Detailed information for compound 378813

Basic information

Technical information
  • Name: Unnamed compound
  • MW: 1243.75 | Formula: C53H83ClN12O20
  • H donors: 18 H acceptors: 18 LogP: -6.51 Rotable bonds: 27
    Rule of 5 violations (Lipinski): 4
  • SMILES: NCCCC[C@@H]1NC(=O)[C@@H](CC(=O)O)NC(=O)[C@@H](CCN)NC(=O)[C@@H](COC(=O)[C@@H](NC(=O)[C@@H](NC(=O)C(=CC)NC(=O)[C@@H](NC(=O)[C@H](NC1=O)CCN)[C@H](O)C)[C@H](C(=O)O)O)[C@H](CCl)O)NC(=O)CC(Cc1cccc(c1)OCCCCCC)O
  • InChi: 1S/C53H83ClN12O20/c1-4-6-7-10-20-85-30-13-11-12-28(22-30)21-29(68)23-38(70)58-36-26-86-53(84)41(37(69)25-54)65-51(81)42(43(73)52(82)83)66-44(74)31(5-2)59-50(80)40(27(3)67)64-47(77)34(16-19-57)61-45(75)32(14-8-9-17-55)60-48(78)35(24-39(71)72)63-46(76)33(15-18-56)62-49(36)79/h5,11-13,22,27,29,32-37,40-43,67-69,73H,4,6-10,14-21,23-26,55-57H2,1-3H3,(H,58,70)(H,59,80)(H,60,78)(H,61,75)(H,62,79)(H,63,76)(H,64,77)(H,65,81)(H,66,74)(H,71,72)(H,82,83)/b31-5-/t27?,29?,32-,33-,34-,35-,36+,37-,40+,41-,42+,43+/m1/s1
  • InChiKey: CGXXGAOMQPLCEL-HHLPRTEUSA-N  


