Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Echinococcus granulosus | jumonji domain containing protein | 0.0042 | 0.0166 | 0.0403 |
Echinococcus multilocularis | suppression of tumorigenicity 18 protein | 0.0057 | 0.0244 | 0.0593 |
Trypanosoma brucei | importin beta-1 subunit, putative | 0.0026 | 0.008 | 0.0268 |
Brugia malayi | O-Glycosyl hydrolase family 30 protein | 0.0269 | 0.14 | 0.3403 |
Echinococcus multilocularis | inositol monophosphatase 1 | 0.0034 | 0.012 | 0.0291 |
Schistosoma mansoni | hypothetical protein | 0.003 | 0.0101 | 0.0238 |
Trypanosoma brucei | metacaspase 5, putative | 0.004 | 0.0156 | 0.0525 |
Echinococcus multilocularis | endonuclease exonuclease phosphatase | 0.0196 | 0.1001 | 0.2436 |
Trypanosoma brucei | inositol-1(or 4)-monophosphatase 1, putative | 0.0034 | 0.012 | 0.0403 |
Trypanosoma cruzi | mitogen-activated protein kinase 11, putative | 0.0053 | 0.0227 | 0.0762 |
Schistosoma mansoni | bromodomain containing protein | 0.0066 | 0.0295 | 0.0709 |
Chlamydia trachomatis | dihydrofolate reductase | 0.0767 | 0.411 | 1 |
Loa Loa (eye worm) | PHD-finger family protein | 0.0021 | 0.0053 | 0.0127 |
Trichomonas vaginalis | chromobox protein, putative | 0.0038 | 0.0145 | 0.1039 |
Echinococcus granulosus | GTP binding nuclear protein Ran | 0.0019 | 0.0042 | 0.0101 |
Loa Loa (eye worm) | jmjC domain-containing protein | 0.0063 | 0.0277 | 0.0672 |
Schistosoma mansoni | NADP-specific isocitrate dehydrogenase | 0.0014 | 0.0015 | 0.0027 |
Entamoeba histolytica | myo-inositol monophosphatase, putative | 0.0034 | 0.012 | 0.072 |
Echinococcus granulosus | chromobox protein 1 | 0.0064 | 0.0283 | 0.0688 |
Brugia malayi | Cell death protein 3 precursor | 0.0078 | 0.0362 | 0.0878 |
Trypanosoma cruzi | mitogen activated protein kinase 4, putative | 0.0053 | 0.0227 | 0.0762 |
Echinococcus multilocularis | apoptotic protease activating factor 1 | 0.0038 | 0.0141 | 0.0343 |
Echinococcus multilocularis | Protein lozenge | 0.0058 | 0.0251 | 0.061 |
Onchocerca volvulus | 0.0213 | 0.1093 | 0.4262 | |
Leishmania major | myo-inositol-1(or 4)-monophosphatase 1, putative | 0.0034 | 0.012 | 0.0403 |
Plasmodium vivax | hypothetical protein, conserved | 0.004 | 0.0156 | 0.0478 |
Echinococcus multilocularis | Transcription factor, JmjC domain containing protein | 0.0099 | 0.0477 | 0.116 |
Leishmania major | dihydrofolate reductase-thymidylate synthase | 0.0559 | 0.2981 | 1 |
Echinococcus multilocularis | mitogen activated protein kinase 3 | 0.0053 | 0.0227 | 0.0552 |
Loa Loa (eye worm) | hypothetical protein | 0.0035 | 0.0129 | 0.0312 |
Schistosoma mansoni | ran | 0.0019 | 0.0042 | 0.0093 |
Trypanosoma cruzi | dihydrofolate reductase-thymidylate synthase | 0.0559 | 0.2981 | 1 |
Trypanosoma cruzi | myo-inositol-1(or 4)-monophosphatase 1, putative | 0.0034 | 0.012 | 0.0403 |
Echinococcus granulosus | apoptotic protease activating factor 1 | 0.0038 | 0.0141 | 0.0343 |
Echinococcus granulosus | methyl CpG binding domain protein 2 | 0.0018 | 0.0033 | 0.0079 |
Trypanosoma brucei | recA bacterial DNA recombination protein, putative | 0.0035 | 0.0124 | 0.0417 |
Brugia malayi | hypothetical protein | 0.0101 | 0.0487 | 0.1182 |
Trichomonas vaginalis | CMGC family protein kinase | 0.0053 | 0.0227 | 0.1623 |
Loa Loa (eye worm) | inositol-1 | 0.0034 | 0.012 | 0.029 |
Entamoeba histolytica | hypothetical protein | 0.0082 | 0.0383 | 0.2298 |
Brugia malayi | jmjC domain containing protein | 0.0099 | 0.0477 | 0.1159 |
Brugia malayi | Bromodomain containing protein | 0.0078 | 0.0361 | 0.0876 |
Giardia lamblia | PHD finger protein 15 | 0.003 | 0.0101 | 0.0366 |
Echinococcus multilocularis | dual specificity | 0.0082 | 0.0383 | 0.0932 |
Echinococcus granulosus | GPCR family 2 | 0.0016 | 0.0026 | 0.0061 |
Plasmodium vivax | hypothetical protein, conserved | 0.003 | 0.0101 | 0.0292 |
Trypanosoma cruzi | CMGC/DYRK protein kinase, putative | 0.0082 | 0.0383 | 0.1286 |
Schistosoma mansoni | jumonji domain containing protein | 0.0079 | 0.0366 | 0.0882 |
Echinococcus multilocularis | cadherin EGF LAG seven pass G type receptor | 0.0016 | 0.0026 | 0.0061 |
Trypanosoma cruzi | ISWI complex protein | 0.0016 | 0.0023 | 0.0077 |
Schistosoma mansoni | methyl-cpg binding protein mbd | 0.0018 | 0.0033 | 0.0071 |
Echinococcus multilocularis | peregrin | 0.0033 | 0.0115 | 0.0279 |
Mycobacterium tuberculosis | Hypothetical protein | 0.0101 | 0.0487 | 0.0473 |
