Detailed information for compound 38730

Basic information

Technical information
  • TDR Targets ID: 38730
  • Name: N-(2-morpholin-4-ylethyl)-5-nitroquinolin-4-a mine
  • MW: 302.328 | Formula: C15H18N4O3
  • H donors: 1 H acceptors: 3 LogP: 1.67 Rotable bonds: 5
    Rule of 5 violations (Lipinski): 1
  • SMILES: [O-][N+](=O)c1cccc2c1c(NCCN1CCOCC1)ccn2
  • InChi: 1S/C15H18N4O3/c20-19(21)14-3-1-2-12-15(14)13(4-5-16-12)17-6-7-18-8-10-22-11-9-18/h1-5H,6-11H2,(H,16,17)
  • InChiKey: VKHMFWMEBRXYIW-UHFFFAOYSA-N  

Network

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Synonyms

  • N-(2-morpholinoethyl)-5-nitro-quinolin-4-amine
  • N-(2-morpholinoethyl)-5-nitro-4-quinolinamine
  • N-(2-morpholin-4-ylethyl)-5-nitro-quinolin-4-amine
  • 2-morpholinoethyl-(5-nitro-4-quinolyl)amine
  • N-[4-(2-morpholin-4-ylethylamino)quinolin-5-yl]-N-oxidohydroxylamine
  • N-[4-(2-morpholinoethylamino)-5-quinolyl]-N-oxido-hydroxylamine
  • N-[4-(2-morpholinoethylamino)-5-quinolyl]-N-oxidohydroxylamine
  • N-[4-(2-morpholin-4-ylethylamino)quinolin-5-yl]-N-oxido-hydroxylamine
  • 5-(Hydroxy(oxido)amino)-4-((2-(4-morpholinyl)ethyl)amino)quinoline hydrochloride
  • AIDS-157624
  • AIDS157624
  • NSC646859 (HYDROCHLORIDE SALT)
  • NCI60_016203

Targets

Known targets for this compound

No curated genes were found associated with this compound

Predicted pathogen targets for this compound

By orthology
No druggable targets predicted by orthology data
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity

Obtained from network model

Ranking Plot


Putative Targets List


Species Potential target Raw Global Species
Echinococcus multilocularis basement membrane specific heparan sulfate 0.0036 0.0069 0.0073
Echinococcus granulosus tyrosine protein kinase otk 0.0022 0.003 0.0073
Onchocerca volvulus 0.0052 0.0115 0.0832
Plasmodium falciparum chorismate synthase 0.3457 1 1
Echinococcus granulosus para nitrobenzyl esterase 0.0046 0.0099 0.0239
Loa Loa (eye worm) GTP-binding nuclear protein RAN/TC4 0.0022 0.003 0.0155
Leishmania major histone deacetylase, putative 0.0551 0.1565 0.8169
Echinococcus granulosus 5' AMP activated protein kinase subunit beta 1 0.0059 0.0138 0.0332
Toxoplasma gondii ATP-dependent DNA helicase, RecQ family protein 0.0021 0.0025 0.0024
Schistosoma mansoni histone deacetylase 1 2 3 0.0278 0.0773 0.1867
Schistosoma mansoni receptor tyrosine phosphatase type r2a 0.0022 0.003 0.0073
Brugia malayi Niemann-Pick C1 protein precursor 0.0302 0.0841 0.4392
Trypanosoma brucei DNA polymerase IV, putative 0.015 0.0399 0.208
Schistosoma mansoni gliotactin 0.0046 0.0099 0.0239
Schistosoma mansoni histone deacetylase hda2 0.0684 0.1951 0.4714
Trypanosoma brucei DNA polymerase kappa, putative 0.0163 0.0438 0.2282
Loa Loa (eye worm) hypothetical protein 0.0058 0.0134 0.0701
Brugia malayi hypothetical protein 0.0018 0.0018 0.0095
Trichomonas vaginalis CMGC family protein kinase 0.0048 0.0104 0.0658
Trypanosoma cruzi mitochondrial DNA polymerase beta, putative 0.031 0.0866 0.4517
Mycobacterium tuberculosis Conserved hypothetical membrane protein 0.0021 0.0025 0.0043
Brugia malayi Immunoglobulin I-set domain containing protein 0.0524 0.1486 0.7758
Mycobacterium tuberculosis Carboxylesterase LipT 0.0046 0.0099 0.0194
Brugia malayi Nuclear hormone receptor-like 1 0.0016 0.0012 0.006
Onchocerca volvulus 0.0028 0.0048 0.0345
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0286 0.0796 0.5077
Echinococcus granulosus Nuclear hormone receptor HR96 0.0014 0.0007 0.0016
Loa Loa (eye worm) nuclear receptor NHR-67 0.0014 0.0007 0.0034
Brugia malayi Voltage gated chloride channel family protein 0.0021 0.0025 0.0129
Brugia malayi AMP-binding enzyme family protein 0.0028 0.0048 0.025
Trypanosoma cruzi GTP-binding nuclear protein rtb2, putative 0.0022 0.003 0.015
Trypanosoma cruzi mitochondrial DNA polymerase beta, putative 0.031 0.0866 0.4517
Echinococcus granulosus neuroglian 0.0048 0.0104 0.0251
Mycobacterium ulcerans 3-dehydroquinate synthase 0.012 0.0314 0.031
Trichomonas vaginalis chromosome transmission fidelity factor, putative 0.0021 0.0025 0.0152
Loa Loa (eye worm) hypothetical protein 0.003 0.0053 0.0277
Mycobacterium tuberculosis Conserved protein 0.0021 0.0025 0.0043
Loa Loa (eye worm) chloride channel 3 0.0021 0.0025 0.0129
Echinococcus multilocularis histone deacetylase 7 0.0672 0.1915 0.2019
Trypanosoma cruzi Serine/threonine-protein kinase NEK16, putative 0.0022 0.0028 0.014
Brugia malayi ImpB/MucB/SamB family protein 0.0109 0.0282 0.1473
Loa Loa (eye worm) hypothetical protein 0.0021 0.0025 0.0129
Toxoplasma gondii histone lysine methyltransferase SET1 0.0115 0.03 0.0299
Leishmania major DNA polymerase eta, putative 0.006 0.014 0.0727
Echinococcus multilocularis u4:u6.u5 tri snrnp associated protein 2 0.0015 0.001 0.0011
Toxoplasma gondii ck2 beta subunit 0.0038 0.0075 0.0074
Trichomonas vaginalis phosphofructokinase, putative 0.0113 0.0292 0.1859
Schistosoma mansoni brca1-associated protein (brap2) 0.0012 0.0001 0.0002
Mycobacterium ulcerans acyl-CoA synthetase 0.0028 0.0048 0.0044
Trichomonas vaginalis casein kinase II beta chain, putative 0.0038 0.0075 0.0474
Trypanosoma brucei unspecified product 0.015 0.0399 0.208
Trichomonas vaginalis carboxylesterase domain containing protein, putative 0.0046 0.0099 0.0626
Loa Loa (eye worm) histone deacetylase 11 0.0278 0.0773 0.4033
Echinococcus multilocularis lachesin 0.0022 0.003 0.0032
Echinococcus granulosus histone acetyltransferase KAT2B 0.0146 0.0389 0.094
Brugia malayi DKFZp564C0469 protein 0.0021 0.0025 0.0129
Loa Loa (eye worm) hypothetical protein 0.0014 0.0007 0.0034
Schistosoma mansoni alkaline phosphatase 0.0169 0.0454 0.1098
Loa Loa (eye worm) hypothetical protein 0.0551 0.1565 0.817
Loa Loa (eye worm) hypothetical protein 0.003 0.0053 0.0277
Trypanosoma brucei long-chain-fatty-acid-CoA ligase, putative 0.0028 0.0048 0.0245
Schistosoma mansoni serine/threonine protein kinase 0.0022 0.0028 0.0067
Mycobacterium tuberculosis Probable NADH dehydrogenase Ndh 0.0089 0.0222 0.0446
Trichomonas vaginalis casein kinase II beta chain, putative 0.0038 0.0075 0.0474
Giardia lamblia Hypothetical protein 0.0015 0.001 0.0037
Loa Loa (eye worm) hypothetical protein 0.0044 0.0093 0.0484
Echinococcus multilocularis gcn5proteinral control of amino acid synthesis 0.015 0.0401 0.0423
Echinococcus granulosus glycogen synthase kinase 3 beta 0.0051 0.0113 0.0273
Brugia malayi Patched family protein 0.0018 0.0018 0.0095
Brugia malayi loechrig isoform VII 0.0228 0.0627 0.3274
Leishmania major mitochondrial DNA polymerase beta-PAK, putative 0.0147 0.0391 0.2039
Echinococcus multilocularis Ataxin 2, N terminal,domain containing protein 0.0023 0.0032 0.0033
Schistosoma mansoni ubiquitin-specific peptidase 2 (C19 family) 0.0039 0.0078 0.0187
Toxoplasma gondii flap structure-specific endonuclease 1, putative 0.0054 0.0122 0.0121
Brugia malayi Ets-domain containing protein 0.0071 0.0172 0.0896
Toxoplasma gondii histone deacetylase HDAC1 0.0672 0.1915 0.1915
Toxoplasma gondii phosphofructokinase domain-containing protein 0.003 0.0053 0.0053
Schistosoma mansoni ecdysone-induced protein 78c (dr-78) 0.0016 0.0012 0.0028
Trypanosoma brucei histone deacetylase 1 0.0551 0.1565 0.8169
Entamoeba histolytica ubiquitin carboxyl-terminal hydrolase domain containing protein 0.0039 0.0078 0.049
Loa Loa (eye worm) AMP-binding enzyme family protein 0.0028 0.0048 0.025
Onchocerca volvulus 0.0046 0.0099 0.0713
Mycobacterium ulcerans bifunctional enzyme MbtA: salicyl-AMP ligase (SAL-AMP ligase) + salicyl-S-ACP synthetase 0.0028 0.0048 0.0044
Loa Loa (eye worm) hypothetical protein 0.0014 0.0007 0.0034
Trichomonas vaginalis flap endonuclease-1, putative 0.0054 0.0122 0.0773
Trypanosoma cruzi GTP-binding nuclear protein rtb2, putative 0.0022 0.003 0.015
Loa Loa (eye worm) hypothetical protein 0.0136 0.0359 0.1873
Loa Loa (eye worm) apoptosis regulator protein 0.0086 0.0214 0.1118
Loa Loa (eye worm) hypothetical protein 0.0018 0.0018 0.0095
Echinococcus granulosus Immunoglobulin 0.0036 0.0069 0.0167
Mycobacterium tuberculosis 3-dehydroquinate synthase AroB 0.012 0.0314 0.0632
Entamoeba histolytica phosphofructokinase, putative 0.0113 0.0292 0.1862
Brugia malayi jmjC domain containing protein 0.0016 0.0012 0.0064
Leishmania major glycogen synthase kinase, putative;with=GeneDB:LinJ18_V3.0270 0.0051 0.0113 0.0585
Trypanosoma cruzi inosine-5'-monophosphate dehydrogenase, putative 0.0021 0.0025 0.0124
Brugia malayi Fibronectin type III domain containing protein 0.0036 0.0069 0.0361
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.003 0.0053 0.0277
Loa Loa (eye worm) hypothetical protein 0.0394 0.1108 0.5784
Brugia malayi Myosin head containing protein 0.0018 0.0018 0.0095
Trichomonas vaginalis histone deacetylase, putative 0.0551 0.1565 0.9987
Onchocerca volvulus 0.0018 0.0018 0.0131
Toxoplasma gondii hypothetical protein 0.005 0.011 0.0109
Brugia malayi Protein kinase domain containing protein 0.0189 0.0515 0.2686
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0013 0.0003 0.0016
Schistosoma mansoni hypothetical protein 0.0023 0.0032 0.0077
Brugia malayi dihydrolipoyl dehydrogenase, mitochondrial precursor, putative 0.0013 0.0004 0.0022
Trichomonas vaginalis CAMK family protein kinase 0.0048 0.0105 0.0666
Echinococcus granulosus 5'partial|cyclin dependent kinase 1 0.0048 0.0104 0.0251
Echinococcus granulosus diuretic hormone 44 receptor GPRdih2 0.0066 0.0155 0.0376
Echinococcus multilocularis H(+):Cl() exchange transporter 4 0.0021 0.0025 0.0026
Entamoeba histolytica pyrophosphate-dependent phosphofructokinase 0.003 0.0053 0.0336
Loa Loa (eye worm) hypothetical protein 0.0018 0.0018 0.0095
Plasmodium vivax glycogen synthase kinase 3, putative 0.0051 0.0113 0.0112
Trypanosoma cruzi histone deacetylase 1, putative 0.0551 0.1565 0.8169
Brugia malayi Pax transcription activation domain interacting protein 0.0021 0.0025 0.0129
Schistosoma mansoni Neurotrimin precursor (hNT) 0.0036 0.0069 0.0167
Trypanosoma cruzi ubiquitin carboxyl-terminal hydrolase, putative 0.0039 0.0078 0.04
Echinococcus granulosus defective proboscis extension response 0.0036 0.0069 0.0167
Schistosoma mansoni protein phosphatase 2C 0.0016 0.0012 0.003
Loa Loa (eye worm) DR-78 0.0014 0.0007 0.0034
Trypanosoma brucei Voltage-gated Chloride channel Like 3 0.0021 0.0025 0.0124
Echinococcus granulosus roundabout 2 0.0058 0.0134 0.0324
Schistosoma mansoni chloride channel protein 0.0021 0.0025 0.006
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0286 0.0796 0.5077
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0032 0.0059 0.0142
Loa Loa (eye worm) hypothetical protein 0.0018 0.0018 0.0095
Echinococcus multilocularis DNA (apurinic or apyrimidinic site) lyase 0.0019 0.0022 0.0023
Echinococcus granulosus nuclear receptor subfamily 4 group A 0.0014 0.0007 0.0016
Plasmodium falciparum NIMA related kinase 2 0.0022 0.0028 0.0027
Loa Loa (eye worm) hypothetical protein 0.0018 0.0018 0.0095
Loa Loa (eye worm) acetyltransferase 0.015 0.0401 0.2094
Onchocerca volvulus Nuclear receptor subfamily 6 group A member 1 homolog 0.0014 0.0007 0.0048
Schistosoma mansoni tar DNA-binding protein 0.0131 0.0344 0.0832
Loa Loa (eye worm) hypothetical protein 0.0046 0.0099 0.0517
Trichomonas vaginalis conserved hypothetical protein 0.0021 0.0025 0.0152
Treponema pallidum UDP-N-acetylglucosamine 1-carboxyvinyltransferase 0.0189 0.0513 0.642
Trichomonas vaginalis RNA polymerase II ctd phosphatase, putative 0.0021 0.0025 0.0152
Giardia lamblia Ubiquitin carboxyl-terminal hydrolase 14 0.0015 0.001 0.0037
Onchocerca volvulus 0.0014 0.0007 0.0048
Echinococcus granulosus sterol regulatory element binding protein 0.013 0.0341 0.0824
Plasmodium vivax casein kinase II beta chain, putative 0.0038 0.0075 0.0074
Trichomonas vaginalis casein kinase II beta chain, putative 0.0038 0.0075 0.0474
Trichomonas vaginalis CMGC family protein kinase 0.0051 0.0113 0.0715
Toxoplasma gondii patched family protein 0.0018 0.0018 0.0017
Echinococcus multilocularis hemicentin 1 0.0022 0.003 0.0032
Plasmodium falciparum ATP-dependent 6-phosphofructokinase 0.003 0.0053 0.0053
Onchocerca volvulus Protein patched homolog 0.0018 0.0018 0.0131
Brugia malayi CHE-14 protein 0.013 0.0341 0.1781
Plasmodium vivax 6-phosphofructokinase, putative 0.003 0.0053 0.0053
Echinococcus granulosus Niemann Pick C1 protein 0.0431 0.1217 0.2941
Loa Loa (eye worm) ubiquitin specific peptidase 39 0.0015 0.001 0.0052
Echinococcus granulosus ubiquitin specific protease 41 0.0039 0.0078 0.0187
Treponema pallidum diphosphate--fructose-6-phosphate 1-phosphotransferase 0.003 0.0053 0.0622
Giardia lamblia Kinase, CMGC CDK 0.0048 0.0104 0.0639
Entamoeba histolytica protein kinase domain containing protein 0.0189 0.0515 0.3284
Onchocerca volvulus Basement membrane proteoglycan homolog 0.0022 0.003 0.0218
Trichomonas vaginalis AGC family protein kinase 0.0169 0.0455 0.2898
Loa Loa (eye worm) CMGC/GSK protein kinase 0.0051 0.0113 0.0589
Entamoeba histolytica acyl-CoA synthetase, putative 0.0097 0.0247 0.1572
Leishmania major DNA polymerase eta, putative 0.0136 0.0359 0.1869
Mycobacterium tuberculosis Hypoxic response protein 1 Hrp1 0.0021 0.0025 0.0043
Brugia malayi topoisomerase 0.0021 0.0025 0.0129
Echinococcus granulosus replication factor c subunit 1 0.0021 0.0025 0.006
Schistosoma mansoni defective proboscis extension response (dpr)-related 0.0036 0.0069 0.0167
Leishmania major dihydrolipoamide dehydrogenase, putative 0.0013 0.0004 0.0017
Trypanosoma brucei importin beta-1 subunit, putative 0.003 0.0053 0.0271
Schistosoma mansoni nuclear receptor 0.0014 0.0007 0.0016
Trichomonas vaginalis casein kinase II beta chain, putative 0.0038 0.0075 0.0474
Echinococcus granulosus dihydrolipoamide dehydrogenase 0.0013 0.0004 0.001
Loa Loa (eye worm) hypothetical protein 0.0018 0.0018 0.0095
Trichomonas vaginalis CAMK family protein kinase 0.0048 0.0105 0.0666
Trichomonas vaginalis glucosylceramidase, putative 0.0166 0.0448 0.2856
Plasmodium falciparum acetyl-CoA synthetase, putative 0.0028 0.0048 0.0047
Echinococcus multilocularis 5' AMP activated protein kinase catalytic 0.0236 0.065 0.0685
Leishmania major inosine-5-monophosphate dehydrogenase 0.0021 0.0025 0.0124
Echinococcus multilocularis importin subunit beta 1 0.003 0.0053 0.0056
