Detailed information for compound 38156

Basic information

Technical information
  • Name: Unnamed compound
  • MW: 399.445 | Formula: C15H23N6O5S+
  • H donors: 4 H acceptors: 6 LogP: -1.75 Rotable bonds: 8
    Rule of 5 violations (Lipinski): 1
  • SMILES: CSCC[C@H](C(=O)OCC1OC(C(C1O)O)n1cnc2c1ncnc2N)[NH3+]
  • InChi: 1S/C15H22N6O5S/c1-27-3-2-7(16)15(24)25-4-8-10(22)11(23)14(26-8)21-6-20-9-12(17)18-5-19-13(9)21/h5-8,10-11,14,22-23H,2-4,16H2,1H3,(H2,17,18,19)/p+1/t7-,8?,10?,11?,14?/m0/s1
  • InChiKey: MUIFRRWPJKQRBG-KITWJDSFSA-O  

Network

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Synonyms

No synonyms found for this compound

Targets

Known targets for this compound

No curated genes were found associated with this compound

Predicted pathogen targets for this compound

By orthology
No druggable targets predicted by orthology data
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity

Obtained from network model

Ranking Plot


Putative Targets List


Species Potential target Raw Global Species
Loa Loa (eye worm) hypothetical protein 0.003 0.0136 0.015
Mycobacterium ulcerans DNA polymerase IV 0.0043 0.029 0.0266
Schistosoma mansoni 26S proteasome non-ATPase regulatory subunit 7 0.0028 0.0119 0.0112
Trypanosoma cruzi proteasome subunit beta type-2, putative 0.0176 0.1775 0.1945
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0063 0.0507 0.0507
Loa Loa (eye worm) RNA recognition domain-containing protein domain-containing protein 0.0139 0.1363 0.1494
Trichomonas vaginalis penicillin-binding protein, putative 0.0113 0.1076 0.118
Schistosoma mansoni ap endonuclease 0.0022 0.0049 0.0042
Plasmodium vivax ATP-dependent protease subunit ClpQ, putative 0.0151 0.15 0.1637
Onchocerca volvulus 0.0089 0.0805 0.2423
Plasmodium falciparum proteasome subunit beta type-5 0.0832 0.9125 1
Plasmodium falciparum heterochromatin protein 1 0.0038 0.0227 0.0241
Schistosoma mansoni zinc finger protein 0.003 0.0136 0.013
Loa Loa (eye worm) 26S proteasome regulatory complex subunit p97 0.004 0.0253 0.0277
Trichomonas vaginalis 26S protease regulatory subunit, putative 0.0019 0.0013 0.0015
Onchocerca volvulus 0.0035 0.0195 0.0569
Loa Loa (eye worm) hypothetical protein 0.0033 0.0176 0.0193
Wolbachia endosymbiont of Brugia malayi 4'-phosphopantetheinyl transferase 0.0025 0.0086 0.0258
Plasmodium falciparum proteasome subunit alpha type-1, putative 0.0181 0.1829 0.1998
Trichomonas vaginalis conserved hypothetical protein 0.0038 0.0227 0.0249
Echinococcus granulosus death domain containing protein 0.0033 0.0177 0.0178
Toxoplasma gondii proteasome subunit alpha type 1, putative 0.0181 0.1829 0.1998
Onchocerca volvulus 0.0018 0.0012 0.0014
Trichomonas vaginalis conserved hypothetical protein 0.0038 0.0227 0.0249
Trypanosoma cruzi serine peptidase, Clan SJ, family S16, putative 0.0018 0.0007 0.0008
Echinococcus multilocularis 26s proteasome regulatory particle subunit 0.004 0.0253 0.0253
Loa Loa (eye worm) transcription factor SMAD2 0.0132 0.1284 0.1407
Entamoeba histolytica hypothetical protein 0.0036 0.0204 0.0215
Trypanosoma cruzi proteasome beta 2 subunit, putative 0.0248 0.2589 0.2837
Brugia malayi proteasome subunit beta type 1 0.0201 0.206 0.2072
Brugia malayi hypothetical protein 0.0033 0.0176 0.017
Toxoplasma gondii 26S proteasome regulatory subunit 6b, putative 0.0019 0.0013 0.0006
Toxoplasma gondii heat shock protein hslv, putative 0.0151 0.15 0.1637
Trichomonas vaginalis 26S protease regulatory subunit, putative 0.0018 0.0007 0.0008
Echinococcus multilocularis beta LACTamase domain containing family member 0.0113 0.1076 0.1076
Brugia malayi proteasome subunit alpha type 1 0.0181 0.1829 0.184
Brugia malayi 20S proteasome alpha5 subunit 0.0192 0.1952 0.1964
Echinococcus multilocularis FTZ F1 nuclear receptor protein 0.0063 0.0507 0.0507
Echinococcus multilocularis Mastin 0.0035 0.0195 0.0195
Trypanosoma brucei 19S proteasome non-atpase subunit 8 0.0028 0.0119 0.013
Brugia malayi PCI domain containing protein 0.0028 0.0117 0.0111
Schistosoma mansoni tar DNA-binding protein 0.0139 0.1363 0.1369
Trichomonas vaginalis proteasome regulatory subunits, putative 0.003 0.0147 0.0161
Brugia malayi Kringle domain containing protein 0.0018 0.0012 0.0005
Loa Loa (eye worm) hypothetical protein 0.003 0.0136 0.015
Mycobacterium ulcerans fusion of enoyl-CoA hydratase, EchA21 and lipase, LipE 0.0113 0.1076 0.1132
Brugia malayi Pre-SET motif family protein 0.0033 0.0181 0.0175
Mycobacterium tuberculosis Probable dehydrogenase 0.0084 0.0741 0.0762
Entamoeba histolytica proteasome regulatory subunit, putative 0.0036 0.021 0.0222
Entamoeba histolytica proteasome subunit alpha type 5, putative 0.0192 0.1952 0.2133
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0033 0.0181 0.0175
Toxoplasma gondii 4'-phosphopantetheinyl transferase superfamily protein 0.0025 0.0086 0.0087
Brugia malayi ImpB/MucB/SamB family protein 0.0072 0.0611 0.0609
Schistosoma mansoni ecdysone-induced protein 78c (dr-78) 0.0033 0.0176 0.017
Onchocerca volvulus 0.003 0.0136 0.0392
Trypanosoma cruzi 26S proteasome regulatory non-ATPase subunit, putative 0.004 0.0253 0.0277
Echinococcus multilocularis serine:threonine protein kinase PLK1 0.0312 0.3299 0.3299
Trypanosoma brucei proteasome regulatory non-ATP-ase subunit 5 0.003 0.0147 0.0161
Schistosoma mansoni hypothetical protein 0.0054 0.0413 0.0409
Mycobacterium ulcerans 4'-phosphopantetheinyl transferase 0.0025 0.0086 0.0041
Plasmodium falciparum proteasome subunit alpha type-5, putative 0.0192 0.1952 0.2133
Leishmania major hypothetical protein, conserved 0.0045 0.0314 0.0344
Trypanosoma brucei proteasome regulatory non-ATP-ase subunit 7 0.003 0.0145 0.0159
Echinococcus multilocularis proteasome subunit alpha type 2 0.0186 0.1886 0.1886
Echinococcus multilocularis 26s protease regulatory subunit 6a 0.002 0.0026 0.0026
Entamoeba histolytica proteasome subunit alpha type 2-A, putative 0.0186 0.1886 0.206
Brugia malayi RNA binding protein 0.0139 0.1363 0.1369
Trypanosoma brucei proteasome regulatory non-ATP-ase subunit 3 0.0036 0.021 0.023
Loa Loa (eye worm) hypothetical protein 0.003 0.0136 0.015
Echinococcus multilocularis chromobox protein 1 0.023 0.2382 0.2382
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0051 0.0372 0.0368
Echinococcus granulosus thioredoxin glutathione reductase 0.0037 0.0221 0.0223
Loa Loa (eye worm) proteasome subunit alpha type 2 0.0186 0.1886 0.2067
Echinococcus granulosus 26S proteasome regulatory subunit S3 0.0036 0.021 0.0212
Echinococcus multilocularis 26S proteasome non ATPase regulatory subunit 6 0.003 0.0145 0.0145
Trypanosoma cruzi proteasome regulatory non-ATP-ase subunit 5, putative 0.003 0.0147 0.0161
Trypanosoma cruzi proteasome alpha 7 subunit, putative 0.0227 0.2344 0.2569
Brugia malayi GTP-binding regulatory protein Gs alpha-S chain, putative 0.0051 0.0372 0.0368
Mycobacterium tuberculosis Probable NADH dehydrogenase Ndh 0.0084 0.0741 0.0762
Toxoplasma gondii histone lysine methyltransferase SET/SUV39 0.0033 0.0181 0.019
Loa Loa (eye worm) hypothetical protein 0.0113 0.1076 0.118
Echinococcus multilocularis Chromo domain 0.0038 0.0227 0.0227
Schistosoma mansoni hypothetical protein 0.0035 0.0195 0.0189
Plasmodium falciparum 26S proteasome regulatory subunit p55, putative 0.003 0.0147 0.0153
Onchocerca volvulus Bile acid receptor homolog 0.0063 0.0507 0.1519
Brugia malayi Probable 26S proteasome non-ATPase regulatory subunit 6 0.003 0.0145 0.0139
Echinococcus granulosus 26S proteasome non ATPase regulatory subunit 12 0.003 0.0147 0.0148
Plasmodium vivax hypothetical protein, conserved 0.0038 0.0227 0.0241
Brugia malayi beta-lactamase family protein 0.0113 0.1076 0.1079
Mycobacterium tuberculosis Probable esterase/lipase LipP 0.0113 0.1076 0.1132
Loa Loa (eye worm) proteasome 26S subunit 0.0018 0.0007 0.0008
Trichomonas vaginalis Family T1, proteasome alpha subunit, threonine peptidase 0.0166 0.1668 0.1828
Loa Loa (eye worm) hypothetical protein 0.016 0.1602 0.1755
Toxoplasma gondii proteasome beta subunit 0.0176 0.1775 0.1938
Schistosoma mansoni 26s proteasome regulatory particle subunit 0.004 0.0253 0.0248
Echinococcus granulosus Peptidase S1 S6 chymotrypsin Hap 0.0035 0.0195 0.0197
Plasmodium falciparum 26S proteasome regulatory subunit RPN6 0.0034 0.0181 0.0191
Schistosoma mansoni DNA polymerase eta 0.0072 0.0611 0.0609
Echinococcus granulosus geminin 0.0746 0.8161 0.8234
Treponema pallidum 4'-phosphopantetheinyl transferase 0.0025 0.0086 0.0577
Schistosoma mansoni cercarial elastase (S01 family) 0.0035 0.0195 0.0189
Trichomonas vaginalis CAMK family protein kinase 0.0312 0.3299 0.3615
Trypanosoma cruzi hslVU complex proteolytic subunit, threonine peptidase, Clan T(1), family T1B 0.0151 0.15 0.1644
Schistosoma mansoni cercarial elastase (S01 family) 0.0035 0.0195 0.0189
Plasmodium falciparum proteasome subunit beta type-2, putative 0.0176 0.1775 0.1938
Brugia malayi Uncoordinated protein 44 0.0033 0.0177 0.0171
Loa Loa (eye worm) proteasome A-type and B-type family protein 0.0248 0.2589 0.2837
Echinococcus granulosus proteasome subunit beta type 7 0.0902 0.9911 1
Echinococcus granulosus DSS1 SEM1 domain containing protein 0.0081 0.071 0.0716
Plasmodium falciparum proteasome subunit beta type-4 0.0174 0.1757 0.1919
Onchocerca volvulus 0.0035 0.0195 0.0569
Loa Loa (eye worm) bifunctional aminoacyl-tRNA synthetase 0.0062 0.0498 0.0545
Echinococcus granulosus ankyrin repeat and death domain containing protein 0.0033 0.0177 0.0178
Trichomonas vaginalis CAMK family protein kinase 0.0312 0.3299 0.3615
Loa Loa (eye worm) proteasome A-type and B-type family protein 0.0174 0.1757 0.1926
Toxoplasma gondii thioredoxin reductase 0.0037 0.0215 0.0228
Trypanosoma cruzi DNA polymerase eta, putative 0.0042 0.0276 0.0303
Trypanosoma brucei Proteasome subunit A N-terminal signature/Proteasome subunit, putative 0.0181 0.1829 0.2005
Echinococcus multilocularis 26S proteasome non ATPase regulatory subunit 0.0036 0.0204 0.0204
Brugia malayi nuclear receptor NHR-88 0.003 0.0136 0.013
Loa Loa (eye worm) heterochromatin protein 1 0.023 0.2382 0.261
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0063 0.0507 0.0505
Toxoplasma gondii proteasome subunit beta type 2, putative 0.0176 0.1775 0.1938
Leishmania major proteasome alpha 5 subunit, putative,20S proteasome subunit alpha 5, (putative) 0.0192 0.1952 0.214
Onchocerca volvulus 0.003 0.0136 0.0392
Onchocerca volvulus Notchless protein homolog 0.0183 0.1851 0.5603
Trichomonas vaginalis 26S protease regulatory subunit, putative 0.002 0.0026 0.0028
Echinococcus multilocularis proteasome (prosome, macropain) subunit, beta 0.0201 0.206 0.206
Mycobacterium tuberculosis Conserved hypothetical protein 0.0043 0.029 0.0266
Schistosoma mansoni carbonic anhydrase II (carbonate dehydratase II) 0.0157 0.1563 0.1571
Loa Loa (eye worm) pre-SET domain-containing protein family protein 0.0234 0.2422 0.2654
Brugia malayi Nuclear hormone receptor family member nhr-31 0.0063 0.0507 0.0505
Echinococcus granulosus 26S protease regulatory subunit 8 0.0018 0.0007 0.0008
Echinococcus multilocularis Proteasome subunit alpha type 7 0.0227 0.2344 0.2344
Echinococcus granulosus 26S proteasome regulatory subunit T3 0.0019 0.0013 0.0013
Trypanosoma brucei proteasome regulatory non-ATP-ase subunit 2 0.0036 0.0204 0.0223
Leishmania major proteasome alpha 7 subunit, putative 0.0183 0.1851 0.2029
Trypanosoma brucei DNA polymerase kappa, putative 0.0043 0.029 0.0318
Loa Loa (eye worm) nuclear receptor NHR-67 0.003 0.0136 0.015
Mycobacterium ulcerans hypothetical protein 0.0113 0.1076 0.1132
Loa Loa (eye worm) trypsin family protein 0.0035 0.0195 0.0214
Echinococcus granulosus nuclear receptor subfamily 1 group D 0.0033 0.0176 0.0178
Echinococcus multilocularis dna polymerase eta 0.0072 0.0611 0.0611
Trypanosoma cruzi proteasome beta-1 subunit, putative 0.0182 0.1839 0.2015
Toxoplasma gondii adhesion regulating molecule region protein, putative 0.0087 0.0782 0.0849
Plasmodium vivax 26S protease regulatory subunit 4, putative 0.0019 0.0013 0.0006
Onchocerca volvulus Steroid hormone receptor family member cnr14 homolog 0.0063 0.0507 0.1519
Echinococcus granulosus histone lysine methyltransferase setb 0.0033 0.0181 0.0182
Schistosoma mansoni nuclear receptor 0.003 0.0136 0.013
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0063 0.0507 0.0505