Onchocerca volvulus | Glucosylceramidase homolog | 0.0176 | 0.0896 | 0.3426 |
Loa Loa (eye worm) | follicle stimulating hormone receptor | 0.0217 | 0.1117 | 0.2715 |
Trichomonas vaginalis | conserved hypothetical protein | 0.004 | 0.0156 | 0.1118 |
Echinococcus multilocularis | caspase 3 | 0.0067 | 0.0298 | 0.0725 |
Brugia malayi | Dihydrofolate reductase | 0.0767 | 0.411 | 1 |
Echinococcus granulosus | SAM and MBT domain containing protein | 0.005 | 0.0206 | 0.0502 |
Loa Loa (eye worm) | hypothetical protein | 0.005 | 0.0206 | 0.05 |
Giardia lamblia | Kinase, CMGC MAPK | 0.0053 | 0.0227 | 0.114 |
Echinococcus granulosus | bloom syndrome protein | 0.0022 | 0.0056 | 0.0135 |
Loa Loa (eye worm) | hypothetical protein | 0.0026 | 0.008 | 0.0192 |
Schistosoma mansoni | caspase-7 (C14 family) | 0.0107 | 0.0519 | 0.1254 |
Echinococcus multilocularis | methyl CpG binding domain protein 2 | 0.0018 | 0.0033 | 0.0079 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0025 | 0.0074 | 0.0528 |
Echinococcus multilocularis | caspase 3, apoptosis cysteine peptidase | 0.0107 | 0.0519 | 0.1261 |
Leishmania major | isocitrate dehydrogenase [NADP], mitochondrial precursor, putative | 0.0014 | 0.0015 | 0.005 |
Brugia malayi | Corticotropin releasing factor receptor 2 precursor, putative | 0.0052 | 0.0219 | 0.053 |
Trichomonas vaginalis | glucosylceramidase, putative | 0.0269 | 0.14 | 1 |
Trypanosoma cruzi | myo-inositol-1(or 4)-monophosphatase 1, putative | 0.0034 | 0.012 | 0.0403 |
Echinococcus multilocularis | NADP dependent isocitrate dehydrogenase | 0.0014 | 0.0015 | 0.0035 |
Echinococcus granulosus | dual specificity | 0.0082 | 0.0383 | 0.0932 |
Loa Loa (eye worm) | hypothetical protein | 0.0018 | 0.0033 | 0.0077 |
Schistosoma mansoni | tyrosyl-DNA phosphodiesterase | 0.0069 | 0.031 | 0.0746 |
Echinococcus multilocularis | snurportin 1 | 0.0282 | 0.1469 | 0.3574 |
Trichomonas vaginalis | DNA helicase recq, putative | 0.0022 | 0.0056 | 0.0398 |
Echinococcus multilocularis | zinc finger protein | 0.002 | 0.0047 | 0.0114 |
Schistosoma mansoni | methyl-cpg binding protein mbd | 0.0018 | 0.0033 | 0.0071 |
Echinococcus granulosus | importin subunit beta 1 | 0.0026 | 0.008 | 0.0193 |
Loa Loa (eye worm) | heterochromatin protein 1 | 0.0064 | 0.0283 | 0.0687 |
Trichomonas vaginalis | CMGC family protein kinase | 0.0053 | 0.0227 | 0.1623 |
Echinococcus granulosus | bromodomain adjacent to zinc finger domain | 0.0037 | 0.014 | 0.0339 |
Loa Loa (eye worm) | hypothetical protein | 0.0044 | 0.0178 | 0.043 |
Brugia malayi | Importin beta-1 subunit | 0.0026 | 0.008 | 0.0192 |
Brugia malayi | Bloom's syndrome protein homolog | 0.0022 | 0.0056 | 0.0133 |
Giardia lamblia | DNA repair protein RAD52 | 0.0318 | 0.1668 | 1 |
Echinococcus multilocularis | bromodomain adjacent to zinc finger domain | 0.0062 | 0.0274 | 0.0667 |
Toxoplasma gondii | PHD-finger domain-containing protein | 0.003 | 0.0101 | 0.0292 |
Schistosoma mansoni | importin beta-1 | 0.0026 | 0.008 | 0.0185 |
Schistosoma mansoni | hypothetical protein | 0.0021 | 0.0053 | 0.012 |
Schistosoma mansoni | serine/threonine protein kinase | 0.0053 | 0.0227 | 0.0544 |
Echinococcus multilocularis | chromodomain helicase DNA binding protein 4 | 0.0012 | 0.0004 | 0.0008 |
Trypanosoma cruzi | tyrosyl-DNA Phosphodiesterase (Tdp1), putative | 0.0069 | 0.031 | 0.1041 |
Loa Loa (eye worm) | CHromoDomain protein family member | 0.0012 | 0.0004 | 0.0007 |
Trichomonas vaginalis | Importin beta-1 subunit, putative | 0.0021 | 0.0053 | 0.0376 |
Schistosoma mansoni | chromobox protein | 0.0064 | 0.0283 | 0.068 |
Schistosoma mansoni | scm-relatedprotein containing 4 mbt domains (sfmbt) | 0.005 | 0.0206 | 0.0494 |
Toxoplasma gondii | bifunctional dihydrofolate reductase-thymidylate synthase | 0.0559 | 0.2981 | 1 |
Echinococcus multilocularis | caspase 2 | 0.0078 | 0.0362 | 0.0879 |
Loa Loa (eye worm) | transcription factor SMAD2 | 0.0109 | 0.0531 | 0.1289 |
Trichomonas vaginalis | Clan CD, family C14, metacaspase-like cysteine peptidase | 0.004 | 0.0156 | 0.1118 |
Schistosoma mansoni | ran | 0.0019 | 0.0042 | 0.0093 |
Echinococcus multilocularis | caspase 8 | 0.004 | 0.0156 | 0.038 |
Echinococcus multilocularis | jumonji domain containing protein | 0.0042 | 0.0166 | 0.0403 |
Mycobacterium tuberculosis | Dihydrofolate reductase DfrA (DHFR) (tetrahydrofolate dehydrogenase) | 0.0767 | 0.411 | 0.4101 |