Trichomonas vaginalis histone deacetylase, putative 0.0551 0.1565 0.9987
Echinococcus multilocularis tyrosine protein kinase otk 0.0022 0.003 0.0032
Echinococcus granulosus histone deacetylase 8 0.0278 0.0773 0.1867
Trichomonas vaginalis CAMK family protein kinase 0.0022 0.0028 0.0171
Echinococcus multilocularis dnaJ subfamily B 0.083 0.2375 0.2503
Brugia malayi ATP dependent DNA ligase C terminal region family protein 0.0021 0.0025 0.0129
Mycobacterium leprae PROBABLE FATTY-ACID-CoA LIGASE FADD2 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) 0.0097 0.0247 0.0454
Echinococcus granulosus intestinal type alkaline phosphatase 1 0.0169 0.0454 0.1098
Trypanosoma brucei DNA polymerase kappa, putative 0.0163 0.0438 0.2282
Schistosoma mansoni ubiquitously transcribed sex (X/Y) chromosome tetratricopeptide repeat protein-related 0.0016 0.0012 0.003
Entamoeba histolytica ubiquitin carboxyl-terminal hydrolase domain containing protein 0.0015 0.001 0.0058
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0013 0.0003 0.0016
Trypanosoma cruzi CMGC/DYRK protein kinase, putative 0.0189 0.0515 0.2683
Echinococcus granulosus 6 phosphofructokinase 0.0113 0.0292 0.0706
Schistosoma mansoni hepatocyte nuclear factor 4-alpha (hnf-4-alpha) 0.0014 0.0007 0.0016
Plasmodium vivax thioredoxin reductase, putative 0.0039 0.0078 0.0077
Trypanosoma brucei DNA polymerase kappa, putative 0.0163 0.0438 0.2282
Schistosoma mansoni cpg binding protein 0.0062 0.0144 0.0348
Trichomonas vaginalis glucosylceramidase, putative 0.0166 0.0448 0.2856
Brugia malayi Pre-SET motif family protein 0.0217 0.0595 0.3106
Leishmania major chloride channel protein, putative 0.0021 0.0025 0.0124
Mycobacterium ulcerans glutaminase 0.0552 0.1567 0.1564
Toxoplasma gondii hypothetical protein 0.0018 0.0018 0.0017
Echinococcus multilocularis GTP binding nuclear protein Ran 0.0022 0.003 0.0031
Brugia malayi Patched family protein 0.0018 0.0018 0.0095
Brugia malayi Muscleblind-like protein 0.0611 0.174 0.9084
Mycobacterium tuberculosis Possible DNA-damage-inducible protein P DinP (DNA polymerase V) (pol IV 2) (DNA nucleotidyltransferase (DNA-directed)) 0.0123 0.0321 0.0646
Loa Loa (eye worm) hypothetical protein 0.0142 0.0376 0.1965
Trichomonas vaginalis CAMK family protein kinase 0.0048 0.0105 0.0666
Toxoplasma gondii poly(ADP-ribose) polymerase catalytic domain-containing protein 0.0021 0.0025 0.0024
Trichomonas vaginalis phosphofructokinase, putative 0.0113 0.0292 0.1859
Echinococcus multilocularis 5' AMP activated protein kinase subunit gamma 0.0208 0.0568 0.0598
Entamoeba histolytica acyl-coA synthetase, putative 0.0097 0.0247 0.1572
Loa Loa (eye worm) hypothetical protein 0.0018 0.0018 0.0095
Brugia malayi Nuclear hormone receptor-like 1 0.0016 0.0012 0.006
Trichomonas vaginalis ap endonuclease, putative 0.0019 0.0022 0.0133
Brugia malayi Immunoglobulin I-set domain containing protein 0.0022 0.003 0.0158
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD2 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0097 0.0247 0.0495
Plasmodium vivax histone deacetylase, putative 0.0672 0.1915 0.1915
Trichomonas vaginalis DNA helicase recq, putative 0.0021 0.0025 0.0152
Onchocerca volvulus Tyrosine kinase homolog 0.049 0.1387 1
Loa Loa (eye worm) hypothetical protein 0.0046 0.0099 0.0518
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0013 0.0004 0.0017
Trypanosoma cruzi hypothetical protein, conserved 0.0034 0.0063 0.0327
Echinococcus granulosus contactin 0.0022 0.003 0.0073
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0013 0.0004 0.0017
Toxoplasma gondii IQ calmodulin-binding motif domain-containing protein 0.0014 0.0006 0.0005
Entamoeba histolytica fructose-1,6-bisphosphate aldolase, putative 0.0286 0.0796 0.5084
Echinococcus granulosus histone deacetylase 1 0.0551 0.1565 0.3781
Plasmodium falciparum serine/threonine protein kinase KIN 0.0048 0.0105 0.0104
Schistosoma mansoni nuclear hormone receptor 0.0014 0.0007 0.0016
Loa Loa (eye worm) jmjC domain-containing protein 0.0016 0.0012 0.0064
Trichomonas vaginalis casein kinase II beta chain, putative 0.0038 0.0075 0.0474
Echinococcus granulosus serine:threonine protein kinase Nek1 0.0017 0.0015 0.0037
Trichomonas vaginalis histone deacetylase, putative 0.0551 0.1565 0.9987
Brugia malayi AMP-binding enzyme family protein 0.0028 0.0048 0.025
Echinococcus multilocularis histone deacetylase 8 0.0278 0.0773 0.0814
Mycobacterium tuberculosis Dihydrolipoamide dehydrogenase LpdC (lipoamide reductase (NADH)) (lipoyl dehydrogenase) (dihydrolipoyl dehydrogenase) (diaphoras 0.0099 0.0251 0.0504
Trichomonas vaginalis casein kinase II beta chain, putative 0.0038 0.0075 0.0474
Schistosoma mansoni flap endonuclease-1 0.0049 0.0107 0.0258
Brugia malayi 5'-AMP-activated protein kinase, beta subunit, complex-interacting region containing protein 0.0111 0.0287 0.1496
Brugia malayi hypothetical protein 0.0016 0.0012 0.006
Echinococcus granulosus dna polymerase kappa 0.0163 0.0438 0.1058
Trypanosoma cruzi chloride channel protein, putative 0.0021 0.0025 0.0124
Loa Loa (eye worm) hypothetical protein 0.0278 0.0773 0.4033
Leishmania major trypanothione reductase 0.0039 0.0078 0.0402
Loa Loa (eye worm) immunoglobulin I-set domain-containing protein 0.0022 0.003 0.0158
Loa Loa (eye worm) hypothetical protein 0.0016 0.0012 0.0064
Loa Loa (eye worm) hypothetical protein 0.013 0.0341 0.1781
Giardia lamblia Replication factor C, subunit 1 0.0021 0.0025 0.0131
Loa Loa (eye worm) hypothetical protein 0.0018 0.0018 0.0095
Trypanosoma cruzi cdc2-related kinase 3 0.0048 0.0104 0.0538
Echinococcus granulosus JmjC domain containing protein 4 0.0016 0.0012 0.003
Trichomonas vaginalis casein kinase II beta chain, putative 0.0038 0.0075 0.0474
Plasmodium vivax 6-phosphofructokinase, putative 0.003 0.0053 0.0053
Mycobacterium tuberculosis Probable reductase 0.0089 0.0222 0.0446
Onchocerca volvulus 0.0018 0.0018 0.0131
Loa Loa (eye worm) hypothetical protein 0.0014 0.0006 0.003
Loa Loa (eye worm) hypothetical protein 0.0018 0.0018 0.0095
Echinococcus multilocularis cyclin dependent kinase 1 0.0048 0.0104 0.011
Leishmania major 2-oxoglutarate dehydrogenase, e3 component, lipoamidedehydrogenase-like protein 0.0013 0.0004 0.0017
Brugia malayi Nuclear hormone receptor E75 0.0014 0.0007 0.0034
Trypanosoma cruzi SNF1-related protein kinases, putative 0.0048 0.0105 0.0545
Mycobacterium ulcerans acyl-CoA synthetase 0.0097 0.0247 0.0243
Echinococcus multilocularis dna polymerase eta 0.0136 0.0359 0.0378
Leishmania major protein kinase, putative,SNF1-related protein kinases, putative 0.0048 0.0105 0.0545
Trypanosoma cruzi histone deacetylase, putative 0.0278 0.0773 0.4031
Echinococcus multilocularis bloom syndrome protein 0.0021 0.0025 0.0026
Toxoplasma gondii BRCA1 C Terminus (BRCT) domain-containing protein 0.0047 0.0102 0.0101
Loa Loa (eye worm) hypothetical protein 0.0018 0.0018 0.0095
Trichomonas vaginalis ran, putative 0.0022 0.003 0.0183
Echinococcus multilocularis sterol regulatory element binding protein 0.013 0.0341 0.036
Schistosoma mansoni AMP-activated protein kinase gamma regulatory subunit 0.0021 0.0025 0.006
Toxoplasma gondii histone lysine acetyltransferase GCN5-B 0.0044 0.0093 0.0092
Trypanosoma cruzi histone deacetylase, putative 0.0278 0.0773 0.4031
Plasmodium vivax serine/threonine protein kinase KIN, putative 0.0048 0.0105 0.0104
Loa Loa (eye worm) hypothetical protein 0.0014 0.0007 0.0034
Trypanosoma cruzi 5'-AMP-activated protein kinase subunit beta, putative 0.0111 0.0287 0.1492
Loa Loa (eye worm) thioredoxin reductase 0.0039 0.0078 0.0407
Trypanosoma cruzi 5'-AMP-activated protein kinase catalytic subunit alpha, putative 0.0048 0.0105 0.0545
Giardia lamblia Ubiquitin carboxyl-terminal hydrolase 4 0.0039 0.0078 0.047
Schistosoma mansoni vesicular amine transporter 0.0036 0.0069 0.0167
Plasmodium falciparum replication factor C subunit 1, putative 0.0021 0.0025 0.0024
Echinococcus granulosus acetylcholinesterase 0.0273 0.0757 0.1829
Mycobacterium ulcerans hypothetical protein 0.0021 0.0025 0.0021
Brugia malayi ATP-dependent DNA helicase, RecQ family protein 0.0021 0.0025 0.0129
Echinococcus multilocularis muscleblind protein 1 0.0611 0.174 0.1834
Trypanosoma brucei histone deacetylase 3 0.0672 0.1915 1
Echinococcus granulosus ATP dependent DNA helicase Q5 0.0021 0.0025 0.006
Echinococcus granulosus titin 0.0016 0.0012 0.003
Mycobacterium tuberculosis Conserved protein 0.0021 0.0025 0.0043
Brugia malayi histone deacetylase 3 (HD3) 0.0551 0.1565 0.817
Mycobacterium ulcerans hypothetical protein 0.0097 0.0247 0.0243
Trypanosoma brucei AIR9-like protein 0.0014 0.0006 0.0025
Loa Loa (eye worm) hypothetical protein 0.0072 0.0174 0.0908
Trichomonas vaginalis bromodomain-containing protein, putative 0.0044 0.0093 0.059
Echinococcus multilocularis hepatocyte nuclear factor 4 alpha 0.003 0.0053 0.0056
Schistosoma mansoni photoreceptor-specific nuclear receptor related 0.003 0.0053 0.0128
Loa Loa (eye worm) hypothetical protein 0.0097 0.0247 0.1289
Chlamydia trachomatis fructose-6-phosphate phosphotransferase 0.003 0.0053 0.0049
Brugia malayi hypothetical protein 0.0021 0.0025 0.0129
Trypanosoma brucei DNA polymerase eta, putative 0.0136 0.0359 0.1869
Plasmodium falciparum protein kinase 5 0.0048 0.0104 0.0103
Trichomonas vaginalis glucosylceramidase, putative 0.0254 0.0702 0.4473
Schistosoma mansoni 6-phosphofructokinase 0.0113 0.0292 0.0706
Brugia malayi Histone deacetylase family protein 0.0672 0.1915 1
Entamoeba histolytica long-chain-fatty-acid--CoA ligase, putative 0.0028 0.0048 0.03
Plasmodium falciparum importin beta, putative 0.003 0.0053 0.0052
Entamoeba histolytica hypothetical protein 0.0024 0.0036 0.0225
Echinococcus granulosus alkaline phosphatase intestinal gene 2 0.0169 0.0454 0.1098
Brugia malayi Patched family protein 0.0018 0.0018 0.0095
Toxoplasma gondii 6-phosphofructokinase 0.003 0.0053 0.0053
Mycobacterium ulcerans long-chain-fatty-acid--CoA ligase 0.0028 0.0048 0.0044
Trypanosoma cruzi apurinic/apyrimidinic endonuclease, putative 0.0019 0.0022 0.0108
Loa Loa (eye worm) hypothetical protein 0.0018 0.0018 0.0095
Echinococcus multilocularis protein patched 0.013 0.0341 0.036
Echinococcus granulosus 5'partial|histone lysine N methyltransferase SETDB2 0.003 0.0052 0.0125
Echinococcus multilocularis thioredoxin glutathione reductase 0.0039 0.0079 0.0084
Mycobacterium tuberculosis Possible fatty-acid-CoA ligase FadD1 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0028 0.0048 0.009
Entamoeba histolytica ubiquitin carboxyl-terminal hydrolase 5, putative 0.0015 0.001 0.0058
Schistosoma mansoni chromosome transmission fidelity factor 0.0021 0.0025 0.006
Mycobacterium ulcerans phenyloxazoline synthase MbtB 0.0028 0.0048 0.0044
Toxoplasma gondii Amylo-alpha-1,6-glucosidase 0.0014 0.0006 0.0005
Brugia malayi exodeoxyribonuclease III family protein 0.0019 0.0022 0.0113
Loa Loa (eye worm) hypothetical protein 0.0032 0.0059 0.0306
Echinococcus multilocularis diuretic hormone 44 receptor GPRdih2 0.0066 0.0155 0.0164
Echinococcus multilocularis roundabout 2 0.0022 0.003 0.0032
Brugia malayi hypothetical protein 0.0016 0.0012 0.006
Echinococcus granulosus DNA apurinic or apyrimidinic site lyase 0.0019 0.0022 0.0052
Loa Loa (eye worm) hypothetical protein 0.003 0.0053 0.0277
Echinococcus granulosus roundabout 2 0.0022 0.003 0.0073
Onchocerca volvulus 0.0058 0.0134 0.0968
Echinococcus multilocularis receptor type tyrosine protein phosphatase 0.0022 0.003 0.0032
Echinococcus granulosus family S9 non peptidase ue S09 family 0.0046 0.0099 0.0239
Onchocerca volvulus 0.0032 0.0059 0.0423
Giardia lamblia Flap structure-specific endonuclease 0.0054 0.0122 0.0754
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD3 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0069 0.0164 0.0327
Brugia malayi Immunoglobulin I-set domain containing protein 0.0022 0.003 0.0158
Echinococcus granulosus macrophage colony stimulating factor 1 receptor 0.0551 0.1563 0.3777
Brugia malayi jmjC domain containing protein 0.0061 0.0142 0.0742
Mycobacterium tuberculosis Probable conserved transmembrane alanine and leucine rich protein 0.0021 0.0025 0.0043
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0014 0.0007 0.0007
Loa Loa (eye worm) hypothetical protein 0.0611 0.174 0.9084
Brugia malayi nuclear receptor RXR 0.0014 0.0007 0.0034
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0286 0.0796 0.5077
Onchocerca volvulus 0.0018 0.0018 0.0131
Toxoplasma gondii ImpB/MucB/SamB family protein 0.006 0.014 0.0139
Echinococcus multilocularis nibrin 0.0021 0.0025 0.0026
Leishmania major DNA polymerase kappa, putative 0.0034 0.0063 0.0327
Brugia malayi acetyltransferase, GNAT family protein 0.015 0.0401 0.2094
Echinococcus granulosus hemicentin 1 0.0022 0.003 0.0073
Plasmodium vivax protein kinase Crk2 0.0048 0.0104 0.0103
Trypanosoma cruzi flap endonuclease-1 (FEN-1), putative 0.0054 0.0122 0.0632
Onchocerca volvulus Uncharacterized RING finger protein homolog 0.0012 0.0001 0.0007
Leishmania major acetyl-CoA synthetase, putative 0.0028 0.0048 0.0245
Brugia malayi putative serine/threonine kinase SADA gamma 0.0048 0.0105 0.0549
Chlamydia trachomatis phosphoshikimate 1-carboxyl vinyltransferase 0.0309 0.0861 0.0858
Brugia malayi Carboxylesterase family protein 0.0046 0.0099 0.0517
Loa Loa (eye worm) hypothetical protein 0.0021 0.0025 0.0129
Brugia malayi ancient conserved domain protein 4 0.0021 0.0025 0.0129
Wolbachia endosymbiont of Brugia malayi Mg2+/Co2+ transporter 0.0021 0.0025 0.0404
Loa Loa (eye worm) RecQ helicase 0.0021 0.0025 0.0129
Loa Loa (eye worm) hypothetical protein 0.0302 0.0841 0.4392
Entamoeba histolytica Activator 1 140 kDa subunit, putative 0.0021 0.0025 0.0152
Echinococcus granulosus histone deacetylase 7 0.0672 0.1915 0.4628
Schistosoma mansoni roundabout 0.0022 0.003 0.0073
Plasmodium falciparum lipid/sterol:H+ symporter 0.0018 0.0018 0.0017
Echinococcus multilocularis 5' AMP activated protein kinase subunit beta 1 0.0059 0.0138 0.0145
Mycobacterium ulcerans NAD-dependent DNA ligase LigA 0.0021 0.0025 0.002
Trichomonas vaginalis CAMK family protein kinase 0.0048 0.0105 0.0666
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0047 0.0102 0.0245
Giardia lamblia Aurora kinase 0.0169 0.0455 0.2887
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0013 0.0004 0.0017
