Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Echinococcus granulosus | rhodopsin orphan GPCR | 0.0229 | 0.1086 | 0.1086 |
Echinococcus multilocularis | neuropeptide FF receptor 2 | 0.0229 | 0.1086 | 0.1086 |
Schistosoma mansoni | peptide (FMRFamide/somatostatin)-like receptor | 0.0229 | 0.1086 | 0.1086 |
Brugia malayi | gonadotropin-releasing hormone receptor 2 | 0.0229 | 0.1086 | 0.1086 |
Echinococcus granulosus | neuropeptide receptor | 0.0229 | 0.1086 | 0.1086 |
Echinococcus multilocularis | rhodopsin orphan GPCR | 0.0229 | 0.1086 | 0.1086 |
Loa Loa (eye worm) | hypothetical protein | 0.0229 | 0.1086 | 0.1086 |
Loa Loa (eye worm) | hypothetical protein | 0.0229 | 0.1086 | 0.1086 |
Schistosoma mansoni | neuropeptide f receptor 76f | 0.0229 | 0.1086 | 0.1086 |
Loa Loa (eye worm) | hypothetical protein | 0.0229 | 0.1086 | 0.1086 |
Echinococcus granulosus | rhodopsin orphan GPCR | 0.0229 | 0.1086 | 0.1086 |
Brugia malayi | G protein-coupled receptor F59B2.13 | 0.0229 | 0.1086 | 0.1086 |
Brugia malayi | Melatonin receptor type 1A | 0.0229 | 0.1086 | 0.1086 |
Echinococcus granulosus | serotonin receptor | 0.0229 | 0.1086 | 0.1086 |
Brugia malayi | Serotonin/octopamine receptor family protein 7 | 0.0229 | 0.1086 | 0.1086 |
Echinococcus granulosus | neuropeptide FF receptor 2 | 0.0229 | 0.1086 | 0.1086 |
Echinococcus multilocularis | rhodopsin orphan GPCR | 0.0229 | 0.1086 | 0.1086 |
Schistosoma mansoni | peptide (allatostatin/somatostatin)-like receptor | 0.0229 | 0.1086 | 0.1086 |
Loa Loa (eye worm) | G-protein-linked acetylcholine receptor protein 2 | 0.0229 | 0.1086 | 0.1086 |
Brugia malayi | neuropeptide F receptor | 0.0229 | 0.1086 | 0.1086 |
Schistosoma mansoni | biogenic amine (dopamine) receptor | 0.0229 | 0.1086 | 0.1086 |
Echinococcus granulosus | g protein coupled receptor | 0.0229 | 0.1086 | 0.1086 |
Echinococcus multilocularis | sex peptide receptor | 0.0229 | 0.1086 | 0.1086 |
Schistosoma mansoni | neuropeptide F-like receptor | 0.0229 | 0.1086 | 0.1086 |
Loa Loa (eye worm) | G-protein coupled receptor | 0.0229 | 0.1086 | 0.1086 |
Loa Loa (eye worm) | hypothetical protein | 0.0229 | 0.1086 | 0.1086 |
Schistosoma mansoni | rhodopsin-like orphan GPCR | 0.0229 | 0.1086 | 0.1086 |
Echinococcus multilocularis | tm gpcr rhodopsin gpcr rhodopsin superfamily | 0.0229 | 0.1086 | 0.1086 |
Plasmodium falciparum | bifunctional dihydrofolate reductase-thymidylate synthase | 0.0794 | 1 | 0.5 |
Loa Loa (eye worm) | hypothetical protein | 0.0229 | 0.1086 | 0.1086 |
Echinococcus multilocularis | neuropeptide Y receptor | 0.0229 | 0.1086 | 0.1086 |
Brugia malayi | hypothetical protein | 0.0229 | 0.1086 | 0.1086 |
Brugia malayi | hypothetical protein | 0.0229 | 0.1086 | 0.1086 |
Loa Loa (eye worm) | hypothetical protein | 0.0229 | 0.1086 | 0.1086 |
Loa Loa (eye worm) | hypothetical protein | 0.0229 | 0.1086 | 0.1086 |
Loa Loa (eye worm) | neuropeptide F receptor | 0.0229 | 0.1086 | 0.1086 |
Echinococcus multilocularis | G protein coupled 5 hydroxytryptamine receptor | 0.0229 | 0.1086 | 0.1086 |
