0114
Loa Loa (eye worm) hypothetical protein 0.0116 0.0259 0.0671
Loa Loa (eye worm) hypothetical protein 0.0178 0.042 0.1088
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0021 0.001 0.0075
Trichomonas vaginalis sugar transporter, putative 0.0069 0.0136 0.2519
Loa Loa (eye worm) hypothetical protein 0.0028 0.003 0.0073
Brugia malayi Dopamine receptor 0.0116 0.0259 0.2245
Echinococcus granulosus General substrate transporter 0.0191 0.0454 0.1179
Brugia malayi Serotonin receptor 0.0116 0.0259 0.2245
Plasmodium falciparum JmjC domain-containing protein, putative 0.0032 0.004 0.0158
Brugia malayi Carboxylesterase family protein 0.0068 0.0135 0.1161
Echinococcus multilocularis protein phosphatase 1 catalytic subunit 0.0051 0.009 0.023
Loa Loa (eye worm) hypothetical protein 0.0156 0.0363 0.0941
Schistosoma mansoni hypothetical protein 0.0048 0.0081 0.0079
Echinococcus granulosus beta LACTamase domain containing family member 0.0071 0.0142 0.0366
Trichomonas vaginalis protein phsophatase-2A, putative 0.021 0.0504 0.9403
Mycobacterium tuberculosis Conserved protein 0.0071 0.0142 0.0943
Brugia malayi hypothetical protein 0.016 0.0372 0.3227
Trichomonas vaginalis conserved hypothetical protein 0.0019 0.0007 0.0103
Onchocerca volvulus 0.0071 0.0142 0.0703
Schistosoma mansoni glutamyl-tRNA synthetase cytoplasmic (glutamate--tRNA ligase) (glurs) 0.0067 0.013 0.0129
Brugia malayi Ser/Thr protein phosphatase family protein 0.021 0.0504 0.4374
Loa Loa (eye worm) TYRA-2 protein 0.0116 0.0259 0.0671
Brugia malayi Dopamine receptor protein 2 0.0116 0.0259 0.2245
Echinococcus granulosus lipoxygenase domain containing protein 0.0019 0.0007 0.0013
Toxoplasma gondii lysine-tRNA ligase 0.005 0.0086 0.0529
Treponema pallidum prolyl-tRNA synthetase 0.0024 0.0018 0.2196
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0021 0.001 0.0022
Loa Loa (eye worm) neuropeptide F receptor 0.0116 0.0259 0.0671
Echinococcus granulosus solute carrier family 2 facilitated glucose 0.0222 0.0536 0.1391
Brugia malayi AKH receptor 0.0116 0.0259 0.2245
Entamoeba histolytica hypothetical protein 0.0106 0.0233 1
Trichomonas vaginalis protein phosphatase-5, putative 0.021 0.0504 0.9403
Trypanosoma brucei myo-inositol/proton symporter (MIT) 0.0031 0.0038 0.0187
Plasmodium vivax aspartyl protease, putative 0.0191 0.0455 0.1878
Onchocerca volvulus 0.0028 0.003 0.0119
Echinococcus granulosus intermediate filament protein 0.0027 0.0027 0.0064
Loa Loa (eye worm) hypothetical protein 0.0061 0.0115 0.0296
Brugia malayi GTP-binding regulatory protein Gs alpha-S chain, putative 0.0135 0.0308 0.2665
Leishmania major serine/threonine protein phosphatase catalytic subunit, putative 0.0051 0.009 0.0463
Echinococcus granulosus replication factor c subunit 1 0.0019 0.0007 0.0014
Echinococcus multilocularis serine:threonine protein phosphatase 2A 56 kDa 0.002 0.001 0.002
Onchocerca volvulus 0.0061 0.0115 0.0563
Trypanosoma brucei THT1 - hexose transporter, putative 0.0069 0.0136 0.0691
Brugia malayi hypothetical protein 0.0028 0.003 0.0245
Trichomonas vaginalis glucose transporter, putative 0.0069 0.0136 0.2519
Schistosoma mansoni jumonji domain containing protein 0.012 0.0269 0.0267
Loa Loa (eye worm) hypothetical protein 0.0116 0.0259 0.0671
Echinococcus granulosus glutamyl tRNA synthetase cytoplasmic 0.0067 0.013 0.0335
Schistosoma mansoni peptide (FMRFamide/neurokinin-3)-like receptor 0.0116 0.0259 0.0258
Echinococcus granulosus neuropeptide s receptor 0.0116 0.0259 0.0671
Entamoeba histolytica protein phosphatase regulatory subunit, putative 0.0074 0.0149 0.6267
Brugia malayi hypothetical protein 0.0116 0.0259 0.2245
Schistosoma mansoni DNA ligase IV 0.0019 0.0007 0.0005
Plasmodium falciparum calcium-dependent protein kinase 2 0.0068 0.0134 0.0549
Brugia malayi glutamate-gated chloride channel alpha3A subunit, putative 0.0033 0.0042 0.0352
Echinococcus multilocularis Jumonji, AT rich interactive domain 1B 0.0032 0.004 0.01
Loa Loa (eye worm) hypothetical protein 0.0116 0.0259 0.0671
Plasmodium falciparum serine/threonine protein phosphatase PP1 0.0051 0.009 0.0367
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0021 0.001 0.0022
Onchocerca volvulus 0.0031 0.0038 0.0162
Trypanosoma brucei protein phosphatase 1 0.0167 0.0392 0.2004
Echinococcus multilocularis microtubule associated protein 2 0.0728 0.1851 0.4817
Trichomonas vaginalis bsu-protein phosphatase, putative 0.0204 0.0487 0.9089
Echinococcus multilocularis thyrotropin releasing hormone receptor 0.0116 0.0259 0.0671
Loa Loa (eye worm) acetylcholine receptor protein 0.0028 0.003 0.0073
Echinococcus multilocularis calcium:calmodulin dependent protein kinase type 0.0068 0.0134 0.0344
Loa Loa (eye worm) latrophilin receptor protein 2 0.0048 0.0081 0.0205
Trichomonas vaginalis conserved hypothetical protein 0.0044 0.0072 0.131
Toxoplasma gondii aspartyl proteinase (eimepsin), putative 0.0191 0.0455 0.2847
Onchocerca volvulus 0.0068 0.0135 0.0665
Mycobacterium tuberculosis Lysyl-tRNA synthetase 1 LysS (lysine--tRNA ligase 1) (LysRS 1) (lysine translase) 0.0042 0.0066 0.0257
Schistosoma mansoni retinoic acid receptor RXR 0.0021 0.001 0.0009
Trypanosoma brucei glucose transporter, putative 0.0069 0.0136 0.0691
Loa Loa (eye worm) hypothetical protein 0.0028 0.003 0.0073
Echinococcus granulosus acetylcholinesterase 0.0405 0.1012 0.263
Loa Loa (eye worm) hypothetical protein 0.0116 0.0259 0.0671
Toxoplasma gondii protein phosphatase 2a regulatory b subunit (b56 family) protein 0.002 0.001 0.0049
Plasmodium falciparum plasmepsin IX 0.0191 0.0455 0.1878
Giardia lamblia Ubiquitin carboxyl-terminal hydrolase 4 0.0037 0.0052 0.3193
Loa Loa (eye worm) hypothetical protein 0.0116 0.0259 0.0671
Trichomonas vaginalis protein phosphatase-1, putative 0.021 0.0504 0.9403
Loa Loa (eye worm) hypothetical protein 0.0037 0.0052 0.0132
Brugia malayi lysyl-tRNA synthetase 0.005 0.0086 0.0733
Mycobacterium tuberculosis POSSIBLE PARA-NITROBENZYL ESTERASE (FRAGMENT) 0.0068 0.0135 0.0878
Loa Loa (eye worm) hypothetical protein 0.0061 0.0115 0.0296
Onchocerca volvulus Neuropeptide F receptor homolog 0.0116 0.0259 0.1312
Plasmodium vivax hexose transporter 0.0222 0.0536 0.2213
Echinococcus multilocularis ubiquitin specific protease 41 0.0037 0.0052 0.0132
Entamoeba histolytica Niemann-Pick C1 protein, putative 0.0103 0.0225 0.964
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0116 0.0259 0.0258
Leishmania major serine/threonine-protein phosphatase PP1, putative 0.0047 0.0079 0.0404
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0116 0.0259 0.0258
Loa Loa (eye worm) hypothetical protein 0.0067 0.013 0.0335
Brugia malayi Serine/threonine protein phosphatase PP1-gamma catalytic subunit 0.0047 0.0079 0.067
Plasmodium vivax proline--tRNA ligase, putative 0.0078 0.0159 0.0653
Brugia malayi Carboxylesterase family protein 0.0068 0.0135 0.1161
Echinococcus multilocularis nicotinic acetylcholine receptor a11 subunit 0.0061 0.0115 0.0296
Brugia malayi acetyltransferase, GNAT family protein 0.0164 0.0383 0.3323
Trypanosoma cruzi hypothetical protein, conserved 0.0071 0.0142 0.073
Echinococcus granulosus acetylcholinesterase 0.0405 0.1012 0.263
Loa Loa (eye worm) hypothetical protein 0.0148 0.0342 0.0886
Schistosoma mansoni nAChR subunit (ShAR1-alpha-like) 0.0061 0.0115 0.0114
Loa Loa (eye worm) hypothetical protein 0.0033 0.0042 0.0105
Echinococcus multilocularis rhodopsin orphan GPCR 0.0116 0.0259 0.0671
Trichomonas vaginalis sugar transporter, putative 0.0031 0.0038 0.0681
Schistosoma mansoni neurotransmitter gated ion channel 0.0033 0.0042 0.004
Brugia malayi Neurotransmitter-gated ion-channel transmembrane region family protein 0.0061 0.0115 0.0989
Schistosoma mansoni amine GPCR 0.0116 0.0259 0.0258
Trypanosoma brucei inositol-1(or 4)-monophosphatase 1, putative 0.0045 0.0073 0.0365
Schistosoma mansoni protein phosphatase-1 0.0051 0.009 0.0088
Trichomonas vaginalis protein phosphatase-1, putative 0.021 0.0504 0.9403
Schistosoma mansoni neurotransmitter gated ion channel 0.0028 0.003 0.0028
Giardia lamblia Protein phosphatase PP2A regulatory subunit B 0.0074 0.0149 1
Onchocerca volvulus 0.0019 0.0007 0.0002
Onchocerca volvulus 0.0116 0.0259 0.1312
Schistosoma mansoni Cys-loop ligand gated ion channel subunit 0.0033 0.0042 0.004
Giardia lamblia Sugar-proton symporter 0.0031 0.0038 0.2185
Trichomonas vaginalis sugar transporter, putative 0.0031 0.0038 0.0681
Trichomonas vaginalis protein phosphatase-5, putative 0.0047 0.0079 0.1441
Brugia malayi Serine/threonine protein phosphatase F56C9.1 in chromosomeIII 0.0051 0.009 0.077
Schistosoma mansoni hypothetical protein 0.0106 0.0233 0.0231
Brugia malayi follicle stimulating hormone receptor 0.031 0.0763 0.6633
Trichomonas vaginalis protein phosphatase pp2a regulatory subunit B, putative 0.0074 0.0149 0.2749
Loa Loa (eye worm) hypothetical protein 0.0048 0.0083 0.0211
Echinococcus multilocularis lamin 0.0027 0.0027 0.0064
Echinococcus multilocularis ecdysone induced protein 78C 0.0021 0.001 0.0022
Leishmania major ubiquitin hydrolase, putative,cysteine peptidase, Clan CA, family C19, putative 0.0037 0.0052 0.0269
Brugia malayi Neurotransmitter-gated ion-channel ligand binding domain containing protein 0.0061 0.0115 0.0989
