Detailed information for compound 38654

Basic information

Technical information
  • Name: Unnamed compound
  • MW: 807.025 | Formula: C42H70N4O11
  • H donors: 4 H acceptors: 6 LogP: 3.8 Rotable bonds: 8
    Rule of 5 violations (Lipinski): 2
  • SMILES: CCOC(=O)c1ccc(nc1)N1CCC2(CC1)O[C@@H]1[C@@H](C)C(=O)O[C@H](CC)[C@@](C)(O)[C@@H]([C@H](NC[C@@H](C[C@](O2)(C)[C@@H]([C@H]1C)O[C@@H]1O[C@H](C)CC([C@H]1O)N(C)C)C)C)O
  • InChi: 1S/C42H70N4O11/c1-12-31-41(9,51)35(48)28(7)43-22-24(3)21-40(8)36(55-39-33(47)30(45(10)11)20-25(4)53-39)26(5)34(27(6)37(49)54-31)56-42(57-40)16-18-46(19-17-42)32-15-14-29(23-44-32)38(50)52-13-2/h14-15,23-28,30-31,33-36,39,43,47-48,51H,12-13,16-22H2,1-11H3/t24-,25-,26+,27-,28-,30?,31-,33-,34+,35-,36-,39+,40-,41-/m1/s1
  • InChiKey: FMNWOPLBEHPGGD-UZXOWIRASA-N  

Network

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Synonyms

No synonyms found for this compound

Targets

Known targets for this compound

No curated genes were found associated with this compound

Predicted pathogen targets for this compound

By orthology
No druggable targets predicted by orthology data
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity

