Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Entamoeba histolytica | deoxyuridine 5-triphosphate nucleotidohydrolase domain containing protein | 0.0069 | 0.0239 | 0.0182 |
Brugia malayi | latrophilin 2 splice variant baaae | 0.0074 | 0.0268 | 0.1527 |
Trypanosoma brucei | cytidine deaminase | 0.0053 | 0.0149 | 0.0149 |
Loa Loa (eye worm) | pigment dispersing factor receptor c | 0.0109 | 0.0459 | 0.2763 |
Plasmodium vivax | thymidylate kinase, putative | 0.0154 | 0.0711 | 1 |
Schistosoma mansoni | hypothetical protein | 0.0037 | 0.0063 | 0.0046 |
Echinococcus multilocularis | guanine nucleotide binding protein G(s) subunit | 0.0052 | 0.0146 | 0.014 |
Trypanosoma brucei | RNA helicase, putative | 0.0501 | 0.2641 | 0.2721 |
Onchocerca volvulus | 0.005 | 0.0134 | 0.0709 | |
Giardia lamblia | Ribonuclease H | 0.0092 | 0.0365 | 0.0305 |
Trypanosoma brucei | ingi protein (ORF1) | 0.0103 | 0.0428 | 0.0437 |
Brugia malayi | Latrophilin receptor protein 2 | 0.0034 | 0.0047 | 0.018 |
Brugia malayi | exodeoxyribonuclease III family protein | 0.006 | 0.019 | 0.105 |
Onchocerca volvulus | 0.0053 | 0.0149 | 0.0802 | |
Trypanosoma brucei | DNA polymerase kappa, putative | 0.0039 | 0.0071 | 0.0069 |
Trypanosoma cruzi | UMP-CMP kinase, mitochondrial, putative | 0.006 | 0.0192 | 0.0133 |
Entamoeba histolytica | exodeoxyribonuclease III, putative | 0.006 | 0.019 | 0.0131 |
Loa Loa (eye worm) | hypothetical protein | 0.0037 | 0.0063 | 0.038 |
Brugia malayi | Deoxynucleoside kinase family protein | 0.0069 | 0.0239 | 0.1347 |
Loa Loa (eye worm) | hypothetical protein | 0.0037 | 0.0063 | 0.038 |
Plasmodium vivax | AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative | 0.006 | 0.019 | 0.2487 |
Echinococcus multilocularis | GPCR, family 2 | 0.0034 | 0.0047 | 0.0041 |
Schistosoma mansoni | ap endonuclease | 0.006 | 0.019 | 0.0173 |
Loa Loa (eye worm) | latrophilin receptor protein 2 | 0.0034 | 0.0047 | 0.028 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0062 | 0.02 | 0.0202 |
Echinococcus granulosus | histone lysine methyltransferase setb | 0.0029 | 0.0017 | 0.0011 |
Trypanosoma cruzi | myo-inositol-1(or 4)-monophosphatase 1, putative | 0.0116 | 0.0499 | 0.0452 |
Trichomonas vaginalis | ribonuclease H1, putative | 0.0092 | 0.0365 | 0.0313 |
Plasmodium falciparum | AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative | 0.006 | 0.019 | 0.057 |
Onchocerca volvulus | 0.0053 | 0.0149 | 0.0802 | |
Toxoplasma gondii | inositol(myo)-1(or 4)-monophosphatase 2, putative | 0.0116 | 0.0499 | 0.6935 |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.0052 | 0.0146 | 0.0129 |
Brugia malayi | Hypothetical 52.5 kDa protein ZK945.1 in chromosome II, putative | 0.0037 | 0.0063 | 0.0281 |
Onchocerca volvulus | 0.0056 | 0.0167 | 0.0909 | |
Echinococcus granulosus | diuretic hormone 44 receptor GPRdih2 | 0.0034 | 0.0047 | 0.0041 |
Echinococcus granulosus | thymidine kinase | 0.1824 | 1 | 1 |
Echinococcus multilocularis | thymidine kinase | 0.1824 | 1 | 1 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0062 | 0.02 | 0.0202 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0069 | 0.0239 | 0.0182 |
Brugia malayi | hypothetical protein | 0.0035 | 0.0051 | 0.0206 |
Echinococcus granulosus | Basic leucine zipper bZIP transcription | 0.0037 | 0.0063 | 0.0057 |
Trichomonas vaginalis | ap endonuclease, putative | 0.006 | 0.019 | 0.0131 |
Mycobacterium tuberculosis | Probable cytidine deaminase Cdd (cytidine aminohydrolase) (cytidine nucleoside deaminase) | 0.0053 | 0.0149 | 0.0766 |
Loa Loa (eye worm) | hypothetical protein | 0.0039 | 0.0071 | 0.0428 |
Treponema pallidum | thymidylate kinase (tmk) | 0.0154 | 0.0711 | 1 |
Trypanosoma brucei | DNA polymerase IV, putative | 0.0039 | 0.0071 | 0.0069 |
Giardia lamblia | CDC8 | 0.0154 | 0.0711 | 0.0665 |
Schistosoma mansoni | lamin | 0.0056 | 0.0167 | 0.015 |