Trypanosoma brucei hypothetical protein, conserved 0.0014 0.0006 0.0025
Echinococcus granulosus Protein patched homolog 1 0.013 0.0341 0.0824
Loa Loa (eye worm) hypothetical protein 0.0028 0.0048 0.025
Leishmania major histone deacetylase, putative 0.0551 0.1565 0.8169
Leishmania major histone deacetylase, putative 0.0672 0.1915 1
Echinococcus multilocularis receptor type tyrosine protein phosphatase 0.0022 0.003 0.0032
Trypanosoma cruzi acetyl-CoA synthetase, putative 0.0028 0.0048 0.0245
Echinococcus granulosus neuroglian 0.0022 0.003 0.0073
Schistosoma mansoni family C19 non-peptidase homologue (C19 family) 0.0015 0.001 0.0024
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0039 0.0078 0.0489
Trypanosoma brucei GTP-binding nuclear protein rtb2, putative 0.0022 0.003 0.015
Loa Loa (eye worm) nuclear hormone receptor family member nhr-1 0.003 0.0053 0.0277
Trichomonas vaginalis phosphofructokinase, putative 0.0113 0.0292 0.1859
Mycobacterium tuberculosis Conserved protein 0.0021 0.0025 0.0043
Onchocerca volvulus 0.0018 0.0018 0.0131
Brugia malayi Patched family protein 0.0018 0.0018 0.0095
Chlamydia trachomatis UDP-N-acetylglucosamine 1-carboxyvinyltransferase 0.0189 0.0513 0.0509
Schistosoma mansoni retinoid-x-receptor (RXR) 0.003 0.0053 0.0128
Echinococcus multilocularis cpg binding protein 0.0062 0.0144 0.0152
Brugia malayi Ubiquitin carboxyl-terminal hydrolase family protein 0.0039 0.0078 0.0405
Loa Loa (eye worm) hypothetical protein 0.0097 0.0247 0.1289
Trichomonas vaginalis phosphofructokinase, putative 0.003 0.0053 0.0335
Schistosoma mansoni hypothetical protein 0.0125 0.0328 0.0791
Trichomonas vaginalis histone deacetylase 1, 2 ,3, putative 0.0551 0.1565 0.9987
Entamoeba histolytica serine/threonine protein kinase 6, putative 0.0169 0.0455 0.2902
Trypanosoma cruzi hypothetical protein, conserved 0.0021 0.0025 0.0124
Trypanosoma cruzi mitochondrial DNA polymerase beta-PAK, putative 0.0147 0.0391 0.2039
Toxoplasma gondii UBA/TS-N domain-containing protein 0.0015 0.001 0.0009
Mycobacterium tuberculosis Probable 6-phosphofructokinase PfkA (phosphohexokinase) (phosphofructokinase) 0.0113 0.0292 0.0587
Schistosoma mansoni serine/threonine protein kinase 0.0048 0.0105 0.0254
Trichomonas vaginalis CAMK family protein kinase 0.0048 0.0105 0.0666
Echinococcus multilocularis 6 phosphofructokinase 0.0113 0.0292 0.0308
Loa Loa (eye worm) hypothetical protein 0.0021 0.0025 0.0129
Entamoeba histolytica protein kinase domain containing protein 0.0169 0.0455 0.2902
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.003 0.0053 0.0056
Toxoplasma gondii ubiquitin specific protease 39 isoform 2, putative 0.0015 0.001 0.0009
Loa Loa (eye worm) hypothetical protein 0.0406 0.1144 0.5971
Loa Loa (eye worm) hypothetical protein 0.003 0.0053 0.0277
Leishmania major serine/threonine protein kinase, putative,protein kinase, putative 0.0048 0.0105 0.0545
Brugia malayi nuclear hormone receptor family member nhr-6 0.0014 0.0007 0.0034
Schistosoma mansoni 3-dehydroquinate synthase 0.012 0.0314 0.0759
Entamoeba histolytica Flap nuclease, putative 0.0054 0.0122 0.0774
Toxoplasma gondii IMP dehydrogenas 0.0021 0.0025 0.0024
Entamoeba histolytica histone deacetylase, putative 0.0551 0.1565 1
Brugia malayi intracellular kinase 0.0051 0.0113 0.0589
Onchocerca volvulus 0.0028 0.0048 0.0345
Echinococcus multilocularis para nitrobenzyl esterase 0.0046 0.0099 0.0104
Trichomonas vaginalis importin beta-1, putative 0.0024 0.0036 0.0225
Brugia malayi Patched related family protein 4 0.0018 0.0018 0.0095
Trichomonas vaginalis conserved hypothetical protein 0.0013 0.0003 0.0016
Echinococcus granulosus tar DNA binding protein 0.0131 0.0344 0.0832
Leishmania major histone deacetylase, putative 0.0672 0.1915 1
Trypanosoma brucei DNA polymerase IV, putative 0.0163 0.0438 0.2282
Schistosoma mansoni tar DNA-binding protein 0.0131 0.0344 0.0832
Mycobacterium tuberculosis Possible fatty-acid-CoA ligase FadD10 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0028 0.0048 0.009
Loa Loa (eye worm) hypothetical protein 0.0018 0.0018 0.0095
Brugia malayi Patched related family protein 10 0.0018 0.0018 0.0095
Entamoeba histolytica cell division protein kinase 2, putative 0.0048 0.0104 0.0659
Loa Loa (eye worm) hypothetical protein 0.0611 0.174 0.9084
Toxoplasma gondii histone lysine acetyltransferase GCN5-A 0.0044 0.0093 0.0092
Trypanosoma cruzi trypanothione reductase, putative 0.0039 0.0078 0.0402
Wolbachia endosymbiont of Brugia malayi NAD-dependent DNA ligase, Lig 0.0021 0.0025 0.0402
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0013 0.0003 0.0016
Brugia malayi Peroxidasin 0.0022 0.003 0.0158
Mycobacterium ulcerans long-chain-fatty-acid--CoA ligase 0.0097 0.0247 0.0243
Schistosoma mansoni family S9 non-peptidase homologue (S09 family) 0.0046 0.0099 0.0239
Giardia lamblia GTP-binding nuclear protein RAN/TC4 0.0022 0.003 0.0163
Loa Loa (eye worm) hypothetical protein 0.0014 0.0007 0.0034
Trichomonas vaginalis AGC family protein kinase 0.0169 0.0455 0.2898
Schistosoma mansoni ubiquitin-specific peptidase 44 (C19 family) 0.0015 0.001 0.0024
Leishmania major hypothetical protein, conserved,leucine-rich repeat protein, putative 0.0014 0.0006 0.0025
Loa Loa (eye worm) hypothetical protein 0.0014 0.0007 0.0034
Loa Loa (eye worm) abnormal chemotaxis protein 14 0.013 0.0341 0.1781
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0013 0.0003 0.0016
Trichomonas vaginalis AGC family protein kinase 0.0169 0.0455 0.2898
Entamoeba histolytica hypothetical protein 0.0021 0.0025 0.0152
Schistosoma mansoni terminal deoxycytidyl transferase 0.0109 0.0282 0.0682
Loa Loa (eye worm) hypothetical protein 0.0018 0.0018 0.0095
Echinococcus multilocularis intestinal type alkaline phosphatase 1 0.0169 0.0454 0.0479
Echinococcus multilocularis peroxidasin 0.0022 0.003 0.0032
Echinococcus multilocularis dna polymerase kappa 0.0163 0.0438 0.0461
Schistosoma mansoni zinc finger protein 0.0014 0.0007 0.0016
Trichomonas vaginalis AGC family protein kinase 0.0169 0.0455 0.2898
Echinococcus granulosus alkaline phosphatase 0.0169 0.0454 0.1098
Loa Loa (eye worm) patched family protein 0.0018 0.0018 0.0095
Schistosoma mansoni family S9 non-peptidase homologue (S09 family) 0.0273 0.0757 0.1829
Plasmodium vivax acyl-CoA synthetase, putative 0.0073 0.0176 0.0175
Mycobacterium leprae POSSIBLE FATTY-ACID-CoA LIGASE FADD10 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) 0.0028 0.0048 0.0047
Loa Loa (eye worm) hypothetical protein 0.0073 0.0176 0.0917
Brugia malayi protein C24B5.3 0.0018 0.0018 0.0095
Schistosoma mansoni glutaminase 0.0552 0.1567 0.3786
Echinococcus multilocularis tyrosine protein kinase transmembrane receptor 0.0017 0.0013 0.0014
Toxoplasma gondii NEK kinase 0.0022 0.0028 0.0027
Trypanosoma cruzi protein kinase, putative 0.0017 0.0015 0.0075
Trypanosoma brucei SNF1-related protein kinases, putative 0.0048 0.0105 0.0545
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0015 0.001 0.0058
Echinococcus multilocularis ATP dependent DNA helicase Q5 0.0021 0.0025 0.0026
Brugia malayi Immunoglobulin I-set domain containing protein 0.0022 0.003 0.0158
Loa Loa (eye worm) histone deacetylase 1 0.0551 0.1565 0.817
Trypanosoma brucei histone deacetylase 4 0.0672 0.1915 1
Echinococcus granulosus AMPK beta subunit 0.0111 0.0287 0.0692
Entamoeba histolytica acyl-CoA synthetase, putative 0.0097 0.0247 0.1572
Giardia lamblia Endonuclease/Exonuclease/phosphatase 0.0019 0.0022 0.0112
Brugia malayi Steroid receptor seven-up type 2 0.003 0.0053 0.0277
Echinococcus multilocularis Immunoglobulin 0.0036 0.0069 0.0073
Brugia malayi Ubiquitin carboxyl-terminal hydrolase family protein 0.0015 0.001 0.0052
Trichomonas vaginalis histone deacetylase, putative 0.0551 0.1565 0.9987
Echinococcus granulosus hepatocyte nuclear factor 4 alpha 0.003 0.0053 0.0128
Echinococcus granulosus flap endonuclease 1 0.0054 0.0122 0.0295
Toxoplasma gondii patched family protein 0.0018 0.0018 0.0017
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0013 0.0004 0.0017
Onchocerca volvulus 0.0021 0.0025 0.0178
Echinococcus multilocularis alkaline phosphatase 0.0169 0.0454 0.0479
Plasmodium vivax importin-beta 2, putative 0.003 0.0053 0.0052
Brugia malayi nuclear hormone receptor family member odr-7 0.0014 0.0007 0.0034
Loa Loa (eye worm) hypothetical protein 0.0022 0.003 0.0158
Loa Loa (eye worm) hypothetical protein 0.0018 0.0018 0.0095
Plasmodium falciparum histone acetyltransferase GCN5 0.004 0.0083 0.0082
Entamoeba histolytica hypothetical protein 0.0189 0.0515 0.3284
Schistosoma mansoni serine/threonine protein kinase 0.0048 0.0105 0.0254
Echinococcus granulosus thyroid hormone receptor alpha 0.0014 0.0007 0.0016
Chlamydia trachomatis CBS domain-containing protein 0.0021 0.0025 0.0021
Entamoeba histolytica hypothetical protein 0.0039 0.0078 0.0492
Plasmodium vivax serine/threonine-protein kinase Nek1, putative 0.0022 0.0028 0.0027
Brugia malayi nuclear receptor NHR-67 0.0014 0.0007 0.0034
Echinococcus multilocularis acetylcholinesterase 0.0273 0.0757 0.0798
Loa Loa (eye worm) hypothetical protein 0.0044 0.0092 0.0478
Echinococcus granulosus ATP dependent DNA helicase Q1 0.0021 0.0025 0.006
Echinococcus multilocularis histone deacetylase 6 0.0672 0.1915 0.2019
Brugia malayi Carboxylesterase family protein 0.0273 0.0757 0.3953
Schistosoma mansoni ap endonuclease 0.0019 0.0022 0.0052
Schistosoma mansoni tar DNA-binding protein 0.0131 0.0344 0.0832
Brugia malayi Carboxylesterase family protein 0.0046 0.0099 0.0517
Onchocerca volvulus Glucosylceramidase homolog 0.0166 0.0448 0.3232
Trichomonas vaginalis Importin beta-1 subunit, putative 0.0024 0.0036 0.0225
Schistosoma mansoni septate junction protein 0.0022 0.003 0.0073
Loa Loa (eye worm) hypothetical protein 0.0061 0.0142 0.0739
Brugia malayi F/Y-rich N-terminus family protein 0.0019 0.002 0.0105
Leishmania major protein kinase, putative 0.0169 0.0455 0.2371
Loa Loa (eye worm) CMGC/GSK protein kinase 0.0051 0.0113 0.0589
Trichomonas vaginalis conserved hypothetical protein 0.0013 0.0003 0.0016
Trypanosoma brucei hypothetical protein, conserved 0.0034 0.0063 0.0327
Echinococcus multilocularis neuroglian 0.0048 0.0104 0.011
Brugia malayi Patched family protein 0.0018 0.0018 0.0095
Echinococcus multilocularis histone deacetylase 6 0.0684 0.1951 0.2057
Giardia lamblia 5-AMP-activated protein kinase, beta-1 subunit 0.0111 0.0287 0.1809
Trichomonas vaginalis antibiotic synthetase, putative 0.0028 0.0048 0.0299
Loa Loa (eye worm) hypothetical protein 0.0073 0.0176 0.0917
Schistosoma mansoni Tr4/Tr2 (homologue) 0.003 0.0053 0.0128
Brugia malayi nuclear receptor NHR-88 0.003 0.0053 0.0277
Mycobacterium tuberculosis PROBABLE FATTY-ACID-CoA LIGASE FADD18 (FRAGMENT) (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) 0.0025 0.0036 0.0066
Schistosoma mansoni gabp alpha 0.0071 0.0172 0.0415
Trichomonas vaginalis phosphofructokinase, putative 0.003 0.0053 0.0335
Plasmodium falciparum casein kinase II beta chain 0.0038 0.0075 0.0074
Trypanosoma cruzi acetyl-CoA synthetase, putative 0.0028 0.0048 0.0245
Entamoeba histolytica protein kinase, putative 0.0051 0.0113 0.0716
Loa Loa (eye worm) hypothetical protein 0.0014 0.0007 0.0034
Onchocerca volvulus 0.003 0.0053 0.0383
Plasmodium falciparum ubiquitin carboxyl-terminal hydrolase 13, putative 0.0015 0.001 0.0009
Onchocerca volvulus Alicorn homolog 0.0097 0.0246 0.1773
Toxoplasma gondii hypothetical protein 0.0014 0.0006 0.0005
Loa Loa (eye worm) acetylcholinesterase 1 0.0273 0.0757 0.3953
Echinococcus multilocularis Peptidase C19, ubiquitin carboxyl terminal hydrolase 2 0.0039 0.0078 0.0082
Schistosoma mansoni DNA helicase recq1 0.0021 0.0025 0.006
Echinococcus granulosus protein kinase shaggy 0.0051 0.0113 0.0273
Schistosoma mansoni jumonji/arid domain-containing protein 0.0064 0.0152 0.0366
Mycobacterium ulcerans cystathionine beta-synthase 0.0021 0.0025 0.0021
Schistosoma mansoni apoptosis regulator bax 0.0086 0.0214 0.0518
Trypanosoma brucei CMGC/DYRK protein kinase, putative 0.0189 0.0515 0.2683
Loa Loa (eye worm) carboxylesterase 0.0046 0.0099 0.0517
Leishmania major acetoin dehydrogenase e3 component-like protein 0.0013 0.0004 0.0017
Entamoeba histolytica exodeoxyribonuclease III, putative 0.0019 0.0022 0.0133
Echinococcus granulosus titin 0.0016 0.0012 0.003
Trypanosoma cruzi long-chain-fatty-acid-CoA ligase, putative 0.0028 0.0048 0.0245
Echinococcus multilocularis dihydrolipoamide dehydrogenase 0.0013 0.0004 0.0004
Brugia malayi 6-phosphofructokinase 0.0113 0.0292 0.1525
Plasmodium vivax chorismate synthase 0.3457 1 1
Trypanosoma brucei acetyl-CoA synthetase, putative 0.0028 0.0048 0.0245
Schistosoma mansoni septate junction protein 0.0022 0.003 0.0073
Trypanosoma cruzi Serine/threonine-protein kinase NEK11, putative 0.0022 0.0028 0.014
Plasmodium falciparum glutathione reductase 0.0039 0.0078 0.0077
Leishmania major long-chain-fatty-acid-CoA ligase, putative 0.0028 0.0048 0.0245
Trichomonas vaginalis DNA helicase recq, putative 0.0021 0.0025 0.0152
Schistosoma mansoni alzheimer's disease beta-amyloid related 0.0124 0.0325 0.0786
Trypanosoma brucei cdc2-related kinase 1 0.0048 0.0104 0.0538
Entamoeba histolytica Ran family GTPase 0.0022 0.003 0.0183
Trypanosoma brucei dihydrolipoyl dehydrogenase 0.0013 0.0004 0.0017
Leishmania major protein kinase ck2 regulatory subunit, putative 0.0038 0.0075 0.0388
Loa Loa (eye worm) histone deacetylase 3 0.0551 0.1565 0.817
Schistosoma mansoni hypothetical protein 0.0066 0.0155 0.0376
Brugia malayi Pre-SET motif family protein 0.0032 0.0059 0.0306
Trichomonas vaginalis chromosome transmission fidelity factor, putative 0.0021 0.0025 0.0152
Loa Loa (eye worm) nuclear Hormone Receptor family member 0.003 0.0053 0.0277
Entamoeba histolytica acetyltransferase, GNAT family 0.004 0.0083 0.0523
Echinococcus multilocularis BRCA1 associated protein 0.0012 0.0001 0.0001
Loa Loa (eye worm) hypothetical protein 0.0157 0.042 0.2191
Schistosoma mansoni nuclear hormone receptor superfamily protein-related 0.0014 0.0007 0.0016
Trypanosoma cruzi SNF1-related protein kinase regulatory subunit beta, putative 0.0111 0.0287 0.1492
Giardia lamblia Manganese-dependent inorganic pyrophosphatase, putative 0.0021 0.0025 0.0131
Brugia malayi Ubiquitin carboxyl-terminal hydrolase family protein 0.0015 0.001 0.0052
