Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Onchocerca volvulus | Steroid hormone receptor family member cnr14 homolog | 0.007 | 0 | 0.5 |
Schistosoma mansoni | tar DNA-binding protein | 0.0076 | 1 | 1 |
Schistosoma mansoni | tar DNA-binding protein | 0.0076 | 1 | 1 |
Onchocerca volvulus | Protein ultraspiracle homolog | 0.007 | 0 | 0.5 |
Schistosoma mansoni | tar DNA-binding protein | 0.0076 | 1 | 1 |
Echinococcus multilocularis | tar DNA binding protein | 0.0076 | 1 | 1 |
Schistosoma mansoni | tar DNA-binding protein | 0.0076 | 1 | 1 |
Brugia malayi | TAR-binding protein | 0.0076 | 1 | 1 |
Onchocerca volvulus | 0.007 | 0 | 0.5 | |
Onchocerca volvulus | Bile acid receptor homolog | 0.007 | 0 | 0.5 |
Loa Loa (eye worm) | RNA binding protein | 0.0076 | 1 | 1 |
Loa Loa (eye worm) | RNA recognition domain-containing protein domain-containing protein | 0.0076 | 1 | 1 |
Echinococcus granulosus | tar DNA binding protein | 0.0076 | 1 | 1 |
Loa Loa (eye worm) | TAR-binding protein | 0.0076 | 1 | 1 |
Schistosoma mansoni | tar DNA-binding protein | 0.0076 | 1 | 1 |
Brugia malayi | RNA recognition motif domain containing protein | 0.0076 | 1 | 1 |
Activity type | Activity value | Assay description | Source | Reference |
---|---|---|---|---|
MIC (functional) | = 1 ug ml-1 | Antibacterial activity of compound was determined against Escherichia coli JM109 | ChEMBL. | 10360737 |
MIC (functional) | > 64 ug ml-1 | Antibacterial activity of compound was determined against Staphylococcus aureus 1538p | ChEMBL. | 10360737 |
MIC (functional) | > 64 ug ml-1 | Antibacterial activity of compound was determined against Streptococcus epidermidis 887E | ChEMBL. | 10360737 |
MIC (functional) | > 64 ug ml-1 | Antibacterial activity of compound was determined against Bacillus cereus ATCC 27348 | ChEMBL. | 10360737 |
MIC (functional) | > 64 ug ml-1 | Antibacterial activity of compound was determined against Salmonella typhimurium 14028 | ChEMBL. | 10360737 |
MIC (functional) | > 64 ug ml-1 | Antibacterial activity of compound was determined against Klebsiella pneumoniae 2011E | ChEMBL. | 10360737 |
MIC (functional) | > 64 ug ml-1 | Antibacterial activity of compound was determined against Klebsiella aerogenes 1976E | ChEMBL. | 10360737 |
MIC (functional) | > 64 ug ml-1 | Antibacterial activity of compound was determined against Pseudomonas aeruginosa 1912 | ChEMBL. | 10360737 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.
1 literature reference was collected for this gene.