Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Loa Loa (eye worm) | steroid hormone receptor | 0.0222 | 0.5835 | 0.5855 |
Loa Loa (eye worm) | hypothetical protein | 0.0222 | 0.5835 | 0.5855 |
Schistosoma mansoni | lipoxygenase | 0.0081 | 0.1244 | 0.1248 |
Onchocerca volvulus | Bile acid receptor homolog | 0.0222 | 0.5835 | 1 |
Echinococcus granulosus | tyrosine kinase | 0.0311 | 0.872 | 0.8681 |
Brugia malayi | hypothetical protein | 0.0105 | 0.2017 | 0.2024 |
Echinococcus multilocularis | tyrosine protein kinase Fgr | 0.0349 | 0.9966 | 1 |
Schistosoma mansoni | nuclear hormone receptor superfamily protein-related | 0.0105 | 0.2017 | 0.2024 |
Entamoeba histolytica | protein kinase, putative | 0.0093 | 0.1646 | 0.1894 |
Schistosoma mansoni | growth factor receptor-bound protein | 0.0078 | 0.1131 | 0.1135 |
Brugia malayi | Protein kinase domain containing protein | 0.0052 | 0.0291 | 0.0292 |
Brugia malayi | Nuclear hormone receptor family member nhr-41 | 0.0222 | 0.5835 | 0.5855 |
Schistosoma mansoni | nuclear receptor nhr-48 | 0.0105 | 0.2017 | 0.2024 |
Brugia malayi | hypothetical protein | 0.0117 | 0.2426 | 0.2434 |
Brugia malayi | hypothetical protein | 0.0117 | 0.2426 | 0.2434 |
Schistosoma mansoni | tyrosine kinase | 0.0149 | 0.3453 | 0.3465 |
Echinococcus granulosus | FTZ F1 nuclear receptor protein | 0.0222 | 0.5835 | 0.571 |
Loa Loa (eye worm) | nuclear hormone receptor | 0.0105 | 0.2017 | 0.2024 |
Loa Loa (eye worm) | hypothetical protein | 0.0222 | 0.5835 | 0.5855 |
Echinococcus multilocularis | rac serine:threonine kinase | 0.0063 | 0.067 | 0.0391 |
Schistosoma mansoni | tyrosine kinase | 0.009 | 0.1537 | 0.1543 |
Onchocerca volvulus | Nuclear receptor subfamily 6 group A member 1 homolog | 0.0105 | 0.2017 | 0.3113 |
Echinococcus multilocularis | 0.0079 | 0.1192 | 0.0932 | |
Entamoeba histolytica | protein kinase, putative | 0.0271 | 0.7442 | 1 |
Loa Loa (eye worm) | TK/INSR protein kinase | 0.0093 | 0.1635 | 0.164 |
Loa Loa (eye worm) | nuclear receptor NHR-67 | 0.0105 | 0.2017 | 0.2024 |
Echinococcus granulosus | tyrosine kinase|tyrosine protein kinase Fyn | 0.0311 | 0.872 | 0.8681 |
Brugia malayi | Nuclear hormone receptor E75 | 0.0105 | 0.2017 | 0.2024 |
Loa Loa (eye worm) | AGC/AKT protein kinase | 0.0093 | 0.1646 | 0.1651 |
Loa Loa (eye worm) | TK/FER protein kinase | 0.0052 | 0.0291 | 0.0292 |
Brugia malayi | conserved hypotetical protein | 0.0105 | 0.2017 | 0.2024 |
Entamoeba histolytica | protein kinase, putative | 0.009 | 0.1531 | 0.1733 |
Brugia malayi | Steroid receptor seven-up type 2 | 0.0222 | 0.5835 | 0.5855 |
Schistosoma mansoni | nuclear hormone receptor | 0.0222 | 0.5835 | 0.5855 |
Echinococcus granulosus | Nuclear hormone receptor family member nhr 41 | 0.0222 | 0.5835 | 0.571 |
Toxoplasma gondii | AGC kinase | 0.009 | 0.1531 | 0.5 |
Plasmodium falciparum | RAC-beta serine/threonine protein kinase | 0.006 | 0.0555 | 0.5 |
Loa Loa (eye worm) | TK/FER protein kinase | 0.0052 | 0.0291 | 0.0292 |
