Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Brugia malayi | Nuclear hormone receptor-like 1 | 0.0035 | 0.0328 | 0.0369 |
Echinococcus multilocularis | nuclear receptor 2DBD gamma | 0.0066 | 0.1459 | 0.2342 |
Loa Loa (eye worm) | hypothetical protein | 0.0066 | 0.1459 | 0.1732 |
Schistosoma mansoni | nuclear hormone receptor | 0.0066 | 0.1459 | 0.2342 |
Mycobacterium tuberculosis | Probable nitrite reductase [NAD(P)H] large subunit [FAD flavoprotein] NirB | 0.0125 | 0.3603 | 0.7608 |
Echinococcus granulosus | nuclear receptor subfamily 1 group D | 0.0035 | 0.0328 | 0.0572 |
Echinococcus multilocularis | thioredoxin glutathione reductase | 0.0055 | 0.1052 | 0.1682 |
Schistosoma mansoni | hepatocyte nuclear factor 4-alpha (hnf-4-alpha) | 0.0031 | 0.0192 | 0.0284 |
Schistosoma mansoni | nuclear hormone receptor superfamily protein-related | 0.0031 | 0.0192 | 0.0284 |
Brugia malayi | Nuclear hormone receptor-like 1 | 0.0066 | 0.1459 | 0.1715 |
Loa Loa (eye worm) | nuclear hormone receptor-like 1 | 0.0035 | 0.0328 | 0.0389 |
Brugia malayi | tailless protein | 0.0031 | 0.0192 | 0.0208 |
Onchocerca volvulus | 0.0072 | 0.1674 | 1 | |
Echinococcus multilocularis | Mitotic checkpoint protein PRCC, C terminal | 0.013 | 0.3773 | 0.6104 |
Trichomonas vaginalis | fructose-bisphosphate aldolase, putative | 0.0301 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0035 | 0.0328 | 0.0389 |
Mycobacterium tuberculosis | Dihydrolipoamide dehydrogenase LpdC (lipoamide reductase (NADH)) (lipoyl dehydrogenase) (dihydrolipoyl dehydrogenase) (diaphoras | 0.0139 | 0.411 | 0.9119 |
Loa Loa (eye worm) | nuclear receptor NHR-67 | 0.0031 | 0.0192 | 0.0228 |
Mycobacterium tuberculosis | NAD(P)H quinone reductase LpdA | 0.0139 | 0.411 | 0.9119 |
Brugia malayi | orphan nuclear receptor NR2E1 | 0.0031 | 0.0192 | 0.0208 |
Schistosoma mansoni | jun-related protein | 0.0074 | 0.1766 | 0.2841 |
Loa Loa (eye worm) | hypothetical protein | 0.0066 | 0.1459 | 0.1732 |
Treponema pallidum | fructose-bisphosphate aldolase | 0.0301 | 1 | 0.5 |
Schistosoma mansoni | nuclear hormone receptor | 0.0031 | 0.0192 | 0.0284 |
Schistosoma mansoni | nuclear hormone receptor nor-1/nor-2 | 0.0066 | 0.1459 | 0.2342 |
Schistosoma mansoni | zinc finger protein | 0.0031 | 0.0192 | 0.0284 |
Loa Loa (eye worm) | hypothetical protein | 0.0031 | 0.0192 | 0.0228 |
Echinococcus granulosus | solute carrier family 2 facilitated glucose | 0.0114 | 0.3202 | 0.5868 |
Echinococcus multilocularis | General substrate transporter | 0.0098 | 0.2619 | 0.4229 |
Brugia malayi | ecdysone receptor | 0.0031 | 0.0192 | 0.0208 |
Echinococcus multilocularis | thyroid hormone receptor alpha | 0.0195 | 0.617 | 1 |
Brugia malayi | glutathione reductase | 0.0055 | 0.1052 | 0.1231 |
Schistosoma mansoni | nuclear receptor | 0.0031 | 0.0192 | 0.0284 |
Echinococcus multilocularis | Nuclear hormone receptor HR96 | 0.0031 | 0.0192 | 0.0284 |
Schistosoma mansoni | transcription factor LCR-F1 | 0.0035 | 0.0346 | 0.0533 |