Brugia malayi proteasome subunit alpha type 6 0.0193 0.1962 0.1974
Entamoeba histolytica exodeoxyribonuclease III, putative 0.0022 0.0049 0.0046
Leishmania major 20s proteasome beta 7 subunit, (putative) 0.0174 0.1757 0.1926
Plasmodium vivax 26S proteasome regulatory subunit RPN8, putative 0.0028 0.0119 0.0122
Schistosoma mansoni methionine-tRNA synthetase 0.008 0.0697 0.0696
Schistosoma mansoni hypothetical protein 0.0035 0.0195 0.0189
Mycobacterium tuberculosis Probable conserved lipoprotein 0.0113 0.1076 0.1132
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.003 0.0136 0.0136
Echinococcus multilocularis glycyl tRNA synthetase 0.0062 0.0498 0.0498
Schistosoma mansoni cercarial elastase (S01 family) 0.0035 0.0195 0.0189
Leishmania major trypanothione reductase 0.0037 0.0215 0.0236
Plasmodium falciparum proteasome subunit alpha type-7, putative 0.0227 0.2344 0.2563
Brugia malayi nuclear receptor subfamily 1, group D, member 1, putative 0.003 0.0136 0.013
Brugia malayi 26S proteasome regulatory subunit rpn11 0.0028 0.0119 0.0112
Schistosoma mansoni tar DNA-binding protein 0.0139 0.1363 0.1369
Trichomonas vaginalis conserved hypothetical protein 0.0038 0.0227 0.0249
Echinococcus granulosus methionyl tRNA synthetase cytoplasmic 0.008 0.0697 0.0703
Entamoeba histolytica proteasome subunit beta type 5 precursor, putative 0.0832 0.9125 1
Echinococcus granulosus 26S proteasome non ATPase regulatory subunit 4 0.002 0.0025 0.0025
Trypanosoma brucei proteasome alpha 2 subunit, putative 0.0186 0.1886 0.2067
Echinococcus granulosus carbonic anhydrase 0.0058 0.0458 0.0462
Schistosoma mansoni carbonic anhydrase-related 0.0058 0.0458 0.0455
Echinococcus multilocularis 20S proteasome subunit alpha 6 0.0181 0.1829 0.1829
Echinococcus multilocularis neuropeptide s receptor 0.0519 0.5619 0.5619
Echinococcus multilocularis 26S proteasome non ATPase regulatory subunit 8 0.0027 0.0103 0.0103
Schistosoma mansoni hypothetical protein 0.0033 0.0177 0.0171
Plasmodium falciparum AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.0022 0.0049 0.0046
Plasmodium falciparum 26S proteasome regulatory subunit RPN11, putative 0.0028 0.0119 0.0122
Schistosoma mansoni 26S proteasome regulatory subunit S3 0.0036 0.021 0.0204
Giardia lamblia DINP protein human, muc B family 0.0043 0.029 0.0318
Giardia lamblia Histone acetyltransferase GCN5 0.0044 0.0296 0.0325
Leishmania major apurinic/apyrimidinic endonuclease-redox protein 0.0022 0.0049 0.0054
Echinococcus multilocularis Chromobox protein 3 0.0038 0.0227 0.0227
Schistosoma mansoni carbonic anhydrase II (carbonate dehydratase II) 0.0157 0.1563 0.1571
Trichomonas vaginalis Family T1, proteasome alpha subunit, threonine peptidase 0.0192 0.1952 0.214
Plasmodium vivax proteasome subunit beta type-7, putative 0.0248 0.2589 0.2831
Toxoplasma gondii 26s proteasome subunit p55, putative 0.003 0.0147 0.0153
Schistosoma mansoni cercarial elastase (S01 family) 0.0035 0.0195 0.0189
Echinococcus granulosus proteasome 26s subunit subunit 4 atpase 0.0019 0.0013 0.0013
Echinococcus multilocularis FTZ F1 alpha 0.0063 0.0507 0.0507
Echinococcus granulosus DNA apurinic or apyrimidinic site lyase 0.0022 0.0049 0.005
Plasmodium vivax proteasome subunit beta type-3, putative 0.0176 0.1775 0.1938
Mycobacterium tuberculosis Proteasome beta subunit PrcB; assembles with alpha subunit PrcA. 0.0832 0.9125 1
Echinococcus multilocularis terminal deoxycytidyl transferase rev1 0.0043 0.029 0.029
Echinococcus granulosus carbonic anhydrase II 0.0157 0.1563 0.1577
Trypanosoma cruzi carbonic anhydrase-like protein, putative 0.0157 0.1563 0.1713
Loa Loa (eye worm) nuclear hormone receptor-like 1 0.0033 0.0176 0.0193
Echinococcus granulosus adhesion regulating molecule 1 0.0087 0.0782 0.0789
Plasmodium falciparum proteasome subunit beta type-1, putative 0.0201 0.206 0.2251
Echinococcus granulosus FTZ F1 nuclear receptor protein 0.0063 0.0507 0.0512
Onchocerca volvulus 0.0035 0.0195 0.0569
Trichomonas vaginalis esterase, putative 0.0113 0.1076 0.118
Trypanosoma cruzi proteasome regulatory ATPase subunit 5, putative 0.002 0.0026 0.0028
Schistosoma mansoni proteasome subunit beta 1 (T01 family) 0.0201 0.206 0.2072
Trypanosoma cruzi proteasome regulatory non-ATPase subunit, putative 0.002 0.0025 0.0028
Onchocerca volvulus 0.0038 0.0227 0.0667
Leishmania major proteasome beta 5 subunit, putative 0.0832 0.9125 1
Giardia lamblia Kinase, PLK 0.0312 0.3299 0.3615
Loa Loa (eye worm) nuclear hormone receptor family member nhr-14 0.0063 0.0507 0.0556
Echinococcus granulosus enteropeptidase 0.0035 0.0195 0.0197
Schistosoma mansoni proteasome subunit beta 2 (T01 family) 0.0176 0.1775 0.1785
Trypanosoma cruzi proteasome regulatory non-ATPase subunit 6, putative 0.0034 0.0181 0.0199
Schistosoma mansoni chromobox protein-related (chromobox 1) (heterochromatin 1) 0.0038 0.0227 0.0222
Echinococcus multilocularis proteasome 26s subunit subunit 4 atpase 0.0019 0.0013 0.0013
Trypanosoma brucei carbonic anhydrase-like protein 0.0157 0.1563 0.1713
Echinococcus multilocularis muscleblind protein 1 0.016 0.1602 0.1602
Loa Loa (eye worm) cytochrome P450 family protein 0.0055 0.0418 0.0459
Echinococcus granulosus nuclear receptor nhr 48 0.003 0.0136 0.0138
Brugia malayi ImpB/MucB/SamB family protein 0.0043 0.029 0.0286
Leishmania major 20s proteasome beta 7 subunit, (putative) 0.0174 0.1757 0.1926
Plasmodium falciparum 26S proteasome regulatory subunit RPN2, putative 0.0036 0.0204 0.0215
Brugia malayi hypothetical protein 0.0038 0.0228 0.0223
Trichomonas vaginalis bromodomain-containing protein, putative 0.0048 0.0341 0.0374
Entamoeba histolytica acetyltransferase, GNAT family 0.0044 0.0296 0.0317
Trypanosoma brucei apurinic/apyrimidinic endonuclease, putative 0.0022 0.0049 0.0054
Entamoeba histolytica hypothetical protein 0.0038 0.0228 0.0242
Loa Loa (eye worm) proteasome/cyclosome repeat family protein 0.003 0.0137 0.015
Echinococcus granulosus proteasome prosome macropain subunit alpha 0.0181 0.1834 0.1851
Loa Loa (eye worm) PCI domain-containing protein 0.0028 0.0117 0.0128
Schistosoma mansoni chromobox protein 0.0038 0.0227 0.0222
Toxoplasma gondii proteasome subunit beta type 1, putative 0.0201 0.206 0.2251
Trichomonas vaginalis Family T1, proteasome beta subunit, threonine peptidase 0.0248 0.2589 0.2837
Brugia malayi proteasome subunit alpha type 2 0.0186 0.1886 0.1897
Schistosoma mansoni subfamily S1A unassigned peptidase (S01 family) 0.0035 0.0195 0.0189
Leishmania major proteasome regulatory ATPase subunit 0.0018 0.0007 0.0008
Mycobacterium tuberculosis Possible DNA-damage-inducible protein P DinP (DNA polymerase V) (pol IV 2) (DNA nucleotidyltransferase (DNA-directed)) 0.0043 0.029 0.0266
Plasmodium falciparum glutathione reductase 0.0037 0.0215 0.0228
Schistosoma mansoni cercarial elastase (S01 family) 0.0035 0.0195 0.0189
Echinococcus multilocularis proteasome (prosome, macropain) 0.0832 0.9125 0.9125
Trypanosoma brucei proteasome alpha 7 subunit, putative 0.0227 0.2344 0.2569
Plasmodium falciparum proteasome subunit alpha type-3, putative 0.0183 0.1851 0.2022
Echinococcus granulosus nuclear receptor subfamily 4 group A 0.003 0.0136 0.0138
Echinococcus granulosus proteasome prosome macropain subunit beta 0.0201 0.206 0.2078
Toxoplasma gondii Proteasome/cyclosome repeat-containing protein 0.0036 0.0204 0.0215
Plasmodium vivax proteasome subunit alpha type-6, putative 0.0193 0.1962 0.2144
Leishmania major proteasome regulatory non-ATPase subunit, putative 0.004 0.0253 0.0277
Trichomonas vaginalis D-aminoacylase, putative 0.0113 0.1076 0.118
Onchocerca volvulus Proteasomal ubiquitin receptor ADRM1 homolog 0.0055 0.0425 0.1269
Loa Loa (eye worm) hypothetical protein 0.0063 0.0507 0.0556
Mycobacterium tuberculosis Probable reductase 0.0084 0.0741 0.0762
Loa Loa (eye worm) helicase 0.0038 0.0227 0.0249
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0063 0.0507 0.0505
Loa Loa (eye worm) acetyltransferase 0.0163 0.1627 0.1784
Echinococcus granulosus proteasome prosome macropain subunit beta type 0.0174 0.1757 0.1773
Trichomonas vaginalis conserved hypothetical protein 0.0038 0.0227 0.0249
Plasmodium falciparum 26S proteasome regulatory subunit RPN7, putative 0.003 0.0145 0.0151
Echinococcus granulosus Mastin 0.0035 0.0195 0.0197
Trichomonas vaginalis Family T1, proteasome alpha subunit, threonine peptidase 0.0171 0.1718 0.1883
Plasmodium vivax histone acetyltransferase GCN5, putative 0.0048 0.0341 0.0366
Toxoplasma gondii ImpB/MucB/SamB family protein 0.0042 0.0276 0.0295
Onchocerca volvulus 0.0035 0.0195 0.0569
Echinococcus granulosus Proteasome subunit alpha type 7 0.0227 0.2344 0.2365
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0038 0.0227 0.0249
Schistosoma mansoni cercarial elastase (S01 family) 0.0035 0.0195 0.0189
Trypanosoma cruzi DNA polymerase eta, putative 0.0072 0.0611 0.0669
Schistosoma mansoni 26S protease regulatory subunit 6a 0.002 0.0026 0.0019
Mycobacterium ulcerans beta-lactamase 0.0113 0.1076 0.1132
Leishmania major carbonic anhydrase-like protein 0.0157 0.1563 0.1713
Brugia malayi proteasome subunit beta type 2 0.0176 0.1775 0.1785
Schistosoma mansoni cercarial elastase (S01 family) 0.0035 0.0195 0.0189
Toxoplasma gondii hypothetical protein 0.0058 0.0458 0.0494
Echinococcus multilocularis Nuclear hormone receptor HR96 0.003 0.0136 0.0136
Brugia malayi Eukaryotic-type carbonic anhydrase family protein 0.0058 0.0458 0.0455
Brugia malayi 26S proteasome non-ATPase regulatory subunit Nin1/mts3 family protein 0.0027 0.0103 0.0096
Mycobacterium ulcerans proteasome PrcA 0.0151 0.15 0.1599
Schistosoma mansoni coup transcription factor 0.0063 0.0507 0.0505
Loa Loa (eye worm) proteasome regulatory particle 0.0034 0.0181 0.0199
Trypanosoma brucei DNA polymerase kappa, putative 0.0043 0.029 0.0318
Mycobacterium tuberculosis NAD(P)H quinone reductase LpdA 0.0093 0.0845 0.0877
Leishmania major proteasome alpha 1 subunit, putative 0.0193 0.1962 0.215
Brugia malayi Nuclear hormone receptor family member nhr-40 0.0063 0.0507 0.0505
Loa Loa (eye worm) hypothetical protein 0.0033 0.0181 0.0198
Leishmania major 20s proteasome beta 7 subunit, (putative) 0.0174 0.1757 0.1926
Schistosoma mansoni subfamily T1A non-peptidase homologue (T01 family) 0.0192 0.1952 0.1964
Loa Loa (eye worm) glycyl-tRNA synthetase 0.0062 0.0498 0.0545
Trypanosoma cruzi proteasome alpha 7 subunit, putative 0.0183 0.1851 0.2029
Entamoeba histolytica deoxycytidyl transferase, putative 0.0043 0.029 0.031
Echinococcus multilocularis Peptidase S1 S6, chymotrypsin Hap 0.0035 0.0195 0.0195
Mycobacterium leprae DIHYDROLIPOAMIDE DEHYDROGENASE LPD (LIPOAMIDE REDUCTASE (NADH)) (LIPOYL DEHYDROGENASE) (DIHYDROLIPOYL DEHYDROGENASE) (DIAPHORASE 0.0093 0.0845 0.084
Trypanosoma brucei proteasome beta-1 subunit, putative 0.0182 0.1839 0.2015
Trichomonas vaginalis Family T1, proteasome beta subunit, threonine peptidase 0.0176 0.1775 0.1945
Loa Loa (eye worm) hypothetical protein 0.0019 0.0013 0.0015
Echinococcus multilocularis adhesion regulating molecule 1 0.0087 0.0782 0.0782
Mycobacterium leprae probable proteasome (alpha subunit) PrcA 0.0151 0.15 0.1564
Trypanosoma cruzi proteasome alpha 2 subunit, putative 0.0186 0.1886 0.2067
Schistosoma mansoni nuclear hormone receptor superfamily protein-related 0.003 0.0136 0.013
Trypanosoma cruzi hypothetical protein, conserved 0.0113 0.1076 0.118
Loa Loa (eye worm) hypothetical protein 0.0113 0.1076 0.118
Brugia malayi proteasome subunit alpha type 4 0.0166 0.1666 0.1675
Trichomonas vaginalis ap endonuclease, putative 0.0022 0.0049 0.0054
Plasmodium falciparum thioredoxin reductase 0.0037 0.0215 0.0228
Schistosoma mansoni nuclear hormone receptor 0.003 0.0136 0.013
Trypanosoma cruzi proteasome regulatory non-ATP-ase subunit 9, putative 0.0028 0.0117 0.0128
Trypanosoma brucei proteasome beta 7 subunit 0.0174 0.1757 0.1926
Brugia malayi MH2 domain containing protein 0.0132 0.1284 0.1289
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0113 0.1076 0.1079
Trichomonas vaginalis CAMK family protein kinase 0.0312 0.3299 0.3615
Toxoplasma gondii SAC3/GANP family protein 0.0027 0.0103 0.0105
Schistosoma mansoni kinase 0.0158 0.1581 0.1589
Trypanosoma brucei proteasome regulatory non-ATP-ase subunit 9 0.0028 0.0117 0.0128
Mycobacterium tuberculosis Dihydrolipoamide dehydrogenase LpdC (lipoamide reductase (NADH)) (lipoyl dehydrogenase) (dihydrolipoyl dehydrogenase) (diaphoras 0.0093 0.0845 0.0877