Loa Loa (eye worm) | hypothetical protein | 0.0117 | 0.2426 | 0.2434 |
Echinococcus multilocularis | tyrosine protein kinase Blk | 0.0311 | 0.872 | 0.8712 |
Schistosoma mansoni | Tr4/Tr2 (homologue) | 0.0222 | 0.5835 | 0.5855 |
Brugia malayi | Nuclear hormone receptor family member nhr-3 | 0.0222 | 0.5835 | 0.5855 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-49 | 0.0222 | 0.5835 | 0.5855 |
Schistosoma mansoni | retinoic acid receptor RXR | 0.0222 | 0.5835 | 0.5855 |
Brugia malayi | ecdysone receptor | 0.0105 | 0.2017 | 0.2024 |
Loa Loa (eye worm) | hypothetical protein | 0.0117 | 0.2426 | 0.2434 |
Schistosoma mansoni | nuclear receptor | 0.0105 | 0.2017 | 0.2024 |
Schistosoma mansoni | coup transcription factor | 0.0222 | 0.5835 | 0.5855 |
Echinococcus multilocularis | tyrosine protein kinase Fyn | 0.0349 | 0.9966 | 1 |
Loa Loa (eye worm) | variant SH3 domain-containing protein | 0.0078 | 0.1131 | 0.1135 |
Schistosoma mansoni | RAR-like nuclear receptor | 0.0222 | 0.5835 | 0.5855 |
Schistosoma mansoni | ecdysone-induced protein 78c (dr-78) | 0.0117 | 0.2426 | 0.2434 |
Loa Loa (eye worm) | hypothetical protein | 0.0105 | 0.2017 | 0.2024 |
Schistosoma mansoni | tyrosine kinase | 0.0268 | 0.7318 | 0.7343 |
Trichomonas vaginalis | AGC family protein kinase | 0.0093 | 0.1646 | 0.5 |
Brugia malayi | Tyrosine-protein kinase abl-1 | 0.011 | 0.2174 | 0.2182 |
Brugia malayi | nuclear hormone receptor | 0.0222 | 0.5835 | 0.5855 |
Echinococcus granulosus | nuclear receptor subfamily 4 group A | 0.0105 | 0.2017 | 0.1777 |
Schistosoma mansoni | tyrosine kinase | 0.019 | 0.4789 | 0.4805 |
Echinococcus granulosus | growth factor receptor bound protein 2 | 0.0078 | 0.1131 | 0.0865 |
Schistosoma mansoni | tyrosine kinase | 0.009 | 0.1537 | 0.1543 |
Brugia malayi | Nuclear hormone receptor family member nhr-14 | 0.0222 | 0.5835 | 0.5855 |
Loa Loa (eye worm) | hypothetical protein | 0.0052 | 0.0291 | 0.0292 |
Schistosoma mansoni | nuclear hormone receptor | 0.0105 | 0.2017 | 0.2024 |
Brugia malayi | Protein kinase domain containing protein | 0.0093 | 0.1646 | 0.1651 |
Brugia malayi | hypothetical protein | 0.0105 | 0.2017 | 0.2024 |
Brugia malayi | nuclear receptor NHR-88 | 0.0105 | 0.2017 | 0.2024 |
Brugia malayi | Tyrosine-protein kinase abl-1 | 0.0158 | 0.3745 | 0.3758 |
Loa Loa (eye worm) | hypothetical protein | 0.0105 | 0.2017 | 0.2024 |
Brugia malayi | Protein kinase domain containing protein | 0.0093 | 0.1635 | 0.164 |
Brugia malayi | Nuclear hormone receptor family member nhr-19 | 0.0222 | 0.5835 | 0.5855 |
Brugia malayi | Nuclear hormone receptor family member nhr-19 | 0.0222 | 0.5835 | 0.5855 |
Echinococcus multilocularis | tyrosine protein kinase HCK | 0.0271 | 0.7442 | 0.7391 |
Trichomonas vaginalis | AGC family protein kinase | 0.0093 | 0.1646 | 0.5 |
Schistosoma mansoni | nck2/grb4 | 0.0078 | 0.1131 | 0.1135 |
Schistosoma mansoni | tyrosine kinase | 0.0093 | 0.1635 | 0.164 |