Echinococcus multilocularis | guanine nucleotide binding protein G(s) subunit | 0.0052 | 0.0146 | 0.014 |
Loa Loa (eye worm) | cytoplasmic intermediate filament protein | 0.003 | 0.0022 | 0.0134 |
Echinococcus multilocularis | thymidylate kinase | 0.0154 | 0.0711 | 0.0706 |
Schistosoma mansoni | aldehyde dehydrogenase | 0.0062 | 0.0201 | 0.0184 |
Echinococcus multilocularis | thyroid hormone receptor alpha | 0.016 | 0.0744 | 0.0739 |
Echinococcus multilocularis | geminin | 0.0512 | 0.2704 | 0.27 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0062 | 0.02 | 0.0202 |
Trichomonas vaginalis | thymidylate kinase, putative | 0.0154 | 0.0711 | 0.0673 |
Echinococcus granulosus | concentrative Na nucleoside cotransporter | 0.0338 | 0.1734 | 0.1729 |
Entamoeba histolytica | deoxyuridine 5-triphosphate nucleotidohydrolase domain containing protein | 0.0069 | 0.0239 | 0.0182 |
Loa Loa (eye worm) | hypothetical protein | 0.0056 | 0.0167 | 0.1002 |
Toxoplasma gondii | ABC1 family protein | 0.0037 | 0.0063 | 0.0666 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0062 | 0.02 | 0.0202 |
Entamoeba histolytica | hypothetical protein | 0.0069 | 0.0239 | 0.0182 |
Echinococcus granulosus | lamin dm0 | 0.0056 | 0.0167 | 0.0161 |
Leishmania major | ribonuclease H1, putative | 0.0092 | 0.0365 | 0.0313 |
Entamoeba histolytica | glycogen phosphorylase, putative | 0.014 | 0.0637 | 0.0596 |
Entamoeba histolytica | hypothetical protein | 0.0069 | 0.0239 | 0.0182 |
Leishmania major | cathepsin L-like protease | 0.0062 | 0.02 | 0.0142 |
Echinococcus multilocularis | NADH ubiquinone oxidoreductase 42 kDa subunit | 0.0069 | 0.0239 | 0.0233 |
Echinococcus multilocularis | histone lysine N methyltransferase SETMAR | 0.0029 | 0.0017 | 0.0011 |
Loa Loa (eye worm) | hypothetical protein | 0.0245 | 0.1219 | 0.7332 |
Leishmania major | cytidine deaminase-like protein | 0.0053 | 0.0149 | 0.0089 |
Loa Loa (eye worm) | intermediate filament protein | 0.0056 | 0.0167 | 0.1002 |
Brugia malayi | GTP-binding regulatory protein Gs alpha-S chain, putative | 0.0052 | 0.0146 | 0.0783 |
Trypanosoma brucei | DNA polymerase kappa, putative | 0.0039 | 0.0071 | 0.0069 |
Echinococcus multilocularis | sodium:nucleoside cotransporter 2 | 0.022 | 0.108 | 0.1075 |
Entamoeba histolytica | hypothetical protein | 0.0069 | 0.0239 | 0.0182 |
Schistosoma mansoni | terminal deoxycytidyl transferase | 0.0039 | 0.0071 | 0.0054 |
Entamoeba histolytica | glycogen phosphorylase, putative | 0.0325 | 0.1662 | 0.166 |
Schistosoma mansoni | hypothetical protein | 0.005 | 0.0134 | 0.0117 |
Loa Loa (eye worm) | pre-SET domain-containing protein family protein | 0.0202 | 0.0981 | 0.5898 |
Entamoeba histolytica | cytidine deaminase, putative | 0.0053 | 0.0149 | 0.0089 |
Echinococcus granulosus | 5'partial|histone lysine N methyltransferase SETDB2 | 0.0028 | 0.0011 | 0.0005 |
Trypanosoma brucei | hypothetical protein, conserved | 0.0103 | 0.0428 | 0.0437 |
Trypanosoma brucei | ribonuclease H1 | 0.0092 | 0.0365 | 0.0372 |
Echinococcus multilocularis | lamin dm0 | 0.0056 | 0.0167 | 0.0161 |
Toxoplasma gondii | LsmAD domain-containing protein | 0.0054 | 0.0158 | 0.2033 |
Giardia lamblia | Hypothetical protein | 0.0069 | 0.0239 | 0.0174 |
Plasmodium falciparum | thymidylate kinase | 0.0154 | 0.0711 | 1 |
Giardia lamblia | Glycogen phosphorylase | 0.0325 | 0.1662 | 0.1653 |
Entamoeba histolytica | hypothetical protein | 0.0069 | 0.0239 | 0.0182 |
Leishmania major | thymidylate kinase-like protein | 0.0154 | 0.0711 | 0.0673 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0062 | 0.02 | 0.0202 |
Trypanosoma brucei | thymidylate kinase, putative | 0.0154 | 0.0711 | 0.073 |
Plasmodium vivax | ataxin-2 like protein, putative | 0.0054 | 0.0158 | 0.2033 |
Echinococcus multilocularis | survival motor neuron protein 1 | 0.0245 | 0.1219 | 0.1214 |
Brugia malayi | RNase H family protein | 0.0092 | 0.0365 | 0.2115 |