Schistosoma mansoni subfamily A1A unassigned peptidase (A01 family) 0.0191 0.0455 0.0453
Mycobacterium ulcerans hypothetical protein 0.0071 0.0142 1
Echinococcus granulosus neuropeptides capa receptor 0.0116 0.0259 0.0671
Loa Loa (eye worm) glutamate-gated chloride channel alpha3A subunit 0.0061 0.0115 0.0296
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0135 0.0308 0.0797
Leishmania major lysyl-tRNA synthetase, putative 0.005 0.0086 0.0441
Brugia malayi hypothetical protein 0.0031 0.0038 0.0317
Trypanosoma brucei bifunctional aminoacyl-tRNA synthetase, putative 0.0078 0.0159 0.0809
Echinococcus multilocularis replication factor c subunit 1 0.0019 0.0007 0.0014
Loa Loa (eye worm) gonadotropin-releasing hormone receptor 2 0.0116 0.0259 0.0671
Mycobacterium ulcerans lysyl-tRNA synthetase 0.005 0.0086 0.5832
Loa Loa (eye worm) intermediate filament tail domain-containing protein 0.0027 0.0027 0.0064
Echinococcus multilocularis GPCR, family 2 0.0048 0.0081 0.0205
Trichomonas vaginalis protein phosphatase, caeel, putative 0.0047 0.0079 0.1441
Brugia malayi sulfakinin receptor protein 0.0116 0.0259 0.2245
Toxoplasma gondii aspartyl protease 0.0191 0.0455 0.2847
Loa Loa (eye worm) hypothetical protein 0.0103 0.0224 0.058
Echinococcus granulosus g-protein coupled receptor 0.0116 0.0259 0.0671
Echinococcus granulosus protein phosphatase 2a regulatory subunit 0.002 0.001 0.002
Plasmodium falciparum AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.0038 0.0057 0.0227
Loa Loa (eye worm) beta-lactamase 0.0071 0.0142 0.0366
Onchocerca volvulus 0.0116 0.0259 0.1312
Loa Loa (eye worm) hypothetical protein 0.0031 0.0038 0.0095
Loa Loa (eye worm) nuclear hormone receptor family member nhr-31 0.0021 0.001 0.0022
Loa Loa (eye worm) hypothetical protein 0.0116 0.0259 0.0671
Trichomonas vaginalis CAMK family protein kinase 0.0068 0.0134 0.2477
Schistosoma mansoni thyroid hormone receptor 0.0021 0.001 0.0009
Plasmodium falciparum lysine--tRNA ligase 0.005 0.0086 0.0349
Toxoplasma gondii HEAT repeat-containing protein 0.0024 0.002 0.0114
Echinococcus multilocularis FTZ F1 alpha 0.0021 0.001 0.0022
Loa Loa (eye worm) hypothetical protein 0.0031 0.0038 0.0095
Trichomonas vaginalis myo inositol monophosphatase, putative 0.0045 0.0073 0.1332
Trichomonas vaginalis replication factor C large subunit, putative 0.0019 0.0007 0.0103
Schistosoma mansoni glucose transporter 0.0031 0.0038 0.0036
Wolbachia endosymbiont of Brugia malayi exonuclease III 0.0038 0.0057 0.7513
Echinococcus granulosus g protein coupled receptor 0.0116 0.0259 0.0671
Brugia malayi hypothetical protein 0.0101 0.022 0.19
Trypanosoma brucei BRCA1 C Terminus (BRCT) domain containing protein, putative 0.0019 0.0007 0.0028
Loa Loa (eye worm) hypothetical protein 0.1492 0.384 1
Mycobacterium ulcerans prolyl-tRNA synthetase 0.0024 0.0018 0.0802
Loa Loa (eye worm) hypothetical protein 0.0032 0.004 0.01
Loa Loa (eye worm) calcium/calmodulin-dependent protein kinase ID 0.0068 0.0134 0.0344
Schistosoma mansoni thyroid hormone receptor 0.0021 0.001 0.0009
Toxoplasma gondii cell-cycle-associated protein kinase MAPK, putative 0.0359 0.0892 0.5598
Entamoeba histolytica prolyl-tRNA synthetase, putative 0.0067 0.013 0.5462
Echinococcus multilocularis Niemann Pick C1 protein 0.0103 0.0225 0.058
Echinococcus multilocularis serine:threonine protein phosphatase PP1 gamma 0.0051 0.009 0.023
Loa Loa (eye worm) hypothetical protein 0.0031 0.0038 0.0095
Echinococcus granulosus DNA apurinic or apyrimidinic site lyase 0.0038 0.0057 0.0143
Brugia malayi Carboxylesterase family protein 0.0068 0.0135 0.1161
Trichomonas vaginalis inositol monophosphatase, putative 0.0045 0.0073 0.1332
Onchocerca volvulus 0.0116 0.0259 0.1312
Onchocerca volvulus 0.021 0.0504 0.2581
Plasmodium vivax aspartyl protease, putative 0.0191 0.0455 0.1878
Echinococcus multilocularis dro:myosuppressin receptor 0.0116 0.0259 0.0671
Trypanosoma cruzi BRCA1 C Terminus (BRCT) domain containing protein, putative 0.0019 0.0007 0.0037
Onchocerca volvulus Protein ultraspiracle homolog 0.0021 0.001 0.0018
Echinococcus granulosus rhodopsin orphan GPCR 0.0116 0.0259 0.0671
Brugia malayi Carboxylesterase family protein 0.0068 0.0135 0.1161
Brugia malayi Calcium/calmodulin-dependent protein kinase type II alpha chain 0.0068 0.0134 0.1152
Loa Loa (eye worm) bifunctional aminoacyl-tRNA synthetase 0.0027 0.0028 0.0068
Schistosoma mansoni jumonji/arid domain-containing protein 0.012 0.0269 0.0267
Loa Loa (eye worm) hypothetical protein 0.021 0.0504 0.1308
Echinococcus granulosus carboxylesterase 5A 0.0405 0.1012 0.263
Loa Loa (eye worm) hypothetical protein 0.0116 0.0259 0.0671
Onchocerca volvulus 0.0061 0.0115 0.0563
Trichomonas vaginalis sugar transporter, putative 0.0031 0.0038 0.0681
Onchocerca volvulus 0.0116 0.0259 0.1312
Brugia malayi hypothetical protein 0.0068 0.0135 0.1161
Brugia malayi Major Facilitator Superfamily protein 0.0031 0.0038 0.0317
Loa Loa (eye worm) hypothetical protein 0.0116 0.0259 0.0671
Schistosoma mansoni hypothetical protein 0.0048 0.0081 0.0079
Brugia malayi major facilitator superfamily protein 0.0031 0.0038 0.0317
Schistosoma mansoni rab6-interacting 0.0019 0.0007 0.0005
Brugia malayi jmjC domain containing protein 0.0032 0.004 0.0333
Trypanosoma brucei THT1 - hexose transporter, putative 0.0069 0.0136 0.0691
Mycobacterium tuberculosis Possible penicillin-binding protein 0.0455 0.1141 1
Loa Loa (eye worm) hypothetical protein 0.0031 0.0038 0.0095
Echinococcus multilocularis lipoxygenase domain containing protein 0.0019 0.0007 0.0013
Schistosoma mansoni topbp1 0.0019 0.0007 0.0005
Plasmodium vivax histone acetyltransferase GCN5, putative 0.0048 0.0082 0.0333
Onchocerca volvulus 0.0191 0.0455 0.2326
Loa Loa (eye worm) hypothetical protein 0.021 0.0504 0.1308
Loa Loa (eye worm) hypothetical protein 0.0061 0.0115 0.0296
Toxoplasma gondii transporter, major facilitator family protein 0.0031 0.0038 0.0229
Schistosoma mansoni peptide (FMRFamide/somatostatin)-like receptor 0.0116 0.0259 0.0258
Schistosoma mansoni protein phosphatase-1 0.0051 0.009 0.0088
Onchocerca volvulus Steroid hormone receptor family member cnr14 homolog 0.0021 0.001 0.0018
Brugia malayi G protein-coupled receptor 0.0116 0.0259 0.2245
Onchocerca volvulus 0.0031 0.0038 0.0162
Loa Loa (eye worm) hypothetical protein 0.0033 0.0042 0.0105
Echinococcus granulosus Sugar transporter ERD6 protein 0.0031 0.0038 0.0095
Schistosoma mansoni biogenic amine receptor 0.0116 0.0259 0.0258
Brugia malayi acetylcholine receptor protein, alpha-like chain, putative 0.0061 0.0115 0.0989
Trichomonas vaginalis protein phosphatase-5, putative 0.021 0.0504 0.9403
Trypanosoma cruzi metacaspase 5, putative 0.0017 0.0002 0.0009
Trichomonas vaginalis serine/threonine protein phosphatase, putative 0.021 0.0504 0.9403
Brugia malayi Acetylcholine receptor protein, alpha-like chain 1 precursor 0.0028 0.003 0.0245
Plasmodium vivax lysine--tRNA ligase, putative 0.005 0.0086 0.0349
Giardia lamblia Lysyl-tRNA synthetase 0.005 0.0086 0.5569
Echinococcus granulosus glycine receptor subunit alpha 1 0.0061 0.0115 0.0296
Brugia malayi Ubiquitin carboxyl-terminal hydrolase family protein 0.0037 0.0052 0.0441
Plasmodium falciparum plasmepsin X 0.0191 0.0455 0.1878
Echinococcus granulosus sex peptide receptor 0.0116 0.0259 0.0671
Schistosoma mansoni biogenic amine (5HT) receptor 0.0116 0.0259 0.0258
Trichomonas vaginalis conserved hypothetical protein 0.0222 0.0536 1
Brugia malayi Carboxylesterase family protein 0.0405 0.1012 0.8798
Trichomonas vaginalis protein phosphatase 2A, caeel, putative 0.021 0.0504 0.9403
Schistosoma mansoni neuropeptide receptor 0.0116 0.0259 0.0258
Loa Loa (eye worm) neuronal acetylcholine receptor protein 0.0028 0.003 0.0073
Entamoeba histolytica ubiquitin carboxyl-terminal hydrolase domain containing protein 0.0037 0.0052 0.2001
Schistosoma mansoni subfamily A1A unassigned peptidase (A01 family) 0.0191 0.0455 0.0453
Brugia malayi Eukaryotic aspartyl protease family protein 0.0191 0.0455 0.3946
Schistosoma mansoni subfamily A1A unassigned peptidase (A01 family) 0.0191 0.0455 0.0453
Entamoeba histolytica hypothetical protein 0.0033 0.0042 0.1548
Echinococcus multilocularis phd:f box containing protein 0.0032 0.004 0.01
Echinococcus multilocularis BC026374 protein (S09 family) 0.0068 0.0135 0.0347
Trichomonas vaginalis protein phosphatase 2A, regulatory subunit, putative 0.002 0.001 0.0146
Loa Loa (eye worm) serine/threonine protein phosphatase PP1-alpha catalytic subunit 0.0047 0.0079 0.02
Trichomonas vaginalis sugar transporter, putative 0.0031 0.0038 0.0681
Echinococcus multilocularis cadherin EGF LAG seven pass G type receptor 0.0048 0.0081 0.0205
Echinococcus granulosus calcium:calmodulin dependent protein kinase type 0.0068 0.0134 0.0344
Schistosoma mansoni subfamily A1A unassigned peptidase (A01 family) 0.0191 0.0455 0.0453
Mycobacterium leprae possible inositol monophosphatase SubH (IMPase) (inositol-1-phosphatase) (I-1-Pase ). 0.004 0.0061 0.3961
Brugia malayi Nuclear hormone receptor family member nhr-49 0.0021 0.001 0.0075
Loa Loa (eye worm) hypothetical protein 0.004 0.0062 0.0156
Loa Loa (eye worm) hypothetical protein 0.0027 0.0027 0.0064
Schistosoma mansoni intermediate filament proteins 0.0027 0.0027 0.0025