Schistosoma mansoni | thyroid hormone receptor | 0.0195 | 0.617 | 1 |
Echinococcus multilocularis | nuclear receptor nhr 48 | 0.0031 | 0.0192 | 0.0284 |
Echinococcus multilocularis | Basic leucine zipper (bZIP) transcription | 0.0035 | 0.0346 | 0.0533 |
Schistosoma mansoni | nuclear receptor nhr-48 | 0.0031 | 0.0192 | 0.0284 |
Plasmodium vivax | hexose transporter | 0.0114 | 0.3202 | 1 |
Loa Loa (eye worm) | DR-78 | 0.0031 | 0.0192 | 0.0228 |
Brugia malayi | hypothetical protein | 0.0035 | 0.0328 | 0.0369 |
Trypanosoma brucei | tyrosyl-DNA Phosphodiesterase (Tdp1), putative | 0.0076 | 0.1841 | 1 |
Echinococcus granulosus | Basic leucine zipper bZIP transcription | 0.0035 | 0.0346 | 0.0605 |
Leishmania major | tyrosyl-DNA phosphodiesterase 1 | 0.0076 | 0.1841 | 1 |
Brugia malayi | nuclear receptor RXR | 0.0035 | 0.0328 | 0.0369 |
Giardia lamblia | Fructose-bisphosphate aldolase | 0.0301 | 1 | 0.5 |
Loa Loa (eye worm) | hypothetical protein | 0.0066 | 0.1459 | 0.1732 |
Loa Loa (eye worm) | hypothetical protein | 0.0066 | 0.1459 | 0.1732 |
Brugia malayi | steroid hormone receptor | 0.0066 | 0.1459 | 0.1715 |
Echinococcus granulosus | Basic leucine zipper bZIP transcription factor | 0.0091 | 0.2389 | 0.4371 |
Loa Loa (eye worm) | hypothetical protein | 0.0066 | 0.1459 | 0.1732 |
Loa Loa (eye worm) | nuclear receptor nhr-7B | 0.0031 | 0.0192 | 0.0228 |
Schistosoma mansoni | retinoic acid receptor RXR | 0.0175 | 0.5443 | 0.8819 |
Trichomonas vaginalis | fructose-bisphosphate aldolase, putative | 0.0301 | 1 | 1 |
Echinococcus granulosus | solute carrier family 2 facilitated glucose | 0.0114 | 0.3202 | 0.5868 |
Mycobacterium tuberculosis | Probable membrane NADH dehydrogenase NdhA | 0.0125 | 0.3603 | 0.7608 |
Brugia malayi | follicle stimulating hormone receptor | 0.0257 | 0.8423 | 1 |
Brugia malayi | nuclear hormone receptor family member odr-7 | 0.0031 | 0.0192 | 0.0208 |
Toxoplasma gondii | facilitative glucose transporter GT1 | 0.0114 | 0.3202 | 1 |
Brugia malayi | Nuclear hormone receptor family member nhr-25 | 0.0066 | 0.1459 | 0.1715 |
Brugia malayi | Nuclear hormone receptor-like 1 | 0.0035 | 0.0328 | 0.0369 |
Brugia malayi | Steroid receptor seven-up type 2 | 0.0066 | 0.1459 | 0.1715 |
Echinococcus granulosus | nuclear receptor subfamily 4 group A | 0.0031 | 0.0192 | 0.0322 |
Brugia malayi | Nuclear hormone receptor E75 | 0.0031 | 0.0192 | 0.0208 |
Echinococcus granulosus | Mitotic checkpoint protein PRCC C terminal | 0.013 | 0.3773 | 0.6921 |
Schistosoma mansoni | Tr4/Tr2 (homologue) | 0.0066 | 0.1459 | 0.2342 |
Onchocerca volvulus | Steroid hormone receptor family member cnr14 homolog | 0.0066 | 0.1459 | 0.8697 |
Brugia malayi | Nuclear hormone receptor family member nhr-19 | 0.0066 | 0.1459 | 0.1715 |
Echinococcus granulosus | thioredoxin glutathione reductase | 0.0055 | 0.1052 | 0.1907 |
Echinococcus multilocularis | jun protein | 0.0091 | 0.2389 | 0.3855 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-41 | 0.0066 | 0.1459 | 0.1732 |