Giardia lamblia | Deoxyguanosine kinase/deoxyadenosine kinase subunit, putative | 0.0069 | 0.0239 | 0.0174 |
Brugia malayi | carbohydrate phosphorylase | 0.0325 | 0.1662 | 1 |
Schistosoma mansoni | phosphoglucomutase | 0.0092 | 0.0365 | 0.0349 |
Mycobacterium tuberculosis | Thymidylate kinase Tmk (dTMP kinase) (thymidylic acid kinase) (TMPK) | 0.0154 | 0.0711 | 0.5795 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0062 | 0.02 | 0.0202 |
Echinococcus multilocularis | transfer RNA-Ile | 0.1824 | 1 | 1 |
Giardia lamblia | Hypothetical protein | 0.0069 | 0.0239 | 0.0174 |
Trypanosoma cruzi | apurinic/apyrimidinic endonuclease | 0.006 | 0.019 | 0.0131 |
Trichomonas vaginalis | inositol monophosphatase, putative | 0.0116 | 0.0499 | 0.0452 |
Trypanosoma brucei | PAB1-binding protein , putative | 0.0054 | 0.0158 | 0.0159 |
Brugia malayi | Corticotropin releasing factor receptor 2 precursor, putative | 0.0109 | 0.0459 | 0.2688 |
Trichomonas vaginalis | DNA polymerase IV / kappa, putative | 0.0039 | 0.0071 | 0.0008 |
Echinococcus multilocularis | arachidonate 5 lipoxygenase | 0.0057 | 0.0174 | 0.0168 |
Wolbachia endosymbiont of Brugia malayi | fructose-1,6-bisphosphatase | 0.0116 | 0.0499 | 0.592 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0062 | 0.02 | 0.0202 |
Giardia lamblia | Endonuclease/Exonuclease/phosphatase | 0.006 | 0.019 | 0.0123 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0062 | 0.02 | 0.0202 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0062 | 0.02 | 0.0202 |
Brugia malayi | ImpB/MucB/SamB family protein | 0.0039 | 0.0071 | 0.033 |
Leishmania major | cathepsin L-like protease | 0.0062 | 0.02 | 0.0142 |
Brugia malayi | beta-lactamase family protein | 0.0037 | 0.0063 | 0.0281 |
Schistosoma mansoni | NADH-ubiquinone oxidoreductase | 0.0069 | 0.0239 | 0.0222 |
Mycobacterium leprae | possible inositol monophosphatase SubH (IMPase) (inositol-1-phosphatase) (I-1-Pase ). | 0.0103 | 0.0431 | 0.5677 |
Trypanosoma cruzi | UMP-CMP kinase, mitochondrial, putative | 0.006 | 0.0192 | 0.0133 |
Trypanosoma brucei | DNA polymerase kappa, putative | 0.0039 | 0.0071 | 0.0069 |
Echinococcus granulosus | dna polymerase kappa | 0.0039 | 0.0071 | 0.0066 |
Loa Loa (eye worm) | exodeoxyribonuclease III family protein | 0.006 | 0.019 | 0.1141 |
Mycobacterium ulcerans | glycogen phosphorylase GlgP | 0.014 | 0.0637 | 0.8849 |
Brugia malayi | Calcitonin receptor-like protein seb-1 | 0.0109 | 0.0459 | 0.2688 |
Trichomonas vaginalis | glycogen phosphorylase, putative | 0.0325 | 0.1662 | 0.166 |
Trypanosoma brucei | DNA polymerase eta, putative | 0.0039 | 0.0071 | 0.0069 |
Mycobacterium tuberculosis | Conserved hypothetical protein | 0.0039 | 0.0071 | 0.0071 |
Loa Loa (eye worm) | hypothetical protein | 0.0027 | 0.0006 | 0.0034 |
Brugia malayi | Pre-SET motif family protein | 0.0202 | 0.0981 | 0.5856 |
Mycobacterium ulcerans | cytidine deaminase | 0.0053 | 0.0149 | 0.1322 |
Echinococcus multilocularis | DNA (apurinic or apyrimidinic site) lyase | 0.006 | 0.019 | 0.0184 |
Leishmania major | DNA polymerase eta, putative | 0.0039 | 0.0071 | 0.0008 |
Loa Loa (eye worm) | inositol-1 | 0.0116 | 0.0499 | 0.2999 |
Onchocerca volvulus | 0.0056 | 0.0167 | 0.0909 | |
Echinococcus multilocularis | concentrative Na+ nucleoside cotransporter | 0.0338 | 0.1734 | 0.1729 |
Trypanosoma brucei | inositol-1(or 4)-monophosphatase 1, putative | 0.0116 | 0.0499 | 0.051 |
Leishmania major | hypothetical protein, conserved | 0.006 | 0.0192 | 0.0133 |
Schistosoma mansoni | thyroid hormone receptor | 0.016 | 0.0744 | 0.0729 |
Schistosoma mansoni | family S12 unassigned peptidase (S12 family) | 0.0037 | 0.0063 | 0.0046 |
Onchocerca volvulus | 0.023 | 0.1136 | 0.68 | |
Mycobacterium tuberculosis | Probable glycogen phosphorylase GlgP | 0.014 | 0.0637 | 0.5128 |