Obtained from network model

Ranking Plot


Putative Targets List


Species Potential target Raw Global Species
Loa Loa (eye worm) hypothetical protein 0.0018 0.0019 0.0094
Schistosoma mansoni gcn5proteinral control of amino-acid synthesis 5-like 2 gcnl2 0.015 0.0423 0.0969
Onchocerca volvulus Nuclear receptor subfamily 6 group A member 1 homolog 0.0014 0.0007 0.0048
Echinococcus multilocularis Niemann Pick C1 protein 0.0302 0.0887 0.0887
Trypanosoma cruzi chloride channel protein, putative 0.0021 0.0026 0.0119
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0032 0.0062 0.0142
Loa Loa (eye worm) patched family protein 0.0018 0.0019 0.0094
Echinococcus multilocularis histone lysine N methyltransferase MLL3 0.0019 0.0022 0.0022
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0014 0.0007 0.0016
Schistosoma mansoni acetyl-CoA synthetase 0.0028 0.005 0.0116
Mycobacterium tuberculosis Hypoxic response protein 1 Hrp1 0.0021 0.0026 0.0083
Schistosoma mansoni Neurotrimin precursor (hNT) 0.0036 0.0073 0.0167
Plasmodium falciparum glutathione reductase 0.0039 0.0082 0.0148
Echinococcus granulosus defective proboscis extension response 0.0036 0.0073 0.0167
Loa Loa (eye worm) hypothetical protein 0.0014 0.0007 0.0034
Brugia malayi Immunoglobulin I-set domain containing protein 0.0016 0.0013 0.0064
Echinococcus granulosus roundabout 2 0.0058 0.0141 0.0324
Giardia lamblia GTP-binding nuclear protein RAN/TC4 0.0022 0.0031 0.016
Loa Loa (eye worm) D-ets-4 DNA binding domain-containing protein 0.0071 0.0181 0.0881
Echinococcus multilocularis ATP dependent DNA helicase Q1 0.0021 0.0026 0.0026
Brugia malayi photoreceptor-specific nuclear receptor 0.003 0.0056 0.0272
Loa Loa (eye worm) hypothetical protein 0.0018 0.0019 0.0094
Mycobacterium tuberculosis Carboxylesterase LipT 0.0057 0.0139 0.0509
Plasmodium vivax histone deacetylase 1, putative 0.0561 0.1678 0.309
Toxoplasma gondii thioredoxin reductase 0.0039 0.0082 0.0148
Brugia malayi Nuclear hormone receptor family member nhr-3 0.003 0.0056 0.0272
Leishmania major cell division related protein kinase 2,cdc2-related kinase 0.0049 0.0114 0.0549
Entamoeba histolytica hypothetical protein 0.0189 0.0542 0.3225
Schistosoma mansoni nephrin 0.0022 0.0032 0.0073
Schistosoma mansoni septate junction protein 0.0022 0.0032 0.0073
Trypanosoma cruzi FHA domain containing protein, putative 0.0031 0.0057 0.0271
Onchocerca volvulus 0.0018 0.0019 0.0131
Brugia malayi CHE-14 protein 0.013 0.036 0.1751
Trichomonas vaginalis conserved hypothetical protein 0.0031 0.0057 0.0331
Echinococcus granulosus Niemann Pick C1 protein 0.0431 0.1283 0.2941
Echinococcus multilocularis phd:f box containing protein 0.0016 0.0013 0.0013
Trichomonas vaginalis casein kinase II beta chain, putative 0.0038 0.0079 0.0463
Toxoplasma gondii flap structure-specific endonuclease 1, putative 0.0054 0.0129 0.0234
Plasmodium vivax patched family protein, putative 0.0018 0.0019 0.0032
Echinococcus granulosus dna polymerase eta 0.0136 0.0378 0.0867
Loa Loa (eye worm) hypothetical protein 0.0048 0.0111 0.054
Entamoeba histolytica protein kinase domain containing protein 0.0189 0.0542 0.3225
Echinococcus granulosus H:Cl exchange transporter 4 0.0021 0.0026 0.006
Echinococcus granulosus bloom syndrome protein 0.0021 0.0026 0.006
Loa Loa (eye worm) jmjC domain-containing protein 0.0016 0.0013 0.0063
Onchocerca volvulus Nuclear receptor subfamily 6 group A member 1 homolog 0.0014 0.0007 0.0048
Echinococcus granulosus sterol regulatory element binding protein 0.013 0.036 0.0824
Plasmodium vivax casein kinase II beta chain, putative 0.0038 0.0079 0.0143
Brugia malayi EST embl|AI107989|AI107989 comes from the 3' UTR, putative 0.0236 0.0685 0.3339
Trichomonas vaginalis CAMK family protein kinase 0.0022 0.0029 0.0165
Schistosoma mansoni retinoic acid receptor RXR 0.003 0.0056 0.0128
Echinococcus multilocularis histone deacetylase 1 0.0561 0.1678 0.1678
Trichomonas vaginalis casein kinase II beta chain, putative 0.0038 0.0079 0.0463
Schistosoma mansoni nuclear receptor 0.0014 0.0007 0.0016
Loa Loa (eye worm) hypothetical protein 0.0018 0.0019 0.0094
Plasmodium vivax dihydrolipoyl dehydrogenase, mitochondrial, putative 0.0013 0.0004 0.0005
Echinococcus multilocularis aurora kinase A 0.0169 0.0479 0.0479
Plasmodium vivax protein kinase Crk2 0.0049 0.0114 0.0208
Echinococcus granulosus importin subunit beta 1 0.003 0.0056 0.0127
Echinococcus granulosus peroxidasin 0.0022 0.0032 0.0073
Plasmodium falciparum protein MAM3, putative 0.0021 0.0026 0.0045
Wolbachia endosymbiont of Brugia malayi Mg/Co/Ni transporter MgtE 0.0021 0.0026 0.0425
Schistosoma mansoni defective proboscis extension response (dpr)-related 0.0036 0.0073 0.0167
Leishmania major acetoin dehydrogenase e3 component-like protein 0.0013 0.0004 0.0014
Trypanosoma cruzi hypothetical protein, conserved 0.0031 0.0057 0.0271
Plasmodium falciparum serine/threonine protein kinase, putative 0.0169 0.0479 0.088
Entamoeba histolytica Flap nuclease, putative 0.0054 0.0129 0.0757
Entamoeba histolytica acyl-CoA synthetase, putative 0.0097 0.026 0.1542
Leishmania major DNA polymerase eta, putative 0.0136 0.0378 0.1836
Trypanosoma brucei DNA polymerase kappa, putative 0.0163 0.0461 0.2241
Schistosoma mansoni cpg binding protein 0.0062 0.0152 0.0348
Trichomonas vaginalis glucosylceramidase, putative 0.0166 0.0472 0.2808
Loa Loa (eye worm) immunoglobulin I-set domain-containing protein 0.0022 0.0032 0.0155
Echinococcus granulosus 5' AMP activated protein kinase subunit gamma 0.0228 0.0661 0.1515
Echinococcus granulosus 6 phosphofructokinase 0.0113 0.0308 0.0706
Trichomonas vaginalis conserved hypothetical protein 0.0013 0.0004 0.0012
Trypanosoma cruzi CMGC/DYRK protein kinase, putative 0.0189 0.0542 0.2636
Schistosoma mansoni protein kinase subunit beta 0.0014 0.0006 0.0014
Trypanosoma cruzi trypanothione reductase, putative 0.0039 0.0082 0.0392
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0286 0.0839 0.4994
Echinococcus multilocularis dnaJ subfamily B 0.083 0.2503 0.2503
Brugia malayi Immunoglobulin I-set domain containing protein 0.0022 0.0032 0.0155
Mycobacterium leprae PROBABLE FATTY-ACID-CoA LIGASE FADD2 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) 0.0097 0.026 0.0889
Echinococcus granulosus intestinal type alkaline phosphatase 0.0169 0.0479 0.1098
Trypanosoma brucei Voltage-gated Chloride channel Like 3 0.0021 0.0026 0.0119
Echinococcus granulosus dna polymerase kappa 0.0163 0.0461 0.1058
Brugia malayi Ubiquitin carboxyl-terminal hydrolase family protein 0.0016 0.0011 0.0055
Loa Loa (eye worm) hypothetical protein 0.0016 0.0013 0.0063
Schistosoma mansoni cell adhesion molecule 0.0022 0.0032 0.0073
Brugia malayi Immunoglobulin I-set domain containing protein 0.0524 0.1566 0.763
Loa Loa (eye worm) GTP-binding regulatory protein Gs alpha-S chain 0.0047 0.0107 0.0521
Leishmania major long-chain-fatty-acid-CoA ligase, putative 0.0028 0.005 0.0238
Brugia malayi jmjC domain containing protein 0.0016 0.0013 0.0063
Entamoeba histolytica Niemann-Pick C1 protein, putative 0.0302 0.0887 0.5279
Echinococcus granulosus thyroid hormone receptor alpha 0.0014 0.0007 0.0016
Loa Loa (eye worm) hypothetical protein 0.0014 0.0007 0.0034
Loa Loa (eye worm) hypothetical protein 0.0058 0.0141 0.0689
Brugia malayi Patched family protein 0.0018 0.0019 0.0094
Schistosoma mansoni serine/threonine protein kinase 0.0049 0.0114 0.0262
Loa Loa (eye worm) acetylcholinesterase 1 0.034 0.1004 0.4891
Echinococcus granulosus roundabout 2 0.0022 0.0032 0.0073
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0286 0.0839 0.4994
Trypanosoma cruzi importin beta-1 subunit, putative 0.0024 0.0038 0.0178
Schistosoma mansoni hypothetical protein 0.0322 0.095 0.2176
Trichomonas vaginalis CAMK family protein kinase 0.0048 0.0111 0.0652
Onchocerca volvulus 0.0157 0.0442 0.3027
Schistosoma mansoni histone deacetylase hda2 0.0696 0.2091 0.4794
Trypanosoma brucei DNA polymerase kappa, putative 0.0163 0.0461 0.2241
Plasmodium falciparum NIMA related kinase 2 0.0022 0.0029 0.0051
Echinococcus multilocularis basement membrane specific heparan sulfate 0.0036 0.0073 0.0073
Loa Loa (eye worm) carboxylesterase 0.0057 0.0139 0.0678
Plasmodium falciparum chorismate synthase 0.1786 0.5428 1
Toxoplasma gondii GTP-binding nuclear protein ran/tc4 0.0022 0.0031 0.0055
Trichomonas vaginalis CAMK family protein kinase 0.0048 0.0111 0.0652
Brugia malayi histone deacetylase 1 (HD1) 0.0561 0.1678 0.8176
Leishmania major guanosine monophosphate reductase 0.0021 0.0026 0.0119
Echinococcus granulosus 5' AMP activated protein kinase subunit beta 1 0.0059 0.0145 0.0332
Trichomonas vaginalis conserved hypothetical protein 0.0013 0.0004 0.0012
Echinococcus multilocularis FTZ F1 alpha 0.003 0.0056 0.0056
Trichomonas vaginalis casein kinase II beta chain, putative 0.0038 0.0079 0.0463
Brugia malayi acetyltransferase, GNAT family protein 0.015 0.0423 0.206
Trichomonas vaginalis CAMK family protein kinase 0.0048 0.0111 0.0652
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0286 0.0839 0.4994
Trypanosoma brucei mitochondrial DNA polymerase beta-PAK 0.0147 0.0413 0.2003
Schistosoma mansoni titin 0.0022 0.0032 0.0073
Trichomonas vaginalis DNA helicase recq1, putative 0.0021 0.0026 0.0146
Mycobacterium tuberculosis 3-phosphoshikimate 1-carboxyvinyltransferase AroA (5-enolpyruvylshikimate-3-phosphate synthase) (EPSP synthase) (EPSPS) 0.0114 0.0313 0.1166
Leishmania major DNA polymerase eta, putative 0.006 0.0148 0.0712
Echinococcus multilocularis mixed lineage leukemia protein mll 0.0016 0.0011 0.0011
Trichomonas vaginalis phosphofructokinase, putative 0.0113 0.0308 0.1827
Toxoplasma gondii ck2 beta subunit 0.0038 0.0079 0.0143
Echinococcus granulosus hemicentin 1 0.0022 0.0032 0.0073
Trichomonas vaginalis DNA helicase recq, putative 0.0021 0.0026 0.0146
Echinococcus multilocularis histone deacetylase 7 0.0683 0.2053 0.2053
Loa Loa (eye worm) AMP-binding enzyme family protein 0.0028 0.005 0.0245
Brugia malayi ImpB/MucB/SamB family protein 0.0109 0.0297 0.1449
Mycobacterium tuberculosis Probable inosine-5'-monophosphate dehydrogenase GuaB2 (imp dehydrogenase) (inosinic acid dehydrogenase) (inosinate dehydrogenase 0.0021 0.0026 0.0083
Loa Loa (eye worm) steroid hormone receptor 0.003 0.0056 0.0272
Loa Loa (eye worm) carboxylesterase 0.034 0.1004 0.4891
Mycobacterium ulcerans phenyloxazoline synthase MbtB 0.0028 0.005 0.0085
Echinococcus multilocularis protein kinase shaggy 0.0051 0.0119 0.0119
Chlamydia trachomatis dehyroquinate synthase 0.0114 0.0313 0.057
Schistosoma mansoni FTZ-F1 nuclear receptor-like protein 0.003 0.0056 0.0128
Echinococcus granulosus inosine 5' monophosphate dehydrogenase 2 0.0021 0.0026 0.006
Toxoplasma gondii histone deacetylase HDAC1 0.0683 0.2053 0.378
Entamoeba histolytica hypothetical protein 0.0031 0.0057 0.0331
Brugia malayi jmjC domain containing protein 0.0016 0.0013 0.0063
Brugia malayi Histone deacetylase 1 0.0561 0.1678 0.8176
Brugia malayi hypothetical protein 0.0057 0.0139 0.0678
Echinococcus multilocularis GPCR, family 2 0.0082 0.0214 0.0214
Loa Loa (eye worm) hypothetical protein 0.0016 0.0012 0.0059
Loa Loa (eye worm) hypothetical protein 0.0044 0.0098 0.0476
Trypanosoma brucei DNA polymerase IV, putative 0.015 0.0421 0.2043
Schistosoma mansoni serine/threonine protein kinase 0.0236 0.0685 0.1571
Onchocerca volvulus 0.0057 0.0139 0.0952
Brugia malayi Patched family protein 0.0018 0.0019 0.0094
Echinococcus multilocularis gcn5proteinral control of amino acid synthesis 0.015 0.0423 0.0423
Toxoplasma gondii AMP-binding enzyme domain-containing protein 0.0028 0.005 0.009
Brugia malayi glutathione reductase 0.0039 0.0082 0.04
Loa Loa (eye worm) hypothetical protein 0.0014 0.0007 0.0034
Mycobacterium tuberculosis Conserved protein 0.0021 0.0026 0.0083
Plasmodium vivax serine/threonine protein kinase 6, putative 0.0169 0.0479 0.088
Loa Loa (eye worm) glutaminase 2 0.0552 0.1652 0.8046
Mycobacterium tuberculosis Probable NADH dehydrogenase Ndh 0.0089 0.0234 0.0869
Trichomonas vaginalis phosphofructokinase, putative 0.003 0.0056 0.0326
Toxoplasma gondii HEAT repeat-containing protein 0.003 0.0056 0.0099
Trichomonas vaginalis casein kinase II beta chain, putative 0.0038 0.0079 0.0463
Schistosoma mansoni tyrosine kinase 0.0027 0.0046 0.0105
Trichomonas vaginalis helicase, putative 0.0013 0.0004 0.0012
Mycobacterium leprae POSSIBLE O-SUCCINYLBENZOIC ACID--CoA LIGASE MENE (OSB-CoA SYNTHETASE) (O-SUCCINYLBENZOATE-CoA SYNTHASE) 0.0028 0.005 0.0093
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0013 0.0004 0.0014
Brugia malayi cell division control protein 2 homolog 0.0049 0.0114 0.0556
Loa Loa (eye worm) hypothetical protein 0.0051 0.012 0.0583
Schistosoma mansoni topbp1 0.0031 0.0057 0.0131
Loa Loa (eye worm) hypothetical protein 0.04 0.1187 0.5784
Brugia malayi Patched family protein 0.0018 0.0019 0.0094
Loa Loa (eye worm) histone deacetylase 1 0.0561 0.1678 0.8176
Loa Loa (eye worm) hypothetical protein 0.0018 0.0019 0.0094
Loa Loa (eye worm) runx1 0.0054 0.013 0.0632
Schistosoma mansoni serine/threonine protein kinase 0.0189 0.0542 0.1243
Mycobacterium tuberculosis Peptide synthetase MbtE (peptide synthase) 0.0028 0.005 0.0175
Loa Loa (eye worm) hypothetical protein 0.0014 0.0007 0.0034
Mycobacterium ulcerans long-chain-acyl-CoA synthetase 0.0028 0.005 0.0085
Schistosoma mansoni acetylcholinesterase 0.0057 0.0139 0.0319
Echinococcus granulosus Immunoglobulin 0.0036 0.0073 0.0167
Loa Loa (eye worm) hypothetical protein 0.0018 0.0019 0.0094
Loa Loa (eye worm) apoptosis regulator protein 0.0086 0.0226 0.11
Brugia malayi TAR-binding protein 0.0136 0.038 0.1852
Toxoplasma gondii histone lysine methyltransferase SET1 0.0115 0.0316 0.0579
Loa Loa (eye worm) carboxylesterase 0.0057 0.0139 0.0678
Brugia malayi Nuclear hormone receptor-like 1 0.0016 0.0012 0.0059
Entamoeba histolytica phosphofructokinase, putative 0.0113 0.0308 0.1827
Loa Loa (eye worm) hypothetical protein 0.0022 0.0032 0.0155
Brugia malayi Fibronectin type III domain containing protein 0.0036 0.0073 0.0355
Echinococcus granulosus ubiquitin carboxyl terminal hydrolase 8 0.0039 0.0082 0.0187
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.003 0.0056 0.0056
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0047 0.0107 0.0107
Echinococcus multilocularis protein patched 0.013 0.036 0.036
Trypanosoma brucei importin beta-1 subunit, putative 0.003 0.0056 0.0263
Echinococcus multilocularis Peptidase C19, ubiquitin carboxyl terminal hydrolase 2 0.0039 0.0082 0.0082
Echinococcus granulosus Nuclear hormone receptor family member nhr 41 0.003 0.0056 0.0128
Wolbachia endosymbiont of Brugia malayi Mg2+/Co2+ transporter 0.0021 0.0026 0.0425
Loa Loa (eye worm) hypothetical protein 0.0016 0.0012 0.0059
Trichomonas vaginalis conserved hypothetical protein 0.0031 0.0057 0.0331
Mycobacterium tuberculosis Peptide synthetase MbtF (peptide synthase) 0.0028 0.005 0.0175
Leishmania major apurinic/apyrimidinic endonuclease-redox protein 0.0019 0.0023 0.0103
Loa Loa (eye worm) hypothetical protein 0.0018 0.0019 0.0094
Brugia malayi O-Glycosyl hydrolase family 30 protein 0.0254 0.0739 0.3602
Schistosoma mansoni 6-phosphofructokinase 0.0113 0.0308 0.0706
Echinococcus multilocularis hepatocyte nuclear factor 4 alpha 0.003 0.0056 0.0056
Brugia malayi Histone deacetylase family protein 0.0683 0.2053 1
Plasmodium falciparum replication factor C subunit 1, putative 0.0031 0.0057 0.0102
Schistosoma mansoni alkaline phosphatase 0.0169 0.0479 0.1098
Brugia malayi AMP-binding enzyme family protein 0.0028 0.005 0.0245
Brugia malayi hypothetical protein 0.0018 0.0019 0.0094
Plasmodium falciparum ADP-dependent DNA helicase RecQ 0.0021 0.0026 0.0045
Trypanosoma brucei DNA polymerase eta, putative 0.0136 0.0378 0.1836
Echinococcus multilocularis flap endonuclease 1 0.0054 0.0129 0.0129
Echinococcus granulosus neuroglian 0.0022 0.0032 0.0073
Loa Loa (eye worm) hypothetical protein 0.0611 0.1834 0.8934
Brugia malayi Niemann-Pick C1 protein precursor 0.0302 0.0887 0.432
Brugia malayi conserved hypotetical protein 0.0014 0.0007 0.0034
Echinococcus multilocularis nuclear receptor nhr 48 0.0014 0.0007 0.0007
Onchocerca volvulus 0.0018 0.0019 0.0131
Mycobacterium ulcerans inosine 5'-monophosphate dehydrogenase 0.0021 0.0026 0.004
Toxoplasma gondii ImpB/MucB/SamB family protein 0.006 0.0148 0.0269
Leishmania major DNA polymerase kappa, putative 0.0034 0.0067 0.0318
Onchocerca volvulus 0.0032 0.0062 0.0423
Trichomonas vaginalis CAMK family protein kinase 0.0048 0.0111 0.0652
Schistosoma mansoni BC026374 protein (S09 family) 0.0057 0.0139 0.0319
Loa Loa (eye worm) hypothetical protein 0.0073 0.0185 0.0902
Mycobacterium ulcerans acyl-CoA synthetase 0.0028 0.005 0.0085
Trichomonas vaginalis histone deacetylase, putative 0.0561 0.1678 1
Brugia malayi jmjC domain containing protein 0.0061 0.015 0.0729
Loa Loa (eye worm) hypothetical protein 0.0032 0.0062 0.0301
Brugia malayi F/Y-rich N-terminus family protein 0.0019 0.0021 0.0103
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD3 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0069 0.0173 0.0637