Leishmania major DNA polymerase kappa, putative,DNA polymerase IV, putative 0.0123 0.0321 0.1671
Brugia malayi Patched family protein 0.0018 0.0018 0.0095
Loa Loa (eye worm) immunoglobulin I-set domain-containing protein 0.0022 0.003 0.0158
Schistosoma mansoni jumonji/arid domain-containing protein 0.0064 0.0152 0.0366
Toxoplasma gondii exonuclease III APE 0.0019 0.0022 0.0021
Echinococcus granulosus histone deacetylase 6 0.0684 0.1951 0.4714
Plasmodium falciparum casein kinase II beta chain 0.0038 0.0075 0.0074
Trypanosoma cruzi DNA polymerase kappa, putative 0.0163 0.0438 0.2282
Plasmodium vivax replication factor C subunit 1, putative 0.0021 0.0025 0.0024
Trichomonas vaginalis replication factor C large subunit, putative 0.0021 0.0025 0.0152
Mycobacterium ulcerans 6-phosphofructokinase 0.0113 0.0292 0.0288
Trypanosoma cruzi DNA polymerase beta thumb, putative 0.0044 0.0092 0.0474
Giardia lamblia 5-AMP-activated protein kinase, gamma-1 subunit 0.0228 0.0627 0.3991
Trichomonas vaginalis glucosylceramidase, putative 0.0166 0.0448 0.2856
Echinococcus granulosus BC026374 protein S09 family 0.0046 0.0099 0.0239
Toxoplasma gondii ImpB/MucB/SamB family protein 0.0034 0.0063 0.0063
Trypanosoma brucei dihydrolipoamide dehydrogenase 0.0013 0.0004 0.0017
Schistosoma mansoni casein kinase II beta subunit 0.0038 0.0075 0.0182
Schistosoma mansoni protein kinase subunit beta 0.0059 0.0138 0.0332
Schistosoma mansoni acetyl-CoA synthetase 0.0028 0.0048 0.0116
Trichomonas vaginalis phosphofructokinase, putative 0.003 0.0053 0.0335
Mycobacterium leprae Chorismate synthase AroF (5-enolpyruvylshikimate-3-phosphate phospholyase). 0.1705 0.4913 1
Echinococcus granulosus H:Cl exchange transporter 4 0.0021 0.0025 0.006
Brugia malayi Nuclear hormone receptor family member nhr-3 0.003 0.0053 0.0277
Trypanosoma brucei aurora B kinase 0.0169 0.0455 0.2371
Trichomonas vaginalis glucosylceramidase, putative 0.0175 0.0474 0.3023
Trypanosoma cruzi histone deacetylase 1, putative 0.0551 0.1565 0.8169
Chlamydia trachomatis DNA ligase 0.0021 0.0025 0.002
Loa Loa (eye worm) hypothetical protein 0.0273 0.0757 0.3953
Trichomonas vaginalis conserved hypothetical protein 0.013 0.0341 0.2172
Leishmania major hypothetical protein, conserved 0.0051 0.0114 0.0589
Loa Loa (eye worm) GTP-binding regulatory protein Gs alpha-S chain 0.0047 0.0102 0.053
Trichomonas vaginalis cat eye syndrome critical region protein 2, cscr2, putative 0.0044 0.0093 0.059
Loa Loa (eye worm) loechrig isoform VII 0.0228 0.0627 0.3274
Trypanosoma brucei DNA polymerase kappa, putative 0.0123 0.0321 0.1671
Loa Loa (eye worm) hypothetical protein 0.0261 0.0723 0.3775
Loa Loa (eye worm) jmjC domain-containing protein 0.0016 0.0012 0.0064
Plasmodium vivax DNA repair protein REV1, putative 0.0034 0.0063 0.0063
Schistosoma mansoni serine/threonine protein kinase 0.0048 0.0105 0.0254
Trichomonas vaginalis mercuric reductase, putative 0.0013 0.0004 0.0021
Treponema pallidum fructose-bisphosphate aldolase 0.0286 0.0796 1
Echinococcus multilocularis histone deacetylase 0.0672 0.1915 0.2019
Loa Loa (eye worm) hypothetical protein 0.003 0.0053 0.0277
Trypanosoma cruzi AMP-activated protein kinase, gamma regulatory subunit 0.0021 0.0025 0.0124
Trypanosoma brucei histone deacetylase 2 0.0278 0.0773 0.4031
Schistosoma mansoni AMP-activated protein kinase gamma regulatory subunit 0.0021 0.0025 0.006
Mycobacterium ulcerans chorismate synthase 0.3457 1 1
Trypanosoma brucei Casein kinase II subunit beta, putative 0.0038 0.0075 0.0388
Toxoplasma gondii casein kinase ii regulatory subunit protein 0.0038 0.0075 0.0074
Echinococcus multilocularis Transcription factor, JmjC domain containing protein 0.0061 0.0142 0.015
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0013 0.0003 0.0016
Trichomonas vaginalis conserved hypothetical protein 0.0021 0.0025 0.0152
Loa Loa (eye worm) hypothetical protein 0.003 0.0053 0.0277
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD35 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0069 0.0164 0.0327
Loa Loa (eye worm) IMP dehydrogenase 1 0.0021 0.0025 0.0129
Brugia malayi RNA binding protein 0.0131 0.0344 0.1797
Brugia malayi GTP-binding regulatory protein Gs alpha-S chain, putative 0.0047 0.0102 0.053
Brugia malayi ImpB/MucB/SamB family protein 0.0136 0.0359 0.1873
Schistosoma mansoni cpg binding protein 0.0062 0.0144 0.0348
Loa Loa (eye worm) hypothetical protein 0.0207 0.0567 0.2959
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0125 0.0327 0.0791
Loa Loa (eye worm) AMP-binding enzyme family protein 0.0028 0.0048 0.025
Brugia malayi nuclear receptor NHR-88 0.0014 0.0007 0.0034
Loa Loa (eye worm) exodeoxyribonuclease III family protein 0.0019 0.0022 0.0113
Schistosoma mansoni neurotracting/lsamp/neurotrimin/obcam related cell adhesion molecule 0.0022 0.003 0.0073
Loa Loa (eye worm) hypothetical protein 0.0073 0.0176 0.0917
Schistosoma mansoni ubiquitin-specific peptidase 8 (C19 family) 0.0039 0.0078 0.0187
Schistosoma mansoni ran 0.0022 0.003 0.0072
Schistosoma mansoni niemann-pick C1 (NPC1) 0.0307 0.0855 0.2065
Echinococcus multilocularis histone lysine N methyltransferase SETMAR 0.0032 0.0059 0.0062
Trypanosoma brucei DNA polymerase kappa, putative 0.0163 0.0438 0.2282
Loa Loa (eye worm) hypothetical protein 0.0044 0.0093 0.0484
Chlamydia trachomatis fructose-6-phosphate phosphotransferase 0.003 0.0053 0.0049
Brugia malayi Nuclear hormone receptor E75 0.0014 0.0007 0.0034
Schistosoma mansoni ubiquitin-specific peptidase 5 (C19 family) 0.0015 0.001 0.0024
Mycobacterium tuberculosis Probable soluble pyridine nucleotide transhydrogenase SthA (STH) (NAD(P)(+) transhydrogenase [B-specific]) (nicotinamide nucleot 0.0013 0.0004 0.0001
Entamoeba histolytica fructose-1,6-bisphosphate aldolase, putative 0.0286 0.0796 0.5084
Brugia malayi Patched family protein 0.0018 0.0018 0.0095
Mycobacterium tuberculosis Probable conserved transmembrane protein 0.0021 0.0025 0.0043
Brugia malayi jmjC domain containing protein 0.0016 0.0012 0.0064
Loa Loa (eye worm) fli-1 protein 0.0216 0.0592 0.3091
Brugia malayi AMP-binding enzyme family protein 0.0097 0.0247 0.1289
Echinococcus multilocularis serine:threonine protein kinase 12 B 0.0169 0.0455 0.0479
Brugia malayi hypothetical protein 0.0125 0.0328 0.1712
Toxoplasma gondii propionate-CoA ligase 0.0028 0.0048 0.0047
Mycobacterium leprae PROBABLE NADH DEHYDROGENASE NDH 0.0089 0.0222 0.0405
Loa Loa (eye worm) hypothetical protein 0.0088 0.0219 0.1144
Trypanosoma brucei ATP-dependent 6-phosphofructokinase, glycosomal 0.0113 0.0292 0.1521
Brugia malayi ecdysone receptor 0.0014 0.0007 0.0034
Trichomonas vaginalis CAMK family protein kinase 0.0048 0.0105 0.0666
Echinococcus granulosus aurora kinase A 0.0169 0.0455 0.1099
Entamoeba histolytica casein kinase II regulatory subunit family protein 0.0038 0.0075 0.0475
Mycobacterium ulcerans fatty-acid-CoA ligase 0.0073 0.0176 0.0171
Entamoeba histolytica hypothetical protein 0.0039 0.0078 0.0492
Brugia malayi cell division control protein 2 homolog 0.0048 0.0104 0.0543
Mycobacterium ulcerans peptide synthetase Nrp (peptide synthase) 0.0028 0.0048 0.0044
Echinococcus granulosus FTZ F1 nuclear receptor protein 0.003 0.0053 0.0128
Trypanosoma cruzi DNA polymerase kappa, putative 0.0163 0.0438 0.2282
Trypanosoma cruzi mitochondrial DNA polymerase beta-PAK, putative 0.0044 0.0092 0.0474
Echinococcus multilocularis histone lysine methyltransferase setb histone lysine methyltransferase eggless 0.0032 0.0059 0.0062
Brugia malayi Immunoglobulin I-set domain containing protein 0.0022 0.003 0.0158
Trypanosoma brucei DNA polymerase kappa, putative 0.0163 0.0438 0.2282
Trypanosoma cruzi BRCA1 C Terminus (BRCT) domain containing protein, putative 0.0021 0.0025 0.0124
Schistosoma mansoni nephrin 0.0048 0.0104 0.0251
Echinococcus multilocularis H(+):Cl() exchange transporter 3 0.0021 0.0025 0.0026
Loa Loa (eye worm) hypothetical protein 0.0144 0.0383 0.2001
Chlamydia trachomatis acylglycerophosphoethanolamine acyltransferase 0.0073 0.0176 0.0171
Brugia malayi Bloom's syndrome protein homolog 0.0021 0.0025 0.0129
Trypanosoma cruzi DNA polymerase kappa, putative 0.0163 0.0438 0.2282
Schistosoma mansoni protein kinase 0.0169 0.0455 0.1099
Chlamydia trachomatis GutQ/KpsF family sugar-phosphate isomerase 0.0021 0.0025 0.0021
Plasmodium falciparum dihydrolipoyl dehydrogenase, apicoplast 0.0013 0.0004 0.0003
Echinococcus granulosus acetyl coenzyme A synthetase cytoplasmic 0.0028 0.0048 0.0116
Loa Loa (eye worm) hypothetical protein 0.0018 0.0018 0.0095
Echinococcus granulosus inosine 5' monophosphate dehydrogenase 2 0.0021 0.0025 0.006
Brugia malayi Immunoglobulin I-set domain containing protein 0.0022 0.003 0.0158
Loa Loa (eye worm) hypothetical protein 0.0022 0.003 0.0158
Echinococcus multilocularis GA binding protein alpha chain 0.0071 0.0172 0.0181
Brugia malayi RNA, U transporter 1 0.0086 0.0214 0.1119
Trichomonas vaginalis glucosylceramidase, putative 0.0254 0.0702 0.4473
Echinococcus multilocularis snurportin 1 0.0322 0.0901 0.095
Mycobacterium tuberculosis Probable dehydrogenase 0.0089 0.0222 0.0446
Trypanosoma brucei dihydrolipoamide dehydrogenase, point mutation 0.0013 0.0004 0.0017
Brugia malayi Calcitonin receptor-like protein seb-1 0.0207 0.0567 0.2959
Loa Loa (eye worm) hypothetical protein 0.0046 0.0099 0.0517
Loa Loa (eye worm) hypothetical protein 0.0018 0.0018 0.0095
Plasmodium falciparum acyl-CoA synthetase 0.0073 0.0176 0.0175
Trichomonas vaginalis casein kinase II beta chain, putative 0.0038 0.0075 0.0474
Schistosoma mansoni family S9 non-peptidase homologue (S09 family) 0.0046 0.0099 0.0239
Trichomonas vaginalis glucosylceramidase, putative 0.0175 0.0474 0.3023
Onchocerca volvulus 0.0028 0.0048 0.0345
Trichomonas vaginalis casein kinase II beta chain, putative 0.0038 0.0075 0.0474
Plasmodium falciparum DNA repair protein REV1, putative 0.0034 0.0063 0.0063
Schistosoma mansoni RAR-like nuclear receptor 0.003 0.0053 0.0128
Trypanosoma cruzi NIMA-related kinase, putative 0.0022 0.0028 0.014
Trypanosoma cruzi DNA polymerase eta, putative 0.0136 0.0359 0.1869
Loa Loa (eye worm) CMGC/CDK/CDC2 protein kinase 0.0048 0.0104 0.0543
Loa Loa (eye worm) hypothetical protein 0.0052 0.0115 0.0603
Giardia lamblia Sgs1 DNA helicase, putative 0.0021 0.0025 0.0132
Schistosoma mansoni family S9 non-peptidase homologue (S09 family) 0.0046 0.0099 0.0239
Trichomonas vaginalis phosphofructokinase, putative 0.003 0.0053 0.0335
Trypanosoma cruzi inosine-5'-monophosphate dehydrogenase, putative 0.0021 0.0025 0.0124
Loa Loa (eye worm) nuclear hormone receptor family member nhr-49 0.003 0.0053 0.0277
Loa Loa (eye worm) glutathione reductase 0.0039 0.0078 0.0407
Giardia lamblia Histone acetyltransferase GCN5 0.004 0.0083 0.0503
Mycobacterium leprae POSSIBLE O-SUCCINYLBENZOIC ACID--CoA LIGASE MENE (OSB-CoA SYNTHETASE) (O-SUCCINYLBENZOATE-CoA SYNTHASE) 0.0028 0.0048 0.0047
Brugia malayi Csnk2b protein 0.0038 0.0075 0.0392
Brugia malayi Nuclear hormone receptor family member nhr-40 0.003 0.0053 0.0277
Wolbachia endosymbiont of Brugia malayi hemolysin 0.0021 0.0025 0.0404
Trypanosoma brucei DNA polymerase IV, putative 0.0163 0.0438 0.2282
Trypanosoma cruzi dihydrolipoyl dehydrogenase, putative 0.0013 0.0004 0.0017
Loa Loa (eye worm) hypothetical protein 0.0021 0.0025 0.0129
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0047 0.0102 0.0107
Mycobacterium leprae Probable fructose bisphosphate aldolase Fba 0.014 0.0371 0.0709
Schistosoma mansoni serine/threonine protein kinase 0.0048 0.0104 0.0251
Echinococcus multilocularis EGFP:Bcl2 fusion protein 0.0086 0.0214 0.0226
Mycobacterium ulcerans long-chain-fatty-acid-CoA ligase 0.0097 0.0247 0.0243
Trypanosoma brucei DNA polymerase kappa, putative 0.0163 0.0438 0.2282
Trichomonas vaginalis casein kinase II beta chain, putative 0.0038 0.0075 0.0474
Echinococcus granulosus nuclear receptor 2DBD gamma 0.003 0.0053 0.0128
Trichomonas vaginalis DNA polymerase eta, putative 0.0163 0.0438 0.2789
Echinococcus multilocularis receptor type tyrosine protein phosphatase F 0.0022 0.003 0.0032
Trypanosoma brucei BRCA1 C Terminus (BRCT) domain containing protein, putative 0.0021 0.0025 0.0124
Plasmodium falciparum glutathione reductase 0.0013 0.0004 0.0003
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0013 0.0003 0.0016
Loa Loa (eye worm) transcription factor SMAD2 0.0124 0.0324 0.1693
Echinococcus multilocularis ubiquitin carboxyl terminal hydrolase 5 0.0015 0.001 0.0011
Echinococcus granulosus lachesin 0.0022 0.003 0.0073
Schistosoma mansoni topbp1 0.0021 0.0025 0.006
Trypanosoma cruzi DNA damage repair protein, putative 0.0034 0.0063 0.0327
Loa Loa (eye worm) histone deacetylase 0.0672 0.1915 1
Plasmodium falciparum JmjC domain-containing protein, putative 0.0016 0.0012 0.0011
Echinococcus multilocularis carboxylesterase 5A 0.0273 0.0757 0.0798
Mycobacterium tuberculosis Probable oxidoreductase 0.0099 0.0251 0.0504
Trichomonas vaginalis histone deacetylase, putative 0.0551 0.1565 0.9987
Onchocerca volvulus Protein ultraspiracle homolog 0.003 0.0053 0.0383
Schistosoma mansoni hypothetical protein 0.0142 0.0376 0.0909
Onchocerca volvulus Rap guanine nucleotide exchange factor 1 homolog 0.0185 0.0503 0.3631
Schistosoma mansoni bcl-2 homologous antagonist/killer (bak) 0.0086 0.0214 0.0518
Trypanosoma brucei importin beta-1 subunit, putative 0.003 0.0053 0.0271
Toxoplasma gondii cell-cycle-associated protein kinase GSK, putative 0.0051 0.0113 0.0112
Mycobacterium tuberculosis Conserved hypothetical protein 0.0163 0.044 0.0888
Trypanosoma brucei DNA polymerase kappa, putative 0.0089 0.0222 0.1157
Trypanosoma brucei Serine/threonine-protein kinase NEK11, putative 0.0022 0.0028 0.014
Mycobacterium tuberculosis Fatty-acid-AMP ligase FadD30 (fatty-acid-AMP synthetase) (fatty-acid-AMP synthase) 0.0073 0.0176 0.035
Brugia malayi hypothetical protein 0.0157 0.042 0.2191
Echinococcus multilocularis COUP TF:Svp nuclear hormone receptor 0.003 0.0053 0.0056
Trichomonas vaginalis CAMK family protein kinase 0.0048 0.0105 0.0666
Trypanosoma brucei 5'-AMP-activated protein kinase subunit beta 0.0111 0.0287 0.1492
Loa Loa (eye worm) CAMK/CAMKL/AMPK protein kinase 0.0236 0.065 0.3395
Echinococcus multilocularis nuclear receptor subfamily 1 group D 0.0016 0.0012 0.0012
Schistosoma mansoni microtubule-associated protein tau 0.1438 0.4139 1