Trypanosoma cruzi FHA domain containing protein, putative 0.0019 0.0007 0.0037
Trypanosoma cruzi metacaspase, putative 0.0017 0.0002 0.0009
Brugia malayi Cation transporter family protein 0.0061 0.0115 0.0989
Plasmodium vivax aspartyl proteinase, putative 0.0191 0.0455 0.1878
Echinococcus granulosus nAChR subunit 0.0061 0.0115 0.0296
Onchocerca volvulus 0.0031 0.0038 0.0162
Brugia malayi jmjC domain containing protein 0.0032 0.004 0.0333
Loa Loa (eye worm) jmjC domain-containing protein 0.0032 0.004 0.01
Echinococcus multilocularis g protein linked acetylcholine receptor gar 2a 0.0116 0.0259 0.0671
Onchocerca volvulus 0.0031 0.0038 0.0162
Brugia malayi Inositol-1 0.0045 0.0073 0.0619
Brugia malayi Nuclear hormone receptor family member nhr-3 0.0021 0.001 0.0075
Echinococcus multilocularis Transcription factor, JmjC domain containing protein 0.012 0.0269 0.0696
Loa Loa (eye worm) nuclear hormone receptor family member nhr-14 0.0021 0.001 0.0022
Plasmodium vivax calcium-dependent protein kinase, putative 0.0068 0.0134 0.0549
Toxoplasma gondii poly(ADP-ribose) polymerase catalytic domain-containing protein 0.0019 0.0007 0.0034
Brugia malayi Neurotransmitter-gated ion-channel ligand binding domain containing protein 0.0061 0.0115 0.0989
Entamoeba histolytica acetyltransferase, GNAT family 0.0044 0.0072 0.2858
Echinococcus multilocularis thyroid hormone receptor alpha 0.0021 0.001 0.0022
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0021 0.001 0.0022
Loa Loa (eye worm) hypothetical protein 0.0019 0.0007 0.0014
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0116 0.0259 0.0258
Loa Loa (eye worm) hypothetical protein 0.0101 0.022 0.0568
Schistosoma mansoni protein phosphatase 2a regulatory subunit 0.002 0.001 0.0008
Schistosoma mansoni transcription factor LCR-F1 0.0106 0.0233 0.0231
Trichomonas vaginalis sugar transporter, putative 0.0031 0.0038 0.0681
Loa Loa (eye worm) aspartic protease BmAsp-1 0.0191 0.0455 0.118
Loa Loa (eye worm) intermediate filament protein 0.0027 0.0027 0.0064
Loa Loa (eye worm) hypothetical protein 0.0071 0.0142 0.0366
Echinococcus multilocularis rhodopsin orphan GPCR 0.0116 0.0259 0.0671
Trypanosoma cruzi JmjC domain, hydroxylase, putative 0.0032 0.004 0.0205
Echinococcus multilocularis g protein linked acetylcholine receptor gar 2a 0.0116 0.0259 0.0671
Loa Loa (eye worm) hypothetical protein 0.0116 0.0259 0.0671
Onchocerca volvulus Dopamine\/Ecdysteroid receptor homolog 0.0116 0.0259 0.1312
Trypanosoma cruzi hexose transporter, putative 0.0038 0.0055 0.0282
Toxoplasma gondii prolyl-tRNA synthetase (ProRS) 0.0078 0.0159 0.099
Trypanosoma cruzi hypothetical protein, conserved 0.0019 0.0007 0.0037
Echinococcus multilocularis transfer RNA-Lys 0.0035 0.0048 0.0121
Loa Loa (eye worm) hypothetical protein 0.0028 0.003 0.0073
Loa Loa (eye worm) hypothetical protein 0.016 0.0372 0.0965
Onchocerca volvulus 0.0068 0.0135 0.0665
Trichomonas vaginalis bsu-protein phosphatase, putative 0.0051 0.009 0.1656
Echinococcus multilocularis nicotinic acetylcholine receptor alpha subunit 0.0061 0.0115 0.0296
Trichomonas vaginalis sugar transporter, putative 0.0031 0.0038 0.0681
Trichomonas vaginalis protein phosphatase-7, caeel, putative 0.021 0.0504 0.9403
Echinococcus multilocularis biogenic amine (5HT) receptor 0.0116 0.0259 0.0671
Trichomonas vaginalis protein phosphatase, caeel, putative 0.021 0.0504 0.9403
Leishmania major glucose transporter, lmgt1 0.0069 0.0136 0.07
Echinococcus granulosus calcium:calmodulin dependent protein kinase type 0.0068 0.0134 0.0344
Echinococcus granulosus sterol regulatory element binding protein 0.0044 0.0072 0.0182
Echinococcus granulosus neuropeptide FF receptor 2 0.0116 0.0259 0.0671
Loa Loa (eye worm) serine/threonine protein phosphatase 2A 0.0074 0.0149 0.0382
Brugia malayi nicotinic acetylcholine receptor beta-1 chain precursor 0.0061 0.0115 0.0989
Echinococcus granulosus Transcription factor JmjC domain containing protein 0.012 0.0269 0.0696
Loa Loa (eye worm) hypothetical protein 0.0028 0.003 0.0073
Echinococcus granulosus jumonji domain containing 1A 0.0032 0.004 0.01
Schistosoma mansoni protein phosphatase-1 0.0047 0.0079 0.0077
Echinococcus granulosus neuropeptide Y receptor 0.0116 0.0259 0.0671
Echinococcus multilocularis G-protein coupled receptor, putative 0.0116 0.0259 0.0671
Loa Loa (eye worm) hypothetical protein 0.0061 0.0115 0.0296
Brugia malayi Hypothetical 52.5 kDa protein ZK945.1 in chromosome II, putative 0.0071 0.0142 0.1223
Trypanosoma cruzi lysyl-tRNA synthetase, putative 0.005 0.0086 0.0441
Echinococcus multilocularis nicotinic acetylcholine receptor subunit alpha 8 0.0061 0.0115 0.0296
Echinococcus granulosus snurportin 1 0.0259 0.0631 0.1638
Echinococcus multilocularis muscleblind protein 1 0.0156 0.0363 0.0941
Trichomonas vaginalis sugar transport protein, putative 0.0031 0.0038 0.0681
Echinococcus granulosus solute carrier family 22 0.0031 0.0038 0.0095
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0021 0.001 0.0075
Echinococcus granulosus Protein patched homolog 1 0.0044 0.0072 0.0182
Schistosoma mansoni ubiquitously transcribed sex (X/Y) chromosome tetratricopeptide repeat protein-related 0.0032 0.004 0.0038
Echinococcus multilocularis acetylcholine receptor subunit beta 1 0.0061 0.0115 0.0296
Schistosoma mansoni protein phosphatase type 1 0.0047 0.0079 0.0077
Schistosoma mansoni rab6-interacting 0.0019 0.0007 0.0005
Onchocerca volvulus Rap guanine nucleotide exchange factor 1 homolog 0.0178 0.042 0.2145
Onchocerca volvulus 0.0116 0.0259 0.1312
Schistosoma mansoni cathepsin D (A01 family) 0.0191 0.0455 0.0453
Loa Loa (eye worm) hypothetical protein 0.0116 0.0259 0.0671
Brugia malayi putative serine/threonine phosphatase 0.0047 0.0079 0.067
Schistosoma mansoni biogenic amine (octopamine/dopamine) receptor 0.0116 0.0259 0.0258
Brugia malayi Neurotransmitter-gated ion-channel ligand binding domain containing protein 0.0061 0.0115 0.0989
Loa Loa (eye worm) hypothetical protein 0.0054 0.0098 0.025
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0135 0.0308 0.0306
Echinococcus granulosus ecdysone induced protein 78C 0.0021 0.001 0.0022
Echinococcus granulosus Niemann Pick C1 protein 0.0147 0.034 0.088
Loa Loa (eye worm) hypothetical protein 0.0024 0.002 0.0047
Schistosoma mansoni opsin-like receptor 0.0116 0.0259 0.0258
Brugia malayi Cell death protein 3 precursor 0.0058 0.0107 0.0914
Echinococcus granulosus glycine receptor subunit beta 0.0061 0.0115 0.0296
Trichomonas vaginalis sugar transporter, putative 0.0031 0.0038 0.0681
Schistosoma mansoni peptide (FMRFamide/somatostatin)-like receptor 0.0116 0.0259 0.0258
Loa Loa (eye worm) hypothetical protein 0.0044 0.0072 0.0182
Loa Loa (eye worm) hypothetical protein 0.0116 0.0259 0.0671
Trichomonas vaginalis protein phosphatase-1, putative 0.021 0.0504 0.9403
Schistosoma mansoni ubiquitin-specific peptidase 2 (C19 family) 0.0037 0.0052 0.0051
Schistosoma mansoni hypothetical protein 0.004 0.0062 0.006
Trichomonas vaginalis protein phsophatase-2A, putative 0.021 0.0504 0.9403
Brugia malayi Nuclear hormone receptor family member nhr-1 0.0021 0.001 0.0075
Echinococcus multilocularis beta LACTamase domain containing family member 0.0071 0.0142 0.0366
Mycobacterium tuberculosis Probable conserved lipoprotein 0.0071 0.0142 0.0943
Echinococcus multilocularis G protein coupled 5 hydroxytryptamine receptor 0.0116 0.0259 0.0671
Echinococcus granulosus nAChR subunit 0.0033 0.0042 0.0105
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0116 0.0259 0.0258
Brugia malayi Cation transporter family protein 0.0061 0.0115 0.0989
Trichomonas vaginalis D-aminoacylase, putative 0.0071 0.0142 0.263
Trichomonas vaginalis chromosome transmission fidelity factor, putative 0.0019 0.0007 0.0103
Chlamydia trachomatis proline--tRNA ligase 0.0024 0.0018 0.1375
Schistosoma mansoni neuroligin 3 (S09 family) 0.0068 0.0135 0.0133
Loa Loa (eye worm) hypothetical protein 0.0031 0.0038 0.0095
Brugia malayi Neurotransmitter-gated ion-channel ligand binding domain containing protein 0.0028 0.003 0.0245
Echinococcus multilocularis neuropeptide s receptor 0.0116 0.0259 0.0671
Schistosoma mansoni loxhd1 0.0019 0.0007 0.0005
Loa Loa (eye worm) sugar transporter 0.0031 0.0038 0.0095
Giardia lamblia Ser/Thr protein phosphatase PP1-alpha 2 catalytic subunit 0.0051 0.009 0.5868
Trichomonas vaginalis conserved hypothetical protein 0.0031 0.0038 0.0681
Schistosoma mansoni lysyl-tRNA synthetase 0.005 0.0086 0.0084
Loa Loa (eye worm) hypothetical protein 0.015 0.0348 0.0902
Loa Loa (eye worm) acetylcholinesterase 1 0.0405 0.1012 0.263
Loa Loa (eye worm) hypothetical protein 0.0061 0.0115 0.0296
Echinococcus granulosus solute carrier family 2 facilitated glucose 0.0222 0.0536 0.1391
Echinococcus granulosus apoptotic protease activating factor 1 0.004 0.0062 0.0156
Echinococcus multilocularis glycine receptor subunit beta 0.0061 0.0115 0.0296
Loa Loa (eye worm) hypothetical protein 0.0405 0.1012 0.263
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0021 0.001 0.0075
Brugia malayi gonadotropin-releasing hormone receptor 2 0.0116 0.0259 0.2245
Echinococcus multilocularis caspase 2 0.0058 0.0107 0.0273
Schistosoma mansoni hypothetical protein 0.0043 0.0068 0.0066
Echinococcus multilocularis g protein coupled receptor 0.0116 0.0259 0.0671