Substructure search Similarity search

Network

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Synonyms

No synonyms found for this compound

Targets

Known targets for this compound

No curated genes were found associated with this compound

Predicted pathogen targets for this compound

By orthology
No druggable targets predicted by orthology data
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Echinococcus granulosus SH2 domain containing adapter protein F 0.0037 0.0042 0.0061
Mycobacterium tuberculosis Probable chain -fatty-acid-CoA ligase FadD13 (fatty-acyl-CoA synthetase) 0.0027 0.0021 0.0021
Onchocerca volvulus 0.0056 0.0079 0.0759
Echinococcus granulosus diuretic hormone 44 receptor GPRdih2 0.008 0.0126 0.0185
Schistosoma mansoni tyrosine kinase 0.0049 0.0064 0.0094
Trichomonas vaginalis cat eye syndrome critical region protein 2, cscr2, putative 0.005 0.0066 0.0712
Echinococcus granulosus retinal guanylyl cyclase 2 0.0049 0.0064 0.0094
Echinococcus multilocularis tyrosine kinase 0.0086 0.0138 0.0202
Loa Loa (eye worm) hypothetical protein 0.0021 0.0009 0.0114
Trichomonas vaginalis TKL family protein kinase 0.0049 0.0064 0.0692
Entamoeba histolytica protein kinase domain containing protein 0.0049 0.0064 0.0505
Schistosoma mansoni microtubule-associated protein tau 0.3471 0.6799 1
Echinococcus multilocularis tyrosine protein phosphatase non receptor type 0.0037 0.0042 0.0061
Schistosoma mansoni nuclear receptor 2DBD-gamma 0.0044 0.0055 0.0081
Brugia malayi hypothetical protein 0.0176 0.0315 0.388
Trichomonas vaginalis chromobox protein, putative 0.0044 0.0054 0.0584
Mycobacterium tuberculosis Probable ATP-dependent CLP protease proteolytic subunit 1 ClpP1 (endopeptidase CLP) 0.006 0.0086 0.0086
Echinococcus multilocularis phosphatidylinositol 3 kinase regulatory subunit 0.0037 0.0042 0.0061
Echinococcus multilocularis nuclear receptor subfamily 4 group A 0.0021 0.0009 0.0014
Echinococcus multilocularis COUP TF:Svp nuclear hormone receptor 0.0044 0.0055 0.0081
Trichomonas vaginalis conserved hypothetical protein 0.002 0.0007 0.0073
Brugia malayi Variant SH3 domain containing protein 0.0037 0.0042 0.0515
Schistosoma mansoni tar DNA-binding protein 0.0066 0.0098 0.0144
Brugia malayi Nuclear hormone receptor family member nhr-31 0.0044 0.0055 0.0678
Echinococcus multilocularis Transcription factor, JmjC domain containing protein 0.0198 0.0358 0.0527
Echinococcus multilocularis solute carrier family 2 facilitated glucose 0.0097 0.016 0.0236
Echinococcus granulosus tensin 0.0037 0.0042 0.0061
Schistosoma mansoni growth factor receptor-bound protein 0.0037 0.0042 0.0061
Loa Loa (eye worm) hypothetical protein 0.0029 0.0026 0.0322
Entamoeba histolytica hypothetical protein 0.0049 0.0064 0.0505
Onchocerca volvulus 0.0032 0.0031 0.0235
Echinococcus multilocularis signal transduction protein lnk realted 0.0037 0.0042 0.0061
Trypanosoma brucei THT1 - hexose transporter, putative 0.003 0.0028 0.3453
Echinococcus multilocularis ecdysone induced protein 78C 0.0044 0.0055 0.0081
Echinococcus multilocularis FTZ F1 alpha 0.0044 0.0055 0.0081
Trypanosoma cruzi calpain cysteine peptidase, putative 0.0017 0.0002 0.0298
Echinococcus multilocularis SH2 domain containing protein 7 0.0037 0.0042 0.0061
Schistosoma mansoni tyrosine kinase 0.0049 0.0064 0.0094
Echinococcus granulosus tensin C1 domain containing phosphatase 0.0037 0.0042 0.0061
Trypanosoma brucei PAB1-binding protein , putative 0.0029 0.0026 0.3245
Brugia malayi SH2 domain containing protein 0.0086 0.0138 0.1696
Loa Loa (eye worm) TK/FER protein kinase 0.0086 0.0138 0.1696
Schistosoma mansoni chimerin-related rho-gtpase-activating protein 0.0037 0.0042 0.0061
Echinococcus multilocularis mitogen activated protein kinase 0.0057 0.0081 0.0119
Loa Loa (eye worm) nuclear hormone receptor family member nhr-41 0.0044 0.0055 0.0678
Echinococcus multilocularis protein kinase 0.0049 0.0064 0.0094
Brugia malayi CXXC zinc finger family protein 0.0063 0.0093 0.1144
Schistosoma mansoni steroid hormone receptor ad4bp 0.0044 0.0055 0.0081
Loa Loa (eye worm) hypothetical protein 0.0037 0.0042 0.0515
Mycobacterium ulcerans hypothetical protein 0.0027 0.0021 0.0021
Echinococcus granulosus tyrosine protein phosphatase non receptor type 0.0037 0.0042 0.0061
Echinococcus multilocularis diuretic hormone 44 receptor GPRdih2 0.008 0.0126 0.0185
Entamoeba histolytica hypothetical protein 0.0049 0.0064 0.0505
Trichomonas vaginalis chromobox protein, putative 0.0072 0.0111 0.1192
Schistosoma mansoni tyrosine kinase 0.0049 0.0064 0.0094
Echinococcus granulosus SHC transforming protein 3 0.0037 0.0042 0.0061
Brugia malayi photoreceptor-specific nuclear receptor 0.0044 0.0055 0.0678
Entamoeba histolytica protein tyrosine kinase domain-containing protein 0.0049 0.0064 0.0505
Onchocerca volvulus Heterochromatin protein 1 homolog 0.0041 0.0048 0.0423
Schistosoma mansoni thyroid hormone receptor 0.0044 0.0055 0.0081
Schistosoma mansoni nuclear receptor 0.0021 0.0009 0.0014
Toxoplasma gondii histone lysine methyltransferase SET1 0.0126 0.0217 1
Plasmodium falciparum JmjC domain-containing protein, putative 0.002 0.0007 0.0007
Echinococcus multilocularis cpg binding protein 0.0067 0.01 0.0147
Echinococcus granulosus calpain 5 0.0017 0.0002 0.0004
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0026 0.002 0.0214
Echinococcus granulosus suppressor of cytokine signaling 7 0.0037 0.0042 0.0061
Brugia malayi bone morphogenetic protein type 1 receptor 0.0049 0.0064 0.0791
Echinococcus granulosus integrin linked protein kinase 0.0049 0.0064 0.0094
Giardia lamblia Kinase 0.0049 0.0064 0.7344
Echinococcus multilocularis ephrin type A receptor 4 A 0.0049 0.0064 0.0094
Trichomonas vaginalis CMGC family protein kinase 0.0057 0.0081 0.0869
Echinococcus granulosus lysine specific demethylase 6a 0.002 0.0007 0.001
Loa Loa (eye worm) hypothetical protein 0.0049 0.0064 0.0791
Echinococcus granulosus macrophage colony stimulating factor 1 receptor 0.0049 0.0064 0.0094
Trypanosoma cruzi calpain-like cysteine peptidase, putative 0.0017 0.0002 0.0298
Loa Loa (eye worm) variant SH3 domain-containing protein 0.0037 0.0042 0.0515
Echinococcus multilocularis tyrosine protein phosphatase non receptor type 0.0037 0.0042 0.0061
Trypanosoma cruzi hexose transporter, putative 0.003 0.0028 0.3453
Schistosoma mansoni tyrosine protein kinase fes (fps) (ptk group IV) 0.0049 0.0064 0.0094
Loa Loa (eye worm) TK protein kinase 0.0086 0.0138 0.1696
Brugia malayi Protein kinase domain containing protein 0.0086 0.0138 0.1696
Echinococcus granulosus tyrosine protein kinase csk 0.0049 0.0064 0.0094
Brugia malayi hypothetical protein 0.0029 0.0026 0.0322
Trichomonas vaginalis TKL family protein kinase 0.0049 0.0064 0.0692
Entamoeba histolytica protein kinase, putative 0.0049 0.0064 0.0505
Echinococcus granulosus ecdysone induced protein 78C 0.0044 0.0055 0.0081
Toxoplasma gondii isocitrate dehydrogenase 0.0047 0.0062 0.2843
Echinococcus multilocularis Nuclear hormone receptor HR96 0.0021 0.0009 0.0014
Trypanosoma cruzi STE/STE11 serine/threonine-protein kinase, putative 0.0049 0.0065 0.8089
Loa Loa (eye worm) RNA recognition domain-containing protein domain-containing protein 0.0066 0.0098 0.1204
Brugia malayi Protein kinase domain containing protein 0.0049 0.0064 0.0791
Schistosoma mansoni transcription factor LCR-F1 0.0037 0.0042 0.0061
Echinococcus multilocularis N chimaerin 0.0037 0.0042 0.0061
Loa Loa (eye worm) hypothetical protein 0.0023 0.0014 0.0174
Mycobacterium leprae ATP-dependent Clp protease proteolytic subunit 1 0.0031 0.003 0.0752
Schistosoma mansoni protein kinase 0.0049 0.0064 0.0094
Loa Loa (eye worm) TK/FER protein kinase 0.0086 0.0138 0.1696
Loa Loa (eye worm) variant SH3 domain-containing protein 0.0037 0.0042 0.0515
Echinococcus multilocularis mixed lineage leukemia protein mll 0.0018 0.0004 0.0005
Schistosoma mansoni coup transcription factor 0.0044 0.0055 0.0081
Mycobacterium ulcerans acyl-CoA synthetase 0.0027 0.0021 0.0021
Entamoeba histolytica hypothetical protein 0.0049 0.0064 0.0505
Onchocerca volvulus 0.0049 0.0064 0.0598
Loa Loa (eye worm) nuclear hormone receptor family member nhr-40 0.0044 0.0055 0.0678
Trypanosoma cruzi mitogen-activated protein kinase 11, putative 0.0057 0.0081 1
Trichomonas vaginalis br serine/threonine-protein kinase, putative 0.0049 0.0064 0.0692
Echinococcus multilocularis tar DNA binding protein 0.0066 0.0098 0.0144
Loa Loa (eye worm) hypothetical protein 0.0044 0.0055 0.0678
Brugia malayi calpain 5 0.0017 0.0002 0.003
Onchocerca volvulus 0.0049 0.0064 0.0598
Echinococcus multilocularis tyrosine protein kinase 0.0049 0.0064 0.0094
Trypanosoma cruzi calpain-like cysteine peptidase, putative 0.0017 0.0002 0.0298
Loa Loa (eye worm) TAR-binding protein 0.0066 0.0098 0.1204
Echinococcus multilocularis hypothetical protein 0.0017 0.0002 0.0004
Schistosoma mansoni ephrin receptor 0.0049 0.0064 0.0094
Brugia malayi jmjC domain containing protein 0.002 0.0007 0.0083
Trichomonas vaginalis TKL family protein kinase 0.0049 0.0064 0.0692
Echinococcus granulosus tar DNA binding protein 0.0066 0.0098 0.0144
Loa Loa (eye worm) jmjC domain-containing protein 0.002 0.0007 0.0083
Trypanosoma brucei calpain-like protein, putative 0.0017 0.0002 0.0298
Loa Loa (eye worm) PHD-finger family protein 0.006 0.0087 0.1077
Schistosoma mansoni calpain C (C02 family) 0.0017 0.0002 0.0004
Echinococcus multilocularis tyrosine protein kinase csk 0.0049 0.0064 0.0094
Trypanosoma cruzi hexose transporter, putative 0.003 0.0028 0.3453
Brugia malayi nuclear receptor NHR-88 0.0044 0.0055 0.0678
Mycobacterium tuberculosis Probable isocitrate dehydrogenase [NADP] Icd1 (oxalosuccinate decarboxylase) (IDH) (NADP+-specific ICDH) (IDP) 0.0047 0.0062 0.0062
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0044 0.0055 0.0678
Treponema pallidum ATP-dependent Clp protease proteolytic subunit 0.0031 0.003 0.204
Toxoplasma gondii histone lysine demethylase JMJD6a 0.002 0.0007 0.0312
Brugia malayi Protein kinase domain containing protein 0.0049 0.0064 0.0791
Brugia malayi SH2 domain containing protein 0.0037 0.0042 0.0515
Mycobacterium ulcerans aldehyde dehydrogenase 0.0068 0.0102 0.0102
Entamoeba histolytica protein kinase, putative 0.0049 0.0064 0.0505
Loa Loa (eye worm) TK protein kinase 0.0049 0.0064 0.0791
Plasmodium falciparum acyl-CoA synthetase 0.002 0.0007 0.0007
Trichomonas vaginalis STE family protein kinase 0.0049 0.0064 0.0692
Echinococcus multilocularis tyrosine protein kinase Fgr 0.0086 0.0138 0.0202
Brugia malayi Tyrosine-protein kinase PR2 0.0049 0.0064 0.0791
Entamoeba histolytica protein kinase domain containing protein 0.0049 0.0065 0.0513
Echinococcus multilocularis lysine specific demethylase 5A 0.0073 0.0112 0.0165
Echinococcus granulosus muscleblind protein 0.0402 0.0759 0.1117
Schistosoma mansoni tyrosine kinase 0.0049 0.0064 0.0094
Loa Loa (eye worm) steroid hormone receptor 0.0044 0.0055 0.0678
Trichomonas vaginalis TKL family protein kinase 0.0049 0.0064 0.0692
Loa Loa (eye worm) hypothetical protein 0.0023 0.0014 0.0174
Schistosoma mansoni jumonji domain containing protein 0.0157 0.0278 0.0409
Brugia malayi Protein kinase domain containing protein 0.0049 0.0064 0.0791
Echinococcus granulosus jumonji domain containing 1A 0.002 0.0007 0.001
Trichomonas vaginalis TKL family protein kinase 0.0049 0.0064 0.0692
Brugia malayi calpain family protein 1 0.0058 0.0083 0.102
Echinococcus multilocularis tensin 0.0037 0.0042 0.0061
Entamoeba histolytica protein kinase, putative 0.0049 0.0064 0.0505
Loa Loa (eye worm) hypothetical protein 0.0049 0.0064 0.0791
Entamoeba histolytica tyrosine kinase, putative 0.0049 0.0064 0.0505
Loa Loa (eye worm) hypothetical protein 0.0027 0.0021 0.0253
Echinococcus granulosus NADP dependent isocitrate dehydrogenase 0.0047 0.0062 0.0091
Trichomonas vaginalis TKL family protein kinase 0.0049 0.0064 0.0692
Trypanosoma brucei kinesin, putative 0.0017 0.0002 0.0298
Entamoeba histolytica protein kinase, putative 0.0049 0.0064 0.0505
Loa Loa (eye worm) TK protein kinase 0.0049 0.0064 0.0791
Schistosoma mansoni hypothetical protein 0.006 0.0087 0.0129
Echinococcus granulosus Nuclear hormone receptor family member nhr 41 0.0044 0.0055 0.0081
Plasmodium vivax tyrosine kinase-like protein, putative 0.0049 0.0064 0.0064
Echinococcus multilocularis aldehyde dehydrogenase, mitochondrial 0.0068 0.0102 0.015
Trypanosoma brucei glucose transporter, putative 0.003 0.0028 0.3453
Echinococcus multilocularis mitogen activated protein kinase 3 0.0057 0.0081 0.0119
Entamoeba histolytica protein kinase, putative 0.0049 0.0064 0.0505
Mycobacterium ulcerans 3-oxoacyl-ACP synthase 0.5097 1 1
Brugia malayi jmjC domain containing protein 0.0198 0.0358 0.4415
Trichomonas vaginalis protein tyrosine kinase, putative 0.0049 0.0064 0.0692
Echinococcus granulosus JmjC domain containing protein 4 0.002 0.0007 0.001
Trichomonas vaginalis conserved hypothetical protein 0.0041 0.0048 0.0518
Entamoeba histolytica hypothetical protein 0.0049 0.0064 0.0505
Loa Loa (eye worm) hypothetical protein 0.0032 0.0031 0.038