Trichomonas vaginalis 26S proteasome subunit S9, putative 0.0034 0.0181 0.0199
Schistosoma mansoni cercarial elastase (S01 family) 0.0035 0.0195 0.0189
Echinococcus multilocularis Basic leucine zipper (bZIP) transcription 0.0038 0.0228 0.0228
Brugia malayi Carbonic anhydrase like protein 2 precursor 0.0058 0.0458 0.0455
Echinococcus multilocularis retinoic acid receptor rxr beta a retinoic acid receptor rxr alpha a retinoic acid receptor rxr alpha 0.003 0.0136 0.0136
Trypanosoma cruzi apurinic/apyrimidinic endonuclease 0.0022 0.0049 0.0054
Entamoeba histolytica proteasome regulatory subunit, putative 0.003 0.0147 0.0153
Schistosoma mansoni cercarial elastase (S01 family) 0.0035 0.0195 0.0189
Entamoeba histolytica 26S proteasome non-ATPase regulatory subunit 14, putative 0.0028 0.0119 0.0122
Brugia malayi Steroid receptor seven-up type 2 0.0063 0.0507 0.0505
Echinococcus granulosus 26S proteasome non ATPase regulatory subunit 8 0.0027 0.0103 0.0104
Trichomonas vaginalis cat eye syndrome critical region protein 2, cscr2, putative 0.0048 0.0341 0.0374
Schistosoma mansoni chromodomain helicase DNA binding protein 0.0038 0.0227 0.0222
Entamoeba histolytica proteasome subunit alpha type 7, putative 0.0227 0.2344 0.2563
Trypanosoma cruzi proteasome regulatory ATPase subunit 3, putative 0.0019 0.0013 0.0015
Trichomonas vaginalis 26S proteasome regulatory subunit, putative 0.003 0.0137 0.015
Plasmodium falciparum cysteine repeat modular protein 1 0.0018 0.0012 0.0005
Loa Loa (eye worm) hypothetical protein 0.0063 0.0507 0.0556
Trypanosoma brucei proteasome regulatory ATPase subunit 2 0.0019 0.0013 0.0015
Loa Loa (eye worm) hypothetical protein 0.0035 0.0195 0.0214
Plasmodium vivax proteasome subunit alpha type-3, putative 0.0183 0.1851 0.2022
Mycobacterium tuberculosis Probable oxidoreductase 0.0093 0.0845 0.0877
Trypanosoma cruzi polo-like protein kinase, putative 0.0312 0.3299 0.3615
Echinococcus multilocularis thioredoxin glutathione reductase 0.0037 0.0221 0.0221
Trichomonas vaginalis Family T1, proteasome alpha subunit, threonine peptidase 0.0193 0.1962 0.215
Echinococcus multilocularis 26S proteasome regulatory subunit T3 0.0019 0.0013 0.0013
Plasmodium vivax 26S proteasome regulatory subunit RPN11, putative 0.0028 0.0119 0.0122
Loa Loa (eye worm) hypothetical protein 0.0113 0.1076 0.118
Trichomonas vaginalis Family T1, proteasome alpha subunit, threonine peptidase 0.0183 0.1851 0.2029
Schistosoma mansoni 26S protease regulatory subunit 0.0019 0.0013 0.0006
Echinococcus granulosus carbonic anhydrase 0.0058 0.0458 0.0462
Schistosoma mansoni cercarial elastase (S01 family) 0.0035 0.0195 0.0189
Loa Loa (eye worm) hypothetical protein 0.0101 0.0938 0.1027
Loa Loa (eye worm) hypothetical protein 0.0018 0.0012 0.0013
Trichomonas vaginalis 26S proteasome regulatory subunit S3, putative 0.002 0.0025 0.0028
Echinococcus multilocularis chromodomain helicase DNA binding protein 1 0.0038 0.0227 0.0227
Loa Loa (eye worm) proteasome subunit alpha type 7-1 0.0227 0.2344 0.2569
Trypanosoma brucei proteasome alpha 3 subunit, putative 0.0181 0.1834 0.201
Trichomonas vaginalis Family T1, proteasome beta subunit, threonine peptidase 0.0832 0.9125 1
Schistosoma mansoni subfamily T1A non-peptidase homologue (T01 family) 0.0192 0.1952 0.1964
Trichomonas vaginalis conserved hypothetical protein 0.0038 0.0227 0.0249
Trypanosoma cruzi trypanothione reductase, putative 0.0037 0.0215 0.0236
Plasmodium falciparum 26S protease regulatory subunit 6A, putative 0.002 0.0026 0.002
Loa Loa (eye worm) hypothetical protein 0.003 0.0136 0.015
Entamoeba histolytica proteasome subunit alpha type 3, putative 0.0183 0.1851 0.2022
Trichomonas vaginalis chromobox protein, putative 0.0038 0.0227 0.0249
Trypanosoma brucei proteasome beta 2 subunit, putative 0.0248 0.2589 0.2837
Echinococcus multilocularis Nuclear hormone receptor family member nhr 41 0.0063 0.0507 0.0507
Trichomonas vaginalis 26S protease regulatory subunit S10b, putative 0.0018 0.0007 0.0008
Schistosoma mansoni photoreceptor-specific nuclear receptor related 0.0063 0.0507 0.0505
Brugia malayi beta-lactamase family protein 0.0113 0.1076 0.1079
Entamoeba histolytica proteasome subunit beta type 6 precursor, putative 0.0182 0.1839 0.2009
Trichomonas vaginalis DNA polymerase IV / kappa, putative 0.0043 0.029 0.0318
Toxoplasma gondii 26S protease regulatory subunit 4, putative 0.0019 0.0013 0.0006
Plasmodium vivax 26S proteasome regulatory subunit RPN12, putative 0.0027 0.0103 0.0105
Loa Loa (eye worm) TK/ROR protein kinase 0.0018 0.0012 0.0013
Leishmania major proteasome beta 2 subunit, putative 0.0248 0.2589 0.2837
Giardia lamblia Proteasome subunit beta type 9 precursor 0.0182 0.1839 0.2015
Trypanosoma brucei DNA polymerase kappa, putative 0.003 0.014 0.0153
Echinococcus granulosus 26s protease regulatory subunit s10b 0.0018 0.0007 0.0008
Brugia malayi acetyltransferase, GNAT family protein 0.0163 0.1627 0.1636
Echinococcus granulosus carbonic anhydrase 0.0058 0.0458 0.0462
Trichomonas vaginalis chromobox protein, putative 0.0139 0.1359 0.149
Trichomonas vaginalis CAMK family protein kinase 0.0312 0.3299 0.3615
Trypanosoma cruzi proteasome subunit alpha type-5, putative 0.0192 0.1952 0.214
Loa Loa (eye worm) proteasome Regulatory Particle 0.003 0.0145 0.0159
Echinococcus multilocularis histone lysine methyltransferase setb histone lysine methyltransferase eggless 0.0033 0.0181 0.0181
Mycobacterium tuberculosis Probable lipase LipE 0.0113 0.1076 0.1132
Echinococcus granulosus proteasome subunit alpha type 6 0.0193 0.1962 0.198
Schistosoma mansoni proteasome regulatory subunit-related 0.003 0.0147 0.014
Echinococcus multilocularis carbonic anhydrase 0.0058 0.0458 0.0458
Mycobacterium leprae conserved hypothetical protein 0.0113 0.1076 0.1095
Brugia malayi steroid hormone receptor 0.0063 0.0507 0.0505
Echinococcus multilocularis proteasome subunit beta type 7 0.0902 0.9911 0.9911
Giardia lamblia 20S proteasome alpha subunit 7 0.0183 0.1851 0.2029
Echinococcus multilocularis tissue type plasminogen activator 0.0018 0.0012 0.0012
Entamoeba histolytica hypothetical protein 0.0038 0.0227 0.0241
Brugia malayi Associated with TFs and helicases family protein 0.0038 0.0227 0.0222
Treponema pallidum methionyl-tRNA synthetase 0.008 0.0697 1
Trichomonas vaginalis 26S proteasome subunit, putative 0.0028 0.0117 0.0128
Loa Loa (eye worm) hypothetical protein 0.0063 0.0507 0.0556
Trichomonas vaginalis Family T1, proteasome beta subunit, threonine peptidase 0.0176 0.1775 0.1945
Giardia lamblia Hypothetical protein 0.0034 0.0181 0.0199
Echinococcus granulosus 26S proteasome regulatory subunit N11 0.0028 0.0119 0.012
Loa Loa (eye worm) hypothetical protein 0.008 0.0697 0.0764
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0051 0.0372 0.0372
Trichomonas vaginalis conserved hypothetical protein 0.0091 0.0828 0.0907
Echinococcus granulosus chromobox protein 2 0.0038 0.0227 0.0229
Plasmodium falciparum proteasome subunit alpha type-4, putative 0.0181 0.1834 0.2004
Loa Loa (eye worm) hypothetical protein 0.0035 0.0195 0.0214
Schistosoma mansoni hypothetical protein 0.0038 0.0228 0.0222
Plasmodium vivax 26S proteasome regulatory subunit RPN6, putative 0.0034 0.0181 0.0191
Brugia malayi proteasome subunit beta type 3 0.0176 0.1775 0.1785
Toxoplasma gondii proteasome subunit 0.0182 0.1839 0.2009
Trichomonas vaginalis conserved hypothetical protein 0.0038 0.0227 0.0249
Trypanosoma cruzi DNA polymerase kappa, putative 0.0043 0.029 0.0318
Echinococcus multilocularis nuclear receptor nhr 48 0.003 0.0136 0.0136
Giardia lamblia 20S proteasome alpha subunit 4 0.0227 0.2344 0.2569
Trypanosoma cruzi proteasome regulatory non-ATP-ase subunit 7, putative 0.0027 0.0108 0.0119
Schistosoma mansoni hepatocyte nuclear factor 4-alpha (hnf-4-alpha) 0.003 0.0136 0.013
Giardia lamblia 26S proteasome non-ATPase regulatory subunit 6 0.003 0.0145 0.0159
Giardia lamblia 26S proteasome ATPase subunit S4, putative 0.0019 0.0013 0.0015
Entamoeba histolytica proteasome subunit alpha type 3, putative 0.0183 0.1851 0.2022
Trypanosoma brucei DNA polymerase IV, putative 0.0043 0.029 0.0318
Mycobacterium ulcerans lipase LipD 0.0113 0.1076 0.1132
Plasmodium vivax proteasome subunit alpha type-5, putative 0.0192 0.1952 0.2133
Giardia lamblia Endonuclease/Exonuclease/phosphatase 0.0022 0.0049 0.0054
Echinococcus granulosus glycyl tRNA synthetase 0.0062 0.0498 0.0502
Chlamydia trachomatis methionine--tRNA ligase 0.008 0.0697 1
Brugia malayi RNA recognition motif domain containing protein 0.0139 0.1363 0.1369
Brugia malayi Cytochrome P450 family protein 0.0055 0.0418 0.0415
Loa Loa (eye worm) 26S proteasome regulatory subunit rpn11 0.0028 0.0119 0.013
Brugia malayi Carbonic anhydrase like protein 2 precursor 0.0058 0.0458 0.0455
Schistosoma mansoni chromobox protein 0.023 0.2382 0.2398
Brugia malayi glutathione reductase 0.0037 0.0215 0.021
Schistosoma mansoni chromobox protein-related (chromobox 1) (heterochromatin 1) 0.0038 0.0227 0.0222
Trypanosoma cruzi proteasome alpha 7 subunit, putative 0.0227 0.2344 0.2569
Trypanosoma brucei unspecified product 0.0043 0.029 0.0318
Plasmodium vivax hypothetical protein, conserved 0.0113 0.1076 0.1172
Loa Loa (eye worm) nuclear hormone receptor family member nhr-40 0.0063 0.0507 0.0556
Echinococcus multilocularis transmembrane protease serine 3 0.0035 0.0195 0.0195
Brugia malayi 26S proteasome non-ATPase regulatory subunit Nin1/mts3 family protein 0.0027 0.0103 0.0096
Trypanosoma cruzi 26S proteasome regulatory non-ATPase subunit, putative 0.0019 0.0019 0.0021
Mycobacterium ulcerans phosphopantetheinyl transferase, PptII 0.0025 0.0086 0.0041
Entamoeba histolytica proteasome subunit beta type 7-B precursor, putative 0.0248 0.2589 0.2831
Loa Loa (eye worm) hypothetical protein 0.0038 0.0227 0.0249
Loa Loa (eye worm) hypothetical protein 0.0606 0.659 0.7222
Echinococcus multilocularis Proteasome subunit alpha type 7 0.0227 0.2344 0.2344
Onchocerca volvulus 0.0113 0.1076 0.3248
Brugia malayi Chymotrypsin-like protease CTRL-1 precursor 0.0035 0.0195 0.0189
Echinococcus multilocularis 26S proteasome non ATPase regulatory subunit 12 0.003 0.0147 0.0147
Plasmodium falciparum chromodomain-helicase-DNA-binding protein 1 homolog, putative 0.0038 0.0227 0.0241
Toxoplasma gondii 26s proteasome regulatory complex subunit, putative 0.003 0.0145 0.0151
Leishmania major proteasome beta 2 subunit, putative 0.0176 0.1775 0.1945
Echinococcus multilocularis proteasome subunit alpha type 6 0.0193 0.1962 0.1962
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0038 0.0227 0.0249
Echinococcus multilocularis Nuclear hormone receptor HR96 0.003 0.0136 0.0136
Loa Loa (eye worm) proteasome subunit alpha type 3 0.0183 0.1851 0.2029
Brugia malayi 26S proteasome regulatory complex subunit p97 0.004 0.0253 0.0248
Brugia malayi hypothetical protein 0.003 0.0136 0.013
Onchocerca volvulus Nuclear receptor subfamily 6 group A member 1 homolog 0.003 0.0136 0.0392
Entamoeba histolytica hypothetical protein 0.0038 0.0227 0.0241
Schistosoma mansoni 26S proteasome non-ATPase regulatory subunit 0.0027 0.0103 0.0096
Schistosoma mansoni carbonic anhydrase 0.0058 0.0458 0.0455
Schistosoma mansoni chromodomain helicase DNA binding protein 0.0038 0.0227 0.0222
Brugia malayi Valyl-tRNA synthetase 0.0038 0.0227 0.0222
Trypanosoma brucei ATP-dependent protease subunit HslV 0.0151 0.15 0.1644
Echinococcus multilocularis L aminoadipate semialdehyde 0.0089 0.0805 0.0805
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0038 0.0227 0.0249
Plasmodium vivax SET domain protein, putative 0.0033 0.0181 0.019
Trichomonas vaginalis regulatory particle non-ATPase, putative 0.0028 0.0117 0.0128
Toxoplasma gondii histone lysine acetyltransferase GCN5-B 0.0048 0.0341 0.0366
Echinococcus granulosus proteasome subunit beta type 6 0.0182 0.1839 0.1856
Trypanosoma cruzi proteasome beta 7 subunit, putative 0.0174 0.1757 0.1926
Echinococcus granulosus 20S proteasome subunit alpha 6 0.0181 0.1829 0.1846
Echinococcus multilocularis proteasome subunit beta type 6 0.0182 0.1839 0.1839
Brugia malayi Muscleblind-like protein 0.016 0.1602 0.161
Plasmodium vivax proteasome subunit alpha type-1, putative 0.0181 0.1829 0.1998
Echinococcus granulosus transmembrane protease serine 3 0.0035 0.0195 0.0197
Trypanosoma cruzi apurinic/apyrimidinic endonuclease, putative 0.0022 0.0049 0.0054