Echinococcus granulosus | FTZ F1 alpha | 0.0066 | 0.1459 | 0.2656 |
Entamoeba histolytica | tyrosyl-DNA phosphodiesterase, putative | 0.0076 | 0.1841 | 0.1549 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-40 | 0.0066 | 0.1459 | 0.1732 |
Brugia malayi | hypothetical protein | 0.0031 | 0.0192 | 0.0208 |
Loa Loa (eye worm) | hypothetical protein | 0.0035 | 0.0328 | 0.0389 |
Brugia malayi | nuclear hormone receptor | 0.0066 | 0.1459 | 0.1715 |
Leishmania major | trypanothione reductase | 0.0055 | 0.1052 | 0.4727 |
Echinococcus multilocularis | Nuclear hormone receptor family member nhr 41 | 0.0066 | 0.1459 | 0.2342 |
Loa Loa (eye worm) | hypothetical protein | 0.0031 | 0.0192 | 0.0228 |
Echinococcus multilocularis | tyrosyl DNA phosphodiesterase 1 | 0.0076 | 0.1841 | 0.2963 |
Loa Loa (eye worm) | hypothetical protein | 0.0089 | 0.2298 | 0.2728 |
Schistosoma mansoni | hypothetical protein | 0.0074 | 0.1766 | 0.2841 |
Schistosoma mansoni | RAR-like nuclear receptor | 0.0066 | 0.1459 | 0.2342 |
Schistosoma mansoni | coup transcription factor | 0.0066 | 0.1459 | 0.2342 |
Echinococcus granulosus | COUP TF:Svp nuclear hormone receptor | 0.0066 | 0.1459 | 0.2656 |
Echinococcus granulosus | Nuclear hormone receptor family member nhr 41 | 0.0066 | 0.1459 | 0.2656 |
Onchocerca volvulus | 0.0031 | 0.0192 | 0.1054 | |
Schistosoma mansoni | hypothetical protein | 0.013 | 0.3773 | 0.6104 |
Brugia malayi | Nuclear hormone receptor E75 | 0.0031 | 0.0192 | 0.0208 |
Brugia malayi | Tyrosyl-DNA phosphodiesterase family protein | 0.0076 | 0.1841 | 0.2169 |
Loa Loa (eye worm) | hypothetical protein | 0.0031 | 0.0192 | 0.0228 |
Loa Loa (eye worm) | hypothetical protein | 0.0066 | 0.1459 | 0.1732 |
Mycobacterium tuberculosis | Probable dehydrogenase | 0.0125 | 0.3603 | 0.7608 |
Loa Loa (eye worm) | hypothetical protein | 0.0031 | 0.0192 | 0.0228 |
Onchocerca volvulus | Bile acid receptor homolog | 0.0066 | 0.1459 | 0.8697 |
Echinococcus multilocularis | FTZ F1 alpha | 0.0066 | 0.1459 | 0.2342 |
Onchocerca volvulus | 0.0066 | 0.1459 | 0.8697 | |
Echinococcus multilocularis | solute carrier family 2, facilitated glucose | 0.0114 | 0.3202 | 0.5175 |
Brugia malayi | Nuclear hormone receptor family member nhr-40 | 0.0066 | 0.1459 | 0.1715 |
Loa Loa (eye worm) | hypothetical protein | 0.0026 | 0.0017 | 0.0021 |
Brugia malayi | hypothetical protein | 0.0031 | 0.0192 | 0.0208 |
Schistosoma mansoni | photoreceptor-specific nuclear receptor related | 0.0066 | 0.1459 | 0.2342 |
Onchocerca volvulus | Protein ultraspiracle homolog | 0.0066 | 0.1459 | 0.8697 |
Loa Loa (eye worm) | intermediate filament tail domain-containing protein | 0.0026 | 0.0017 | 0.0021 |
Mycobacterium ulcerans | fructose-bisphosphate aldolase | 0.0147 | 0.4405 | 0.5 |
Echinococcus multilocularis | solute carrier family 2 facilitated glucose | 0.0114 | 0.3202 | 0.5175 |
Brugia malayi | Nuclear hormone receptor family member nhr-14 | 0.0066 | 0.1459 | 0.1715 |