Chlamydia trachomatis dehyroquinate synthase 0.012 0.0314 0.031
Brugia malayi Importin beta-1 subunit 0.003 0.0053 0.0275
Loa Loa (eye worm) hypothetical protein 0.0036 0.0069 0.0361
Echinococcus multilocularis histone lysine N methyltransferase MLL3 0.0019 0.0021 0.0022
Echinococcus granulosus ubiquitin carboxyl terminal hydrolase 8 0.0039 0.0078 0.0187
Brugia malayi CBS domain containing protein 0.0021 0.0025 0.0129
Echinococcus granulosus cyclin dependent kinase 5 activator 1 0.0261 0.0723 0.1747
Loa Loa (eye worm) hypothetical protein 0.0046 0.0099 0.0517
Trypanosoma cruzi PAB1-binding protein , putative 0.0051 0.0114 0.0589
Schistosoma mansoni thyroid hormone receptor 0.003 0.0053 0.0128
Brugia malayi BRCA1-associated protein 2 containing protein 0.0012 0.0001 0.0005
Trypanosoma cruzi importin beta-1 subunit, putative 0.0024 0.0036 0.0184
Trichomonas vaginalis CMGC family protein kinase 0.0051 0.0113 0.0715
Onchocerca volvulus 0.0018 0.0018 0.0131
Brugia malayi nuclear receptor RXR 0.0016 0.0012 0.006
Echinococcus multilocularis atpase aaa+ type core atpase aaa type core 0.328 0.9488 1
Echinococcus multilocularis muscleblind protein 0.0611 0.174 0.1834
Schistosoma mansoni glycogen synthase kinase 3-related (gsk3) (cmgc group III) 0.0051 0.0113 0.0273
Brugia malayi hypothetical protein 0.0039 0.0078 0.0406
Mycobacterium leprae PROBABLE 6-PHOSPHOFRUCTOKINASE PFKA (PHOSPHOHEXOKINASE) (PHOSPHOFRUCTOKINASE) 0.0113 0.0292 0.0547
Trypanosoma cruzi cdc2-related kinase 3 0.0048 0.0104 0.0538
Loa Loa (eye worm) TK/ROR protein kinase 0.0017 0.0013 0.007
Loa Loa (eye worm) CAMK/CAMKL/BRSK protein kinase 0.0048 0.0105 0.0549
Brugia malayi tailless protein 0.0014 0.0007 0.0034
Brugia malayi 6-phosphofructokinase 0.0113 0.0292 0.1526
Trypanosoma brucei DNA damage repair protein, putative 0.0034 0.0063 0.0327
Trypanosoma brucei DNA polymerase kappa, putative 0.0163 0.0438 0.2282
Treponema pallidum hemolysin (tlyC) 0.0021 0.0025 0.0259
Loa Loa (eye worm) hypothetical protein 0.0018 0.0018 0.0095
Loa Loa (eye worm) hypothetical protein 0.0073 0.0176 0.0917
Leishmania major ubiquitin hydrolase, putative,cysteine peptidase, Clan CA, family C19, putative 0.0039 0.0078 0.04
Plasmodium vivax glutathione reductase, putative 0.0039 0.0078 0.0077
Trypanosoma brucei trypanothione reductase 0.0039 0.0078 0.0402
Brugia malayi Fli-1 protein 0.0216 0.0592 0.3091
Echinococcus granulosus thioredoxin glutathione reductase 0.0039 0.0079 0.0192
Brugia malayi Immunoglobulin I-set domain containing protein 0.0017 0.0013 0.007
Loa Loa (eye worm) hypothetical protein 0.0125 0.0328 0.1712
Trichomonas vaginalis conserved hypothetical protein 0.0039 0.0078 0.0489
Schistosoma mansoni histone deacetylase hda2 0.0278 0.0773 0.1867
Schistosoma mansoni AMP-activated protein kinase gamma regulatory subunit 0.0021 0.0025 0.006
Schistosoma mansoni hypothetical protein 0.0086 0.0214 0.0518
Schistosoma mansoni nuclear receptor 2DBD-gamma 0.003 0.0053 0.0128
Plasmodium falciparum AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.0019 0.0022 0.0021
Echinococcus granulosus jumonji domain containing 1A 0.0016 0.0012 0.003
Echinococcus granulosus AMP activated protein kinase gamma regulatory 0.0021 0.0025 0.006
Onchocerca volvulus 0.0434 0.1224 0.8829
Giardia lamblia Manganese-dependent inorganic pyrophosphatase, putative 0.0021 0.0025 0.0131
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0286 0.0796 0.5077
Trypanosoma cruzi DNA polymerase beta thumb, putative 0.0044 0.0092 0.0474
Trichomonas vaginalis glucosylceramidase, putative 0.0254 0.0702 0.4473
Onchocerca volvulus 0.0046 0.0099 0.0713
Schistosoma mansoni hypothetical protein 0.0125 0.0328 0.0791
Plasmodium falciparum U4/U6.U5 tri-snRNP-associated protein 2, putative 0.0015 0.001 0.0009
Trichomonas vaginalis phosphofructokinase, putative 0.003 0.0053 0.0335
Trichomonas vaginalis CMGC family protein kinase 0.0048 0.0104 0.0658
Loa Loa (eye worm) flap endonuclease-1 0.0054 0.0122 0.0637
Onchocerca volvulus 0.0018 0.0018 0.0131
Schistosoma mansoni neuroligin 3 (S09 family) 0.0046 0.0099 0.0239
Onchocerca volvulus 0.0016 0.0012 0.009
Brugia malayi AMP-binding enzyme family protein 0.0028 0.0048 0.025
Plasmodium falciparum thioredoxin reductase 0.0013 0.0004 0.0003
Schistosoma mansoni tyrosine kinase 0.0027 0.0044 0.0105
Trypanosoma brucei JmjC domain, hydroxylase, putative 0.0016 0.0012 0.0059
Onchocerca volvulus Protein patched homolog 0.0018 0.0018 0.0131
Echinococcus granulosus bloom syndrome protein 0.0021 0.0025 0.006
Schistosoma mansoni histone deacetylase 0.0551 0.1565 0.3781
Echinococcus granulosus Transcription factor JmjC domain containing protein 0.0061 0.0142 0.0343
Brugia malayi CXXC zinc finger family protein 0.0058 0.0134 0.0701
Mycobacterium leprae DIHYDROLIPOAMIDE DEHYDROGENASE LPD (LIPOAMIDE REDUCTASE (NADH)) (LIPOYL DEHYDROGENASE) (DIHYDROLIPOYL DEHYDROGENASE) (DIAPHORASE 0.0099 0.0251 0.0463
Trichomonas vaginalis RNA polymerase II ctd phosphatase, putative 0.0021 0.0025 0.0152
Mycobacterium ulcerans acyl-CoA synthetase 0.0028 0.0048 0.0044
Wolbachia endosymbiont of Brugia malayi Mg/Co/Ni transporter MgtE 0.0021 0.0025 0.0404
Schistosoma mansoni retinoic acid receptor RXR 0.003 0.0053 0.0128
Toxoplasma gondii patched family protein 0.0018 0.0018 0.0017
Leishmania major DNA damage repair protein, putative 0.0034 0.0063 0.0327
Brugia malayi Patched family protein 0.0018 0.0018 0.0095
Loa Loa (eye worm) hypothetical protein 0.0028 0.0048 0.025
Schistosoma mansoni jumonji domain containing protein 0.0016 0.0012 0.003
Schistosoma mansoni brca1-associated protein (brap2) 0.0012 0.0001 0.0002
Mycobacterium tuberculosis Probable nitrite reductase [NAD(P)H] large subunit [FAD flavoprotein] NirB 0.0089 0.0222 0.0446
Onchocerca volvulus Casein kinase II subunit beta homolog 0.0038 0.0075 0.0542
Toxoplasma gondii NEK kinase 0.0022 0.0028 0.0027
Loa Loa (eye worm) hypothetical protein 0.003 0.0053 0.0277
Trichomonas vaginalis casein kinase II beta chain, putative 0.0038 0.0075 0.0474
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD5 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0069 0.0164 0.0327
Echinococcus multilocularis GPCR, family 2 0.0066 0.0155 0.0164
Trypanosoma cruzi cdc2-related kinase 1 0.0048 0.0104 0.0538
Giardia lamblia Pyrophosphate-fructose 6-phosphate 1-phosphotransferase alpha subunit 0.003 0.0053 0.0316
Plasmodium falciparum GTP-binding nuclear protein RAN/TC4 0.0022 0.003 0.0029
Schistosoma mansoni histone deacetylase 0.0551 0.1565 0.3781
Brugia malayi hypothetical protein 0.0046 0.0099 0.0517
Onchocerca volvulus 0.0157 0.042 0.3027
Trichomonas vaginalis glucosylceramidase, putative 0.0254 0.0702 0.4473
Echinococcus multilocularis tar DNA binding protein 0.0131 0.0344 0.0363
Mycobacterium tuberculosis 3-phosphoshikimate 1-carboxyvinyltransferase AroA (5-enolpyruvylshikimate-3-phosphate synthase) (EPSP synthase) (EPSPS) 0.012 0.0314 0.0632
Mycobacterium tuberculosis Probable medium chain fatty-acid-CoA ligase FadD14 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0028 0.0048 0.009
Trypanosoma cruzi CMGC/DYRK protein kinase, putative 0.0189 0.0515 0.2683
Toxoplasma gondii ATPase, AAA family protein 0.0021 0.0025 0.0024
Brugia malayi Latrophilin receptor protein 2 0.0066 0.0155 0.0812
Entamoeba histolytica casein kinase II regulatory subunit family protein 0.0038 0.0075 0.0475
Loa Loa (eye worm) hypothetical protein 0.0434 0.1224 0.6392
Echinococcus granulosus FTZ F1 alpha 0.003 0.0053 0.0128
Loa Loa (eye worm) nuclear hormone receptor family member nhr-40 0.003 0.0053 0.0277
Schistosoma mansoni cpg binding protein 0.0058 0.0134 0.0324
Plasmodium falciparum NIMA related kinase 4 0.0022 0.0028 0.0027
Loa Loa (eye worm) hypothetical protein 0.0021 0.0025 0.0129
Loa Loa (eye worm) ubiquitin carboxyl-terminal hydrolase 0.0015 0.001 0.0052
Trypanosoma brucei DNA polymerase kappa, putative 0.0088 0.0219 0.114
Loa Loa (eye worm) glutaminase 0.0552 0.1567 0.8181
Loa Loa (eye worm) CXXC zinc finger family protein 0.0058 0.0134 0.0701
Brugia malayi MH2 domain containing protein 0.0124 0.0324 0.1693
Toxoplasma gondii AMP-binding enzyme domain-containing protein 0.0028 0.0048 0.0047
Brugia malayi EST embl|AI107989|AI107989 comes from the 3' UTR, putative 0.0236 0.065 0.3395
Onchocerca volvulus Steroid hormone receptor family member cnr14 homolog 0.003 0.0053 0.0383
Loa Loa (eye worm) ubiquitin carboxyl-terminal hydrolase 0.0015 0.001 0.0052
Mycobacterium tuberculosis Conserved hypothetical protein 0.0109 0.0282 0.0567
Loa Loa (eye worm) carboxylesterase 0.0273 0.0757 0.3953
Brugia malayi Patched related family protein 12 0.0018 0.0018 0.0095
Brugia malayi AMP-binding enzyme family protein 0.0097 0.0247 0.1289
Mycobacterium ulcerans acyl-CoA synthetase 0.0028 0.0048 0.0044
Echinococcus granulosus ecdysone induced protein 78C 0.003 0.0053 0.0128
Schistosoma mansoni hypothetical protein 0.0066 0.0155 0.0376
Trypanosoma brucei DNA polymerase kappa, putative 0.0088 0.0219 0.114
Trichomonas vaginalis CAMK family protein kinase 0.0022 0.0028 0.0171
Brugia malayi nuclear receptor subfamily 1, group D, member 1, putative 0.0014 0.0007 0.0034
Echinococcus granulosus tumor protein p63 0.0354 0.0992 0.2397
Trypanosoma cruzi Serine/threonine-protein kinase NEK11, putative 0.0022 0.0028 0.014
Echinococcus granulosus histone lysine N methyltransferase MLL3 0.0016 0.001 0.0025
Toxoplasma gondii NADPH-glutathione reductase 0.0013 0.0004 0.0003
Brugia malayi hypothetical protein 0.0021 0.0025 0.0129
Loa Loa (eye worm) hypothetical protein 0.0036 0.0069 0.0361
Brugia malayi serine/threonine-protein kinase 6 0.0169 0.0455 0.2374
Schistosoma mansoni hypothetical protein 0.0086 0.0214 0.0518
Trypanosoma cruzi cdc2-related kinase 1 0.0048 0.0104 0.0538
Echinococcus multilocularis cyclin dependent kinase 0.0048 0.0104 0.011
Brugia malayi Thioredoxin reductase 0.0039 0.0078 0.0407
Loa Loa (eye worm) hypothetical protein 0.0022 0.003 0.0158
Leishmania major flap endonuclease-1 (FEN-1), putative 0.0054 0.0122 0.0632
Schistosoma mansoni nuclear receptor nhr-48 0.0014 0.0007 0.0016
Plasmodium vivax GTP-binding nuclear protein RAN/TC4, putative 0.0022 0.003 0.0029
Toxoplasma gondii histone lysine demethylase JMJD6a 0.0016 0.0012 0.0011
Brugia malayi AMP-binding enzyme family protein 0.0097 0.0247 0.1289
Loa Loa (eye worm) nuclear hormone receptor 0.0014 0.0007 0.0034
Echinococcus granulosus serine:threonine protein kinase 12 B 0.0169 0.0455 0.1099
Giardia lamblia Kinase, CAMK CAMKL 0.0048 0.0105 0.0647
Schistosoma mansoni protein kinase subunit beta 0.0111 0.0287 0.0692
Onchocerca volvulus 0.0021 0.0025 0.0178
Giardia lamblia DINP protein human, muc B family 0.0123 0.0321 0.2028
Leishmania major hypothetical protein, conserved 0.0111 0.0287 0.1492
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0047 0.0102 0.0245
Brugia malayi Carboxylesterase family protein 0.0046 0.0099 0.0517
Trichomonas vaginalis casein kinase II beta chain, putative 0.0038 0.0075 0.0474
Loa Loa (eye worm) hypothetical protein 0.0014 0.0007 0.0034
Loa Loa (eye worm) hypothetical protein 0.0159 0.0426 0.2223
Schistosoma mansoni serine/threonine protein kinase 0.0048 0.0104 0.0251
Trichomonas vaginalis CAMK family protein kinase 0.0048 0.0105 0.0666
Schistosoma mansoni nuclear hormone receptor nor-1/nor-2 0.003 0.0053 0.0128
Plasmodium vivax casein kinase II beta chain, putative 0.0038 0.0075 0.0074
Brugia malayi hypothetical protein 0.0018 0.0018 0.0095
Loa Loa (eye worm) oxidoreductase 0.0028 0.0048 0.025
Mycobacterium ulcerans acetyl-CoA synthetase 0.0028 0.0048 0.0044
Loa Loa (eye worm) pre-SET domain-containing protein family protein 0.0217 0.0595 0.3106
Mycobacterium tuberculosis NADPH-dependent mycothiol reductase Mtr 0.0039 0.0078 0.0151
Mycobacterium tuberculosis Phenyloxazoline synthase MbtB (phenyloxazoline synthetase) 0.0028 0.0048 0.009
Trypanosoma cruzi long-chain-fatty-acid-CoA ligase, putative 0.0028 0.0048 0.0245
Toxoplasma gondii histone deacetylase HDAC5 0.0278 0.0773 0.0772
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0047 0.0102 0.0245
Echinococcus granulosus retinoic acid receptor rxr beta a 0.003 0.0053 0.0128
Trypanosoma cruzi FHA domain containing protein, putative 0.0021 0.0025 0.0124
Mycobacterium ulcerans fructose-bisphosphate aldolase 0.014 0.0371 0.0367
Loa Loa (eye worm) hypothetical protein 0.0058 0.0134 0.0701
Toxoplasma gondii patched family protein 0.0018 0.0018 0.0017
Brugia malayi RNA recognition motif domain containing protein 0.0131 0.0344 0.1797
Brugia malayi Immunoglobulin I-set domain containing protein 0.0022 0.003 0.0158
Mycobacterium ulcerans exodeoxyribonuclease III protein XthA 0.0019 0.0022 0.0017
Echinococcus multilocularis acetyl coenzyme A synthetase, cytoplasmic 0.0028 0.0048 0.005
Schistosoma mansoni hypothetical protein 0.0125 0.0328 0.0791
Echinococcus multilocularis hemicentin 1 0.0022 0.003 0.0032
Schistosoma mansoni FTZ-F1 nuclear receptor-like protein 0.003 0.0053 0.0128
Toxoplasma gondii glycogen synthase, putative 0.0014 0.0006 0.0005
Trichomonas vaginalis conserved hypothetical protein 0.0021 0.0025 0.0152
Brugia malayi Nuclear hormone receptor family member nhr-25 0.003 0.0053 0.0277
Loa Loa (eye worm) hypothetical protein 0.0046 0.0099 0.0517
Leishmania major guanosine monophosphate reductase 0.0021 0.0025 0.0124
Entamoeba histolytica serine/threonine- protein kinase 6, putative 0.0169 0.0455 0.2902
Toxoplasma gondii 5'-AMP-activated protein kinase subunit beta-1 family protein, putative 0.0065 0.0155 0.0154
Mycobacterium leprae Probable fatty-acid-CoA synthetase FadD22 (fatty-acid-CoA ligase) (fatty-acid-CoA synthase) 0.0028 0.0048 0.0047
Mycobacterium leprae 3-dehydroquinate synthase AroB 0.012 0.0314 0.0592
Treponema pallidum P26 0.0014 0.0006 0.002
Toxoplasma gondii shikimate dehydrogenase substrate binding domain-containing protein 0.0309 0.0861 0.0861
Loa Loa (eye worm) hypothetical protein 0.0022 0.003 0.0158
Schistosoma mansoni hypothetical protein 0.0066 0.0155 0.0376
Echinococcus multilocularis lysine specific demethylase 6a 0.0016 0.0012 0.0013
Trichomonas vaginalis CAMK family protein kinase 0.0022 0.0028 0.0171
Schistosoma mansoni chloride channel protein 0.0021 0.0025 0.006
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0013 0.0004 0.0017