Schistosoma mansoni | zinc finger protein | 0.002 | 0.0047 | 0.0105 |
Onchocerca volvulus | Heterochromatin protein 1 homolog | 0.0038 | 0.0145 | 0.0241 |
Mycobacterium ulcerans | dihydrofolate reductase DfrA | 0.0767 | 0.411 | 1 |
Echinococcus granulosus | caspase 3 apoptosis cysteine peptidase | 0.0107 | 0.0519 | 0.1261 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0036 | 0.0131 | 0.0933 |
Brugia malayi | Protein kinase domain containing protein | 0.0082 | 0.0383 | 0.093 |
Loa Loa (eye worm) | mbt repeat family protein | 0.005 | 0.0206 | 0.05 |
Brugia malayi | chromobox protein homolog 3 | 0.0036 | 0.0131 | 0.0316 |
Brugia malayi | C2-HC type zinc finger protein C.e-MyT1 | 0.0057 | 0.0244 | 0.0591 |
Loa Loa (eye worm) | hypothetical protein | 0.0028 | 0.0089 | 0.0213 |
Schistosoma mansoni | dihydrofolate reductase | 0.0767 | 0.411 | 1 |
Schistosoma mansoni | hypothetical protein | 0.0016 | 0.0023 | 0.0046 |
Echinococcus multilocularis | bromodomain adjacent to zinc finger domain | 0.0037 | 0.014 | 0.0339 |
Echinococcus multilocularis | diuretic hormone 44 receptor GPRdih2 | 0.0016 | 0.0026 | 0.0061 |
Schistosoma mansoni | caspase-3 (C14 family) | 0.0107 | 0.0519 | 0.1254 |
Brugia malayi | isocitrate dehydrogenase | 0.0014 | 0.0015 | 0.0034 |
Loa Loa (eye worm) | CMGC/DYRK/DYRK1 protein kinase | 0.0082 | 0.0383 | 0.093 |
Echinococcus multilocularis | isocitrate dehydrogenase 2 (NADP+) | 0.0014 | 0.0015 | 0.0035 |
Toxoplasma gondii | GTP-binding nuclear protein ran/tc4 | 0.0019 | 0.0042 | 0.0091 |
Schistosoma mansoni | blooms syndrome DNA helicase | 0.0017 | 0.0031 | 0.0065 |
Brugia malayi | mucosa associated lymphoid tissue lymphoma translocation protein 1 | 0.004 | 0.0156 | 0.0378 |
Loa Loa (eye worm) | GTP-binding nuclear protein RAN/TC4 | 0.0019 | 0.0042 | 0.0099 |
Loa Loa (eye worm) | RecQ helicase | 0.0022 | 0.0056 | 0.0133 |
Echinococcus granulosus | inositol monophosphatase 1 | 0.0034 | 0.012 | 0.0291 |
Schistosoma mansoni | hypothetical protein | 0.0016 | 0.0026 | 0.0053 |
Plasmodium vivax | bifunctional dihydrofolate reductase-thymidylate synthase, putative | 0.0559 | 0.2981 | 1 |
Trichomonas vaginalis | glucosylceramidase, putative | 0.0269 | 0.14 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0038 | 0.0141 | 0.0342 |
Trypanosoma cruzi | mitogen activated protein kinase 2, putative | 0.0053 | 0.0227 | 0.0762 |
Echinococcus multilocularis | neuropeptide s receptor | 0.0485 | 0.2578 | 0.6272 |
Echinococcus multilocularis | chromobox protein 1 | 0.0064 | 0.0283 | 0.0688 |
Plasmodium vivax | ADP-dependent DNA helicase RecQ, putative | 0.0015 | 0.0017 | 0.0007 |
Entamoeba histolytica | DNA repair and recombination protein RAD52, putative | 0.0318 | 0.1668 | 1 |
Mycobacterium ulcerans | recombinase A | 0.0112 | 0.0548 | 0.1071 |
Echinococcus multilocularis | isocitrate dehydrogenase | 0.0014 | 0.0015 | 0.0035 |
Schistosoma mansoni | subfamily C14A unassigned peptidase (C14 family) | 0.004 | 0.0156 | 0.0372 |
Echinococcus granulosus | mitogen activated protein kinase | 0.0053 | 0.0227 | 0.0552 |
Schistosoma mansoni | caspase-7 (C14 family) | 0.0078 | 0.0362 | 0.0871 |
Loa Loa (eye worm) | hypothetical protein | 0.0036 | 0.0131 | 0.0316 |
Trypanosoma cruzi | metacaspase, putative | 0.004 | 0.0156 | 0.0525 |
Echinococcus multilocularis | caspase | 0.0107 | 0.0519 | 0.1261 |
Echinococcus multilocularis | NADP dependent isocitrate dehydrogenase | 0.0014 | 0.0015 | 0.0035 |
Trichomonas vaginalis | glucosylceramidase, putative | 0.0269 | 0.14 | 1 |
Echinococcus multilocularis | tyrosyl DNA phosphodiesterase 1 | 0.0069 | 0.031 | 0.0754 |
Mycobacterium ulcerans | thymidylate synthase | 0.0213 | 0.1093 | 0.2439 |
Trypanosoma cruzi | GTP-binding nuclear protein rtb2, putative | 0.0019 | 0.0042 | 0.014 |
Mycobacterium leprae | DIHYDROFOLATE REDUCTASE DFRA (DHFR) (TETRAHYDROFOLATE DEHYDROGENASE) | 0.0767 | 0.411 | 1 |
Brugia malayi | calcium-independent alpha-latrotoxin receptor 2, putative | 0.0016 | 0.0026 | 0.006 |
Plasmodium falciparum | ADP-dependent DNA helicase RecQ | 0.0019 | 0.0041 | 0.0089 |
Echinococcus granulosus | caspase 8 | 0.004 | 0.0156 | 0.038 |
Trypanosoma cruzi | importin beta-1 subunit, putative | 0.0021 | 0.0053 | 0.0176 |
Brugia malayi | Bromodomain containing protein | 0.0033 | 0.0115 | 0.0277 |
Echinococcus multilocularis | microtubule associated protein 2 | 0.0718 | 0.3846 | 0.9358 |