Mycobacterium tuberculosis | Probable aldehyde dehydrogenase | 0.0062 | 0.0201 | 0.1232 |
Wolbachia endosymbiont of Brugia malayi | ribonuclease HI | 0.0092 | 0.0365 | 0.3359 |
Brugia malayi | RNase H family protein | 0.0092 | 0.0365 | 0.2115 |
Trypanosoma brucei | unspecified product | 0.0103 | 0.0428 | 0.0437 |
Schistosoma mansoni | thyroid hormone receptor | 0.016 | 0.0744 | 0.0729 |
Entamoeba histolytica | thymidine kinase, putative | 0.1769 | 0.9697 | 1 |
Mycobacterium ulcerans | aldehyde dehydrogenase | 0.0062 | 0.0201 | 0.2125 |
Echinococcus multilocularis | cadherin EGF LAG seven pass G type receptor | 0.0034 | 0.0047 | 0.0041 |
Mycobacterium ulcerans | DNA polymerase IV | 0.0039 | 0.0071 | 0.0123 |
Trypanosoma cruzi | PAB1-binding protein , putative | 0.0054 | 0.0158 | 0.0099 |
Schistosoma mansoni | ap endonuclease | 0.006 | 0.019 | 0.0173 |
Echinococcus multilocularis | lamin | 0.0056 | 0.0167 | 0.0161 |
Brugia malayi | intermediate filament protein | 0.0056 | 0.0167 | 0.0909 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0069 | 0.0239 | 0.0182 |
Trichomonas vaginalis | glycogen phosphorylase, putative | 0.0325 | 0.1662 | 0.166 |
Entamoeba histolytica | hypothetical protein | 0.0069 | 0.0239 | 0.0182 |
Mycobacterium tuberculosis | Possible penicillin-binding protein | 0.0238 | 0.1182 | 1 |
Echinococcus multilocularis | cytidine deaminase | 0.0053 | 0.0149 | 0.0143 |
Trypanosoma brucei | DNA polymerase kappa, putative | 0.0039 | 0.0071 | 0.0069 |
Entamoeba histolytica | hypothetical protein | 0.0069 | 0.0239 | 0.0182 |
Schistosoma mansoni | hypothetical protein | 0.0501 | 0.2641 | 0.2629 |
Trypanosoma cruzi | DNA polymerase eta, putative | 0.0039 | 0.0071 | 0.0008 |
Schistosoma mansoni | lipoxygenase | 0.0057 | 0.0174 | 0.0157 |
Loa Loa (eye worm) | hypothetical protein | 0.0029 | 0.0017 | 0.0102 |
Onchocerca volvulus | 0.0037 | 0.0063 | 0.0281 | |
Leishmania major | apurinic/apyrimidinic endonuclease-redox protein | 0.006 | 0.019 | 0.0131 |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.0052 | 0.0146 | 0.0129 |
Toxoplasma gondii | aldehyde dehydrogenase | 0.0062 | 0.0201 | 0.265 |
Echinococcus granulosus | GPCR family 2 | 0.0034 | 0.0047 | 0.0041 |
Echinococcus granulosus | dna polymerase eta | 0.0039 | 0.0071 | 0.0066 |
Loa Loa (eye worm) | hypothetical protein | 0.0037 | 0.0063 | 0.038 |
Trypanosoma cruzi | myo-inositol-1(or 4)-monophosphatase 1, putative | 0.0116 | 0.0499 | 0.0452 |
Schistosoma mansoni | inositol monophosphatase | 0.0116 | 0.0499 | 0.0482 |
Schistosoma mansoni | thymidylate kinase | 0.0154 | 0.0711 | 0.0696 |
Schistosoma mansoni | lamin | 0.0056 | 0.0167 | 0.015 |
Leishmania major | cathepsin L-like protease | 0.0062 | 0.02 | 0.0142 |
Trichomonas vaginalis | cytidine deaminase, putative | 0.0053 | 0.0149 | 0.0089 |
Mycobacterium ulcerans | DNA polymerase IV | 0.0039 | 0.0071 | 0.0123 |
Toxoplasma gondii | ribonuclease HI protein | 0.0092 | 0.0365 | 0.5011 |
Entamoeba histolytica | deoxycytidyl transferase, putative | 0.0039 | 0.0071 | 0.0008 |
Echinococcus multilocularis | solute carrier family 28 | 0.0338 | 0.1734 | 0.1729 |
Trypanosoma cruzi | cysteine peptidase, clan CA, family C1, cathepsin L-like, putative | 0.0057 | 0.0171 | 0.0111 |
Onchocerca volvulus | 0.0037 | 0.0063 | 0.0281 | |
Trypanosoma brucei | DNA polymerase kappa, putative | 0.0039 | 0.0071 | 0.0069 |
Schistosoma mansoni | glycogen phosphorylase | 0.0325 | 0.1662 | 0.1648 |
Echinococcus multilocularis | inositol monophosphatase 1 | 0.0116 | 0.0499 | 0.0493 |
Echinococcus granulosus | lamin | 0.0056 | 0.0167 | 0.0161 |
Schistosoma mansoni | hypothetical protein | 0.0034 | 0.0047 | 0.003 |
Echinococcus multilocularis | diuretic hormone 44 receptor GPRdih2 | 0.0034 | 0.0047 | 0.0041 |
Echinococcus granulosus | geminin | 0.0512 | 0.2704 | 0.27 |
Loa Loa (eye worm) | glycogen phosphorylase | 0.0325 | 0.1662 | 1 |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.0052 | 0.0146 | 0.0129 |