Brugia malayi | Nuclear hormone receptor family member nhr-25 | 0.0222 | 0.5835 | 0.5855 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-41 | 0.0222 | 0.5835 | 0.5855 |
Echinococcus multilocularis | ecdysone induced protein 78C | 0.0222 | 0.5835 | 0.573 |
Schistosoma mansoni | FTZ-F1 nuclear receptor-like protein | 0.0222 | 0.5835 | 0.5855 |
Echinococcus multilocularis | tyrosine protein kinase Src64B | 0.0349 | 0.9966 | 1 |
Brugia malayi | nuclear receptor subfamily 1, group D, member 1, putative | 0.0105 | 0.2017 | 0.2024 |
Loa Loa (eye worm) | hypothetical protein | 0.0222 | 0.5835 | 0.5855 |
Echinococcus granulosus | nuclear receptor nhr 48 | 0.0105 | 0.2017 | 0.1777 |
Loa Loa (eye worm) | hypothetical protein | 0.0105 | 0.2017 | 0.2024 |
Loa Loa (eye worm) | hypothetical protein | 0.008 | 0.1222 | 0.1226 |
Echinococcus granulosus | Nuclear hormone receptor HR96 | 0.0105 | 0.2017 | 0.1777 |
Echinococcus multilocularis | tyrosine protein kinase Fyn | 0.0311 | 0.872 | 0.8712 |
Brugia malayi | Nuclear hormone receptor-like 1 | 0.0117 | 0.2426 | 0.2434 |
Echinococcus multilocularis | nuclear receptor 2DBD gamma | 0.0222 | 0.5835 | 0.573 |
Onchocerca volvulus | 0.0105 | 0.2017 | 0.3113 | |
Echinococcus multilocularis | nuclear receptor 2DBD gamma | 0.0105 | 0.2017 | 0.1784 |
Echinococcus granulosus | tyrosine protein kinase Btk29A | 0.009 | 0.1537 | 0.1283 |
Entamoeba histolytica | protein kinase 2, putative | 0.006 | 0.0555 | 0.0369 |
Echinococcus granulosus | c src tyrosine kinase | 0.009 | 0.1537 | 0.1283 |
Loa Loa (eye worm) | DR-78 | 0.0105 | 0.2017 | 0.2024 |
Schistosoma mansoni | nuclear receptor | 0.0105 | 0.2017 | 0.2024 |
Loa Loa (eye worm) | hypothetical protein | 0.0222 | 0.5835 | 0.5855 |
Echinococcus multilocularis | Glutaredoxin protein 5 | 0.0059 | 0.052 | 0.0237 |
Brugia malayi | Protein kinase domain containing protein | 0.0052 | 0.0291 | 0.0292 |
Loa Loa (eye worm) | TK/EGFR protein kinase | 0.0268 | 0.7318 | 0.7343 |
Schistosoma mansoni | tyrosine kinase | 0.0052 | 0.0291 | 0.0292 |
Echinococcus granulosus | serine threonine protein kinase nrc | 0.006 | 0.0555 | 0.0272 |
Loa Loa (eye worm) | hypothetical protein | 0.0222 | 0.5835 | 0.5855 |
Loa Loa (eye worm) | hypothetical protein | 0.0222 | 0.5835 | 0.5855 |
Loa Loa (eye worm) | hypothetical protein | 0.0105 | 0.2017 | 0.2024 |
Echinococcus multilocularis | c src tyrosine kinase | 0.009 | 0.1537 | 0.1288 |
Loa Loa (eye worm) | hypothetical protein | 0.0078 | 0.1131 | 0.1135 |
Loa Loa (eye worm) | hypothetical protein | 0.0105 | 0.2017 | 0.2024 |
Echinococcus granulosus | epidermal growth factor receptor | 0.0149 | 0.3453 | 0.3257 |
Schistosoma mansoni | tyrosine kinase | 0.0136 | 0.3047 | 0.3058 |
Loa Loa (eye worm) | hypothetical protein | 0.0105 | 0.2017 | 0.2024 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-14 | 0.0222 | 0.5835 | 0.5855 |
Echinococcus granulosus | tyrosine protein kinase HCK | 0.0271 | 0.7442 | 0.7365 |
Echinococcus multilocularis | sodium:potassium dependent atpase beta subunit | 0.0059 | 0.052 | 0.0237 |