Plasmodium vivax GTP-binding nuclear protein RAN/TC4, putative 0.0022 0.0031 0.0055
Trypanosoma cruzi JmjC domain, hydroxylase, putative 0.0016 0.0013 0.0055
Schistosoma mansoni steroid hormone receptor ad4bp 0.003 0.0056 0.0128
Schistosoma mansoni ap endonuclease 0.0019 0.0023 0.0052
Leishmania major protein kinase, putative 0.0022 0.0029 0.0135
Schistosoma mansoni septate junction protein 0.0022 0.0032 0.0073
Onchocerca volvulus 0.0058 0.0142 0.0968
Echinococcus multilocularis Nuclear hormone receptor family member nhr 41 0.003 0.0056 0.0056
Brugia malayi hypothetical protein 0.0014 0.0007 0.0034
Echinococcus multilocularis DNA (apurinic or apyrimidinic site) lyase 0.0019 0.0023 0.0023
Trichomonas vaginalis Importin beta-1 subunit, putative 0.0024 0.0038 0.0218
Echinococcus multilocularis 5' AMP activated protein kinase subunit beta 1 0.0059 0.0145 0.0145
Echinococcus granulosus cyclin dependent kinase 0.0049 0.0114 0.0262
Loa Loa (eye worm) ATP-dependent DNA helicase 0.0021 0.0026 0.0127
Entamoeba histolytica serine/threonine- protein kinase 6, putative 0.0169 0.0479 0.2849
Brugia malayi putative serine/threonine kinase SADA gamma 0.0048 0.0111 0.054
Trypanosoma cruzi trypanothione reductase, putative 0.0013 0.0004 0.0014
Plasmodium falciparum ATP-dependent DNA helicase Q1 0.0021 0.0026 0.0045
Echinococcus multilocularis receptor type tyrosine protein phosphatase 0.0022 0.0032 0.0032
Giardia lamblia Manganese-dependent inorganic pyrophosphatase, putative 0.0021 0.0026 0.0129
Echinococcus multilocularis snurportin 1 0.0322 0.095 0.095
Toxoplasma gondii IMP dehydrogenas 0.0021 0.0026 0.0045
Echinococcus granulosus histone deacetylase 7 0.0683 0.2053 0.4706
Echinococcus multilocularis carboxylesterase 5A 0.034 0.1004 0.1004
Echinococcus granulosus serine:threonine kinase SAD 1 0.0048 0.0111 0.0254
Giardia lamblia Manganese-dependent inorganic pyrophosphatase, putative 0.0021 0.0026 0.0129
Brugia malayi hypothetical protein 0.0157 0.0442 0.2155
Leishmania major serine/threonine-protein kinase, putative 0.0022 0.0029 0.0135
Schistosoma mansoni glycogen synthase kinase 3-related (gsk3) (cmgc group III) 0.0051 0.0119 0.0273
Trichomonas vaginalis phosphofructokinase, putative 0.003 0.0056 0.0326
Echinococcus multilocularis dihydrolipoamide dehydrogenase 0.0013 0.0004 0.0004
Brugia malayi Carboxylesterase family protein 0.0057 0.0139 0.0678
Toxoplasma gondii cell-cycle-associated protein kinase GSK, putative 0.0051 0.0119 0.0216
Echinococcus multilocularis protein dispatched 1 0.0148 0.0416 0.0416
Loa Loa (eye worm) ubiquitin carboxyl-terminal hydrolase 0.0016 0.0011 0.0055
Mycobacterium tuberculosis Probable 6-phosphofructokinase PfkA (phosphohexokinase) (phosphofructokinase) 0.0113 0.0308 0.1145
Entamoeba histolytica protein kinase domain containing protein 0.0051 0.0119 0.07
Trypanosoma cruzi cdc2-related kinase 1 0.0049 0.0114 0.0549
Giardia lamblia Sgs1 DNA helicase, putative 0.0021 0.0026 0.0129
Echinococcus granulosus alkaline phosphatase 0.0169 0.0479 0.1098
Echinococcus multilocularis 6 phosphofructokinase 0.0113 0.0308 0.0308
Schistosoma mansoni nuclear receptor 2DBD-gamma 0.003 0.0056 0.0128
Loa Loa (eye worm) ubiquitin specific peptidase 39 0.0016 0.0011 0.0055
Brugia malayi Nuclear hormone receptor family member nhr-25 0.003 0.0056 0.0272
Loa Loa (eye worm) hypothetical protein 0.0129 0.0359 0.1748
Schistosoma mansoni glutaminase 0.0552 0.1652 0.3786
Echinococcus granulosus serine:threonine protein kinase 12 B 0.0169 0.0479 0.1099
Echinococcus multilocularis receptor type tyrosine protein phosphatase F 0.0022 0.0032 0.0032
Leishmania major GTP-binding protein, putative 0.0022 0.0031 0.0144
Loa Loa (eye worm) hypothetical protein 0.0016 0.0012 0.0059
Giardia lamblia Ubiquitin carboxyl-terminal hydrolase 4 0.0039 0.0082 0.0462
Trichomonas vaginalis antibiotic synthetase, putative 0.0028 0.005 0.0291
Schistosoma mansoni nuclear hormone receptor 0.003 0.0056 0.0128
Echinococcus granulosus roundabout 2 0.0022 0.0032 0.0073
Trichomonas vaginalis phosphofructokinase, putative 0.0113 0.0308 0.1827
Onchocerca volvulus 0.0018 0.0019 0.0131
Brugia malayi Patched family protein 0.0018 0.0019 0.0094
Brugia malayi N-terminal motif family protein 0.0185 0.0531 0.2585
Trichomonas vaginalis chromosome transmission fidelity factor, putative 0.0031 0.0057 0.0331
Mycobacterium tuberculosis NADPH-dependent mycothiol reductase Mtr 0.0039 0.0082 0.0295
Echinococcus multilocularis cpg binding protein 0.0062 0.0152 0.0152
Loa Loa (eye worm) hypothetical protein 0.0097 0.026 0.1267
Treponema pallidum P26 0.0014 0.0006 0.002
Echinococcus granulosus Protein patched homolog 1 0.013 0.036 0.0824
Echinococcus multilocularis thyroid hormone receptor alpha 0.003 0.0056 0.0056
Toxoplasma gondii histone deacetylase HDAC2 0.0561 0.1678 0.309
Leishmania major histone deacetylase, putative 0.0683 0.2053 1
Schistosoma mansoni cell adhesion molecule 0.0022 0.0032 0.0073
Chlamydia trachomatis fructose-6-phosphate phosphotransferase 0.003 0.0056 0.0096
Loa Loa (eye worm) hypothetical protein 0.0018 0.0019 0.0094
Entamoeba histolytica acyl-coA synthetase, putative 0.0097 0.026 0.1542
Leishmania major hypothetical protein, conserved 0.0016 0.0013 0.0055
Trichomonas vaginalis ap endonuclease, putative 0.0019 0.0023 0.0127
Mycobacterium ulcerans acyl-CoA synthetase 0.0028 0.005 0.0085
Loa Loa (eye worm) pre-SET domain-containing protein family protein 0.0217 0.0627 0.3055
Mycobacterium tuberculosis Probable fructose-bisphosphate aldolase Fba 0.014 0.0391 0.1459
Trypanosoma cruzi cdc2-related kinase 1 0.0049 0.0114 0.0549
Leishmania major inosine-5-monophosphate dehydrogenase 0.0021 0.0026 0.0119
Trichomonas vaginalis phosphofructokinase, putative 0.0113 0.0308 0.1827
Trypanosoma cruzi histone deacetylase 1, putative 0.0561 0.1678 0.8175
Toxoplasma gondii patched family protein 0.0018 0.0019 0.0032
Brugia malayi protein C24B5.3 0.0018 0.0019 0.0094
Schistosoma mansoni receptor tyrosine phosphatase type r2a 0.0022 0.0032 0.0073
Brugia malayi Muscleblind-like protein 0.0611 0.1834 0.8934
Trypanosoma brucei DNA polymerase kappa, putative 0.0123 0.0338 0.164
Echinococcus multilocularis expressed conserved protein 0.0284 0.0831 0.0831
Loa Loa (eye worm) nuclear hormone receptor family member nhr-41 0.003 0.0056 0.0272
Mycobacterium tuberculosis Dihydrolipoamide dehydrogenase LpdC (lipoamide reductase (NADH)) (lipoyl dehydrogenase) (dihydrolipoyl dehydrogenase) (diaphoras 0.0099 0.0265 0.0983
Trichomonas vaginalis casein kinase II beta chain, putative 0.0038 0.0079 0.0463
Echinococcus multilocularis Protein lozenge 0.0054 0.013 0.013
Toxoplasma gondii hypothetical protein 0.0014 0.0006 0.0008
Trypanosoma cruzi mitochondrial DNA polymerase beta, putative 0.031 0.0913 0.4441
Trichomonas vaginalis histone deacetylase 1, 2 ,3, putative 0.0561 0.1678 1
Schistosoma mansoni nuclear hormone receptor superfamily protein-related 0.0014 0.0007 0.0016
Trypanosoma cruzi mitochondrial DNA polymerase beta-PAK, putative 0.0053 0.0126 0.0606
Brugia malayi Immunoglobulin I-set domain containing protein 0.0017 0.0014 0.0069
Echinococcus granulosus u4:u6.u5 tri snrnp associated protein 2 0.0016 0.0011 0.0026
Trichomonas vaginalis casein kinase II beta chain, putative 0.0038 0.0079 0.0463
Brugia malayi glutaminase DH11.1 0.0552 0.1652 0.8046
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0013 0.0004 0.0014
Trypanosoma cruzi hypothetical protein, conserved 0.0034 0.0067 0.0318
Trypanosoma brucei Serine/threonine-protein kinase NEK16, putative 0.0022 0.0029 0.0135
Leishmania major dihydrolipoamide dehydrogenase, putative 0.0013 0.0004 0.0014
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD2 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0097 0.026 0.0965
Plasmodium vivax histone deacetylase, putative 0.0683 0.2053 0.378
Echinococcus granulosus ATP dependent DNA helicase Q1 0.0021 0.0026 0.006
Onchocerca volvulus Tyrosine kinase homolog 0.049 0.1462 1
Echinococcus multilocularis serine:threonine kinase SAD 1 0.0048 0.0111 0.0111
Plasmodium falciparum glycogen synthase kinase 3 0.0051 0.0119 0.0216
Giardia lamblia Fructose-bisphosphate aldolase 0.0286 0.0839 0.4986
Loa Loa (eye worm) hypothetical protein 0.0018 0.0019 0.0094
Mycobacterium ulcerans hypothetical protein 0.0021 0.0026 0.004
Trypanosoma brucei SNF1-related protein kinases, putative 0.0048 0.0111 0.0533
Brugia malayi Immunoglobulin I-set domain containing protein 0.0022 0.0032 0.0155
Echinococcus multilocularis sterol regulatory element binding protein 0.013 0.036 0.036
Trypanosoma cruzi inosine-5'-monophosphate dehydrogenase, putative 0.0021 0.0026 0.0119
Loa Loa (eye worm) hypothetical protein 0.0018 0.0019 0.0094
Plasmodium falciparum serine/threonine protein kinase KIN 0.0048 0.0111 0.0201
Trypanosoma brucei dihydrolipoamide dehydrogenase, point mutation 0.0013 0.0004 0.0014
Trypanosoma cruzi leucine rich repeat protein, putative 0.0014 0.0006 0.0022
Trypanosoma cruzi glycogen synthase kinase 3, putative 0.0051 0.0119 0.0572
Mycobacterium ulcerans acyl-CoA synthetase 0.0097 0.026 0.0472
Schistosoma mansoni tar DNA-binding protein 0.0136 0.038 0.0872
Trypanosoma cruzi PAB1-binding protein , putative 0.0051 0.012 0.0576
Trichomonas vaginalis casein kinase II beta chain, putative 0.0038 0.0079 0.0463
Schistosoma mansoni retinoid-x-receptor (RXR) 0.0016 0.0012 0.0028
Trichomonas vaginalis chromosome transmission fidelity factor, putative 0.0031 0.0057 0.0331
Mycobacterium tuberculosis Probable reductase 0.0089 0.0234 0.0869
Onchocerca volvulus Protein patched homolog 0.0018 0.0019 0.0131
Loa Loa (eye worm) hypothetical protein 0.0014 0.0007 0.0034
Leishmania major ubiquitin hydrolase, putative,cysteine peptidase, Clan CA, family C19, putative 0.0016 0.0011 0.0047
Trypanosoma cruzi DNA polymerase kappa, putative 0.0163 0.0461 0.2241
Brugia malayi 5'-AMP-activated protein kinase, beta subunit, complex-interacting region containing protein 0.0111 0.0302 0.1472
Loa Loa (eye worm) hypothetical protein 0.0022 0.0032 0.0155
Echinococcus granulosus expressed conserved protein 0.0284 0.0831 0.1904
Brugia malayi Immunoglobulin I-set domain containing protein 0.0022 0.0032 0.0155
Echinococcus multilocularis Basic leucine zipper (bZIP) transcription 0.0042 0.0092 0.0092
Echinococcus granulosus JmjC domain containing protein 4 0.0016 0.0013 0.003
Loa Loa (eye worm) hypothetical protein 0.013 0.036 0.1751
Schistosoma mansoni AMP-activated protein kinase gamma regulatory subunit 0.0021 0.0026 0.006
Loa Loa (eye worm) hypothetical protein 0.0018 0.0019 0.0094
Echinococcus granulosus histone acetyltransferase KAT2B 0.0044 0.0098 0.0225
Schistosoma mansoni thyroid hormone receptor 0.003 0.0056 0.0128
Mycobacterium ulcerans NAD-dependent DNA ligase LigA 0.0031 0.0057 0.0097
Loa Loa (eye worm) hypothetical protein 0.0097 0.026 0.1267
Brugia malayi Nuclear hormone receptor family member nhr-19 0.003 0.0056 0.0272
Trypanosoma brucei histone deacetylase 3 0.0683 0.2053 1
Brugia malayi ATP-dependent DNA helicase, RecQ family protein 0.0021 0.0026 0.0127
Plasmodium vivax U4/U6.U5 tri-snRNP-associated protein 2, putative 0.0016 0.0011 0.0018
Entamoeba histolytica Ran family GTPase 0.0022 0.0031 0.0176
Schistosoma mansoni histone deacetylase 0.0561 0.1678 0.3847
Echinococcus multilocularis cadherin EGF LAG seven pass G type receptor 0.0082 0.0214 0.0214
Onchocerca volvulus 0.0016 0.0013 0.009
Mycobacterium ulcerans hypothetical protein 0.0097 0.026 0.0472
Schistosoma mansoni vesicular amine transporter 0.0036 0.0073 0.0167
Echinococcus granulosus tyrosine protein kinase otk 0.0022 0.0032 0.0073
Toxoplasma gondii histone deacetylase HDAC5 0.0283 0.0829 0.1524
Loa Loa (eye worm) hypothetical protein 0.0021 0.0026 0.0127
Echinococcus multilocularis muscleblind protein 1 0.0611 0.1834 0.1834
Trypanosoma brucei inosine-5'-monophosphate dehydrogenase 0.0021 0.0026 0.0119
Entamoeba histolytica fructose-1,6-bisphosphate aldolase, putative 0.0286 0.0839 0.4994
Brugia malayi hypothetical protein 0.0044 0.0098 0.0476
Echinococcus granulosus glycogen synthase kinase 3 beta 0.0051 0.0119 0.0273
Loa Loa (eye worm) hypothetical protein 0.0014 0.0007 0.0034
Trypanosoma cruzi PAB1-binding protein , putative 0.0051 0.012 0.0576
Trypanosoma cruzi 5'-AMP-activated protein kinase subunit beta, putative 0.0111 0.0302 0.1465
Loa Loa (eye worm) glutathione reductase 0.0039 0.0082 0.04
Entamoeba histolytica ubiquitin carboxyl-terminal hydrolase domain containing protein 0.0039 0.0082 0.0478
Schistosoma mansoni apoptosis regulator bax 0.0086 0.0226 0.0518
Loa Loa (eye worm) chloride channel protein 7 0.0021 0.0026 0.0127
Trichomonas vaginalis CAMK family protein kinase 0.0048 0.0111 0.0652
Trypanosoma brucei CMGC/DYRK protein kinase, putative 0.0189 0.0542 0.2636
Trypanosoma cruzi GMP reductase 0.0021 0.0026 0.0119
Echinococcus granulosus histone deacetylase 8 0.0283 0.0829 0.1899
Toxoplasma gondii glycogen synthase, putative 0.0014 0.0006 0.0008
Loa Loa (eye worm) thioredoxin reductase 0.0039 0.0082 0.04
Onchocerca volvulus 0.0057 0.0139 0.0952
Schistosoma mansoni jumonji/arid domain-containing protein 0.0064 0.016 0.0366
Trypanosoma brucei unspecified product 0.0075 0.0194 0.0936
Brugia malayi Nuclear hormone receptor family member nhr-1 0.003 0.0056 0.0272
Plasmodium falciparum casein kinase II beta chain 0.0038 0.0079 0.0143
Trypanosoma brucei flap endonuclease-1 (FEN-1), putative 0.0054 0.0129 0.0619
Loa Loa (eye worm) hypothetical protein 0.003 0.0056 0.0272
Loa Loa (eye worm) hypothetical protein 0.0014 0.0007 0.0034
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0016 0.0011 0.0057
Echinococcus granulosus FTZ F1 alpha 0.003 0.0056 0.0128
Onchocerca volvulus Alicorn homolog 0.0097 0.0259 0.1773
Schistosoma mansoni lozenge 0.0054 0.013 0.0297
Plasmodium falciparum glutathione reductase 0.0013 0.0004 0.0005
Echinococcus multilocularis cyclin dependent kinase 5 0.0049 0.0114 0.0114
Trypanosoma brucei hypothetical protein, conserved 0.0034 0.0067 0.0318
Brugia malayi Patched family protein 0.0018 0.0019 0.0094
Echinococcus multilocularis histone deacetylase 6 0.0696 0.2091 0.2091
Echinococcus multilocularis importin subunit beta 1 0.003 0.0056 0.0056
Giardia lamblia 5-AMP-activated protein kinase, beta-1 subunit 0.0111 0.0302 0.1778
Echinococcus granulosus GPCR family 2 0.0082 0.0214 0.049
Brugia malayi ATP dependent DNA ligase C terminal region family protein 0.0031 0.0057 0.0279
Loa Loa (eye worm) hypothetical protein 0.0031 0.0057 0.0279
Brugia malayi AMP-binding enzyme family protein 0.0028 0.005 0.0245
Trypanosoma cruzi Serine/threonine-protein kinase NEK11, putative 0.0022 0.0029 0.0135
Mycobacterium tuberculosis Probable soluble pyridine nucleotide transhydrogenase SthA (STH) (NAD(P)(+) transhydrogenase [B-specific]) (nicotinamide nucleot 0.0013 0.0004 0.0002
Leishmania major protein kinase ck2 regulatory subunit, putative 0.0038 0.0079 0.0378
Schistosoma mansoni DNA helicase recq5 0.0021 0.0026 0.006
Loa Loa (eye worm) MH2 domain-containing protein 0.0124 0.0342 0.1665
Echinococcus granulosus twitchin 0.0052 0.0123 0.0282
Plasmodium vivax chorismate synthase 0.1786 0.5428 1
Echinococcus multilocularis Ataxin 2, N terminal,domain containing protein 0.0023 0.0033 0.0033
Trichomonas vaginalis phosphofructokinase, putative 0.003 0.0056 0.0326
Mycobacterium ulcerans acyl-CoA synthetase 0.0028 0.005 0.0085
Echinococcus granulosus Basic leucine zipper bZIP transcription 0.0042 0.0092 0.0211
Trypanosoma brucei importin beta-1 subunit, putative 0.003 0.0056 0.0263
Leishmania major 2-oxoglutarate dehydrogenase, e3 component, lipoamidedehydrogenase-like protein 0.0013 0.0004 0.0014
Treponema pallidum exodeoxyribonuclease (exoA) 0.0019 0.0023 0.0221
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0016 0.0011 0.0025
Chlamydia trachomatis fructose-6-phosphate phosphotransferase 0.003 0.0056 0.0096
Trichomonas vaginalis conserved hypothetical protein 0.0013 0.0004 0.0012
Brugia malayi 6-phosphofructokinase 0.0113 0.0308 0.15
Schistosoma mansoni jumonji/arid domain-containing protein 0.0064 0.016 0.0366
Brugia malayi exodeoxyribonuclease III family protein 0.0019 0.0023 0.0111
Echinococcus granulosus histone deacetylase 6 0.0696 0.2091 0.4794
Leishmania major DNA polymerase kappa, putative 0.0123 0.0338 0.164
Brugia malayi Peroxidasin 0.0022 0.0032 0.0155
Plasmodium falciparum lipid/sterol:H+ symporter 0.0018 0.0019 0.0032
Schistosoma mansoni transcription factor LCR-F1 0.0042 0.0092 0.0211
Echinococcus multilocularis BRCA1 associated protein 0.0013 0.0002 0.0002
Schistosoma mansoni nuclear receptor 0.0014 0.0007 0.0016
Echinococcus multilocularis dna polymerase kappa 0.0163 0.0461 0.0461
Trypanosoma cruzi SNF1-related protein kinase regulatory subunit beta, putative 0.0111 0.0302 0.1465
Schistosoma mansoni AMP-activated protein kinase gamma regulatory subunit 0.0021 0.0026 0.006
Loa Loa (eye worm) hypothetical protein 0.0016 0.0013 0.0063
Trichomonas vaginalis glutaminase, putative 0.0552 0.1652 0.984
Brugia malayi Ets-domain containing protein 0.0071 0.0181 0.0881
Brugia malayi Pre-SET motif family protein 0.0032 0.0062 0.0301