Trichomonas vaginalis | fructose-bisphosphate aldolase, putative | 0.0301 | 1 | 1 |
Brugia malayi | nuclear receptor NHR-88 | 0.0066 | 0.1459 | 0.1715 |
Brugia malayi | nuclear receptor RXR | 0.0031 | 0.0192 | 0.0208 |
Mycobacterium leprae | Probable fructose bisphosphate aldolase Fba | 0.0147 | 0.4405 | 1 |
Echinococcus granulosus | Nuclear hormone receptor HR96 | 0.0031 | 0.0192 | 0.0322 |
Brugia malayi | Nuclear hormone receptor family member nhr-25 | 0.0066 | 0.1459 | 0.1715 |
Loa Loa (eye worm) | hypothetical protein | 0.0031 | 0.0192 | 0.0228 |
Brugia malayi | Nuclear hormone receptor family member nhr-49 | 0.0066 | 0.1459 | 0.1715 |
Schistosoma mansoni | nuclear receptor 2DBD-gamma | 0.0066 | 0.1459 | 0.2342 |
Mycobacterium tuberculosis | Putative ferredoxin reductase | 0.0125 | 0.3603 | 0.7608 |
Brugia malayi | hypothetical protein | 0.0035 | 0.0346 | 0.039 |
Echinococcus multilocularis | Nuclear hormone receptor HR96 | 0.0031 | 0.0192 | 0.0284 |
Echinococcus granulosus | solute carrier family 2 facilitated glucose | 0.0114 | 0.3202 | 0.5868 |
Brugia malayi | conserved hypotetical protein | 0.0031 | 0.0192 | 0.0208 |
Schistosoma mansoni | thyroid hormone receptor | 0.0195 | 0.617 | 1 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-14 | 0.0066 | 0.1459 | 0.1732 |
Echinococcus multilocularis | nuclear receptor subfamily 4 group A | 0.0031 | 0.0192 | 0.0284 |
Brugia malayi | ecdysteroid receptor | 0.0066 | 0.1459 | 0.1715 |
Echinococcus multilocularis | solute carrier family 2 facilitated glucose | 0.0114 | 0.3202 | 0.5175 |
Schistosoma mansoni | tyrosyl-DNA phosphodiesterase | 0.0076 | 0.1841 | 0.2963 |
Brugia malayi | Thioredoxin reductase | 0.0055 | 0.1052 | 0.1231 |
Schistosoma mansoni | nuclear hormone receptor | 0.0031 | 0.0192 | 0.0284 |
Brugia malayi | nuclear hormone receptor | 0.0031 | 0.0192 | 0.0208 |
Trypanosoma cruzi | trypanothione reductase, putative | 0.0055 | 0.1052 | 0.4727 |
Echinococcus multilocularis | nuclear receptor 2DBD gamma | 0.0066 | 0.1459 | 0.2342 |
Echinococcus granulosus | FTZ F1 nuclear receptor protein | 0.0066 | 0.1459 | 0.2656 |
Echinococcus multilocularis | nuclear receptor subfamily 1 group D | 0.0035 | 0.0328 | 0.0504 |
Echinococcus granulosus | retinoic acid receptor rxr beta a | 0.0175 | 0.5443 | 1 |
Loa Loa (eye worm) | nuclear hormone receptor | 0.0031 | 0.0192 | 0.0228 |
Mycobacterium tuberculosis | Probable fructose-bisphosphate aldolase Fba | 0.0147 | 0.4405 | 1 |
Trichomonas vaginalis | fructose-bisphosphate aldolase, putative | 0.0301 | 1 | 1 |
Echinococcus granulosus | General substrate transporter | 0.0098 | 0.2619 | 0.4795 |
Echinococcus multilocularis | FTZ F1 nuclear receptor protein | 0.0066 | 0.1459 | 0.2342 |
Plasmodium falciparum | hexose transporter | 0.0114 | 0.3202 | 1 |
Brugia malayi | nuclear receptor subfamily 1, group D, member 1, putative | 0.0031 | 0.0192 | 0.0208 |
Loa Loa (eye worm) | glutathione reductase | 0.0055 | 0.1052 | 0.1249 |