Loa Loa (eye worm) | TK protein kinase | 0.0311 | 0.872 | 0.875 |
Loa Loa (eye worm) | hypothetical protein | 0.0105 | 0.2017 | 0.2024 |
Schistosoma mansoni | lipoxygenase | 0.0116 | 0.2379 | 0.2387 |
Plasmodium vivax | rac-beta serine/threonine protein kinase, putative | 0.006 | 0.0555 | 0.5 |
Echinococcus multilocularis | FTZ F1 alpha | 0.0222 | 0.5835 | 0.573 |
Loa Loa (eye worm) | nuclear Hormone Receptor family member | 0.0222 | 0.5835 | 0.5855 |
Schistosoma mansoni | serine/threonine-protein kinase | 0.0063 | 0.067 | 0.0672 |
Schistosoma mansoni | tyrosine kinase | 0.0136 | 0.3047 | 0.3058 |
Brugia malayi | hypothetical protein | 0.0052 | 0.0291 | 0.0292 |
Echinococcus multilocularis | epidermal growth factor receptor | 0.0149 | 0.3453 | 0.3269 |
Echinococcus multilocularis | insulin growth factor 1 receptor beta | 0.0093 | 0.1635 | 0.1389 |
Echinococcus multilocularis | Nuclear hormone receptor HR96 | 0.0105 | 0.2017 | 0.1784 |
Schistosoma mansoni | tyrosine kinase | 0.0093 | 0.1635 | 0.164 |
Echinococcus multilocularis | insulin receptor | 0.0093 | 0.1635 | 0.1389 |
Trypanosoma brucei | rac serine-threonine kinase, putative | 0.0093 | 0.1646 | 0.5 |
Brugia malayi | orphan nuclear receptor NR2E1 | 0.0105 | 0.2017 | 0.2024 |
Trichomonas vaginalis | AGC family protein kinase | 0.0093 | 0.1646 | 0.5 |
Echinococcus multilocularis | serine threonine protein kinase nrc serine threonine protein kinase gad | 0.006 | 0.0555 | 0.0273 |
Onchocerca volvulus | Steroid hormone receptor family member cnr14 homolog | 0.0222 | 0.5835 | 1 |
Echinococcus granulosus | Glutaredoxin protein 5 | 0.0059 | 0.052 | 0.0236 |
Onchocerca volvulus | 0.0222 | 0.5835 | 1 | |
Loa Loa (eye worm) | hypothetical protein | 0.0117 | 0.2426 | 0.2434 |
Brugia malayi | tailless protein | 0.0105 | 0.2017 | 0.2024 |
Echinococcus granulosus | 3'partial|tyrosine protein kinase Fgr | 0.0349 | 0.9966 | 0.9965 |
Echinococcus multilocularis | tyrosine protein kinase Fyn | 0.0349 | 0.9966 | 1 |
Loa Loa (eye worm) | AGC/RSK/P70 protein kinase | 0.009 | 0.1531 | 0.1536 |
Echinococcus granulosus | thyroid hormone receptor alpha | 0.0105 | 0.2017 | 0.1777 |
Echinococcus multilocularis | Nuclear hormone receptor HR96 | 0.0105 | 0.2017 | 0.1784 |
Echinococcus multilocularis | NCK adaptor protein | 0.0078 | 0.1131 | 0.0868 |
Schistosoma mansoni | thyroid hormone receptor | 0.0222 | 0.5835 | 0.5855 |
Brugia malayi | Protein kinase domain containing protein | 0.0052 | 0.0291 | 0.0292 |
Echinococcus granulosus | nervana 2 | 0.0059 | 0.052 | 0.0236 |
Trichomonas vaginalis | AGC family protein kinase | 0.0093 | 0.1646 | 0.5 |
Schistosoma mansoni | serine/threonine-protein kinase | 0.0063 | 0.067 | 0.0672 |
Echinococcus granulosus | ecdysone induced protein 78C | 0.0222 | 0.5835 | 0.571 |
Brugia malayi | Furin-like cysteine rich region family protein | 0.0268 | 0.7318 | 0.7343 |
Schistosoma mansoni | tyrosine kinase | 0.0149 | 0.3453 | 0.3465 |
Entamoeba histolytica | PH domain containing protein kinase, putative | 0.0063 | 0.067 | 0.0529 |