Brugia malayi | beta-lactamase | 0.0037 | 0.0063 | 0.0281 |
Trypanosoma brucei | hypothetical protein, conserved | 0.0037 | 0.0063 | 0.0061 |
Leishmania major | hypothetical protein, conserved | 0.0054 | 0.0158 | 0.0099 |
Chlamydia trachomatis | glycogen phosphorylase | 0.0325 | 0.1662 | 1 |
Entamoeba histolytica | hypothetical protein | 0.0069 | 0.0239 | 0.0182 |
Echinococcus granulosus | solute carrier family 28 | 0.0338 | 0.1734 | 0.1729 |
Trypanosoma cruzi | ribonuclease H1, putative | 0.0092 | 0.0365 | 0.0313 |
Echinococcus multilocularis | musashi | 0.0056 | 0.0167 | 0.0161 |
Brugia malayi | thymidylate kinase | 0.0154 | 0.0711 | 0.4221 |
Toxoplasma gondii | cytidine and deoxycytidylate deaminase zinc-binding region domain-containing protein | 0.0053 | 0.0149 | 0.19 |
Schistosoma mansoni | inositol monophosphatase | 0.0116 | 0.0499 | 0.0482 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0069 | 0.0239 | 0.0182 |
Echinococcus granulosus | thymidylate kinase | 0.0154 | 0.0711 | 0.0706 |
Trypanosoma brucei | apurinic/apyrimidinic endonuclease, putative | 0.006 | 0.019 | 0.0191 |
Schistosoma mansoni | hypothetical protein | 0.0512 | 0.2704 | 0.2692 |
Echinococcus multilocularis | Basic leucine zipper (bZIP) transcription | 0.0037 | 0.0063 | 0.0057 |
Onchocerca volvulus | Ribonuclease H1 homolog | 0.0092 | 0.0365 | 0.2115 |
Echinococcus granulosus | aldehyde dehydrogenase mitochondrial | 0.0062 | 0.0201 | 0.0195 |
Schistosoma mansoni | hypothetical protein | 0.0154 | 0.0711 | 0.0696 |
Brugia malayi | Intermediate filament tail domain containing protein | 0.0056 | 0.0167 | 0.0909 |
Trichomonas vaginalis | myo inositol monophosphatase, putative | 0.0116 | 0.0499 | 0.0452 |
Leishmania major | aldehyde dehydrogenase, mitochondrial precursor | 0.0062 | 0.0201 | 0.0143 |
Toxoplasma gondii | exonuclease III APE | 0.006 | 0.019 | 0.2487 |
Schistosoma mansoni | transcription factor LCR-F1 | 0.0037 | 0.0063 | 0.0046 |
Trypanosoma cruzi | thymidine kinase, putative | 0.1769 | 0.9697 | 1 |
Trypanosoma cruzi | cytidine deaminase-like protein | 0.0053 | 0.0149 | 0.0089 |
Echinococcus granulosus | beta LACTamase domain containing family member | 0.0037 | 0.0063 | 0.0058 |
Trypanosoma cruzi | thymidine kinase, putative | 0.1769 | 0.9697 | 1 |
Schistosoma mansoni | thymidylate kinase | 0.0154 | 0.0711 | 0.0696 |
Giardia lamblia | Cytidine deaminase | 0.0053 | 0.0149 | 0.0081 |
Entamoeba histolytica | glycogen phosphorylase, putative | 0.014 | 0.0637 | 0.0596 |
Leishmania major | thymidine kinase, putative | 0.1769 | 0.9697 | 1 |
Trypanosoma cruzi | cytidine deaminase-like protein, putative | 0.0053 | 0.0149 | 0.0089 |
Trypanosoma brucei | DNA polymerase kappa, putative | 0.0039 | 0.0071 | 0.0069 |
Entamoeba histolytica | deoxyuridine 5-triphosphate nucleotidohydrolase domain containing protein | 0.0069 | 0.0239 | 0.0182 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0062 | 0.02 | 0.0202 |
Brugia malayi | Inositol-1 | 0.0116 | 0.0499 | 0.2927 |
Loa Loa (eye worm) | thymidylate kinase | 0.0154 | 0.0711 | 0.428 |
Mycobacterium leprae | PROBABLE CYTIDINE DEAMINASE CDD (CYTIDINE AMINOHYDROLASE) (CYTIDINE NUCLEOSIDE DEAMINASE) | 0.0053 | 0.0149 | 0.1322 |
Schistosoma mansoni | intermediate filament proteins | 0.0056 | 0.0167 | 0.015 |
Echinococcus granulosus | survival motor neuron protein 1 | 0.0245 | 0.1219 | 0.1214 |
Trypanosoma brucei | thymidylate kinase, putative | 0.0154 | 0.0711 | 0.073 |
Mycobacterium ulcerans | thymidylate kinase | 0.0154 | 0.0711 | 1 |
Echinococcus granulosus | glycogen phosphorylase | 0.0325 | 0.1662 | 0.1658 |
Trypanosoma brucei | ingi protein (ORF1) | 0.0103 | 0.0428 | 0.0437 |
Loa Loa (eye worm) | intermediate filament tail domain-containing protein | 0.0056 | 0.0167 | 0.1002 |