Giardia lamblia Proteasome subunit beta type 2 0.0176 0.1775 0.1945
Plasmodium vivax 26S proteasome regulatory subunit RPN2, putative 0.0036 0.0204 0.0215
Leishmania major proteasome regulatory non-ATP-ase subunit, putative 0.003 0.0145 0.0159
Echinococcus granulosus 26s proteasome regulatory particle subunit 0.004 0.0253 0.0255
Echinococcus multilocularis nuclear receptor subfamily 1 group D 0.0033 0.0176 0.0176
Trypanosoma brucei DNA polymerase kappa, putative 0.0043 0.029 0.0318
Loa Loa (eye worm) beta-lactamase 0.0113 0.1076 0.118
Trypanosoma brucei unspecified product 0.003 0.014 0.0153
Schistosoma mansoni cercarial elastase (S01 family) 0.0035 0.0195 0.0189
Brugia malayi Probable 26S protease regulatory subunit 4 0.0019 0.0013 0.0006
Brugia malayi hypothetical protein 0.0033 0.0176 0.017
Loa Loa (eye worm) hypothetical protein 0.0027 0.0103 0.0113
Loa Loa (eye worm) hypothetical protein 0.0035 0.0195 0.0214
Loa Loa (eye worm) hypothetical protein 0.0063 0.0507 0.0556
Loa Loa (eye worm) hypothetical protein 0.0113 0.1076 0.118
Brugia malayi Nuclear hormone receptor family member nhr-1 0.0063 0.0507 0.0505
Echinococcus granulosus terminal deoxycytidyl transferase rev1 0.0043 0.029 0.0293
Trypanosoma brucei hypothetical protein, conserved 0.0113 0.1076 0.118
Echinococcus multilocularis hepatocyte nuclear factor 4 alpha 0.0063 0.0507 0.0507
Toxoplasma gondii proteasome subunit beta type, putative 0.0832 0.9125 1
Echinococcus granulosus Nuclear hormone receptor HR96 0.003 0.0136 0.0138
Trypanosoma brucei polo-like protein kinase 0.0312 0.3299 0.3615
Onchocerca volvulus Heterochromatin protein 1 homolog 0.0129 0.125 0.3774
Loa Loa (eye worm) PLK/PLK1 protein kinase 0.0312 0.3299 0.3615
Loa Loa (eye worm) hypothetical protein 0.0038 0.0227 0.0249
Trichomonas vaginalis 26S proteasome non-ATPase regulatory subunit, putative 0.0027 0.0103 0.0113
Trypanosoma brucei proteasome alpha 7 subunit 0.0183 0.1851 0.2029
Loa Loa (eye worm) hypothetical protein 0.0089 0.0805 0.0882
Trypanosoma cruzi proteasome subunit beta type-5, putative 0.0832 0.9125 1
Brugia malayi 26S protease regulatory subunit 6A 0.002 0.0026 0.0019
Echinococcus granulosus neuropeptide s receptor 0.0519 0.5619 0.567
Loa Loa (eye worm) hypothetical protein 0.0033 0.0176 0.0193
Loa Loa (eye worm) eukaryotic-type carbonic anhydrase 0.0058 0.0458 0.0502
Toxoplasma gondii hypothetical protein 0.0025 0.008 0.0079
Trichomonas vaginalis ap endonuclease, putative 0.0022 0.0049 0.0054
Loa Loa (eye worm) nuclear hormone receptor family member nhr-1 0.0063 0.0507 0.0556
Trypanosoma cruzi hypothetical protein, conserved 0.0113 0.1076 0.118
Leishmania major proteasome alpha 3 subunit, putative 0.0181 0.1834 0.201
Entamoeba histolytica proteasome subunit alpha type 5, putative 0.0192 0.1952 0.2133
Trypanosoma brucei protease regulatory ATPase subunit 4 0.0018 0.0007 0.0008
Schistosoma mansoni 26s proteasome regulatory particle subunit 0.004 0.0253 0.0248
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0038 0.0227 0.0249
Plasmodium falciparum 26S proteasome regulatory subunit RPN1, putative 0.004 0.0253 0.0269
Loa Loa (eye worm) 20S proteasome alpha5 subunit 0.0192 0.1952 0.214
Echinococcus multilocularis chromobox protein 2 0.0038 0.0227 0.0227
Brugia malayi methionyl-tRNA synthetase 0.008 0.0697 0.0696
Schistosoma mansoni 26S proteasome regulatory subunit S3 0.0036 0.021 0.0204
Plasmodium vivax 26S proteasome regulatory subunit RPN1, putative 0.004 0.0253 0.0269
Trichomonas vaginalis 26S proteasome regulatory subunit, putative 0.004 0.0253 0.0277
Toxoplasma gondii proteasome 26S regulatory subunit 0.0019 0.0019 0.0013
Trypanosoma brucei DNA polymerase kappa, putative 0.0043 0.029 0.0318
Schistosoma mansoni proteasome subunit alpha 3 (T01 family) 0.0183 0.1851 0.1862
Onchocerca volvulus Nuclear receptor subfamily 6 group A member 1 homolog 0.003 0.0136 0.0392
Echinococcus multilocularis 26S proteasome regulatory subunit N1 0.0028 0.0117 0.0117
Loa Loa (eye worm) hypothetical protein 0.0038 0.0227 0.0249
Trichomonas vaginalis hypothetical protein 0.0038 0.0227 0.0249
Toxoplasma gondii proteasome subunit alpha type 5-2, putative 0.0192 0.1952 0.2133
Trichomonas vaginalis DNA polymerase eta, putative 0.0043 0.029 0.0318
Onchocerca volvulus 0.0266 0.2785 0.8439
Trypanosoma cruzi 19S proteasome non-atpase subunit 8 0.0028 0.0119 0.013
Echinococcus granulosus nuclear factor of activated T cells 5 0.0324 0.3438 0.3469
Plasmodium vivax proteasome subunit beta type-5, putative 0.0832 0.9125 1
Brugia malayi Nuclear hormone receptor E75 0.003 0.0136 0.013
Giardia lamblia 20S proteasome alpha subunit 6 0.0181 0.1829 0.2005
Entamoeba histolytica proteasome subunit beta type 1, putative 0.0201 0.206 0.2251
Loa Loa (eye worm) steroid hormone receptor 0.0063 0.0507 0.0556
Loa Loa (eye worm) hypothetical protein 0.003 0.0136 0.015
Toxoplasma gondii PCI domain-containing protein 0.0028 0.0117 0.012
Trypanosoma brucei DNA polymerase eta, putative 0.0072 0.0611 0.0669
Loa Loa (eye worm) thioredoxin reductase 0.0037 0.0215 0.0236
Trichomonas vaginalis Heterochromatin protein, putative 0.0038 0.0227 0.0249
Schistosoma mansoni chromobox protein 0.0038 0.0227 0.0222
Trichomonas vaginalis conserved hypothetical protein 0.0038 0.0227 0.0249
Loa Loa (eye worm) hypothetical protein 0.0035 0.0195 0.0214
Loa Loa (eye worm) hypothetical protein 0.003 0.0136 0.015
Echinococcus granulosus 26S proteasome regulatory subunit N1 0.0028 0.0117 0.0118
Brugia malayi Proteasome A-type and B-type family protein 0.0182 0.1839 0.1849
Loa Loa (eye worm) hypothetical protein 0.0033 0.0178 0.0195
Giardia lamblia 20S proteasome alpha subunit 5 0.0192 0.1952 0.214
Trichomonas vaginalis Family T1, proteasome alpha subunit, threonine peptidase 0.0227 0.2344 0.2569
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0063 0.0507 0.0512
Brugia malayi Nuclear hormone receptor-like 1 0.0033 0.0176 0.017
Echinococcus multilocularis carbonic anhydrase 0.0058 0.0458 0.0458
Schistosoma mansoni 26s proteasome regulatory particle subunit 0.004 0.0253 0.0248
Wolbachia endosymbiont of Brugia malayi ATP-dependent protease peptidase subunit 0.0151 0.15 1
Trichomonas vaginalis conserved hypothetical protein 0.0038 0.0227 0.0249
Brugia malayi Probable 26S proteasome non-ATPase regulatory subunit 3 0.0036 0.021 0.0204
Echinococcus multilocularis histone lysine N methyltransferase SETMAR 0.0033 0.0181 0.0181
Loa Loa (eye worm) hypothetical protein 0.0019 0.0013 0.0015
Loa Loa (eye worm) immunoglobulin I-set domain-containing protein 0.0033 0.0177 0.0194
Plasmodium vivax cysteine repeat modular protein 1, putative 0.0018 0.0012 0.0005
Brugia malayi Proteasome subunit alpha type 7-1 0.0227 0.2344 0.236
Trypanosoma cruzi proteasome regulatory ATPase subunit 3, putative 0.0019 0.0013 0.0015
Mycobacterium tuberculosis Putative ferredoxin reductase 0.0084 0.0741 0.0762
Plasmodium falciparum 26S proteasome regulatory subunit RPN13, putative 0.0045 0.0314 0.0336
Schistosoma mansoni retinoblastoma-binding protein 4 (rbbp4) 0.0033 0.0178 0.0172
Brugia malayi Hypothetical 35.8 kDa protein F37A4.5 in chromosome III 0.0028 0.0119 0.0112
Loa Loa (eye worm) hypothetical protein 0.003 0.0136 0.015
Mycobacterium tuberculosis Conserved protein 0.0113 0.1076 0.1132
Echinococcus multilocularis nuclear factor of activated T cells 5 0.0324 0.3438 0.3438
Schistosoma mansoni proteasome subunit alpha 6 (T01 family) 0.0193 0.1962 0.1974
Onchocerca volvulus 0.0063 0.0507 0.1519
Entamoeba histolytica proteasome subunit alpha type 1, putative 0.0181 0.1829 0.1998
Loa Loa (eye worm) CHromoDomain protein family member 0.0038 0.0227 0.0249
Loa Loa (eye worm) nuclear Hormone Receptor family member 0.0063 0.0507 0.0556
Giardia lamblia 20S proteasome alpha subunit 2 0.0186 0.1886 0.2067
Brugia malayi Proteasome A-type and B-type family protein 0.0832 0.9125 0.9206
Toxoplasma gondii proteasome subunit alpha type, putative 0.0075 0.0649 0.0704
Onchocerca volvulus Netrin receptor homolog 0.0033 0.0177 0.0514
Brugia malayi small heat shock protein 0.0606 0.659 0.6647
Onchocerca volvulus Serine\/threonine kinase homolog 0.0312 0.3299 1
Brugia malayi aminoadipate-semialdehyde dehydrogenase-phosphopantetheinyl transferase 0.0089 0.0805 0.0805
Entamoeba histolytica proteasome subunit alpha type 7, putative 0.0227 0.2344 0.2563
Mycobacterium tuberculosis Probable membrane NADH dehydrogenase NdhA 0.0084 0.0741 0.0762
Onchocerca volvulus Heterochromatin protein 1 homolog 0.0139 0.1359 0.4107
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0038 0.0227 0.0249
Plasmodium vivax thioredoxin reductase, putative 0.0037 0.0215 0.0228
Echinococcus granulosus chromodomain helicase DNA binding protein 1 0.0038 0.0227 0.0229
Trypanosoma brucei proteasome regulatory non-ATP-ase subunit 0.0027 0.0103 0.0113
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0051 0.0372 0.0375
Leishmania major proteasome regulatory non-ATP-ase subunit 8, putative,26S proteasome regulatory subunit, putative 0.0028 0.0119 0.013
Trypanosoma brucei proteasome alpha 1 subunit, putative 0.0193 0.1962 0.215
Leishmania major protein kinase, putative,polo-like protein kinase, putative 0.0312 0.3299 0.3615
Brugia malayi Pre-SET motif family protein 0.0234 0.2422 0.2438
Loa Loa (eye worm) nuclear hormone receptor family member nhr-49 0.0063 0.0507 0.0556
Trichomonas vaginalis conserved hypothetical protein 0.0129 0.125 0.1369
Leishmania major proteasome regulatory ATPase subunittcc1l8.3, putative 0.0019 0.0013 0.0015
Brugia malayi proteasome subunit alpha type 3 0.0183 0.1851 0.1862
Brugia malayi 26S proteasome subunit P45 family protein 0.0019 0.0013 0.0006
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0113 0.1076 0.1079
Brugia malayi photoreceptor-specific nuclear receptor 0.0063 0.0507 0.0505
Loa Loa (eye worm) hypothetical protein 0.0063 0.0507 0.0556
Schistosoma mansoni hypothetical protein 0.0746 0.8161 0.8233
Plasmodium vivax proteasome subunit alpha type-4, putative 0.0181 0.1834 0.2004
Giardia lamblia Proteasome subunit beta type 5 precursor 0.0832 0.9125 1
Entamoeba histolytica proteasome subunit alpha type 4, putative 0.0181 0.1834 0.2004
Loa Loa (eye worm) proteasome A-type and B-type family protein 0.0182 0.1839 0.2015
Echinococcus multilocularis subfamily S1A unassigned peptidase (S01 family) 0.0035 0.0195 0.0195
Entamoeba histolytica hypothetical protein 0.0025 0.0086 0.0087
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0038 0.0227 0.0249
Schistosoma mansoni 26S proteasome non-ATPase regulatory subunit 0.003 0.0145 0.0139
Plasmodium vivax hypothetical protein, conserved 0.0038 0.0227 0.0241
Brugia malayi tailless protein 0.003 0.0136 0.013
Loa Loa (eye worm) DR-78 0.003 0.0136 0.015
Trypanosoma brucei proteasome subunit beta type-2, putative 0.0176 0.1775 0.1945
Brugia malayi Eukaryotic-type carbonic anhydrase family protein 0.0157 0.1563 0.1571
Trypanosoma cruzi proteasome beta-1 subunit, putative 0.0182 0.1839 0.2015
Loa Loa (eye worm) hypothetical protein 0.0033 0.0176 0.0193
Onchocerca volvulus 0.0101 0.0938 0.2826
Mycobacterium tuberculosis Probable hydrolase 0.0113 0.1076 0.1132
Loa Loa (eye worm) glutathione reductase 0.0037 0.0215 0.0236
Leishmania major proteasome regulatory non-ATP-ase subunit, putative 0.0027 0.0103 0.0113
Brugia malayi serine/threonine-protein kinase plk-2 0.0312 0.3299 0.3323
Loa Loa (eye worm) hypothetical protein 0.0058 0.0458 0.0502
Brugia malayi Death domain containing protein 0.0033 0.0177 0.0171
Schistosoma mansoni serine/threonine protein kinase 0.0312 0.3299 0.3323
Trichomonas vaginalis 26S proteasome non-ATPase regulatory subunit, putative 0.002 0.0025 0.0028
Schistosoma mansoni nuclear hormone receptor 0.003 0.0136 0.013
Brugia malayi CHD4 protein 0.0038 0.0227 0.0222
Loa Loa (eye worm) hypothetical protein 0.003 0.0136 0.015
Schistosoma mansoni proteasome subunit alpha 1 (T01 family) 0.0181 0.1829 0.184
Giardia lamblia 20S proteasome alpha subunit 1 0.0193 0.1962 0.215
Brugia malayi orphan nuclear receptor NR2E1 0.003 0.0136 0.013
Brugia malayi Adhesion regulating molecule conserved region family protein 0.0087 0.0782 0.0782
Trypanosoma cruzi proteasome subunit alpha type-5, putative 0.0192 0.1952 0.214
Schistosoma mansoni retinoic acid receptor RXR 0.0063 0.0507 0.0505
Schistosoma mansoni hypothetical protein 0.0081 0.071 0.0709