Schistosoma mansoni inosine-5-monophosphate dehydrogenase 0.0021 0.0026 0.006
Brugia malayi Nuclear hormone receptor family member nhr-40 0.003 0.0056 0.0272
Toxoplasma gondii histone deacetylase HDAC3 0.0561 0.1678 0.309
Echinococcus granulosus H:Cl exchange transporter 7 0.0021 0.0026 0.006
Loa Loa (eye worm) hypothetical protein 0.0057 0.0139 0.0678
Trichomonas vaginalis conserved hypothetical protein 0.013 0.036 0.2135
Schistosoma mansoni histone deacetylase hda2 0.0283 0.0829 0.1899
Toxoplasma gondii histone kinase SNF1, putative 0.0048 0.0111 0.0201
Trypanosoma brucei dihydrolipoamide dehydrogenase 0.0013 0.0004 0.0014
Schistosoma mansoni casein kinase II beta subunit 0.0038 0.0079 0.0182
Loa Loa (eye worm) hypothetical protein 0.003 0.0056 0.0272
Schistosoma mansoni protein kinase subunit beta 0.0059 0.0145 0.0332
Brugia malayi Nuclear hormone receptor family member nhr-19 0.003 0.0056 0.0272
Brugia malayi inosine-5'-monophosphate dehydrogenase family protein 0.0021 0.0026 0.0127
Schistosoma mansoni microtubule-associated protein tau 0.1438 0.4363 1
Brugia malayi Pax transcription activation domain interacting protein 0.0031 0.0057 0.0279
Schistosoma mansoni hypothetical protein 0.0177 0.0505 0.1157
Loa Loa (eye worm) hypothetical protein 0.0177 0.0505 0.2459
Echinococcus multilocularis intestinal type alkaline phosphatase 1 0.0169 0.0479 0.0479
Trichomonas vaginalis CAMK family protein kinase 0.0048 0.0111 0.0652
Toxoplasma gondii ImpB/MucB/SamB family protein 0.0034 0.0067 0.012
Plasmodium falciparum casein kinase II beta chain 0.0038 0.0079 0.0143
Trypanosoma brucei DNA polymerase kappa, putative 0.0163 0.0461 0.2241
Trypanosoma cruzi AMP-activated protein kinase, gamma regulatory subunit 0.0021 0.0026 0.0119
Echinococcus granulosus H:Cl exchange transporter 3 0.0021 0.0026 0.006
Mycobacterium ulcerans 6-phosphofructokinase 0.0113 0.0308 0.056
Echinococcus multilocularis 5' AMP activated protein kinase catalytic 0.0236 0.0685 0.0685
Trypanosoma cruzi mitochondrial DNA polymerase beta-PAK, putative 0.0044 0.0097 0.0463
Loa Loa (eye worm) patched family protein 0.0018 0.0019 0.0094
Brugia malayi Patched family protein 0.0018 0.0019 0.0094
Echinococcus multilocularis glycogen synthase kinase 3 beta 0.0051 0.0119 0.0119
Loa Loa (eye worm) hypothetical protein 0.0611 0.1834 0.8934
Brugia malayi Patched family protein 0.0018 0.0019 0.0094
Loa Loa (eye worm) RNA recognition domain-containing protein domain-containing protein 0.0136 0.038 0.1852
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0013 0.0004 0.0012
Leishmania major histone deacetylase, putative 0.0683 0.2053 1
Mycobacterium tuberculosis Conserved hypothetical protein 0.0163 0.0463 0.1731
Echinococcus granulosus retinoic acid receptor rxr beta a 0.003 0.0056 0.0128
Loa Loa (eye worm) TAR-binding protein 0.0136 0.038 0.1852
Leishmania major hypothetical protein, conserved 0.0021 0.0026 0.0119
Trichomonas vaginalis histone deacetylase, putative 0.0561 0.1678 1
Echinococcus multilocularis BC026374 protein (S09 family) 0.0057 0.0139 0.0139
Trypanosoma cruzi long-chain-fatty-acid-CoA ligase, putative 0.0028 0.005 0.0238
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0047 0.0107 0.0245
Brugia malayi AMP-binding enzyme family protein 0.0028 0.005 0.0245
Loa Loa (eye worm) hypothetical protein 0.0413 0.1226 0.5972
Trypanosoma brucei PAB1-binding protein , putative 0.0051 0.012 0.0576
Schistosoma mansoni nuclear hormone receptor nor-1/nor-2 0.003 0.0056 0.0128
Brugia malayi nuclear receptor RXR 0.0014 0.0007 0.0034
Mycobacterium leprae 3-dehydroquinate synthase AroB 0.0114 0.0313 0.1092
Schistosoma mansoni gliotactin 0.0057 0.0139 0.0319
Toxoplasma gondii ATP-dependent DNA helicase, RecQ family protein 0.0021 0.0026 0.0045
Schistosoma mansoni terminal deoxycytidyl transferase 0.0109 0.0297 0.0682
Loa Loa (eye worm) hypothetical protein 0.0018 0.0019 0.0094
Loa Loa (eye worm) hypothetical protein 0.0014 0.0007 0.0034
Loa Loa (eye worm) abnormal chemotaxis protein 14 0.013 0.036 0.1751
Trichomonas vaginalis mercuric reductase, putative 0.0013 0.0004 0.0017
Entamoeba histolytica protein kinase, putative 0.0169 0.0479 0.2849
Loa Loa (eye worm) ubiquitin carboxyl-terminal hydrolase 0.0016 0.0011 0.0055
Trypanosoma brucei AIR9-like protein 0.0014 0.0006 0.0022
Toxoplasma gondii histone lysine acetyltransferase GCN5-B 0.0044 0.0098 0.0178
Entamoeba histolytica acetyltransferase, GNAT family 0.004 0.0087 0.051
Echinococcus multilocularis peroxidasin 0.0022 0.0032 0.0032
Schistosoma mansoni brca1-associated protein (brap2) 0.0013 0.0002 0.0004
Mycobacterium ulcerans acetyl-CoA synthetase 0.0028 0.005 0.0085
Trichomonas vaginalis CAMK family protein kinase 0.0048 0.0111 0.0652
Trypanosoma cruzi NIMA-related kinase, putative 0.0022 0.0029 0.0135
Mycobacterium ulcerans long-chain-fatty-acid--CoA ligase 0.0097 0.026 0.0472
Loa Loa (eye worm) nuclear hormone receptor 0.0014 0.0007 0.0034
Trichomonas vaginalis AGC family protein kinase 0.0169 0.0479 0.2849
Echinococcus granulosus AMPK beta subunit 0.0111 0.0302 0.0692
Loa Loa (eye worm) glutaminase 0.0552 0.1652 0.8046
Trypanosoma brucei histone deacetylase 4 0.0683 0.2053 1
Entamoeba histolytica acyl-CoA synthetase, putative 0.0097 0.026 0.1542
Entamoeba histolytica exodeoxyribonuclease III, putative 0.0019 0.0023 0.0127
Entamoeba histolytica Activator 1 140 kDa subunit, putative 0.0031 0.0057 0.0331
Echinococcus multilocularis Immunoglobulin 0.0036 0.0073 0.0073
Loa Loa (eye worm) hypothetical protein 0.0016 0.0012 0.0059
Echinococcus multilocularis histone deacetylase 3 0.0561 0.1678 0.1678
Trypanosoma brucei histone deacetylase 1 0.0561 0.1678 0.8175
Echinococcus multilocularis serine:threonine protein kinase Nek1 0.0017 0.0016 0.0016
Onchocerca volvulus Protein patched homolog 0.0018 0.0019 0.0131
Onchocerca volvulus 0.0052 0.0122 0.0832
Onchocerca volvulus 0.0028 0.005 0.0345
Echinococcus multilocularis ubiquitin carboxyl terminal hydrolase 22 0.0016 0.0011 0.0011
Echinococcus multilocularis H(+):Cl() exchange transporter 7 0.0021 0.0026 0.0026
Mycobacterium ulcerans acyl-CoA synthetase 0.0028 0.005 0.0085
Schistosoma mansoni hypothetical protein 0.0082 0.0214 0.049
Echinococcus granulosus diuretic hormone 44 receptor GPRdih2 0.0082 0.0214 0.049
Loa Loa (eye worm) nuclear hormone receptor family member nhr-31 0.003 0.0056 0.0272
Brugia malayi Patched family protein 0.0018 0.0019 0.0094
Echinococcus multilocularis alkaline phosphatase 0.0169 0.0479 0.0479
Schistosoma mansoni ran 0.0022 0.0031 0.0072
Mycobacterium ulcerans DNA polymerase IV 0.0163 0.0461 0.0843
Schistosoma mansoni hepatocyte nuclear factor 4-alpha (hnf-4-alpha) 0.0014 0.0007 0.0016
Giardia lamblia Aurora kinase 0.0169 0.0479 0.2837
Echinococcus granulosus aurora kinase A 0.0169 0.0479 0.1099
Brugia malayi histone deacetylase 11 0.0283 0.0829 0.4036
Loa Loa (eye worm) hypothetical protein 0.0018 0.0019 0.0094
Trypanosoma cruzi histone deacetylase, putative 0.0283 0.0829 0.4032
Plasmodium vivax AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.0019 0.0023 0.0039
Schistosoma mansoni tar DNA-binding protein 0.0136 0.038 0.0872
Schistosoma mansoni hypothetical protein 0.0023 0.0033 0.0077
Schistosoma mansoni serine/threonine protein kinase 0.0048 0.0111 0.0254
Trichomonas vaginalis glucosylceramidase, putative 0.0166 0.0472 0.2808
Mycobacterium leprae POSSIBLE FATTY-ACID-CoA LIGASE FADD10 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) 0.0028 0.005 0.0093
Loa Loa (eye worm) hypothetical protein 0.0061 0.0149 0.0727
Wolbachia endosymbiont of Brugia malayi exonuclease III 0.0019 0.0023 0.0363
Trichomonas vaginalis glucosylceramidase, putative 0.0175 0.05 0.2972
Echinococcus granulosus nuclear receptor subfamily 4 group A 0.0014 0.0007 0.0016
Treponema pallidum Mg2+ transport protein (mgtE) 0.0021 0.0026 0.0259
Echinococcus granulosus ubiquitin specific protease 41 0.0039 0.0082 0.0187
Brugia malayi nuclear receptor NHR-88 0.0014 0.0007 0.0034
Onchocerca volvulus 0.0028 0.005 0.0345
Onchocerca volvulus Histone deacetylase 10 homolog 0.0283 0.0829 0.5669
Loa Loa (eye worm) hypothetical protein 0.0044 0.0098 0.0476
Brugia malayi chloride channel protein 7 0.0021 0.0026 0.0127
Echinococcus multilocularis histone deacetylase 6 0.0683 0.2053 0.2053
Brugia malayi Nuclear hormone receptor E75 0.0014 0.0007 0.0034
Brugia malayi Prion-like- 0.0022 0.0032 0.0155
Loa Loa (eye worm) hypothetical protein 0.0018 0.0019 0.0094
Brugia malayi hypothetical protein 0.0042 0.0092 0.0448
Echinococcus multilocularis dual specificity 0.0189 0.0542 0.0542
Plasmodium falciparum ataxin-2 like protein, putative 0.0051 0.012 0.0218
Onchocerca volvulus 0.0031 0.0057 0.0391
Mycobacterium tuberculosis Conserved hypothetical membrane protein 0.0021 0.0026 0.0083
Schistosoma mansoni neuroligin 3 (S09 family) 0.0057 0.0139 0.0319
Toxoplasma gondii patched family protein 0.0018 0.0019 0.0032
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0013 0.0004 0.0014
Trichomonas vaginalis RNA polymerase II ctd phosphatase, putative 0.0031 0.0057 0.0331
Loa Loa (eye worm) AUR protein kinase 0.0169 0.0479 0.2335
Schistosoma mansoni neurotracting/lsamp/neurotrimin/obcam related cell adhesion molecule 0.0022 0.0032 0.0073
Trichomonas vaginalis CAMK family protein kinase 0.0022 0.0029 0.0165
Schistosoma mansoni brca1-associated protein (brap2) 0.0013 0.0002 0.0004
Trichomonas vaginalis conserved hypothetical protein 0.0013 0.0004 0.0012
Mycobacterium tuberculosis Possible DNA-damage-inducible protein P DinP (DNA polymerase V) (pol IV 2) (DNA nucleotidyltransferase (DNA-directed)) 0.0123 0.0338 0.1259
Echinococcus multilocularis jumonji domain containing 1A 0.0016 0.0013 0.0013
Trypanosoma brucei Serine/threonine-protein kinase NEK11, putative 0.0022 0.0029 0.0135
Trypanosoma cruzi GMP reductase 0.0021 0.0026 0.0119
Trypanosoma cruzi DNA damage repair protein, putative 0.0034 0.0067 0.0318
Loa Loa (eye worm) histone deacetylase 0.0683 0.2053 1
Echinococcus multilocularis tyrosine protein kinase transmembrane receptor 0.0017 0.0014 0.0014
Chlamydia trachomatis GutQ/KpsF family sugar-phosphate isomerase 0.0021 0.0026 0.004
Mycobacterium ulcerans fructose-bisphosphate aldolase 0.014 0.0391 0.0713
Plasmodium vivax serine/threonine protein kinase KIN, putative 0.0048 0.0111 0.0201
Giardia lamblia Kinase, CMGC GSK 0.0051 0.0119 0.0684
Echinococcus multilocularis EGFP:Bcl2 fusion protein 0.0086 0.0226 0.0226
Trypanosoma brucei DNA polymerase IV, putative 0.0163 0.0461 0.2241
Mycobacterium ulcerans long-chain-fatty-acid-CoA ligase 0.0097 0.026 0.0472
Trichomonas vaginalis casein kinase II beta chain, putative 0.0038 0.0079 0.0463
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.003 0.0056 0.0272
Trypanosoma cruzi DNA polymerase kappa, putative 0.0163 0.0461 0.2241
Plasmodium vivax importin-beta 2, putative 0.003 0.0056 0.0099
Loa Loa (eye worm) hypothetical protein 0.0039 0.0082 0.0398
Schistosoma mansoni hypothetical protein 0.0042 0.0092 0.0211
Loa Loa (eye worm) nuclear hormone receptor family member nhr-1 0.003 0.0056 0.0272
Brugia malayi Csnk2b protein 0.0038 0.0079 0.0386
Echinococcus granulosus nibrin 0.0031 0.0057 0.0131
Echinococcus multilocularis hemicentin 1 0.0022 0.0032 0.0032
Onchocerca volvulus Glucosylceramidase homolog 0.0166 0.0472 0.3232
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0013 0.0004 0.0014
Trypanosoma cruzi DNA polymerase eta, putative 0.0136 0.0378 0.1836
Trichomonas vaginalis spcc417.12 protein, putative 0.0057 0.0139 0.082
Loa Loa (eye worm) CMGC/CDK/CDK5 protein kinase 0.0049 0.0114 0.0556
Schistosoma mansoni AMP-activated protein kinase gamma regulatory subunit 0.0021 0.0026 0.006
Trichomonas vaginalis CAMK family protein kinase 0.0048 0.0111 0.0652
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.003 0.0056 0.0272
Loa Loa (eye worm) hypothetical protein 0.0022 0.0032 0.0155
Trypanosoma brucei 5'-AMP-activated protein kinase subunit beta 0.0111 0.0302 0.1465
Entamoeba histolytica ubiquitin carboxyl-terminal hydrolase 5, putative 0.0016 0.0011 0.0057
Onchocerca volvulus 0.0247 0.0718 0.4914
Echinococcus multilocularis microtubule associated protein 2 0.1438 0.4363 0.4363
Schistosoma mansoni 3-dehydroquinate synthase 0.0114 0.0313 0.0719
Wolbachia endosymbiont of Brugia malayi NAD-dependent DNA ligase, Lig 0.0031 0.0057 0.1038
Schistosoma mansoni hypothetical protein 0.0082 0.0214 0.049
Echinococcus granulosus acetyl coenzyme A synthetase cytoplasmic 0.0028 0.005 0.0116
Mycobacterium ulcerans hypothetical protein 0.0163 0.0463 0.0846
Echinococcus granulosus COUP TF:Svp nuclear hormone receptor 0.003 0.0056 0.0128
Giardia lamblia Kinase, CMGC CDK 0.0049 0.0114 0.0656
Schistosoma mansoni bcl-2 homologous antagonist/killer (bak) 0.0086 0.0226 0.0518
Brugia malayi steroid hormone receptor 0.003 0.0056 0.0272
Echinococcus multilocularis family S9 non peptidase ue (S09 family) 0.0057 0.0139 0.0139
Trichomonas vaginalis glucosylceramidase, putative 0.0166 0.0472 0.2808
Trypanosoma brucei DNA polymerase kappa, putative 0.0089 0.0234 0.1135
Echinococcus multilocularis histone deacetylase 8 0.0283 0.0829 0.0829
Mycobacterium tuberculosis Probable oxidoreductase 0.0099 0.0265 0.0983
Trichomonas vaginalis histone deacetylase 1, 2 ,3, putative 0.0561 0.1678 1
Echinococcus granulosus 5'partial|histone lysine N methyltransferase SETDB2 0.003 0.0054 0.0125
Echinococcus granulosus histone acetyltransferase KAT2B 0.0146 0.041 0.094
Mycobacterium ulcerans UDP-N-acetylglucosamine 1-carboxyvinyltransferase 0.018 0.0513 0.0937
Echinococcus multilocularis muscleblind protein 0.0611 0.1834 0.1834
Onchocerca volvulus 0.0057 0.0139 0.0952
Mycobacterium leprae PROBABLE 6-PHOSPHOFRUCTOKINASE PFKA (PHOSPHOHEXOKINASE) (PHOSPHOFRUCTOKINASE) 0.0113 0.0308 0.1071
Plasmodium falciparum thioredoxin reductase 0.0039 0.0082 0.0148
Echinococcus granulosus tyrosine protein kinase transmembrane receptor 0.0017 0.0014 0.0033
Leishmania major hypothetical protein, conserved 0.0051 0.012 0.0576
Trichomonas vaginalis CMGC family protein kinase 0.0049 0.0114 0.0672
Brugia malayi hypothetical protein 0.0014 0.0007 0.0034
Loa Loa (eye worm) hypothetical protein 0.0031 0.0057 0.0279
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0013 0.0004 0.0012
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.0028 0.005 0.0245
Plasmodium vivax flap endonuclease 1, putative 0.0054 0.0129 0.0234
Mycobacterium ulcerans chorismate synthase 0.1786 0.5428 1
Onchocerca volvulus 0.0018 0.0019 0.0131
Trypanosoma cruzi ubiquitin carboxyl-terminal hydrolase, putative 0.0016 0.0011 0.0047
Trichomonas vaginalis CAMK family protein kinase 0.0048 0.0111 0.0652
Mycobacterium ulcerans carboxylesterase, LipT 0.0057 0.0139 0.0248
Loa Loa (eye worm) hypothetical protein 0.0036 0.0073 0.0355
Mycobacterium ulcerans exodeoxyribonuclease III protein XthA 0.0019 0.0023 0.0034
Plasmodium vivax thioredoxin reductase, putative 0.0039 0.0082 0.0148
Mycobacterium tuberculosis Conserved protein 0.0021 0.0026 0.0083
Loa Loa (eye worm) hypothetical protein 0.027 0.079 0.3847
Trypanosoma cruzi inosine-5'-monophosphate dehydrogenase, putative 0.0021 0.0026 0.0119
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0286 0.0839 0.4994
Schistosoma mansoni hypothetical protein 0.0086 0.0226 0.0518
Loa Loa (eye worm) hypothetical protein 0.0031 0.0057 0.0279
Schistosoma mansoni ubiquitin-specific peptidase 8 (C19 family) 0.0039 0.0082 0.0187
Trypanosoma cruzi protein kinase, putative 0.0017 0.0016 0.0071
Schistosoma mansoni hypothetical protein 0.0125 0.0345 0.0791
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0039 0.0082 0.0478
Loa Loa (eye worm) latrophilin receptor protein 2 0.0082 0.0214 0.1042
Plasmodium falciparum histone acetyltransferase GCN5 0.004 0.0087 0.0158
Leishmania major ubiquitin hydrolase, putative,cysteine peptidase, Clan CA, family C19, putative 0.0039 0.0082 0.039
Entamoeba histolytica hypothetical protein 0.0042 0.0092 0.0539
Loa Loa (eye worm) loechrig isoform VII 0.0228 0.0661 0.322
Brugia malayi 6-phosphofructokinase 0.0113 0.0308 0.1501
Trypanosoma brucei DNA polymerase IV, putative 0.0163 0.0461 0.2241
Trypanosoma brucei DNA damage repair protein, putative 0.0034 0.0067 0.0318
Toxoplasma gondii CBS domain-containing protein 0.0021 0.0026 0.0045
Loa Loa (eye worm) hypothetical protein 0.0018 0.0019 0.0094
Echinococcus granulosus ATP dependent DNA helicase Q5 0.0021 0.0026 0.006
Chlamydia trachomatis acylglycerophosphoethanolamine acyltransferase 0.0073 0.0185 0.0333
Toxoplasma gondii phosphofructokinase domain-containing protein 0.003 0.0056 0.0101
Giardia lamblia Hypothetical protein 0.0021 0.0026 0.0129
Trypanosoma brucei 5'-AMP-activated protein kinase catalytic subunit alpha, putative 0.0048 0.0111 0.0533
Schistosoma mansoni DNA polymerase eta 0.0136 0.0378 0.0867
Brugia malayi RNA binding protein 0.0136 0.038 0.1852
Echinococcus multilocularis 5' AMP activated protein kinase subunit gamma 0.0208 0.0598 0.0598
Schistosoma mansoni cpg binding protein 0.0062 0.0152 0.0348
Trypanosoma cruzi chloride channel protein, putative 0.0021 0.0026 0.0119
Chlamydia trachomatis chorismate synthase 0.1786 0.5428 1