Schistosoma mansoni | hypothetical protein | 0.0035 | 0.0346 | 0.0533 |
Entamoeba histolytica | fructose-1,6-bisphosphate aldolase, putative | 0.0301 | 1 | 1 |
Echinococcus granulosus | thyroid hormone receptor alpha | 0.0031 | 0.0192 | 0.0322 |
Echinococcus granulosus | jun protein | 0.0091 | 0.2389 | 0.4371 |
Echinococcus granulosus | nuclear receptor nhr 48 | 0.0031 | 0.0192 | 0.0322 |
Loa Loa (eye worm) | follicle stimulating hormone receptor | 0.0257 | 0.8423 | 1 |
Brugia malayi | nuclear receptor NHR-67 | 0.0031 | 0.0192 | 0.0208 |
Echinococcus multilocularis | COUP TF:Svp nuclear hormone receptor | 0.0066 | 0.1459 | 0.2342 |
Loa Loa (eye worm) | hypothetical protein | 0.0035 | 0.0328 | 0.0389 |
Echinococcus multilocularis | retinoic acid receptor rxr beta a retinoic acid receptor rxr alpha a retinoic acid receptor rxr alpha | 0.0141 | 0.4177 | 0.676 |
Loa Loa (eye worm) | steroid hormone receptor | 0.0066 | 0.1459 | 0.1732 |
Brugia malayi | Nuclear hormone receptor family member nhr-3 | 0.0066 | 0.1459 | 0.1715 |
Brugia malayi | Nuclear hormone receptor family member nhr-19 | 0.0066 | 0.1459 | 0.1715 |
Onchocerca volvulus | Nuclear receptor subfamily 6 group A member 1 homolog | 0.0031 | 0.0192 | 0.1054 |
Brugia malayi | hypothetical protein | 0.0072 | 0.1674 | 0.1971 |
Trichomonas vaginalis | fructose-bisphosphate aldolase, putative | 0.0301 | 1 | 1 |
Schistosoma mansoni | hypothetical protein | 0.0114 | 0.3202 | 0.5175 |
Brugia malayi | bZIP transcription factor family protein | 0.0091 | 0.2389 | 0.2821 |
Trypanosoma cruzi | tyrosyl-DNA Phosphodiesterase (Tdp1), putative | 0.0076 | 0.1841 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0031 | 0.0192 | 0.0228 |
Mycobacterium tuberculosis | Probable oxidoreductase | 0.0139 | 0.411 | 0.9119 |
Mycobacterium leprae | DIHYDROLIPOAMIDE DEHYDROGENASE LPD (LIPOAMIDE REDUCTASE (NADH)) (LIPOYL DEHYDROGENASE) (DIHYDROLIPOYL DEHYDROGENASE) (DIAPHORASE | 0.0139 | 0.411 | 0.6318 |
Schistosoma mansoni | ecdysone-induced protein 78c (dr-78) | 0.0035 | 0.0328 | 0.0504 |
Loa Loa (eye worm) | hypothetical protein | 0.0031 | 0.0192 | 0.0228 |
Brugia malayi | Nuclear hormone receptor family member nhr-31 | 0.0066 | 0.1459 | 0.1715 |
Brugia malayi | Sugar transporter family protein | 0.0114 | 0.3202 | 0.3788 |
Echinococcus granulosus | nuclear receptor 2DBD gamma | 0.0031 | 0.0192 | 0.0322 |
Loa Loa (eye worm) | hypothetical protein | 0.0035 | 0.0328 | 0.0389 |
Echinococcus multilocularis | solute carrier family 2 facilitated glucose | 0.0114 | 0.3202 | 0.5175 |
Loa Loa (eye worm) | hypothetical protein | 0.0031 | 0.0192 | 0.0228 |
Loa Loa (eye worm) | hypothetical protein | 0.0031 | 0.0192 | 0.0228 |
Brugia malayi | nuclear hormone receptor family member nhr-6 | 0.0031 | 0.0192 | 0.0208 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0114 | 0.3202 | 0.2958 |
Echinococcus granulosus | nuclear receptor 2DBD gamma | 0.0066 | 0.1459 | 0.2656 |