Echinococcus multilocularis | fmrfamide receptor | 0.0229 | 0.1086 | 0.1086 |
Echinococcus multilocularis | metabotropic glutamate receptor 2 | 0.0276 | 0.1827 | 0.1827 |
Schistosoma mansoni | adenoreceptor | 0.0229 | 0.1086 | 0.1086 |
Echinococcus granulosus | neuropeptide receptor | 0.0229 | 0.1086 | 0.1086 |
Echinococcus multilocularis | rhodopsin orphan GPCR | 0.0229 | 0.1086 | 0.1086 |
Echinococcus granulosus | hypothetical protein | 0.0229 | 0.1086 | 0.1086 |
Echinococcus multilocularis | neuropeptide receptor A26 | 0.0229 | 0.1086 | 0.1086 |
Brugia malayi | hypothetical protein | 0.0229 | 0.1086 | 0.1086 |
Echinococcus granulosus | tm gpcr rhodopsin | 0.0229 | 0.1086 | 0.1086 |
Echinococcus granulosus | tm gpcr rhodopsin | 0.0229 | 0.1086 | 0.1086 |
Brugia malayi | G-protein-linked acetylcholine receptor protein 2, putative | 0.0229 | 0.1086 | 0.1086 |
Loa Loa (eye worm) | glutamate receptor | 0.033 | 0.2673 | 0.2673 |
Schistosoma mansoni | growth hormone secretagogue receptor | 0.0229 | 0.1086 | 0.1086 |
Echinococcus granulosus | G protein coupled 5 hydroxytryptamine receptor | 0.0229 | 0.1086 | 0.1086 |
Echinococcus granulosus | 7tm_1 domain containing protein | 0.0229 | 0.1086 | 0.1086 |
Schistosoma mansoni | rhodopsin-like orphan GPCR | 0.0229 | 0.1086 | 0.1086 |
Loa Loa (eye worm) | hypothetical protein | 0.0229 | 0.1086 | 0.1086 |
Echinococcus granulosus | allatostatin A receptor | 0.0229 | 0.1086 | 0.1086 |
Schistosoma mansoni | hypothetical protein | 0.0229 | 0.1086 | 0.1086 |
Loa Loa (eye worm) | unidentified vitellogenin-linked transcript protein 6 | 0.0229 | 0.1086 | 0.1086 |
Schistosoma mansoni | hypothetical protein | 0.0229 | 0.1086 | 0.1086 |
Echinococcus granulosus | neuropeptide receptor A26 | 0.0229 | 0.1086 | 0.1086 |
Echinococcus multilocularis | G protein coupled receptor 139 | 0.0229 | 0.1086 | 0.1086 |
Brugia malayi | hypothetical protein | 0.0229 | 0.1086 | 0.1086 |
Echinococcus multilocularis | alpha 1A adrenergic receptor | 0.0229 | 0.1086 | 0.1086 |
Echinococcus multilocularis | g protein linked acetylcholine receptor gar 2a | 0.0229 | 0.1086 | 0.1086 |
Loa Loa (eye worm) | follicle stimulating hormone receptor | 0.0229 | 0.1086 | 0.1086 |
Echinococcus granulosus | tachykinin peptides receptor 99D | 0.0229 | 0.1086 | 0.1086 |
Schistosoma mansoni | amine GPCR | 0.0229 | 0.1086 | 0.1086 |
Loa Loa (eye worm) | hypothetical protein | 0.0406 | 0.3877 | 0.3877 |
Brugia malayi | Dopamine receptor protein 1 | 0.0229 | 0.1086 | 0.1086 |
Brugia malayi | hypothetical protein | 0.0229 | 0.1086 | 0.1086 |
Echinococcus multilocularis | neuropeptide receptor | 0.0229 | 0.1086 | 0.1086 |
Echinococcus granulosus | metabotropic glutamate receptor 2 | 0.0276 | 0.1827 | 0.1827 |
Echinococcus granulosus | tm gpcr rhodopsin | 0.0229 | 0.1086 | 0.1086 |
Loa Loa (eye worm) | hypothetical protein | 0.0229 | 0.1086 | 0.1086 |
Echinococcus granulosus | neuropeptide Y receptor | 0.0229 | 0.1086 | 0.1086 |
Echinococcus granulosus | rhodopsin orphan GPCR | 0.0229 | 0.1086 | 0.1086 |
Schistosoma mansoni | biogenic amine (dopamine) receptor | 0.0229 | 0.1086 | 0.1086 |