Trypanosoma brucei Casein kinase II subunit beta, putative 0.0038 0.0079 0.0378
Echinococcus multilocularis Transcription factor, JmjC domain containing protein 0.0061 0.015 0.015
Toxoplasma gondii casein kinase ii regulatory subunit protein 0.0038 0.0079 0.0143
Plasmodium falciparum thioredoxin reductase 0.0013 0.0004 0.0005
Leishmania major mitochondrial DNA polymerase beta 0.031 0.0913 0.4441
Echinococcus multilocularis histone deacetylase 0.0683 0.2053 0.2053
Brugia malayi Nuclear hormone receptor family member nhr-49 0.003 0.0056 0.0272
Loa Loa (eye worm) immunoglobulin I-set domain-containing protein 0.0022 0.0032 0.0155
Entamoeba histolytica fructose-1,6-bisphosphate aldolase, putative 0.0286 0.0839 0.4994
Trichomonas vaginalis bromodomain-containing protein, putative 0.0044 0.0098 0.0577
Brugia malayi loechrig isoform VII 0.0228 0.0661 0.322
Leishmania major DNA polymerase kappa, putative,DNA polymerase IV, putative 0.0123 0.0338 0.164
Echinococcus multilocularis cyclin dependent kinase 5 activator 1 0.027 0.079 0.079
Schistosoma mansoni serine/threonine protein kinase 0.0016 0.0013 0.003
Plasmodium vivax DNA repair protein REV1, putative 0.0034 0.0067 0.012
Trichomonas vaginalis conserved hypothetical protein 0.0013 0.0004 0.0012
Giardia lamblia Kinase, CMGC GSK 0.0051 0.0119 0.0684
Brugia malayi AMP-binding enzyme family protein 0.0097 0.026 0.1267
Echinococcus multilocularis intestinal type alkaline phosphatase 0.0169 0.0479 0.0479
Brugia malayi hypothetical protein 0.0129 0.0359 0.1748
Loa Loa (eye worm) hypothetical protein 0.0088 0.0231 0.1125
Mycobacterium leprae PROBABLE NADH DEHYDROGENASE NDH 0.0089 0.0234 0.0792
Loa Loa (eye worm) hypothetical protein 0.003 0.0056 0.0272
Trypanosoma brucei ATP-dependent 6-phosphofructokinase, glycosomal 0.0113 0.0308 0.1493
Brugia malayi Patched family protein 0.0018 0.0019 0.0094
Trypanosoma brucei ubiquitin carboxyl-terminal hydrolase, putative 0.0016 0.0011 0.0047
Echinococcus multilocularis inosine 5' monophosphate dehydrogenase 2 0.0021 0.0026 0.0026
Brugia malayi Pre-SET motif family protein 0.0217 0.0627 0.3055
Trypanosoma brucei DNA polymerase kappa, putative 0.0163 0.0461 0.2241
Trichomonas vaginalis cat eye syndrome critical region protein 2, cscr2, putative 0.0044 0.0098 0.0577
Brugia malayi Nuclear hormone receptor-like 1 0.003 0.0056 0.0272
Loa Loa (eye worm) CAMK protein kinase 0.0016 0.0013 0.0064
Brugia malayi nuclear hormone receptor 0.0014 0.0007 0.0034
Plasmodium falciparum dihydrolipoyl dehydrogenase, mitochondrial 0.0013 0.0004 0.0005
Trypanosoma cruzi mitochondrial DNA polymerase beta, putative 0.031 0.0913 0.4441
Schistosoma mansoni hypothetical protein 0.0125 0.0345 0.0791
Echinococcus multilocularis COUP TF:Svp nuclear hormone receptor 0.003 0.0056 0.0056
Brugia malayi nuclear hormone receptor family member odr-7 0.0014 0.0007 0.0034
Trichomonas vaginalis ap endonuclease, putative 0.0019 0.0023 0.0127
Mycobacterium tuberculosis PROBABLE FATTY-ACID-CoA LIGASE FADD18 (FRAGMENT) (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) 0.0025 0.0038 0.013
Trypanosoma cruzi ubiquitin carboxyl-terminal hydrolase, putative 0.0039 0.0082 0.039
Loa Loa (eye worm) hypothetical protein 0.0082 0.0214 0.1042
Echinococcus granulosus Ataxin 2 N terminaldomain containing protein 0.0023 0.0033 0.0077
Echinococcus multilocularis histone lysine N methyltransferase SETMAR 0.0032 0.0062 0.0062
Brugia malayi Amyloid A4 extracellular domain containing protein 0.0324 0.0954 0.4649
Echinococcus granulosus protein kinase shaggy 0.0051 0.0119 0.0273
Echinococcus multilocularis bloom syndrome protein 0.0021 0.0026 0.0026
Leishmania major mitochondrial DNA polymerase beta-PAK, putative 0.0147 0.0413 0.2003
Schistosoma mansoni hypothetical protein 0.0082 0.0214 0.049
Trypanosoma brucei DNA polymerase kappa, putative 0.0163 0.0461 0.2241
Trypanosoma brucei AMP-activated protein kinase, gamma regulatory subunit 0.0021 0.0026 0.0119
Brugia malayi serine/threonine-protein kinase 6 0.0169 0.0479 0.2335
Echinococcus granulosus AMP activated protein kinase gamma regulatory 0.0021 0.0026 0.006
Onchocerca volvulus 0.0014 0.0007 0.0048
Loa Loa (eye worm) hypothetical protein 0.003 0.0056 0.0272
Echinococcus multilocularis histone lysine methyltransferase setb histone lysine methyltransferase eggless 0.0032 0.0062 0.0062
Mycobacterium ulcerans bifunctional enzyme MbtA: salicyl-AMP ligase (SAL-AMP ligase) + salicyl-S-ACP synthetase 0.0028 0.005 0.0085
Trypanosoma brucei DNA polymerase kappa, putative 0.0163 0.0461 0.2241
Echinococcus multilocularis GTP binding nuclear protein Ran 0.0022 0.0031 0.0031
Entamoeba histolytica casein kinase II regulatory subunit family protein 0.0038 0.0079 0.0463
Echinococcus multilocularis diuretic hormone 44 receptor GPRdih2 0.0082 0.0214 0.0214
Brugia malayi intracellular kinase 0.0051 0.0119 0.058
Echinococcus granulosus Peptidase C19 ubiquitin carboxyl terminal hydrolase 2 0.0039 0.0082 0.0187
Onchocerca volvulus Steroid hormone receptor family member cnr14 homolog 0.003 0.0056 0.0383
Trypanosoma cruzi DNA polymerase kappa, putative 0.0163 0.0461 0.2241
Plasmodium falciparum ATP-dependent 6-phosphofructokinase 0.003 0.0056 0.0101
Trypanosoma cruzi DNA polymerase beta thumb, putative 0.0044 0.0097 0.0463
Trypanosoma cruzi cdc2-related kinase 3 0.0049 0.0114 0.0549
Brugia malayi nuclear receptor NHR-67 0.0014 0.0007 0.0034
Schistosoma mansoni serine/threonine protein kinase 0.0169 0.0479 0.1099
Trichomonas vaginalis casein kinase II beta chain, putative 0.0038 0.0079 0.0463
Plasmodium falciparum DNA repair protein REV1, putative 0.0034 0.0067 0.012
Trichomonas vaginalis conserved hypothetical protein 0.0031 0.0057 0.0331
Mycobacterium ulcerans peptide synthetase Nrp (peptide synthase) 0.0028 0.005 0.0085
Giardia lamblia Kinase, CAMK CAMKL 0.0048 0.0111 0.0636
Brugia malayi latrophilin 2 splice variant baaae 0.0177 0.0505 0.2459
Trypanosoma cruzi acetyl-CoA synthetase, putative 0.0028 0.005 0.0238
Toxoplasma gondii BRCA1 C Terminus (BRCT) domain-containing protein 0.0047 0.0108 0.0195
Loa Loa (eye worm) hypothetical protein 0.0018 0.0019 0.0094
Trichomonas vaginalis casein kinase II beta chain, putative 0.0038 0.0079 0.0463
Schistosoma mansoni hypothetical protein 0.0082 0.0214 0.049
Brugia malayi CBS domain containing protein 0.0021 0.0026 0.0127
Loa Loa (eye worm) hypothetical protein 0.0018 0.0019 0.0094
Mycobacterium ulcerans long-chain-fatty-acid--CoA ligase 0.0028 0.005 0.0085
Toxoplasma gondii NEK kinase 0.0022 0.0029 0.0051
Brugia malayi RNA, U transporter 1 0.0086 0.0226 0.1101
Plasmodium vivax acyl-CoA synthetase, putative 0.0073 0.0185 0.0338
Loa Loa (eye worm) hypothetical protein 0.0259 0.0756 0.368
Echinococcus granulosus carboxylesterase 5A 0.034 0.1004 0.2302
Mycobacterium tuberculosis Probable dehydrogenase 0.0089 0.0234 0.0869
Trypanosoma brucei dihydrolipoamide dehydrogenase 0.0013 0.0004 0.0014
Schistosoma mansoni ets-related 0.0216 0.0624 0.143
Trichomonas vaginalis casein kinase II beta chain, putative 0.0038 0.0079 0.0463
Loa Loa (eye worm) nuclear receptor nhr-7B 0.0014 0.0007 0.0034
Giardia lamblia Kinase, CMGC CDK 0.0049 0.0114 0.0656
Entamoeba histolytica protein kinase, putative 0.0051 0.0119 0.07
Mycobacterium ulcerans DNA polymerase IV 0.0163 0.0461 0.0843
Loa Loa (eye worm) hypothetical protein 0.0031 0.0057 0.0279
Plasmodium vivax casein kinase II beta chain, putative 0.0038 0.0079 0.0143
Brugia malayi Patched family protein 0.0018 0.0019 0.0094
Leishmania major hypothetical protein, conserved 0.0111 0.0302 0.1465
Leishmania major serine/threonine protein kinase, putative,protein kinase, putative 0.0048 0.0111 0.0533
Entamoeba histolytica serine/threonine protein kinase, putative 0.0048 0.0111 0.0652
Echinococcus granulosus alkaline phosphatase intestinal gene 2 0.0169 0.0479 0.1098
Schistosoma mansoni protein kinase subunit beta 0.0111 0.0302 0.0692
Trypanosoma brucei cdc2-related kinase 3 0.0049 0.0114 0.0549
Mycobacterium tuberculosis Probable conserved transmembrane protein 0.0021 0.0026 0.0083
Schistosoma mansoni alzheimer's disease beta-amyloid related 0.0118 0.0325 0.0744
Trypanosoma brucei ubiquitin carboxyl-terminal hydrolase, putative 0.0039 0.0082 0.039
Brugia malayi Immunoglobulin I-set domain containing protein 0.0022 0.0032 0.0155
Brugia malayi Carboxylesterase family protein 0.0057 0.0139 0.0678
Onchocerca volvulus 0.0028 0.005 0.0345
Schistosoma mansoni nuclear hormone receptor 0.0014 0.0007 0.0016
Brugia malayi protein unc-22 0.0016 0.0013 0.0064
Brugia malayi AMP-binding enzyme family protein 0.0097 0.026 0.1267
Loa Loa (eye worm) hypothetical protein 0.0014 0.0007 0.0034
Entamoeba histolytica serine/threonine protein kinase 6, putative 0.0169 0.0479 0.2849
Toxoplasma gondii 5'-AMP-activated protein kinase subunit beta-1 family protein, putative 0.0065 0.0163 0.0298
Loa Loa (eye worm) nuclear hormone receptor family member nhr-49 0.003 0.0056 0.0272
Mycobacterium tuberculosis 3-dehydroquinate synthase AroB 0.0114 0.0313 0.1166
Echinococcus granulosus Nuclear hormone receptor HR96 0.0014 0.0007 0.0016
Echinococcus multilocularis acetylcholinesterase 0.034 0.1004 0.1004
Trichomonas vaginalis conserved hypothetical protein 0.0031 0.0057 0.0331
Schistosoma mansoni ran 0.0022 0.0031 0.0072
Loa Loa (eye worm) hypothetical protein 0.0129 0.0359 0.1748
Toxoplasma gondii Amylo-alpha-1,6-glucosidase 0.0014 0.0006 0.0008
Echinococcus granulosus SNF4:AMP activated protein kinase gamma subunit 0.0021 0.0026 0.006
Toxoplasma gondii poly(ADP-ribose) polymerase catalytic domain-containing protein 0.0031 0.0057 0.0102
Brugia malayi GTP-binding regulatory protein Gs alpha-S chain, putative 0.0047 0.0107 0.0521
Loa Loa (eye worm) hypothetical protein 0.0022 0.0032 0.0155
Loa Loa (eye worm) hypothetical protein 0.0137 0.0383 0.1865
Brugia malayi Patched family protein 0.0018 0.0019 0.0094
Loa Loa (eye worm) hypothetical protein 0.0058 0.0141 0.0689
Schistosoma mansoni tar DNA-binding protein 0.0136 0.038 0.0872
Loa Loa (eye worm) histone methyltransferase 0.0019 0.0022 0.0107
Mycobacterium ulcerans acyl-CoA synthetase 0.0028 0.005 0.0085
Trypanosoma brucei acetyl-CoA synthetase, putative 0.0028 0.005 0.0238
Echinococcus multilocularis FTZ F1 nuclear receptor protein 0.003 0.0056 0.0056
Mycobacterium tuberculosis P-hydroxybenzoyl-AMP ligase FadD22 0.0028 0.005 0.0175
Giardia lamblia 5-AMP-activated protein kinase, gamma-1 subunit 0.0228 0.0661 0.3922
Entamoeba histolytica hypothetical protein 0.0042 0.0092 0.0539
Loa Loa (eye worm) nuclear Hormone Receptor family member 0.003 0.0056 0.0272
Leishmania major acetyl-CoA synthetase, putative 0.0028 0.005 0.0238
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0286 0.0839 0.4994
Trypanosoma cruzi 5'-AMP-activated protein kinase catalytic subunit alpha, putative 0.0048 0.0111 0.0533
Brugia malayi Nuclear hormone receptor family member nhr-25 0.003 0.0056 0.0272
Loa Loa (eye worm) GTP-binding nuclear protein RAN/TC4 0.0022 0.0031 0.0152
Trichomonas vaginalis CAMK family protein kinase 0.0048 0.0111 0.0652
Echinococcus granulosus hepatocyte nuclear factor 4 alpha 0.003 0.0056 0.0128
Brugia malayi Thioredoxin reductase 0.0039 0.0082 0.04
Loa Loa (eye worm) 6-phosphofructokinase 0.0113 0.0308 0.15
Schistosoma mansoni nephrin 0.0048 0.011 0.0251
Mycobacterium tuberculosis Putative ferredoxin reductase 0.0089 0.0234 0.0869
Loa Loa (eye worm) hypothetical protein 0.0057 0.0139 0.0678
Brugia malayi hypothetical protein 0.0016 0.0012 0.0059
Toxoplasma gondii Acetyl-coenzyme A synthetase 2, putative 0.0028 0.005 0.009
Plasmodium falciparum U4/U6.U5 tri-snRNP-associated protein 2, putative 0.0016 0.0011 0.0018
Trichomonas vaginalis phosphofructokinase, putative 0.0113 0.0308 0.1827
Echinococcus granulosus Niemann Pick C1 protein 0.0302 0.0887 0.2033
Loa Loa (eye worm) nuclear hormone receptor-like 1 0.0016 0.0012 0.0059
Mycobacterium tuberculosis Bifunctional enzyme MbtA: salicyl-AMP ligase (SAL-AMP ligase) + salicyl-S-ArCP synthetase 0.0028 0.005 0.0175
Trichomonas vaginalis flap endonuclease-1, putative 0.0054 0.0129 0.0757
Chlamydia trachomatis DNA ligase 0.0031 0.0057 0.0097
Trichomonas vaginalis set domain proteins, putative 0.0247 0.0718 0.4274
Onchocerca volvulus 0.0057 0.0139 0.0952
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0047 0.0107 0.0245
Schistosoma mansoni Tr4/Tr2 (homologue) 0.003 0.0056 0.0128
Brugia malayi Immunoglobulin I-set domain containing protein 0.0022 0.0032 0.0155
Schistosoma mansoni gabp alpha 0.0071 0.0181 0.0415
Entamoeba histolytica ubiquitin carboxyl-terminal hydrolase domain containing protein 0.0016 0.0011 0.0057
Trypanosoma cruzi Serine/threonine-protein kinase NEK11, putative 0.0022 0.0029 0.0135
Trypanosoma cruzi inosine-5'-monophosphate dehydrogenase, putative 0.0021 0.0026 0.0119
Trypanosoma cruzi dihydrolipoyl dehydrogenase, putative 0.0013 0.0004 0.0014
Brugia malayi tailless protein 0.0014 0.0007 0.0034
Loa Loa (eye worm) 5'-AMP-activated protein kinase 0.0111 0.0302 0.1472
Leishmania major histone deacetylase, putative 0.0561 0.1678 0.8175
Echinococcus granulosus Jumonji AT rich interactive domain 1B 0.002 0.0023 0.0053
Loa Loa (eye worm) O-glycosyl hydrolase family 30 protein 0.0254 0.0739 0.3602
Echinococcus multilocularis Niemann Pick C1 protein 0.0431 0.1283 0.1283
Echinococcus granulosus 5' AMP activated protein kinase catalytic 0.0236 0.0685 0.1571
Mycobacterium ulcerans acyl-CoA synthetase 0.0028 0.005 0.0085
Echinococcus granulosus ecdysone induced protein 78C 0.003 0.0056 0.0128
Onchocerca volvulus 0.0051 0.0119 0.0814
Loa Loa (eye worm) CAMK/MLCK protein kinase 0.0016 0.0013 0.0064
Trichomonas vaginalis glucosylceramidase, putative 0.0254 0.0739 0.44
Loa Loa (eye worm) hypothetical protein 0.0018 0.0019 0.0094
Loa Loa (eye worm) hypothetical protein 0.0086 0.0226 0.11
Mycobacterium ulcerans cystathionine beta-synthase 0.0021 0.0026 0.004
Onchocerca volvulus Casein kinase II subunit beta homolog 0.0038 0.0079 0.0542
Brugia malayi Immunoglobulin I-set domain containing protein 0.0036 0.0073 0.0355
Echinococcus multilocularis cyclin dependent kinase 1 0.0049 0.0114 0.0114
Brugia malayi protein C24B5.3 0.0018 0.0019 0.0094
Entamoeba histolytica hypothetical protein 0.0042 0.0092 0.0539
Echinococcus granulosus histone lysine methyltransferase setb 0.0032 0.0062 0.0142
Plasmodium falciparum ataxin-2 like protein, putative 0.0051 0.012 0.0218
Mycobacterium tuberculosis Fatty-acid-AMP ligase FadD30 (fatty-acid-AMP synthetase) (fatty-acid-AMP synthase) 0.0073 0.0185 0.0683
Brugia malayi hypothetical protein 0.0434 0.129 0.6286
Brugia malayi jmjC domain containing protein 0.0016 0.0013 0.0063
Chlamydia trachomatis UDP-N-acetylglucosamine 1-carboxyvinyltransferase 0.018 0.0513 0.0937
Entamoeba histolytica serine/threonine protein kinase, putative 0.0022 0.0029 0.0165
Plasmodium falciparum NIMA related kinase 4 0.0022 0.0029 0.0051
Loa Loa (eye worm) hypothetical protein 0.0021 0.0026 0.0127
Schistosoma mansoni DNA helicase recq1 0.0021 0.0026 0.006
Plasmodium falciparum dihydrolipoyl dehydrogenase, apicoplast 0.0013 0.0004 0.0005
Loa Loa (eye worm) hypothetical protein 0.003 0.0056 0.0272
Schistosoma mansoni dihydrolipoamide dehydrogenase 0.0013 0.0004 0.001
Trypanosoma cruzi acetyl-CoA synthetase, putative 0.0028 0.005 0.0238
Plasmodium falciparum JmjC domain-containing protein, putative 0.0016 0.0013 0.0021
Onchocerca volvulus 0.0018 0.0019 0.0131
Brugia malayi Nuclear hormone receptor family member nhr-14 0.003 0.0056 0.0272
Leishmania major cell division protein kinase 2,cdc2-related kinase 0.0049 0.0114 0.0549
Schistosoma mansoni family S9 non-peptidase homologue (S09 family) 0.0057 0.0139 0.0319
Onchocerca volvulus 0.0018 0.0019 0.0131
Giardia lamblia Kinase, CAMK CAMKL 0.0048 0.0111 0.0636
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0016 0.0011 0.0057
Schistosoma mansoni cell adhesion molecule 0.0046 0.0105 0.024
Schistosoma mansoni hypothetical protein 0.0125 0.0345 0.0791
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0016 0.0011 0.0057
Echinococcus multilocularis Jumonji, AT rich interactive domain 1B 0.002 0.0023 0.0023
Schistosoma mansoni phosphatidylserine receptor 0.0016 0.0013 0.003
Onchocerca volvulus 0.0434 0.129 0.8829
Brugia malayi Bloom's syndrome protein homolog 0.0021 0.0026 0.0127
Toxoplasma gondii chloride transporter, chloride channel (ClC) family protein 0.0021 0.0026 0.0045
Mycobacterium leprae probable 3-phosphoshikimate 1-carboxyvinyl transferase AroA (5-ENOLPYRUVYLSHIKIMATE-3-PHOSPHATE SYNTHASE) (EPSP SYNTHASE) (EPSPS 0.0294 0.0863 0.318
Trypanosoma brucei DNA polymerase beta thumb, putative 0.0044 0.0097 0.0463
Trichomonas vaginalis glucosylceramidase, putative 0.0254 0.0739 0.44
Loa Loa (eye worm) hypothetical protein 0.0068 0.0173 0.0841
Brugia malayi nuclear hormone receptor 0.003 0.0056 0.0272
Plasmodium vivax acetyl-CoA synthetase, putative 0.0028 0.005 0.009
Leishmania major glycogen synthase kinase, putative;with=GeneDB:LinJ18_V3.0270 0.0051 0.0119 0.0572
Echinococcus granulosus neuroglian 0.0048 0.011 0.0251
Trichomonas vaginalis histone deacetylase 1, 2 ,3, putative 0.0561 0.1678 1