Trichomonas vaginalis TKL family protein kinase 0.0049 0.0064 0.0692
Loa Loa (eye worm) hypothetical protein 0.0037 0.0042 0.0515
Loa Loa (eye worm) hypothetical protein 0.0173 0.0309 0.3805
Echinococcus multilocularis macrophage colony stimulating factor 1 receptor 0.0049 0.0064 0.0094
Entamoeba histolytica hypothetical protein 0.0049 0.0064 0.0505
Brugia malayi Protein kinase domain containing protein 0.0049 0.0064 0.0791
Plasmodium vivax beta-ketoacyl-acyl carrier protein synthase III precursor, putative 0.5097 1 1
Plasmodium falciparum conserved Plasmodium membrane protein, unknown function 0.0024 0.0015 0.0015
Loa Loa (eye worm) TK/ALK protein kinase 0.0049 0.0064 0.0791
Loa Loa (eye worm) hypothetical protein 0.0037 0.0042 0.0515
Schistosoma mansoni ubiquitously transcribed sex (X/Y) chromosome tetratricopeptide repeat protein-related 0.002 0.0007 0.001
Onchocerca volvulus 0.0037 0.0042 0.0355
Brugia malayi hypothetical protein 0.0021 0.0009 0.0114
Echinococcus granulosus FTZ F1 alpha 0.0044 0.0055 0.0081
Mycobacterium tuberculosis Fatty-acid-AMP ligase FadD30 (fatty-acid-AMP synthetase) (fatty-acid-AMP synthase) 0.002 0.0007 0.0007
Schistosoma mansoni tyrosine protein kinase 0.0049 0.0064 0.0094
Brugia malayi nuclear receptor NHR-88 0.0021 0.0009 0.0114
Entamoeba histolytica tyrosine kinase, putative 0.0049 0.0064 0.0505
Trichomonas vaginalis TKL family protein kinase 0.0049 0.0064 0.0692
Loa Loa (eye worm) hypothetical protein 0.0023 0.0014 0.0174
Schistosoma mansoni tyrosine kinase 0.0049 0.0064 0.0094
Brugia malayi STAT protein, DNA binding domain containing protein 0.0037 0.0042 0.0515
Loa Loa (eye worm) TK/FER protein kinase 0.0086 0.0138 0.1696
Loa Loa (eye worm) CXXC zinc finger family protein 0.0063 0.0093 0.1144
Loa Loa (eye worm) pigment dispersing factor receptor c 0.0253 0.0466 0.5746
Echinococcus granulosus tyrosine protein kinase HCK 0.0049 0.0064 0.0094
Toxoplasma gondii protein kinase domain-containing protein 0.0049 0.0064 0.296
Trichomonas vaginalis TKL family protein kinase 0.0049 0.0064 0.0692
Trichomonas vaginalis TKL family protein kinase 0.0049 0.0064 0.0692
Entamoeba histolytica protein tyrosine kinase domain-containing protein 0.0049 0.0064 0.0505
Loa Loa (eye worm) TK/ABL protein kinase 0.0086 0.0138 0.1696
Brugia malayi Latrophilin receptor protein 2 0.008 0.0126 0.1551
Echinococcus multilocularis nuclear receptor subfamily 1 group D 0.0023 0.0014 0.0021
Entamoeba histolytica protein kinase, putative 0.0049 0.0064 0.0505
Schistosoma mansoni tyrosine kinase 0.0049 0.0064 0.0094
Brugia malayi tRNA modification GTPase TrmE family protein 0.0037 0.0042 0.0515
Schistosoma mansoni growth factor receptor-bound protein 0.0037 0.0042 0.0061
Trypanosoma brucei THT1 - hexose transporter, putative 0.003 0.0028 0.3453
Echinococcus granulosus cadherin EGF LAG seven pass G type receptor 0.008 0.0126 0.0185
Trichomonas vaginalis conserved hypothetical protein 0.0049 0.0064 0.0692
Echinococcus multilocularis raf serine:threonine protein kinase 0.0049 0.0064 0.0094
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0044 0.0055 0.0678
Brugia malayi ephrin receptor 1 precursor 0.0049 0.0064 0.0791
Toxoplasma gondii histone lysine methyltransferase SET/SUV39 0.0063 0.0092 0.4226
Echinococcus multilocularis calpain family protein 1, d 0.0041 0.0049 0.0072
Schistosoma mansoni tensin-related 0.0037 0.0042 0.0061
Echinococcus granulosus phosphatidylinositol 3 kinase regulatory subunit 0.0037 0.0042 0.0061
Toxoplasma gondii WD domain, G-beta repeat-containing protein 0.002 0.0007 0.0334
Loa Loa (eye worm) nuclear hormone receptor family member nhr-1 0.0044 0.0055 0.0678
Entamoeba histolytica tyrosine kinase, putative 0.0049 0.0064 0.0505
Echinococcus granulosus histone acetyltransferase KAT2B 0.0164 0.0291 0.0429
Entamoeba histolytica tyrosine kinase, putative 0.0049 0.0064 0.0505
Loa Loa (eye worm) hypothetical protein 0.0041 0.0049 0.0601
Entamoeba histolytica protein kinase, putative 0.0049 0.0064 0.0505
Schistosoma mansoni serine/threonine protein kinase 0.0049 0.0064 0.0094
Plasmodium vivax acyl-CoA synthetase, putative 0.002 0.0007 0.0007
Loa Loa (eye worm) TKL/MLK/ILK protein kinase 0.0049 0.0064 0.0791
Brugia malayi Protein kinase domain containing protein 0.0049 0.0064 0.0791
Trichomonas vaginalis TKL family protein kinase 0.0049 0.0064 0.0692
Echinococcus multilocularis tensin 0.0037 0.0042 0.0061
Echinococcus granulosus N chimaerin 0.0037 0.0042 0.0061
Mycobacterium leprae PROBABLE ATP-DEPENDENT CLP PROTEASE PROTEOLYTIC SUBUNIT 1 CLPP1 (ENDOPEPTIDASE CLP) 0.006 0.0086 0.5139
Entamoeba histolytica protein tyrosine kinase domain-containing protein 0.0049 0.0064 0.0505
Onchocerca volvulus 0.0086 0.0138 0.1398
Echinococcus multilocularis epidermal growth factor receptor 0.0049 0.0064 0.0094
Loa Loa (eye worm) hypothetical protein 0.0037 0.0042 0.0515
Trichomonas vaginalis TKL family protein kinase 0.0049 0.0064 0.0692
Schistosoma mansoni serine/threonine protein kinase 0.0057 0.0081 0.0119
Entamoeba histolytica serine/threonine kinase, putative 0.0049 0.0064 0.0505
Entamoeba histolytica protein kinase domain containing protein 0.0049 0.0064 0.0505
Loa Loa (eye worm) nuclear hormone receptor 0.0021 0.0009 0.0114
Onchocerca volvulus 0.0086 0.0138 0.1398
Echinococcus granulosus melanoma receptor tyrosine protein kinase 0.0049 0.0064 0.0094
Trypanosoma cruzi isocitrate dehydrogenase [NADP], mitochondrial precursor, putative 0.0047 0.0062 0.7649
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD5 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0019 0.0005 0.0005
Brugia malayi PHD-finger family protein 0.0023 0.0014 0.0177
Mycobacterium ulcerans long-chain fatty-acid CoA ligase 0.0027 0.0021 0.0021
Schistosoma mansoni family C2 unassigned peptidase (C02 family) 0.0061 0.0089 0.013
Entamoeba histolytica hypothetical protein 0.0037 0.0042 0.0329
Entamoeba histolytica protein kinase, putative 0.0018 0.0003 0.0027
Echinococcus multilocularis tyrosine protein kinase csk 0.0049 0.0064 0.0094
Echinococcus multilocularis growth factor receptor bound protein 2 0.0037 0.0042 0.0061
Loa Loa (eye worm) latrophilin receptor protein 2 0.008 0.0126 0.1551
Echinococcus multilocularis NCK adaptor protein 0.0037 0.0042 0.0061
Trichomonas vaginalis ankyrin repeat-containing protein, putative 0.0049 0.0064 0.0692
Loa Loa (eye worm) hypothetical protein 0.0037 0.0042 0.0515
Loa Loa (eye worm) hypothetical protein 0.0049 0.0064 0.0791
Brugia malayi Protein kinase domain containing protein 0.0049 0.0064 0.0791
Entamoeba histolytica protein tyrosine kinase domain-containing protein 0.0049 0.0064 0.0505
Echinococcus multilocularis tyrosine protein kinase Fes:Fps 0.0049 0.0064 0.0094
Onchocerca volvulus 0.0063 0.0093 0.091
Schistosoma mansoni retinoic acid receptor RXR 0.0044 0.0055 0.0081
Echinococcus granulosus nuclear receptor subfamily 4 group A 0.0021 0.0009 0.0014
Loa Loa (eye worm) TK/FER protein kinase 0.0086 0.0138 0.1696
Echinococcus granulosus tyrosine protein kinase pr2 0.0049 0.0064 0.0094
Schistosoma mansoni tyrosine kinase 0.0086 0.0138 0.0202
Trichomonas vaginalis conserved hypothetical protein 0.003 0.0028 0.03
Echinococcus granulosus calpain A 0.0017 0.0002 0.0004
Mycobacterium ulcerans aldehyde dehydrogenase 0.0068 0.0102 0.0102
Echinococcus multilocularis tyrosine protein kinase csk 0.0049 0.0064 0.0094
Onchocerca volvulus Steroid hormone receptor family member cnr14 homolog 0.0044 0.0055 0.0499
Loa Loa (eye worm) jmjC domain-containing protein 0.0077 0.012 0.1473
Loa Loa (eye worm) hypothetical protein 0.0027 0.0021 0.0253
Schistosoma mansoni serine/threonine protein kinase 0.0049 0.0064 0.0094
Trichomonas vaginalis TKL family protein kinase 0.0049 0.0064 0.0692
Echinococcus granulosus activated cdc42 kinase 1 0.0049 0.0064 0.0094
Echinococcus granulosus kinase suppressor of Ras 1 0.0049 0.0064 0.0094
Entamoeba histolytica tyrosine kinase, putative 0.0049 0.0064 0.0505
Onchocerca volvulus Suppressor of cytokine signaling at 36E homolog 0.0037 0.0042 0.0355
Entamoeba histolytica hypothetical protein 0.0049 0.0064 0.0505
Brugia malayi hypothetical protein 0.0037 0.0042 0.0515
Entamoeba histolytica SH2-protein kinase domain containing protein 0.0038 0.0043 0.0337
Trypanosoma brucei isocitrate dehydrogenase, putative 0.0047 0.0062 0.7649
Leishmania major glucose transporter, lmgt3 0.003 0.0028 0.2725
Echinococcus multilocularis tyrosine protein kinase ABL1 0.0086 0.0138 0.0202
Schistosoma mansoni nuclear receptor 0.0021 0.0009 0.0014
Leishmania major 4-coumarate:coa ligase-like protein 0.0027 0.0021 0.2014
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD3 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0019 0.0005 0.0005
Trypanosoma brucei protein kinase, putative 0.0057 0.0081 1
Echinococcus multilocularis retinal guanylyl cyclase 2 0.0049 0.0064 0.0094
Trypanosoma brucei Pseudokinase, putative 0.0049 0.0064 0.7963
Leishmania major kinesin, putative 0.0017 0.0002 0.0235
Schistosoma mansoni tyrosine kinase 0.0086 0.0138 0.0202
Mycobacterium ulcerans ATP-dependent Clp protease proteolytic subunit 0.0091 0.0148 0.0148
Echinococcus granulosus chromobox protein 1 0.0072 0.0111 0.0163
Brugia malayi Nuclear hormone receptor family member nhr-14 0.0044 0.0055 0.0678
Loa Loa (eye worm) TK/FER protein kinase 0.0086 0.0138 0.1696
Brugia malayi conserved hypotetical protein 0.0021 0.0009 0.0114
Trichomonas vaginalis bromodomain-containing protein, putative 0.005 0.0066 0.0712
Loa Loa (eye worm) hypothetical protein 0.0044 0.0055 0.0678
Echinococcus multilocularis muscleblind protein 0.0402 0.0759 0.1117
Trichomonas vaginalis TKL family protein kinase 0.0049 0.0064 0.0692
Mycobacterium ulcerans acyl-CoA synthetase 0.0027 0.0021 0.0021
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.002 0.0007 0.0073
Brugia malayi cytokine inducible SH2-containing protein 5 0.0037 0.0042 0.0515
Toxoplasma gondii LsmAD domain-containing protein 0.0029 0.0026 0.1206
Loa Loa (eye worm) hypothetical protein 0.0049 0.0064 0.0791
Brugia malayi nuclear receptor RXR 0.0023 0.0014 0.0174
Schistosoma mansoni vav2 0.0037 0.0042 0.0061
Trypanosoma cruzi JmjC domain, hydroxylase, putative 0.002 0.0007 0.0839
Loa Loa (eye worm) TK/FER protein kinase 0.0049 0.0064 0.0791
Echinococcus granulosus hypothetical protein 0.0037 0.0042 0.0061
Schistosoma mansoni hypothetical protein 0.008 0.0126 0.0185
Echinococcus multilocularis tyrosine protein kinase shark 0.0086 0.0138 0.0202
Echinococcus multilocularis cadherin EGF LAG seven pass G type receptor 0.008 0.0126 0.0185
Echinococcus granulosus tyrosine kinase 0.0086 0.0138 0.0202
Echinococcus granulosus calpain 0.0017 0.0002 0.0004
Trichomonas vaginalis CMGC family protein kinase 0.0057 0.0081 0.0869
Trypanosoma brucei THT1 - hexose transporter, putative 0.003 0.0028 0.3453
Brugia malayi Protein kinase domain containing protein 0.0049 0.0064 0.0791
Brugia malayi Protein kinase domain containing protein 0.0049 0.0064 0.0791
Wolbachia endosymbiont of Brugia malayi ATP-dependent Clp protease proteolytic subunit 0.0091 0.0148 0.0148
Loa Loa (eye worm) hypothetical protein 0.0276 0.0511 0.6293
Loa Loa (eye worm) hypothetical protein 0.0049 0.0064 0.0791
Loa Loa (eye worm) histone methyltransferase 0.0022 0.0011 0.0139
Echinococcus granulosus retinoic acid receptor rxr beta a 0.0044 0.0055 0.0081
Trypanosoma brucei cysteine peptidase, Clan CA, family C2, putative 0.0017 0.0002 0.0298
Brugia malayi Sex muscle abnormal protein 5 0.0037 0.0042 0.0515
Loa Loa (eye worm) TK/KIN16 protein kinase 0.0049 0.0064 0.0791
Schistosoma mansoni tyrosine kinase 0.0049 0.0064 0.0094
Echinococcus granulosus tyrosine protein kinase csk 0.0049 0.0064 0.0094
Loa Loa (eye worm) cytokine inducible SH2-containing protein 5 0.0037 0.0042 0.0515
Loa Loa (eye worm) jmjC domain-containing protein 0.002 0.0007 0.0083
Leishmania major 4-coumarate:coa ligase-like protein 0.0027 0.0021 0.2014
Plasmodium vivax tyrosine kinase-like protein, putative 0.0049 0.0064 0.0064
Brugia malayi Nuclear hormone receptor E75 0.0021 0.0009 0.0114
Schistosoma mansoni glucose transport protein 0.0097 0.016 0.0236
Brugia malayi Guanylyl cyclase protein 23 0.0049 0.0064 0.0791
Echinococcus granulosus guanine nucleotide exchange factor VAV2 0.0037 0.0042 0.0061
Brugia malayi tailless protein 0.0021 0.0009 0.0114
Trypanosoma brucei antigen, putative 0.0017 0.0002 0.0298
Trichomonas vaginalis TKL family protein kinase 0.0049 0.0064 0.0692
Loa Loa (eye worm) acetyltransferase 0.0169 0.0301 0.3706
Trichomonas vaginalis sugar transporter, putative 0.003 0.0028 0.03
Loa Loa (eye worm) hypothetical protein 0.0037 0.0042 0.0515
Leishmania major glucose transporter/membrane transporter D2, putative 0.003 0.0028 0.2725
Plasmodium falciparum isocitrate dehydrogenase [NADP], mitochondrial 0.0047 0.0062 0.0062
Echinococcus granulosus tyrosine protein phosphatase non receptor type 0.0037 0.0042 0.0061
Trypanosoma cruzi cysteine peptidase, Clan CA, family C2, putative 0.0017 0.0002 0.0298
Entamoeba histolytica protein tyrosine kinase domain-containing protein 0.0049 0.0064 0.0505