Echinococcus granulosus | rhodopsin orphan GPCR | 0.0229 | 0.1086 | 0.1086 |
Schistosoma mansoni | hypothetical protein | 0.0229 | 0.1086 | 0.1086 |
Loa Loa (eye worm) | hypothetical protein | 0.0229 | 0.1086 | 0.1086 |
Entamoeba histolytica | hypothetical protein | 0.0161 | 0 | 0.5 |
Brugia malayi | putative neuropeptide receptor | 0.0229 | 0.1086 | 0.1086 |
Schistosoma mansoni | biogenic amine receptor | 0.0229 | 0.1086 | 0.1086 |
Echinococcus granulosus | neuropeptide Y receptor | 0.0229 | 0.1086 | 0.1086 |
Loa Loa (eye worm) | thymidylate synthase | 0.0794 | 1 | 1 |
Echinococcus multilocularis | thymidylate synthase | 0.0794 | 1 | 1 |
Brugia malayi | larval opioid receptor | 0.0229 | 0.1086 | 0.1086 |
Echinococcus multilocularis | biogenic amine (5HT) receptor | 0.0229 | 0.1086 | 0.1086 |
Echinococcus multilocularis | rhodopsin orphan GPCR | 0.0229 | 0.1086 | 0.1086 |
Brugia malayi | metabotropic glutamate receptor type 2 | 0.0161 | 0.0002 | 0.0002 |
Echinococcus multilocularis | serotonin receptor | 0.0229 | 0.1086 | 0.1086 |
Echinococcus granulosus | pyroglutamylated rfamide peptide receptor | 0.0229 | 0.1086 | 0.1086 |
Brugia malayi | follicle stimulating hormone receptor | 0.0229 | 0.1086 | 0.1086 |
Echinococcus granulosus | neuropeptides capa receptor | 0.0229 | 0.1086 | 0.1086 |
Echinococcus granulosus | neuropeptide s receptor | 0.0229 | 0.1086 | 0.1086 |
Brugia malayi | hypothetical protein | 0.0229 | 0.1086 | 0.1086 |
Brugia malayi | Tachykinin-like peptides receptor 99D | 0.0229 | 0.1086 | 0.1086 |
Brugia malayi | sulfakinin receptor protein | 0.0229 | 0.1086 | 0.1086 |
Loa Loa (eye worm) | hypothetical protein | 0.0229 | 0.1086 | 0.1086 |
Loa Loa (eye worm) | hypothetical protein | 0.0229 | 0.1086 | 0.1086 |
Echinococcus granulosus | g-protein coupled receptor | 0.0229 | 0.1086 | 0.1086 |
Loa Loa (eye worm) | neuropeptide F receptor | 0.0229 | 0.1086 | 0.1086 |
Echinococcus granulosus | g protein coupled receptor | 0.0229 | 0.1086 | 0.1086 |
Brugia malayi | Serotonin receptor | 0.0229 | 0.1086 | 0.1086 |
Loa Loa (eye worm) | hypothetical protein | 0.0229 | 0.1086 | 0.1086 |
Schistosoma mansoni | biogenic amine (5HT) receptor | 0.0229 | 0.1086 | 0.1086 |
Brugia malayi | Metabotropic glutamate receptor precursor. | 0.033 | 0.2673 | 0.2673 |
Echinococcus granulosus | thyrotropin releasing hormone receptor | 0.0229 | 0.1086 | 0.1086 |
Loa Loa (eye worm) | hypothetical protein | 0.0229 | 0.1086 | 0.1086 |
Schistosoma mansoni | amine GPCR | 0.0229 | 0.1086 | 0.1086 |
Loa Loa (eye worm) | hypothetical protein | 0.0229 | 0.1086 | 0.1086 |
Loa Loa (eye worm) | hypothetical protein | 0.0229 | 0.1086 | 0.1086 |
Schistosoma mansoni | biogenic amine (5HT) receptor | 0.0229 | 0.1086 | 0.1086 |
Schistosoma mansoni | opsin-like receptor | 0.0229 | 0.1086 | 0.1086 |
Echinococcus granulosus | biogenic amine 5HT receptor | 0.0229 | 0.1086 | 0.1086 |
Schistosoma mansoni | neuropeptide F-like receptor | 0.0229 | 0.1086 | 0.1086 |
Loa Loa (eye worm) | hypothetical protein | 0.0229 | 0.1086 | 0.1086 |