Loa Loa (eye worm) pigment dispersing factor receptor c 0.0259 0.0756 0.368
Loa Loa (eye worm) hypothetical protein 0.0159 0.0449 0.2186
Onchocerca volvulus Casein kinase II subunit beta homolog 0.0038 0.0079 0.0542
Mycobacterium tuberculosis Probable peptide synthetase Nrp (peptide synthase) 0.0028 0.005 0.0175
Toxoplasma gondii phosphofructokinase PFKII 0.003 0.0056 0.0101
Trichomonas vaginalis casein kinase II beta chain, putative 0.0038 0.0079 0.0463
Loa Loa (eye worm) hypothetical protein 0.0073 0.0185 0.0902
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD8 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0028 0.005 0.0175
Echinococcus multilocularis hemicentin 1 0.0022 0.0032 0.0032
Loa Loa (eye worm) hypothetical protein 0.0031 0.0057 0.0279
Toxoplasma gondii hypothetical protein 0.0018 0.0019 0.0032
Brugia malayi hypothetical protein 0.0018 0.0019 0.0094
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.003 0.0056 0.0056
Leishmania major DNA damage repair protein, putative 0.0034 0.0067 0.0318
Toxoplasma gondii histone lysine demethylase JMJD6a 0.0016 0.0013 0.0021
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0013 0.0004 0.0012
Mycobacterium tuberculosis Probable nitrite reductase [NAD(P)H] large subunit [FAD flavoprotein] NirB 0.0089 0.0234 0.0869
Brugia malayi CLC chloride channel protein 0.0021 0.0026 0.0127
Trichomonas vaginalis histone deacetylase, putative 0.0561 0.1678 1
Echinococcus granulosus Transcription factor JmjC domain containing protein 0.0061 0.015 0.0343
Brugia malayi CXXC zinc finger family protein 0.0058 0.0142 0.0689
Toxoplasma gondii CBS family protein 0.0021 0.0026 0.0045
Mycobacterium leprae DIHYDROLIPOAMIDE DEHYDROGENASE LPD (LIPOAMIDE REDUCTASE (NADH)) (LIPOYL DEHYDROGENASE) (DIHYDROLIPOYL DEHYDROGENASE) (DIAPHORASE 0.0099 0.0265 0.0907
Loa Loa (eye worm) hypothetical protein 0.0021 0.0026 0.0127
Echinococcus multilocularis u4:u6.u5 tri snrnp associated protein 2 0.0016 0.0011 0.0011
Trypanosoma brucei DNA polymerase kappa, putative 0.0088 0.0231 0.1118
Trypanosoma cruzi histone deacetylase 1, putative 0.0561 0.1678 0.8175
Brugia malayi MH2 domain containing protein 0.0124 0.0342 0.1665
Loa Loa (eye worm) hypothetical protein 0.003 0.0056 0.0271
Loa Loa (eye worm) CXXC zinc finger family protein 0.0058 0.0142 0.0689
Loa Loa (eye worm) hypothetical protein 0.0434 0.129 0.6286
Plasmodium falciparum ATP-dependent 6-phosphofructokinase 0.003 0.0056 0.0101
Schistosoma mansoni RAR-like nuclear receptor 0.003 0.0056 0.0128
Schistosoma mansoni cpg binding protein 0.0058 0.0142 0.0324
Toxoplasma gondii propionate-CoA ligase 0.0028 0.005 0.009
Leishmania major CBS domain protein, conserved 0.0021 0.0026 0.0119
Loa Loa (eye worm) hypothetical protein 0.0073 0.0185 0.0902
Entamoeba histolytica casein kinase II regulatory subunit family protein 0.0038 0.0079 0.0463
Echinococcus multilocularis tar DNA binding protein 0.0136 0.038 0.038
Mycobacterium ulcerans 3-dehydroquinate synthase 0.0114 0.0313 0.057
Echinococcus granulosus nuclear receptor 2DBD gamma 0.003 0.0056 0.0128
Trypanosoma cruzi CMGC/DYRK protein kinase, putative 0.0189 0.0542 0.2636
Loa Loa (eye worm) hypothetical protein 0.0036 0.0073 0.0355
Trypanosoma cruzi aurora B kinase, putative 0.0169 0.0479 0.2329
Schistosoma mansoni hypothetical protein 0.0086 0.0226 0.0518
Loa Loa (eye worm) CMGC/CDK/CDC2 protein kinase 0.0049 0.0114 0.0556
Brugia malayi hypothetical protein 0.0051 0.012 0.0583
Brugia malayi Nuclear hormone receptor E75 0.0014 0.0007 0.0034
Echinococcus granulosus tumor protein p63 0.0354 0.1046 0.2397
Mycobacterium ulcerans O-succinylbenzoic acid--CoA ligase 0.0028 0.005 0.0085
Plasmodium vivax ubiquitin carboxyl-terminal hydrolase 13, putative 0.0016 0.0011 0.0018
Brugia malayi dihydrolipoyl dehydrogenase, mitochondrial precursor, putative 0.0013 0.0004 0.0022
Trypanosoma brucei ATP-dependent DEAD/H DNA helicase recQ, putative 0.0021 0.0026 0.0119
Brugia malayi Immunoglobulin I-set domain containing protein 0.0022 0.0032 0.0155
Trichomonas vaginalis glucosylceramidase, putative 0.0254 0.0739 0.44
Echinococcus granulosus FTZ F1 nuclear receptor protein 0.003 0.0056 0.0128
Mycobacterium tuberculosis Conserved hypothetical protein 0.0109 0.0297 0.1106
Echinococcus multilocularis ubiquitin carboxyl terminal hydrolase 5 0.0016 0.0011 0.0011
Schistosoma mansoni histone deacetylase 1 2 3 0.0283 0.0829 0.1899
Brugia malayi hypothetical protein 0.0018 0.0019 0.0094
Brugia malayi AMP-binding enzyme family protein 0.0097 0.026 0.1267
Mycobacterium tuberculosis Fatty-acid-CoA synthetase FadD17 (fatty-acid-CoA synthase) (fatty-acid-CoA ligase) 0.0028 0.005 0.0175
Mycobacterium ulcerans fatty-acid-CoA ligase 0.0073 0.0185 0.0333
Brugia malayi ecdysteroid receptor 0.003 0.0056 0.0272
Trypanosoma brucei DNA polymerase kappa, putative 0.0088 0.0231 0.1118
Schistosoma mansoni titin 0.0016 0.0013 0.003
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0032 0.0062 0.0142
Loa Loa (eye worm) hypothetical protein 0.0018 0.0019 0.0094
Loa Loa (eye worm) CMGC/GSK protein kinase 0.0051 0.0119 0.058
Loa Loa (eye worm) hypothetical protein 0.0018 0.0019 0.0094
Brugia malayi jmjC domain containing protein 0.0064 0.016 0.0779
Brugia malayi Patched related family protein 10 0.0018 0.0019 0.0094
Trichomonas vaginalis histone deacetylase, putative 0.0561 0.1678 1
Schistosoma mansoni family S9 non-peptidase homologue (S09 family) 0.0057 0.0139 0.0319
Onchocerca volvulus Protein ultraspiracle homolog 0.003 0.0056 0.0383
Echinococcus multilocularis terminal deoxycytidyl transferase rev1 0.0109 0.0297 0.0297
Loa Loa (eye worm) hypothetical protein 0.0561 0.1678 0.8176
Trypanosoma brucei dihydrolipoyl dehydrogenase 0.0013 0.0004 0.0014
Schistosoma mansoni patched 1 0.013 0.036 0.0824
Trypanosoma cruzi histone deacetylase, putative 0.0683 0.2053 1
Plasmodium falciparum importin beta, putative 0.003 0.0056 0.0099
Mycobacterium ulcerans fatty-acid-CoA ligase 0.0097 0.026 0.0472
Loa Loa (eye worm) DR-78 0.0014 0.0007 0.0034
Trichomonas vaginalis conserved hypothetical protein 0.0013 0.0004 0.0012
Mycobacterium ulcerans non-ribosomal peptide synthetase MbtF 0.0028 0.005 0.0085
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0013 0.0004 0.0012
Trypanosoma brucei ubiquitin carboxyl-terminal hydrolase, putative 0.0016 0.0011 0.0047
Mycobacterium tuberculosis Probable chorismate synthase AroF (5-enolpyruvylshikimate-3-phosphate phospholyase) 0.0881 0.2658 1
Brugia malayi Ubiquitin carboxyl-terminal hydrolase family protein 0.0016 0.0011 0.0055
Schistosoma mansoni protein kinase subunit gamma 0.0228 0.0661 0.1515
Trypanosoma cruzi BRCA1 C Terminus (BRCT) domain containing protein, putative 0.0031 0.0057 0.0271
Loa Loa (eye worm) acetyltransferase 0.015 0.0423 0.206
Onchocerca volvulus Rap guanine nucleotide exchange factor 1 homolog 0.0185 0.0531 0.3631
Leishmania major chloride channel protein, putative 0.0021 0.0026 0.0119
Echinococcus granulosus BC026374 protein S09 family 0.0057 0.0139 0.0319
Loa Loa (eye worm) hypothetical protein 0.0185 0.0529 0.2578
Loa Loa (eye worm) hypothetical protein 0.0018 0.0019 0.0094
Echinococcus multilocularis cyclin dependent kinase 1 0.0049 0.0114 0.0114
Trichomonas vaginalis ran, putative 0.0022 0.0031 0.0176
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0286 0.0839 0.4994
Echinococcus granulosus snurportin 1 0.0322 0.095 0.2176
Echinococcus multilocularis acetyl coenzyme A synthetase, cytoplasmic 0.0028 0.005 0.005
Mycobacterium tuberculosis Probable exodeoxyribonuclease III protein XthA (exonuclease III) (EXO III) (AP endonuclease VI) 0.0019 0.0023 0.0071
Brugia malayi Steroid receptor seven-up type 2 0.003 0.0056 0.0272
Trypanosoma cruzi ATP-dependent 6-phosphofructokinase, glycosomal 0.0113 0.0308 0.1493
Echinococcus granulosus Nuclear hormone receptor HR96 0.0014 0.0007 0.0016
Schistosoma mansoni chromosome transmission fidelity factor 0.0031 0.0057 0.0131
Entamoeba histolytica protein kinase domain containing protein 0.0051 0.0119 0.07
Brugia malayi hypothetical protein 0.0036 0.0073 0.0355
Trichomonas vaginalis conserved hypothetical protein 0.0031 0.0057 0.0331
Loa Loa (eye worm) hypothetical protein 0.0021 0.0026 0.0127
Leishmania major flap endonuclease-1 (FEN-1), putative 0.0054 0.0129 0.0619
Schistosoma mansoni histone deacetylase 4 5 0.0683 0.2053 0.4706
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0039 0.0082 0.0478
Schistosoma mansoni DNA polymerase IV / kappa 0.0034 0.0067 0.0153
Trichomonas vaginalis carboxylesterase domain containing protein, putative 0.0057 0.0139 0.082
Loa Loa (eye worm) hypothetical protein 0.0185 0.0529 0.2578
Mycobacterium tuberculosis Phenyloxazoline synthase MbtB (phenyloxazoline synthetase) 0.0028 0.005 0.0175
Onchocerca volvulus Basement membrane proteoglycan homolog 0.0022 0.0032 0.0218
Toxoplasma gondii patched family protein 0.0018 0.0019 0.0032
Mycobacterium ulcerans acyl-CoA synthetase 0.0097 0.026 0.0472
Loa Loa (eye worm) exodeoxyribonuclease III family protein 0.0019 0.0023 0.0111
Echinococcus granulosus receptor type tyrosine protein phosphatase 0.0022 0.0032 0.0073
Toxoplasma gondii histone lysine demethylase JMJC1/KDM5D/JARID1D 0.0016 0.0013 0.0021
Trichomonas vaginalis CMGC family protein kinase 0.0049 0.0114 0.0672
Trichomonas vaginalis DNA helicase recq, putative 0.0021 0.0026 0.0146
Echinococcus granulosus acetylcholinesterase 0.034 0.1004 0.2302
Echinococcus multilocularis dna polymerase eta 0.0136 0.0378 0.0378
Schistosoma mansoni DNA ligase IV 0.0031 0.0057 0.0131
Loa Loa (eye worm) hypothetical protein 0.0057 0.0139 0.0678
Schistosoma mansoni hypothetical protein 0.0125 0.0345 0.0791
Loa Loa (eye worm) jmjC domain-containing protein 0.0016 0.0013 0.0063
Trichomonas vaginalis CAMK family protein kinase 0.0048 0.0111 0.0652
Schistosoma mansoni protein phosphatase 2C 0.0016 0.0013 0.003
Trichomonas vaginalis CAMK family protein kinase 0.0048 0.0111 0.0652
Loa Loa (eye worm) histone deacetylase 3 0.0561 0.1678 0.8176
Echinococcus multilocularis replication factor c subunit 1 0.0031 0.0057 0.0057
Trichomonas vaginalis conserved hypothetical protein 0.0013 0.0004 0.0012
Brugia malayi hypothetical protein 0.0033 0.0064 0.0313
Entamoeba histolytica histone deacetylase, putative 0.0561 0.1678 1
Trypanosoma brucei unspecified product 0.0075 0.0194 0.0936
Loa Loa (eye worm) hypothetical protein 0.0052 0.0122 0.0593
Plasmodium falciparum histone deacetylase 1 0.0561 0.1678 0.309
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0286 0.0839 0.4994
Onchocerca volvulus 0.0473 0.1411 0.9651
Trichomonas vaginalis glutathione reductase, putative 0.0013 0.0004 0.0017
Schistosoma mansoni chloride channel protein 0.0021 0.0026 0.006
Brugia malayi calcium-independent alpha-latrotoxin receptor 2, putative 0.0082 0.0214 0.1042
Brugia malayi BRCA1-associated protein 2 containing protein 0.0013 0.0002 0.0008
Brugia malayi Histone deacetylase family protein 0.0683 0.2053 1
Brugia malayi Immunoglobulin I-set domain containing protein 0.0022 0.0032 0.0155
Trichomonas vaginalis casein kinase II beta chain, putative 0.0038 0.0079 0.0463
Brugia malayi Patched related family protein 12 0.0018 0.0019 0.0094
Echinococcus granulosus histone deacetylase 1 0.0561 0.1678 0.3847
Brugia malayi DKFZp564C0469 protein 0.0031 0.0057 0.0279
Loa Loa (eye worm) hypothetical protein 0.0018 0.0019 0.0094
Treponema pallidum fructose-bisphosphate aldolase 0.0286 0.0839 1
Brugia malayi topoisomerase 0.0031 0.0057 0.0279
Brugia malayi histone deacetylase 3 (HD3) 0.0561 0.1678 0.8176
Trichomonas vaginalis CAMK family protein kinase 0.0048 0.0111 0.0652
Trypanosoma cruzi apurinic/apyrimidinic endonuclease 0.0019 0.0023 0.0103
Loa Loa (eye worm) hypothetical protein 0.0022 0.0032 0.0155
Brugia malayi nuclear receptor subfamily 1, group D, member 1, putative 0.0014 0.0007 0.0034
Echinococcus multilocularis neuroligin 0.0057 0.0139 0.0139
Schistosoma mansoni tar DNA-binding protein 0.0136 0.038 0.0872
Trypanosoma cruzi dihydrolipoyl dehydrogenase, putative 0.0013 0.0004 0.0014
Toxoplasma gondii ubiquitin specific protease 39 isoform 2, putative 0.0016 0.0011 0.0018
Loa Loa (eye worm) hypothetical protein 0.0057 0.0139 0.0678
Toxoplasma gondii IQ calmodulin-binding motif domain-containing protein 0.0014 0.0006 0.0008
Loa Loa (eye worm) hypothetical protein 0.0302 0.0887 0.432
Loa Loa (eye worm) chloride channel 3 0.0021 0.0026 0.0127
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0014 0.0007 0.0007
Echinococcus granulosus lysine specific demethylase 5A 0.0064 0.016 0.0366
Brugia malayi Carboxylesterase family protein 0.0057 0.0139 0.0678
Trichomonas vaginalis glucosylceramidase, putative 0.0254 0.0739 0.44
Loa Loa (eye worm) 6-phosphofructokinase 0.0113 0.0308 0.15
Toxoplasma gondii serine/threonine specific protein phosphatase 0.0014 0.0006 0.0008
Loa Loa (eye worm) hypothetical protein 0.0022 0.0032 0.0155
Brugia malayi ancient conserved domain protein 4 0.0021 0.0026 0.0127
Giardia lamblia Endonuclease/Exonuclease/phosphatase 0.0019 0.0023 0.011
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0047 0.0107 0.0245
Loa Loa (eye worm) hypothetical protein 0.0031 0.0057 0.0279
Toxoplasma gondii UBA/TS-N domain-containing protein 0.0016 0.0011 0.0018
Loa Loa (eye worm) hypothetical protein 0.0028 0.005 0.0245
Echinococcus granulosus casein kinase ii subunit beta 0.0038 0.0079 0.0182
Trichomonas vaginalis RNA polymerase II ctd phosphatase, putative 0.0031 0.0057 0.0331
Trypanosoma cruzi GTP-binding nuclear protein rtb2, putative 0.0022 0.0031 0.0144
Loa Loa (eye worm) nuclear receptor NHR-67 0.0014 0.0007 0.0034
Echinococcus granulosus titin 0.0016 0.0013 0.003
Schistosoma mansoni serine/threonine protein kinase 0.0048 0.0111 0.0254
Schistosoma mansoni ecdysone-induced protein 78c (dr-78) 0.0016 0.0012 0.0028
Echinococcus multilocularis Immunoglobulin 0.0036 0.0073 0.0073
Schistosoma mansoni importin beta-1 0.003 0.0056 0.0127
Trichomonas vaginalis CMGC family protein kinase 0.0051 0.0119 0.07
Brugia malayi Nuclear hormone receptor family member nhr-31 0.003 0.0056 0.0272
Schistosoma mansoni ubiquitin-specific peptidase 5 (C19 family) 0.0016 0.0011 0.0026
Loa Loa (eye worm) hypothetical protein 0.0046 0.0105 0.051
Toxoplasma gondii NEK kinase 0.0022 0.0029 0.0051
Loa Loa (eye worm) IMP dehydrogenase 1 0.0021 0.0026 0.0127
Loa Loa (eye worm) CMGC/DYRK/DYRK1 protein kinase 0.0189 0.0542 0.2642
Echinococcus granulosus histone lysine N methyltransferase MLL3 0.0019 0.0022 0.005
Leishmania major ATP-dependent DEAD/H DNA helicase recQ, putative 0.0021 0.0026 0.0119
Loa Loa (eye worm) hypothetical protein 0.0018 0.0019 0.0094
Plasmodium falciparum AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.0019 0.0023 0.0039
Trichomonas vaginalis importin beta-1, putative 0.0024 0.0038 0.0218
Trichomonas vaginalis glucosylceramidase, putative 0.0175 0.05 0.2972
Brugia malayi RNA recognition motif domain containing protein 0.0136 0.038 0.1852
Trichomonas vaginalis phosphofructokinase, putative 0.003 0.0056 0.0326
Trypanosoma brucei BRCA1 C Terminus (BRCT) domain containing protein, putative 0.0031 0.0057 0.0271
Schistosoma mansoni protein kinase 0.0169 0.0479 0.1099
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD35 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0069 0.0173 0.0637
Mycobacterium ulcerans inosine 5-monophosphate dehydrogenase 0.0021 0.0026 0.004
Treponema pallidum UDP-N-acetylglucosamine 1-carboxyvinyltransferase 0.018 0.0513 0.6091
Loa Loa (eye worm) ubiquitin carboxyl-terminal hydrolase 0.0016 0.0011 0.0055
Echinococcus granulosus dihydrolipoamide dehydrogenase 0.0013 0.0004 0.001
Echinococcus granulosus flap endonuclease 1 0.0054 0.0129 0.0295
Loa Loa (eye worm) hypothetical protein 0.003 0.0056 0.0272
Loa Loa (eye worm) hypothetical protein 0.0018 0.0019 0.0094
Trichomonas vaginalis STE family protein kinase 0.0022 0.0029 0.0165
Plasmodium falciparum protein kinase 5 0.0049 0.0114 0.0208
Trypanosoma cruzi long-chain-fatty-acid-CoA ligase, putative 0.0028 0.005 0.0238
Schistosoma mansoni tar DNA-binding protein 0.0136 0.038 0.0872
Trichomonas vaginalis AGC family protein kinase 0.0169 0.0479 0.2849
Echinococcus granulosus EGFP:Bcl2 fusion protein 0.0086 0.0226 0.0518
Toxoplasma gondii ATPase, AAA family protein 0.0031 0.0057 0.0102
Schistosoma mansoni serine/threonine protein kinase 0.0022 0.0029 0.0067
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0047 0.0107 0.0245
Loa Loa (eye worm) hypothetical protein 0.0255 0.0744 0.3626
Mycobacterium ulcerans acyl-CoA synthetase 0.0028 0.005 0.0085
Onchocerca volvulus Uncharacterized RING finger protein homolog 0.0013 0.0002 0.0011
Onchocerca volvulus 0.003 0.0056 0.0383
Echinococcus granulosus BRCA1 associated protein 0.0013 0.0002 0.0004
Loa Loa (eye worm) patched family protein 0.0018 0.0019 0.0094
Trypanosoma brucei unspecified product 0.015 0.0421 0.2043
Plasmodium vivax glycogen synthase kinase 3, putative 0.0051 0.0119 0.0216
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0013 0.0004 0.0014
Trichomonas vaginalis glucosylceramidase, putative 0.0166 0.0472 0.2808