Schistosoma mansoni neuropeptide F-like receptor 0.0116 0.0259 0.0258
Brugia malayi steroid hormone receptor 0.0021 0.001 0.0075
Trichomonas vaginalis conserved hypothetical protein 0.0031 0.0038 0.0681
Plasmodium falciparum plasmepsin II 0.0191 0.0455 0.1878
Plasmodium falciparum protein kinase 6 0.0944 0.2413 1
Plasmodium falciparum proline--tRNA ligase 0.0078 0.0159 0.0653
Trichomonas vaginalis sugar transporter, putative 0.0069 0.0136 0.2519
Brugia malayi Importin beta-1 subunit 0.0024 0.002 0.0158
Trichomonas vaginalis bsu-protein phosphatase, putative 0.0047 0.0079 0.1441
Brugia malayi Intermediate filament tail domain containing protein 0.0027 0.0027 0.0215
Loa Loa (eye worm) neuropeptide F receptor 0.0116 0.0259 0.0671
Schistosoma mansoni alpha-1 adrenergic receptor 0.0116 0.0259 0.0258
Loa Loa (eye worm) hypothetical protein 0.0033 0.0042 0.0105
Schistosoma mansoni subfamily A1A unassigned peptidase (A01 family) 0.0191 0.0455 0.0453
Trichomonas vaginalis protein phsophatase-2A, putative 0.021 0.0504 0.9403
Brugia malayi Neurotransmitter-gated ion-channel transmembrane region family protein 0.0033 0.0042 0.0352
Schistosoma mansoni Tr4/Tr2 (homologue) 0.0021 0.001 0.0009
Trichomonas vaginalis protein phosphatase, caeel, putative 0.021 0.0504 0.9403
Onchocerca volvulus 0.0048 0.0083 0.0394
Loa Loa (eye worm) protein phosphatase 2A regulatory subunit B' delta isoform 0.002 0.001 0.002
Echinococcus granulosus protein phosphatase 1, catalytic subunit, beta isozyme 0.0051 0.009 0.023
Mycobacterium ulcerans exodeoxyribonuclease III protein XthA 0.0038 0.0057 0.3653
Trichomonas vaginalis serine/threonine protein phosphatase, putative 0.0051 0.009 0.1656
Mycobacterium tuberculosis Inositol-1-monophosphatase SuhB 0.004 0.0061 0.0205
Loa Loa (eye worm) hypothetical protein 0.0116 0.0259 0.0671
Loa Loa (eye worm) hypothetical protein 0.0028 0.003 0.0073
Trichomonas vaginalis protein phosphatase-1, putative 0.0047 0.0079 0.1441
Brugia malayi hypothetical protein 0.004 0.0062 0.0521
Schistosoma mansoni single-minded 0.0048 0.0081 0.0079
Loa Loa (eye worm) serine/threonine protein phosphatase PP1 isozyme 1 0.0047 0.0079 0.02
Echinococcus multilocularis Basic leucine zipper (bZIP) transcription 0.0106 0.0233 0.0602
Loa Loa (eye worm) hypothetical protein 0.0033 0.0042 0.0105
Treponema pallidum exodeoxyribonuclease (exoA) 0.0038 0.0057 1
Trypanosoma cruzi hypothetical protein, conserved 0.0074 0.0149 0.0763
Echinococcus granulosus rhodopsin orphan GPCR 0.0116 0.0259 0.0671
Loa Loa (eye worm) hypothetical protein 0.0116 0.0259 0.0671
Loa Loa (eye worm) hypothetical protein 0.0191 0.0455 0.118
Brugia malayi hypothetical protein 0.0458 0.1149 1
Trypanosoma brucei protein phosphatase 1, putative 0.0051 0.009 0.0454
Trichomonas vaginalis sugar transporter, putative 0.0031 0.0038 0.0681
Schistosoma mansoni serine/threonine protein kinase 0.0068 0.0134 0.0132
Brugia malayi Muscleblind-like protein 0.0156 0.0363 0.3149
Schistosoma mansoni lysyl-tRNA synthetase 0.005 0.0086 0.0084
Leishmania major prolyl-tRNA synthetase, putative,bifunctional aminoacyl-tRNA synthetase, putative 0.0078 0.0159 0.0817
Trichomonas vaginalis sugar transporter, putative 0.0069 0.0136 0.2519
Plasmodium falciparum plasmepsin VII 0.0191 0.0455 0.1878
Trichomonas vaginalis ap endonuclease, putative 0.0038 0.0057 0.1026
Trypanosoma brucei sugar transporter, putative 0.0031 0.0038 0.0187
Loa Loa (eye worm) hypothetical protein 0.0021 0.001 0.0022
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0116 0.0259 0.0258
Trichomonas vaginalis conserved hypothetical protein 0.0019 0.0007 0.0103
Onchocerca volvulus 0.0027 0.0027 0.0102
Loa Loa (eye worm) hypothetical protein 0.0061 0.0115 0.0296
Brugia malayi photoreceptor-specific nuclear receptor 0.0021 0.001 0.0075
Echinococcus granulosus glycine receptor subunit beta 0.0061 0.0115 0.0296
Loa Loa (eye worm) hypothetical protein 0.002 0.001 0.002
Loa Loa (eye worm) nicotinic acetylcholine receptor alpha subunit 0.0061 0.0115 0.0296
Echinococcus granulosus muscleblind protein 0.0156 0.0363 0.0941
Echinococcus granulosus Nuclear hormone receptor family member nhr 41 0.0021 0.001 0.0022
Echinococcus granulosus rhodopsin orphan GPCR 0.0116 0.0259 0.0671
Schistosoma mansoni caspase-7 (C14 family) 0.0058 0.0107 0.0105
Schistosoma mansoni protein phosphatase pp2a regulatory subunit B 0.0074 0.0149 0.0147
Echinococcus multilocularis Peptidase C19, ubiquitin carboxyl terminal hydrolase 2 0.0037 0.0052 0.0132
Schistosoma mansoni ancient conserved domain protein 2 (cyclin m2) 0.0116 0.0259 0.0258
Leishmania major aldehyde dehydrogenase, mitochondrial precursor 0.0069 0.0135 0.0695
Loa Loa (eye worm) hypothetical protein 0.0405 0.1012 0.263
Loa Loa (eye worm) hypothetical protein 0.1492 0.384 1
Trichomonas vaginalis Importin beta-1 subunit, putative 0.002 0.0008 0.0115
Loa Loa (eye worm) hypothetical protein 0.0061 0.0115 0.0296
Trypanosoma cruzi JmjC domain, hydroxylase, putative 0.0032 0.004 0.0205
Schistosoma mansoni RAR-like nuclear receptor 0.0021 0.001 0.0009
Onchocerca volvulus 0.0116 0.0259 0.1312
Brugia malayi glutamate-gated chloride channel alpha3A subunit, putative 0.0028 0.003 0.0245
Trichomonas vaginalis penicillin-binding protein, putative 0.0071 0.0142 0.263
Echinococcus multilocularis lamin dm0 0.0027 0.0027 0.0064
Loa Loa (eye worm) CAMK/CAMK2 protein kinase 0.0068 0.0134 0.0344
Brugia malayi hypothetical protein 0.0116 0.0259 0.2245
Brugia malayi neuropeptide F receptor 0.0116 0.0259 0.2245
Mycobacterium tuberculosis Probable exodeoxyribonuclease III protein XthA (exonuclease III) (EXO III) (AP endonuclease VI) 0.0038 0.0057 0.0167
Mycobacterium tuberculosis Probable lipase LipD 0.0071 0.0142 0.0943
Leishmania major prolyl-tRNA synthetase, putative,bifunctional aminoacyl-tRNA synthetase, putative 0.0078 0.0159 0.0817
Schistosoma mansoni acetylcholinesterase 0.0068 0.0135 0.0133
Trypanosoma brucei hypothetical protein, conserved 0.0071 0.0142 0.0721
Echinococcus granulosus aldehyde dehydrogenase mitochondrial 0.0069 0.0135 0.0348
Loa Loa (eye worm) follicle stimulating hormone receptor 0.031 0.0763 0.1983
Echinococcus granulosus rhodopsin orphan GPCR 0.0116 0.0259 0.0671
Trypanosoma cruzi glucose transporter, putative 0.0031 0.0038 0.0196
Loa Loa (eye worm) hypothetical protein 0.0031 0.0038 0.0095
Trypanosoma brucei glucose transporter, putative 0.0069 0.0136 0.0691
Brugia malayi putative neuropeptide receptor NPR1 0.0116 0.0259 0.2245
Echinococcus multilocularis arachidonate 5 lipoxygenase 0.0054 0.0097 0.0249
Echinococcus multilocularis Niemann Pick C1 protein 0.0147 0.034 0.088
Loa Loa (eye worm) hypothetical protein 0.0028 0.003 0.0073
Schistosoma mansoni protein phosphatase type 1 0.0051 0.009 0.0088
Echinococcus granulosus serine:threonine protein phosphatase 2A 56 kDa 0.002 0.001 0.002
Brugia malayi CHE-14 protein 0.0044 0.0072 0.0609
Onchocerca volvulus 0.0031 0.0038 0.0162
Schistosoma mansoni nAChR subunit 0.0061 0.0115 0.0114
Toxoplasma gondii ABC1 family protein 0.0071 0.0142 0.0883
Toxoplasma gondii histone lysine demethylase JMJC1/KDM5D/JARID1D 0.0032 0.004 0.024
Onchocerca volvulus Putative nachr subunit 0.0061 0.0115 0.0563
Onchocerca volvulus 0.004 0.0062 0.0284
Echinococcus granulosus GPCR family 2 0.0048 0.0081 0.0205
Trypanosoma cruzi hexose transporter, putative 0.0031 0.0038 0.0196
Loa Loa (eye worm) exodeoxyribonuclease III family protein 0.0038 0.0057 0.0143
Trichomonas vaginalis serine/threonine protein phosphatase, putative 0.021 0.0504 0.9403
Loa Loa (eye worm) hypothetical protein 0.0116 0.0259 0.0671
Brugia malayi Nuclear hormone receptor family member nhr-41 0.0021 0.001 0.0075
Onchocerca volvulus 0.0068 0.0135 0.0665
Echinococcus granulosus ubiquitin specific protease 41 0.0037 0.0052 0.0132
Brugia malayi hypothetical protein 0.0028 0.003 0.0245
Mycobacterium ulcerans fusion protein of transposase for IS2606 and sialic acid-transport integral membrane protein NanT 0.0031 0.0038 0.2288
Loa Loa (eye worm) hypothetical protein 0.0028 0.003 0.0073
Brugia malayi RE15519p 0.0116 0.0259 0.2245
Trichomonas vaginalis sugar transporter, putative 0.0031 0.0038 0.0681
Loa Loa (eye worm) unidentified vitellogenin-linked transcript protein 6 0.0116 0.0259 0.0671
Mycobacterium ulcerans lipase LipD 0.0071 0.0142 1
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0021 0.001 0.0075
Onchocerca volvulus Huntingtin homolog 0.0148 0.0342 0.1741
Schistosoma mansoni photoreceptor-specific nuclear receptor related 0.0021 0.001 0.0009
Schistosoma mansoni nAChR subunit 0.0061 0.0115 0.0114
Schistosoma mansoni nAChR subunit 0.0028 0.003 0.0028
Schistosoma mansoni nAChR subunit 0.0061 0.0115 0.0114
Brugia malayi hypoxia-induced factor 1 0.0147 0.034 0.2947
Echinococcus multilocularis gamma aminobutyric acid receptor subunit 0.0028 0.003 0.0073
Trypanosoma cruzi apurinic/apyrimidinic endonuclease 0.0038 0.0057 0.029
Echinococcus multilocularis serotonin receptor 0.1492 0.384 1
Entamoeba histolytica hypothetical protein 0.002 0.0008 0.003
Loa Loa (eye worm) hypothetical protein 0.0116 0.0259 0.0671
Brugia malayi Major Facilitator Superfamily protein 0.0031 0.0038 0.0317
Trichomonas vaginalis importin beta-1, putative 0.002 0.0008 0.0115