Trichomonas vaginalis | fructose-bisphosphate aldolase, putative | 0.0301 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0035 | 0.0328 | 0.0389 |
Echinococcus granulosus | transcription factor Dp 1 | 0.0044 | 0.067 | 0.1203 |
Schistosoma mansoni | steroid hormone receptor ad4bp | 0.0066 | 0.1459 | 0.2342 |
Mycobacterium tuberculosis | Probable reductase | 0.0125 | 0.3603 | 0.7608 |
Loa Loa (eye worm) | thioredoxin reductase | 0.0055 | 0.1052 | 0.1249 |
Schistosoma mansoni | nuclear receptor | 0.0031 | 0.0192 | 0.0284 |
Onchocerca volvulus | 0.0031 | 0.0192 | 0.1054 | |
Echinococcus multilocularis | hepatocyte nuclear factor 4 alpha | 0.0066 | 0.1459 | 0.2342 |
Schistosoma mansoni | glucose transport protein | 0.0114 | 0.3202 | 0.5175 |
Loa Loa (eye worm) | intermediate filament protein | 0.0026 | 0.0017 | 0.0021 |
Echinococcus granulosus | tyrosyl DNA phosphodiesterase 1 | 0.0076 | 0.1841 | 0.336 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-49 | 0.0066 | 0.1459 | 0.1732 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-1 | 0.0066 | 0.1459 | 0.1732 |
Echinococcus granulosus | nuclear receptor 2DBD gamma | 0.0066 | 0.1459 | 0.2656 |
Schistosoma mansoni | glucose transport protein | 0.0114 | 0.3202 | 0.5175 |
Loa Loa (eye worm) | hypothetical protein | 0.0031 | 0.0192 | 0.0228 |
Loa Loa (eye worm) | tyrosyl-DNA phosphodiesterase | 0.0076 | 0.1841 | 0.2185 |
Trichomonas vaginalis | fructose-bisphosphate aldolase, putative | 0.0301 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0031 | 0.0192 | 0.0228 |
Echinococcus granulosus | solute carrier family 2 facilitated glucose | 0.0114 | 0.3202 | 0.5868 |
Trichomonas vaginalis | fructose-bisphosphate aldolase, putative | 0.0301 | 1 | 1 |
Loa Loa (eye worm) | nuclear Hormone Receptor family member | 0.0066 | 0.1459 | 0.1732 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-31 | 0.0066 | 0.1459 | 0.1732 |
Mycobacterium tuberculosis | Probable NADH dehydrogenase Ndh | 0.0125 | 0.3603 | 0.7608 |
Echinococcus granulosus | Nuclear hormone receptor HR96 | 0.0031 | 0.0192 | 0.0322 |
Schistosoma mansoni | retinoid-x-receptor (RXR) | 0.0066 | 0.1459 | 0.2342 |
Schistosoma mansoni | FTZ-F1 nuclear receptor-like protein | 0.0066 | 0.1459 | 0.2342 |
Schistosoma mansoni | glucose transport protein | 0.0114 | 0.3202 | 0.5175 |
Loa Loa (eye worm) | hypothetical protein | 0.0066 | 0.1459 | 0.1732 |
Brugia malayi | nuclear receptor NHR-88 | 0.0031 | 0.0192 | 0.0208 |
Loa Loa (eye worm) | sugar transporter | 0.0114 | 0.3202 | 0.3801 |
Echinococcus multilocularis | Basic leucine zipper (bZIP) transcription factor | 0.0091 | 0.2389 | 0.3855 |
Onchocerca volvulus | Nuclear receptor subfamily 6 group A member 1 homolog | 0.0031 | 0.0192 | 0.1054 |
Echinococcus multilocularis | transcription factor Dp 1 | 0.0044 | 0.067 | 0.1061 |
Loa Loa (eye worm) | hypothetical protein | 0.0066 | 0.1459 | 0.1732 |
Brugia malayi | photoreceptor-specific nuclear receptor | 0.0066 | 0.1459 | 0.1715 |