Schistosoma mansoni importin beta-1 0.003 0.0053 0.0127
Echinococcus granulosus 5' AMP activated protein kinase catalytic 0.0236 0.065 0.1571
Entamoeba histolytica protein kinase domain containing protein 0.0051 0.0113 0.0716
Echinococcus multilocularis neuroligin 0.0046 0.0099 0.0104
Echinococcus multilocularis ecdysone induced protein 78C 0.003 0.0053 0.0056
Mycobacterium tuberculosis Putative ferredoxin reductase 0.0089 0.0222 0.0446
Trypanosoma cruzi glycogen synthase kinase 3, putative 0.0051 0.0113 0.0585
Echinococcus granulosus Ataxin 2 N terminaldomain containing protein 0.0023 0.0032 0.0077
Schistosoma mansoni retinoid-x-receptor (RXR) 0.0016 0.0012 0.0028
Leishmania major hypothetical protein, conserved 0.0016 0.0012 0.0059
Trichomonas vaginalis phosphofructokinase, putative 0.0113 0.0292 0.1859
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0286 0.0796 0.5077
Plasmodium vivax ubiquitin carboxyl-terminal hydrolase 13, putative 0.0015 0.001 0.0009
Mycobacterium ulcerans non-ribosomal peptide synthetase MbtF 0.0028 0.0048 0.0044
Echinococcus multilocularis glycogen synthase kinase 3 beta 0.0051 0.0113 0.0119
Schistosoma mansoni BC026374 protein (S09 family) 0.0046 0.0099 0.0239
Echinococcus multilocularis FTZ F1 alpha 0.003 0.0053 0.0056
Echinococcus granulosus Basic leucine zipper bZIP transcription 0.0039 0.0078 0.0188
Loa Loa (eye worm) 6-phosphofructokinase 0.0113 0.0292 0.1525
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0047 0.0102 0.0107
Brugia malayi jmjC domain containing protein 0.0016 0.0012 0.0064
Loa Loa (eye worm) hypothetical protein 0.0185 0.0502 0.2621
Schistosoma mansoni nephrin 0.0022 0.003 0.0073
Trypanosoma brucei inosine-5'-monophosphate dehydrogenase 0.0021 0.0025 0.0124
Loa Loa (eye worm) hypothetical protein 0.0021 0.0025 0.0129
Trichomonas vaginalis conserved hypothetical protein 0.0021 0.0025 0.0152
Plasmodium falciparum dihydrolipoyl dehydrogenase, mitochondrial 0.0013 0.0004 0.0003
Echinococcus multilocularis cyclin dependent kinase 5 0.0048 0.0104 0.011
Echinococcus granulosus histone lysine methyltransferase setb 0.0032 0.0059 0.0142
Brugia malayi Patched family protein 0.0018 0.0018 0.0095
Trypanosoma brucei ubiquitin carboxyl-terminal hydrolase, putative 0.0039 0.0078 0.04
Loa Loa (eye worm) D-ets-4 DNA binding domain-containing protein 0.0071 0.0172 0.0896
Leishmania major cell division related protein kinase 2,cdc2-related kinase 0.0048 0.0104 0.0538
Brugia malayi hypothetical protein 0.0434 0.1224 0.6392
Trypanosoma cruzi ubiquitin carboxyl-terminal hydrolase, putative 0.0015 0.001 0.0047
Entamoeba histolytica cell division protein kinase 2, putative 0.0048 0.0104 0.0659
Loa Loa (eye worm) hypothetical protein 0.0018 0.0018 0.0095
Trichomonas vaginalis set domain proteins, putative 0.0247 0.0681 0.4345
Loa Loa (eye worm) hypothetical protein 0.0086 0.0214 0.1118
Mycobacterium ulcerans transcriptional regulator 0.0021 0.0025 0.0021
Onchocerca volvulus Casein kinase II subunit beta homolog 0.0038 0.0075 0.0542
Brugia malayi Immunoglobulin I-set domain containing protein 0.0036 0.0069 0.0361
Brugia malayi hypothetical protein 0.0014 0.0007 0.0034
Trichomonas vaginalis glutaminase, putative 0.0552 0.1567 1
Loa Loa (eye worm) 5'-AMP-activated protein kinase 0.0111 0.0287 0.1496
Schistosoma mansoni serine/threonine protein kinase 0.0236 0.065 0.1571
Echinococcus multilocularis Jumonji, AT rich interactive domain 1B 0.002 0.0022 0.0023
Echinococcus multilocularis Niemann Pick C1 protein 0.0431 0.1217 0.1283
Schistosoma mansoni protein kinase subunit gamma 0.0228 0.0627 0.1515
Brugia malayi Immunoglobulin I-set domain containing protein 0.0022 0.003 0.0158
Onchocerca volvulus Bile acid receptor homolog 0.003 0.0053 0.0383
Echinococcus granulosus phd:f box containing protein 0.0016 0.0012 0.003
Echinococcus multilocularis Immunoglobulin 0.0036 0.0069 0.0073
Loa Loa (eye worm) hypothetical protein 0.003 0.0053 0.0277
Echinococcus granulosus cyclin dependent kinase 1 0.0048 0.0104 0.0251
Trichomonas vaginalis 6-phosphofructokinase, putative 0.003 0.0053 0.0335
Loa Loa (eye worm) nuclear hormone receptor-like 1 0.0016 0.0012 0.006
Onchocerca volvulus 0.0046 0.0099 0.0713
Loa Loa (eye worm) hypothetical protein 0.0022 0.003 0.0158
Schistosoma mansoni steroid hormone receptor ad4bp 0.003 0.0053 0.0128
Echinococcus granulosus casein kinase ii subunit beta 0.0038 0.0075 0.0182
Entamoeba histolytica serine/threonine protein kinase, putative 0.0022 0.0028 0.0172
Loa Loa (eye worm) hypothetical protein 0.0014 0.0007 0.0034
Mycobacterium tuberculosis POSSIBLE PARA-NITROBENZYL ESTERASE (FRAGMENT) 0.0046 0.0099 0.0194
Loa Loa (eye worm) jmjC domain-containing protein 0.0016 0.0012 0.0064
Echinococcus granulosus H:Cl exchange transporter 3 0.0021 0.0025 0.006
Trichomonas vaginalis ap endonuclease, putative 0.0019 0.0022 0.0133
Mycobacterium ulcerans carboxylesterase, LipT 0.0046 0.0099 0.0095
Schistosoma mansoni thyroid hormone receptor 0.003 0.0053 0.0128
Schistosoma mansoni serine/threonine protein kinase 0.0016 0.0012 0.003
Leishmania major serine/threonine-protein kinase, putative 0.0022 0.0028 0.014
Trichomonas vaginalis glucosylceramidase, putative 0.0254 0.0702 0.4473
Plasmodium vivax flap endonuclease 1, putative 0.0054 0.0122 0.0121
Loa Loa (eye worm) 6-phosphofructokinase 0.0113 0.0292 0.1525
Echinococcus granulosus Nuclear hormone receptor HR96 0.0014 0.0007 0.0016
Trypanosoma cruzi chloride channel protein, putative 0.0021 0.0025 0.0124
Onchocerca volvulus 0.0028 0.0048 0.0345
Giardia lamblia Kinase, CMGC CDK 0.0048 0.0104 0.0639
Trypanosoma brucei Voltage-gated Chloride channel Like 1 0.0021 0.0025 0.0124
Schistosoma mansoni tar DNA-binding protein 0.0131 0.0344 0.0832
Loa Loa (eye worm) AUR protein kinase 0.0169 0.0455 0.2374
Echinococcus granulosus EGFP:Bcl2 fusion protein 0.0086 0.0214 0.0518
Echinococcus multilocularis contactin neuroglian septate junction protein 0.0022 0.003 0.0032
Brugia malayi Nuclear hormone receptor family member nhr-19 0.003 0.0053 0.0277
Echinococcus multilocularis BC026374 protein (S09 family) 0.0046 0.0099 0.0104
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.0028 0.0048 0.025
Loa Loa (eye worm) hypothetical protein 0.0018 0.0018 0.0095
Leishmania major acetyl-CoA synthetase, putative 0.0028 0.0048 0.0245
Plasmodium falciparum ATP-dependent 6-phosphofructokinase 0.003 0.0053 0.0053
Schistosoma mansoni serine/threonine protein kinase 0.0169 0.0455 0.1099
Echinococcus multilocularis replication factor c subunit 1 0.0021 0.0025 0.0026
Loa Loa (eye worm) latrophilin receptor protein 2 0.0066 0.0155 0.0812
Loa Loa (eye worm) hypothetical protein 0.0185 0.0503 0.2629
Trichomonas vaginalis helicase, putative 0.0013 0.0003 0.0016
Echinococcus granulosus ubiquitin carboxyl terminal hydrolase 22 0.0015 0.001 0.0024
Loa Loa (eye worm) hypothetical protein 0.0051 0.0114 0.0593
Loa Loa (eye worm) hypothetical protein 0.0021 0.0025 0.0129
Entamoeba histolytica protein kinase, putative 0.0189 0.0515 0.3284
Treponema pallidum exodeoxyribonuclease (exoA) 0.0019 0.0022 0.0221
Loa Loa (eye worm) hypothetical protein 0.0018 0.0018 0.0095
Toxoplasma gondii chloride transporter, chloride channel (ClC) family protein 0.0021 0.0025 0.0024
Mycobacterium tuberculosis Probable exodeoxyribonuclease III protein XthA (exonuclease III) (EXO III) (AP endonuclease VI) 0.0019 0.0022 0.0037
Schistosoma mansoni cell adhesion molecule 0.0022 0.003 0.0073
Echinococcus granulosus dna polymerase eta 0.0136 0.0359 0.0867
Trypanosoma cruzi aurora B kinase, putative 0.0169 0.0455 0.2371
Plasmodium vivax dihydrolipoyl dehydrogenase, mitochondrial, putative 0.0013 0.0004 0.0003
Entamoeba histolytica protein kinase , putative 0.0169 0.0455 0.2902
Brugia malayi Nuclear hormone receptor family member nhr-31 0.003 0.0053 0.0277
Loa Loa (eye worm) AUR protein kinase 0.0169 0.0455 0.2374
Mycobacterium tuberculosis Bifunctional enzyme MbtA: salicyl-AMP ligase (SAL-AMP ligase) + salicyl-S-ArCP synthetase 0.0028 0.0048 0.009
Trypanosoma brucei ATP-dependent DEAD/H DNA helicase recQ, putative 0.0021 0.0025 0.0124
Toxoplasma gondii aurora kinase 0.0169 0.0455 0.0454
Trypanosoma brucei NIMA-related protein kinase 0.0022 0.0028 0.014
Echinococcus multilocularis intestinal type alkaline phosphatase 0.0169 0.0454 0.0479
Toxoplasma gondii serine/threonine specific protein phosphatase 0.0014 0.0006 0.0005
Schistosoma mansoni transcription factor LCR-F1 0.0039 0.0078 0.0188
Echinococcus multilocularis protein dispatched 1 0.0148 0.0394 0.0416
Loa Loa (eye worm) patched family protein 0.0018 0.0018 0.0095
Trichomonas vaginalis glucosylceramidase, putative 0.0166 0.0448 0.2856
Toxoplasma gondii cell-cycle-associated protein kinase CDK, putative 0.0048 0.0104 0.0103
Leishmania major cell division protein kinase 2,cdc2-related kinase 0.0048 0.0104 0.0538
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0013 0.0004 0.0017
Onchocerca volvulus 0.0046 0.0099 0.0713
Trichomonas vaginalis conserved hypothetical protein 0.0013 0.0003 0.0016
Trichomonas vaginalis glucosylceramidase, putative 0.0254 0.0702 0.4473
Brugia malayi Immunoglobulin I-set domain containing protein 0.0022 0.003 0.0158
Mycobacterium ulcerans long-chain-acyl-CoA synthetase 0.0028 0.0048 0.0044
Trichomonas vaginalis glutathione reductase, putative 0.0013 0.0004 0.0021
Treponema pallidum diphosphate--fructose-6-phosphate 1-phosphotransferase 0.0113 0.0292 0.3636
Mycobacterium ulcerans acyl-CoA synthetase 0.0097 0.0247 0.0243
Brugia malayi Patched family protein 0.0018 0.0018 0.0095
Trichomonas vaginalis casein kinase II beta chain, putative 0.0038 0.0075 0.0474
Echinococcus multilocularis acetylcholinesterase 0.0273 0.0757 0.0798
Trypanosoma cruzi ATP-dependent DEAD/H DNA helicase recQ, putative 0.0021 0.0025 0.0124
Echinococcus granulosus roundabout 2 0.0022 0.003 0.0073
Trypanosoma cruzi DNA polymerase kappa, putative 0.0163 0.0438 0.2282
Brugia malayi Carboxylesterase family protein 0.0046 0.0099 0.0517
Leishmania major ATP-dependent phosphofructokinase 0.0113 0.0292 0.1521
Brugia malayi Corticotropin releasing factor receptor 2 precursor, putative 0.0207 0.0567 0.2959
Giardia lamblia Kinase, CAMK CAMKL 0.0048 0.0105 0.0647
Leishmania major importin beta-1 subunit, putative 0.0024 0.0036 0.0184
Plasmodium falciparum ATP-dependent DNA helicase Q1 0.0021 0.0025 0.0024
Loa Loa (eye worm) hypothetical protein 0.0014 0.0007 0.0034
Brugia malayi Patched family protein 0.0018 0.0018 0.0095
Toxoplasma gondii chorismate synthase, putative 0.3457 1 1
Schistosoma mansoni tar DNA-binding protein 0.0131 0.0344 0.0832
Toxoplasma gondii ATP-dependent DNA helicase, RecQ family protein 0.0021 0.0025 0.0024
Loa Loa (eye worm) hypothetical protein 0.0016 0.0012 0.006
Brugia malayi Carboxylesterase family protein 0.0273 0.0757 0.3953
Echinococcus granulosus neuroligin 0.0046 0.0099 0.0239
Mycobacterium ulcerans long-chain fatty-acid CoA ligase 0.0097 0.0247 0.0243
Brugia malayi Nuclear hormone receptor family member nhr-1 0.003 0.0053 0.0277
Loa Loa (eye worm) hypothetical protein 0.0016 0.0012 0.006
Mycobacterium ulcerans 3-phosphoshikimate 1-carboxyvinyltransferase 0.0309 0.0861 0.0858
Mycobacterium tuberculosis P-hydroxybenzoyl-AMP ligase FadD22 0.0028 0.0048 0.009
Schistosoma mansoni coup transcription factor 0.003 0.0053 0.0128
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0047 0.0102 0.0245
Loa Loa (eye worm) phosphofructokinase 0.0113 0.0292 0.1525
Loa Loa (eye worm) hypothetical protein 0.0125 0.0328 0.1712
Echinococcus multilocularis histone deacetylase 6 0.0672 0.1915 0.2019
Trichomonas vaginalis conserved hypothetical protein 0.0013 0.0003 0.0016
Brugia malayi jmjC domain containing protein 0.0016 0.0012 0.0064
Echinococcus multilocularis microtubule associated protein 2 0.1438 0.4139 0.4363
Echinococcus multilocularis 5' AMP activated protein kinase subunit gamma 0.0228 0.0627 0.0661
Schistosoma mansoni phosphatidylserine receptor 0.0016 0.0012 0.003
Mycobacterium ulcerans fatty-acid-CoA ligase 0.0097 0.0247 0.0243
Echinococcus multilocularis nuclear receptor subfamily 4 group A 0.0014 0.0007 0.0007
Trichomonas vaginalis conserved hypothetical protein 0.0013 0.0003 0.0016
Brugia malayi Prion-like- 0.0022 0.003 0.0158
Mycobacterium ulcerans O-succinylbenzoic acid--CoA ligase 0.0028 0.0048 0.0044
Echinococcus multilocularis terminal deoxycytidyl transferase rev1 0.0109 0.0282 0.0297
Trichomonas vaginalis histone deacetylase, putative 0.0551 0.1565 0.9987
Trypanosoma brucei dihydrolipoamide dehydrogenase 0.0013 0.0004 0.0017
Schistosoma mansoni patched 1 0.013 0.0341 0.0824
Trypanosoma cruzi histone deacetylase, putative 0.0672 0.1915 1
Echinococcus granulosus nuclear receptor 2DBD gamma 0.003 0.0053 0.0128
Loa Loa (eye worm) CAMK/MLCK protein kinase 0.0016 0.0012 0.0065
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0032 0.0059 0.0142
Loa Loa (eye worm) hypothetical protein 0.0018 0.0018 0.0095
Brugia malayi jmjC domain containing protein 0.0064 0.0152 0.0792
Echinococcus granulosus cyclin dependent kinase 5 0.0048 0.0104 0.0251
Loa Loa (eye worm) hypothetical protein 0.0018 0.0018 0.0095
Brugia malayi hypothetical protein 0.0018 0.0018 0.0095
Echinococcus granulosus histone deacetylase 3 0.0551 0.1565 0.3781
Loa Loa (eye worm) runx1 0.0054 0.0123 0.0642
Brugia malayi Nuclear hormone receptor-like 1 0.003 0.0053 0.0277
Echinococcus granulosus nuclear receptor nhr 48 0.0014 0.0007 0.0016
Schistosoma mansoni serine/threonine protein kinase 0.0048 0.0105 0.0254
Brugia malayi hypothetical protein 0.0036 0.0069 0.0361
Toxoplasma gondii phosphofructokinase PFKII 0.003 0.0053 0.0053
Mycobacterium ulcerans inosine 5'-monophosphate dehydrogenase 0.0021 0.0025 0.0021
Schistosoma mansoni histone deacetylase 4 5 0.0672 0.1915 0.4628
Giardia lamblia Kinase, CMGC GSK 0.0051 0.0113 0.0696
Schistosoma mansoni DNA polymerase IV / kappa 0.0034 0.0063 0.0153
Loa Loa (eye worm) hypothetical protein 0.0039 0.0078 0.0405
Trypanosoma brucei GMP reductase 0.0021 0.0025 0.0124
Toxoplasma gondii histone deacetylase HDAC4 0.0278 0.0773 0.0772
Echinococcus granulosus Niemann Pick C1 protein 0.0302 0.0841 0.2033
Toxoplasma gondii GTP-binding nuclear protein ran/tc4 0.0022 0.003 0.0029
Loa Loa (eye worm) nuclear hormone receptor family member nhr-41 0.003 0.0053 0.0277