Loa Loa (eye worm) | hypothetical protein | 0.0105 | 0.2017 | 0.2024 |
Echinococcus granulosus | nuclear receptor subfamily 1 group D | 0.0117 | 0.2426 | 0.2198 |
Schistosoma mansoni | tyrosine kinase | 0.0052 | 0.0291 | 0.0292 |
Echinococcus multilocularis | arachidonate 5 lipoxygenase | 0.0116 | 0.2379 | 0.2158 |
Loa Loa (eye worm) | TK protein kinase | 0.0271 | 0.7442 | 0.7468 |
Schistosoma mansoni | nuclear hormone receptor | 0.0105 | 0.2017 | 0.2024 |
Loa Loa (eye worm) | hypothetical protein | 0.0117 | 0.2426 | 0.2434 |
Echinococcus multilocularis | nuclear receptor subfamily 4 group A | 0.0105 | 0.2017 | 0.1784 |
Brugia malayi | ecdysteroid receptor | 0.0222 | 0.5835 | 0.5855 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-31 | 0.0222 | 0.5835 | 0.5855 |
Brugia malayi | SH2 domain containing protein | 0.0052 | 0.0291 | 0.0292 |
Brugia malayi | steroid hormone receptor | 0.0222 | 0.5835 | 0.5855 |
Echinococcus granulosus | Nuclear hormone receptor HR96 | 0.0105 | 0.2017 | 0.1777 |
Brugia malayi | nuclear receptor RXR | 0.0105 | 0.2017 | 0.2024 |
Echinococcus granulosus | tyrosine protein kinase Fyn | 0.0349 | 0.9966 | 0.9965 |
Brugia malayi | nuclear hormone receptor | 0.0105 | 0.2017 | 0.2024 |
Schistosoma mansoni | retinoid-x-receptor (RXR) | 0.0117 | 0.2426 | 0.2434 |
Trichomonas vaginalis | AGC family protein kinase | 0.0093 | 0.1646 | 0.5 |
Echinococcus multilocularis | hepatocyte nuclear factor 4 alpha | 0.0222 | 0.5835 | 0.573 |
Brugia malayi | nuclear receptor NHR-67 | 0.0105 | 0.2017 | 0.2024 |
Echinococcus multilocularis | nuclear receptor 2DBD gamma | 0.0222 | 0.5835 | 0.573 |
Echinococcus granulosus | hepatocyte nuclear factor 4 alpha | 0.0222 | 0.5835 | 0.571 |
Brugia malayi | Ligand-binding domain of nuclear hormone receptor family protein | 0.0222 | 0.5835 | 0.5855 |
Schistosoma mansoni | thyroid hormone receptor | 0.0222 | 0.5835 | 0.5855 |
Echinococcus multilocularis | nervana 2 | 0.0059 | 0.052 | 0.0237 |
Trypanosoma cruzi | Protein kinase B | 0.0063 | 0.067 | 1 |
Loa Loa (eye worm) | TK/FER protein kinase | 0.0052 | 0.0291 | 0.0292 |
Schistosoma mansoni | tyrosine kinase | 0.0349 | 0.9966 | 1 |
Echinococcus granulosus | sodium:potassium dependent atpase beta subunit | 0.0059 | 0.052 | 0.0236 |
Loa Loa (eye worm) | hypothetical protein | 0.0105 | 0.2017 | 0.2024 |
Schistosoma mansoni | tyrosine kinase | 0.0349 | 0.9966 | 1 |
Echinococcus multilocularis | FTZ F1 nuclear receptor protein | 0.0222 | 0.5835 | 0.573 |
Echinococcus granulosus | nervana 2 | 0.0059 | 0.052 | 0.0236 |
Echinococcus multilocularis | retinoic acid receptor rxr beta a retinoic acid receptor rxr alpha a retinoic acid receptor rxr alpha | 0.0105 | 0.2017 | 0.1784 |
Schistosoma mansoni | retinoid-x-receptor (RXR) | 0.0222 | 0.5835 | 0.5855 |
Brugia malayi | photoreceptor-specific nuclear receptor | 0.0222 | 0.5835 | 0.5855 |
Loa Loa (eye worm) | TK/FER protein kinase | 0.0052 | 0.0291 | 0.0292 |