Brugia malayi | Nuclear hormone receptor family member nhr-41 | 0.0066 | 0.1459 | 0.1715 |
Trypanosoma brucei | trypanothione reductase | 0.0055 | 0.1052 | 0.4727 |
Echinococcus multilocularis | ecdysone induced protein 78C | 0.0066 | 0.1459 | 0.2342 |
Loa Loa (eye worm) | hypothetical protein | 0.0031 | 0.0192 | 0.0228 |
Echinococcus granulosus | ecdysone induced protein 78C | 0.0066 | 0.1459 | 0.2656 |
Brugia malayi | Ligand-binding domain of nuclear hormone receptor family protein | 0.0066 | 0.1459 | 0.1715 |
Echinococcus multilocularis | nuclear receptor 2DBD gamma | 0.0031 | 0.0192 | 0.0284 |
Loa Loa (eye worm) | hypothetical protein | 0.0031 | 0.0192 | 0.0228 |
Brugia malayi | Nuclear hormone receptor family member nhr-1 | 0.0066 | 0.1459 | 0.1715 |
Trypanosoma cruzi | tyrosyl-DNA Phosphodiesterase (Tdp1), putative | 0.0076 | 0.1841 | 1 |
Echinococcus granulosus | hepatocyte nuclear factor 4 alpha | 0.0066 | 0.1459 | 0.2656 |
Brugia malayi | hypothetical protein | 0.0035 | 0.0328 | 0.0369 |
Schistosoma mansoni | retinoid-x-receptor (RXR) | 0.0035 | 0.0328 | 0.0504 |
Brugia malayi | Ligand-binding domain of nuclear hormone receptor family protein | 0.0066 | 0.1459 | 0.1715 |
Activity type | Activity value | Assay description | Source | Reference |
---|---|---|---|---|
Activity (binding) | < 2 dose ratio | In vitro inhibition of substance P induced contractions of the guinea pig ileum at 5 uM. | ChEMBL. | 2433443 |
Activity (binding) | = 2.3 dose ratio | In vitro inhibition of substance P induced contractions of the guinea pig ileum at 10 uM. | ChEMBL. | 2433443 |
Activity (binding) | = 3.6 dose ratio | In vitro inhibition of substance P (6-11) hexapeptide induced contractions of the guinea pig ileum at 5 uM. | ChEMBL. | 2433443 |
Activity (binding) | = 15.3 dose ratio | In vitro inhibition of substance P (6-11) hexapeptide induced contractions of the guinea pig ileum at 10 uM. | ChEMBL. | 2433443 |
Change in amplitude response (functional) | = -74 % | Antagonistic activity of the compound against Substance P(6-11) receptor in rat spinal cord at concentration of 50 uM. | ChEMBL. | 2433443 |
Change in amplitude response (functional) | = -54 % | Antagonistic activity of the compound against Substance P receptor in rat spinal cord at concentration of 50 uM. | ChEMBL. | 2433443 |
Change in amplitude response (functional) | = -43 % | Antagonistic activity of the compound against Glutamate receptor in rat spinal cord at concentration of 50 uM. | ChEMBL. | 2433443 |
Change in amplitude response (functional) | = -28 % | Antagonistic activity of the compound against Substance P(6-11) receptor in rat spinal cord at concentration of 5 uM. | ChEMBL. | 2433443 |
Change in amplitude response (functional) | = 46 % | Antagonistic activity of the compound against Substance P receptor in rat spinal cord at concentration of 5 uM. | ChEMBL. | 2433443 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.
1 literature reference was collected for this gene.