Trypanosoma brucei protein kinase, putative 0.0051 0.0119 0.0572
Echinococcus granulosus neurotracting:lsamp:neurotrimin:obcam 0.0046 0.0105 0.024
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0013 0.0004 0.0012
Brugia malayi serine/threonine protein kinase 6 0.0169 0.0479 0.2335
Giardia lamblia Kinase, NEK 0.0022 0.0029 0.0149
Entamoeba histolytica long-chain-fatty-acid--CoA ligase, putative 0.0028 0.005 0.0291
Loa Loa (eye worm) AUR protein kinase 0.0169 0.0479 0.2335
Schistosoma mansoni zinc finger protein 0.0014 0.0007 0.0016
Trypanosoma cruzi ubiquitin carboxyl-terminal hydrolase, putative 0.0039 0.0082 0.039
Toxoplasma gondii NADPH-glutathione reductase 0.0013 0.0004 0.0005
Echinococcus granulosus intestinal type alkaline phosphatase 1 0.0169 0.0479 0.1098
Mycobacterium leprae PROBABLE DNA LIGASE [NAD DEPENDENT] LIGA (POLYDEOXYRIBONUCLEOTIDE SYNTHASE [NAD+]) 0.0031 0.0057 0.0118
Trichomonas vaginalis AGC family protein kinase 0.0169 0.0479 0.2849
Trichomonas vaginalis phosphofructokinase, putative 0.003 0.0056 0.0326
Echinococcus multilocularis acetylcholinesterase 0.034 0.1004 0.1004
Entamoeba histolytica pyrophosphate-dependent phosphofructokinase 0.003 0.0056 0.0326
Echinococcus multilocularis nibrin 0.0031 0.0057 0.0057
Trypanosoma cruzi SNF1-related protein kinases, putative 0.0048 0.0111 0.0533
Loa Loa (eye worm) phosphofructokinase 0.0113 0.0308 0.15
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0125 0.0345 0.0791
Echinococcus multilocularis histone deacetylase 6 0.0683 0.2053 0.2053
Toxoplasma gondii chorismate synthase, putative 0.1786 0.5428 1
Echinococcus granulosus tar DNA binding protein 0.0136 0.038 0.0872
Leishmania major chloride channel protein, putative 0.0021 0.0026 0.0119
Echinococcus granulosus nuclear receptor subfamily 1 group D 0.0016 0.0012 0.0028
Trypanosoma cruzi histone deacetylase, putative 0.0283 0.0829 0.4032
Mycobacterium ulcerans long-chain fatty-acid CoA ligase 0.0097 0.026 0.0472
Trichomonas vaginalis CAMK family protein kinase 0.0048 0.0111 0.0652
Schistosoma mansoni topbp1 0.0031 0.0057 0.0131
Schistosoma mansoni jumonji domain containing protein 0.0016 0.0013 0.003
Schistosoma mansoni serine/threonine protein kinase 0.0048 0.0111 0.0254
Trypanosoma brucei DNA polymerase kappa, putative 0.0163 0.0461 0.2241
Brugia malayi acetyl-Coenzyme A synthetase 2 0.0028 0.005 0.0245
Brugia malayi Fli-1 protein 0.0216 0.0624 0.304
Leishmania major ATP-dependent phosphofructokinase 0.0113 0.0308 0.1493
Trypanosoma brucei cdc2-related kinase 1 0.0049 0.0114 0.0549
Echinococcus granulosus lachesin 0.0022 0.0032 0.0073
Loa Loa (eye worm) hypothetical protein 0.0014 0.0007 0.0034
Brugia malayi Patched family protein 0.0018 0.0019 0.0094
Treponema pallidum diphosphate--fructose-6-phosphate 1-phosphotransferase 0.0113 0.0308 0.3636
Mycobacterium ulcerans acyl-CoA synthetase 0.0097 0.026 0.0472
Trichomonas vaginalis casein kinase II beta chain, putative 0.0038 0.0079 0.0463
Brugia malayi Patched family protein 0.0018 0.0019 0.0094
Loa Loa (eye worm) hypothetical protein 0.0283 0.0829 0.4036
Leishmania major protein kinase, putative,serine/threonine-protein kinase Nek1, putative 0.0022 0.0029 0.0135
Echinococcus multilocularis lachesin 0.0022 0.0032 0.0032
Echinococcus granulosus 5'partial|cyclin dependent kinase 1 0.0049 0.0114 0.0262
Echinococcus granulosus dnaJ subfamily B 0.083 0.2503 0.5738
Trypanosoma cruzi flap endonuclease-1 (FEN-1), putative 0.0054 0.0129 0.0619
Schistosoma mansoni nuclear receptor nhr-48 0.0014 0.0007 0.0016
Mycobacterium tuberculosis Probable medium chain fatty-acid-CoA ligase FadD14 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0028 0.005 0.0175
Brugia malayi Carboxylesterase family protein 0.0057 0.0139 0.0678
Entamoeba histolytica cell division protein kinase 2, putative 0.0049 0.0114 0.0672
Entamoeba histolytica recQ family helicase, putative 0.0021 0.0026 0.0146
Wolbachia endosymbiont of Brugia malayi hemolysin 0.0021 0.0026 0.0425
Brugia malayi Patched family protein 0.0018 0.0019 0.0094
Loa Loa (eye worm) hypothetical protein 0.0097 0.026 0.1267
Plasmodium vivax glutathione reductase, putative 0.0039 0.0082 0.0148
Echinococcus multilocularis ubiquitin carboxyl terminal hydrolase 8 0.0039 0.0082 0.0082
Schistosoma mansoni nuclear hormone receptor 0.0014 0.0007 0.0016
Plasmodium vivax ataxin-2 like protein, putative 0.0051 0.012 0.0218
Echinococcus granulosus cyclin dependent kinase 1 0.0049 0.0114 0.0262
Mycobacterium leprae Probable fatty-acid-CoA synthetase FadD22 (fatty-acid-CoA ligase) (fatty-acid-CoA synthase) 0.0028 0.005 0.0093
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0047 0.0107 0.0107
Trichomonas vaginalis conserved hypothetical protein 0.0039 0.0082 0.0478
Giardia lamblia Histone deacetylase 0.0561 0.1678 1
Trichomonas vaginalis antibiotic synthetase, putative 0.0028 0.005 0.0291
Leishmania major trypanothione reductase 0.0039 0.0082 0.0392
Leishmania major 4-coumarate:coa ligase-like protein 0.0097 0.026 0.126
Brugia malayi 5'-AMP-activated protein kinase, beta subunit, complex-interacting region containing protein 0.0111 0.0302 0.1472
Echinococcus multilocularis neuroglian 0.0022 0.0032 0.0032
Trypanosoma brucei long-chain-fatty-acid-CoA ligase, putative 0.0028 0.005 0.0238
Echinococcus multilocularis SNF4:AMP activated protein kinase gamma subunit 0.0021 0.0026 0.0026
Trichomonas vaginalis replication factor C large subunit, putative 0.0031 0.0057 0.0331
Schistosoma mansoni niemann-pick C1 (NPC1) 0.0307 0.0901 0.2065
Trypanosoma brucei Voltage-gated Chloride channel Like 1 0.0021 0.0026 0.0119
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0013 0.0004 0.0012
Schistosoma mansoni jumonji domain containing protein 0.0061 0.015 0.0343
Echinococcus granulosus thioredoxin glutathione reductase 0.0039 0.0084 0.0192
Trichomonas vaginalis CMGC family protein kinase 0.0049 0.0114 0.0672
Echinococcus multilocularis alkaline phosphatase, intestinal, gene 2 0.0169 0.0479 0.0479
Loa Loa (eye worm) hypothetical protein 0.003 0.0056 0.0272
Loa Loa (eye worm) transcription factor SMAD2 0.0124 0.0342 0.1665
Giardia lamblia Hypothetical protein 0.0016 0.0011 0.0041
Echinococcus granulosus nuclear receptor nhr 48 0.0014 0.0007 0.0016
Loa Loa (eye worm) fli-1 protein 0.0216 0.0624 0.304
Plasmodium falciparum GTP-binding nuclear protein RAN/TC4 0.0022 0.0031 0.0055
Echinococcus multilocularis lysine specific demethylase 5A 0.0061 0.015 0.015
Mycobacterium tuberculosis Probable membrane NADH dehydrogenase NdhA 0.0089 0.0234 0.0869
Mycobacterium tuberculosis NAD(P)H quinone reductase LpdA 0.0099 0.0265 0.0983
Trichomonas vaginalis Importin beta-1 subunit, putative 0.0024 0.0038 0.0218
Trypanosoma cruzi AMP-activated protein kinase, gamma regulatory subunit 0.0021 0.0026 0.0119
Trichomonas vaginalis CAMK family protein kinase 0.0022 0.0029 0.0165
Loa Loa (eye worm) TK/KIN16 protein kinase 0.0524 0.1566 0.763
Loa Loa (eye worm) Csnk2b protein 0.0038 0.0079 0.0386
Loa Loa (eye worm) hypothetical protein 0.0014 0.0007 0.0034
Schistosoma mansoni neuroglian 0.0022 0.0032 0.0073
Mycobacterium tuberculosis Probable chain -fatty-acid-CoA ligase FadD13 (fatty-acyl-CoA synthetase) 0.0097 0.026 0.0965
Mycobacterium ulcerans hypothetical protein 0.0021 0.0026 0.004
Echinococcus granulosus jumonji domain containing 1A 0.0016 0.0013 0.003
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0047 0.0107 0.0245
Schistosoma mansoni coup transcription factor 0.003 0.0056 0.0128
Trypanosoma brucei trypanothione reductase 0.0039 0.0082 0.0392
Trypanosoma cruzi DNA damage repair protein, putative 0.0034 0.0067 0.0318
Schistosoma mansoni family S9 non-peptidase homologue (S09 family) 0.034 0.1004 0.2302
Plasmodium vivax JmjC domain containing protein 0.0016 0.0013 0.0021
Schistosoma mansoni retinoid-x-receptor (RXR) 0.003 0.0056 0.0128
Echinococcus granulosus histone deacetylase 6 0.0683 0.2053 0.4706
Echinococcus multilocularis Nuclear hormone receptor HR96 0.0014 0.0007 0.0007
Mycobacterium tuberculosis POSSIBLE PARA-NITROBENZYL ESTERASE (FRAGMENT) 0.0057 0.0139 0.0509
Schistosoma mansoni ubiquitously transcribed sex (X/Y) chromosome tetratricopeptide repeat protein-related 0.0016 0.0013 0.003
Schistosoma mansoni family S9 non-peptidase homologue (S09 family) 0.0057 0.0139 0.0319
Trypanosoma brucei JmjC domain, hydroxylase, putative 0.0016 0.0013 0.0055
Loa Loa (eye worm) hypothetical protein 0.0136 0.0378 0.1842
Echinococcus multilocularis nuclear receptor subfamily 4 group A 0.0014 0.0007 0.0007
Echinococcus multilocularis roundabout 2 0.0022 0.0032 0.0032
Trypanosoma brucei GTP-binding nuclear protein rtb2, putative 0.0022 0.0031 0.0144
Loa Loa (eye worm) CMGC/CDK/CDC2 protein kinase 0.0049 0.0114 0.0556
Loa Loa (eye worm) CAMK/MLCK protein kinase 0.0027 0.0045 0.0219
Loa Loa (eye worm) hypothetical protein 0.0036 0.0073 0.0355
Brugia malayi Flap endonuclease-1 0.0054 0.0129 0.0626
Brugia malayi jmjC domain containing protein 0.0016 0.0013 0.0063
Trypanosoma brucei DNA polymerase kappa, putative 0.0163 0.0461 0.2241
Leishmania major histone deacetylase, putative 0.0561 0.1678 0.8175
Plasmodium vivax histone acetyltransferase GCN5, putative 0.0044 0.0098 0.0178
Mycobacterium ulcerans hypothetical protein 0.0034 0.0067 0.0115
Loa Loa (eye worm) flap endonuclease-1 0.0054 0.0129 0.0626
Echinococcus multilocularis serine:threonine protein kinase 12 B 0.0169 0.0479 0.0479
Toxoplasma gondii histone lysine acetyltransferase GCN5-A 0.0044 0.0098 0.0178
Schistosoma mansoni roundabout 0.0022 0.0032 0.0073
Echinococcus multilocularis H(+):Cl() exchange transporter 4 0.0021 0.0026 0.0026
Chlamydia trachomatis Mg++ transporter 0.0021 0.0026 0.004
Schistosoma mansoni cellular tumor antigen P53 0.0052 0.0122 0.0279
Echinococcus multilocularis AMPK beta subunit 0.0111 0.0302 0.0302
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0016 0.0011 0.0057
Trypanosoma cruzi chloride channel protein, putative 0.0021 0.0026 0.0119
Plasmodium vivax serine/threonine-protein kinase NEK4, putative 0.0022 0.0029 0.0051
Entamoeba histolytica casein kinase II regulatory subunit family protein 0.0038 0.0079 0.0463
Trichomonas vaginalis CAMK family protein kinase 0.0048 0.0111 0.0652
Plasmodium vivax SET domain protein, putative 0.0032 0.0062 0.0111
Echinococcus multilocularis H(+):Cl() exchange transporter 3 0.0021 0.0026 0.0026
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0032 0.0062 0.0142
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0013 0.0004 0.0012
Loa Loa (eye worm) hypothetical protein 0.0057 0.0139 0.0678
Loa Loa (eye worm) hypothetical protein 0.0014 0.0007 0.0034
Schistosoma mansoni thyroid hormone receptor 0.003 0.0056 0.0128
Echinococcus granulosus ubiquitin carboxyl terminal hydrolase 22 0.0016 0.0011 0.0026
Brugia malayi Patched related family protein 4 0.0018 0.0019 0.0094
Loa Loa (eye worm) hypothetical protein 0.034 0.1004 0.4891
Toxoplasma gondii histone deacetylase HDAC4 0.0283 0.0829 0.1524
Brugia malayi Immunoglobulin I-set domain containing protein 0.0022 0.0032 0.0155
Loa Loa (eye worm) hypothetical protein 0.0057 0.0139 0.0678
Giardia lamblia DNA damage repair protein 0.0034 0.0067 0.0373
Loa Loa (eye worm) RNA binding protein 0.0136 0.038 0.1852
Echinococcus granulosus Bcl 2 ous antagonist:killer 0.0086 0.0226 0.0518
Loa Loa (eye worm) AUR protein kinase 0.0169 0.0479 0.2335
Mycobacterium tuberculosis Probable cystathionine beta-synthase Cbs (serine sulfhydrase) (beta-thionase) (hemoprotein H-450) 0.0021 0.0026 0.0083
Plasmodium falciparum histone deacetylase 2 0.0683 0.2053 0.378
Entamoeba histolytica hypothetical protein 0.0042 0.0092 0.0539
Leishmania major 4-coumarate:coa ligase-like protein 0.0097 0.026 0.126
Mycobacterium tuberculosis Probable conserved transmembrane alanine and leucine rich protein 0.0021 0.0026 0.0083
Echinococcus multilocularis contactin neuroglian septate junction protein 0.0022 0.0032 0.0032
Plasmodium falciparum acyl-CoA synthetase 0.0073 0.0185 0.0338
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0286 0.0839 0.4994
Loa Loa (eye worm) hypothetical protein 0.0185 0.0531 0.2585
Loa Loa (eye worm) hypothetical protein 0.0022 0.0032 0.0155
Trypanosoma cruzi histone deacetylase, putative 0.0683 0.2053 1
Loa Loa (eye worm) jmjC domain-containing protein 0.0064 0.016 0.0779
Trypanosoma brucei NIMA-related protein kinase 0.0022 0.0029 0.0135
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD7 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0069 0.0173 0.0637
Loa Loa (eye worm) hypothetical protein 0.0057 0.0139 0.0678
Trichomonas vaginalis conserved hypothetical protein 0.0013 0.0004 0.0012
Mycobacterium tuberculosis POSSIBLE PARA-NITROBENZYL ESTERASE (FRAGMENT) 0.0057 0.0139 0.0509
Loa Loa (eye worm) hypothetical protein 0.0018 0.0019 0.0094
Entamoeba histolytica protein kinase domain containing protein 0.0169 0.0479 0.2849
Leishmania major serine/threonine-protein kinase, putative,protein kinase, putative 0.0189 0.0542 0.2636
Leishmania major protein kinase, putative 0.0169 0.0479 0.2329
Loa Loa (eye worm) patched family protein 0.0018 0.0019 0.0094
Onchocerca volvulus 0.0021 0.0026 0.0178
Trypanosoma brucei hypothetical protein, conserved 0.0034 0.0067 0.0318
Echinococcus multilocularis ubiquitin specific protease 41 0.0039 0.0082 0.0082
Echinococcus multilocularis nuclear receptor subfamily 1 group D 0.0016 0.0012 0.0012
Loa Loa (eye worm) hypothetical protein 0.003 0.0056 0.0272
Chlamydia trachomatis phosphoshikimate 1-carboxyl vinyltransferase 0.0294 0.0863 0.1583
Brugia malayi Voltage gated chloride channel family protein 0.0021 0.0026 0.0127
Echinococcus granulosus cyclin dependent kinase 5 0.0049 0.0114 0.0262
Loa Loa (eye worm) hypothetical protein 0.0028 0.005 0.0245
Brugia malayi orphan nuclear receptor NR2E1 0.0014 0.0007 0.0034
Loa Loa (eye worm) hypothetical protein 0.0045 0.0101 0.0492
Schistosoma mansoni cell adhesion molecule 0.0022 0.0032 0.0073
Brugia malayi phosphofructokinase 0.0113 0.0308 0.15
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD5 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0069 0.0173 0.0637
Echinococcus granulosus cadherin EGF LAG seven pass G type receptor 0.0082 0.0214 0.049
Trichomonas vaginalis glucosylceramidase, putative 0.0166 0.0472 0.2808
Mycobacterium ulcerans hypothetical protein 0.0021 0.0026 0.004
Mycobacterium ulcerans acyl-CoA synthetase 0.0028 0.005 0.0085
Echinococcus multilocularis tumor protein p63 0.0354 0.1046 0.1046
Loa Loa (eye worm) hypothetical protein 0.0434 0.129 0.6286
Echinococcus multilocularis Nuclear hormone receptor HR96 0.0014 0.0007 0.0007
Brugia malayi GTP-binding nuclear protein RAN/TC4 0.0022 0.0031 0.0152
Trypanosoma cruzi hypothetical protein, conserved 0.0031 0.0057 0.0271
Plasmodium vivax replication factor C subunit 1, putative 0.0031 0.0057 0.0102
Brugia malayi Latrophilin receptor protein 2 0.0082 0.0214 0.1042
Loa Loa (eye worm) hypothetical protein 0.0022 0.0032 0.0155
Schistosoma mansoni hypothetical protein 0.0086 0.0226 0.0518
Echinococcus granulosus mixed lineage leukemia protein mll 0.0016 0.0011 0.0025
Entamoeba histolytica serine/threonine- protein kinase 6 , putative 0.0169 0.0479 0.2849
Schistosoma mansoni hypothetical protein 0.083 0.2503 0.5738
Schistosoma mansoni serine/threonine protein kinase 0.0048 0.0111 0.0254
Echinococcus multilocularis tyrosine protein kinase otk 0.0022 0.0032 0.0032
Schistosoma mansoni chloride channel protein 0.0021 0.0026 0.006
Trichomonas vaginalis DNA polymerase eta, putative 0.0163 0.0461 0.2742
Trichomonas vaginalis histone deacetylase, putative 0.0561 0.1678 1
Echinococcus granulosus GTP binding nuclear protein Ran 0.0022 0.0031 0.0072
Loa Loa (eye worm) ImpB/MucB/SamB family protein 0.0109 0.0297 0.1449
Echinococcus multilocularis cyclin dependent kinase 0.0049 0.0114 0.0114
Plasmodium falciparum ubiquitin carboxyl-terminal hydrolase 13, putative 0.0016 0.0011 0.0018
Loa Loa (eye worm) TK/ROR protein kinase 0.0017 0.0014 0.0069
Brugia malayi Nuclear hormone receptor family member nhr-41 0.003 0.0056 0.0272
Echinococcus multilocularis casein kinase ii subunit beta 0.0038 0.0079 0.0079
Trypanosoma cruzi DNA polymerase kappa, putative 0.0163 0.0461 0.2241
Loa Loa (eye worm) AMP-binding enzyme family protein 0.0028 0.005 0.0245
Giardia lamblia Casein kinase II beta chain 0.0038 0.0079 0.0447
Echinococcus multilocularis roundabout 2 0.0058 0.0141 0.0141
Onchocerca volvulus 0.0057 0.0139 0.0952
Trypanosoma brucei hypothetical protein, conserved 0.0014 0.0006 0.0022
Echinococcus granulosus histone deacetylase 3 0.0561 0.1678 0.3847
Entamoeba histolytica protein kinase, putative 0.0189 0.0542 0.3225
Echinococcus granulosus serine:threonine protein kinase Nek1 0.0017 0.0016 0.0037
Leishmania major protein kinase, putative,SNF1-related protein kinases, putative 0.0048 0.0111 0.0533
Entamoeba histolytica protein kinase, putative 0.0169 0.0479 0.2849
Mycobacterium leprae PROBABLE FATTY-ACID-CoA LIGASE FADD7 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) 0.0097 0.026 0.0889
Schistosoma mansoni rab geranylgeranyl transferase alpha subunit 0.0109 0.0297 0.0682