Onchocerca volvulus | Protein ultraspiracle homolog | 0.0222 | 0.5835 | 1 |
Brugia malayi | Nuclear hormone receptor family member nhr-25 | 0.0222 | 0.5835 | 0.5855 |
Brugia malayi | Nuclear hormone receptor family member nhr-1 | 0.0222 | 0.5835 | 0.5855 |
Loa Loa (eye worm) | TK/FER protein kinase | 0.0052 | 0.0291 | 0.0292 |
Trichomonas vaginalis | AGC family protein kinase | 0.0093 | 0.1646 | 0.5 |
Brugia malayi | Protein kinase domain containing protein | 0.0052 | 0.0291 | 0.0292 |
Brugia malayi | Protein kinase domain containing protein | 0.0052 | 0.0291 | 0.0292 |
Echinococcus multilocularis | epidermal growth factor receptor | 0.0268 | 0.7318 | 0.7263 |
Onchocerca volvulus | 0.0105 | 0.2017 | 0.3113 | |
Schistosoma mansoni | zinc finger protein | 0.0105 | 0.2017 | 0.2024 |
Echinococcus granulosus | tyrosine protein kinase Src64B | 0.0349 | 0.9966 | 0.9965 |
Loa Loa (eye worm) | nuclear hormone receptor-like 1 | 0.0117 | 0.2426 | 0.2434 |
Loa Loa (eye worm) | hypothetical protein | 0.0105 | 0.2017 | 0.2024 |
Loa Loa (eye worm) | hypothetical protein | 0.0222 | 0.5835 | 0.5855 |
Loa Loa (eye worm) | TK/FER protein kinase | 0.0052 | 0.0291 | 0.0292 |
Echinococcus multilocularis | nuclear receptor nhr 48 | 0.0105 | 0.2017 | 0.1784 |
Brugia malayi | nuclear receptor NHR-88 | 0.0222 | 0.5835 | 0.5855 |
Brugia malayi | SH2 domain containing protein | 0.0052 | 0.0291 | 0.0292 |
Brugia malayi | nuclear receptor RXR | 0.0117 | 0.2426 | 0.2434 |
Brugia malayi | Nuclear hormone receptor-like 1 | 0.0117 | 0.2426 | 0.2434 |
Schistosoma mansoni | proto-oncogene tyrosine-protein kinase abl1 | 0.0078 | 0.1131 | 0.1135 |
Schistosoma mansoni | steroid hormone receptor ad4bp | 0.0222 | 0.5835 | 0.5855 |
Schistosoma mansoni | proto-oncogene tyrosine-protein kinase src | 0.009 | 0.1537 | 0.1543 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-40 | 0.0222 | 0.5835 | 0.5855 |
Loa Loa (eye worm) | TK/FER protein kinase | 0.0052 | 0.0291 | 0.0292 |
Echinococcus granulosus | arachidonate 5 lipoxygenase | 0.0116 | 0.2379 | 0.215 |
Echinococcus granulosus | NCK adaptor protein | 0.0078 | 0.1131 | 0.0865 |
Echinococcus granulosus | tyrosine protein kinase Src42A | 0.0298 | 0.8313 | 0.8263 |
Echinococcus multilocularis | tyrosine protein kinase Abl | 0.0158 | 0.3745 | 0.357 |
Echinococcus granulosus | nuclear receptor 2DBD gamma | 0.0222 | 0.5835 | 0.571 |
Echinococcus multilocularis | growth factor receptor bound protein 2 | 0.0078 | 0.1131 | 0.0868 |
Schistosoma mansoni | nuclear receptor 2DBD-gamma | 0.0222 | 0.5835 | 0.5855 |
Echinococcus multilocularis | thyroid hormone receptor alpha | 0.0222 | 0.5835 | 0.573 |
Brugia malayi | Nuclear hormone receptor E75 | 0.0105 | 0.2017 | 0.2024 |
Loa Loa (eye worm) | hypothetical protein | 0.0222 | 0.5835 | 0.5855 |
Loa Loa (eye worm) | TK/FER protein kinase | 0.0052 | 0.0291 | 0.0292 |
Brugia malayi | Sex muscle abnormal protein 5 | 0.0078 | 0.1131 | 0.1135 |
Loa Loa (eye worm) | TK/ABL protein kinase | 0.0229 | 0.6066 | 0.6087 |