Schistosoma mansoni | microtubule-associated protein tau | 0.0718 | 0.3846 | 0.9358 |
Loa Loa (eye worm) | PHD-finger family protein | 0.003 | 0.0101 | 0.0244 |
Trypanosoma brucei | isocitrate dehydrogenase, putative | 0.0014 | 0.0015 | 0.005 |
Trypanosoma brucei | dihydrofolate reductase-thymidylate synthase | 0.0559 | 0.2981 | 1 |
Trichomonas vaginalis | glucosylceramidase, putative | 0.0176 | 0.0896 | 0.6404 |
Leishmania major | tyrosyl-DNA phosphodiesterase 1 | 0.0069 | 0.031 | 0.1041 |
Schistosoma mansoni | jumonji/arid domain-containing protein | 0.0039 | 0.0147 | 0.0349 |
Trypanosoma cruzi | dihydrofolate reductase-thymidylate synthase, putative | 0.0101 | 0.0487 | 0.1633 |
Loa Loa (eye worm) | dihydrofolate reductase | 0.0767 | 0.411 | 1 |
Echinococcus multilocularis | NADP dependent isocitrate dehydrogenase | 0.0014 | 0.0015 | 0.0035 |
Brugia malayi | hypothetical protein | 0.0461 | 0.2446 | 0.595 |
Echinococcus granulosus | Transcription factor JmjC domain containing protein | 0.0099 | 0.0477 | 0.116 |
Brugia malayi | dihydrofolate reductase family protein | 0.0767 | 0.411 | 1 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0101 | 0.0487 | 0.3477 |
Mycobacterium leprae | RECA PROTEIN (RECOMBINASE A) [CONTAINS: Mle RECA INTEIN]. | 0.0112 | 0.0548 | 0.1114 |
Loa Loa (eye worm) | thymidylate synthase | 0.0213 | 0.1093 | 0.2658 |
Toxoplasma gondii | ICE family protease (caspase) p20 domain-containing protein | 0.004 | 0.0156 | 0.0478 |
Loa Loa (eye worm) | hypothetical protein | 0.0074 | 0.0337 | 0.0817 |
Onchocerca volvulus | 0.0461 | 0.2446 | 1 | |
Trichomonas vaginalis | glucosylceramidase, putative | 0.0269 | 0.14 | 1 |
Trichomonas vaginalis | importin beta-1, putative | 0.0021 | 0.0053 | 0.0376 |
Brugia malayi | Bromodomain containing protein | 0.004 | 0.0153 | 0.037 |
Toxoplasma gondii | HEAT repeat-containing protein | 0.0026 | 0.008 | 0.0219 |
Trichomonas vaginalis | glucosylceramidase, putative | 0.0176 | 0.0896 | 0.6404 |
Trypanosoma cruzi | metacaspase, putative | 0.004 | 0.0156 | 0.0525 |
Mycobacterium tuberculosis | Inositol-1-monophosphatase SuhB | 0.003 | 0.0101 | 0.0086 |
Echinococcus multilocularis | importin subunit beta 1 | 0.0026 | 0.008 | 0.0193 |
Echinococcus granulosus | microtubule associated protein 2 | 0.0718 | 0.3846 | 0.9358 |
Onchocerca volvulus | 0.0038 | 0.0141 | 0.0224 | |
Plasmodium falciparum | metacaspase-like protein | 0.004 | 0.0156 | 0.0478 |
Trypanosoma brucei | metacaspase MCA2 | 0.004 | 0.0156 | 0.0525 |
Trichomonas vaginalis | glucosylceramidase, putative | 0.0269 | 0.14 | 1 |
Trichomonas vaginalis | CMGC family protein kinase | 0.0053 | 0.0227 | 0.1623 |
Trypanosoma cruzi | mitogen-activated protein kinase 11, putative | 0.0053 | 0.0227 | 0.0762 |
Loa Loa (eye worm) | MH2 domain-containing protein | 0.0109 | 0.0531 | 0.1289 |
Trichomonas vaginalis | conserved hypothetical protein | 0.004 | 0.0156 | 0.1118 |
Echinococcus granulosus | PHD finger protein rhinoceros | 0.003 | 0.0101 | 0.0246 |
Plasmodium falciparum | importin beta, putative | 0.0026 | 0.008 | 0.0219 |
Plasmodium vivax | GTP-binding nuclear protein RAN/TC4, putative | 0.0019 | 0.0042 | 0.0091 |
Trypanosoma brucei | importin beta-1 subunit, putative | 0.0026 | 0.008 | 0.0268 |
Trypanosoma brucei | ISWI complex protein | 0.0016 | 0.0023 | 0.0077 |
Loa Loa (eye worm) | CMGC/MAPK/ERK1 protein kinase | 0.0053 | 0.0227 | 0.055 |
Echinococcus multilocularis | SAM and MBT domain containing protein | 0.005 | 0.0206 | 0.0502 |
Trypanosoma brucei | Metacaspase-4 | 0.004 | 0.0156 | 0.0525 |
Brugia malayi | mbt repeat family protein | 0.005 | 0.0206 | 0.05 |
Loa Loa (eye worm) | hypothetical protein | 0.003 | 0.0101 | 0.0244 |
Trichomonas vaginalis | ran, putative | 0.0019 | 0.0042 | 0.0299 |
Trypanosoma cruzi | metacaspase 5, putative | 0.004 | 0.0156 | 0.0525 |
Brugia malayi | CHD4 protein | 0.0012 | 0.0004 | 0.0007 |
Trypanosoma cruzi | tyrosyl-DNA Phosphodiesterase (Tdp1), putative | 0.0069 | 0.031 | 0.1041 |
Echinococcus granulosus | mitogen activated protein kinase 3 | 0.0053 | 0.0227 | 0.0552 |
Trichomonas vaginalis | Clan CD, family C14, metacaspase-like cysteine peptidase | 0.004 | 0.0156 | 0.1118 |
Schistosoma mansoni | bromodomain-containing nuclear protein 1 brd1 | 0.003 | 0.0101 | 0.0238 |
Echinococcus multilocularis | bloom syndrome protein | 0.0022 | 0.0056 | 0.0135 |