Loa Loa (eye worm) TKL/RAF/RAF protein kinase 0.0049 0.0064 0.0791
Loa Loa (eye worm) TK/Met protein kinase 0.0049 0.0064 0.0791
Schistosoma mansoni proto-oncogene tyrosine-protein kinase src 0.0086 0.0138 0.0202
Trypanosoma brucei JmjC domain, hydroxylase, putative 0.002 0.0007 0.0839
Echinococcus granulosus proto oncogene tyrosine protein kinase LCK 0.0086 0.0138 0.0202
Brugia malayi Adenylate and Guanylate cyclase catalytic domain containing protein 0.0049 0.0064 0.0791
Trichomonas vaginalis AGC family protein kinase 0.0049 0.0064 0.0692
Echinococcus multilocularis lysine specific demethylase 6a 0.002 0.0007 0.001
Entamoeba histolytica fatty acid elongase, putative 0.0662 0.1271 1
Schistosoma mansoni retinoid-x-receptor (RXR) 0.0044 0.0055 0.0081
Trichomonas vaginalis TKL family protein kinase 0.0049 0.0064 0.0692
Schistosoma mansoni nuclear receptor nhr-48 0.0021 0.0009 0.0014
Brugia malayi Nuclear hormone receptor family member nhr-1 0.0044 0.0055 0.0678
Onchocerca volvulus 0.0176 0.0315 0.3328
Brugia malayi Protein kinase domain containing protein 0.0049 0.0064 0.0791
Schistosoma mansoni glucose transport protein 0.0097 0.016 0.0236
Echinococcus multilocularis chromobox protein 1 0.0072 0.0111 0.0163
Schistosoma mansoni phd/f-box containing protein 0.002 0.0007 0.001
Chlamydia trachomatis ATP-dependent Clp protease proteolytic subunit 0.0091 0.0148 0.014
Entamoeba histolytica serine/threonine kinase, putative 0.0049 0.0064 0.0505
Brugia malayi Variant SH3 domain containing protein 0.0037 0.0042 0.0515
Trypanosoma cruzi hexose transporter, putative 0.003 0.0028 0.3453
Plasmodium falciparum ataxin-2 like protein, putative 0.0029 0.0026 0.0026
Schistosoma mansoni tyrosine kinase 0.0049 0.0064 0.0094
Schistosoma mansoni tyrosine kinase 0.0049 0.0064 0.0094
Entamoeba histolytica protein kinase, putative 0.0049 0.0064 0.0505
Echinococcus granulosus tyrosine protein kinase Fes:Fps 0.0049 0.0064 0.0094
Brugia malayi Protein kinase domain containing protein 0.0049 0.0064 0.0791
Echinococcus multilocularis histone lysine N methyltransferase MLL3 0.0022 0.0011 0.0017
Loa Loa (eye worm) hypothetical protein 0.0027 0.0021 0.0253
Toxoplasma gondii histone lysine demethylase JMJC1/KDM5D/JARID1D 0.002 0.0007 0.0312
Brugia malayi isocitrate dehydrogenase 0.0047 0.0062 0.076
Brugia malayi hypothetical protein 0.0023 0.0014 0.0174
Brugia malayi Pre-SET motif family protein 0.0428 0.0811 1
Loa Loa (eye worm) TK/DDR protein kinase 0.0049 0.0064 0.0791
Echinococcus multilocularis histone lysine N methyltransferase MLL3 0.0018 0.0004 0.0005
Brugia malayi Nuclear hormone receptor-like 1 0.0044 0.0055 0.0678
Brugia malayi ecdysteroid receptor 0.0044 0.0055 0.0678
Trichomonas vaginalis conserved hypothetical protein 0.0049 0.0064 0.0692
Loa Loa (eye worm) RGC/RGC protein kinase 0.0049 0.0064 0.0791
Entamoeba histolytica protein tyrosine kinase domain-containing protein 0.0049 0.0064 0.0505
Trichomonas vaginalis CAMK family protein kinase 0.0049 0.0064 0.0692
Plasmodium vivax isocitrate dehydrogenase [NADP], mitochondrial, putative 0.0047 0.0062 0.0062
Schistosoma mansoni tyrosine protein kinase fes (fps) (ptk group IV) 0.0049 0.0064 0.0094
Loa Loa (eye worm) hypothetical protein 0.0021 0.0009 0.0114
Brugia malayi Nuclear hormone receptor family member nhr-3 0.0044 0.0055 0.0678
Loa Loa (eye worm) nuclear hormone receptor family member nhr-31 0.0044 0.0055 0.0678
Schistosoma mansoni tyrosine kinase 0.0049 0.0064 0.0094
Echinococcus multilocularis tyrosine protein kinase transmembrane receptor 0.0049 0.0064 0.0094
Entamoeba histolytica protein kinase domain containing protein 0.0049 0.0064 0.0505
Echinococcus granulosus FTZ F1 nuclear receptor protein 0.0044 0.0055 0.0081
Plasmodium falciparum hexose transporter 0.0097 0.016 0.016
Loa Loa (eye worm) hypothetical protein 0.0021 0.0009 0.0114
Brugia malayi SH2 domain containing protein 0.0037 0.0042 0.0515
Echinococcus multilocularis tyrosine protein kinase HCK 0.0049 0.0064 0.0094
Echinococcus granulosus natriuretic peptide receptor 1 0.0049 0.0064 0.0094
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0063 0.0092 0.0135
Toxoplasma gondii STE kinase 0.0049 0.0064 0.296
Echinococcus granulosus tyrosine kinase|tyrosine protein kinase Fyn 0.0086 0.0138 0.0202
Echinococcus granulosus nuclear receptor subfamily 1 group D 0.0023 0.0014 0.0021
Echinococcus multilocularis c src tyrosine kinase 0.0086 0.0138 0.0202
Onchocerca volvulus 0.0074 0.0115 0.115
Schistosoma mansoni calpain (C02 family) 0.0017 0.0002 0.0004
Entamoeba histolytica serine/threonine kinase, putative 0.0049 0.0064 0.0505
Echinococcus multilocularis 0.0037 0.0042 0.0061
Brugia malayi Receptor family ligand binding region containing protein 0.0049 0.0064 0.0791
Echinococcus granulosus mitogen activated protein kinase kinase kinase 0.0049 0.0064 0.0094
Loa Loa (eye worm) TK/FER protein kinase 0.0049 0.0064 0.0791
Loa Loa (eye worm) hypothetical protein 0.0037 0.0042 0.0515
Entamoeba histolytica tyrosine kinase, putative 0.0049 0.0064 0.0505
Treponema pallidum ATP-dependent Clp protease proteolytic subunit 0.0091 0.0148 1
Echinococcus multilocularis survival motor neuron protein 1 0.0276 0.0511 0.0751
Loa Loa (eye worm) hypothetical protein 0.002 0.0007 0.0091
Brugia malayi C-terminal src kinase protein 1 0.0049 0.0064 0.0791
Brugia malayi Protein kinase domain containing protein 0.0049 0.0064 0.0791
Brugia malayi jmjC domain containing protein 0.002 0.0007 0.0083
Schistosoma mansoni survival motor neuron protein 0.0056 0.0079 0.0116
Plasmodium vivax protein kinase, putative 0.0049 0.0064 0.0064
Loa Loa (eye worm) TK protein kinase 0.0049 0.0064 0.0791
Trichomonas vaginalis TKL family protein kinase 0.0049 0.0064 0.0692
Entamoeba histolytica protein tyrosine kinase domain-containing protein 0.0049 0.0064 0.0505
Plasmodium falciparum tyrosine kinase-like protein 0.0049 0.0064 0.0064
Onchocerca volvulus 0.0027 0.0021 0.0123
Loa Loa (eye worm) hypothetical protein 0.0021 0.0009 0.0114
Onchocerca volvulus 0.0049 0.0064 0.0598
Trypanosoma cruzi cysteine peptidase, Clan CA, family C2, putative 0.0017 0.0002 0.0298
Loa Loa (eye worm) hypothetical protein 0.0021 0.0009 0.0114
Brugia malayi chromobox protein homolog 3 0.0041 0.0048 0.0592
Schistosoma mansoni hypothetical protein 0.008 0.0126 0.0185
Loa Loa (eye worm) hypothetical protein 0.0041 0.0048 0.0592
Giardia lamblia Protein 21.1 0.0049 0.0064 0.7344
Entamoeba histolytica protein kinase, putative 0.0049 0.0064 0.0505
Entamoeba histolytica protein kinase domain containing protein 0.0049 0.0064 0.0505
Brugia malayi Protein kinase domain containing protein 0.0049 0.0064 0.0791
Brugia malayi Variant SH3 domain containing protein 0.0037 0.0042 0.0515
Echinococcus granulosus calpain A 0.0061 0.0089 0.013
Schistosoma mansoni peptidase Clp (S14 family) 0.0091 0.0148 0.0217
Loa Loa (eye worm) TK/ACK protein kinase 0.0049 0.0064 0.0791
Onchocerca volvulus 0.0037 0.0042 0.0355
Echinococcus multilocularis basic fibroblast growth factor receptor 1 A 0.0049 0.0064 0.0094
Trichomonas vaginalis TKL family protein kinase 0.0049 0.0064 0.0692
Leishmania major hypothetical protein, conserved 0.0049 0.0064 0.6286
Echinococcus multilocularis Basic leucine zipper (bZIP) transcription 0.0037 0.0042 0.0061
Echinococcus granulosus solute carrier family 2 facilitated glucose 0.0097 0.016 0.0236
Brugia malayi Nuclear hormone receptor-like 1 0.0023 0.0014 0.0174
Trichomonas vaginalis TKL family protein kinase 0.0049 0.0064 0.0692
Brugia malayi SH2 domain containing protein 0.0037 0.0042 0.0515
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0063 0.0092 0.0135
Schistosoma mansoni protein tyrosine phosphatase n11 (shp2) 0.0037 0.0042 0.0061
Echinococcus multilocularis SH2 motif 0.0037 0.0042 0.0061
Trichomonas vaginalis TKL family protein kinase 0.0049 0.0064 0.0692
Entamoeba histolytica fatty acid elongase, putative 0.0662 0.1271 1
Schistosoma mansoni adapter molecule crk 0.0037 0.0042 0.0061
Brugia malayi SH2 domain containing protein 0.0037 0.0042 0.0515
Entamoeba histolytica protein kinase domain containing protein 0.0049 0.0064 0.0505
Trichomonas vaginalis serine/threonine-protein kinase wnk, putative 0.0049 0.0064 0.0692
Loa Loa (eye worm) hypothetical protein 0.0037 0.0042 0.0515
Loa Loa (eye worm) hypothetical protein 0.0037 0.0042 0.0515
Trypanosoma cruzi kinesin, putative 0.0017 0.0002 0.0298
Brugia malayi Immunoglobulin I-set domain containing protein 0.0049 0.0064 0.0791
Entamoeba histolytica protein kinase domain containing protein 0.0049 0.0064 0.0505
Schistosoma mansoni hypothetical protein 0.0901 0.1741 0.2561
Echinococcus multilocularis NADP dependent isocitrate dehydrogenase 0.0047 0.0062 0.0091
Schistosoma mansoni nuclear hormone receptor superfamily protein-related 0.0021 0.0009 0.0014
Schistosoma mansoni tyrosine kinase 0.0049 0.0064 0.0094
Entamoeba histolytica acyl-CoA synthetase, putative 0.0027 0.0021 0.0162
Loa Loa (eye worm) hypothetical protein 0.0021 0.0009 0.0114
Schistosoma mansoni tyrosine kinase 0.0049 0.0064 0.0094
Trichomonas vaginalis TKL family protein kinase 0.0049 0.0064 0.0692
Echinococcus granulosus tyrosine protein kinase Blk 0.0086 0.0138 0.0202
Echinococcus granulosus phd:f box containing protein 0.002 0.0007 0.001
Echinococcus granulosus thyroid hormone receptor alpha 0.0021 0.0009 0.0014
Schistosoma mansoni hypothetical protein 0.0037 0.0042 0.0061
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0026 0.002 0.0214
Schistosoma mansoni tyrosine kinase 0.0049 0.0064 0.0094
Brugia malayi Protein kinase domain containing protein 0.0049 0.0064 0.0791
Trypanosoma cruzi calpain-like cysteine peptidase, putative 0.0017 0.0002 0.0298
Brugia malayi nuclear hormone receptor family member odr-7 0.0021 0.0009 0.0114
Echinococcus multilocularis thyroid hormone receptor alpha 0.0044 0.0055 0.0081
Brugia malayi Protein kinase domain containing protein 0.0086 0.0138 0.1696
Loa Loa (eye worm) TK/FER protein kinase 0.0049 0.0064 0.0791
Schistosoma mansoni chromobox protein 0.0072 0.0111 0.0163
Plasmodium vivax ATP-dependent Clp protease proteolytic subunit, putative 0.0091 0.0148 0.0148
Loa Loa (eye worm) hypothetical protein 0.002 0.0007 0.0091
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD35 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0019 0.0005 0.0005
Entamoeba histolytica protein tyrosine kinase domain-containing protein 0.0049 0.0064 0.0505
Brugia malayi RNA binding protein 0.0066 0.0098 0.1204
Echinococcus multilocularis mitogen activated protein kinase kinase kinase 0.0049 0.0064 0.0094
Schistosoma mansoni tyrosine kinase 0.0049 0.0064 0.0094
Echinococcus granulosus tyrosine protein kinase Lyn 0.0087 0.0139 0.0204
Entamoeba histolytica tyrosine- protein kinase 2, putative 0.0049 0.0064 0.0505
Echinococcus granulosus mitogen activated protein kinase 3 0.0057 0.0081 0.0119
Trichomonas vaginalis conserved hypothetical protein 0.0041 0.0048 0.0518
Trichomonas vaginalis glucose transporter, putative 0.003 0.0028 0.03
Toxoplasma gondii facilitative glucose transporter GT1 0.0097 0.016 0.7387
Schistosoma mansoni GTPase activating protein 0.0037 0.0042 0.0061
Echinococcus multilocularis suppressor of cytokine signaling 6 0.0037 0.0042 0.0061
Loa Loa (eye worm) calpain family protein 1 0.0041 0.0049 0.0601
Entamoeba histolytica tyrosine kinase, putative 0.0049 0.0064 0.0505
Brugia malayi AMP-binding enzyme family protein 0.0027 0.0021 0.0253
Schistosoma mansoni tyrosine kinase 0.0049 0.0064 0.0094
Loa Loa (eye worm) hypothetical protein 0.0091 0.0148 0.182
Schistosoma mansoni chimerin-related rho-gtpase-activating protein 0.0037 0.0042 0.0061
Echinococcus granulosus insulin receptor 0.0049 0.0064 0.0094
Toxoplasma gondii aldehyde dehydrogenase 0.0068 0.0102 0.471
Schistosoma mansoni Tr4/Tr2 (homologue) 0.0044 0.0055 0.0081
Entamoeba histolytica hypothetical protein 0.0037 0.0042 0.0329
Brugia malayi hypothetical protein 0.0086 0.0138 0.1696
Loa Loa (eye worm) hypothetical protein 0.0021 0.0009 0.0114
Entamoeba histolytica protein kinase domain containing protein 0.0049 0.0064 0.0505
Echinococcus multilocularis tyrosine protein kinase Fyn 0.0086 0.0138 0.0202
Echinococcus granulosus nuclear receptor nhr 48 0.0021 0.0009 0.0014
Echinococcus multilocularis tyrosine protein kinase Fyn 0.0086 0.0138 0.0202
Trichomonas vaginalis TKL family protein kinase 0.0049 0.0064 0.0692
Onchocerca volvulus 0.0037 0.0042 0.0355
Brugia malayi nuclear receptor NHR-67 0.0021 0.0009 0.0114
Schistosoma mansoni hypothetical protein 0.0049 0.0064 0.0094
Mycobacterium ulcerans 3-oxoacyl-ACP synthase 0.5097 1 1
Trypanosoma brucei isocitrate dehydrogenase [NADP], mitochondrial precursor, putative 0.0047 0.0062 0.7649
Loa Loa (eye worm) hypothetical protein 0.0021 0.0009 0.0114
Loa Loa (eye worm) sugar transporter 0.0097 0.016 0.1973
Plasmodium vivax JmjC domain containing protein 0.002 0.0007 0.0007
Echinococcus multilocularis tyrosine protein kinase Fps85D 0.0086 0.0138 0.0202
Loa Loa (eye worm) protein-tyrosine phosphatase 0.0037 0.0042 0.0515