Schistosoma mansoni | rhodopsin-like orphan GPCR | 0.0229 | 0.1086 | 0.1086 |
Echinococcus granulosus | G protein coupled receptor 139 | 0.0229 | 0.1086 | 0.1086 |
Loa Loa (eye worm) | hypothetical protein | 0.0229 | 0.1086 | 0.1086 |
Loa Loa (eye worm) | hypothetical protein | 0.0229 | 0.1086 | 0.1086 |
Brugia malayi | G protein-coupled receptor | 0.0229 | 0.1086 | 0.1086 |
Schistosoma mansoni | alpha-1 adrenergic receptor | 0.0229 | 0.1086 | 0.1086 |
Echinococcus granulosus | orexin receptor type 2 | 0.0229 | 0.1086 | 0.1086 |
Schistosoma mansoni | opsin-like receptor | 0.0229 | 0.1086 | 0.1086 |
Echinococcus granulosus | biogenic amine 5HT receptor | 0.0229 | 0.1086 | 0.1086 |
Schistosoma mansoni | biogenic amine (octopamine/dopamine) receptor | 0.0229 | 0.1086 | 0.1086 |
Echinococcus multilocularis | rhodopsin orphan GPCR | 0.0229 | 0.1086 | 0.1086 |
Schistosoma mansoni | rhodopsin-like orphan GPCR | 0.0229 | 0.1086 | 0.1086 |
Echinococcus multilocularis | somatostatin receptor | 0.0229 | 0.1086 | 0.1086 |
Schistosoma mansoni | metabotropic glutamate receptor | 0.0276 | 0.1827 | 0.1827 |
Brugia malayi | AKH receptor | 0.0229 | 0.1086 | 0.1086 |
Schistosoma mansoni | rhodopsin-like orphan GPCR | 0.0229 | 0.1086 | 0.1086 |
Echinococcus granulosus | peptide allatostatin:somatostatin | 0.0229 | 0.1086 | 0.1086 |
Brugia malayi | Unidentified vitellogenin-linked transcript protein 6, putative | 0.0229 | 0.1086 | 0.1086 |
Loa Loa (eye worm) | hypothetical protein | 0.0229 | 0.1086 | 0.1086 |
Echinococcus granulosus | rhodopsin orphan GPCR | 0.0229 | 0.1086 | 0.1086 |
Loa Loa (eye worm) | hypothetical protein | 0.0229 | 0.1086 | 0.1086 |
Brugia malayi | Dopamine receptor protein 1, putative (partial) | 0.0229 | 0.1086 | 0.1086 |
Brugia malayi | hypothetical protein | 0.0378 | 0.3427 | 0.3427 |
Schistosoma mansoni | neuropeptide receptor | 0.0229 | 0.1086 | 0.1086 |
Schistosoma mansoni | peptide (allatostatin)-like receptor | 0.0229 | 0.1086 | 0.1086 |
Echinococcus granulosus | somatostatin receptor | 0.0229 | 0.1086 | 0.1086 |
Loa Loa (eye worm) | hypothetical protein | 0.0229 | 0.1086 | 0.1086 |
Echinococcus multilocularis | rhodopsin orphan GPCR | 0.0229 | 0.1086 | 0.1086 |
Schistosoma mansoni | biogenic amine receptor | 0.0229 | 0.1086 | 0.1086 |
Echinococcus multilocularis | tm gpcr rhodopsin gpcr rhodopsin superfamily | 0.0229 | 0.1086 | 0.1086 |
Echinococcus multilocularis | 7TM GPCR, rhodopsin | 0.0229 | 0.1086 | 0.1086 |
Schistosoma mansoni | peptide (FMRFamide/neurokinin-3)-like receptor | 0.0229 | 0.1086 | 0.1086 |
Echinococcus multilocularis | allatostatin A receptor | 0.0229 | 0.1086 | 0.1086 |
Echinococcus granulosus | alpha 1A adrenergic receptor | 0.0229 | 0.1086 | 0.1086 |
Schistosoma mansoni | amine GPCR | 0.0229 | 0.1086 | 0.1086 |
Onchocerca volvulus | 0.0794 | 1 | 1 | |
Echinococcus multilocularis | dro:myosuppressin receptor | 0.0229 | 0.1086 | 0.1086 |
Brugia malayi | Dopamine receptor protein 2 | 0.0229 | 0.1086 | 0.1086 |
Brugia malayi | Serotonin receptor | 0.0229 | 0.1086 | 0.1086 |
Loa Loa (eye worm) | hypothetical protein | 0.0229 | 0.1086 | 0.1086 |