Loa Loa (eye worm) RNA binding protein 0.0139 0.1363 0.1494
Giardia lamblia 26S protease regulatory subunit 8 0.0018 0.0007 0.0008
Leishmania major proteasome alpha 1 subunit, putative 0.0181 0.1829 0.2005
Schistosoma mansoni subfamily S1A unassigned peptidase (S01 family) 0.0035 0.0195 0.0189
Brugia malayi nuclear receptor NHR-88 0.0063 0.0507 0.0505
Echinococcus multilocularis gcn5proteinral control of amino acid synthesis 0.0163 0.1627 0.1627
Mycobacterium tuberculosis holo-[acyl-carrier protein] synthase AcpS (holo-ACP synthase) (CoA:APO-[ACP]pantetheinephosphotransferase) (CoA:APO-[acyl-carrie 0.0025 0.0086 0.0041
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0051 0.0372 0.0375
Loa Loa (eye worm) TAR-binding protein 0.0139 0.1363 0.1494
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0063 0.0507 0.0512
Brugia malayi Nuclear hormone receptor family member nhr-3 0.0063 0.0507 0.0505
Loa Loa (eye worm) eukaryotic-type carbonic anhydrase 0.0157 0.1563 0.1713
Schistosoma mansoni proteasome subunit beta 2 (T01 family) 0.0176 0.1775 0.1785
Entamoeba histolytica calcium-dependent protein kinase 2, putative 0.0152 0.1511 0.165
Loa Loa (eye worm) 26S protease regulatory subunit 8 0.0018 0.0007 0.0008
Echinococcus granulosus proteasome subunit beta t family 0.0176 0.1775 0.1791
Echinococcus granulosus hepatocyte nuclear factor 4 alpha 0.0063 0.0507 0.0512
Echinococcus granulosus tar DNA binding protein 0.0139 0.1363 0.1376
Entamoeba histolytica hypothetical protein 0.0038 0.0228 0.0242
Leishmania major proteasome alpha 7 subunit, putative 0.0227 0.2344 0.2569
Plasmodium vivax proteasome subunit alpha type-2, putative 0.0186 0.1886 0.206
Brugia malayi nuclear hormone receptor 0.003 0.0136 0.013
Entamoeba histolytica 26S protease regulatory subunit, putative 0.0019 0.0013 0.0006
Loa Loa (eye worm) carbonic anhydrase 3 0.0157 0.1563 0.1713
Toxoplasma gondii 'chromo' (CHRromatin Organization MOdifier) domain-containing protein 0.0038 0.0227 0.0241
Schistosoma mansoni 26S protease regulatory subunit 6a 0.002 0.0026 0.0019
Plasmodium vivax proteasome subunit beta type-6, putative 0.0182 0.1839 0.2009
Schistosoma mansoni rab geranylgeranyl transferase alpha subunit 0.0043 0.029 0.0286
Echinococcus multilocularis nuclear receptor subfamily 4 group A 0.003 0.0136 0.0136
Trichomonas vaginalis conserved hypothetical protein 0.0129 0.125 0.1369
Echinococcus granulosus serine:threonine protein kinase PLK1 0.0312 0.3299 0.3328
Schistosoma mansoni hypothetical protein 0.0746 0.8161 0.8233
Trypanosoma cruzi proteasome beta 3 subunit, putative 0.0176 0.1775 0.1945
Echinococcus granulosus glycoprotein Antigen 5 0.0035 0.0195 0.0197
Echinococcus multilocularis Ankyrin 0.0033 0.0178 0.0178
Schistosoma mansoni nuclear receptor 0.003 0.0136 0.013
Entamoeba histolytica chromodomain-helicase-DNA-binding protein, putative 0.0038 0.0227 0.0241
Trichomonas vaginalis Family T1, proteasome beta subunit, threonine peptidase 0.0174 0.1757 0.1926
Loa Loa (eye worm) hypothetical protein 0.003 0.0136 0.015
Leishmania major DNA polymerase kappa, putative 0.0043 0.029 0.0318
Schistosoma mansoni carbonic anhydrase-related 0.0058 0.0458 0.0455
Echinococcus multilocularis netrin receptor unc 5 0.0033 0.0177 0.0177
Toxoplasma gondii 'chromo' (CHRromatin Organization MOdifier) domain-containing protein 0.0038 0.0227 0.0241
Brugia malayi nuclear hormone receptor family member odr-7 0.003 0.0136 0.013
Mycobacterium ulcerans hypothetical protein 0.0035 0.0195 0.0161
Toxoplasma gondii kringle domain-containing protein 0.0018 0.0012 0.0005
Entamoeba histolytica 19S cap proteasome S2 subunit 0.0019 0.0019 0.0013
Schistosoma mansoni 26S proteasome regulatory subunit rpn2 0.0036 0.0204 0.0198
Mycobacterium ulcerans proteasome PrcB 0.0832 0.9125 1
Loa Loa (eye worm) hypothetical protein 0.0033 0.0176 0.0193
Giardia lamblia 26S protease regulatory subunit 6A 0.002 0.0026 0.0028
Plasmodium falciparum 26S proteasome regulatory subunit RPN8, putative 0.0028 0.0119 0.0122
Toxoplasma gondii peptidase, T1 family protein 0.0183 0.1851 0.2022
Echinococcus multilocularis DNA (apurinic or apyrimidinic site) lyase 0.0022 0.0049 0.0049
Trypanosoma cruzi ATP-dependent protease subunit HslV, putative 0.0151 0.15 0.1644
Plasmodium falciparum 26S protease regulatory subunit 4, putative 0.0019 0.0013 0.0006
Leishmania major phosphopantetheinyl transferase-like protein 0.0025 0.0086 0.0095
Loa Loa (eye worm) nuclear hormone receptor family member nhr-41 0.0063 0.0507 0.0556
Plasmodium falciparum proteasome subunit alpha type-2, putative 0.0186 0.1886 0.206
Brugia malayi nuclear hormone receptor family member nhr-6 0.003 0.0136 0.013
Loa Loa (eye worm) multisynthetase complex auxiliary component p43 0.0067 0.0555 0.0608
Loa Loa (eye worm) 26S proteasome non-ATPase regulatory subunit 7 0.0028 0.0119 0.013
Brugia malayi Protein kinase domain containing protein 0.0034 0.0188 0.0182
Entamoeba histolytica proteasome regulatory subunit, putative 0.0034 0.0181 0.0191
Brugia malayi exodeoxyribonuclease III family protein 0.0022 0.0049 0.0042
Loa Loa (eye worm) hypothetical protein 0.0035 0.0195 0.0214
Trypanosoma brucei DNA polymerase kappa, putative 0.0043 0.029 0.0318
Echinococcus multilocularis 26S proteasome non ATPase regulatory subunit 4 0.002 0.0025 0.0025
Echinococcus multilocularis 26S proteasome regulatory subunit S3 0.0036 0.021 0.021
Brugia malayi Type III restriction enzyme, res subunit family protein 0.0038 0.0227 0.0222
Trichomonas vaginalis D-aminoacylase, putative 0.0113 0.1076 0.118
Echinococcus multilocularis proteasome (prosome, macropain) subunit, beta 0.0176 0.1775 0.1775
Entamoeba histolytica chromodomain-helicase-DNA-binding protein, putative 0.0038 0.0227 0.0241
Schistosoma mansoni subfamily S1A unassigned peptidase (S01 family) 0.0035 0.0195 0.0189
Echinococcus granulosus Chromo domain 0.0038 0.0227 0.0229
Echinococcus multilocularis enteropeptidase 0.0035 0.0195 0.0195
Brugia malayi Protein cec-1. 0.0038 0.0227 0.0222
Echinococcus multilocularis carbonic anhydrase 0.0058 0.0458 0.0458
Entamoeba histolytica proteasome subunit alpha type 4, putative 0.0181 0.1834 0.2004
Mycobacterium ulcerans DNA polymerase IV 0.0043 0.029 0.0266
Echinococcus granulosus dna polymerase kappa 0.0043 0.029 0.0293
Trichomonas vaginalis conserved hypothetical protein 0.0038 0.0227 0.0249
Schistosoma mansoni proteasome subunit alpha 7 (T01 family) 0.0227 0.2344 0.236
Echinococcus multilocularis Proteasome, subunit alpha beta 0.0183 0.1851 0.1851
Leishmania major 20s proteasome beta 7 subunit, (putative) 0.0174 0.1757 0.1926
Trypanosoma cruzi DNA polymerase kappa, putative 0.0043 0.029 0.0318
Loa Loa (eye worm) hypothetical protein 0.0038 0.0227 0.0249
Brugia malayi hypothetical protein 0.0038 0.0228 0.0222
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0033 0.0181 0.0175
Brugia malayi 26S proteasome non-ATPase regulatory subunit 7, putative 0.0028 0.0119 0.0112
Echinococcus granulosus Ankyrin 0.0033 0.0178 0.018
Mycobacterium tuberculosis Proteasome alpha subunit PrcA; assembles with beta subunit PrcB. 0.0151 0.15 0.1599
Brugia malayi Hypothetical 52.5 kDa protein ZK945.1 in chromosome II, putative 0.0113 0.1076 0.1079
Trypanosoma cruzi proteasome alpha 1 subunit, putative 0.0193 0.1962 0.215
Plasmodium vivax 26S proteasome AAA-ATPase subunit RPT3, putative 0.0019 0.0013 0.0006
Echinococcus multilocularis ankyrin repeat and death domain containing protein 0.0033 0.0177 0.0177
Schistosoma mansoni nuclear hormone receptor 0.0063 0.0507 0.0505
Loa Loa (eye worm) proteasome subunit alpha type 1 0.0181 0.1829 0.2005
Leishmania major proteasome regulatory non-ATPase subunit 6, putative 0.0034 0.0181 0.0199
Leishmania major DNA polymerase eta, putative 0.0042 0.0276 0.0303
Schistosoma mansoni tar DNA-binding protein 0.0139 0.1363 0.1369
Loa Loa (eye worm) hypothetical protein 0.0058 0.0458 0.0502
Echinococcus granulosus Basic leucine zipper bZIP transcription 0.0038 0.0228 0.023
Brugia malayi hypothetical protein 0.0035 0.0195 0.0189
Onchocerca volvulus 0.0035 0.0195 0.0569
Trypanosoma cruzi 20S proteasome subunit 0.0176 0.1775 0.1945
Schistosoma mansoni glycyl-tRNA synthetase 0.0062 0.0498 0.0495
Plasmodium vivax 26S protease regulatory subunit 6a, putative 0.002 0.0026 0.002
Brugia malayi Nuclear hormone receptor E75 0.003 0.0136 0.013
Entamoeba histolytica 26S proteasome non-ATPase regulatory subunit, putative 0.0028 0.0119 0.0122
Echinococcus multilocularis geminin 0.0746 0.8161 0.8161
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0051 0.0372 0.0368
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0033 0.0181 0.0175
Plasmodium vivax proteasome subunit beta type-4, putative 0.0174 0.1757 0.1919
Trypanosoma cruzi polo-like protein kinase, putative 0.0312 0.3299 0.3615
Trypanosoma cruzi proteasome regulatory ATPase subunit 2, putative 0.0019 0.0013 0.0015
Echinococcus granulosus histone acetyltransferase KAT2B 0.0048 0.0341 0.0344
Schistosoma mansoni proteasome subunit beta 2 (T01 family) 0.0151 0.15 0.1507
Schistosoma mansoni nuclear hormone receptor nor-1/nor-2 0.0063 0.0507 0.0505
Trypanosoma brucei DNA polymerase kappa, putative 0.0043 0.029 0.0318
Brugia malayi Putative carbonic anhydrase 5 precursor 0.0157 0.1563 0.1571
Loa Loa (eye worm) hypothetical protein 0.003 0.0136 0.015
Loa Loa (eye worm) hypothetical protein 0.0129 0.125 0.1369
Trypanosoma brucei DNA polymerase kappa, putative 0.0043 0.029 0.0318
Brugia malayi nuclear receptor RXR 0.0033 0.0176 0.017
Plasmodium falciparum proteasome subunit beta type-7, putative 0.0248 0.2589 0.2831
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0038 0.0227 0.0249
Echinococcus granulosus muscleblind protein 0.016 0.1602 0.1616
Entamoeba histolytica hypothetical protein 0.0038 0.0228 0.0242
Echinococcus granulosus Nuclear hormone receptor HR96 0.003 0.0136 0.0138
Echinococcus multilocularis muscleblind protein 0.016 0.1602 0.1602
Trichomonas vaginalis set domain proteins, putative 0.0266 0.2783 0.305
Trypanosoma cruzi proteasome regulatory non-ATPase subunit 7, putative 0.003 0.0145 0.0159
Schistosoma mansoni multiubiquitin binding protein S5a 0.002 0.0025 0.0018
Echinococcus granulosus 26s protease regulatory subunit 6a 0.002 0.0026 0.0026
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0038 0.0227 0.0249
Trichomonas vaginalis CAMK family protein kinase 0.0154 0.1535 0.1682
Echinococcus multilocularis proteasome (prosome macropain) subunit alpha 0.0181 0.1834 0.1834
Plasmodium vivax heterochromatin protein 1, putative 0.0038 0.0227 0.0241
Plasmodium vivax glutathione reductase, putative 0.0037 0.0215 0.0228
Trypanosoma brucei proteasome regulatory non-ATPase subunit 6 0.0034 0.0181 0.0199
Echinococcus granulosus proteasome prosome macropain 0.0832 0.9125 0.9207
Echinococcus multilocularis 26S proteasome non ATPase regulatory subunit 0.0034 0.0181 0.0181
Loa Loa (eye worm) nuclear hormone receptor family member nhr-31 0.0063 0.0507 0.0556
Trichomonas vaginalis Family T1, proteasome beta subunit, threonine peptidase 0.0182 0.1839 0.2015
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0051 0.0372 0.0372
Plasmodium vivax holo-[acyl-carrier-protein] synthase, putative 0.0025 0.0086 0.0087
Leishmania major proteasome alpha 2 subunit, putative 0.0186 0.1886 0.2067
Echinococcus granulosus Nuclear hormone receptor family member nhr 41 0.0063 0.0507 0.0512
Schistosoma mansoni retinoid-x-receptor (RXR) 0.0063 0.0507 0.0505
Trypanosoma cruzi 19S proteasome non-atpase subunit 8 0.0028 0.0119 0.013
Schistosoma mansoni hypothetical protein 0.0058 0.0458 0.0455
Leishmania major proteasome beta 6 subunit, putative,20S proteasome beta 6 subunit, putative 0.0201 0.206 0.2257
Echinococcus multilocularis glycoprotein Antigen 5 0.0035 0.0195 0.0195
Trypanosoma cruzi proteasome regulatory ATPase subunit 5, putative 0.002 0.0026 0.0028
Trichomonas vaginalis 26S protease regulatory subunit 6A, putative 0.0019 0.0013 0.0015
Schistosoma mansoni tar DNA-binding protein 0.0139 0.1363 0.1369
Schistosoma mansoni 26s proteasome non-ATPase regulatory subunit 4 0.002 0.0025 0.0018
Trichomonas vaginalis penicillin-binding protein, putative 0.0113 0.1076 0.118
Toxoplasma gondii chromodomain helicase DNA binding protein CHD1/SWI2/SNF2 0.0038 0.0227 0.0241
Trichomonas vaginalis CAMK family protein kinase 0.0312 0.3299 0.3615