Schistosoma mansoni | hypothetical protein | 0.0302 | 0.1579 | 0.3837 |
Onchocerca volvulus | Alhambra homolog | 0.003 | 0.0101 | 0.0054 |
Entamoeba histolytica | hypothetical protein | 0.0091 | 0.0429 | 0.2571 |
Loa Loa (eye worm) | hypothetical protein | 0.0078 | 0.0362 | 0.0878 |
Brugia malayi | thymidylate synthase | 0.0213 | 0.1093 | 0.2658 |
Schistosoma mansoni | hypothetical protein | 0.0016 | 0.0026 | 0.0053 |
Echinococcus multilocularis | PHD finger protein rhinoceros | 0.003 | 0.0101 | 0.0246 |
Plasmodium vivax | importin-beta 2, putative | 0.0026 | 0.008 | 0.0219 |
Entamoeba histolytica | protein kinase, putative | 0.0082 | 0.0383 | 0.2298 |
Trichomonas vaginalis | conserved hypothetical protein | 0.004 | 0.0156 | 0.1118 |
Trichomonas vaginalis | chromobox protein, putative | 0.0038 | 0.0145 | 0.1039 |
Loa Loa (eye worm) | hypothetical protein | 0.0052 | 0.0219 | 0.053 |
Wolbachia endosymbiont of Brugia malayi | recombinase A | 0.0112 | 0.0548 | 1 |
Brugia malayi | Isocitrate dehydrogenase | 0.0014 | 0.0015 | 0.0034 |
Trichomonas vaginalis | glucosylceramidase, putative | 0.0176 | 0.0896 | 0.6404 |
Schistosoma mansoni | hypothetical protein | 0.0282 | 0.1469 | 0.3569 |
Schistosoma mansoni | myelin transcription factor 1 myt1 | 0.0057 | 0.0244 | 0.0585 |
Schistosoma mansoni | chromobox protein | 0.0064 | 0.0283 | 0.068 |
Brugia malayi | jmjC domain containing protein | 0.0039 | 0.0147 | 0.0355 |
Brugia malayi | follicle stimulating hormone receptor | 0.0217 | 0.1117 | 0.2715 |
Mycobacterium tuberculosis | Probable replicative DNA helicase DnaB | 0.1737 | 0.9389 | 0.9388 |
Brugia malayi | Heterochromatin protein 1 | 0.0064 | 0.0283 | 0.0687 |
Brugia malayi | MH2 domain containing protein | 0.0109 | 0.0531 | 0.1289 |
Echinococcus granulosus | polycomb protein SCMH1 | 0.005 | 0.0206 | 0.0502 |
Trypanosoma brucei | isocitrate dehydrogenase [NADP], mitochondrial precursor, putative | 0.0014 | 0.0015 | 0.005 |
Loa Loa (eye worm) | hypothetical protein | 0.0081 | 0.0378 | 0.0918 |
Trichomonas vaginalis | Clan CD, family C14, metacaspase-like cysteine peptidase | 0.004 | 0.0156 | 0.1118 |
Schistosoma mansoni | lozenge | 0.0058 | 0.0251 | 0.0602 |
Entamoeba histolytica | protein kinase domain containing protein | 0.0082 | 0.0383 | 0.2298 |
Plasmodium vivax | metacaspase 1, putative | 0.004 | 0.0156 | 0.0478 |
Trichomonas vaginalis | DNA helicase recq1, putative | 0.0022 | 0.0056 | 0.0398 |
Schistosoma mansoni | jumonji/arid domain-containing protein | 0.0039 | 0.0147 | 0.0349 |
Brugia malayi | RNA, U transporter 1 | 0.0075 | 0.0344 | 0.0836 |
Echinococcus granulosus | chromodomain helicase DNA binding protein 4 | 0.0012 | 0.0004 | 0.0008 |
Loa Loa (eye worm) | pigment dispersing factor receptor c | 0.0052 | 0.0219 | 0.053 |
Toxoplasma gondii | inositol(myo)-1(or 4)-monophosphatase 2, putative | 0.0034 | 0.012 | 0.0355 |
Plasmodium falciparum | metacaspase 1 | 0.004 | 0.0156 | 0.0478 |
Trichomonas vaginalis | Importin beta-1 subunit, putative | 0.0021 | 0.0053 | 0.0376 |
Echinococcus granulosus | fetal alzheimer antigen falz | 0.0023 | 0.0064 | 0.0155 |
Schistosoma mansoni | histone-lysine n-methyltransferase setb1 | 0.0018 | 0.0033 | 0.0071 |
Schistosoma mansoni | sex comb on midleg homolog | 0.005 | 0.0206 | 0.0494 |
Trichomonas vaginalis | glucosylceramidase, putative | 0.0176 | 0.0896 | 0.6404 |
Loa Loa (eye worm) | hypothetical protein | 0.0081 | 0.0378 | 0.0918 |
Echinococcus granulosus | NADP dependent isocitrate dehydrogenase | 0.0014 | 0.0015 | 0.0035 |
Loa Loa (eye worm) | isocitrate dehydrogenase | 0.0014 | 0.0015 | 0.0034 |
Trypanosoma cruzi | CMGC/DYRK protein kinase, putative | 0.0082 | 0.0383 | 0.1286 |
Echinococcus granulosus | transcription factor Dp 1 | 0.004 | 0.0153 | 0.0371 |
Brugia malayi | Calcitonin receptor-like protein seb-1 | 0.0052 | 0.0219 | 0.053 |
Loa Loa (eye worm) | hypothetical protein | 0.0461 | 0.2446 | 0.595 |
Echinococcus multilocularis | fetal alzheimer antigen, falz | 0.0023 | 0.0064 | 0.0155 |
Trichomonas vaginalis | chromobox protein, putative | 0.0064 | 0.0283 | 0.2023 |
Trypanosoma cruzi | DNA repair protein, putative | 0.0035 | 0.0124 | 0.0417 |
Brugia malayi | PHD-finger family protein | 0.003 | 0.0101 | 0.0244 |
Trypanosoma cruzi | GTP-binding nuclear protein rtb2, putative | 0.0019 | 0.0042 | 0.014 |
Toxoplasma gondii | ICE family protease (caspase) p20 domain-containing protein | 0.004 | 0.0156 | 0.0478 |