Echinococcus granulosus | g protein coupled receptor | 0.0229 | 0.1086 | 0.1086 |
Echinococcus multilocularis | neuropeptides capa receptor | 0.0229 | 0.1086 | 0.1086 |
Echinococcus multilocularis | peptide (allatostatin:somatostatin) | 0.0229 | 0.1086 | 0.1086 |
Echinococcus multilocularis | rhodopsin orphan GPCR | 0.0229 | 0.1086 | 0.1086 |
Echinococcus multilocularis | tachykinin peptides receptor 99D | 0.0229 | 0.1086 | 0.1086 |
Echinococcus multilocularis | rhodopsin orphan GPCR | 0.0229 | 0.1086 | 0.1086 |
Brugia malayi | hypothetical protein | 0.0229 | 0.1086 | 0.1086 |
Schistosoma mansoni | metabotropic glutamate receptor | 0.0161 | 0.0002 | 0.0002 |
Echinococcus multilocularis | g protein coupled receptor | 0.0229 | 0.1086 | 0.1086 |
Echinococcus multilocularis | metabotropic glutamate receptor 5 | 0.0406 | 0.3877 | 0.3877 |
Entamoeba histolytica | poly(ADP-ribose) glycohydrolase, putative | 0.0161 | 0 | 0.5 |
Schistosoma mansoni | rhodopsin-like orphan GPCR | 0.0229 | 0.1086 | 0.1086 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0378 | 0.3427 | 0.5 |
Schistosoma mansoni | amine GPCR | 0.0229 | 0.1086 | 0.1086 |
Loa Loa (eye worm) | hypothetical protein | 0.0229 | 0.1086 | 0.1086 |
Echinococcus multilocularis | neuropeptide Y receptor | 0.0229 | 0.1086 | 0.1086 |
Loa Loa (eye worm) | hypothetical protein | 0.0229 | 0.1086 | 0.1086 |
Brugia malayi | RE15519p | 0.0229 | 0.1086 | 0.1086 |
Echinococcus granulosus | growth hormone secretagogue receptor type 1 | 0.0229 | 0.1086 | 0.1086 |
Echinococcus multilocularis | neuropeptide receptor | 0.0229 | 0.1086 | 0.1086 |
Echinococcus granulosus | g protein linked acetylcholine receptor gar 2a | 0.0229 | 0.1086 | 0.1086 |
Loa Loa (eye worm) | hypothetical protein | 0.0229 | 0.1086 | 0.1086 |
Schistosoma mansoni | bifunctional dihydrofolate reductase-thymidylate synthase | 0.0794 | 1 | 1 |
Brugia malayi | G-protein coupled receptor | 0.0229 | 0.1086 | 0.1086 |
Brugia malayi | G-protein coupled receptor | 0.0229 | 0.1086 | 0.1086 |
Brugia malayi | hypothetical protein | 0.0229 | 0.1086 | 0.1086 |
Echinococcus multilocularis | g-protein coupled receptor | 0.0229 | 0.1086 | 0.1086 |
Echinococcus multilocularis | pyroglutamylated rfamide peptide receptor | 0.0229 | 0.1086 | 0.1086 |
Loa Loa (eye worm) | hypothetical protein | 0.0229 | 0.1086 | 0.1086 |
Echinococcus multilocularis | fmrfamide receptor | 0.0229 | 0.1086 | 0.1086 |
Schistosoma mansoni | peptide (FMRFamide/somatostatin)-like receptor | 0.0229 | 0.1086 | 0.1086 |
Brugia malayi | GnHR receptor homolog | 0.0229 | 0.1086 | 0.1086 |
Schistosoma mansoni | thyrotropin-releasing hormone receptor | 0.0229 | 0.1086 | 0.1086 |
Loa Loa (eye worm) | hypothetical protein | 0.0229 | 0.1086 | 0.1086 |
Echinococcus multilocularis | thyrotropin releasing hormone receptor | 0.0229 | 0.1086 | 0.1086 |
Schistosoma mansoni | ancient conserved domain protein 2 (cyclin m2) | 0.0229 | 0.1086 | 0.1086 |
Echinococcus granulosus | neuropeptides capa receptor | 0.0229 | 0.1086 | 0.1086 |