Brugia malayi Protein kinase domain containing protein 0.0049 0.0064 0.0791
Schistosoma mansoni nuclear hormone receptor 0.0021 0.0009 0.0014
Toxoplasma gondii ATP-dependent Clp endopeptidase, proteolytic subunit ClpP domain-containing protein 0.0091 0.0148 0.6812
Mycobacterium tuberculosis Probable aldehyde dehydrogenase 0.0068 0.0102 0.0102
Toxoplasma gondii PHD-finger domain-containing protein 0.006 0.0087 0.4031
Toxoplasma gondii isocitrate dehydrogenase 0.0047 0.0062 0.2843
Loa Loa (eye worm) hypothetical protein 0.0176 0.0315 0.388
Schistosoma mansoni suppressor of cytokine signaling 0.0037 0.0042 0.0061
Schistosoma mansoni cpg binding protein 0.0067 0.01 0.0147
Entamoeba histolytica leucine-rich repeat domain-containing protein 0.0049 0.0064 0.0505
Trypanosoma cruzi PAB1-binding protein , putative 0.0029 0.0026 0.3245
Entamoeba histolytica acetyltransferase, GNAT family 0.0046 0.0058 0.0456
Trichomonas vaginalis TKL family protein kinase 0.0049 0.0064 0.0692
Brugia malayi Tensin 0.0037 0.0042 0.0515
Loa Loa (eye worm) hypothetical protein 0.0402 0.0759 0.9358
Echinococcus granulosus NCK adaptor protein 0.0037 0.0042 0.0061
Brugia malayi Furin-like cysteine rich region family protein 0.0049 0.0064 0.0791
Brugia malayi hypothetical protein 0.0021 0.0009 0.0114
Trichomonas vaginalis TKL family protein kinase 0.0049 0.0064 0.0692
Schistosoma mansoni tyrosine kinase 0.0086 0.0138 0.0202
Brugia malayi ecdysone receptor 0.0021 0.0009 0.0114
Echinococcus multilocularis jumonji domain containing protein 0.0084 0.0134 0.0197
Echinococcus multilocularis insulin growth factor 1 receptor beta 0.0049 0.0064 0.0094
Echinococcus granulosus tyrosine protein kinase Srms 0.0086 0.0138 0.0202
Echinococcus multilocularis family C2 unassigned peptidase (C02 family) 0.0061 0.0089 0.013
Schistosoma mansoni tyrosine-protein kinase fps85d 0.0049 0.0064 0.0094
Brugia malayi Variant SH3 domain containing protein 0.0037 0.0042 0.0515
Brugia malayi RNA recognition motif domain containing protein 0.0066 0.0098 0.1204
Echinococcus granulosus mixed lineage leukemia protein mll 0.0018 0.0004 0.0005
Echinococcus granulosus peptidase Clp S14 family 0.006 0.0086 0.0126
Leishmania major protein kinase, putative 0.0049 0.0064 0.6286
Echinococcus granulosus tyrosine protein kinase Fyn 0.0086 0.0138 0.0202
Echinococcus granulosus histone lysine methyltransferase setb 0.0063 0.0092 0.0135
Trypanosoma cruzi mitogen activated protein kinase 2, putative 0.0057 0.0081 1
Schistosoma mansoni protein phosphatase 2C 0.002 0.0007 0.001
Loa Loa (eye worm) hypothetical protein 0.008 0.0126 0.1551
Echinococcus multilocularis activated cdc42 kinase 1 0.0049 0.0064 0.0094
Brugia malayi Pre-SET motif family protein 0.0063 0.0092 0.1129
Giardia lamblia Histone acetyltransferase GCN5 0.0046 0.0058 0.6631
Trichomonas vaginalis TKL family protein kinase 0.0049 0.0064 0.0692
Schistosoma mansoni hypothetical protein 0.0321 0.06 0.0882
Loa Loa (eye worm) hypothetical protein 0.002 0.0007 0.0083
Plasmodium falciparum histone acetyltransferase GCN5 0.0046 0.0058 0.0058
Schistosoma mansoni protein kinase 0.0049 0.0064 0.0094
Echinococcus granulosus activated cdc42 kinase 1 0.0049 0.0064 0.0094
Onchocerca volvulus 0.0049 0.0064 0.0598
Loa Loa (eye worm) calpain 0.0017 0.0002 0.003
Echinococcus multilocularis protein kinase 0.0049 0.0064 0.0094
Trypanosoma cruzi hexose transporter 0.003 0.0028 0.3453
Trichomonas vaginalis TKL family protein kinase 0.0049 0.0064 0.0692
Echinococcus granulosus protein tyrosine kinase 0.0049 0.0064 0.0094
Loa Loa (eye worm) TKL/STKR/TYPE1 protein kinase 0.0049 0.0064 0.0791
Trichomonas vaginalis TKL family protein kinase 0.0049 0.0064 0.0692
Onchocerca volvulus Atrial natriuretic peptide receptor 3 homolog 0.0049 0.0064 0.0598
Onchocerca volvulus 0.0037 0.0042 0.0355
Loa Loa (eye worm) nuclear receptor nhr-7B 0.0021 0.0009 0.0114
Echinococcus multilocularis tyrosine kinase 0.0049 0.0064 0.0094
Onchocerca volvulus 0.0049 0.0064 0.0598
Echinococcus multilocularis FL cytokine receptor 0.0049 0.0064 0.0094
Echinococcus granulosus Nuclear hormone receptor HR96 0.0021 0.0009 0.0014
Loa Loa (eye worm) hypothetical protein 0.002 0.0007 0.0091
Loa Loa (eye worm) TK/FAK protein kinase 0.0049 0.0064 0.0791
Trypanosoma cruzi kinesin, putative 0.0017 0.0002 0.0298
Loa Loa (eye worm) pre-SET domain-containing protein family protein 0.0428 0.0811 1
Entamoeba histolytica ankyrin repeat protein 0.0049 0.0064 0.0505
Trypanosoma cruzi STE/STE11 serine/threonine-protein kinase, putative 0.0049 0.0065 0.8089
Wolbachia endosymbiont of Brugia malayi 3-oxoacyl-ACP synthase 0.5097 1 1
Entamoeba histolytica protein kinase domain containing protein 0.0049 0.0064 0.0505
Onchocerca volvulus Tyrosine kinase receptor Cad96Ca homolog 0.0049 0.0064 0.0598
Echinococcus granulosus signal transduction protein lnk realted 0.0037 0.0042 0.0061
Echinococcus multilocularis ATP dependent Clp protease proteolytic subunit 0.0091 0.0148 0.0217
Trichomonas vaginalis TKL family protein kinase 0.0049 0.0064 0.0692
Schistosoma mansoni serine/threonine RGC 0.0049 0.0064 0.0094
Loa Loa (eye worm) sex muscle abnormal protein 5 0.0037 0.0042 0.0515
Schistosoma mansoni protein kinase 0.0049 0.0064 0.0094
Entamoeba histolytica protein tyrosine kinase domain-containing protein 0.0049 0.0064 0.0505
Plasmodium vivax ATP-dependent Clp protease proteolytic subunit, putative 0.0031 0.003 0.003
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.0017 0.0002 0.0235
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0044 0.0055 0.0678
Brugia malayi Probable ClpP-like protease 0.0091 0.0148 0.182
Echinococcus multilocularis PHD finger protein rhinoceros 0.006 0.0087 0.0129
Schistosoma mansoni hypothetical protein 0.0037 0.0042 0.0061
Mycobacterium leprae PROBABLE ATP-DEPENDENT CLP PROTEASE PROTEOLYTIC SUBUNIT 2 CLPP2 (ENDOPEPTIDASE CLP 2) 0.0091 0.0148 1
Loa Loa (eye worm) nuclear Hormone Receptor family member 0.0044 0.0055 0.0678
Schistosoma mansoni tyrosine-protein kinase zap-70 0.0037 0.0042 0.0061
Echinococcus multilocularis hepatocyte nuclear factor 4 alpha 0.0044 0.0055 0.0081
Entamoeba histolytica receptor protein kinase, putative 0.0049 0.0064 0.0505
Loa Loa (eye worm) SRC-1 0.0086 0.0138 0.1696
Brugia malayi Isocitrate dehydrogenase 0.0047 0.0062 0.076
Echinococcus multilocularis retinal guanylyl cyclase 2 0.0049 0.0064 0.0094
Onchocerca volvulus 0.0049 0.0064 0.0598
Entamoeba histolytica tyrosin kinase, putative 0.0049 0.0064 0.0505
Echinococcus multilocularis tyrosine protein kinase Src64B 0.0086 0.0138 0.0202
Trypanosoma cruzi protein kinase, putative 0.0049 0.0064 0.7963
Mycobacterium ulcerans ATP-dependent Clp protease proteolytic subunit 0.0091 0.0148 0.0148
Brugia malayi Raf kinase 0.0049 0.0064 0.0791
Trichomonas vaginalis TKL family protein kinase 0.0049 0.0064 0.0692
Echinococcus granulosus expressed conserved protein 0.0037 0.0042 0.0061
Plasmodium falciparum ataxin-2 like protein, putative 0.0029 0.0026 0.0026
Giardia lamblia PHD finger protein 15 0.006 0.0087 1
Schistosoma mansoni tar DNA-binding protein 0.0066 0.0098 0.0144
Trichomonas vaginalis sugar transporter, putative 0.003 0.0028 0.03
Brugia malayi nuclear hormone receptor 0.0021 0.0009 0.0114
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0063 0.0092 0.0135
Brugia malayi integrin-linked kinase 0.0049 0.0064 0.0791
Brugia malayi protein-tyrosine kinase 0.0086 0.0138 0.1696
Echinococcus multilocularis SH2 motif 0.0037 0.0042 0.0061
Echinococcus multilocularis guanine nucleotide exchange factor VAV2 0.0037 0.0042 0.0061
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0136 0.0237 0.0348
Schistosoma mansoni tyrosine kinase 0.0049 0.0064 0.0094
Echinococcus multilocularis SH2 motif 0.0037 0.0042 0.0061
Echinococcus multilocularis calpain 0.0017 0.0002 0.0004
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0044 0.0055 0.0678
Echinococcus granulosus 3'partial|retinal guanylyl cyclase 2 0.0049 0.0064 0.0094
Entamoeba histolytica protein kinase domain containing protein 0.0049 0.0064 0.0505
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0044 0.0055 0.0081
Loa Loa (eye worm) TK protein kinase 0.0049 0.0064 0.0791
Brugia malayi Protein-tyrosine phosphatase containing protein 0.0037 0.0042 0.0515
Schistosoma mansoni src-type protein tyrosine kinase-related 0.0049 0.0064 0.0094
Echinococcus multilocularis calpain 5 0.0017 0.0002 0.0004
Brugia malayi Protein kinase domain containing protein 0.0049 0.0064 0.0791
Trichomonas vaginalis TKL family protein kinase 0.0049 0.0064 0.0692
Echinococcus multilocularis histone lysine N methyltransferase SETMAR 0.0063 0.0092 0.0135
Trypanosoma brucei STE/STE11 serine/threonine-protein kinase, putative 0.0049 0.0065 0.8089
Trypanosoma brucei calpain-like cysteine peptidase, putative 0.0017 0.0002 0.0298
Trichomonas vaginalis TKL family protein kinase 0.0049 0.0064 0.0692
Echinococcus multilocularis isocitrate dehydrogenase 2 (NADP+) 0.0047 0.0062 0.0091
Entamoeba histolytica protein kinase, putative 0.0049 0.0064 0.0505
Onchocerca volvulus 0.0049 0.0064 0.0598
Toxoplasma gondii Tyrosine kinase-like (TKL) protein 0.0049 0.0064 0.296
Echinococcus multilocularis jumonji domain containing 1A 0.002 0.0007 0.001
Onchocerca volvulus 0.0037 0.0042 0.0355
Echinococcus multilocularis kinase suppressor of Ras 1 0.0049 0.0064 0.0094
Schistosoma mansoni retinoid-x-receptor (RXR) 0.0023 0.0014 0.0021
Loa Loa (eye worm) DR-78 0.0021 0.0009 0.0114
Loa Loa (eye worm) nuclear hormone receptor family member nhr-49 0.0044 0.0055 0.0678
Loa Loa (eye worm) TK/EGFR protein kinase 0.0049 0.0064 0.0791
Entamoeba histolytica protein kinase, putative 0.0049 0.0064 0.0505
Loa Loa (eye worm) hypothetical protein 0.0021 0.0009 0.0114
Loa Loa (eye worm) TK/FER protein kinase 0.0086 0.0138 0.1696
Loa Loa (eye worm) jmjC domain-containing protein 0.002 0.0007 0.0083
Echinococcus multilocularis Nuclear hormone receptor HR96 0.0021 0.0009 0.0014
Trypanosoma brucei glucose transporter, putative 0.003 0.0028 0.3453
Loa Loa (eye worm) SH2 domain-containing protein 0.0037 0.0042 0.0515
Brugia malayi hypothetical protein 0.0023 0.0014 0.0174
Schistosoma mansoni calpain-7 (C02 family) 0.0017 0.0002 0.0004
Echinococcus granulosus calpain 7 C02 family 0.0017 0.0002 0.0004
Loa Loa (eye worm) hypothetical protein 0.0044 0.0055 0.0678
Trichomonas vaginalis protein kinase atn1, putative 0.0049 0.0064 0.0692
Trypanosoma brucei protein kinase, putative 0.0049 0.0065 0.8089
Brugia malayi Corticotropin releasing factor receptor 2 precursor, putative 0.0253 0.0466 0.5746
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0026 0.002 0.0214
Brugia malayi AMP-binding enzyme family protein 0.0027 0.0021 0.0253
Trichomonas vaginalis TKL family protein kinase 0.0049 0.0064 0.0692
Echinococcus granulosus dnaJ subfamily B 0.0901 0.1741 0.2561
Brugia malayi jmjC domain containing protein 0.002 0.0007 0.0083
Echinococcus granulosus insulin growth factor 1 receptor beta 0.0049 0.0064 0.0094
Brugia malayi MAP kinase sur-1 0.0057 0.0081 0.0993
Schistosoma mansoni aldehyde dehydrogenase 0.0068 0.0102 0.015
Echinococcus multilocularis calpain A 0.0061 0.0089 0.013
Echinococcus multilocularis proto oncogene tyrosine protein kinase LCK 0.0086 0.0138 0.0202
Echinococcus multilocularis peptidase Clp (S14 family) 0.006 0.0086 0.0126
Brugia malayi Muscleblind-like protein 0.0402 0.0759 0.9358
Entamoeba histolytica hypothetical protein 0.0049 0.0064 0.0505
Toxoplasma gondii Tyrosine kinase-like (TKL) protein 0.0049 0.0064 0.296
Trichomonas vaginalis TKL family protein kinase 0.0049 0.0064 0.0692
Loa Loa (eye worm) TK/FER protein kinase 0.0086 0.0138 0.1696
Trypanosoma cruzi JmjC domain, hydroxylase, putative 0.002 0.0007 0.0839
Trichomonas vaginalis TKL family protein kinase 0.0049 0.0064 0.0692
Echinococcus multilocularis FTZ F1 nuclear receptor protein 0.0044 0.0055 0.0081
Brugia malayi Protein kinase domain containing protein 0.0049 0.0064 0.0791
Toxoplasma gondii protein kinase 0.0049 0.0064 0.296
Loa Loa (eye worm) RNA binding protein 0.0066 0.0098 0.1204
Plasmodium falciparum protein kinase, putative 0.0049 0.0064 0.0064
Loa Loa (eye worm) hypothetical protein 0.0037 0.0042 0.0515
Loa Loa (eye worm) hypothetical protein 0.0044 0.0055 0.0678
Brugia malayi Protein kinase domain containing protein 0.0049 0.0064 0.0791
Loa Loa (eye worm) TKL/MLK/TAK1 protein kinase 0.0049 0.0064 0.0791
Leishmania major glucose transporter, lmgt2 0.003 0.0028 0.2725
Brugia malayi Protein kinase domain containing protein 0.0086 0.0138 0.1696
Plasmodium vivax histone acetyltransferase GCN5, putative 0.005 0.0066 0.0066
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0026 0.002 0.0214
Schistosoma mansoni thyroid hormone receptor 0.0044 0.0055 0.0081
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0044 0.0055 0.0678
Echinococcus granulosus tyrosine protein kinase Btk29A 0.0086 0.0138 0.0202
Schistosoma mansoni tyrosine kinase 0.0086 0.0138 0.0202
Brugia malayi SH2 domain containing protein 0.0037 0.0042 0.0515