Brugia malayi | beta-lactamase family protein | 0.0037 | 0.0063 | 0.0281 |
Echinococcus multilocularis | glycogen phosphorylase | 0.0325 | 0.1662 | 0.1658 |
Schistosoma mansoni | rab geranylgeranyl transferase alpha subunit | 0.0039 | 0.0071 | 0.0054 |
Loa Loa (eye worm) | ImpB/MucB/SamB family protein | 0.0039 | 0.0071 | 0.0428 |
Toxoplasma gondii | thymidylate kinase | 0.0154 | 0.0711 | 1 |
Mycobacterium ulcerans | aldehyde dehydrogenase | 0.0062 | 0.0201 | 0.2125 |
Trypanosoma brucei | DNA polymerase kappa, putative | 0.0039 | 0.0071 | 0.0069 |
Mycobacterium ulcerans | exodeoxyribonuclease III protein XthA | 0.006 | 0.019 | 0.1951 |
Echinococcus granulosus | DNA apurinic or apyrimidinic site lyase | 0.006 | 0.019 | 0.0184 |
Brugia malayi | hypothetical protein | 0.0054 | 0.0158 | 0.0858 |
Trichomonas vaginalis | thymidine kinase, putative | 0.1769 | 0.9697 | 1 |
Trypanosoma cruzi | thymidylate kinase, putative | 0.0154 | 0.0711 | 0.0673 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0069 | 0.0239 | 0.0182 |
Onchocerca volvulus | Glycogen phosphorylase homolog | 0.0325 | 0.1662 | 1 |
Entamoeba histolytica | deoxyuridine 5-triphosphate nucleotidohydrolase domain containing protein | 0.0069 | 0.0239 | 0.0182 |
Echinococcus multilocularis | dna polymerase kappa | 0.0039 | 0.0071 | 0.0066 |
Trypanosoma brucei | DNA polymerase IV, putative | 0.0039 | 0.0071 | 0.0069 |
Trypanosoma cruzi | apurinic/apyrimidinic endonuclease, putative | 0.006 | 0.019 | 0.0131 |
Echinococcus granulosus | cadherin EGF LAG seven pass G type receptor | 0.0034 | 0.0047 | 0.0041 |
Trypanosoma cruzi | DNA polymerase kappa, putative | 0.0039 | 0.0071 | 0.0008 |
Loa Loa (eye worm) | hypothetical protein | 0.0037 | 0.0063 | 0.038 |
Loa Loa (eye worm) | beta-lactamase | 0.0037 | 0.0063 | 0.038 |
Trichomonas vaginalis | set domain proteins, putative | 0.023 | 0.1136 | 0.1114 |
Mycobacterium tuberculosis | Inositol-1-monophosphatase SuhB | 0.0103 | 0.0431 | 0.329 |
Echinococcus granulosus | glycogen phosphorylase | 0.0325 | 0.1662 | 0.1658 |
Loa Loa (eye worm) | beta-LACTamase domain containing family member | 0.0037 | 0.0063 | 0.038 |
Echinococcus multilocularis | thymidine kinase | 0.1824 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0037 | 0.0063 | 0.038 |
Echinococcus granulosus | intermediate filament protein | 0.0056 | 0.0167 | 0.0161 |
Trypanosoma brucei | thymidine kinase | 0.1769 | 0.9697 | 1 |
Trypanosoma brucei | DNA polymerase IV, putative | 0.0039 | 0.0071 | 0.0069 |
Brugia malayi | ImpB/MucB/SamB family protein | 0.0039 | 0.0071 | 0.033 |
Trichomonas vaginalis | thymidine kinase, putative | 0.1769 | 0.9697 | 1 |
Schistosoma mansoni | phosphoglucomutase | 0.0092 | 0.0365 | 0.0349 |
Wolbachia endosymbiont of Brugia malayi | thymidylate kinase | 0.0154 | 0.0711 | 1 |
Echinococcus multilocularis | atpase aaa+ type core atpase aaa type core | 0.1681 | 0.9206 | 0.9206 |
Echinococcus granulosus | Mitotic checkpoint protein PRCC C terminal | 0.0141 | 0.064 | 0.0635 |
Loa Loa (eye worm) | hypothetical protein | 0.0055 | 0.0161 | 0.0968 |
Trichomonas vaginalis | thymidine kinase, putative | 0.1769 | 0.9697 | 1 |
Echinococcus multilocularis | Mitotic checkpoint protein PRCC, C terminal | 0.0141 | 0.064 | 0.0635 |
Echinococcus granulosus | Na+ dependent nucleoside transporter | 0.0338 | 0.1734 | 0.1729 |
Schistosoma mansoni | thymidine kinase | 0.1824 | 1 | 1 |
Loa Loa (eye worm) | GTP-binding regulatory protein Gs alpha-S chain | 0.0052 | 0.0146 | 0.0877 |
Entamoeba histolytica | hypothetical protein | 0.0069 | 0.0239 | 0.0182 |
Giardia lamblia | Deoxynucleoside kinase | 0.1588 | 0.8688 | 0.8952 |
Trichomonas vaginalis | cytidine deaminase, putative | 0.0053 | 0.0149 | 0.0089 |
Echinococcus granulosus | guanine nucleotide binding protein Gs subunit | 0.0052 | 0.0146 | 0.014 |
Schistosoma mansoni | family S12 unassigned peptidase (S12 family) | 0.0037 | 0.0063 | 0.0046 |