Loa Loa (eye worm) | G-protein coupled receptor | 0.0229 | 0.1086 | 0.1086 |
Loa Loa (eye worm) | hypothetical protein | 0.0229 | 0.1086 | 0.1086 |
Schistosoma mansoni | muscarinic acetylcholine (GAR) receptor | 0.0229 | 0.1086 | 0.1086 |
Schistosoma mansoni | rhodopsin-like orphan GPCR | 0.0229 | 0.1086 | 0.1086 |
Brugia malayi | ORL1-like opioid receptor | 0.0229 | 0.1086 | 0.1086 |
Trypanosoma brucei | dihydrofolate reductase-thymidylate synthase | 0.0794 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0229 | 0.1086 | 0.1086 |
Schistosoma mansoni | biogenic amine (dopamine) receptor | 0.0229 | 0.1086 | 0.1086 |
Echinococcus multilocularis | orexin receptor type 2 | 0.0229 | 0.1086 | 0.1086 |
Loa Loa (eye worm) | TYRA-2 protein | 0.0229 | 0.1086 | 0.1086 |
Schistosoma mansoni | amine GPCR | 0.0229 | 0.1086 | 0.1086 |
Echinococcus multilocularis | g protein coupled receptor | 0.0229 | 0.1086 | 0.1086 |
Brugia malayi | hypothetical protein | 0.0229 | 0.1086 | 0.1086 |
Brugia malayi | Dopamine receptor | 0.0229 | 0.1086 | 0.1086 |
Mycobacterium leprae | PROBABLE THYMIDYLATE SYNTHASE THYA (TS) (TSASE) | 0.0794 | 1 | 0.5 |
Echinococcus granulosus | thymidylate synthase | 0.0794 | 1 | 1 |
Echinococcus granulosus | g protein linked acetylcholine receptor gar 2a | 0.0229 | 0.1086 | 0.1086 |
Trypanosoma cruzi | dihydrofolate reductase-thymidylate synthase, putative | 0.0378 | 0.3427 | 0.3427 |
Brugia malayi | hypothetical protein | 0.0229 | 0.1086 | 0.1086 |
Echinococcus multilocularis | g protein linked acetylcholine receptor gar 2a | 0.0229 | 0.1086 | 0.1086 |
Schistosoma mansoni | opsin-like receptor | 0.0229 | 0.1086 | 0.1086 |
Loa Loa (eye worm) | melatonin receptor type 1A | 0.0229 | 0.1086 | 0.1086 |
Echinococcus multilocularis | g protein coupled receptor | 0.0229 | 0.1086 | 0.1086 |
Brugia malayi | putative neuropeptide receptor NPR1 | 0.0229 | 0.1086 | 0.1086 |
Schistosoma mansoni | histamine h1 receptor | 0.0229 | 0.1086 | 0.1086 |
Echinococcus multilocularis | neuropeptides capa receptor | 0.0229 | 0.1086 | 0.1086 |
Echinococcus multilocularis | tm gpcr rhodopsin gpcr rhodopsin superfamily | 0.0229 | 0.1086 | 0.1086 |
Schistosoma mansoni | histamine-responsive GPCR (AAF21638) | 0.0229 | 0.1086 | 0.1086 |
Echinococcus multilocularis | serotonin receptor | 0.0229 | 0.1086 | 0.1086 |
Schistosoma mansoni | biogenic amine receptor | 0.0229 | 0.1086 | 0.1086 |
Brugia malayi | metabotropic glutamate receptor subtype 5a (mGluR5a), putative | 0.0299 | 0.2183 | 0.2183 |
Loa Loa (eye worm) | hypothetical protein | 0.0229 | 0.1086 | 0.1086 |
Loa Loa (eye worm) | hypothetical protein | 0.0229 | 0.1086 | 0.1086 |
Echinococcus granulosus | rhodopsin orphan GPCR | 0.0229 | 0.1086 | 0.1086 |
Loa Loa (eye worm) | hypothetical protein | 0.0229 | 0.1086 | 0.1086 |
Schistosoma mansoni | metabotropic glutamate receptor 2 3 (mglur group 2) | 0.0375 | 0.3387 | 0.3387 |
Schistosoma mansoni | neuropeptide receptor | 0.0229 | 0.1086 | 0.1086 |
Echinococcus granulosus | sex peptide receptor | 0.0229 | 0.1086 | 0.1086 |
Echinococcus multilocularis | growth hormone secretagogue receptor type 1 | 0.0229 | 0.1086 | 0.1086 |