Echinococcus granulosus glycine receptor subunit alpha 1 0.0061 0.0115 0.0296
Trichomonas vaginalis sugar transporter, putative 0.0031 0.0038 0.0681
Trichomonas vaginalis conserved hypothetical protein 0.0031 0.0038 0.0681
Brugia malayi hypothetical protein 0.0191 0.0455 0.3946
Trichomonas vaginalis RNA polymerase II ctd phosphatase, putative 0.0019 0.0007 0.0103
Loa Loa (eye worm) hypothetical protein 0.0204 0.0487 0.1264
Trichomonas vaginalis glucose transporter, putative 0.0069 0.0136 0.2519
Onchocerca volvulus 0.0028 0.003 0.0119
Trichomonas vaginalis protein phosphatase-1, putative 0.021 0.0504 0.9403
Onchocerca volvulus Bile acid receptor homolog 0.0021 0.001 0.0018
Brugia malayi Nuclear hormone receptor-like 1 0.0021 0.001 0.0075
Loa Loa (eye worm) nuclear hormone receptor family member nhr-49 0.0021 0.001 0.0022
Echinococcus multilocularis neuropeptide receptor A26 0.0116 0.0259 0.0671
Trichomonas vaginalis conserved hypothetical protein 0.0031 0.0038 0.0681
Brugia malayi Doublecortin family protein 0.0019 0.0007 0.0045
Schistosoma mansoni chromosome transmission fidelity factor 0.0019 0.0007 0.0005
Echinococcus multilocularis fmrfamide receptor 0.0116 0.0259 0.0671
Trichomonas vaginalis protein phosphatase, caeel, putative 0.021 0.0504 0.9403
Loa Loa (eye worm) hypothetical protein 0.0116 0.0259 0.0671
Echinococcus granulosus histone acetyltransferase KAT2B 0.0048 0.0082 0.0209
Schistosoma mansoni gcn5proteinral control of amino-acid synthesis 5-like 2 gcnl2 0.0164 0.0383 0.0381
Trypanosoma cruzi myo-inositol-1(or 4)-monophosphatase 1, putative 0.0045 0.0073 0.0374
Echinococcus multilocularis nAChR subunit 0.0061 0.0115 0.0296
Entamoeba histolytica hypothetical protein 0.005 0.0086 0.349
Mycobacterium tuberculosis POSSIBLE PARA-NITROBENZYL ESTERASE (FRAGMENT) 0.0068 0.0135 0.0878
Schistosoma mansoni nicotinic acetylcholine receptor alpha 0.0033 0.0042 0.004
Loa Loa (eye worm) excitatory GABA receptor EXP-1A 0.0061 0.0115 0.0296
Loa Loa (eye worm) hypothetical protein 0.0458 0.1149 0.299
Loa Loa (eye worm) hypothetical protein 0.0047 0.0079 0.02
Trypanosoma cruzi serine/threonine-protein phosphatase PP1, putative 0.0167 0.0392 0.2011
Echinococcus multilocularis acetylcholinesterase 0.0405 0.1012 0.263
Echinococcus granulosus nicotinic acetylcholine receptor subunit alpha 8 0.0061 0.0115 0.0296
Brugia malayi G-protein coupled receptor 0.0116 0.0259 0.2245
Loa Loa (eye worm) hypothetical protein 0.0156 0.0363 0.0941
Brugia malayi beta-lactamase family protein 0.0071 0.0142 0.1223
Trichomonas vaginalis cat eye syndrome critical region protein 2, cscr2, putative 0.0048 0.0082 0.1505
Plasmodium falciparum plasmepsin III 0.0191 0.0455 0.1878
Schistosoma mansoni hypothetical protein 0.0045 0.0075 0.0073
Schistosoma mansoni adenoreceptor 0.0116 0.0259 0.0258
Echinococcus multilocularis solute carrier family 2 facilitated glucose 0.0222 0.0536 0.1391
Echinococcus granulosus solute carrier family 22 0.0031 0.0038 0.0095
Trichomonas vaginalis Importin beta-1 subunit, putative 0.002 0.0008 0.0115
Loa Loa (eye worm) steroid hormone receptor 0.0021 0.001 0.0022
Schistosoma mansoni glucose transport protein 0.0222 0.0536 0.0534
Loa Loa (eye worm) hypothetical protein 0.0031 0.0038 0.0095
Brugia malayi hypothetical protein 0.0031 0.0038 0.0317
Echinococcus granulosus tm gpcr rhodopsin 0.0116 0.0259 0.0671
Echinococcus granulosus gamma aminobutyric acid receptor subunit 0.0028 0.003 0.0073
Echinococcus granulosus serine:threonine protein phosphatase PP1 beta 0.0051 0.009 0.023
Trichomonas vaginalis phosphoserine/threonine phosphatase, putative 0.021 0.0504 0.9403
Schistosoma mansoni protein kinase 0.0068 0.0134 0.0132
Loa Loa (eye worm) hypothetical protein 0.0019 0.0007 0.0014
Plasmodium vivax replication factor C subunit 1, putative 0.0019 0.0007 0.0023
Trichomonas vaginalis sugar transporter, putative 0.0031 0.0038 0.0681
Echinococcus granulosus Jumonji AT rich interactive domain 1B 0.0032 0.004 0.01
Loa Loa (eye worm) hypothetical protein 0.0048 0.0081 0.0205
Loa Loa (eye worm) hypothetical protein 0.0116 0.0259 0.0671
Loa Loa (eye worm) hypothetical protein 0.0116 0.0259 0.0671
Trichomonas vaginalis protein phosphatase-1, putative 0.021 0.0504 0.9403
Mycobacterium tuberculosis Probable hydrolase 0.0071 0.0142 0.0943
Loa Loa (eye worm) hypothetical protein 0.0031 0.0038 0.0095
Loa Loa (eye worm) hypothetical protein 0.0061 0.0115 0.0296
Echinococcus granulosus solute carrier family 22 0.0031 0.0038 0.0095
Trypanosoma brucei JmjC domain, hydroxylase, putative 0.0032 0.004 0.0196
Loa Loa (eye worm) hypothetical protein 0.0116 0.0259 0.0671
Trichomonas vaginalis sugar transporter, putative 0.0031 0.0038 0.0681
Echinococcus multilocularis serine:threonine protein phosphatase PP1 gamma 0.0051 0.009 0.023
Schistosoma mansoni hypothetical protein 0.0043 0.0068 0.0066
Trypanosoma brucei hypothetical protein, conserved 0.0074 0.0149 0.0754
Onchocerca volvulus 0.0033 0.0042 0.0183
Echinococcus granulosus single minded 2 0.0035 0.0048 0.0121
Echinococcus multilocularis serine:threonine protein phosphatase PP1 beta 0.0051 0.009 0.023
Leishmania major serine/threonine-protein phosphatase PP1, putative 0.0251 0.0609 0.3126
Brugia malayi Serine/threonine protein phosphatase PP1-alpha catalytic subunit 0.0047 0.0079 0.067
Echinococcus granulosus calcium dependent protein kinase 0.0064 0.0123 0.0316
Brugia malayi Corticotropin releasing factor receptor 2 precursor, putative 0.015 0.0348 0.3018
Loa Loa (eye worm) hypothetical protein 0.0116 0.0259 0.0671
Brugia malayi hypothetical protein 0.0106 0.0233 0.2012
Trichomonas vaginalis protein phsophatase-2A, putative 0.021 0.0504 0.9403
Schistosoma mansoni opsin-like receptor 0.0116 0.0259 0.0258
Onchocerca volvulus 0.0116 0.0259 0.1312
Echinococcus multilocularis cathepsin d (lysosomal aspartyl protease) 0.0191 0.0455 0.118
Echinococcus multilocularis solute carrier family 2 facilitated glucose 0.0222 0.0536 0.1391
Echinococcus multilocularis Sugar transporter ERD6 protein 0.0031 0.0038 0.0095
Onchocerca volvulus 0.0031 0.0038 0.0162
Schistosoma mansoni protein kinase 0.0068 0.0134 0.0132
Schistosoma mansoni nAChR subunit 0.0028 0.003 0.0028
Onchocerca volvulus 0.0116 0.0259 0.1312
Plasmodium falciparum protein kinase 7 0.0628 0.1592 0.6594
Trypanosoma cruzi metacaspase, putative 0.0017 0.0002 0.0009
Loa Loa (eye worm) hypothetical protein 0.0019 0.0007 0.0014
Echinococcus multilocularis solute carrier family 22 0.0031 0.0038 0.0095
Brugia malayi Neurotransmitter-gated ion-channel ligand binding domain containing protein 0.0061 0.0115 0.0989
Trichomonas vaginalis sugar transporter, putative 0.0031 0.0038 0.0681
Schistosoma mansoni nAChR subunit 0.0061 0.0115 0.0114
Loa Loa (eye worm) hypothetical protein 0.0068 0.0135 0.0347
Brugia malayi exodeoxyribonuclease III family protein 0.0038 0.0057 0.0477
Schistosoma mansoni nAChR subunit 0.0061 0.0115 0.0114
Trypanosoma brucei glucose transporter, putative 0.0069 0.0136 0.0691
Trichomonas vaginalis sugar transporter, putative 0.0031 0.0038 0.0681
Brugia malayi Neurotransmitter-gated ion-channel transmembrane region family protein 0.0061 0.0115 0.0989
Echinococcus granulosus ubiquitin carboxyl terminal hydrolase 8 0.0037 0.0052 0.0132
Brugia malayi Bifunctional aminoacyl-tRNA synthetase 0.0067 0.013 0.1121
Trypanosoma brucei glucose transporter 2A 0.0069 0.0136 0.0691
Echinococcus multilocularis fmrfamide receptor 0.0116 0.0259 0.0671
Schistosoma mansoni protein phosphatase type 1 0.0051 0.009 0.0088
Plasmodium vivax importin-beta 2, putative 0.0024 0.002 0.0075
Trypanosoma cruzi protein phosphatase 2A regulatory subunit, putative 0.0074 0.0149 0.0763
Loa Loa (eye worm) hypothetical protein 0.0061 0.0115 0.0296
Brugia malayi hypothetical protein 0.0028 0.003 0.0245
Echinococcus multilocularis solute carrier family 2 facilitated glucose 0.0222 0.0536 0.1391
Trichomonas vaginalis bromodomain-containing protein, putative 0.0048 0.0082 0.1505
Brugia malayi G protein-coupled receptor F59B2.13 0.0116 0.0259 0.2245
Loa Loa (eye worm) sugar transporter 0.0222 0.0536 0.1391
Trypanosoma cruzi metacaspase, putative 0.0017 0.0002 0.0009
Schistosoma mansoni lipoxygenase 0.0054 0.0097 0.0095
Trypanosoma brucei serine threonine-protein phosphatase PP1, putative 0.0047 0.0079 0.0395
Loa Loa (eye worm) hypothetical protein 0.0116 0.0259 0.0671
Echinococcus multilocularis inositol monophosphatase 1 0.0045 0.0073 0.0185
Plasmodium vivax ataxin-2 like protein, putative 0.0101 0.022 0.0904
Trichomonas vaginalis ap endonuclease, putative 0.0038 0.0057 0.1026
Echinococcus granulosus biogenic amine 5HT receptor 0.1492 0.384 1
Schistosoma mansoni hypothetical protein 0.0116 0.0259 0.0258
Trichomonas vaginalis serine/threonine protein phosphatase, putative 0.0047 0.0079 0.1441
Schistosoma mansoni nAChR subunit 0.0061 0.0115 0.0114
Echinococcus multilocularis neuropeptide receptor 0.0116 0.0259 0.0671
Trichomonas vaginalis bsu-protein phosphatase, putative 0.021 0.0504 0.9403
Loa Loa (eye worm) hypothetical protein 0.0116 0.0259 0.0671
Mycobacterium tuberculosis Probable esterase LipL 0.0071 0.0142 0.0943
Loa Loa (eye worm) hypothetical protein 0.0116 0.0259 0.0671
Brugia malayi G-protein coupled receptor 0.0116 0.0259 0.2245