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.0017 0.0002 0.0235
Brugia malayi latrophilin 2 splice variant baaae 0.0173 0.0309 0.3805
Entamoeba histolytica serine/threonine kinase, putative 0.0049 0.0064 0.0505
Schistosoma mansoni RAR-like nuclear receptor 0.0044 0.0055 0.0081
Entamoeba histolytica protein kinase domain containing protein 0.0049 0.0064 0.0505
Giardia lamblia Kinase, NEK 0.0049 0.0064 0.7344
Echinococcus multilocularis tyrosine protein kinase Fyn 0.0086 0.0138 0.0202
Trichomonas vaginalis TKL family protein kinase 0.0049 0.0064 0.0692
Plasmodium falciparum ATP-dependent Clp protease proteolytic subunit 0.0031 0.003 0.003
Loa Loa (eye worm) hypothetical protein 0.0049 0.0064 0.0791
Loa Loa (eye worm) TK protein kinase 0.0049 0.0064 0.0791
Plasmodium falciparum tyrosine kinase-like protein 0.0049 0.0064 0.0064
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0026 0.002 0.0214
Echinococcus granulosus geminin 0.0321 0.06 0.0882
Trichomonas vaginalis TKL family protein kinase 0.0049 0.0064 0.0692
Schistosoma mansoni FTZ-F1 nuclear receptor-like protein 0.0044 0.0055 0.0081
Echinococcus multilocularis JmjC domain containing protein 4 0.002 0.0007 0.001
Schistosoma mansoni jumonji/arid domain-containing protein 0.0077 0.012 0.0176
Schistosoma mansoni tensin 0.0037 0.0042 0.0061
Trichomonas vaginalis conserved hypothetical protein 0.0049 0.0064 0.0692
Schistosoma mansoni jumonji/arid domain-containing protein 0.0077 0.012 0.0176
Echinococcus granulosus PHD finger protein rhinoceros 0.006 0.0087 0.0129
Echinococcus granulosus epidermal growth factor receptor 0.0049 0.0064 0.0094
Onchocerca volvulus 0.0086 0.0138 0.1398
Entamoeba histolytica tyrosin kinase, putative 0.0049 0.0064 0.0505
Echinococcus multilocularis gcn5proteinral control of amino acid synthesis 0.0169 0.0301 0.0442
Brugia malayi Protein kinase domain containing protein 0.0049 0.0064 0.0791
Mycobacterium ulcerans acyl-CoA synthetase 0.0027 0.0021 0.0021
Brugia malayi Protein kinase domain containing protein 0.0086 0.0138 0.1696
Trichomonas vaginalis conserved hypothetical protein 0.0029 0.0025 0.0267
Echinococcus multilocularis suppressor of cytokine signaling 7 0.0037 0.0042 0.0061
Trypanosoma cruzi cysteine peptidase, Clan CA, family C2, putative 0.0017 0.0002 0.0298
Echinococcus multilocularis dual specificity testis specific protein kinase 0.0049 0.0065 0.0096
Giardia lamblia Kinase, CMGC MAPK 0.0057 0.0081 0.9222
Loa Loa (eye worm) hypothetical protein 0.0049 0.0064 0.0791
Loa Loa (eye worm) TK/ROR protein kinase 0.0049 0.0064 0.0791
Toxoplasma gondii PHD-finger domain-containing protein 0.002 0.0007 0.0334
Entamoeba histolytica protein kinase with ankyrin repeats, putative 0.0049 0.0064 0.0505
Brugia malayi jmjC domain containing protein 0.002 0.0007 0.0083
Entamoeba histolytica tyrosine kinase, putative 0.0049 0.0064 0.0505
Schistosoma mansoni family C2 unassigned peptidase (C02 family) 0.0058 0.0083 0.0122
Brugia malayi F/Y-rich N-terminus family protein 0.0041 0.005 0.0613
Echinococcus granulosus c src tyrosine kinase 0.0086 0.0138 0.0202
Brugia malayi AF-10 protein 0.002 0.0007 0.0089
Mycobacterium ulcerans long-chain-fatty-acid--CoA ligase 0.0027 0.0021 0.0021
Loa Loa (eye worm) hypothetical protein 0.0023 0.0014 0.0177
Onchocerca volvulus Protein ultraspiracle homolog 0.0044 0.0055 0.0499
Schistosoma mansoni nuclear hormone receptor 0.0021 0.0009 0.0014
Entamoeba histolytica hypothetical protein 0.0037 0.0042 0.0329
Loa Loa (eye worm) jmjC domain-containing protein 0.0125 0.0214 0.2639
Entamoeba histolytica tyrosine kinase, putative 0.0049 0.0064 0.0505
Brugia malayi Heterochromatin protein 1 0.0072 0.0111 0.1363
Echinococcus multilocularis tyrosine protein kinase lyn lyn a protein tyrosine kinase lymphocyte specific protein tyrosine kinase 0.0086 0.0138 0.0202
Trichomonas vaginalis TKL family protein kinase 0.0049 0.0064 0.0692
Brugia malayi nuclear hormone receptor family member nhr-6 0.0021 0.0009 0.0114
Onchocerca volvulus Suppressor of cytokine signaling 7 homolog 0.0037 0.0042 0.0355
Entamoeba histolytica calpain large subunit domain III containing protein 0.0017 0.0002 0.0019
Echinococcus granulosus raf serine:threonine protein kinase 0.0049 0.0064 0.0094
Loa Loa (eye worm) TK/KIN6 protein kinase 0.0049 0.0064 0.0791
Schistosoma mansoni signal transduction protein lnk-related 0.0037 0.0042 0.0061
Loa Loa (eye worm) hypothetical protein 0.0049 0.0064 0.0791
Trypanosoma brucei mitogen activated protein kinase 4, putative 0.0057 0.0081 1
Schistosoma mansoni tyrosine kinase 0.0049 0.0064 0.0094
Schistosoma mansoni hypothetical protein 0.0321 0.06 0.0882
Echinococcus granulosus Nuclear hormone receptor HR96 0.0021 0.0009 0.0014
Trichomonas vaginalis conserved hypothetical protein 0.0049 0.0064 0.0692
Trichomonas vaginalis TKL family protein kinase 0.0049 0.0064 0.0692
Entamoeba histolytica protein kinase, putative 0.0049 0.0064 0.0505
Entamoeba histolytica protein kinase domain containing protein 0.0049 0.0064 0.0505
Schistosoma mansoni family C2 unassigned peptidase (C02 family) 0.0061 0.0089 0.013
Echinococcus multilocularis fibroblast growth factor receptor 4 0.0049 0.0064 0.0094
Trypanosoma cruzi protein kinase, putative 0.0049 0.0064 0.7963
Brugia malayi Tyrosine-protein kinase abl-1 0.0086 0.0138 0.1696
Echinococcus granulosus survival motor neuron protein 1 0.0276 0.0511 0.0751
Schistosoma mansoni phosphatidylserine receptor 0.002 0.0007 0.001
Brugia malayi Protein kinase domain containing protein 0.0049 0.0064 0.0791
Loa Loa (eye worm) hypothetical protein 0.0021 0.0009 0.0114
Loa Loa (eye worm) RGC/RGC protein kinase 0.0049 0.0064 0.0791
Echinococcus granulosus basic fibroblast growth factor receptor 1 A 0.0049 0.0064 0.0094
Echinococcus granulosus jumonji domain containing protein 0.0084 0.0134 0.0197
Loa Loa (eye worm) hypothetical protein 0.002 0.0007 0.0083
Echinococcus granulosus family C2 unassigned peptidase C02 family 0.0061 0.0089 0.013
Schistosoma mansoni nuclear hormone receptor 0.0044 0.0055 0.0081
Echinococcus multilocularis tyrosine protein kinase Abl 0.0086 0.0138 0.0202
Echinococcus granulosus tyrosine protein kinase Btk29A 0.0049 0.0064 0.0094
Trichomonas vaginalis TKL family protein kinase 0.0049 0.0064 0.0692
Loa Loa (eye worm) hypothetical protein 0.0049 0.0064 0.0791
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0038 0.0043 0.0063
Entamoeba histolytica protein kinase domain containing protein 0.0049 0.0064 0.0505
Onchocerca volvulus 0.0086 0.0138 0.1398
Entamoeba histolytica protein tyrosine kinase domain-containing protein 0.0049 0.0064 0.0505
Loa Loa (eye worm) RGC/RGC protein kinase 0.0049 0.0064 0.0791
Trichomonas vaginalis TKL family protein kinase 0.0049 0.0064 0.0692
Echinococcus multilocularis NADP dependent isocitrate dehydrogenase 0.0047 0.0062 0.0091
Trichomonas vaginalis TKL family protein kinase 0.0049 0.0064 0.0692
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0044 0.0055 0.0081
Trypanosoma brucei calpain-like protein, putative 0.0017 0.0002 0.0298
Echinococcus multilocularis tyrosine protein kinase Src42A 0.0086 0.0138 0.0202
Echinococcus multilocularis tyrosine protein kinase Src42A 0.0037 0.0042 0.0061
Brugia malayi hypothetical protein 0.0049 0.0064 0.0791
Schistosoma mansoni tyrosine kinase 0.0049 0.0064 0.0094
Entamoeba histolytica protein kinase, putative 0.0049 0.0064 0.0505
Onchocerca volvulus 0.0487 0.0928 1
Entamoeba histolytica protein tyrosine kinase domain-containing protein 0.0049 0.0064 0.0505
Entamoeba histolytica tyrosine kinase, putative 0.0049 0.0064 0.0505
Echinococcus granulosus atrial natriuretic peptide receptor 1 0.0049 0.0064 0.0094
Echinococcus granulosus microtubule associated protein 2 0.3471 0.6799 1
Loa Loa (eye worm) TK/INSR protein kinase 0.0049 0.0064 0.0791
Entamoeba histolytica acyl-coA synthetase, putative 0.0027 0.0021 0.0162
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0026 0.002 0.0214
Schistosoma mansoni serine/threonine protein kinase 0.0049 0.0064 0.0094
Loa Loa (eye worm) hypothetical protein 0.0104 0.0172 0.2125
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0026 0.002 0.0214
Echinococcus multilocularis heat shock protein 70 0.0049 0.0064 0.0094
Loa Loa (eye worm) hypothetical protein 0.0063 0.0092 0.1129
Loa Loa (eye worm) TKL/MLK/HH498 protein kinase 0.0049 0.0064 0.0791
Entamoeba histolytica tyrosine kinase, putative 0.0049 0.0064 0.0505
Loa Loa (eye worm) hypothetical protein 0.0044 0.0055 0.0678
Onchocerca volvulus Heterochromatin protein 1 homolog 0.0044 0.0054 0.0489
Loa Loa (eye worm) protein kinase domain-containing protein 0.0049 0.0064 0.0791
Brugia malayi proto-oncogene tyrosine-protein kinase FER 0.0049 0.0064 0.0791
Schistosoma mansoni gcn5proteinral control of amino-acid synthesis 5-like 2 gcnl2 0.0169 0.0301 0.0442
Loa Loa (eye worm) hypothetical protein 0.0049 0.0064 0.0791
Brugia malayi Protein kinase domain containing protein 0.0049 0.0064 0.0791
Entamoeba histolytica hypothetical protein 0.0049 0.0064 0.0505
Plasmodium vivax hexose transporter 0.0097 0.016 0.016
Loa Loa (eye worm) hypothetical protein 0.0044 0.0055 0.0678
Loa Loa (eye worm) TK/FER protein kinase 0.0049 0.0064 0.0791
Entamoeba histolytica hypothetical protein 0.0049 0.0064 0.0505
Loa Loa (eye worm) CMGC/MAPK/ERK1 protein kinase 0.0057 0.0081 0.0993
Echinococcus granulosus activin receptor type 0.0049 0.0065 0.0096
Brugia malayi Nuclear hormone receptor family member nhr-49 0.0044 0.0055 0.0678
Echinococcus multilocularis natriuretic peptide receptor 1 0.0049 0.0064 0.0094
Brugia malayi nuclear receptor RXR 0.0021 0.0009 0.0114
Echinococcus granulosus retinal guanylyl cyclase 2 0.0049 0.0064 0.0094
Entamoeba histolytica protein kinase domain containing protein 0.0049 0.0064 0.0505
Toxoplasma gondii histone lysine acetyltransferase GCN5-A 0.005 0.0066 0.3049
Echinococcus granulosus Basic leucine zipper bZIP transcription 0.0037 0.0042 0.0061
Trichomonas vaginalis conserved hypothetical protein 0.0029 0.0025 0.0267
Entamoeba histolytica fatty acid elongase, putative 0.0662 0.1271 1
Onchocerca volvulus 0.0049 0.0064 0.0598
Echinococcus granulosus epidermal growth factor receptor 0.0049 0.0064 0.0094
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0044 0.0055 0.0081
Entamoeba histolytica protein tyrosine kinase domain-containing protein 0.0049 0.0064 0.0505
Loa Loa (eye worm) hypothetical protein 0.0058 0.0083 0.102
Leishmania major isocitrate dehydrogenase [NADP], mitochondrial precursor, putative 0.0047 0.0062 0.6038
Trypanosoma cruzi hexose transporter, putative 0.0017 0.0001 0.0106
Trichomonas vaginalis TKL family protein kinase 0.0049 0.0064 0.0692
Loa Loa (eye worm) hypothetical protein 0.0037 0.0042 0.0515
Trichomonas vaginalis conserved hypothetical protein 0.0049 0.0064 0.0692
Trichomonas vaginalis set domain proteins, putative 0.0487 0.0928 1
Schistosoma mansoni protein kinase 0.0049 0.0064 0.0094
Entamoeba histolytica protein kinase domain containing protein 0.0049 0.0064 0.0505
Entamoeba histolytica SH2-protein kinase domain containing protein 0.0086 0.0138 0.1083
Mycobacterium ulcerans fatty-acid-CoA ligase 0.0027 0.0021 0.0021
Echinococcus multilocularis protein tyrosine kinase 0.0049 0.0064 0.0094
Loa Loa (eye worm) RGC/RGC protein kinase 0.0049 0.0064 0.0791
Echinococcus multilocularis transfer RNA-Thr 0.0049 0.0064 0.0094
Toxoplasma gondii hypothetical protein 0.0031 0.003 0.139
Leishmania major calpain, putative,cysteine peptidase, Clan CA, family C2, putative 0.0017 0.0002 0.0235
Toxoplasma gondii PHD-finger domain-containing protein 0.006 0.0087 0.4031
Trypanosoma brucei glucose transporter, putative 0.003 0.0028 0.3453
Schistosoma mansoni protein kinase 0.0049 0.0064 0.0094
Echinococcus granulosus tyrosine protein kinase transmembrane receptor 0.0049 0.0064 0.0094
Schistosoma mansoni hypothetical protein 0.0037 0.0042 0.0061
Trichomonas vaginalis TKL family protein kinase 0.0049 0.0064 0.0692
Echinococcus multilocularis mitogen activated protein kinase kinase kinase 0.0049 0.0064 0.0094
Echinococcus granulosus growth factor receptor bound protein 2 0.0037 0.0042 0.0061
Plasmodium vivax ataxin-2 like protein, putative 0.0029 0.0026 0.0026
Brugia malayi TAR-binding protein 0.0066 0.0098 0.1204
Trypanosoma brucei glucose transporter, putative 0.003 0.0028 0.3453
Schistosoma mansoni tyrosine-protein kinase fps85d 0.0049 0.0064 0.0094
Trichomonas vaginalis TKL family protein kinase 0.0049 0.0064 0.0692
Plasmodium falciparum protein kinase, putative 0.0049 0.0064 0.0064
Trichomonas vaginalis TKL family protein kinase 0.0049 0.0064 0.0692
Schistosoma mansoni histone-lysine n-methyltransferase suv9 0.0074 0.0115 0.0169
Loa Loa (eye worm) TKL/RAF/KSR protein kinase 0.0049 0.0064 0.0791
Schistosoma mansoni serine/threonine protein kinase 0.0049 0.0064 0.0094
Plasmodium vivax hypothetical protein, conserved 0.0024 0.0015 0.0015
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0021 0.0009 0.0014
Brugia malayi hypothetical protein 0.0037 0.0042 0.0515
Schistosoma mansoni tar DNA-binding protein 0.0066 0.0098 0.0144