Trypanosoma brucei apurinic/apyrimidinic endonuclease, putative 0.0019 0.0022 0.0108
Trypanosoma cruzi ATP-dependent 6-phosphofructokinase, glycosomal 0.0113 0.0292 0.1521
Toxoplasma gondii CBS domain-containing protein 0.0021 0.0025 0.0024
Trypanosoma cruzi mitochondrial DNA polymerase beta-PAK, putative 0.0053 0.0119 0.0619
Echinococcus multilocularis dual specificity 0.0189 0.0515 0.0542
Loa Loa (eye worm) patched family protein 0.0018 0.0018 0.0095
Echinococcus multilocularis cyclin dependent kinase 1 0.0048 0.0104 0.011
Trypanosoma brucei mitochondrial DNA polymerase beta-PAK 0.0147 0.0391 0.2039
Brugia malayi ecdysteroid receptor 0.003 0.0053 0.0277
Brugia malayi N-terminal motif family protein 0.0185 0.0503 0.2629
Loa Loa (eye worm) hypothetical protein 0.0016 0.0012 0.0064
Schistosoma mansoni acetylcholinesterase 0.0046 0.0099 0.0239
Trichomonas vaginalis histone deacetylase 1, 2 ,3, putative 0.0551 0.1565 0.9987
Echinococcus granulosus COUP TF:Svp nuclear hormone receptor 0.003 0.0053 0.0128
Trichomonas vaginalis conserved hypothetical protein 0.0013 0.0003 0.0016
Toxoplasma gondii histone deacetylase HDAC3 0.0551 0.1565 0.1564
Brugia malayi hypothetical protein 0.0033 0.0061 0.0318
Loa Loa (eye worm) CMGC/CDK/CDC2 protein kinase 0.0048 0.0104 0.0543
Loa Loa (eye worm) nucleolar RNA-associated protein alpha 0.0322 0.0901 0.4703
Loa Loa (eye worm) chloride channel protein 7 0.0021 0.0025 0.0129
Loa Loa (eye worm) RNA binding protein 0.0131 0.0344 0.1797
Brugia malayi steroid hormone receptor 0.003 0.0053 0.0277
Brugia malayi Ubiquitin carboxyl-terminal hydrolase family protein 0.0015 0.001 0.0052
Schistosoma mansoni hypothetical protein 0.0125 0.0328 0.0791
Plasmodium falciparum ataxin-2 like protein, putative 0.0051 0.0114 0.0113
Loa Loa (eye worm) hypothetical protein 0.0046 0.0099 0.0517
Loa Loa (eye worm) hypothetical protein 0.0018 0.0018 0.0095
Mycobacterium ulcerans acyl-CoA synthetase 0.0097 0.0247 0.0243
Loa Loa (eye worm) histone methyltransferase 0.0019 0.0021 0.0108
Mycobacterium tuberculosis Probable cystathionine beta-synthase Cbs (serine sulfhydrase) (beta-thionase) (hemoprotein H-450) 0.0021 0.0025 0.0043
Plasmodium vivax JmjC domain containing protein 0.0016 0.0012 0.0011
Echinococcus granulosus twitchin 0.0052 0.0116 0.0281
Loa Loa (eye worm) CMGC/DYRK/DYRK1 protein kinase 0.0189 0.0515 0.2686
Toxoplasma gondii NEK kinase 0.0022 0.0028 0.0027
Wolbachia endosymbiont of Brugia malayi IMP dehydrogenase 0.0021 0.0025 0.0404
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0286 0.0796 0.5077
Loa Loa (eye worm) hypothetical protein 0.0021 0.0025 0.0129
Echinococcus multilocularis Nuclear hormone receptor HR96 0.0014 0.0007 0.0007
Echinococcus granulosus lysine specific demethylase 5A 0.0064 0.0152 0.0366
Trypanosoma cruzi Domain of unknown function DUF21, putative 0.0021 0.0025 0.0124
Brugia malayi orphan nuclear receptor NR2E1 0.0014 0.0007 0.0034
Toxoplasma gondii LsmAD domain-containing protein 0.0051 0.0114 0.0113
Trypanosoma cruzi trypanothione reductase, putative 0.0013 0.0004 0.0017
Brugia malayi TAR-binding protein 0.0131 0.0344 0.1797
Trypanosoma brucei protein kinase, putative 0.0051 0.0113 0.0585
Schistosoma mansoni nuclear hormone receptor 0.0014 0.0007 0.0016
Schistosoma mansoni phd/f-box containing protein 0.0016 0.0012 0.003
Brugia malayi photoreceptor-specific nuclear receptor 0.003 0.0053 0.0277
Loa Loa (eye worm) hypothetical protein 0.0018 0.0018 0.0095
Echinococcus multilocularis expressed conserved protein 0.0284 0.0788 0.0831
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.003 0.0053 0.0277
Plasmodium falciparum histone deacetylase 1 0.0551 0.1565 0.1564
Schistosoma mansoni cell adhesion molecule 0.0046 0.0099 0.024
Wolbachia endosymbiont of Brugia malayi exonuclease III 0.0019 0.0022 0.0344
Trypanosoma brucei 5'-AMP-activated protein kinase catalytic subunit alpha, putative 0.0048 0.0105 0.0545
Brugia malayi Ets-domain containing protein 0.0071 0.0172 0.0896
Brugia malayi glutaminase DH11.1 0.0552 0.1567 0.8181
Brugia malayi histone deacetylase 11 0.0278 0.0773 0.4033
Onchocerca volvulus 0.0473 0.1338 0.9651
Trichomonas vaginalis conserved hypothetical protein 0.0013 0.0003 0.0016
Trypanosoma brucei unspecified product 0.0075 0.0184 0.0955
Trichomonas vaginalis DNA helicase recq1, putative 0.0021 0.0025 0.0152
Toxoplasma gondii pyruvate dehydrogenase complex subunit PDH-E3II 0.0013 0.0004 0.0003
Loa Loa (eye worm) immunoglobulin I-set domain-containing protein 0.0022 0.003 0.0158
Brugia malayi Histone deacetylase family protein 0.0672 0.1915 1
Trichomonas vaginalis casein kinase II beta chain, putative 0.0038 0.0075 0.0474
Brugia malayi Patched family protein 0.0018 0.0018 0.0095
Brugia malayi histone deacetylase 1 (HD1) 0.0551 0.1565 0.817
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0013 0.0003 0.0016
Trypanosoma brucei flap endonuclease-1 (FEN-1), putative 0.0054 0.0122 0.0632
Loa Loa (eye worm) patched family protein 0.0018 0.0018 0.0095
Leishmania major serine/threonine-protein kinase, putative,protein kinase, putative 0.0189 0.0515 0.2683
Entamoeba histolytica serine/threonine- protein kinase 6 , putative 0.0169 0.0455 0.2902
Loa Loa (eye worm) hypothetical protein 0.0018 0.0018 0.0095
Brugia malayi serine/threonine kinase 12 0.0169 0.0455 0.2374
Mycobacterium ulcerans UDP-N-acetylglucosamine 1-carboxyvinyltransferase 0.0189 0.0513 0.0509
Trypanosoma cruzi histone deacetylase, putative 0.0672 0.1915 1
Leishmania major hypothetical protein, conserved 0.0021 0.0025 0.0124
Loa Loa (eye worm) jmjC domain-containing protein 0.0064 0.0152 0.0792
Echinococcus granulosus GTP binding nuclear protein Ran 0.0022 0.003 0.0072
Trypanosoma brucei PAB1-binding protein , putative 0.0051 0.0114 0.0589
Loa Loa (eye worm) hypothetical protein 0.0066 0.0155 0.0812
Plasmodium falciparum histone deacetylase 2 0.0672 0.1915 0.1915
Plasmodium falciparum thioredoxin reductase 0.0039 0.0078 0.0077
Leishmania major 4-coumarate:coa ligase-like protein 0.0097 0.0247 0.1284
Brugia malayi ATP-dependent DNA helicase, RecQ family protein 0.0021 0.0025 0.0129
Trypanosoma cruzi chloride channel protein, putative 0.0021 0.0025 0.0124
Plasmodium vivax histone deacetylase, putative 0.0278 0.0773 0.0772
Echinococcus granulosus GA binding protein alpha chain 0.0071 0.0172 0.0415
Echinococcus granulosus carboxylesterase 5A 0.0273 0.0757 0.1829
Trichomonas vaginalis CAMK family protein kinase 0.0022 0.0028 0.0171
Plasmodium falciparum glycogen synthase kinase 3 0.0051 0.0113 0.0112
Giardia lamblia DNA damage repair protein 0.0034 0.0063 0.038
Loa Loa (eye worm) TAR-binding protein 0.0131 0.0344 0.1797
Echinococcus granulosus Bcl 2 ous antagonist:killer 0.0086 0.0214 0.0518
Echinococcus multilocularis alkaline phosphatase, intestinal, gene 2 0.0169 0.0454 0.0479
Brugia malayi CLC chloride channel protein 0.0021 0.0025 0.0129
Loa Loa (eye worm) hypothetical protein 0.0434 0.1224 0.6392
Echinococcus multilocularis retinoic acid receptor rxr beta a retinoic acid receptor rxr alpha a retinoic acid receptor rxr alpha 0.0014 0.0007 0.0007
Trichomonas vaginalis STE family protein kinase 0.0022 0.0028 0.0171
Brugia malayi Nuclear hormone receptor family member nhr-41 0.003 0.0053 0.0277
Brugia malayi Nuclear hormone receptor family member nhr-14 0.003 0.0053 0.0277
Leishmania major ATP-dependent DEAD/H DNA helicase recQ, putative 0.0021 0.0025 0.0124
Trypanosoma brucei unspecified product 0.0075 0.0184 0.0955
Trypanosoma brucei DNA polymerase beta thumb, putative 0.0044 0.0092 0.0474
Echinococcus multilocularis cadherin EGF LAG seven pass G type receptor 0.0066 0.0155 0.0164
Echinococcus multilocularis neurotracting:lsamp:neurotrimin:obcam 0.0022 0.003 0.0032
Brugia malayi phosphofructokinase 0.0113 0.0292 0.1525
Trichomonas vaginalis glucosylceramidase, putative 0.0166 0.0448 0.2856
Loa Loa (eye worm) hypothetical protein 0.0073 0.0176 0.0917
Mycobacterium ulcerans hypothetical protein 0.0021 0.0025 0.0021
Echinococcus multilocularis tumor protein p63 0.0354 0.0992 0.1046
Brugia malayi GTP-binding nuclear protein RAN/TC4 0.0022 0.003 0.0155
Loa Loa (eye worm) ubiquitin carboxyl-terminal hydrolase 0.0015 0.001 0.0052
Brugia malayi acetyl-Coenzyme A synthetase 2 0.0028 0.0048 0.025
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0286 0.0796 0.5077
Echinococcus granulosus nibrin 0.0021 0.0025 0.006
Trichomonas vaginalis CAMK family protein kinase 0.0048 0.0105 0.0666
Brugia malayi hypothetical protein 0.0014 0.0007 0.0034
Leishmania major GTP-binding protein, putative 0.0022 0.003 0.015
Echinococcus granulosus Jumonji AT rich interactive domain 1B 0.002 0.0022 0.0053
Trypanosoma brucei hypothetical protein, conserved 0.0034 0.0063 0.0327
Echinococcus multilocularis ubiquitin carboxyl terminal hydrolase 8 0.0039 0.0078 0.0082
Toxoplasma gondii histone deacetylase HDAC2 0.0551 0.1565 0.1564
Echinococcus granulosus tyrosine protein kinase transmembrane receptor 0.0017 0.0013 0.0033
Echinococcus granulosus dual specificity 0.0189 0.0515 0.1243
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0047 0.0102 0.0245
Entamoeba histolytica protein kinase, putative 0.0169 0.0455 0.2902
Mycobacterium leprae PROBABLE FATTY-ACID-CoA LIGASE FADD7 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) 0.0097 0.0247 0.0454
Giardia lamblia Casein kinase II beta chain 0.0038 0.0075 0.0455
Echinococcus multilocularis roundabout 2 0.0058 0.0134 0.0141
Plasmodium vivax ataxin-2 like protein, putative 0.0051 0.0114 0.0113
Loa Loa (eye worm) hypothetical protein 0.0014 0.0007 0.0034
Loa Loa (eye worm) ImpB/MucB/SamB family protein 0.0109 0.0282 0.1473
Plasmodium falciparum protein MAM3, putative 0.0021 0.0025 0.0024
Echinococcus multilocularis serine:threonine kinase SAD 1 0.0048 0.0105 0.0111
Trypanosoma cruzi JmjC domain, hydroxylase, putative 0.0016 0.0012 0.0059
Loa Loa (eye worm) TK protein kinase 0.0017 0.0013 0.007
Echinococcus granulosus importin subunit beta 1 0.003 0.0053 0.0127
Echinococcus multilocularis casein kinase ii subunit beta 0.0038 0.0075 0.0079
Trichomonas vaginalis DNA polymerase IV / kappa, putative 0.0163 0.0438 0.2789
Leishmania major protein kinase, putative 0.0022 0.0028 0.014
Echinococcus multilocularis twitchin 0.0016 0.0012 0.0013
Schistosoma mansoni hypothetical protein 0.0086 0.0214 0.0518
Plasmodium falciparum serine/threonine protein kinase, putative 0.0169 0.0455 0.0454
Schistosoma mansoni hypothetical protein 0.083 0.2375 0.5738
Mycobacterium tuberculosis POSSIBLE PARA-NITROBENZYL ESTERASE (FRAGMENT) 0.0046 0.0099 0.0194
Trypanosoma cruzi chloride channel protein, putative 0.0021 0.0025 0.0124
Giardia lamblia Hypothetical protein 0.0021 0.0025 0.0131
Mycobacterium ulcerans DNA polymerase IV 0.0163 0.0438 0.0434
Giardia lamblia Histone deacetylase 0.0551 0.1565 1
Loa Loa (eye worm) hypothetical protein 0.0021 0.0025 0.0129
Trichomonas vaginalis conserved hypothetical protein 0.0013 0.0003 0.0016
Schistosoma mansoni titin 0.0022 0.003 0.0073
Schistosoma mansoni cell adhesion molecule 0.0022 0.003 0.0073
Loa Loa (eye worm) histone deacetylase 7A 0.0672 0.1915 1
Brugia malayi latrophilin 2 splice variant baaae 0.0142 0.0376 0.1965
Trypanosoma brucei AMP-activated protein kinase, gamma regulatory subunit 0.0021 0.0025 0.0124
Entamoeba histolytica recQ family helicase, putative 0.0021 0.0025 0.0152
Brugia malayi protein C24B5.3 0.0018 0.0018 0.0095
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0015 0.001 0.0058
Leishmania major ubiquitin hydrolase, putative,cysteine peptidase, Clan CA, family C19, putative 0.0015 0.001 0.0047
Echinococcus multilocularis jumonji domain containing 1A 0.0016 0.0012 0.0013
Leishmania major dihydrolipoamide dehydrogenase, putative 0.0013 0.0004 0.0017
Schistosoma mansoni inosine-5-monophosphate dehydrogenase 0.0021 0.0025 0.006
Mycobacterium ulcerans non-ribosomal peptide synthetase MbtE 0.0028 0.0048 0.0044
Loa Loa (eye worm) steroid hormone receptor 0.003 0.0053 0.0277
Brugia malayi Immunoglobulin I-set domain containing protein 0.0016 0.0012 0.0065
Schistosoma mansoni rab geranylgeranyl transferase alpha subunit 0.0109 0.0282 0.0682
Toxoplasma gondii HEAT repeat-containing protein 0.003 0.0053 0.0052
Loa Loa (eye worm) hypothetical protein 0.0018 0.0018 0.0095
Brugia malayi 5'-AMP-activated protein kinase, beta subunit, complex-interacting region containing protein 0.0111 0.0287 0.1496
Trypanosoma cruzi AMP-activated protein kinase, gamma regulatory subunit 0.0021 0.0025 0.0124
Leishmania major 4-coumarate:coa ligase-like protein 0.0097 0.0247 0.1284
Mycobacterium ulcerans acyl-CoA synthetase 0.0028 0.0048 0.0044
Echinococcus multilocularis ATP dependent DNA helicase Q1 0.0021 0.0025 0.0026
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0039 0.0078 0.0489
Plasmodium vivax histone deacetylase 1, putative 0.0551 0.1565 0.1564
Trypanosoma brucei Serine/threonine-protein kinase NEK16, putative 0.0022 0.0028 0.014
Toxoplasma gondii thioredoxin reductase 0.0039 0.0078 0.0077
Echinococcus multilocularis Basic leucine zipper (bZIP) transcription 0.0039 0.0078 0.0082
Toxoplasma gondii histone kinase SNF1, putative 0.0048 0.0105 0.0104
Echinococcus granulosus Peptidase C19 ubiquitin carboxyl terminal hydrolase 2 0.0039 0.0078 0.0187
Schistosoma mansoni protein kinase subunit beta 0.0014 0.0006 0.0014
Trichomonas vaginalis CMGC family protein kinase 0.0048 0.0104 0.0658
Trichomonas vaginalis Importin beta-1 subunit, putative 0.0024 0.0036 0.0225
Onchocerca volvulus 0.0046 0.0099 0.0713
Trichomonas vaginalis CAMK family protein kinase 0.0048 0.0105 0.0666
Echinococcus granulosus dnaJ subfamily B 0.083 0.2375 0.5738
Giardia lamblia Kinase, CMGC GSK 0.0051 0.0113 0.0696
Schistosoma mansoni nuclear receptor 0.0014 0.0007 0.0016
Mycobacterium ulcerans acyl-CoA synthetase 0.0028 0.0048 0.0044
Brugia malayi Flap endonuclease-1 0.0054 0.0122 0.0637
Trichomonas vaginalis CAMK family protein kinase 0.0048 0.0105 0.0666
Brugia malayi Patched family protein 0.0018 0.0018 0.0095
Toxoplasma gondii CBS family protein 0.0021 0.0025 0.0024
Loa Loa (eye worm) hypothetical protein 0.0021 0.0025 0.0129
Loa Loa (eye worm) hypothetical protein 0.0097 0.0247 0.1289
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0014 0.0007 0.0016
Schistosoma mansoni neuroglian 0.0022 0.003 0.0073