Trypanosoma brucei | CMGC/DYRK protein kinase, putative | 0.0082 | 0.0383 | 0.1286 |
Trichomonas vaginalis | glucosylceramidase, putative | 0.0269 | 0.14 | 1 |
Toxoplasma gondii | PHD-finger domain-containing protein | 0.003 | 0.0101 | 0.0292 |
Echinococcus granulosus | neuropeptide s receptor | 0.0485 | 0.2578 | 0.6272 |
Trypanosoma cruzi | metacaspase, putative | 0.004 | 0.0156 | 0.0525 |
Leishmania major | serine/threonine-protein kinase, putative,protein kinase, putative | 0.0082 | 0.0383 | 0.1286 |
Loa Loa (eye worm) | hypothetical protein | 0.004 | 0.0154 | 0.0371 |
Echinococcus granulosus | zinc finger protein | 0.002 | 0.0047 | 0.0114 |
Mycobacterium tuberculosis | Probable thymidylate synthase ThyA (ts) (TSASE) | 0.0213 | 0.1093 | 0.108 |
Trichomonas vaginalis | glucosylceramidase, putative | 0.0186 | 0.0948 | 0.6774 |
Loa Loa (eye worm) | latrophilin receptor protein 2 | 0.0016 | 0.0026 | 0.006 |
Brugia malayi | Latrophilin receptor protein 2 | 0.0016 | 0.0026 | 0.006 |
Trichomonas vaginalis | glucosylceramidase, putative | 0.0186 | 0.0948 | 0.6774 |
Echinococcus granulosus | chromobox protein 1 | 0.0064 | 0.0283 | 0.0688 |
Brugia malayi | Tyrosyl-DNA phosphodiesterase family protein | 0.0069 | 0.031 | 0.0753 |
Loa Loa (eye worm) | hypothetical protein | 0.0042 | 0.0167 | 0.0404 |
Entamoeba histolytica | Rad52/22 family double-strand break repair protein, putative | 0.0091 | 0.0429 | 0.2571 |
Trichomonas vaginalis | chromobox protein, putative | 0.0064 | 0.0283 | 0.2023 |
Trichomonas vaginalis | Clan CD, family C14, metacaspase-like cysteine peptidase | 0.004 | 0.0156 | 0.1118 |
Echinococcus granulosus | peregrin | 0.0033 | 0.0115 | 0.0279 |
Loa Loa (eye worm) | jmjC domain-containing protein | 0.0039 | 0.0147 | 0.0355 |
Loa Loa (eye worm) | bromodomain containing protein | 0.0018 | 0.0036 | 0.0086 |
Schistosoma mansoni | sex comb on midleg homolog | 0.005 | 0.0206 | 0.0494 |
Loa Loa (eye worm) | hypothetical protein | 0.0016 | 0.0026 | 0.006 |
Mycobacterium leprae | Conserved hypothetical protein | 0.0659 | 0.3523 | 0.8535 |
Loa Loa (eye worm) | nucleolar RNA-associated protein alpha | 0.0282 | 0.1469 | 0.3573 |
Loa Loa (eye worm) | runx1 | 0.0058 | 0.0251 | 0.0608 |
Echinococcus multilocularis | transcription factor Dp 1 | 0.004 | 0.0153 | 0.0371 |
Trichomonas vaginalis | Clan CD, family C14, metacaspase-like cysteine peptidase | 0.004 | 0.0156 | 0.1118 |
Echinococcus multilocularis | thymidylate synthase | 0.0213 | 0.1093 | 0.2659 |
Schistosoma mansoni | zinc finger protein | 0.0016 | 0.0023 | 0.0046 |
Echinococcus multilocularis | lysine specific demethylase 5A | 0.0037 | 0.0136 | 0.033 |
Leishmania major | mitogen activated protein kinase, putative,map kinase, putative | 0.0053 | 0.0227 | 0.0762 |
Echinococcus multilocularis | neuropeptide receptor A26 | 0.0485 | 0.2578 | 0.6272 |
Brugia malayi | PHD-finger family protein | 0.0026 | 0.0077 | 0.0186 |
Echinococcus granulosus | suppression of tumorigenicity 18 protein | 0.0057 | 0.0244 | 0.0593 |
Brugia malayi | Cytochrome P450 family protein | 0.0027 | 0.0084 | 0.0202 |
Schistosoma mansoni | hypothetical protein | 0.0016 | 0.0026 | 0.0053 |
Entamoeba histolytica | Ran family GTPase | 0.0019 | 0.0042 | 0.0251 |
Leishmania major | hypothetical protein, conserved | 0.0016 | 0.0023 | 0.0077 |
Trichomonas vaginalis | conserved hypothetical protein | 0.004 | 0.0156 | 0.1118 |
Trypanosoma cruzi | metacaspase, putative | 0.004 | 0.0156 | 0.0525 |
Echinococcus granulosus | caspase 3 | 0.0067 | 0.0298 | 0.0725 |
Echinococcus granulosus | diuretic hormone 44 receptor GPRdih2 | 0.0016 | 0.0026 | 0.0061 |
Onchocerca volvulus | Cell death protein 3 homolog | 0.0078 | 0.0362 | 0.1158 |
Schistosoma mansoni | inositol monophosphatase | 0.0034 | 0.012 | 0.0283 |
Leishmania major | GTP-binding protein, putative | 0.0019 | 0.0042 | 0.014 |
Entamoeba histolytica | protein kinase, putative | 0.0082 | 0.0383 | 0.2298 |
Schistosoma mansoni | hypothetical protein | 0.0035 | 0.0129 | 0.0306 |
Echinococcus granulosus | histone lysine methyltransferase setb | 0.0018 | 0.0033 | 0.0079 |
Loa Loa (eye worm) | hypothetical protein | 0.004 | 0.0156 | 0.0378 |
Echinococcus granulosus | dihydrofolate reductase | 0.0767 | 0.411 | 1 |
Echinococcus multilocularis | dihydrofolate reductase | 0.0767 | 0.411 | 1 |
Echinococcus multilocularis | mitogen activated protein kinase | 0.0053 | 0.0227 | 0.0552 |