Echinococcus multilocularis insulin receptor 0.0049 0.0064 0.0094
Schistosoma mansoni proto-oncogene tyrosine-protein kinase src 0.0049 0.0064 0.0094
Echinococcus granulosus tyrosine protein kinase Fyn 0.0086 0.0138 0.0202
Brugia malayi calcium-independent alpha-latrotoxin receptor 2, putative 0.008 0.0126 0.1551
Trypanosoma brucei calpain-like protein, putative 0.0017 0.0002 0.0298
Schistosoma mansoni hypothetical protein 0.0097 0.016 0.0236
Brugia malayi Protein kinase domain containing protein 0.0049 0.0064 0.0791
Echinococcus granulosus ephrin type A receptor 4 A 0.0049 0.0064 0.0094
Echinococcus granulosus tyrosine protein kinase csk 0.0049 0.0064 0.0094
Loa Loa (eye worm) nuclear hormone receptor-like 1 0.0023 0.0014 0.0174
Brugia malayi SH2 domain containing protein 0.0037 0.0042 0.0515
Echinococcus granulosus tyrosine protein kinase Fps85D 0.0086 0.0138 0.0202
Entamoeba histolytica protein kinase domain containing protein 0.0049 0.0064 0.0505
Trichomonas vaginalis TKL family protein kinase 0.0049 0.0064 0.0692
Mycobacterium ulcerans fatty-acid-CoA ligase 0.002 0.0007 0.0007
Loa Loa (eye worm) hypothetical protein 0.0037 0.0042 0.0515
Brugia malayi Immunoglobulin I-set domain containing protein 0.0049 0.0064 0.0791
Schistosoma mansoni tensin 0.0037 0.0042 0.0061
Trypanosoma brucei PHD-zinc-finger like domain containing protein, putative 0.002 0.0007 0.09
Echinococcus multilocularis muscleblind protein 1 0.0402 0.0759 0.1117
Echinococcus multilocularis tyrosine protein kinase pr2 0.0049 0.0064 0.0094
Loa Loa (eye worm) hypothetical protein 0.002 0.0007 0.0091
Echinococcus granulosus 5'partial|histone lysine N methyltransferase SETDB2 0.0059 0.0084 0.0124
Onchocerca volvulus Alhambra homolog 0.006 0.0087 0.0851
Schistosoma mansoni hypothetical protein 0.002 0.0007 0.0011
Schistosoma mansoni tyrosine kinase 0.0086 0.0138 0.0202
Echinococcus multilocularis peregrin 0.0065 0.0096 0.0141
Echinococcus granulosus tyrosine protein kinase ABL1 0.0086 0.0138 0.0202
Echinococcus multilocularis geminin 0.0321 0.06 0.0882
Loa Loa (eye worm) hypothetical protein 0.0058 0.0083 0.102
Brugia malayi jmjC domain containing protein 0.0077 0.012 0.1473
Entamoeba histolytica acyl-CoA synthetase, putative 0.0027 0.0021 0.0162
Trypanosoma cruzi mitogen activated protein kinase 4, putative 0.0057 0.0081 1
Trichomonas vaginalis TKL family protein kinase 0.0049 0.0064 0.0692
Trichomonas vaginalis chromobox protein, putative 0.0072 0.0111 0.1192
Loa Loa (eye worm) calpain 5 0.0017 0.0002 0.003
Trichomonas vaginalis conserved hypothetical protein 0.0049 0.0064 0.0692
Echinococcus multilocularis microtubule associated protein 2 0.3471 0.6799 1
Entamoeba histolytica protein kinase, putative 0.0049 0.0064 0.0505
Echinococcus multilocularis protein KINase family member (kin 25) 0.0049 0.0064 0.0094
Schistosoma mansoni protein kinase 0.0049 0.0064 0.0094
Brugia malayi RhoGAP domain containing protein 0.0037 0.0042 0.0515
Trypanosoma cruzi isocitrate dehydrogenase, putative 0.0047 0.0062 0.7649
Echinococcus multilocularis epidermal growth factor receptor 0.0049 0.0064 0.0094
Entamoeba histolytica protein kinase domain containing protein 0.0049 0.0064 0.0505
Brugia malayi Nuclear hormone receptor family member nhr-40 0.0044 0.0055 0.0678
Echinococcus multilocularis General substrate transporter 0.0084 0.0133 0.0196
Echinococcus multilocularis calpain 7 (C02 family) 0.0017 0.0002 0.0004
Leishmania major mitogen activated protein kinase 4, putative;with=GeneDB:LmxM19.1440 0.0057 0.0081 0.7893
Echinococcus multilocularis solute carrier family 2 facilitated glucose 0.0097 0.016 0.0236
Entamoeba histolytica protein kinase, putative 0.0049 0.0064 0.0505
Echinococcus granulosus tyrosine protein kinase transmembrane receptor 0.0049 0.0064 0.0094
Echinococcus granulosus Jumonji AT rich interactive domain 1B 0.0023 0.0014 0.002
Echinococcus granulosus tyrosine kinase 0.0086 0.0138 0.0202
Echinococcus granulosus ATP dependent Clp protease proteolytic subunit 0.0091 0.0148 0.0217
Echinococcus multilocularis tyrosine protein kinase csk 0.0049 0.0064 0.0094
Schistosoma mansoni protein kinase 0.0049 0.0065 0.0096
Brugia malayi calpain family protein 1 0.0058 0.0083 0.102
Entamoeba histolytica protein kinase, putative 0.0038 0.0043 0.0337
Schistosoma mansoni SH2A 0.0037 0.0042 0.0061
Loa Loa (eye worm) hypothetical protein 0.0041 0.0049 0.0601
Schistosoma mansoni cpg binding protein 0.0067 0.01 0.0147
Giardia lamblia Kinase, NEK 0.0049 0.0064 0.7344
Echinococcus granulosus aldehyde dehydrogenase mitochondrial 0.0068 0.0102 0.015
Brugia malayi SRC-1 0.0086 0.0138 0.1696
Entamoeba histolytica receptor protein kinase, putative 0.0049 0.0064 0.0505
Trichomonas vaginalis TKL family protein kinase 0.0049 0.0064 0.0692
Trypanosoma brucei calpain-like protein, putative 0.0017 0.0002 0.0298
Plasmodium falciparum ATP-dependent Clp protease proteolytic subunit 0.0091 0.0148 0.0148
Brugia malayi AMP-binding enzyme family protein 0.0027 0.0021 0.0253
Brugia malayi Tyrosine-protein kinase F09A5.2 in chromosome X, putative 0.0049 0.0064 0.0791
Schistosoma mansoni proto-oncogene tyrosine-protein kinase abl1 0.0037 0.0042 0.0061
Entamoeba histolytica serine/threonine kinase, putative 0.0049 0.0064 0.0505
Echinococcus multilocularis nuclear receptor nhr 48 0.0021 0.0009 0.0014
Brugia malayi Steroid receptor seven-up type 2 0.0044 0.0055 0.0678
Mycobacterium tuberculosis 3-oxoacyl-[acyl-carrier-protein] synthase III FabH (beta-ketoacyl-ACP synthase III) (KAS III) 0.5097 1 1
Schistosoma mansoni protein kinase 0.0049 0.0064 0.0094
Loa Loa (eye worm) TK protein kinase 0.0049 0.0064 0.0791
Trichomonas vaginalis TKL family protein kinase 0.0049 0.0064 0.0692
Brugia malayi nuclear receptor subfamily 1, group D, member 1, putative 0.0021 0.0009 0.0114
Entamoeba histolytica protein kinase domain containing protein 0.0049 0.0064 0.0505
Brugia malayi calpain 7 0.0017 0.0002 0.003
Schistosoma mansoni tyrosine kinase 0.0049 0.0064 0.0094
Trichomonas vaginalis CMGC family protein kinase 0.0057 0.0081 0.0869
Echinococcus granulosus solute carrier family 2 facilitated glucose 0.0097 0.016 0.0236
Entamoeba histolytica SH2 domain containing protein 0.0037 0.0042 0.0329
Loa Loa (eye worm) hypothetical protein 0.0021 0.0009 0.0114
Schistosoma mansoni chromobox protein 0.0072 0.0111 0.0163
Echinococcus multilocularis isocitrate dehydrogenase 0.0047 0.0062 0.0091
Loa Loa (eye worm) STAT protein 0.0037 0.0042 0.0515
Entamoeba histolytica protein kinase domain containing protein 0.0049 0.0064 0.0505
Echinococcus granulosus tyrosine protein kinase Src64B 0.0086 0.0138 0.0202
Loa Loa (eye worm) hypothetical protein 0.0049 0.0064 0.0791
Schistosoma mansoni hypothetical protein 0.0056 0.0079 0.0116
Schistosoma mansoni tyrosine kinase 0.0049 0.0064 0.0094
Schistosoma mansoni tar DNA-binding protein 0.0066 0.0098 0.0144
Mycobacterium ulcerans long-chain-fatty-acid-CoA ligase 0.0027 0.0021 0.0021
Loa Loa (eye worm) SH2 domain-containing protein 0.0037 0.0042 0.0515
Entamoeba histolytica tyrosin kinase, putative 0.0049 0.0064 0.0505
Brugia malayi Protein kinase domain containing protein 0.0049 0.0064 0.0791
Loa Loa (eye worm) TK/FER protein kinase 0.0049 0.0064 0.0791
Echinococcus multilocularis integrin linked protein kinase 0.0049 0.0064 0.0094
Entamoeba histolytica protein kinase, putative 0.0049 0.0064 0.0505
Entamoeba histolytica protein kinase domain containing protein 0.0049 0.0064 0.0505
Echinococcus granulosus SH2 motif 0.0037 0.0042 0.0061
Entamoeba histolytica tyrosin kinase, putative 0.0049 0.0064 0.0505
Leishmania major aldehyde dehydrogenase, mitochondrial precursor 0.0068 0.0102 1
Schistosoma mansoni nuclear hormone receptor nor-1/nor-2 0.0044 0.0055 0.0081
Trichomonas vaginalis conserved hypothetical protein 0.0049 0.0064 0.0692
Echinococcus multilocularis tyrosine protein kinase transmembrane receptor 0.0049 0.0064 0.0094
Schistosoma mansoni tensin-related 0.0037 0.0042 0.0061
Trichomonas vaginalis CMGC family protein kinase 0.0057 0.0081 0.0869
Entamoeba histolytica cysteine surface protein, putative 0.0049 0.0064 0.0505
Echinococcus granulosus solute carrier family 2 facilitated glucose 0.0097 0.016 0.0236
Trypanosoma brucei glucose transporter, putative 0.003 0.0028 0.3453
Brugia malayi Protein kinase domain containing protein 0.0049 0.0064 0.0791
Entamoeba histolytica tyrosine kinase, putative 0.0049 0.0064 0.0505
Leishmania major hypothetical protein, conserved 0.0029 0.0026 0.2561
Schistosoma mansoni zinc finger protein 0.0021 0.0009 0.0014
Echinococcus multilocularis activin receptor type 0.0049 0.0065 0.0096
Echinococcus granulosus suppressor of cytokine signaling 6 0.0037 0.0042 0.0061
Brugia malayi Protein kinase domain containing protein 0.0049 0.0064 0.0791
Echinococcus granulosus tyrosine protein kinase Src42A 0.0086 0.0138 0.0202
Loa Loa (eye worm) hypothetical protein 0.0044 0.0055 0.0678
Entamoeba histolytica tyrosine kinase, putative 0.0049 0.0064 0.0505
Trypanosoma cruzi calpain-like cysteine peptidase, putative 0.0017 0.0002 0.0298
Echinococcus granulosus tyrosine kinase 0.0049 0.0064 0.0094
Onchocerca volvulus Tyrosine kinase homolog 0.0049 0.0064 0.0598
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD2 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0027 0.0021 0.0021
Leishmania major hypothetical protein, conserved 0.002 0.0007 0.0663
Trypanosoma cruzi PAB1-binding protein , putative 0.0029 0.0026 0.3245
Brugia malayi Calcitonin receptor-like protein seb-1 0.0253 0.0466 0.5746
Schistosoma mansoni tar DNA-binding protein 0.0066 0.0098 0.0144
Trichomonas vaginalis conserved hypothetical protein 0.003 0.0028 0.03
Brugia malayi Nuclear hormone receptor-like 1 0.0023 0.0014 0.0174
Plasmodium vivax hypothetical protein, conserved 0.006 0.0087 0.0087
Entamoeba histolytica protein kinase domain containing protein 0.0049 0.0064 0.0505
Loa Loa (eye worm) TK/RYK protein kinase 0.0049 0.0064 0.0791
Schistosoma mansoni tyrosine kinase 0.0049 0.0064 0.0094
Echinococcus multilocularis histone lysine methyltransferase setb histone lysine methyltransferase eggless 0.0063 0.0092 0.0135
Trichomonas vaginalis TKL family protein kinase 0.0049 0.0064 0.0692
Echinococcus granulosus COUP TF:Svp nuclear hormone receptor 0.0044 0.0055 0.0081
Trichomonas vaginalis TK family protein kinase 0.0049 0.0064 0.0692
Trypanosoma cruzi calpain-like cysteine peptidase, putative 0.0017 0.0002 0.0298
Brugia malayi Iron-sulfur cluster assembly accessory protein 0.0056 0.0079 0.0973
Echinococcus multilocularis atrial natriuretic peptide receptor 1 0.0049 0.0064 0.0094
Brugia malayi Probable tyrosine-protein kinase kin-31 0.0049 0.0064 0.0791
Brugia malayi nuclear hormone receptor 0.0044 0.0055 0.0678
Echinococcus granulosus peregrin 0.0065 0.0096 0.0141
Loa Loa (eye worm) nuclear hormone receptor family member nhr-14 0.0044 0.0055 0.0678
Trypanosoma brucei glucose transporter 1E 0.003 0.0028 0.3453
Echinococcus multilocularis tyrosine protein kinase Fyn 0.0086 0.0138 0.0202
Onchocerca volvulus 0.0041 0.0049 0.043
Trypanosoma brucei glucose transporter, putative 0.003 0.0028 0.3453
Brugia malayi SH2 domain containing protein 0.0086 0.0138 0.1696
Schistosoma mansoni tyrosine kinase 0.0049 0.0064 0.0094
Entamoeba histolytica ankyrin repeat protein 0.0049 0.0064 0.0505
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0044 0.0055 0.0678
Trichomonas vaginalis TKL family protein kinase 0.0049 0.0064 0.0692
Echinococcus multilocularis SH2 domain containing adapter protein F 0.0037 0.0042 0.0061
Loa Loa (eye worm) TK/FER protein kinase 0.0049 0.0064 0.0791
Onchocerca volvulus 0.0086 0.0138 0.1398
Schistosoma mansoni Mername-AA248 (C02 family) 0.0017 0.0002 0.0004
Trichomonas vaginalis TKL family protein kinase 0.0049 0.0064 0.0692
Loa Loa (eye worm) hypothetical protein 0.0253 0.0466 0.5746
Schistosoma mansoni protein kinase 0.0049 0.0064 0.0094
Loa Loa (eye worm) TK/FER protein kinase 0.0086 0.0138 0.1696
Plasmodium vivax calpain, putative 0.0017 0.0002 0.0002
Echinococcus granulosus fibroblast growth factor receptor 4 0.0049 0.0064 0.0094
Schistosoma mansoni nck2/grb4 0.0037 0.0042 0.0061
Loa Loa (eye worm) TK protein kinase 0.0049 0.0064 0.0791
Loa Loa (eye worm) hypothetical protein 0.0037 0.0042 0.0515
Loa Loa (eye worm) hypothetical protein 0.0044 0.0055 0.0678
Schistosoma mansoni ephrin receptor 0.0049 0.0064 0.0094
Echinococcus multilocularis phd:f box containing protein 0.002 0.0007 0.001
Loa Loa (eye worm) heterochromatin protein 1 0.0072 0.0111 0.1363
Entamoeba histolytica fatty acid elongase, putative 0.0662 0.1271 1
Entamoeba histolytica hypothetical protein 0.0049 0.0064 0.0505
Plasmodium falciparum phd finger protein, putative 0.006 0.0087 0.0087
Entamoeba histolytica tyrosine kinase, putative 0.0049 0.0064 0.0505
Loa Loa (eye worm) SH2 domain-containing protein 0.0037 0.0042 0.0515
Trypanosoma brucei Flagellum attachment zone protein 20 0.0049 0.0064 0.7963
Brugia malayi Nuclear hormone receptor E75 0.0021 0.0009 0.0114
Schistosoma mansoni ecdysone-induced protein 78c (dr-78) 0.0023 0.0014 0.0021