Echinococcus granulosus | COUP TF:Svp nuclear hormone receptor | 0.0222 | 0.5835 | 0.571 |
Loa Loa (eye worm) | hypothetical protein | 0.0105 | 0.2017 | 0.2024 |
Loa Loa (eye worm) | nuclear receptor nhr-7B | 0.0105 | 0.2017 | 0.2024 |
Echinococcus granulosus | tyrosine protein kinase ABL1 | 0.0229 | 0.6066 | 0.5949 |
Entamoeba histolytica | protein kinase, putative | 0.0093 | 0.1646 | 0.1894 |
Trichomonas vaginalis | AGC family protein kinase | 0.0093 | 0.1646 | 0.5 |
Schistosoma mansoni | adapter molecule crk | 0.0078 | 0.1131 | 0.1135 |
Echinococcus multilocularis | tyrosine protein kinase Fyn | 0.0349 | 0.9966 | 1 |
Loa Loa (eye worm) | TK/FER protein kinase | 0.0052 | 0.0291 | 0.0292 |
Echinococcus granulosus | insulin receptor | 0.0093 | 0.1635 | 0.1384 |
Echinococcus granulosus | tyrosine protein kinase Src42A | 0.0349 | 0.9966 | 0.9965 |
Schistosoma mansoni | nuclear hormone receptor nor-1/nor-2 | 0.0222 | 0.5835 | 0.5855 |
Echinococcus granulosus | melanoma receptor tyrosine protein kinase | 0.0149 | 0.3453 | 0.3257 |
Echinococcus multilocularis | tyrosine protein kinase ABL1 | 0.0229 | 0.6066 | 0.597 |
Brugia malayi | p70 ribosomal S6 kinase beta | 0.009 | 0.1531 | 0.1536 |
Schistosoma mansoni | tyrosine kinase | 0.0136 | 0.3047 | 0.3058 |
Echinococcus granulosus | FTZ F1 alpha | 0.0222 | 0.5835 | 0.571 |
Loa Loa (eye worm) | SRC-1 | 0.0349 | 0.9966 | 1 |
Echinococcus granulosus | tyrosine protein kinase Fyn | 0.0349 | 0.9966 | 0.9965 |
Schistosoma mansoni | serine/threonine protein kinase | 0.0051 | 0.0259 | 0.026 |
Echinococcus multilocularis | tyrosine protein kinase Src42A | 0.0349 | 0.9966 | 1 |
Loa Loa (eye worm) | TK/FER protein kinase | 0.0052 | 0.0291 | 0.0292 |
Echinococcus multilocularis | proto oncogene tyrosine protein kinase LCK | 0.0349 | 0.9966 | 1 |
Brugia malayi | Nuclear hormone receptor family member nhr-40 | 0.0222 | 0.5835 | 0.5855 |
Brugia malayi | protein-tyrosine kinase | 0.0311 | 0.872 | 0.875 |
Brugia malayi | SRC-1 | 0.0349 | 0.9966 | 1 |
Brugia malayi | Nuclear hormone receptor family member nhr-49 | 0.0222 | 0.5835 | 0.5855 |
Brugia malayi | Variant SH3 domain containing protein | 0.0078 | 0.1131 | 0.1135 |
Brugia malayi | Variant SH3 domain containing protein | 0.0078 | 0.1131 | 0.1135 |
Loa Loa (eye worm) | sex muscle abnormal protein 5 | 0.0078 | 0.1131 | 0.1135 |
Echinococcus granulosus | tyrosine protein kinase Blk | 0.0311 | 0.872 | 0.8681 |
Echinococcus granulosus | epidermal growth factor receptor | 0.0268 | 0.7318 | 0.7237 |
Echinococcus multilocularis | nervana 2 | 0.0059 | 0.052 | 0.0237 |
Echinococcus multilocularis | tyrosine protein kinase Btk29A | 0.009 | 0.1537 | 0.1288 |
Echinococcus granulosus | nuclear receptor 2DBD gamma | 0.0222 | 0.5835 | 0.571 |
Echinococcus multilocularis | tyrosine protein kinase Src42A | 0.0298 | 0.8313 | 0.8292 |
Echinococcus multilocularis | tyrosine protein kinase Srms | 0.0311 | 0.872 | 0.8712 |
Loa Loa (eye worm) | hypothetical protein | 0.0105 | 0.2017 | 0.2024 |