Brugia malayi hypothetical protein 0.0116 0.0259 0.2245
Onchocerca volvulus 0.0031 0.0038 0.0162
Brugia malayi Calcitonin receptor-like protein seb-1 0.015 0.0348 0.3018
Echinococcus granulosus lysyl tRNA synthetase 0.005 0.0086 0.0219
Plasmodium vivax plasmepsin V, putative 0.0191 0.0455 0.1878
Toxoplasma gondii sugar transporter ST3 0.0031 0.0038 0.0229
Loa Loa (eye worm) hypothetical protein 0.0067 0.013 0.0335
Trichomonas vaginalis protein phsophatase-2A, putative 0.021 0.0504 0.9403
Brugia malayi hypothetical protein 0.0019 0.0007 0.0045
Trichomonas vaginalis D-aminoacylase, putative 0.0071 0.0142 0.263
Loa Loa (eye worm) nuclear hormone receptor family member nhr-40 0.0021 0.001 0.0022
Trichomonas vaginalis protein phosphatase, caeel, putative 0.021 0.0504 0.9403
Echinococcus granulosus rhodopsin orphan GPCR 0.0116 0.0259 0.0671
Schistosoma mansoni sugar transporter 0.0031 0.0038 0.0036
Echinococcus multilocularis neuropeptides capa receptor 0.0116 0.0259 0.0671
Loa Loa (eye worm) ligand-Gated ion Channel family member 0.0061 0.0115 0.0296
Loa Loa (eye worm) hypothetical protein 0.0116 0.0259 0.0671
Brugia malayi Protein-tyrosine phosphatase containing protein 0.0423 0.1059 0.9209
Mycobacterium ulcerans integral membrane transport protein 0.0031 0.0038 0.2288
Loa Loa (eye worm) hypothetical protein 0.0028 0.003 0.0073
Schistosoma mansoni nAChR subunit (ShAR1-beta2-like) 0.0061 0.0115 0.0114
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0135 0.0308 0.0306
Schistosoma mansoni aldehyde dehydrogenase 0.0069 0.0135 0.0134
Loa Loa (eye worm) nicotinic acetylcholine receptor non-alpha subunit 0.0061 0.0115 0.0296
Brugia malayi jmjC domain containing protein 0.012 0.0269 0.2327
Loa Loa (eye worm) hypothetical protein 0.0019 0.0007 0.0014
Loa Loa (eye worm) hypothetical protein 0.0031 0.0038 0.0095
Brugia malayi hypothetical protein 0.0116 0.0259 0.2245
Schistosoma mansoni subfamily A1A unassigned peptidase (A01 family) 0.0191 0.0455 0.0453
Brugia malayi hypothetical protein 0.0065 0.0127 0.1088
Trichomonas vaginalis protein phsophatase-2A, putative 0.021 0.0504 0.9403
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0116 0.0259 0.0258
Loa Loa (eye worm) hypothetical protein 0.0116 0.0259 0.0671
Brugia malayi Neurotransmitter-gated ion-channel transmembrane region family protein 0.0033 0.0042 0.0352
Loa Loa (eye worm) hypothetical protein 0.0116 0.0259 0.0671
Plasmodium falciparum ataxin-2 like protein, putative 0.0101 0.022 0.0904
Echinococcus multilocularis peptide (allatostatin:somatostatin) 0.0116 0.0259 0.0671
Echinococcus granulosus biogenic amine 5HT receptor 0.0116 0.0259 0.0671
Brugia malayi Major Facilitator Superfamily protein 0.0031 0.0038 0.0317
Toxoplasma gondii histone lysine acetyltransferase GCN5-A 0.0048 0.0082 0.0505
Echinococcus multilocularis orexin receptor type 2 0.0116 0.0259 0.0671
Loa Loa (eye worm) hypothetical protein 0.0031 0.0038 0.0095
Trypanosoma brucei protein phosphatase 1 0.0167 0.0392 0.2004
Trichomonas vaginalis protein phosphatase, caeel, putative 0.021 0.0504 0.9403
Echinococcus granulosus Peptidase C19 ubiquitin carboxyl terminal hydrolase 2 0.0037 0.0052 0.0132
Loa Loa (eye worm) hypothetical protein 0.0021 0.001 0.0022
Mycobacterium ulcerans aldehyde dehydrogenase 0.0069 0.0135 0.9496
Echinococcus granulosus Polycystic kidney disease protein 0.0019 0.0007 0.0013
Echinococcus granulosus FTZ F1 nuclear receptor protein 0.0021 0.001 0.0022
Loa Loa (eye worm) hypothetical protein 0.0061 0.0115 0.0296
Echinococcus granulosus synaptic vesicle 2 protein 0.0031 0.0038 0.0095
Echinococcus granulosus growth hormone secretagogue receptor type 1 0.0116 0.0259 0.0671
Schistosoma mansoni nuclear hormone receptor 0.0021 0.001 0.0009
Trypanosoma cruzi serine/threonine-protein phosphatase PP1, putative 0.0251 0.0609 0.3126
Echinococcus multilocularis carboxylesterase 5A 0.0405 0.1012 0.263
Echinococcus granulosus 7TM GPCR rhodopsin 0.0116 0.0259 0.0671
Mycobacterium ulcerans aldehyde dehydrogenase 0.0069 0.0135 0.9496
Onchocerca volvulus 0.0031 0.0038 0.0162
Echinococcus granulosus microtubule associated protein 2 0.0728 0.1851 0.4817
Echinococcus multilocularis glycine receptor subunit alpha 1 0.0061 0.0115 0.0296
Giardia lamblia Prolyl-tRNA synthetase 0.0067 0.013 0.8716
Brugia malayi Serine/threonine protein phosphatase PP1-beta catalytic subunit 0.0051 0.009 0.077
Onchocerca volvulus Protein phosphatase PP2A 55 kDa regulatory subunit homolog 0.0074 0.0149 0.0736
Loa Loa (eye worm) hypothetical protein 0.0116 0.0259 0.0671
Onchocerca volvulus 0.0061 0.0115 0.0563
Echinococcus multilocularis RUN 0.0019 0.0007 0.0013
Loa Loa (eye worm) hypothetical protein 0.0061 0.0115 0.0296
Loa Loa (eye worm) hypothetical protein 0.0061 0.0115 0.0296
Onchocerca volvulus 0.0031 0.0038 0.0162
Trichomonas vaginalis esterase, putative 0.0071 0.0142 0.263
Toxoplasma gondii calcium-dependent protein kinase CDPK3 0.0068 0.0134 0.0832
Loa Loa (eye worm) hypothetical protein 0.0068 0.0135 0.0347
Trypanosoma cruzi PAB1-binding protein , putative 0.0101 0.022 0.1129
Loa Loa (eye worm) hypothetical protein 0.0061 0.0115 0.0296
Trichomonas vaginalis sugar transporter, putative 0.0031 0.0038 0.0681
Loa Loa (eye worm) hypothetical protein 0.0116 0.0259 0.0671
Echinococcus granulosus Cys loop ligand gated ion channel subunit 0.0061 0.0115 0.0296
Loa Loa (eye worm) hypothetical protein 0.0031 0.0038 0.0095
Echinococcus granulosus glycine receptor subunit alpha 1 0.0061 0.0115 0.0296
Loa Loa (eye worm) jmjC domain-containing protein 0.0032 0.004 0.01
Plasmodium falciparum importin beta, putative 0.0024 0.002 0.0075
Schistosoma mansoni family S9 non-peptidase homologue (S09 family) 0.0068 0.0135 0.0133
Echinococcus multilocularis geminin 0.0678 0.1721 0.4479
Brugia malayi hypothetical protein 0.0019 0.0007 0.0048
Loa Loa (eye worm) hypothetical protein 0.0019 0.0007 0.0014
Brugia malayi jmjC domain containing protein 0.0032 0.004 0.0333
Echinococcus granulosus lamin dm0 0.0027 0.0027 0.0064
Echinococcus granulosus alpha 1A adrenergic receptor 0.0116 0.0259 0.0671
Schistosoma mansoni sugar transporter 0.0031 0.0038 0.0036
Echinococcus granulosus orexin receptor type 2 0.0116 0.0259 0.0671
Schistosoma mansoni FTZ-F1 nuclear receptor-like protein 0.0021 0.001 0.0009
Trypanosoma cruzi serine/threonine-protein phosphatase PP1, putative 0.0251 0.0609 0.3126
Loa Loa (eye worm) serine/threonine protein phosphatase PP1 isozyme 1 0.0047 0.0079 0.02
Schistosoma mansoni sugar transporter 0.0031 0.0038 0.0036
Trichomonas vaginalis myo inositol monophosphatase, putative 0.0045 0.0073 0.1332
Echinococcus multilocularis solute carrier family 22 0.0031 0.0038 0.0095
Loa Loa (eye worm) hypothetical protein 0.0033 0.0042 0.0105
Echinococcus multilocularis somatostatin receptor 0.0116 0.0259 0.0671
Brugia malayi hypothetical protein 0.0031 0.0038 0.0317
Echinococcus multilocularis calcium:calmodulin dependent protein kinase type 0.0068 0.0134 0.0344
Brugia malayi Neuronal acetylcholine receptor protein, alpha-2 chain precursor 0.0028 0.003 0.0245
Echinococcus granulosus caspase 2 0.0058 0.0107 0.0273
Loa Loa (eye worm) hypothetical protein 0.005 0.0086 0.0219
Loa Loa (eye worm) G-protein-linked acetylcholine receptor protein 2 0.0116 0.0259 0.0671
Loa Loa (eye worm) hypothetical protein 0.0068 0.0135 0.0347
Trypanosoma cruzi hypothetical protein, conserved 0.0019 0.0007 0.0037
Trichomonas vaginalis sugar transporter, putative 0.0031 0.0038 0.0681
Trichomonas vaginalis protein phosphatase-1, putative 0.021 0.0504 0.9403
Plasmodium vivax calcium-dependent protein kinase 1, putative 0.0068 0.0134 0.0549
Onchocerca volvulus 0.0027 0.0027 0.0102
Trichomonas vaginalis protein phosphatase, caeel, putative 0.021 0.0504 0.9403
Echinococcus granulosus calcium:calmodulin dependent protein kinase type 0.0068 0.0134 0.0344
Loa Loa (eye worm) serine/threonine protein phosphatase PP1-gamma catalytic subunit 0.0047 0.0079 0.02
Echinococcus granulosus nicotinic acetylcholine receptor a11 subunit 0.0061 0.0115 0.0296
Loa Loa (eye worm) hypothetical protein 0.0019 0.0007 0.0013
Echinococcus granulosus Niemann Pick C1 protein 0.0103 0.0225 0.058
Schistosoma mansoni neurotransmitter gated ion channel 0.0028 0.003 0.0028
Loa Loa (eye worm) hypothetical protein 0.0028 0.003 0.0073
Echinococcus multilocularis tumor protein p63 0.033 0.0817 0.2124
Trichomonas vaginalis conserved hypothetical protein 0.0069 0.0136 0.2519
Brugia malayi Hypothetical glycine receptor like protein T20B12.9 in chromosome III 0.0033 0.0042 0.0352
Trichomonas vaginalis chromosome transmission fidelity factor, putative 0.0019 0.0007 0.0103
Trypanosoma cruzi ubiquitin carboxyl-terminal hydrolase, putative 0.0037 0.0052 0.0269
Mycobacterium ulcerans extragenic suppressor protein SuhB 0.0045 0.0073 0.4863
Toxoplasma gondii calcium-dependent protein kinase CDPK2B 0.0068 0.0134 0.0832
Schistosoma mansoni amine GPCR 0.0116 0.0259 0.0258
Trypanosoma cruzi apurinic/apyrimidinic endonuclease, putative 0.0038 0.0057 0.029
Trypanosoma cruzi serine/threonine-protein phosphatase PP1 alpha 0.021 0.0504 0.2586
Mycobacterium leprae Probable prolyl tRNA synthetase ProS 0.0067 0.013 0.9128
Toxoplasma gondii exonuclease III APE 0.0038 0.0057 0.0344
