Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Trypanosoma cruzi | ISWI complex protein | 0.0004 | 0 | 0.5 |
Trypanosoma brucei | ISWI complex protein | 0.0004 | 0 | 0.5 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0008 | 0.0603 | 1 |
Trichomonas vaginalis | chromodomain-helicase-DNA-binding protein, putative | 0.0004 | 0.0082 | 0.1363 |
Onchocerca volvulus | 0.0033 | 0.4439 | 0.5 | |
Plasmodium falciparum | zinc finger protein, putative | 0.0004 | 0.0064 | 0.5 |
Echinococcus multilocularis | guanine nucleotide binding protein G(s) subunit | 0.0053 | 0.7379 | 1 |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.0053 | 0.7379 | 0.7362 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0008 | 0.0603 | 1 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0008 | 0.0603 | 1 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0008 | 0.0603 | 1 |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.0053 | 0.7379 | 0.7362 |
Trichomonas vaginalis | chromodomain helicase DNA binding protein, putative | 0.0008 | 0.0603 | 1 |
Schistosoma mansoni | mixed-lineage leukemia protein mll | 0.0008 | 0.0711 | 0.0651 |
Echinococcus multilocularis | cpg binding protein | 0.0035 | 0.4722 | 0.6015 |
Echinococcus granulosus | histone lysine N methyltransferase MLL3 | 0.001 | 0.1014 | 0.0453 |
Echinococcus granulosus | guanine nucleotide binding protein Gs subunit | 0.0053 | 0.7379 | 1 |
Echinococcus granulosus | cpg binding protein | 0.0035 | 0.4722 | 0.6015 |
Loa Loa (eye worm) | CXXC zinc finger family protein | 0.0033 | 0.4439 | 0.5381 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0008 | 0.0603 | 1 |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.0053 | 0.7379 | 0.7362 |
Brugia malayi | GTP-binding regulatory protein Gs alpha-S chain, putative | 0.0053 | 0.7379 | 1 |
Schistosoma mansoni | mixed-lineage leukemia protein mll | 0.0005 | 0.0191 | 0.0127 |
Trichomonas vaginalis | chromodomain helicase DNA binding protein, putative | 0.0008 | 0.0603 | 1 |
Trichomonas vaginalis | chromodomain helicase DNA binding protein, putative | 0.0008 | 0.0603 | 1 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0008 | 0.0603 | 1 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0008 | 0.0603 | 1 |
Entamoeba histolytica | hypothetical protein | 0.0004 | 0.0064 | 0.5 |
Brugia malayi | CXXC zinc finger family protein | 0.0033 | 0.4439 | 0.5396 |
Echinococcus multilocularis | histone lysine N methyltransferase MLL3 | 0.001 | 0.1014 | 0.0453 |
Trichomonas vaginalis | chromodomain helicase DNA binding protein, putative | 0.0008 | 0.0603 | 1 |
Echinococcus multilocularis | guanine nucleotide binding protein G(s) subunit | 0.0053 | 0.7379 | 1 |
Schistosoma mansoni | cpg binding protein | 0.0035 | 0.4722 | 0.4688 |
Schistosoma mansoni | cpg binding protein | 0.0033 | 0.4439 | 0.4403 |
Trichomonas vaginalis | chromodomain-helicase-DNA-binding protein, putative | 0.0008 | 0.0603 | 1 |
Trichomonas vaginalis | helicase, putative | 0.0008 | 0.0603 | 1 |
Trichomonas vaginalis | chromodomain helicase DNA binding protein, putative | 0.0008 | 0.0603 | 1 |
Toxoplasma gondii | histone lysine methyltransferase SET1 | 0.0063 | 0.8876 | 0.5 |
Loa Loa (eye worm) | GTP-binding regulatory protein Gs alpha-S chain | 0.0053 | 0.7379 | 1 |
Trichomonas vaginalis | chromodomain helicase DNA binding protein, putative | 0.0008 | 0.0603 | 1 |
Trichomonas vaginalis | chromodomain-helicase-DNA-binding protein, putative | 0.0008 | 0.0603 | 1 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0008 | 0.0603 | 1 |
Echinococcus granulosus | guanine nucleotide binding protein Gs subunit | 0.0053 | 0.7379 | 1 |
Trichomonas vaginalis | hypothetical protein | 0.0004 | 0.0082 | 0.1363 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0008 | 0.0603 | 1 |
Schistosoma mansoni | cpg binding protein | 0.0035 | 0.4722 | 0.4688 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0004 | 0.0082 | 0.1363 |
Activity type | Activity value | Assay description | Source | Reference |
---|---|---|---|---|
GSTCP activity (binding) | 0 | Binding affinity for glutamate-stimulated TCP binding site of N-methyl-D-aspartate glutamate receptor from rat brain by using [3H]-TCP as radioligand; Antagonist | ChEMBL. | 2145436 |
IC50 (binding) | = 48 uM | Inhibition of N-methyl-D-aspartate glutamate receptor by using [3H]-CPP as a radioligand from the rat cortical membranes. | ChEMBL. | 2145436 |
IC50 (binding) | = 48 uM | Ability to displace [3H]-CPP from NMDA receptor in rat brain membrane | ChEMBL. | 1533422 |
IC50 (binding) | = 48 uM | Displacement of [3H]-CPP from N-methyl-D-aspartate glutamate receptor in rat brain membrane | ChEMBL. | 1533422 |
IC50 (binding) | = 48 uM | Inhibition of N-methyl-D-aspartate glutamate receptor by using [3H]-CPP as a radioligand from the rat cortical membranes. | ChEMBL. | 2145436 |
IC50 (binding) | = 48 uM | Ability to displace [3H]-CPP from NMDA receptor in rat brain membrane | ChEMBL. | 1533422 |
IC50 (binding) | = 48 uM | Displacement of [3H]-CPP from N-methyl-D-aspartate glutamate receptor in rat brain membrane | ChEMBL. | 1533422 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.
2 literature references were collected for this gene.