Plasmodium vivax proteasome subunit beta type-2, putative 0.0176 0.1775 0.1938
Schistosoma mansoni transcription factor LCR-F1 0.0038 0.0228 0.0222
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0063 0.0507 0.0505
Entamoeba histolytica serine/threonine protein kinase, putative 0.0312 0.3299 0.361
Brugia malayi glycyl-tRNA synthetase 0.0062 0.0498 0.0495
Plasmodium falciparum carbonic anhydrase 0.0058 0.0458 0.0494
Entamoeba histolytica proteasome subunit alpha type 6, putative 0.0193 0.1962 0.2144
Onchocerca volvulus 0.0038 0.0227 0.0667
Trypanosoma brucei DNA polymerase IV, putative 0.0043 0.029 0.0318
Loa Loa (eye worm) hypothetical protein 0.0038 0.0228 0.025
Brugia malayi hypothetical protein 0.003 0.0136 0.013
Schistosoma mansoni subfamily T1A non-peptidase homologue (T01 family) 0.0177 0.1784 0.1794
Plasmodium falciparum ATP-dependent protease subunit ClpQ 0.0151 0.15 0.1637
Schistosoma mansoni proteasome catalytic subunit 2 (T01 family) 0.0902 0.9911 1
Schistosoma mansoni netrin receptor unc5 0.0033 0.0177 0.0171
Trypanosoma cruzi proteasome alpha 1 subunit, putative 0.0193 0.1962 0.215
Entamoeba histolytica chromodomain-helicase-DNA-binding protein, putative 0.0038 0.0227 0.0241
Plasmodium falciparum proteasome subunit beta type-6, putative 0.0182 0.1839 0.2009
Brugia malayi Chain A, Structure Of A Brca2-Dss1 Complex. 0.0198 0.2025 0.2038
Schistosoma mansoni thyroid hormone receptor 0.0063 0.0507 0.0505
Schistosoma mansoni subfamily S1A unassigned peptidase (S01 family) 0.0035 0.0195 0.0189
Trichomonas vaginalis cop9 signalosome complex subunit, putative 0.003 0.0145 0.0159
Trypanosoma brucei DNA polymerase kappa, putative 0.003 0.014 0.0153
Echinococcus multilocularis DSS1 (SEM1) domain containing protein 0.0081 0.071 0.071
Trichomonas vaginalis conserved hypothetical protein 0.0091 0.0828 0.0907
Entamoeba histolytica proteasome subunit beta type 3, putative 0.0176 0.1775 0.1938
Brugia malayi nuclear receptor NHR-67 0.003 0.0136 0.013
Giardia lamblia 26S protease regulatory subunit 6B 0.0019 0.0013 0.0015
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0063 0.0507 0.0507
Echinococcus granulosus 26S proteasome non ATPase regulatory subunit 6 0.003 0.0145 0.0147
Echinococcus granulosus chromobox protein 1 0.023 0.2382 0.2403
Brugia malayi Nuclear hormone receptor family member nhr-14 0.0063 0.0507 0.0505
Echinococcus multilocularis 26S proteasome non ATPase regulatory subunit 7 0.0028 0.0119 0.0119
Giardia lamblia Proteasome subunit beta type 3 0.0176 0.1775 0.1945
Mycobacterium leprae PROBABLE NADH DEHYDROGENASE NDH 0.0084 0.0741 0.0724
Echinococcus granulosus FTZ F1 alpha 0.0063 0.0507 0.0512
Entamoeba histolytica hypothetical protein 0.0038 0.0227 0.0241
Brugia malayi Eukaryotic-type carbonic anhydrase family protein 0.0058 0.0458 0.0455
Schistosoma mansoni subfamily S1A unassigned peptidase (S01 family) 0.0035 0.0195 0.0189
Onchocerca volvulus 0.0113 0.1076 0.3248
Schistosoma mansoni hypothetical protein 0.0018 0.0012 0.0005
Echinococcus granulosus 26S proteasome non ATPase regulatory subunit 7 0.0028 0.0119 0.012
Echinococcus granulosus 26S proteasome non ATPase regulatory subunit 0.0034 0.0181 0.0183
Brugia malayi PCI domain containing protein 0.003 0.0147 0.014
Trichomonas vaginalis chromobox protein, putative 0.0038 0.0227 0.0249
Leishmania major proteasome regulatory non-ATP-ase subunit 3, putative 0.0036 0.021 0.023
Trypanosoma brucei DNA polymerase IV, putative 0.0043 0.029 0.0318
Schistosoma mansoni 26S protease regulatory subunit 6a 0.002 0.0026 0.0019
Brugia malayi Nuclear hormone receptor-like 1 0.0033 0.0176 0.017
Trichomonas vaginalis CAMK family protein kinase 0.0312 0.3299 0.3615
Brugia malayi Trypsin family protein 0.0035 0.0195 0.0189
Toxoplasma gondii proteasome subunit alpha2, protease of the acylase family and NTN hydrolase fold, putative 0.0186 0.1886 0.206
Brugia malayi TAR-binding protein 0.0139 0.1363 0.1369
Giardia lamblia 26S protease regulatory subunit 7 0.0018 0.0007 0.0008
Trypanosoma cruzi proteasome alpha 3 subunit, putative 0.0181 0.1834 0.201
Trypanosoma cruzi DNA polymerase kappa, putative 0.0043 0.029 0.0318
Schistosoma mansoni retinoid-x-receptor (RXR) 0.0033 0.0176 0.017
Entamoeba histolytica 26S protease regulatory subunit, putative 0.0019 0.0013 0.0006
Echinococcus granulosus neuropeptide receptor A26 0.0519 0.5619 0.567
Giardia lamblia 26S proteasome regulatory subunit, putative 0.0021 0.0038 0.0042
Brugia malayi Trypsin family protein 0.0035 0.0195 0.0189
Trypanosoma brucei proteasome subunit alpha type-5, putative 0.0192 0.1952 0.214
Trichomonas vaginalis chromobox protein, putative 0.0139 0.1359 0.149
Echinococcus granulosus proteasome subunit alpha type 2 0.0186 0.1886 0.1903
Plasmodium falciparum 26S protease regulatory subunit 6B, putative 0.0019 0.0013 0.0006
Trypanosoma cruzi 19S proteasome regulatory subunit 0.0018 0.0007 0.0008
Loa Loa (eye worm) hypothetical protein 0.0063 0.0507 0.0556
Mycobacterium tuberculosis NADPH-dependent mycothiol reductase Mtr 0.0037 0.0215 0.0183
Entamoeba histolytica hypothetical protein 0.0038 0.0228 0.0242
Loa Loa (eye worm) proteasome subunit beta type 3 0.0176 0.1775 0.1945
Schistosoma mansoni subfamily S1A unassigned peptidase (S01 family) 0.0035 0.0195 0.0189
Mycobacterium tuberculosis Possible penicillin-binding protein 0.0725 0.7927 0.868
Loa Loa (eye worm) hypothetical protein 0.0038 0.0227 0.0249
Loa Loa (eye worm) hypothetical protein 0.003 0.0136 0.015
Loa Loa (eye worm) hypothetical protein 0.0027 0.0103 0.0113
Brugia malayi Thioredoxin reductase 0.0037 0.0215 0.021
Brugia malayi Ubiquitin interaction motif family protein 0.002 0.0025 0.0018
Leishmania major proteasome regulatory ATPase subunit 2, putative 0.0019 0.0013 0.0015
Schistosoma mansoni thyroid hormone receptor 0.0063 0.0507 0.0505
Loa Loa (eye worm) hypothetical protein 0.0063 0.0507 0.0556
Trypanosoma brucei DNA polymerase kappa, putative 0.0043 0.029 0.0318
Schistosoma mansoni proteasome catalytic subunit 3 (T01 family) 0.0832 0.9125 0.9206
Trypanosoma brucei Regulatory particle triple-A ATPase subunit 6 0.0018 0.0007 0.0008
Brugia malayi Nuclear hormone receptor-like 1 0.0063 0.0507 0.0505
Toxoplasma gondii proteasome subunit alpha type, putative 0.0181 0.1834 0.2004
Schistosoma mansoni nuclear receptor 2DBD-gamma 0.0063 0.0507 0.0505
Trichomonas vaginalis chromobox protein, putative 0.023 0.2382 0.261
Trypanosoma cruzi proteasome regulatory non-ATPase subunit, putative 0.002 0.0025 0.0028
Toxoplasma gondii exonuclease III APE 0.0022 0.0049 0.0046
Brugia malayi Trypsin family protein 0.0035 0.0195 0.0189
Trypanosoma cruzi proteasome subunit alpha type-1, putative 0.0181 0.1829 0.2005
Loa Loa (eye worm) proteasome A-type and B-type family protein 0.0832 0.9125 1
Echinococcus granulosus COUP TF:Svp nuclear hormone receptor 0.0063 0.0507 0.0512
Brugia malayi Immunoglobulin I-set domain containing protein 0.0033 0.0177 0.0171
Loa Loa (eye worm) ImpB/MucB/SamB family protein 0.0043 0.029 0.0318
Trichomonas vaginalis D-aminoacylase, putative 0.0113 0.1076 0.118
Toxoplasma gondii ABC1 family protein 0.0113 0.1076 0.1172
Trypanosoma cruzi proteasome regulatory non-ATPase subunit, putative 0.0027 0.0103 0.0113
Loa Loa (eye worm) RPT-2 protein 0.0019 0.0013 0.0015
Loa Loa (eye worm) hypothetical protein 0.0033 0.0177 0.0194
Loa Loa (eye worm) PAS-3 protein 0.0166 0.1666 0.1826
Trypanosoma cruzi hypothetical protein, conserved 0.0018 0.0012 0.0013
Mycobacterium tuberculosis Conserved protein 0.0113 0.1076 0.1132
Echinococcus multilocularis subfamily T1A non peptidase ue 0.0192 0.1952 0.1952
Echinococcus multilocularis proteasome subunit beta (t family) proteasome (prosome macropain) subunit beta 0.0176 0.1775 0.1775
Plasmodium vivax proteasome subunit alpha type-7, putative 0.0227 0.2344 0.2563
Echinococcus granulosus 5'partial|histone lysine N methyltransferase SETDB2 0.0032 0.0167 0.0168
Schistosoma mansoni Tr4/Tr2 (homologue) 0.0063 0.0507 0.0505
Trichomonas vaginalis chromobox protein, putative 0.0038 0.0227 0.0249
Brugia malayi Nuclear hormone receptor family member nhr-41 0.0063 0.0507 0.0505
Loa Loa (eye worm) hypothetical protein 0.0018 0.0007 0.0008
Mycobacterium tuberculosis Probable esterase LipL 0.0113 0.1076 0.1132
Echinococcus granulosus histone acetyltransferase KAT2B 0.0158 0.1576 0.1591
Trichomonas vaginalis Clan MP, family M67, Poh1-like metallopeptidase 0.0028 0.0119 0.013
Schistosoma mansoni tar DNA-binding protein 0.0139 0.1363 0.1369
Trypanosoma brucei DNA polymerase kappa, putative 0.003 0.014 0.0153
Trypanosoma cruzi proteasome beta 6 subunit, putative 0.0201 0.206 0.2257
Schistosoma mansoni proteasome subunit beta 4 (T01 family) 0.0174 0.1757 0.1767
Entamoeba histolytica proteasome regulatory subunit, putative 0.0028 0.0117 0.012
Mycobacterium leprae Probable lipase LipE 0.0113 0.1076 0.1095
Echinococcus granulosus retinoic acid receptor rxr beta a 0.0063 0.0507 0.0512
Schistosoma mansoni FTZ-F1 nuclear receptor-like protein 0.0063 0.0507 0.0505
Trypanosoma brucei proteasome beta 3 subunit, putative 0.0176 0.1775 0.1945
Loa Loa (eye worm) beta-LACTamase domain containing family member 0.0113 0.1076 0.118
Toxoplasma gondii PCI domain-containing protein 0.0036 0.021 0.0222
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0063 0.0507 0.0505
Mycobacterium tuberculosis Probable lipase LipD 0.0113 0.1076 0.1132
Echinococcus granulosus proteasome prosome macropain subunit beta 0.0176 0.1775 0.1791
Plasmodium falciparum proteasome subunit beta type-3, putative 0.0176 0.1775 0.1938
Schistosoma mansoni subfamily S1A unassigned peptidase (S01 family) 0.0035 0.0195 0.0189
Leishmania major proteasome regulatory non-ATP-ase subunit, putative 0.0028 0.0117 0.0128
Plasmodium falciparum holo-[acyl-carrier-protein] synthase, putative 0.0025 0.0086 0.0087
Echinococcus granulosus chromobox protein 1 0.023 0.2382 0.2403
Echinococcus multilocularis 26S protease regulatory subunit 8 0.0018 0.0007 0.0007
Echinococcus multilocularis thyroid hormone receptor alpha 0.0063 0.0507 0.0507
Toxoplasma gondii 26S proteasome regulatory subunit, S6a family AAA ATpase 0.002 0.0026 0.002
Echinococcus multilocularis Proteasome subunit alpha type 7 0.0227 0.2344 0.2344
Trypanosoma cruzi carbonic anhydrase-like protein, putative 0.0157 0.1563 0.1713
Trypanosoma brucei DNA polymerase kappa, putative 0.0043 0.029 0.0318
Onchocerca volvulus 0.0035 0.0195 0.0569
Giardia lamblia Proteasome subunit beta type 1 0.0201 0.206 0.2257
Entamoeba histolytica methionyl-tRNA synthetase, putative 0.008 0.0697 0.0756
Plasmodium falciparum 26S proteasome regulatory subunit RPN12, putative 0.0027 0.0103 0.0105
Echinococcus granulosus Proteasome subunit alpha beta 0.0183 0.1851 0.1868
Echinococcus granulosus tissue type plasminogen activator 0.0018 0.0012 0.0012
Plasmodium vivax 26S proteasome regulatory subunit RPN7, putative 0.003 0.0145 0.0151
Echinococcus multilocularis carbonic anhydrase II 0.0157 0.1563 0.1563
Echinococcus multilocularis dna polymerase kappa 0.0043 0.029 0.029
Brugia malayi Proteasome/cyclosome repeat family protein 0.003 0.0137 0.013
Mycobacterium tuberculosis Probable nitrite reductase [NAD(P)H] large subunit [FAD flavoprotein] NirB 0.0084 0.0741 0.0762
Entamoeba histolytica proteasome regulatory subunit, putative 0.002 0.0025 0.0019
Echinococcus granulosus ecdysone induced protein 78C 0.0063 0.0507 0.0512
Plasmodium falciparum conserved Plasmodium protein, unknown function 0.0038 0.0227 0.0241
Schistosoma mansoni hypothetical protein 0.0028 0.0117 0.0111
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0038 0.0227 0.0249
Entamoeba histolytica probable proteasome subunit beta type 2, putative 0.0176 0.1775 0.1938
Plasmodium vivax 26S proteasome regulatory subunit RPN9, putative 0.0028 0.0117 0.012
Loa Loa (eye worm) MH2 domain-containing protein 0.0132 0.1284 0.1407
Toxoplasma gondii proteasome subunit beta type 7 precursor, putative 0.0248 0.2589 0.2831
Loa Loa (eye worm) hypothetical protein 0.0198 0.2025 0.222
Leishmania major proteasome beta 7 subunit, putative 0.0174 0.1757 0.1926
Trichomonas vaginalis 26S protease regulatory subunit, putative 0.0019 0.0013 0.0015
Onchocerca volvulus 0.0071 0.0602 0.1807
Giardia lamblia 26S proteasome non-ATPase regulatory subunit 2 0.004 0.0253 0.0277
Toxoplasma gondii proteasome subunit alpha1, putative 0.0193 0.1962 0.2144