Echinococcus granulosus calcium:calmodulin dependent protein kinase type 1 0.0068 0.0134 0.0344
Schistosoma mansoni hypothetical protein 0.0048 0.0081 0.0079
Echinococcus multilocularis lysine specific demethylase 5A 0.012 0.0269 0.0696
Leishmania major hypothetical protein, conserved 0.0101 0.022 0.1129
Echinococcus granulosus fmrfamide receptor 0.0116 0.0259 0.0671
Mycobacterium tuberculosis Probable lipase LipE 0.0071 0.0142 0.0943
Brugia malayi hypothetical protein 0.0028 0.003 0.0245
Echinococcus granulosus 7tm_1 domain containing protein 0.0116 0.0259 0.0671
Echinococcus multilocularis sterol regulatory element binding protein 0.0044 0.0072 0.0182
Leishmania major serine/threonine-protein phosphatase PP1, putative 0.0765 0.1948 1
Trypanosoma cruzi prolyl-tRNA synthetase, putative 0.0078 0.0159 0.0817
Trypanosoma brucei glucose transporter, putative 0.0069 0.0136 0.0691
Schistosoma mansoni inositol monophosphatase 0.0045 0.0073 0.0071
Schistosoma mansoni microtubule-associated protein tau 0.0728 0.1851 0.1849
Leishmania major serine/threonine-protein phosphatase PP1, putative 0.0047 0.0079 0.0404
Schistosoma mansoni lamin 0.0027 0.0027 0.0025
Mycobacterium tuberculosis Conserved protein 0.0071 0.0142 0.0943
Mycobacterium ulcerans lysyl-tRNA synthetase 0.005 0.0086 0.5832
Loa Loa (eye worm) hypothetical protein 0.0032 0.004 0.01
Brugia malayi Sugar transporter family protein 0.0222 0.0536 0.4651
Trypanosoma brucei glucose transporter, putative 0.0069 0.0136 0.0691
Brugia malayi PAS domain containing protein 0.0048 0.0081 0.0686
Schistosoma mansoni aryl hydrocarbon receptor 0.0048 0.0081 0.0079
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0135 0.0308 0.0797
Mycobacterium ulcerans esterase/lipase LipP 0.0071 0.0142 1
Mycobacterium leprae Probable lysyl-tRNA synthase LysS (lysine--tRNA ligase 1) (LysRS 1) (lysine translase) 0.0042 0.0066 0.4389
Entamoeba histolytica hypothetical protein 0.0106 0.0233 1
Brugia malayi Ser/Thr protein phosphatase family protein 0.021 0.0504 0.4374
Brugia malayi Nuclear hormone receptor family member nhr-40 0.0021 0.001 0.0075
Echinococcus granulosus RUN 0.0019 0.0007 0.0013
Trypanosoma brucei apurinic/apyrimidinic endonuclease, putative 0.0038 0.0057 0.0281
Entamoeba histolytica protein kinase, putative 0.0068 0.0134 0.5621
Echinococcus granulosus g protein linked acetylcholine receptor gar 2a 0.0116 0.0259 0.0671
Echinococcus multilocularis growth hormone secretagogue receptor type 1 0.0116 0.0259 0.0671
Schistosoma mansoni patched 1 0.0044 0.0072 0.007
Loa Loa (eye worm) hypothetical protein 0.0204 0.0487 0.1264
Trichomonas vaginalis protein phosphatase, caeel, putative 0.021 0.0504 0.9403
Plasmodium falciparum major facilitator superfamily domain-containing protein, putative 0.0031 0.0038 0.0151
Loa Loa (eye worm) hypothetical protein 0.0191 0.0455 0.118
Loa Loa (eye worm) hypothetical protein 0.0028 0.003 0.0073
Brugia malayi latrophilin 2 splice variant baaae 0.0103 0.0224 0.1939
Trichomonas vaginalis sugar transporter, putative 0.0031 0.0038 0.0681
Echinococcus multilocularis COUP TF:Svp nuclear hormone receptor 0.0021 0.001 0.0022
Loa Loa (eye worm) hypothetical protein 0.0254 0.0618 0.1606
Chlamydia trachomatis lysine--tRNA ligase 0.005 0.0086 1
Echinococcus multilocularis rhodopsin orphan GPCR 0.0116 0.0259 0.0671
Brugia malayi Neurotransmitter-gated ion-channel ligand binding domain containing protein 0.0061 0.0115 0.0989
Loa Loa (eye worm) GTP-binding regulatory protein Gs alpha-S chain 0.0135 0.0308 0.0797
Echinococcus granulosus rhodopsin orphan GPCR 0.0116 0.0259 0.0671
Trichomonas vaginalis sugar transporter, putative 0.0031 0.0038 0.0681
Schistosoma mansoni cathepsin D (A01 family) 0.0191 0.0455 0.0453
Loa Loa (eye worm) hypothetical protein 0.0051 0.009 0.023
Trichomonas vaginalis penicillin-binding protein, putative 0.0071 0.0142 0.263
Trypanosoma brucei lysyl-tRNA synthetase, putative 0.005 0.0086 0.0432
Onchocerca volvulus 0.0071 0.0142 0.0703
Onchocerca volvulus 0.0116 0.0259 0.1312
Schistosoma mansoni phd/f-box containing protein 0.0032 0.004 0.0038
Trichomonas vaginalis sugar transporter, putative 0.0031 0.0038 0.0681
Schistosoma mansoni hypothetical protein 0.0116 0.0259 0.0258
Echinococcus granulosus nicotinic acetylcholine receptor alpha subunit 0.0061 0.0115 0.0296
Brugia malayi Neurotransmitter-gated ion-channel ligand binding domain containing protein 0.0028 0.003 0.0245
Echinococcus granulosus G protein coupled receptor 139 0.0116 0.0259 0.0671
Echinococcus granulosus nibrin 0.0019 0.0007 0.0014
Brugia malayi nuclear receptor NHR-88 0.0021 0.001 0.0075
Loa Loa (eye worm) hypothetical protein 0.0068 0.0134 0.0344
Mycobacterium ulcerans sugar transporter 0.0031 0.0038 0.2288
Brugia malayi Carboxylesterase family protein 0.0405 0.1012 0.8798
Echinococcus granulosus G protein coupled 5 hydroxytryptamine receptor 0.0116 0.0259 0.0671
Echinococcus granulosus g protein coupled receptor 0.0116 0.0259 0.0671
Trichomonas vaginalis sugar transporter, putative 0.0031 0.0038 0.0681
Schistosoma mansoni hypothetical protein 0.0116 0.0259 0.0258

Activities

Activity type Activity value Assay description Source Reference
Activity (functional) Antimicrobial activity against glc7-127 allele containing Saccharomyces cerevisiae harboring cdc28-as transfected with 2 uM expression vector TEplac195 at 25 nM using deletion pool construction ChEMBL. 18622389
Activity (functional) Antimicrobial activity against glc7-129 allele containing Saccharomyces cerevisiae harboring cdc28-as transfected with 2 uM expression vector TEplac195 at 25 nM using deletion pool construction ChEMBL. 18622389
ED50 (functional) = 2.8 nM Tested for inhibition of specific [3H]- okadaic acid binding to the cytosolic fraction of mouse skin ChEMBL. No reference
IC50 (binding) > 10 mM Exogenous inhibition concentration of Serine/threonine protein phosphatase 2B (PP2B) ChEMBL. 11881984
IC50 (binding) = 0.13 nM Tested for inhibition of purified catalytic subunit of protein phosphatase-2A from human erythrocytes ChEMBL. No reference
IC50 (binding) = 0.14 nM Inhibition of Serine/threonine protein phosphatase 1 (PP1) mutants by natural toxins in D220V ChEMBL. 11881984
IC50 (binding) = 0.14 nM Inhibition of Serine/threonine protein phosphatase 1 (PP1) mutants by natural toxins in D220V ChEMBL. 11881984
IC50 (binding) = 0.2 nM Exogenous inhibition concentration of Serine/threonine protein phosphatase 2A (PP2A) ChEMBL. 11881984
IC50 (binding) = 0.2 nM Exogenous inhibition concentration of Serine/threonine protein phosphatase 2A (PP2A) ChEMBL. 11881984
IC50 (binding) = 0.3 nM Exogenous inhibition of Serine/threonine protein phosphatase 1 (PP1) ChEMBL. 11881984
IC50 (binding) = 0.3 nM Tested for inhibition against purified catalytic subunit of protein phosphatase-1 from rabbit skeletal muscle ChEMBL. No reference
IC50 (binding) = 0.4 nM Inhibition of Serine/threonine protein phosphatase 1 (PP1) mutants by natural toxins in E275R ChEMBL. 11881984
IC50 (binding) = 0.4 nM Inhibition of Serine/threonine protein phosphatase 1 (PP1) mutants by natural toxins in E275R ChEMBL. 11881984
IC50 (binding) = 0.45 nM Inhibition of Serine/threonine protein phosphatase 1 (PP1) mutants by natural toxins in wild type ChEMBL. 11881984
IC50 (binding) = 0.45 nM Inhibition of Serine/threonine protein phosphatase 1 (PP1) mutants by natural toxins in wild type ChEMBL. 11881984
IC50 (binding) = 0.5 nM Inhibitory concentration of the compound against Protein phosphatase 1 was determined; 0.5-1.0 ChEMBL. 11814804
IC50 (binding) = 1.2 nM Observed inhibition activity of the compounds against protein phosphatases 1 (PP1) ChEMBL. 9379439
IC50 (binding) = 2 nM Concentration of the compound required to inhibit the action of protein phosphatase 2A ChEMBL. 11814804
IC50 (binding) = 2.2 nM Inhibition of Serine/threonine protein phosphatase 1 (PP1) mutants by natural toxins in C127S ChEMBL. 11881984
IC50 (binding) = 2.2 nM Inhibition of Serine/threonine protein phosphatase 1 (PP1) mutants by natural toxins in C127S ChEMBL. 11881984
IC50 (binding) < 3 nM Exogenous inhibition concentration of Serine/threonine protein phosphatase 5 (PP5) ChEMBL. 11881984
IC50 (binding) = 7.3 nM Observed inhibition activity of the compounds against protein phosphatases 2A (PP2A) ChEMBL. 9379439
IC50 (binding) = 48 nM Inhibition of Serine/threonine protein phosphatase 1 (PP1) mutants by natural toxins in Y272F ChEMBL. 11881984
IC50 (binding) = 48 nM Inhibition of Serine/threonine protein phosphatase 1 (PP1) mutants by natural toxins in Y272F ChEMBL. 11881984
IC50 (binding) = 58 nM Inhibition of Serine/threonine protein phosphatase 1 (PP1) mutants by natural toxins in R96A ChEMBL. 11881984
IC50 (binding) = 58 nM Inhibition of Serine/threonine protein phosphatase 1 (PP1) mutants by natural toxins in R96A ChEMBL. 11881984
IC50 (binding) > 500 nM Inhibition of Serine/threonine protein phosphatase 1 (PP1) mutants by natural toxins in N124D ChEMBL. 11881984
IC50 (binding) > 500 nM Inhibition of Serine/threonine protein phosphatase 1 (PP1) mutants by natural toxins in H248N ChEMBL. 11881984
IC50 (binding) > 500 nM Inhibition of Serine/threonine protein phosphatase 1 (PP1) mutants by natural toxins in R221S ChEMBL. 11881984