Schistosoma mansoni | rhodopsin-like orphan GPCR | 0.0229 | 0.1086 | 0.1086 |
Loa Loa (eye worm) | hypothetical protein | 0.0229 | 0.1086 | 0.1086 |
Echinococcus multilocularis | neuropeptide s receptor | 0.0229 | 0.1086 | 0.1086 |
Plasmodium vivax | bifunctional dihydrofolate reductase-thymidylate synthase, putative | 0.0794 | 1 | 0.5 |
Toxoplasma gondii | bifunctional dihydrofolate reductase-thymidylate synthase | 0.0794 | 1 | 1 |
Mycobacterium tuberculosis | Probable thymidylate synthase ThyA (ts) (TSASE) | 0.0794 | 1 | 1 |
Leishmania major | dihydrofolate reductase-thymidylate synthase | 0.0794 | 1 | 0.5 |
Echinococcus granulosus | metabotropic glutamate receptor 5 | 0.0406 | 0.3877 | 0.3877 |
Loa Loa (eye worm) | gonadotropin-releasing hormone receptor 2 | 0.0229 | 0.1086 | 0.1086 |
Loa Loa (eye worm) | hypothetical protein | 0.0229 | 0.1086 | 0.1086 |
Echinococcus granulosus | dro:myosuppressin receptor | 0.0229 | 0.1086 | 0.1086 |
Loa Loa (eye worm) | hypothetical protein | 0.0229 | 0.1086 | 0.1086 |
Loa Loa (eye worm) | 5-hydroxytryptamine 2C receptor | 0.0229 | 0.1086 | 0.1086 |
Loa Loa (eye worm) | hypothetical protein | 0.0229 | 0.1086 | 0.1086 |
Mycobacterium ulcerans | thymidylate synthase | 0.0794 | 1 | 0.5 |
Echinococcus granulosus | rhodopsin orphan GPCR | 0.0229 | 0.1086 | 0.1086 |
Trypanosoma cruzi | dihydrofolate reductase-thymidylate synthase | 0.0794 | 1 | 1 |
Echinococcus granulosus | 7TM GPCR rhodopsin | 0.0229 | 0.1086 | 0.1086 |
Echinococcus granulosus | fmrfamide receptor | 0.0229 | 0.1086 | 0.1086 |
Schistosoma mansoni | neuropeptide receptor | 0.0229 | 0.1086 | 0.1086 |
Schistosoma mansoni | myosin xvIII | 0.0229 | 0.1086 | 0.1086 |
Schistosoma mansoni | hypothetical protein | 0.0229 | 0.1086 | 0.1086 |
Loa Loa (eye worm) | hypothetical protein | 0.0229 | 0.1086 | 0.1086 |
Loa Loa (eye worm) | hypothetical protein | 0.0229 | 0.1086 | 0.1086 |
Loa Loa (eye worm) | hypothetical protein | 0.0229 | 0.1086 | 0.1086 |
Schistosoma mansoni | neuropeptide receptor | 0.0229 | 0.1086 | 0.1086 |
Loa Loa (eye worm) | hypothetical protein | 0.0229 | 0.1086 | 0.1086 |
Brugia malayi | neuropeptide F receptor | 0.0229 | 0.1086 | 0.1086 |
Loa Loa (eye worm) | hypothetical protein | 0.0229 | 0.1086 | 0.1086 |
Echinococcus multilocularis | G-protein coupled receptor, putative | 0.0229 | 0.1086 | 0.1086 |
Schistosoma mansoni | rhodopsin-like orphan GPCR | 0.0229 | 0.1086 | 0.1086 |
Loa Loa (eye worm) | hypothetical protein | 0.0229 | 0.1086 | 0.1086 |
Loa Loa (eye worm) | hypothetical protein | 0.0229 | 0.1086 | 0.1086 |
Loa Loa (eye worm) | hypothetical protein | 0.0229 | 0.1086 | 0.1086 |
Activity type | Activity value | Assay description | Source | Reference |
---|---|---|---|---|
I50 (binding) | = 4000 ng ml-1 | Inhibition of tryptophanyl tRNA synthetase isolated from Staphylococcus aureus | ChEMBL. | No reference |
MIC (functional) | > 64 ug ml-1 | Antibacterial activity against Staphylococcus aureus | ChEMBL. | No reference |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.