Schistosoma mansoni proteasome catalytic subunit 1 (T01 family) 0.0182 0.1839 0.1849
Schistosoma mansoni terminal deoxycytidyl transferase 0.0043 0.029 0.0286
Brugia malayi Heterochromatin protein 1 0.023 0.2382 0.2398
Loa Loa (eye worm) nuclear hormone receptor 0.003 0.0136 0.015
Schistosoma mansoni hypothetical protein 0.0198 0.2025 0.2038
Trichomonas vaginalis Family T1, proteasome alpha subunit, threonine peptidase 0.0181 0.1829 0.2005
Mycobacterium tuberculosis Possible conserved lipoprotein LpqK 0.0113 0.1076 0.1132
Plasmodium falciparum histone acetyltransferase GCN5 0.0044 0.0296 0.0317
Entamoeba histolytica proteasome regulatory subunit, putative 0.003 0.0145 0.0151
Trichomonas vaginalis 26S proteasome non-ATPase regulatory subunit, putative 0.0027 0.0103 0.0113
Plasmodium falciparum 26S proteasome regulatory subunit RPN3, putative 0.0036 0.021 0.0222
Trypanosoma cruzi proteasome regulatory non-ATPase subunit 3, putative 0.0036 0.021 0.023
Echinococcus granulosus chromodomain helicase DNA binding protein 4 0.0038 0.0227 0.0229
Echinococcus granulosus netrin receptor unc 5 0.0033 0.0177 0.0178
Trichomonas vaginalis CAMK family protein kinase 0.0312 0.3299 0.3615
Plasmodium falciparum proteasome subunit alpha type-6, putative 0.0193 0.1962 0.2144
Brugia malayi Proteasome regulatory particle, non-atpase-like protein 6 0.0034 0.0181 0.0175
Loa Loa (eye worm) proteasome subunit beta type 2 0.0176 0.1775 0.1945
Leishmania major DNA polymerase kappa, putative,DNA polymerase IV, putative 0.0043 0.029 0.0318
Loa Loa (eye worm) hypothetical protein 0.0035 0.0195 0.0214
Plasmodium vivax proteasome subunit beta type-1, putative 0.0201 0.206 0.2251
Leishmania major hs1vu complex proteolytic subunit-like,hs1vu complex proteolytic subunit-like, threonine peptidase, Clan T(1), family T1B 0.0151 0.15 0.1644
Brugia malayi ecdysteroid receptor 0.0063 0.0507 0.0505
Entamoeba histolytica 26S protease regulatory subunit, putative 0.002 0.0026 0.002
Schistosoma mansoni proteasome subunit alpha 2 (T01 family) 0.0186 0.1886 0.1897
Echinococcus granulosus subfamily S1A unassigned peptidase S01 family 0.0035 0.0195 0.0197
Schistosoma mansoni ap endonuclease 0.0022 0.0049 0.0042
Loa Loa (eye worm) proteasome subunit beta type 1 0.0201 0.206 0.2257
Loa Loa (eye worm) hypothetical protein 0.016 0.1602 0.1755
Leishmania major proteasome regulatory non-ATP-ase subunit 5, putative,19S proteasome regulatory subunit 0.003 0.0147 0.0161
Leishmania major proteasome regulatory ATPase subunit 5, putative 0.002 0.0026 0.0028
Plasmodium falciparum 26S proteasome regulatory subunit RPN9, putative 0.0028 0.0117 0.012
Brugia malayi Trypsin-like protease protein 5 0.0035 0.0195 0.0189
Plasmodium vivax AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.0022 0.0049 0.0046
Trichomonas vaginalis Family T1, proteasome alpha subunit, threonine peptidase 0.0181 0.1834 0.201
Loa Loa (eye worm) hypothetical protein 0.0113 0.1076 0.118
Toxoplasma gondii 20S proteasome subunit beta 7, putative 0.0174 0.1757 0.1919
Loa Loa (eye worm) hypothetical protein 0.0058 0.0458 0.0502
Brugia malayi Proteasome subunit alpha type 1 0.0166 0.1661 0.167
Brugia malayi Proteasome A-type and B-type family protein 0.0902 0.9911 1
Brugia malayi Eukaryotic-type carbonic anhydrase family protein 0.0058 0.0458 0.0455
Echinococcus granulosus 26S proteasome non ATPase regulatory subunit 0.0036 0.0204 0.0205
Trypanosoma brucei proteasome regulatory ATPase subunit 3 0.0019 0.0013 0.0015
Echinococcus multilocularis chromobox protein 1 0.023 0.2382 0.2382
Echinococcus granulosus dna polymerase eta 0.0072 0.0611 0.0616
Brugia malayi Proteasome A-type and B-type family protein 0.0174 0.1757 0.1767
Brugia malayi Proteasome/cyclosome repeat family protein 0.003 0.0137 0.013
Schistosoma mansoni proteasome subunit beta 3 (T01 family) 0.0176 0.1775 0.1785
Loa Loa (eye worm) hypothetical protein 0.0025 0.008 0.0088
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0038 0.0227 0.0249
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0063 0.0507 0.0505
Trypanosoma brucei 26S proteasome regulatory non-ATPase subunit 0.004 0.0253 0.0277
Echinococcus multilocularis tar DNA binding protein 0.0139 0.1363 0.1363
Toxoplasma gondii PCI domain-containing protein 0.0034 0.0181 0.0191
Onchocerca volvulus 0.0019 0.0013 0.0018
Trichomonas vaginalis chromobox protein, putative 0.023 0.2382 0.261
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0051 0.0372 0.0368
Schistosoma mansoni nuclear receptor nhr-48 0.003 0.0136 0.013
Echinococcus granulosus subfamily T1A non peptidase ue 0.0192 0.1952 0.197
Leishmania major proteasome beta-1 subunit, putative 0.0182 0.1839 0.2015
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0038 0.0227 0.0249
Schistosoma mansoni aminopeptidase PILS (M01 family) 0.0035 0.0195 0.0189
Leishmania major DNA polymerase eta, putative 0.0072 0.0611 0.0669
Trypanosoma cruzi DNA polymerase kappa, putative 0.0043 0.029 0.0318
Echinococcus multilocularis 26S proteasome regulatory subunit N11 0.0028 0.0119 0.0119
Brugia malayi nuclear receptor RXR 0.003 0.0136 0.013
Leishmania major hypothetical protein, conserved 0.0113 0.1076 0.118
Echinococcus granulosus beta LACTamase domain containing family member 0.0113 0.1076 0.1086
Echinococcus multilocularis chromodomain helicase DNA binding protein 4 0.0038 0.0227 0.0227
Onchocerca volvulus 0.0019 0.0013 0.0018
Trypanosoma brucei unspecified product 0.003 0.014 0.0153
Trypanosoma cruzi proteasome regulatory ATPase subunit 2, putative 0.0019 0.0013 0.0015
Schistosoma mansoni histone-lysine n-methyltransferase suv9 0.0071 0.0602 0.0601
Schistosoma mansoni proteasome subunit beta 3 (T01 family) 0.0176 0.1775 0.1785
Mycobacterium leprae proteasome (beta subunit) PrcB 0.0832 0.9125 1
Brugia malayi SET domain containing protein 0.0039 0.0241 0.0236
Trypanosoma cruzi proteasome beta 6 subunit, putative 0.0201 0.206 0.2257
Trypanosoma cruzi 26S protease regulatory subunit, putative 0.0018 0.0007 0.0008
Loa Loa (eye worm) hypothetical protein 0.0038 0.0227 0.0249
Loa Loa (eye worm) GTP-binding regulatory protein Gs alpha-S chain 0.0051 0.0372 0.0407
Schistosoma mansoni aminoadipate-semialdehyde dehydrogenase 0.0089 0.0805 0.0805
Echinococcus granulosus L aminoadipate semialdehyde 0.0089 0.0805 0.0812
Trypanosoma cruzi proteasome alpha 2 subunit, putative 0.0171 0.1718 0.1883
Onchocerca volvulus Protein ultraspiracle homolog 0.0063 0.0507 0.1519
Schistosoma mansoni proteasome subunit alpha 4 (T01 family) 0.0181 0.1834 0.1845
Schistosoma mansoni steroid hormone receptor ad4bp 0.0063 0.0507 0.0505
Brugia malayi chromobox protein homolog 3 0.0129 0.125 0.1254
Leishmania major 20s proteasome beta 7 subunit, (putative) 0.0174 0.1757 0.1926
Brugia malayi beta-lactamase 0.0113 0.1076 0.1079
Echinococcus granulosus thyroid hormone receptor alpha 0.003 0.0136 0.0138
Schistosoma mansoni 26S protease regulatory subunit 6b 0.0019 0.0013 0.0006
Echinococcus multilocularis proteasome (prosome macropain) subunit beta type 0.0174 0.1757 0.1757
Brugia malayi bifunctional aminoacyl-tRNA synthetase 0.0062 0.0498 0.0495
Trypanosoma brucei proteasome subunit beta type-5, putative 0.0832 0.9125 1
Schistosoma mansoni 26S proteasome subunit S9 0.0034 0.0181 0.0175
Trypanosoma cruzi proteasome subunit beta type-5, putative 0.0832 0.9125 1
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0038 0.0227 0.0249
Leishmania major 26S protease regulatory subunit, putative,serine peptidase, Clan SJ, family S16, putative 0.0018 0.0007 0.0008
Echinococcus multilocularis 26s protease regulatory subunit s10b 0.0018 0.0007 0.0007
Trypanosoma cruzi proteasome alpha 3 subunit, putative 0.0181 0.1834 0.201
Trichomonas vaginalis 26S proteasome non-ATPase regulatory subunit, putative 0.0027 0.0103 0.0113
Entamoeba histolytica proteasome subunit beta Type 4 precursor, putative 0.0174 0.1757 0.1919
Schistosoma mansoni chromobox protein 0.023 0.2382 0.2398
Trypanosoma cruzi proteasome beta 3 subunit, putative 0.0176 0.1775 0.1945
Loa Loa (eye worm) 26S protease regulatory subunit 6A 0.002 0.0026 0.0028
Toxoplasma gondii 4'-phosphopantetheinyl transferase domain-containing protein 0.0025 0.0086 0.0087
Plasmodium vivax 26S proteasome regulatory subunit p55, putative 0.003 0.0147 0.0153
Echinococcus granulosus nuclear receptor 2DBD gamma 0.003 0.0136 0.0138
Echinococcus multilocularis COUP TF:Svp nuclear hormone receptor 0.0063 0.0507 0.0507
Schistosoma mansoni hypothetical protein 0.0038 0.0227 0.0222
Echinococcus multilocularis neuropeptide receptor A26 0.0519 0.5619 0.5619
Leishmania major proteasome beta 3 subunit, putative 0.0176 0.1775 0.1945
Leishmania major hypothetical protein, conserved 0.0018 0.0012 0.0013
Trichomonas vaginalis Family T1, proteasome beta subunit, threonine peptidase 0.0176 0.1775 0.1945
Leishmania major 20s proteasome beta 7 subunit, (putative) 0.0174 0.1757 0.1926
Trypanosoma brucei hypothetical protein, conserved 0.0025 0.0086 0.0095
Giardia lamblia Proteasome subunit beta type 7 precursor 0.0248 0.2589 0.2837
Schistosoma mansoni adhesion regulating molecule 1 (110 kD cell membrane glycoprotein) 0.0087 0.0782 0.0782
Toxoplasma gondii proteasome regulatory subunit 0.0028 0.0119 0.0122
Loa Loa (eye worm) exodeoxyribonuclease III family protein 0.0022 0.0049 0.0054
Trichomonas vaginalis Clan MP, family M67, Poh1-like metallopeptidase 0.0028 0.0119 0.013
Trypanosoma cruzi proteasome alpha 7 subunit, putative 0.0183 0.1851 0.2029
Mycobacterium tuberculosis Conserved protein 0.0113 0.1076 0.1132
Trypanosoma brucei proteasome regulatory ATPase subunit 5 0.002 0.0026 0.0028
Echinococcus granulosus Chromobox protein 3 0.0038 0.0227 0.0229
Loa Loa (eye worm) PCI domain-containing protein 0.003 0.0147 0.0161
Brugia malayi M-phase phosphoprotein, mpp8 0.0038 0.0227 0.0222
Schistosoma mansoni carbonic anhydrase-related 0.0058 0.0458 0.0455
Loa Loa (eye worm) hypothetical protein 0.003 0.0136 0.015
Loa Loa (eye worm) hypothetical protein 0.0033 0.0176 0.0193
Brugia malayi Nuclear hormone receptor family member nhr-49 0.0063 0.0507 0.0505
Loa Loa (eye worm) hypothetical protein 0.0072 0.0611 0.0669
Toxoplasma gondii Mov34/MPN/PAD-1 family protein 0.0028 0.0119 0.0122
Trypanosoma brucei proteasome beta 6 subunit 0.0201 0.206 0.2257
Mycobacterium ulcerans esterase/lipase LipP 0.0113 0.1076 0.1132
Loa Loa (eye worm) hypothetical protein 0.0087 0.0782 0.0857
Brugia malayi ecdysone receptor 0.003 0.0136 0.013
Loa Loa (eye worm) hypothetical protein 0.003 0.0136 0.015
Brugia malayi conserved hypotetical protein 0.003 0.0136 0.013
Trichomonas vaginalis CAMK family protein kinase 0.0154 0.1535 0.1682
Brugia malayi Trypsin family protein 0.0035 0.0195 0.0189
Loa Loa (eye worm) proteasome subunit alpha type 6 0.0193 0.1962 0.215
Echinococcus multilocularis methionyl tRNA synthetase, cytoplasmic 0.008 0.0697 0.0697
Entamoeba histolytica proteasome regulatory subunit, putative 0.0027 0.0103 0.0105
Onchocerca volvulus 0.0113 0.1076 0.3248
Brugia malayi Protein kinase domain containing protein 0.0018 0.0012 0.0005
Giardia lamblia Proteasome subunit beta type 4 precursor 0.0174 0.1757 0.1926
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0038 0.0227 0.0249
Trypanosoma brucei trypanothione reductase 0.0037 0.0215 0.0236
Schistosoma mansoni gcn5proteinral control of amino-acid synthesis 5-like 2 gcnl2 0.0163 0.1627 0.1636
Trichomonas vaginalis Family T1, proteasome beta subunit, threonine peptidase 0.0201 0.206 0.2257
Schistosoma mansoni ankyrin 23/unc44 0.0033 0.0177 0.0171
Loa Loa (eye worm) hypothetical protein 0.0035 0.0195 0.0214
Loa Loa (eye worm) RPN-3 protein 0.0036 0.021 0.023
Brugia malayi nuclear hormone receptor 0.0063 0.0507 0.0505
Trichomonas vaginalis 26S proteasome regulatory subunit rpn1, putative 0.0021 0.0038 0.0042
Loa Loa (eye worm) hypothetical protein 0.0063 0.0507 0.0556
Toxoplasma gondii histone lysine acetyltransferase GCN5-A 0.0048 0.0341 0.0366
Loa Loa (eye worm) hypothetical protein 0.0113 0.1076 0.118
Loa Loa (eye worm) nuclear receptor nhr-7B 0.003 0.0136 0.015
Giardia lamblia 20S proteasome alpha subunit 3 0.0181 0.1834 0.201
Trypanosoma brucei DNA polymerase kappa, putative 0.0043 0.029 0.0318
Schistosoma mansoni RAR-like nuclear receptor 0.0063 0.0507 0.0505
Echinococcus multilocularis ecdysone induced protein 78C 0.0063 0.0507 0.0507