IC50 (binding) > 500 nM Inhibition of Serine/threonine protein phosphatase 1 (PP1) mutants by natural toxins in D208A ChEMBL. 11881984
IC50 (binding) > 500 nM Inhibition of Serine/threonine protein phosphatase 1 (PP1) mutants by natural toxins in N124D ChEMBL. 11881984
IC50 (binding) > 500 nM Inhibition of Serine/threonine protein phosphatase 1 (PP1) mutants by natural toxins in H248N ChEMBL. 11881984
IC50 (binding) > 500 nM Inhibition of Serine/threonine protein phosphatase 1 (PP1) mutants by natural toxins in R221S ChEMBL. 11881984
IC50 (binding) > 500 nM Inhibition of Serine/threonine protein phosphatase 1 (PP1) mutants by natural toxins in D208A ChEMBL. 11881984
NI (binding) 0 Exogenous inhibition concentration of Serine/threonine protein phosphatase 2C (PP2C); NI means no inhibition. ChEMBL. 11881984
Potency (functional) = 0.00001413 um PUBCHEM_BIOASSAY: VP16 counterscreen qHTS for inhibitors of ROR gamma transcriptional activity. (Class of assay: confirmatory) ChEMBL. No reference
Potency (functional) = 0.0014 um PUBCHEM_BIOASSAY: qHTS for inhibitors of ROR gamma transcriptional activity. (Class of assay: confirmatory) ChEMBL. No reference
Potency (functional) = 0.0398 um PUBCHEM_BIOASSAY: qHTS Assay for Identifying the Cell-Membrane Permeable IMPase Inhibitors: Potentiation with Lithium. (Class of assay: confirmatory) [Related pubchem assays: 901 ] ChEMBL. No reference
Potency (functional) = 1 um PUBCHEM_BIOASSAY: qHTS Multiplex Assay to Identify Dual Action Probes in a Cell Model of Huntington: Cytoprotection confirmation (ATP). (Class of assay: confirmatory) [Related pubchem assays: 1482, 1471, 1688 ] ChEMBL. No reference
Potency (functional) = 1.122 um PUBCHEM_BIOASSAY: qHTS Assay Multiplex Screening to Identify Dual Action Probes in a Cell Model of Huntington: Cytoprotection (Protease release). (Class of assay: confirmatory) [Related pubchem assays: 1482, 1471, 1688 ] ChEMBL. No reference
Potency (functional) 2.2387 uM PubChem BioAssay. qHTS Assay for Inhibitors of the Human Apurinic/apyrimidinic Endonuclease 1 (APE1). (Class of assay: confirmatory) ChEMBL. No reference

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

Affected Entity Phenotypic quality Occurs in Occurs at Evidence Observed in Targets
growth (GO:0040007) decreased (PATO:0000468) epimastigote (BTO:0000409) inferred from in vitro culture assay (ECO:0000182) Trypanosoma cruzi 36321  
Annotator: millerja@u.washington.edu Comment: Association of these phenotype description with T. cruzi genes is based on amino acid sequences for 2 genes as shown in Figure 1 of referenced publication References: 10678947
growth (GO:0040007) decreased (PATO:0000468) epimastigote (BTO:0000409) inferred from in vitro culture assay (ECO:0000182) Trypanosoma cruzi 52056  
Annotator: millerja@u.washington.edu Comment: Association of these phenotype description with T. cruzi genes is based on amino acid sequences for 2 genes as shown in Figure 1 of referenced publication References: 10678947
growth (GO:0040007) decreased (PATO:0000468) epimastigote (BTO:0000409) inferred from in vitro culture assay (ECO:0000182) Trypanosoma cruzi 39753  
Annotator: millerja@u.washington.edu Comment: Association of these phenotype description with T. cruzi genes is based on amino acid sequences for 2 genes as shown in Figure 1 of referenced publication References: 10678947
growth (GO:0040007) decreased (PATO:0000468) epimastigote (BTO:0000409) inferred from in vitro culture assay (ECO:0000182) Trypanosoma cruzi 42089  
Annotator: millerja@u.washington.edu Comment: Association of these phenotype description with T. cruzi genes is based on amino acid sequences for 2 genes as shown in Figure 1 of referenced publication References: 10678947
growth (GO:0040007) decreased (PATO:0000468) epimastigote (BTO:0000409) inferred from in vitro culture assay (ECO:0000182) Trypanosoma cruzi 51588  
Annotator: millerja@u.washington.edu Comment: Association of these phenotype description with T. cruzi genes is based on amino acid sequences for 2 genes as shown in Figure 1 of referenced publication References: 10678947
growth (GO:0040007) decreased (PATO:0000468) epimastigote (BTO:0000409) inferred from in vitro culture assay (ECO:0000182) Trypanosoma cruzi 37361  
Annotator: millerja@u.washington.edu Comment: Association of these phenotype description with T. cruzi genes is based on amino acid sequences for 2 genes as shown in Figure 1 of referenced publication References: 10678947
growth (GO:0040007) decreased (PATO:0000468) epimastigote (BTO:0000409) inferred from in vitro culture assay (ECO:0000182) Trypanosoma cruzi 50922  
Annotator: millerja@u.washington.edu Comment: Association of these phenotype description with T. cruzi genes is based on amino acid sequences for 2 genes as shown in Figure 1 of referenced publication References: 10678947
growth (GO:0040007) decreased (PATO:0000468) epimastigote (BTO:0000409) inferred from in vitro culture assay (ECO:0000182) Trypanosoma cruzi 53794  
Annotator: millerja@u.washington.edu Comment: Association of these phenotype description with T. cruzi genes is based on amino acid sequences for 2 genes as shown in Figure 1 of referenced publication References: 10678947
growth (GO:0040007) decreased (PATO:0000468) epimastigote (BTO:0000409) inferred from in vitro culture assay (ECO:0000182) Trypanosoma cruzi 38295  
Annotator: millerja@u.washington.edu Comment: Association of these phenotype description with T. cruzi genes is based on amino acid sequences for 2 genes as shown in Figure 1 of referenced publication References: 10678947
catalytic activity (GO:0003824) decreased (PATO:0000468) epimastigote (BTO:0000409) inferred from enzyme inhibition (ECO:0000184) Trypanosoma cruzi 36321  
Annotator: millerja@u.washington.edu Comment: Association of these phenotype description with T. cruzi genes is based on amino acid sequences for 2 genes as shown in Figure 1 of referenced publication References: 10678947
catalytic activity (GO:0003824) decreased (PATO:0000468) epimastigote (BTO:0000409) inferred from enzyme inhibition (ECO:0000184) Trypanosoma cruzi 52056  
Annotator: millerja@u.washington.edu Comment: Association of these phenotype description with T. cruzi genes is based on amino acid sequences for 2 genes as shown in Figure 1 of referenced publication References: 10678947
catalytic activity (GO:0003824) decreased (PATO:0000468) epimastigote (BTO:0000409) inferred from enzyme inhibition (ECO:0000184) Trypanosoma cruzi 39753  
Annotator: millerja@u.washington.edu Comment: Association of these phenotype description with T. cruzi genes is based on amino acid sequences for 2 genes as shown in Figure 1 of referenced publication References: 10678947
catalytic activity (GO:0003824) decreased (PATO:0000468) epimastigote (BTO:0000409) inferred from enzyme inhibition (ECO:0000184) Trypanosoma cruzi 42089  
Annotator: millerja@u.washington.edu Comment: Association of these phenotype description with T. cruzi genes is based on amino acid sequences for 2 genes as shown in Figure 1 of referenced publication References: 10678947
catalytic activity (GO:0003824) decreased (PATO:0000468) epimastigote (BTO:0000409) inferred from enzyme inhibition (ECO:0000184) Trypanosoma cruzi 51588  
Annotator: millerja@u.washington.edu Comment: Association of these phenotype description with T. cruzi genes is based on amino acid sequences for 2 genes as shown in Figure 1 of referenced publication References: 10678947
catalytic activity (GO:0003824) decreased (PATO:0000468) epimastigote (BTO:0000409) inferred from enzyme inhibition (ECO:0000184) Trypanosoma cruzi 37361  
Annotator: millerja@u.washington.edu Comment: Association of these phenotype description with T. cruzi genes is based on amino acid sequences for 2 genes as shown in Figure 1 of referenced publication References: 10678947
catalytic activity (GO:0003824) decreased (PATO:0000468) epimastigote (BTO:0000409) inferred from enzyme inhibition (ECO:0000184) Trypanosoma cruzi 50922  
Annotator: millerja@u.washington.edu Comment: Association of these phenotype description with T. cruzi genes is based on amino acid sequences for 2 genes as shown in Figure 1 of referenced publication References: 10678947
catalytic activity (GO:0003824) decreased (PATO:0000468) epimastigote (BTO:0000409) inferred from enzyme inhibition (ECO:0000184) Trypanosoma cruzi 53794  
Annotator: millerja@u.washington.edu Comment: Association of these phenotype description with T. cruzi genes is based on amino acid sequences for 2 genes as shown in Figure 1 of referenced publication References: 10678947
catalytic activity (GO:0003824) decreased (PATO:0000468) epimastigote (BTO:0000409) inferred from enzyme inhibition (ECO:0000184) Trypanosoma cruzi 38295  
Annotator: millerja@u.washington.edu Comment: Association of these phenotype description with T. cruzi genes is based on amino acid sequences for 2 genes as shown in Figure 1 of referenced publication References: 10678947

In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
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External resources for this compound

Bibliographic References

7 literature references were collected for this gene.

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