Loa Loa (eye worm) | hypothetical protein | 0.0052 | 0.0219 | 0.0531 |
Brugia malayi | GTP-binding nuclear protein RAN/TC4 | 0.0019 | 0.0042 | 0.0099 |
Trypanosoma brucei | GTP-binding nuclear protein rtb2, putative | 0.0019 | 0.0042 | 0.014 |
Trichomonas vaginalis | glucosylceramidase, putative | 0.0176 | 0.0896 | 0.6404 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0025 | 0.0074 | 0.0528 |
Brugia malayi | hypothetical protein | 0.0038 | 0.0141 | 0.0342 |
Trypanosoma brucei | metacaspase | 0.004 | 0.0156 | 0.0525 |
Trypanosoma cruzi | DNA repair protein, putative | 0.0035 | 0.0124 | 0.0417 |
Trypanosoma cruzi | ISWI complex protein | 0.0016 | 0.0023 | 0.0077 |
Toxoplasma gondii | ICE family protease (caspase) p20 domain-containing protein | 0.004 | 0.0156 | 0.0478 |
Loa Loa (eye worm) | hypothetical protein | 0.0111 | 0.0538 | 0.1307 |
Plasmodium falciparum | phd finger protein, putative | 0.003 | 0.0101 | 0.0292 |
Trichomonas vaginalis | glucosylceramidase, putative | 0.0176 | 0.0896 | 0.6404 |
Echinococcus granulosus | caspase 2 | 0.0078 | 0.0362 | 0.0879 |
Brugia malayi | latrophilin 2 splice variant baaae | 0.0035 | 0.0129 | 0.0312 |
Echinococcus granulosus | bromodomain adjacent to zinc finger domain | 0.0062 | 0.0274 | 0.0667 |
Loa Loa (eye worm) | hypothetical protein | 0.0057 | 0.0244 | 0.0591 |
Echinococcus granulosus | neuropeptide receptor A26 | 0.0485 | 0.2578 | 0.6272 |
Schistosoma mansoni | inositol monophosphatase | 0.0034 | 0.012 | 0.0283 |
Echinococcus multilocularis | GTP binding nuclear protein Ran | 0.0019 | 0.0042 | 0.0101 |
Trypanosoma cruzi | metacaspase 5, putative | 0.004 | 0.0156 | 0.0525 |
Trypanosoma cruzi | isocitrate dehydrogenase, putative | 0.0014 | 0.0015 | 0.005 |
Echinococcus multilocularis | histone lysine methyltransferase setb histone lysine methyltransferase eggless | 0.0018 | 0.0033 | 0.0079 |
Loa Loa (eye worm) | tyrosyl-DNA phosphodiesterase | 0.0069 | 0.031 | 0.0753 |
Trichomonas vaginalis | inositol monophosphatase, putative | 0.0034 | 0.012 | 0.0858 |
Echinococcus granulosus | tyrosyl DNA phosphodiesterase 1 | 0.0069 | 0.031 | 0.0754 |
Schistosoma mansoni | hypothetical protein | 0.0038 | 0.0141 | 0.0335 |
Leishmania major | metacaspase, putative | 0.004 | 0.0156 | 0.0525 |
Trypanosoma brucei | metacaspase MCA3 | 0.004 | 0.0156 | 0.0525 |
Loa Loa (eye worm) | cytochrome P450 family protein | 0.0027 | 0.0084 | 0.0202 |
Trichomonas vaginalis | conserved hypothetical protein | 0.004 | 0.0156 | 0.1118 |
Toxoplasma gondii | CMGC kinase, MAPK family (ERK) MAPK-1 | 0.0053 | 0.0227 | 0.0716 |
Entamoeba histolytica | hypothetical protein | 0.0021 | 0.0053 | 0.0315 |
Leishmania major | importin beta-1 subunit, putative | 0.0021 | 0.0053 | 0.0176 |
Echinococcus multilocularis | GPCR, family 2 | 0.0016 | 0.0026 | 0.0061 |
Trichomonas vaginalis | conserved hypothetical protein | 0.004 | 0.0156 | 0.1118 |
Schistosoma mansoni | histone-lysine n-methyltransferase setb1 | 0.0018 | 0.0033 | 0.0071 |
Echinococcus multilocularis | polycomb protein SCMH1 | 0.005 | 0.0206 | 0.0502 |
Trypanosoma cruzi | isocitrate dehydrogenase [NADP], mitochondrial precursor, putative | 0.0014 | 0.0015 | 0.005 |
Brugia malayi | Inositol-1 | 0.0034 | 0.012 | 0.029 |
Echinococcus granulosus | thymidylate synthase | 0.0213 | 0.1093 | 0.2659 |
Trypanosoma brucei | protein kinase, putative | 0.0053 | 0.0227 | 0.0762 |
Schistosoma mansoni | acetyl-CoA C-acetyltransferase | 0.0023 | 0.0064 | 0.0146 |
Schistosoma mansoni | hypothetical protein | 0.0016 | 0.0026 | 0.0053 |
Mycobacterium leprae | PROBABLE THYMIDYLATE SYNTHASE THYA (TS) (TSASE) | 0.0213 | 0.1093 | 0.2475 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0036 | 0.0131 | 0.0933 |
Trichomonas vaginalis | myo inositol monophosphatase, putative | 0.0034 | 0.012 | 0.0858 |
Loa Loa (eye worm) | O-glycosyl hydrolase family 30 protein | 0.0269 | 0.14 | 0.3403 |
Trichomonas vaginalis | myo inositol monophosphatase, putative | 0.0034 | 0.012 | 0.0858 |
Entamoeba histolytica | tyrosyl-DNA phosphodiesterase, putative | 0.0069 | 0.031 | 0.186 |
Trypanosoma brucei | tyrosyl-DNA Phosphodiesterase (Tdp1), putative | 0.0069 | 0.031 | 0.1041 |
Toxoplasma gondii | ATP-dependent DNA helicase, RecQ family protein | 0.0015 | 0.0016 | 0.0004 |
Echinococcus granulosus | histone acetyltransferase MYST2 | 0.0057 | 0.0244 | 0.0593 |