Echinococcus multilocularis | nuclear receptor subfamily 1 group D | 0.0117 | 0.2426 | 0.2206 |
Brugia malayi | Ligand-binding domain of nuclear hormone receptor family protein | 0.0222 | 0.5835 | 0.5855 |
Echinococcus granulosus | insulin growth factor 1 receptor beta | 0.0093 | 0.1635 | 0.1384 |
Echinococcus granulosus | serine/threonine protein kinase | 0.0063 | 0.067 | 0.039 |
Echinococcus multilocularis | COUP TF:Svp nuclear hormone receptor | 0.0222 | 0.5835 | 0.573 |
Onchocerca volvulus | Nuclear receptor subfamily 6 group A member 1 homolog | 0.0105 | 0.2017 | 0.3113 |
Schistosoma mansoni | photoreceptor-specific nuclear receptor related | 0.0222 | 0.5835 | 0.5855 |
Schistosoma mansoni | growth factor receptor-bound protein | 0.0078 | 0.1131 | 0.1135 |
Brugia malayi | Nuclear hormone receptor family member nhr-31 | 0.0222 | 0.5835 | 0.5855 |
Echinococcus granulosus | proto oncogene tyrosine protein kinase LCK | 0.0349 | 0.9966 | 0.9965 |
Loa Loa (eye worm) | hypothetical protein | 0.0117 | 0.2426 | 0.2434 |
Echinococcus granulosus | nuclear receptor 2DBD gamma | 0.0105 | 0.2017 | 0.1777 |
Echinococcus multilocularis | tyrosine protein kinase lyn lyn a protein tyrosine kinase lymphocyte specific protein tyrosine kinase | 0.0349 | 0.9966 | 1 |
Trypanosoma cruzi | rac serine-threonine kinase, putative | 0.0063 | 0.067 | 1 |
Echinococcus multilocularis | tyrosine protein kinase lyn tyrosine protein kinase blk | 0.0349 | 0.9966 | 1 |
Schistosoma mansoni | hepatocyte nuclear factor 4-alpha (hnf-4-alpha) | 0.0105 | 0.2017 | 0.2024 |
Brugia malayi | nuclear hormone receptor family member odr-7 | 0.0105 | 0.2017 | 0.2024 |
Giardia lamblia | Kinase, AGC PKA | 0.006 | 0.0555 | 0.5 |
Brugia malayi | Nuclear hormone receptor-like 1 | 0.0222 | 0.5835 | 0.5855 |
Echinococcus granulosus | retinoic acid receptor rxr beta a | 0.0222 | 0.5835 | 0.571 |
Echinococcus multilocularis | Nuclear hormone receptor family member nhr 41 | 0.0222 | 0.5835 | 0.573 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-1 | 0.0222 | 0.5835 | 0.5855 |
Entamoeba histolytica | PH domain containing protein kinase, putative | 0.0063 | 0.067 | 0.0529 |
Echinococcus granulosus | tyrosine protein kinase Fyn | 0.0349 | 0.9966 | 0.9965 |
Echinococcus granulosus | calcium:calmodulin dependent protein kinase | 0.006 | 0.0555 | 0.0272 |
Loa Loa (eye worm) | hypothetical protein | 0.0105 | 0.2017 | 0.2024 |
Brugia malayi | nuclear hormone receptor family member nhr-6 | 0.0105 | 0.2017 | 0.2024 |
Activity type | Activity value | Assay description | Source | Reference |
---|---|---|---|---|
ID50 (functional) | = 260 ng ml-1 | compound was evaluated in vitro for growth inhibition of B16 (Murinemelanoma cell line) cell | ChEMBL. | 3476754 |
ID50 (functional) | = 600 ng ml-1 | Compound was evaluated in vitro for growth inhibition of CCRF-CEM (Human leukemic lymphoblastic) cell | ChEMBL. | 3476754 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.
1 literature reference was collected for this gene.