Activities

Activity type Activity value Assay description Source Reference
MIC (functional) = 0.5 ug ml-1 Antibacterial activity of compound was determined against Escherichia coli JM109 ChEMBL. 10360737
MIC (functional) = 32 ug ml-1 Antibacterial activity of compound was determined against Bacillus cereus ATCC 27348 ChEMBL. 10360737
MIC (functional) > 64 ug ml-1 Antibacterial activity of compound was determined against Staphylococcus aureus 1538p ChEMBL. 10360737
MIC (functional) > 64 ug ml-1 Antibacterial activity of compound was determined against Streptococcus epidermidis 887E ChEMBL. 10360737
MIC (functional) > 64 ug ml-1 Antibacterial activity of compound was determined against Salmonella typhimurium 14028 ChEMBL. 10360737
MIC (functional) > 64 ug ml-1 Antibacterial activity of compound was determined against Klebsiella pneumoniae 2011E ChEMBL. 10360737
MIC (functional) > 64 ug ml-1 Antibacterial activity of compound was determined against Klebsiella aerogenes 1976E ChEMBL. 10360737
MIC (functional) > 64 ug ml-1 Antibacterial activity of compound was determined against Pseudomonas aeruginosa 1912 ChEMBL. 10360737

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
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External resources for this compound

Bibliographic References

1 literature reference was collected for this gene.

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