Trichomonas vaginalis TKL family protein kinase 0.0049 0.0064 0.0692
Leishmania major glucose transporter, lmgt1 0.003 0.0028 0.2725
Leishmania major protein kinase, putative 0.0049 0.0065 0.6385
Brugia malayi hypothetical protein 0.0049 0.0064 0.0791
Brugia malayi Bromodomain containing protein 0.0065 0.0096 0.1177
Trichomonas vaginalis TKL family protein kinase 0.0049 0.0064 0.0692
Toxoplasma gondii histone lysine acetyltransferase GCN5-B 0.005 0.0066 0.3049
Chlamydia trachomatis ATP-dependent Clp protease proteolytic subunit 0.0091 0.0148 0.014
Onchocerca volvulus 0.0049 0.0064 0.0598
Mycobacterium ulcerans aldehyde dehydrogenase 0.0068 0.0102 0.0102
Schistosoma mansoni tyrosine kinase 0.0049 0.0064 0.0094
Echinococcus granulosus Transcription factor JmjC domain containing protein 0.0198 0.0358 0.0527
Loa Loa (eye worm) isocitrate dehydrogenase 0.0047 0.0062 0.076
Schistosoma mansoni glucose transport protein 0.0097 0.016 0.0236
Schistosoma mansoni bromodomain-containing nuclear protein 1 brd1 0.006 0.0087 0.0129
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0026 0.002 0.0214
Brugia malayi SH2 domain containing protein 0.0037 0.0042 0.0515
Brugia malayi PHD-finger family protein 0.006 0.0087 0.1077
Echinococcus granulosus hepatocyte nuclear factor 4 alpha 0.0044 0.0055 0.0081
Toxoplasma gondii ATP-dependent Clp endopeptidase, proteolytic subunit ClpP domain-containing protein 0.0091 0.0148 0.6812
Echinococcus multilocularis receptor type guanylyl cyclase 0.0049 0.0064 0.0094
Trypanosoma brucei PHD-zinc-finger like domain containing protein, putative 0.002 0.0007 0.09
Echinococcus multilocularis tyrosine protein kinase Srms 0.0086 0.0138 0.0202
Onchocerca volvulus 0.0044 0.0055 0.0499
Trichomonas vaginalis TKL family protein kinase 0.0049 0.0064 0.0692
Echinococcus multilocularis Jumonji, AT rich interactive domain 1B 0.0023 0.0014 0.002
Loa Loa (eye worm) RhoGAP domain-containing protein 0.0037 0.0042 0.0515
Entamoeba histolytica protein kinase, putative 0.0049 0.0064 0.0505
Trypanosoma brucei AGC/RSK family serine/threonine kinase, putative 0.0049 0.0064 0.7963
Loa Loa (eye worm) calpain family protein 1 0.0058 0.0083 0.102
Echinococcus multilocularis solute carrier family 2, facilitated glucose 0.0097 0.016 0.0236
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0021 0.0009 0.0014
Toxoplasma gondii calcium dependent protein kinase CDPK8 0.0049 0.0065 0.3007
Trichomonas vaginalis TKL family protein kinase 0.0049 0.0064 0.0692
Echinococcus multilocularis retinoic acid receptor rxr beta a retinoic acid receptor rxr alpha a retinoic acid receptor rxr alpha 0.0021 0.0009 0.0014
Trichomonas vaginalis glucose transporter, putative 0.003 0.0028 0.03
Loa Loa (eye worm) hypothetical protein 0.0037 0.0042 0.0515
Mycobacterium tuberculosis Probable ATP-dependent CLP protease proteolytic subunit 2 ClpP2 (endopeptidase CLP 2) 0.006 0.0086 0.0086
Schistosoma mansoni hepatocyte nuclear factor 4-alpha (hnf-4-alpha) 0.0021 0.0009 0.0014
Trichomonas vaginalis TKL family protein kinase 0.0049 0.0064 0.0692
Trichomonas vaginalis TKL family protein kinase 0.0049 0.0064 0.0692
Loa Loa (eye worm) hypothetical protein 0.0086 0.0138 0.1696
Trichomonas vaginalis sugar transporter, putative 0.003 0.0028 0.03
Echinococcus granulosus retinal guanylyl cyclase 2 0.0049 0.0064 0.0094
Entamoeba histolytica fatty acid elongase, putative 0.0662 0.1271 1
Brugia malayi Probable tyrosine-protein kinase kin-31 0.0049 0.0064 0.0791
Leishmania major mitogen activated protein kinase, putative,map kinase, putative 0.0057 0.0081 0.7893
Schistosoma mansoni hypothetical protein 0.0173 0.0309 0.0454
Schistosoma mansoni jumonji domain containing protein 0.002 0.0007 0.001
Echinococcus multilocularis chromobox protein 1 0.0072 0.0111 0.0163
Loa Loa (eye worm) hypothetical protein 0.0021 0.0009 0.0114
Trichomonas vaginalis TKL family protein kinase 0.0049 0.0064 0.0692
Echinococcus granulosus histone lysine N methyltransferase MLL3 0.0018 0.0004 0.0005
Trypanosoma brucei glucose transporter, putative 0.003 0.0028 0.3453
Trichomonas vaginalis TKL family protein kinase 0.0049 0.0064 0.0692
Loa Loa (eye worm) hypothetical protein 0.006 0.0087 0.1077
Entamoeba histolytica hypothetical protein 0.0049 0.0064 0.0505
Echinococcus granulosus GPCR family 2 0.008 0.0126 0.0185
Entamoeba histolytica tyrosine kinase, putative 0.0049 0.0064 0.0505
Schistosoma mansoni aldehyde dehydrogenase 0.0068 0.0102 0.015
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD7 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0019 0.0005 0.0005
Schistosoma mansoni tyrosine kinase 0.0049 0.0064 0.0094
Trichomonas vaginalis TKL family protein kinase 0.0049 0.0064 0.0692
Brugia malayi Nuclear hormone receptor family member nhr-41 0.0044 0.0055 0.0678
Entamoeba histolytica hypothetical protein, conserved 0.0049 0.0064 0.0505
Echinococcus multilocularis Nuclear hormone receptor family member nhr 41 0.0044 0.0055 0.0081
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0044 0.0055 0.0081
Trichomonas vaginalis TKL family protein kinase 0.0049 0.0064 0.0692
Echinococcus granulosus tyrosine protein kinase 0.0049 0.0064 0.0094
Schistosoma mansoni shc transforming protein 0.0037 0.0042 0.0061
Trypanosoma brucei glucose transporter 2A 0.003 0.0028 0.3453
Loa Loa (eye worm) hypothetical protein 0.0021 0.0009 0.0114
Loa Loa (eye worm) hypothetical protein 0.0023 0.0014 0.0174
Echinococcus granulosus tyrosine protein kinase shark 0.0086 0.0138 0.0202
Echinococcus granulosus histone lysine N methyltransferase MLL3 0.0022 0.0011 0.0017
Entamoeba histolytica hypothetical protein 0.0037 0.0042 0.0329
Loa Loa (eye worm) TK protein kinase 0.0049 0.0064 0.0791
Loa Loa (eye worm) TK/CSK protein kinase 0.0049 0.0064 0.0791
Brugia malayi Protein kinase domain containing protein 0.0049 0.0064 0.0791
Schistosoma mansoni protein tyrosine kinase 0.0049 0.0064 0.0094
Echinococcus granulosus solute carrier family 2 facilitated glucose 0.0097 0.016 0.0236
Trichomonas vaginalis serine-threonine protein kinase, putative 0.0049 0.0064 0.0692
Loa Loa (eye worm) TK/FER protein kinase 0.0086 0.0138 0.1696
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0018 0.0005 0.0051
Echinococcus multilocularis SHC transforming protein 3 0.0037 0.0042 0.0061
Loa Loa (eye worm) hypothetical protein 0.0037 0.0042 0.0515
Echinococcus granulosus dual specificity testis-specific protein kinase 0.0049 0.0065 0.0096
Brugia malayi hypothetical protein 0.0276 0.0511 0.6293
Echinococcus granulosus receptor type guanylyl cyclase 0.0049 0.0064 0.0094
Leishmania major 4-coumarate:coa ligase-like protein 0.0027 0.0021 0.2014
Onchocerca volvulus 0.0037 0.0042 0.0355
Entamoeba histolytica protein kinase domain containing protein 0.0049 0.0064 0.0505
Trichomonas vaginalis TKL family protein kinase 0.0049 0.0064 0.0692
Entamoeba histolytica tyrosine kinase, putative 0.0049 0.0064 0.0505
Echinococcus granulosus mitogen-activated protein kinase kinase kinase 9 0.0049 0.0064 0.0094
Loa Loa (eye worm) hypothetical protein 0.0402 0.0759 0.9358
Schistosoma mansoni hypothetical protein 0.008 0.0126 0.0185
Brugia malayi orphan nuclear receptor NR2E1 0.0021 0.0009 0.0114
Echinococcus multilocularis retinal guanylyl cyclase 2 0.0049 0.0064 0.0094
Echinococcus multilocularis suppressor of cytokine signaling 7 0.0037 0.0042 0.0061
Echinococcus granulosus tyrosine protein kinase Src42A 0.0037 0.0042 0.0061
Plasmodium falciparum protein kinase, putative 0.0049 0.0065 0.0065
Schistosoma mansoni cpg binding protein 0.0063 0.0093 0.0137
Entamoeba histolytica serine/threonine kinase, putative 0.0049 0.0064 0.0505
Schistosoma mansoni protein kinase 0.0049 0.0065 0.0096
Entamoeba histolytica protein kinase, putative 0.0049 0.0064 0.0505
Plasmodium vivax SET domain protein, putative 0.0063 0.0092 0.0092
Plasmodium falciparum beta-ketoacyl-ACP synthase III 0.5097 1 1
Echinococcus granulosus chromobox protein 1 0.0072 0.0111 0.0163
Toxoplasma gondii CMGC kinase, MAPK family (ERK) MAPK-1 0.0057 0.0081 0.3717
Loa Loa (eye worm) TK/EPH protein kinase 0.0049 0.0064 0.0791
Loa Loa (eye worm) TK/FER protein kinase 0.0086 0.0138 0.1696
Loa Loa (eye worm) TK protein kinase 0.0049 0.0064 0.0791
Echinococcus granulosus histone acetyltransferase KAT2B 0.005 0.0066 0.0097
Brugia malayi Adenylate and Guanylate cyclase catalytic domain containing protein 0.0049 0.0064 0.0791
Schistosoma mansoni photoreceptor-specific nuclear receptor related 0.0044 0.0055 0.0081
Echinococcus granulosus SH2 motif 0.0037 0.0042 0.0061
Onchocerca volvulus Bile acid receptor homolog 0.0044 0.0055 0.0499
Trichomonas vaginalis TKL family protein kinase 0.0049 0.0064 0.0692
Loa Loa (eye worm) hypothetical protein 0.002 0.0007 0.0091
Echinococcus granulosus mitogen activated protein kinase 0.0057 0.0081 0.0119
Echinococcus granulosus 3'partial|tyrosine protein kinase Fgr 0.0086 0.0138 0.0202
Trichomonas vaginalis TKL family protein kinase 0.0049 0.0064 0.0692
Schistosoma mansoni tyrosine kinase 0.0086 0.0138 0.0202
Echinococcus multilocularis tyrosine protein kinase lyn tyrosine protein kinase blk 0.0086 0.0138 0.0202
Schistosoma mansoni tyrosine kinase 0.0049 0.0064 0.0094
Schistosoma mansoni suppressor of cytokine signaling 0.0037 0.0042 0.0061
Brugia malayi Protein kinase domain containing protein 0.0086 0.0138 0.1696
Brugia malayi acetyltransferase, GNAT family protein 0.0169 0.0301 0.3706
Trichomonas vaginalis conserved hypothetical protein 0.0097 0.016 0.1726
Mycobacterium ulcerans beta-ketoacyl synthase-like protein 0.5097 1 1
Schistosoma mansoni NADP-specific isocitrate dehydrogenase 0.0047 0.0062 0.0091
Schistosoma mansoni calpain-7 (C02 family) 0.0017 0.0002 0.0004
Echinococcus granulosus lysine specific demethylase 5A 0.0077 0.012 0.0176
Echinococcus multilocularis GPCR, family 2 0.008 0.0126 0.0185
Loa Loa (eye worm) serine/threonine protein kinase 0.0049 0.0064 0.0791
Echinococcus multilocularis dnaJ subfamily B 0.0901 0.1741 0.2561
Brugia malayi steroid hormone receptor 0.0044 0.0055 0.0678
Echinococcus multilocularis atpase aaa+ type core atpase aaa type core 0.0908 0.1755 0.2581
Echinococcus multilocularis NADP dependent isocitrate dehydrogenase 0.0047 0.0062 0.0091
Schistosoma mansoni tensin 0.0037 0.0042 0.0061
Echinococcus granulosus protein kinase 0.0049 0.0064 0.0094
Echinococcus multilocularis tyrosine protein kinase Blk 0.0086 0.0138 0.0202
Loa Loa (eye worm) TK/FER protein kinase 0.0049 0.0064 0.0791
Echinococcus multilocularis solute carrier family 2 facilitated glucose 0.0097 0.016 0.0236
Loa Loa (eye worm) hypothetical protein 0.0023 0.0014 0.0174
Entamoeba histolytica protein tyrosine kinase domain-containing protein 0.0049 0.0064 0.0505
Echinococcus multilocularis tyrosine protein kinase Btk29A 0.0086 0.0138 0.0202
Entamoeba histolytica tyrosine kinase, putative 0.0049 0.0064 0.0505
Echinococcus granulosus General substrate transporter 0.0084 0.0133 0.0196
Entamoeba histolytica protein kinase, putative 0.0049 0.0064 0.0505
Onchocerca volvulus 0.0086 0.0138 0.1398
Brugia malayi hypothetical protein 0.0019 0.0006 0.007
Trypanosoma brucei glucose transporter, putative 0.003 0.0028 0.3453
Trypanosoma cruzi mitogen-activated protein kinase 11, putative 0.0057 0.0081 1
Schistosoma mansoni hypothetical protein 0.008 0.0126 0.0185
Echinococcus granulosus SH2 domain containing protein 7 0.0037 0.0042 0.0061
Loa Loa (eye worm) nuclear receptor NHR-67 0.0021 0.0009 0.0114
Trypanosoma cruzi cysteine peptidase, Clan CA, family C2, putative 0.0017 0.0002 0.0298
Trichomonas vaginalis chromobox protein, putative 0.0044 0.0054 0.0584
Brugia malayi Sugar transporter family protein 0.0097 0.016 0.1973
Loa Loa (eye worm) hypothetical protein 0.0049 0.0064 0.0791
Echinococcus granulosus tyrosine protein kinase Fyn 0.0086 0.0138 0.0202
Trichomonas vaginalis TKL family protein kinase 0.0049 0.0064 0.0692
Echinococcus granulosus cpg binding protein 0.0067 0.01 0.0147
Schistosoma mansoni protein kinase 0.0049 0.0065 0.0096

Activities

Activity type Activity value Assay description Source Reference
MIC (functional) > 20 ug ml-1 Lowest concentration required to inhibit 90-100% of the visible growth of Candida albicans when compared to controls ChEMBL. 10999480
MIC (functional) > 20 ug ml-1 Tested in vitro for lowest concentration required to inhibit 90-100% of the visible growth of Candida neoformans ChEMBL. 10999480
MIC (functional) > 20 ug ml-1 Lowest concentration required to inhibit the growth of Aspergillus fumigatus ChEMBL. 10999480

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
In any case, if you have information about papers containing relevant validation data for this target, please log in using your TDR Targets username and password and send them to us using the corresponding form in this page (only visible to registered users) or contact us.

External resources for this compound

Bibliographic References

1 literature reference was collected for this gene.

If you have references for this compound, please enter them in a user comment (below) or Contact us.