Echinococcus granulosus | lysine specific demethylase 5A | 0.0039 | 0.0147 | 0.0357 |
Trichomonas vaginalis | Clan CD, family C14, metacaspase-like cysteine peptidase | 0.004 | 0.0156 | 0.1118 |
Echinococcus granulosus | snurportin 1 | 0.0282 | 0.1469 | 0.3574 |
Trichomonas vaginalis | glucosylceramidase, putative | 0.0176 | 0.0896 | 0.6404 |
Loa Loa (eye worm) | MBCTL1 | 0.0057 | 0.0244 | 0.0591 |
Onchocerca volvulus | 0.005 | 0.0206 | 0.05 | |
Treponema pallidum | recombinase A | 0.0112 | 0.0548 | 0.5 |
Echinococcus granulosus | endonuclease exonuclease phosphatase | 0.0196 | 0.1001 | 0.2436 |
Plasmodium falciparum | bifunctional dihydrofolate reductase-thymidylate synthase | 0.0559 | 0.2981 | 1 |
Echinococcus granulosus | caspase | 0.0107 | 0.0519 | 0.1261 |
Onchocerca volvulus | Polycomb protein Sfmbt homolog | 0.005 | 0.0206 | 0.05 |
Loa Loa (eye worm) | hypothetical protein | 0.0461 | 0.2446 | 0.595 |
Brugia malayi | MAP kinase sur-1 | 0.0053 | 0.0227 | 0.055 |
Plasmodium falciparum | GTP-binding nuclear protein RAN/TC4 | 0.0019 | 0.0042 | 0.0091 |
Trichomonas vaginalis | Clan CD, family C14, metacaspase-like cysteine peptidase | 0.004 | 0.0156 | 0.1118 |
Trypanosoma brucei | mitogen activated protein kinase 4, putative | 0.0053 | 0.0227 | 0.0762 |
Trichomonas vaginalis | Clan CD, family C14, metacaspase-like cysteine peptidase | 0.004 | 0.0156 | 0.1118 |
Trichomonas vaginalis | CMGC family protein kinase | 0.0053 | 0.0227 | 0.1623 |
Echinococcus multilocularis | histone acetyltransferase MYST2 | 0.0057 | 0.0244 | 0.0593 |
Schistosoma mansoni | serine/threonine protein kinase | 0.0082 | 0.0383 | 0.0924 |
Echinococcus multilocularis | chromobox protein 1 | 0.0064 | 0.0283 | 0.0688 |
Echinococcus granulosus | cadherin EGF LAG seven pass G type receptor | 0.0016 | 0.0026 | 0.0061 |
Schistosoma mansoni | bifunctional dihydrofolate reductase-thymidylate synthase | 0.0213 | 0.1093 | 0.2653 |
Leishmania major | mitogen activated protein kinase 4, putative;with=GeneDB:LmxM19.1440 | 0.0053 | 0.0227 | 0.0762 |
Brugia malayi | mbt repeat family protein | 0.005 | 0.0206 | 0.05 |
Trichomonas vaginalis | Clan CD, family C14, metacaspase-like cysteine peptidase | 0.004 | 0.0156 | 0.1118 |
Onchocerca volvulus | Heterochromatin protein 1 homolog | 0.0036 | 0.0131 | 0.0178 |
Activity type | Activity value | Assay description | Source | Reference |
---|---|---|---|---|
Inhibition (functional) | 0 % | Percent growth inhibition of P388 mouse leukemia at 10e-8 M compound concentration in standard MTT assay; ND means No data | ChEMBL. | 11514158 |
Inhibition (functional) | = 0.7 % | Percent growth inhibition of A-549 human lung adenocarcinoma at 10e-8 M compound concentration in standard MTT assay | ChEMBL. | 11514158 |
Inhibition (functional) | = 0.7 % | Percent growth inhibition of A-549 human lung adenocarcinoma at 10e-8 M compound concentration in standard MTT assay | ChEMBL. | 11514158 |
Inhibition (functional) | = 6.7 % | Percent growth inhibition of A-549 human lung adenocarcinoma at 10e-7 M compound concentration in standard MTT assay | ChEMBL. | 11514158 |
Inhibition (functional) | = 6.7 % | Percent growth inhibition of A-549 human lung adenocarcinoma at 10e-7 M compound concentration in standard MTT assay | ChEMBL. | 11514158 |
Inhibition (functional) | = 52 % | Percent growth inhibition of P388 mouse leukemia at 10e-7 M compound concentration in standard MTT assay | ChEMBL. | 11514158 |
Inhibition (functional) | = 52 % | Percent growth inhibition of P388 mouse leukemia at 10e-7 M compound concentration in standard MTT assay | ChEMBL. | 11514158 |
Inhibition (functional) | = 80.9 % | Percent growth inhibition of A-549 human lung adenocarcinoma at 10e-6 M compound concentration in standard MTT assay | ChEMBL. | 11514158 |
Inhibition (functional) | = 80.9 % | Percent growth inhibition of A-549 human lung adenocarcinoma at 10e-6 M compound concentration in standard MTT assay | ChEMBL. | 11514158 |
Inhibition (functional) | = 90.7 % | Percent growth inhibition of P388 mouse leukemia at 10e-6 M compound concentration in standard MTT assay | ChEMBL. | 11514158 |
Inhibition (functional) | = 90.7 % | Percent growth inhibition of P388 mouse leukemia at 10e-6 M compound concentration in standard MTT assay | ChEMBL. | 11514158 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.
1 literature reference was collected for this gene.