Schistosoma mansoni | hypothetical protein | 0.0512 | 0.2704 | 0.2692 |
Loa Loa (eye worm) | hypothetical protein | 0.0034 | 0.0047 | 0.028 |
Brugia malayi | cytidine deaminase, identical | 0.0053 | 0.0149 | 0.0802 |
Trypanosoma cruzi | thymidylate kinase, putative | 0.0154 | 0.0711 | 0.0673 |
Entamoeba histolytica | hypothetical protein | 0.0069 | 0.0239 | 0.0182 |
Mycobacterium tuberculosis | Possible DNA-damage-inducible protein P DinP (DNA polymerase V) (pol IV 2) (DNA nucleotidyltransferase (DNA-directed)) | 0.0039 | 0.0071 | 0.0071 |
Loa Loa (eye worm) | hypothetical protein | 0.0109 | 0.0459 | 0.2763 |
Entamoeba histolytica | glycogenphosphorylase, putative | 0.014 | 0.0637 | 0.0596 |
Schistosoma mansoni | glycogen phosphorylase | 0.014 | 0.0637 | 0.0621 |
Brugia malayi | Iron-sulfur cluster assembly accessory protein | 0.005 | 0.0134 | 0.0709 |
Trypanosoma brucei | DNA polymerase kappa, putative | 0.0039 | 0.0071 | 0.0069 |
Trichomonas vaginalis | myo inositol monophosphatase, putative | 0.0116 | 0.0499 | 0.0452 |
Brugia malayi | cytoplasmic intermediate filament protein | 0.003 | 0.0022 | 0.0032 |
Leishmania major | myo-inositol-1(or 4)-monophosphatase 1, putative | 0.0116 | 0.0499 | 0.0452 |
Schistosoma mansoni | glycogen phosphorylase | 0.0325 | 0.1662 | 0.1648 |
Echinococcus granulosus | NADH ubiquinone oxidoreductase 42 kDa subunit | 0.0069 | 0.0239 | 0.0233 |
Leishmania major | DNA polymerase kappa, putative | 0.0039 | 0.0071 | 0.0008 |
Trypanosoma cruzi | cysteine peptidase, putative | 0.0062 | 0.02 | 0.0142 |
Echinococcus multilocularis | terminal deoxycytidyl transferase rev1 | 0.0039 | 0.0071 | 0.0066 |
Trichomonas vaginalis | ap endonuclease, putative | 0.006 | 0.019 | 0.0131 |
Trypanosoma cruzi | major cysteine proteinase, putative | 0.0049 | 0.0127 | 0.0066 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0062 | 0.02 | 0.0202 |
Schistosoma mansoni | survival motor neuron protein | 0.005 | 0.0134 | 0.0117 |
Schistosoma mansoni | hypothetical protein | 0.0162 | 0.0756 | 0.074 |
Giardia lamblia | Thymidine kinase | 0.1769 | 0.9697 | 1 |
Echinococcus multilocularis | ribonuclease H1 | 0.0092 | 0.0365 | 0.0359 |
Trypanosoma cruzi | PAB1-binding protein , putative | 0.0054 | 0.0158 | 0.0099 |
Echinococcus multilocularis | beta LACTamase domain containing family member | 0.0037 | 0.0063 | 0.0058 |
Entamoeba histolytica | myo-inositol monophosphatase, putative | 0.0116 | 0.0499 | 0.0452 |
Trypanosoma cruzi | cruzipain precursor, putative | 0.0062 | 0.02 | 0.0142 |
Trypanosoma cruzi | DNA polymerase kappa, putative | 0.0039 | 0.0071 | 0.0008 |
Brugia malayi | RNase H family protein | 0.0092 | 0.0365 | 0.2115 |
Schistosoma mansoni | phosphoglucomutase | 0.0092 | 0.0365 | 0.0349 |
Plasmodium vivax | hypothetical protein, conserved | 0.0037 | 0.0063 | 0.0666 |
Echinococcus granulosus | arachidonate 5 lipoxygenase | 0.0057 | 0.0174 | 0.0168 |
Trypanosoma cruzi | DNA polymerase kappa, putative | 0.0039 | 0.0071 | 0.0008 |
Brugia malayi | hypothetical protein | 0.0245 | 0.1219 | 0.7305 |
Schistosoma mansoni | hypothetical protein | 0.0074 | 0.0268 | 0.0252 |
Loa Loa (eye worm) | hypothetical protein | 0.0054 | 0.0158 | 0.0951 |
Schistosoma mansoni | hypothetical protein | 0.0141 | 0.064 | 0.0624 |
Trypanosoma brucei | retrotransposon hot spot protein 4 (RHS4), interrupted | 0.0103 | 0.0428 | 0.0437 |
Schistosoma mansoni | hypothetical protein | 0.0034 | 0.0047 | 0.003 |
Schistosoma mansoni | hypothetical protein | 0.0034 | 0.0047 | 0.003 |
Brugia malayi | hypothetical protein | 0.0037 | 0.0063 | 0.028 |
Onchocerca volvulus | 0.0037 | 0.0063 | 0.0281 | |
Echinococcus multilocularis | glycogen phosphorylase | 0.0325 | 0.1662 | 0.1658 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0069 | 0.0239 | 0.0182 |
Treponema pallidum | ribonuclease H (rnhA) | 0.0092 | 0.0365 | 0.3359 |