Giardia lamblia Replication factor C, subunit 1 0.0031 0.0057 0.0315
Loa Loa (eye worm) hypothetical protein 0.0018 0.0019 0.0094
Echinococcus multilocularis twitchin 0.0016 0.0013 0.0013
Loa Loa (eye worm) hypothetical protein 0.0016 0.0013 0.0063
Giardia lamblia Ubiquitin carboxyl-terminal hydrolase 14 0.0016 0.0011 0.0041
Leishmania major dihydrolipoamide dehydrogenase, putative 0.0013 0.0004 0.0014
Trypanosoma cruzi ATP-dependent DEAD/H DNA helicase recQ, putative 0.0021 0.0026 0.0119
Mycobacterium tuberculosis Possible fatty-acid-CoA ligase FadD1 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0028 0.005 0.0175
Brugia malayi hypothetical protein 0.0016 0.0012 0.0059
Toxoplasma gondii 6-phosphofructokinase 0.003 0.0056 0.0101
Trypanosoma cruzi mitochondrial DNA polymerase beta-PAK, putative 0.0147 0.0413 0.2003
Trichomonas vaginalis CAMK family protein kinase 0.0022 0.0029 0.0165
Toxoplasma gondii CBS domain-containing protein 0.0021 0.0026 0.0045
Brugia malayi Patched protein homolog 1 0.0018 0.0019 0.0094
Loa Loa (eye worm) RecQ helicase 0.0021 0.0026 0.0127
Leishmania major importin beta-1 subunit, putative 0.0024 0.0038 0.0178
Trichomonas vaginalis conserved hypothetical protein 0.0013 0.0004 0.0012
Entamoeba histolytica hypothetical protein 0.0024 0.0038 0.0218
Loa Loa (eye worm) histone deacetylase 7A 0.0683 0.2053 1
Trichomonas vaginalis phosphofructokinase, putative 0.003 0.0056 0.0326
Plasmodium vivax 6-phosphofructokinase, putative 0.003 0.0056 0.0101
Trichomonas vaginalis glucosylceramidase, putative 0.0254 0.0739 0.44
Onchocerca volvulus 0.0018 0.0019 0.0131
Loa Loa (eye worm) hypothetical protein 0.0014 0.0007 0.0034
Loa Loa (eye worm) hypothetical protein 0.0018 0.0019 0.0094
Trypanosoma cruzi apurinic/apyrimidinic endonuclease, putative 0.0019 0.0023 0.0103
Loa Loa (eye worm) CAMK/CAMKL/BRSK protein kinase 0.0048 0.0111 0.054
Brugia malayi ecdysone receptor 0.0014 0.0007 0.0034
Schistosoma mansoni serine/threonine protein kinase 0.0049 0.0114 0.0262
Giardia lamblia Histone acetyltransferase GCN5 0.004 0.0087 0.0494
Echinococcus granulosus phd:f box containing protein 0.0016 0.0013 0.003
Leishmania major 4-coumarate:coa ligase-like protein 0.0097 0.026 0.126
Toxoplasma gondii pyruvate dehydrogenase complex subunit PDH-E3II 0.0013 0.0004 0.0005
Trypanosoma cruzi DNA polymerase beta thumb, putative 0.0044 0.0097 0.0463
Trypanosoma cruzi Serine/threonine-protein kinase NEK16, putative 0.0022 0.0029 0.0135
Echinococcus granulosus acetylcholinesterase 0.034 0.1004 0.2302
Brugia malayi ImpB/MucB/SamB family protein 0.0136 0.0378 0.1842
Loa Loa (eye worm) CMGC/GSK protein kinase 0.0051 0.0119 0.058
Trypanosoma brucei GMP reductase 0.0021 0.0026 0.0119
Echinococcus granulosus contactin 0.0022 0.0032 0.0073
Loa Loa (eye worm) hypothetical protein 0.0018 0.0019 0.0094
Loa Loa (eye worm) hypothetical protein 0.0018 0.0019 0.0094
Brugia malayi Importin beta-1 subunit 0.003 0.0056 0.0271
Brugia malayi nuclear hormone receptor family member nhr-6 0.0014 0.0007 0.0034
Echinococcus multilocularis thioredoxin glutathione reductase 0.0039 0.0084 0.0084
Trypanosoma cruzi JmjC domain, hydroxylase, putative 0.0016 0.0013 0.0055
Trypanosoma cruzi chloride channel protein, putative 0.0021 0.0026 0.0119
Loa Loa (eye worm) hypothetical protein 0.0018 0.0019 0.0094
Echinococcus multilocularis lysine specific demethylase 6a 0.0016 0.0013 0.0013
Echinococcus multilocularis retinoic acid receptor rxr beta a retinoic acid receptor rxr alpha a retinoic acid receptor rxr alpha 0.0014 0.0007 0.0007
Echinococcus multilocularis receptor type tyrosine protein phosphatase 0.0022 0.0032 0.0032
Trichomonas vaginalis glucosylceramidase, putative 0.0166 0.0472 0.2808
Trypanosoma cruzi hypothetical protein, conserved 0.0034 0.0067 0.0318
Trypanosoma brucei mitochondrial DNA polymerase beta 0.031 0.0913 0.4441
Trypanosoma brucei DNA polymerase kappa, putative 0.0089 0.0234 0.1135
Treponema pallidum diphosphate--fructose-6-phosphate 1-phosphotransferase 0.003 0.0056 0.0622
Brugia malayi ATP-dependent DNA helicase, RecQ family protein 0.0021 0.0026 0.0127
Schistosoma mansoni alkaline phosphatase 0.0169 0.0479 0.1098
Mycobacterium tuberculosis Possible fatty-acid-CoA ligase FadD10 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0028 0.005 0.0175
Echinococcus granulosus lysine specific demethylase 6a 0.0016 0.0013 0.003
Echinococcus granulosus titin 0.0016 0.0013 0.003
Loa Loa (eye worm) nuclear hormone receptor family member nhr-14 0.003 0.0056 0.0272
Loa Loa (eye worm) hypothetical protein 0.0014 0.0006 0.003
Echinococcus multilocularis neuroglian 0.0048 0.011 0.011
Plasmodium falciparum flap endonuclease 1 0.0054 0.0129 0.0234
Trypanosoma cruzi GTP-binding nuclear protein rtb2, putative 0.0022 0.0031 0.0144
Trypanosoma brucei aurora B kinase 0.0169 0.0479 0.2329
Brugia malayi ancient conserved domain protein 2 0.0021 0.0026 0.0127
Brugia malayi Calcitonin receptor-like protein seb-1 0.0259 0.0756 0.368
Trypanosoma cruzi histone deacetylase, putative 0.0683 0.2053 1
Trypanosoma cruzi cdc2-related kinase 3 0.0049 0.0114 0.0549
Loa Loa (eye worm) TK protein kinase 0.0017 0.0014 0.0069
Toxoplasma gondii NEK kinase 0.0022 0.0029 0.0051
Entamoeba histolytica protein kinase , putative 0.0169 0.0479 0.2849
Loa Loa (eye worm) hypothetical protein 0.0018 0.0019 0.0094
Wolbachia endosymbiont of Brugia malayi UDP-N-acetylglucosamine 1-carboxyvinyltransferase 0.018 0.0513 1
Echinococcus multilocularis titin 0.0016 0.0013 0.0013
Trichomonas vaginalis 6-phosphofructokinase, putative 0.003 0.0056 0.0326
Echinococcus granulosus neuroligin 0.0057 0.0139 0.0319
Echinococcus granulosus histone deacetylase 0.0683 0.2053 0.4706
Schistosoma mansoni hypothetical protein 0.0088 0.0231 0.053
Brugia malayi serine/threonine kinase 12 0.0169 0.0479 0.2335
Trichomonas vaginalis CAMK family protein kinase 0.0048 0.0111 0.0652
Loa Loa (eye worm) oxidoreductase 0.0028 0.005 0.0245
Loa Loa (eye worm) hypothetical protein 0.0016 0.0012 0.0059
Brugia malayi Carboxylesterase family protein 0.034 0.1004 0.4891
Onchocerca volvulus 0.0097 0.026 0.178
Toxoplasma gondii histone lysine methyltransferase SET/SUV39 0.0032 0.0062 0.0111
Loa Loa (eye worm) hypothetical protein 0.0018 0.0019 0.0094
Echinococcus granulosus histone deacetylase 6 0.0683 0.2053 0.4706
Leishmania major acetyl-CoA synthetase, putative 0.0028 0.005 0.0238
Brugia malayi Immunoglobulin I-set domain containing protein 0.0022 0.0032 0.0155
Schistosoma mansoni serine/threonine protein kinase 0.0016 0.0013 0.003
Brugia malayi Nuclear hormone receptor-like 1 0.0016 0.0012 0.0059
Plasmodium vivax dihydrolipoyl dehydrogenase, apicoplast, putative 0.0013 0.0004 0.0005
Entamoeba histolytica deoxycytidyl transferase, putative 0.0109 0.0297 0.1764
Schistosoma mansoni ubiquitin-specific peptidase 2 (C19 family) 0.0039 0.0082 0.0187
Plasmodium falciparum acetyl-CoA synthetase, putative 0.0028 0.005 0.009
Wolbachia endosymbiont of Brugia malayi IMP dehydrogenase 0.0021 0.0026 0.0425
Trypanosoma cruzi Casein kinase II subunit beta, putative 0.0038 0.0079 0.0378
Brugia malayi Protein kinase domain containing protein 0.0189 0.0542 0.2642
Loa Loa (eye worm) nuclear hormone receptor family member nhr-40 0.003 0.0056 0.0272
Loa Loa (eye worm) jmjC domain-containing protein 0.0016 0.0013 0.0063
Trichomonas vaginalis casein kinase II beta chain, putative 0.0038 0.0079 0.0463
Echinococcus granulosus microtubule associated protein 2 0.1438 0.4363 1
Brugia malayi nuclear receptor NHR-88 0.003 0.0056 0.0272
Schistosoma mansoni cyclin-dependent kinase 5 activator 0.027 0.079 0.181
Loa Loa (eye worm) nucleolar RNA-associated protein alpha 0.0322 0.095 0.4625
Toxoplasma gondii aurora kinase 0.0169 0.0479 0.088
Echinococcus multilocularis ATP dependent DNA helicase Q5 0.0021 0.0026 0.0026
Chlamydia trachomatis CBS domain-containing protein 0.0021 0.0026 0.004
Schistosoma mansoni ap endonuclease 0.0019 0.0023 0.0052
Toxoplasma gondii LsmAD domain-containing protein 0.0051 0.012 0.0218
Loa Loa (eye worm) hypothetical protein 0.0036 0.0073 0.0355
Mycobacterium ulcerans glutaminase 0.0552 0.1652 0.3037
Entamoeba histolytica phosphofructokinase, putative 0.0113 0.0308 0.1827
Echinococcus multilocularis Bcl 2 ous antagonist:killer 0.0086 0.0226 0.0226
Treponema pallidum hemolysin (tlyC) 0.0021 0.0026 0.0259
Plasmodium vivax histone deacetylase 2, putative 0.0683 0.2053 0.378
Echinococcus multilocularis JmjC domain containing protein 4 0.0016 0.0013 0.0013
Schistosoma mansoni histone-lysine n-methyltransferase suv9 0.0032 0.0062 0.0142
Onchocerca volvulus 0.0028 0.005 0.0345
Trypanosoma brucei DNA damage repair protein, putative 0.0034 0.0067 0.0318
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0016 0.0011 0.0057
Loa Loa (eye worm) hypothetical protein 0.0073 0.0185 0.0902
Mycobacterium ulcerans transcriptional regulator 0.0021 0.0026 0.004
Echinococcus granulosus histone lysine N methyltransferase MLL3 0.0016 0.0011 0.0025
Echinococcus granulosus family S9 non peptidase ue S09 family 0.0057 0.0139 0.0319
Mycobacterium ulcerans 3-phosphoshikimate 1-carboxyvinyltransferase 0.0294 0.0863 0.1583
Schistosoma mansoni histone deacetylase 4 5 0.0683 0.2053 0.4706
Loa Loa (eye worm) hypothetical protein 0.0036 0.0073 0.0355
Trypanosoma brucei chrX additional, unordered contigs 0.0034 0.0067 0.0318
Brugia malayi hypothetical protein 0.0018 0.0019 0.0094
Toxoplasma gondii hypothetical protein 0.005 0.0116 0.0211
Giardia lamblia DINP protein human, muc B family 0.0123 0.0338 0.1993
Toxoplasma gondii exonuclease III APE 0.0019 0.0023 0.0039
Treponema pallidum DNA ligase (lig) 0.0031 0.0057 0.0632
Trypanosoma cruzi Casein kinase II subunit beta, putative 0.0038 0.0079 0.0378
Trichomonas vaginalis glucosylceramidase, putative 0.0166 0.0472 0.2808
Toxoplasma gondii cell-cycle-associated protein kinase CDK, putative 0.0049 0.0114 0.0208
Trypanosoma brucei DNA polymerase kappa, putative 0.0163 0.0461 0.2241
Echinococcus granulosus nuclear receptor 2DBD gamma 0.003 0.0056 0.0128
Entamoeba histolytica phosphofructokinase, putative 0.0113 0.0308 0.1827
Echinococcus multilocularis GA binding protein alpha chain 0.0071 0.0181 0.0181
Brugia malayi Carboxylesterase family protein 0.034 0.1004 0.4891
Brugia malayi hypothetical protein 0.0031 0.0057 0.0279
Trichomonas vaginalis AGC family protein kinase 0.0169 0.0479 0.2849
Schistosoma mansoni 6-phosphofructokinase 0.0113 0.0308 0.0706
Loa Loa (eye worm) hypothetical protein 0.0073 0.0185 0.0902
Echinococcus granulosus para nitrobenzyl esterase 0.0057 0.0139 0.0319
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0013 0.0004 0.0014
Trypanosoma brucei apurinic/apyrimidinic endonuclease, putative 0.0019 0.0023 0.0103
Schistosoma mansoni ubiquitin-specific peptidase 44 (C19 family) 0.0016 0.0011 0.0026
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0013 0.0004 0.0012
Mycobacterium tuberculosis Conserved hypothetical membrane protein 0.0021 0.0026 0.0083
Trichomonas vaginalis histone deacetylase, putative 0.0561 0.1678 1
Plasmodium vivax serine/threonine-protein kinase Nek1, putative 0.0022 0.0029 0.0051
Loa Loa (eye worm) hypothetical protein 0.0018 0.0019 0.0094
Brugia malayi Ets-domain containing protein 0.0071 0.0181 0.0881
Plasmodium vivax histone deacetylase, putative 0.0283 0.0829 0.1524
Schistosoma mansoni chloride channel protein 0.0021 0.0026 0.006
Mycobacterium ulcerans non-ribosomal peptide synthetase MbtE 0.0028 0.005 0.0085
Echinococcus granulosus DNA apurinic or apyrimidinic site lyase 0.0019 0.0023 0.0052
Brugia malayi Myosin head containing protein 0.0018 0.0019 0.0094
Entamoeba histolytica protein kinase, putative 0.0189 0.0542 0.3225
Echinococcus granulosus muscleblind protein 0.0611 0.1834 0.4204
Toxoplasma gondii patched family protein 0.0018 0.0019 0.0032
Echinococcus granulosus cpg binding protein 0.0062 0.0152 0.0348
Leishmania major hypothetical protein, conserved,leucine-rich repeat protein, putative 0.0014 0.0006 0.0022
Loa Loa (eye worm) CAMK/CAMKL/AMPK protein kinase 0.0236 0.0685 0.3339
Schistosoma mansoni flap endonuclease-1 0.0049 0.0113 0.0258
Loa Loa (eye worm) hypothetical protein 0.0021 0.0026 0.0127
Plasmodium falciparum histone deacetylase, putative 0.0683 0.2053 0.378
Schistosoma mansoni family C19 non-peptidase homologue (C19 family) 0.0016 0.0011 0.0026
Brugia malayi Protein kinase domain containing protein 0.0049 0.0114 0.0556
Mycobacterium tuberculosis Conserved protein 0.0021 0.0026 0.0083
Loa Loa (eye worm) patched family protein 0.0018 0.0019 0.0094
Trypanosoma cruzi Domain of unknown function DUF21, putative 0.0021 0.0026 0.0119
Loa Loa (eye worm) hypothetical protein 0.034 0.1004 0.4891
Echinococcus granulosus replication factor c subunit 1 0.0031 0.0057 0.0131
Echinococcus multilocularis neurotracting:lsamp:neurotrimin:obcam 0.0022 0.0032 0.0032
Loa Loa (eye worm) immunoglobulin I-set domain-containing protein 0.0022 0.0032 0.0155
Giardia lamblia Flap structure-specific endonuclease 0.0054 0.0129 0.0741
Mycobacterium leprae Probable fructose bisphosphate aldolase Fba 0.014 0.0391 0.1387
Loa Loa (eye worm) histone deacetylase 11 0.0283 0.0829 0.4036
Schistosoma mansoni photoreceptor-specific nuclear receptor related 0.003 0.0056 0.0128
Trypanosoma brucei histone deacetylase, putative 0.0683 0.2053 1
Echinococcus multilocularis 5' AMP activated protein kinase subunit gamma 0.0228 0.0661 0.0661
Toxoplasma gondii shikimate dehydrogenase substrate binding domain-containing protein 0.0294 0.0863 0.1587
Entamoeba histolytica cell division protein kinase 2, putative 0.0049 0.0114 0.0672
Echinococcus multilocularis ecdysone induced protein 78C 0.003 0.0056 0.0056
Schistosoma mansoni histone deacetylase 0.0561 0.1678 0.3847
Brugia malayi Ubiquitin carboxyl-terminal hydrolase family protein 0.0039 0.0082 0.0398
Toxoplasma gondii ATP-dependent DNA helicase, RecQ family protein 0.0021 0.0026 0.0045
Onchocerca volvulus Bile acid receptor homolog 0.003 0.0056 0.0383
Schistosoma mansoni phd/f-box containing protein 0.0016 0.0013 0.003
Echinococcus granulosus macrophage colony stimulating factor 1 receptor 0.0551 0.1648 0.3777
Loa Loa (eye worm) hypothetical protein 0.0157 0.0442 0.2155
Echinococcus granulosus cyclin dependent kinase 5 activator 1 0.027 0.079 0.181
Trypanosoma cruzi DNA polymerase eta, putative 0.006 0.0148 0.0712
Trichomonas vaginalis CAMK family protein kinase 0.0048 0.0111 0.0652
Brugia malayi polk-prov protein 0.0088 0.0231 0.1125
Echinococcus granulosus GA binding protein alpha chain 0.0071 0.0181 0.0415
Brugia malayi AMP-binding enzyme family protein 0.0028 0.005 0.0245
Onchocerca volvulus 0.0014 0.0007 0.0048
Mycobacterium leprae Chorismate synthase AroF (5-enolpyruvylshikimate-3-phosphate phospholyase). 0.0881 0.2658 1
Brugia malayi Ubiquitin carboxyl-terminal hydrolase family protein 0.0016 0.0011 0.0055
Echinococcus multilocularis para nitrobenzyl esterase 0.0057 0.0139 0.0139
Trichomonas vaginalis CMGC family protein kinase 0.0051 0.0119 0.07
Brugia malayi hypothetical protein 0.0031 0.0057 0.0279
Loa Loa (eye worm) BRCA1-associated protein 2 containing protein 0.0013 0.0002 0.0008
Brugia malayi Corticotropin releasing factor receptor 2 precursor, putative 0.0259 0.0756 0.368
Loa Loa (eye worm) hypothetical protein 0.0036 0.0073 0.0355
Echinococcus multilocularis histone lysine N methyltransferase MLL3 0.0016 0.0011 0.0011
Brugia malayi Apoptosis regulator proteins, Bcl-2 family protein 0.0086 0.0226 0.11
Echinococcus granulosus terminal deoxycytidyl transferase rev1 0.0109 0.0297 0.0682
Echinococcus granulosus dual specificity 0.0189 0.0542 0.1243
Brugia malayi Patched family protein 0.0018 0.0019 0.0094
Giardia lamblia Pyrophosphate-fructose 6-phosphate 1-phosphotransferase alpha subunit 0.003 0.0056 0.031
Brugia malayi nuclear receptor RXR 0.0016 0.0012 0.0059
Trypanosoma brucei DNA polymerase kappa, putative 0.0089 0.0234 0.1135
Trypanosoma brucei histone deacetylase 2 0.0283 0.0829 0.4032
Plasmodium vivax 6-phosphofructokinase, putative 0.003 0.0056 0.0101
Trichomonas vaginalis DNA polymerase IV / kappa, putative 0.0163 0.0461 0.2742
Echinococcus multilocularis roundabout 2 0.0022 0.0032 0.0032
Trichomonas vaginalis glucosylceramidase, putative 0.0254 0.0739 0.44

Activities

Activity type Activity value Assay description Source Reference
clogP = 3.426 Calculated partition coefficient (clogP) ChEMBL. 12657285
MIC (functional) = 3.13 ug ml-1 In vitro antibacterial activity against Pasteurella multocida 59A0067 ChEMBL. 12657285
MIC (functional) = 6.25 ug ml-1 In vitro antibacterial activity against Staphylococcus aureus 01A0758 ChEMBL. 12657285
MIC (functional) = 50 ug ml-1 In vitro antibacterial activity against Escherichia coli 51A0150 ChEMBL. 12657285
MIC (functional) = 50 ug ml-1 In vitro antibacterial activity against Escherichia coli 51A0150 ChEMBL. 12657285

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
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External resources for this compound

Bibliographic References

1 literature reference was collected for this gene.

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