Trichomonas vaginalis | DNA polymerase eta, putative | 0.0039 | 0.0071 | 0.0008 |
Echinococcus granulosus | cytidine deaminase | 0.0053 | 0.0149 | 0.0143 |
Trypanosoma brucei | DNA polymerase kappa, putative | 0.0039 | 0.0071 | 0.0069 |
Loa Loa (eye worm) | hypothetical protein | 0.0074 | 0.0268 | 0.1614 |
Entamoeba histolytica | glycogen phosphorylase, putative | 0.0325 | 0.1662 | 0.166 |
Trypanosoma brucei | DNA polymerase kappa, putative | 0.0039 | 0.0071 | 0.0069 |
Trypanosoma cruzi | cysteine peptidase, putative | 0.0062 | 0.02 | 0.0142 |
Trypanosoma cruzi | DNA polymerase kappa, putative | 0.0039 | 0.0071 | 0.0008 |
Echinococcus granulosus | terminal deoxycytidyl transferase rev1 | 0.0039 | 0.0071 | 0.0066 |
Loa Loa (eye worm) | hypothetical protein | 0.0037 | 0.0063 | 0.038 |
Trypanosoma cruzi | ribonuclease H1, putative | 0.0092 | 0.0365 | 0.0313 |
Loa Loa (eye worm) | deoxynucleoside kinase | 0.0069 | 0.0239 | 0.1435 |
Echinococcus multilocularis | histone lysine methyltransferase setb histone lysine methyltransferase eggless | 0.0029 | 0.0017 | 0.0011 |
Mycobacterium ulcerans | extragenic suppressor protein SuhB | 0.0116 | 0.0499 | 0.6716 |
Onchocerca volvulus | Putative thymidylate kinase | 0.0154 | 0.0711 | 0.4221 |
Entamoeba histolytica | Thymidylate kinase, putative | 0.0154 | 0.0711 | 0.0673 |
Echinococcus multilocularis | dna polymerase eta | 0.0039 | 0.0071 | 0.0066 |
Schistosoma mansoni | hypothetical protein | 0.0034 | 0.0047 | 0.003 |
Echinococcus granulosus | Thymidine kinase 2 mitochondrial | 0.1824 | 1 | 1 |
Echinococcus multilocularis | aldehyde dehydrogenase, mitochondrial | 0.0062 | 0.0201 | 0.0195 |
Echinococcus granulosus | ribonuclease H1 | 0.0092 | 0.0365 | 0.0359 |
Mycobacterium tuberculosis | Probable exodeoxyribonuclease III protein XthA (exonuclease III) (EXO III) (AP endonuclease VI) | 0.006 | 0.019 | 0.1131 |
Echinococcus multilocularis | Glycosyl transferase, family 35 | 0.0325 | 0.1662 | 0.1658 |
Trypanosoma brucei | unspecified product | 0.0039 | 0.0071 | 0.0069 |
Mycobacterium ulcerans | aldehyde dehydrogenase | 0.0062 | 0.0201 | 0.2125 |
Schistosoma mansoni | aldehyde dehydrogenase | 0.0062 | 0.0201 | 0.0184 |
Mycobacterium leprae | probable thymidylate kinase Tmk (dTMP KINASE) (THYMIDYLIC ACID KINASE) (TMPK) | 0.0154 | 0.0711 | 1 |
Leishmania major | DNA polymerase kappa, putative,DNA polymerase IV, putative | 0.0039 | 0.0071 | 0.0008 |
Trypanosoma cruzi | cysteine peptidase, putative | 0.0062 | 0.02 | 0.0142 |
Trichomonas vaginalis | thymidylate kinase, putative | 0.0154 | 0.0711 | 0.0673 |
Schistosoma mansoni | DNA polymerase eta | 0.0039 | 0.0071 | 0.0054 |
Brugia malayi | calcium-independent alpha-latrotoxin receptor 2, putative | 0.0034 | 0.0047 | 0.018 |
Echinococcus granulosus | guanine nucleotide binding protein Gs subunit | 0.0052 | 0.0146 | 0.014 |
Echinococcus granulosus | Glycosyl transferase family 35 | 0.0325 | 0.1662 | 0.1658 |
Echinococcus granulosus | inositol monophosphatase 1 | 0.0116 | 0.0499 | 0.0493 |
Activity type | Activity value | Assay description | Source | Reference |
---|---|---|---|---|
IC50 (binding) | > 100 uM | In vitro inhibitory concentration required to block recombinant human prostaglandin G/H synthase 1 (COX-1) | ChEMBL. | 9135032 |
IC50 (binding) | = 100 uM | In vitro inhibitory concentration required to block human recombinant prostaglandin G/H synthase 2 (COX-2) | ChEMBL. | 9135032 |
IC50 (binding) | > 100 uM | In vitro inhibitory concentration required to block recombinant human prostaglandin G/H synthase 1 (COX-1) | ChEMBL. | 9135032 |
IC50 (binding) | = 100 uM | In vitro inhibitory concentration required to block human recombinant prostaglandin G/H synthase 2 (COX-2) | ChEMBL. | 9135032 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.
1 literature reference was collected for this gene.