Loa Loa (eye worm) pigment dispersing factor receptor c 0.0207 0.0567 0.2959
Mycobacterium tuberculosis Probable membrane NADH dehydrogenase NdhA 0.0089 0.0222 0.0446
Echinococcus multilocularis lysine specific demethylase 5A 0.0061 0.0142 0.015
Mycobacterium tuberculosis NAD(P)H quinone reductase LpdA 0.0099 0.0251 0.0504
Schistosoma mansoni ran 0.0022 0.003 0.0072
Loa Loa (eye worm) TK/KIN16 protein kinase 0.0524 0.1486 0.7758
Schistosoma mansoni DNA ligase IV 0.0021 0.0025 0.006
Leishmania major CBS domain protein, conserved 0.0021 0.0025 0.0124
Echinococcus multilocularis aurora kinase A 0.0169 0.0455 0.0479
Toxoplasma gondii Acetyl-coenzyme A synthetase 2, putative 0.0028 0.0048 0.0047
Loa Loa (eye worm) MH2 domain-containing protein 0.0124 0.0324 0.1693
Echinococcus multilocularis mixed lineage leukemia protein mll 0.0016 0.001 0.0011
Brugia malayi ancient conserved domain protein 2 0.0021 0.0025 0.0129
Echinococcus granulosus BRCA1 associated protein 0.0012 0.0001 0.0002
Schistosoma mansoni jumonji domain containing protein 0.0061 0.0142 0.0343
Entamoeba histolytica hypothetical protein 0.0039 0.0078 0.0492
Loa Loa (eye worm) hypothetical protein 0.0048 0.0105 0.0549
Schistosoma mansoni nuclear hormone receptor 0.003 0.0053 0.0128
Giardia lamblia Fructose-bisphosphate aldolase 0.0286 0.0796 0.5073
Schistosoma mansoni lozenge 0.0054 0.0123 0.0297
Trypanosoma cruzi JmjC domain, hydroxylase, putative 0.0016 0.0012 0.0059
Loa Loa (eye worm) RNA recognition domain-containing protein domain-containing protein 0.0131 0.0344 0.1797
Echinococcus multilocularis nuclear receptor nhr 48 0.0014 0.0007 0.0007
Echinococcus granulosus receptor type tyrosine protein phosphatase 0.0022 0.003 0.0073
Trypanosoma cruzi GMP reductase 0.0021 0.0025 0.0124
Loa Loa (eye worm) CMGC/CDK/CDK5 protein kinase 0.0048 0.0104 0.0543
Schistosoma mansoni cell adhesion molecule 0.0022 0.003 0.0073
Trypanosoma cruzi DNA damage repair protein, putative 0.0034 0.0063 0.0327
Echinococcus granulosus snurportin 1 0.0322 0.0901 0.2176
Loa Loa (eye worm) hypothetical protein 0.0016 0.0012 0.006
Echinococcus multilocularis Nuclear hormone receptor HR96 0.0014 0.0007 0.0007
Echinococcus granulosus histone deacetylase 6 0.0672 0.1915 0.4628
Loa Loa (eye worm) hypothetical protein 0.003 0.0053 0.0275
Plasmodium falciparum flap endonuclease 1 0.0054 0.0122 0.0121
Echinococcus granulosus nuclear receptor subfamily 1 group D 0.0016 0.0012 0.0028
Echinococcus multilocularis family S9 non peptidase ue (S09 family) 0.0046 0.0099 0.0104
Echinococcus multilocularis thyroid hormone receptor alpha 0.003 0.0053 0.0056
Brugia malayi glutathione reductase 0.0039 0.0078 0.0407
Loa Loa (eye worm) Csnk2b protein 0.0038 0.0075 0.0392
Loa Loa (eye worm) hypothetical protein 0.0014 0.0007 0.0034
Mycobacterium tuberculosis Probable chain -fatty-acid-CoA ligase FadD13 (fatty-acyl-CoA synthetase) 0.0097 0.0247 0.0495
Plasmodium falciparum ADP-dependent DNA helicase RecQ 0.0021 0.0025 0.0024
Echinococcus multilocularis histone lysine N methyltransferase MLL3 0.0016 0.001 0.0011
Mycobacterium ulcerans inosine 5-monophosphate dehydrogenase 0.0021 0.0025 0.0021
Trichomonas vaginalis conserved hypothetical protein 0.0013 0.0003 0.0016
Trypanosoma cruzi PAB1-binding protein , putative 0.0051 0.0114 0.0589
Loa Loa (eye worm) hypothetical protein 0.0014 0.0007 0.0034
Echinococcus multilocularis FTZ F1 nuclear receptor protein 0.003 0.0053 0.0056
Echinococcus multilocularis phd:f box containing protein 0.0016 0.0012 0.0013
Brugia malayi Patched protein homolog 1 0.0018 0.0018 0.0095
Leishmania major mitochondrial DNA polymerase beta 0.031 0.0866 0.4517
Trypanosoma brucei ubiquitin carboxyl-terminal hydrolase, putative 0.0015 0.001 0.0047
Schistosoma mansoni DNA helicase recq5 0.0021 0.0025 0.006
Entamoeba histolytica casein kinase II regulatory subunit family protein 0.0038 0.0075 0.0475
Loa Loa (eye worm) hypothetical protein 0.0022 0.003 0.0158
Trichomonas vaginalis spcc417.12 protein, putative 0.0046 0.0099 0.0626
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0032 0.0059 0.0142
Echinococcus multilocularis H(+):Cl() exchange transporter 7 0.0021 0.0025 0.0026
Plasmodium vivax SET domain protein, putative 0.0032 0.0059 0.0058
Plasmodium vivax histone acetyltransferase GCN5, putative 0.0044 0.0093 0.0092
Echinococcus multilocularis roundabout 2 0.0022 0.003 0.0032
Echinococcus multilocularis inosine 5' monophosphate dehydrogenase 2 0.0021 0.0025 0.0026
Trypanosoma brucei cdc2-related kinase 3 0.0048 0.0104 0.0538
Loa Loa (eye worm) ATP-dependent DNA helicase 0.0021 0.0025 0.0129
Echinococcus multilocularis AMPK beta subunit 0.0111 0.0287 0.0302
Plasmodium falciparum ataxin-2 like protein, putative 0.0051 0.0114 0.0113
Loa Loa (eye worm) hypothetical protein 0.0036 0.0069 0.0361
Schistosoma mansoni titin 0.0016 0.0012 0.003
Loa Loa (eye worm) glutaminase 2 0.0552 0.1567 0.8181
Trypanosoma brucei DNA polymerase kappa, putative 0.0163 0.0438 0.2282
Mycobacterium ulcerans hypothetical protein 0.0034 0.0063 0.0059
Echinococcus granulosus histone acetyltransferase KAT2B 0.0044 0.0093 0.0225
Onchocerca volvulus 0.0051 0.0113 0.0814
Trichomonas vaginalis glucosylceramidase, putative 0.0166 0.0448 0.2856
Leishmania major DNA polymerase kappa, putative 0.0123 0.0321 0.1671
Plasmodium vivax AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.0019 0.0022 0.0021
Brugia malayi Nuclear hormone receptor family member nhr-49 0.003 0.0053 0.0277
Trichomonas vaginalis glucosylceramidase, putative 0.0166 0.0448 0.2856
Trypanosoma cruzi Casein kinase II subunit beta, putative 0.0038 0.0075 0.0388
Trichomonas vaginalis CAMK family protein kinase 0.0048 0.0105 0.0666
Echinococcus multilocularis Protein lozenge 0.0054 0.0123 0.013
Schistosoma mansoni histone deacetylase 4 5 0.0672 0.1915 0.4628
Echinococcus granulosus expressed conserved protein 0.0284 0.0788 0.1904
Loa Loa (eye worm) hypothetical protein 0.0036 0.0069 0.0361
Trypanosoma brucei chrX additional, unordered contigs 0.0034 0.0063 0.0327
Brugia malayi hypothetical protein 0.0018 0.0018 0.0095
Entamoeba histolytica serine/threonine protein kinase, putative 0.0048 0.0105 0.0667
Schistosoma mansoni histone-lysine n-methyltransferase suv9 0.0032 0.0059 0.0142
Plasmodium vivax serine/threonine-protein kinase NEK4, putative 0.0022 0.0028 0.0027
Trypanosoma brucei DNA damage repair protein, putative 0.0034 0.0063 0.0327
Brugia malayi calcium-independent alpha-latrotoxin receptor 2, putative 0.0066 0.0155 0.0812
Trypanosoma brucei ubiquitin carboxyl-terminal hydrolase, putative 0.0015 0.001 0.0047
Echinococcus multilocularis SNF4:AMP activated protein kinase gamma subunit 0.0021 0.0025 0.0026
Loa Loa (eye worm) CAMK protein kinase 0.0016 0.0012 0.0065
Echinococcus multilocularis histone deacetylase 1 0.0551 0.1565 0.1649
Entamoeba histolytica phosphofructokinase, putative 0.0113 0.0292 0.1862
Chlamydia trachomatis Mg++ transporter 0.0021 0.0025 0.0021
Echinococcus multilocularis Bcl 2 ous antagonist:killer 0.0086 0.0214 0.0226
Plasmodium vivax histone deacetylase 2, putative 0.0672 0.1915 0.1915
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0015 0.001 0.0058
Echinococcus granulosus histone lysine N methyltransferase MLL3 0.0019 0.0021 0.005
Brugia malayi Patched family protein 0.0018 0.0018 0.0095
Entamoeba histolytica protein kinase, putative 0.0189 0.0515 0.3284
Echinococcus granulosus muscleblind protein 0.0611 0.174 0.4204
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0013 0.0003 0.0016
Brugia malayi chloride channel protein 7 0.0021 0.0025 0.0129
Trichomonas vaginalis histone deacetylase 1, 2 ,3, putative 0.0551 0.1565 0.9987
Echinococcus multilocularis neuroglian 0.0022 0.003 0.0032
Schistosoma mansoni hypothetical protein 0.0066 0.0155 0.0376
Loa Loa (eye worm) hypothetical protein 0.0018 0.0018 0.0095
Echinococcus granulosus acetylcholinesterase 0.0273 0.0757 0.1829
Brugia malayi Immunoglobulin I-set domain containing protein 0.0022 0.003 0.0158
Trichomonas vaginalis conserved hypothetical protein 0.0021 0.0025 0.0152
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD7 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0069 0.0164 0.0327
Schistosoma mansoni cellular tumor antigen P53 0.0052 0.0115 0.0279
Trypanosoma cruzi dihydrolipoyl dehydrogenase, putative 0.0013 0.0004 0.0017
Leishmania major apurinic/apyrimidinic endonuclease-redox protein 0.0019 0.0022 0.0108
Echinococcus granulosus lysine specific demethylase 6a 0.0016 0.0012 0.003
Echinococcus multilocularis Nuclear hormone receptor family member nhr 41 0.003 0.0053 0.0056
Entamoeba histolytica phosphofructokinase, putative 0.0113 0.0292 0.1862
Mycobacterium ulcerans hypothetical protein 0.0163 0.044 0.0436
Echinococcus granulosus GPCR family 2 0.0066 0.0155 0.0376
Schistosoma mansoni hypothetical protein 0.0322 0.0901 0.2176
Brugia malayi nuclear hormone receptor 0.003 0.0053 0.0277
Loa Loa (eye worm) AUR protein kinase 0.0169 0.0455 0.2374
Schistosoma mansoni 6-phosphofructokinase 0.0113 0.0292 0.0706
Echinococcus multilocularis protein kinase shaggy 0.0051 0.0113 0.0119
Mycobacterium tuberculosis Probable fructose-bisphosphate aldolase Fba 0.014 0.0371 0.0748
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.003 0.0053 0.0056
Loa Loa (eye worm) hypothetical protein 0.0273 0.0757 0.3953
Trypanosoma brucei histone deacetylase, putative 0.0672 0.1915 1
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0286 0.0796 0.5077
Schistosoma mansoni ets-related 0.0216 0.0592 0.143
Trypanosoma cruzi GMP reductase 0.0021 0.0025 0.0124
Leishmania major chloride channel protein, putative 0.0021 0.0025 0.0124
Plasmodium falciparum histone deacetylase, putative 0.0672 0.1915 0.1915
Loa Loa (eye worm) hypothetical protein 0.0016 0.0012 0.0064
Brugia malayi inosine-5'-monophosphate dehydrogenase family protein 0.0021 0.0025 0.0129
Loa Loa (eye worm) hypothetical protein 0.0018 0.0018 0.0095
Schistosoma mansoni chloride channel protein 0.0021 0.0025 0.006
Trichomonas vaginalis CAMK family protein kinase 0.0048 0.0105 0.0666
Mycobacterium leprae probable 3-phosphoshikimate 1-carboxyvinyl transferase AroA (5-ENOLPYRUVYLSHIKIMATE-3-PHOSPHATE SYNTHASE) (EPSP SYNTHASE) (EPSPS 0.0309 0.0861 0.1712
Brugia malayi Nuclear hormone receptor family member nhr-19 0.003 0.0053 0.0277
Echinococcus granulosus cpg binding protein 0.0062 0.0144 0.0348
Plasmodium vivax patched family protein, putative 0.0018 0.0018 0.0017
Trypanosoma cruzi leucine rich repeat protein, putative 0.0014 0.0006 0.0025
Echinococcus granulosus 5' AMP activated protein kinase subunit gamma 0.0228 0.0627 0.1515
Trichomonas vaginalis CAMK family protein kinase 0.0048 0.0105 0.0666
Mycobacterium ulcerans hypothetical protein 0.0021 0.0025 0.0021
Schistosoma mansoni serine/threonine protein kinase 0.0189 0.0515 0.1243
Brugia malayi Patched family protein 0.0018 0.0018 0.0095
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD8 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0028 0.0048 0.009
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0016 0.001 0.0025
Trypanosoma brucei DNA polymerase kappa, putative 0.0089 0.0222 0.1157
Mycobacterium ulcerans DNA polymerase IV 0.0163 0.0438 0.0434
Onchocerca volvulus Histone deacetylase 10 homolog 0.0278 0.0773 0.5571
Loa Loa (eye worm) nuclear hormone receptor family member nhr-14 0.003 0.0053 0.0277
Trypanosoma cruzi inosine-5'-monophosphate dehydrogenase, putative 0.0021 0.0025 0.0124
Onchocerca volvulus 0.0247 0.0681 0.4914
Loa Loa (eye worm) BRCA1-associated protein 2 containing protein 0.0012 0.0001 0.0005
Toxoplasma gondii histone lysine demethylase JMJC1/KDM5D/JARID1D 0.0016 0.0012 0.0011
Echinococcus multilocularis cyclin dependent kinase 5 activator 1 0.0261 0.0723 0.0762
Echinococcus granulosus cyclin dependent kinase 0.0048 0.0104 0.0251
Brugia malayi hypothetical protein 0.0051 0.0114 0.0593
Brugia malayi Nuclear hormone receptor family member nhr-25 0.003 0.0053 0.0277
Loa Loa (eye worm) hypothetical protein 0.0036 0.0069 0.0361
Brugia malayi Apoptosis regulator proteins, Bcl-2 family protein 0.0086 0.0214 0.1118
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0015 0.001 0.0058
Echinococcus granulosus terminal deoxycytidyl transferase rev1 0.0109 0.0282 0.0682
Schistosoma mansoni cyclin-dependent kinase 5 activator 0.0261 0.0723 0.1747
Schistosoma mansoni gcn5proteinral control of amino-acid synthesis 5-like 2 gcnl2 0.015 0.0401 0.0969
Trypanosoma cruzi DNA polymerase eta, putative 0.006 0.014 0.0727
Echinococcus granulosus neurotracting:lsamp:neurotrimin:obcam 0.0046 0.0099 0.024
Brugia malayi polk-prov protein 0.0088 0.0219 0.1144
Loa Loa (eye worm) CAMK/MLCK protein kinase 0.0027 0.0043 0.0223
Echinococcus granulosus cadherin EGF LAG seven pass G type receptor 0.0066 0.0155 0.0376
Echinococcus granulosus microtubule associated protein 2 0.1438 0.4139 1
Onchocerca volvulus 0.0014 0.0007 0.0048
Trichomonas vaginalis CAMK family protein kinase 0.0048 0.0105 0.0666
Trichomonas vaginalis antibiotic synthetase, putative 0.0028 0.0048 0.0299
Brugia malayi Histone deacetylase 1 0.0551 0.1565 0.817
Schistosoma mansoni hypothetical protein 0.0039 0.0078 0.0188
Mycobacterium ulcerans acyl-CoA synthetase 0.0028 0.0048 0.0044
Treponema pallidum Mg2+ transport protein (mgtE) 0.0021 0.0025 0.0259
Loa Loa (eye worm) hypothetical protein 0.0016 0.0012 0.006
Echinococcus multilocularis histone deacetylase 3 0.0551 0.1565 0.1649
Mycobacterium tuberculosis Probable inosine-5'-monophosphate dehydrogenase GuaB2 (imp dehydrogenase) (inosinic acid dehydrogenase) (inosinate dehydrogenase 0.0021 0.0025 0.0043
Toxoplasma gondii CBS domain-containing protein 0.0021 0.0025 0.0024
Loa Loa (eye worm) hypothetical protein 0.0018 0.0018 0.0095
Loa Loa (eye worm) hypothetical protein 0.0018 0.0018 0.0095
Echinococcus granulosus Nuclear hormone receptor family member nhr 41 0.003 0.0053 0.0128
Brugia malayi nuclear hormone receptor 0.0014 0.0007 0.0034
Echinococcus multilocularis ubiquitin specific protease 41 0.0039 0.0078 0.0082
Leishmania major 4-coumarate:coa ligase-like protein 0.0097 0.0247 0.1284
Plasmodium vivax dihydrolipoyl dehydrogenase, apicoplast, putative 0.0013 0.0004 0.0003
Brugia malayi hypothetical protein 0.0044 0.0093 0.0484
Schistosoma mansoni DNA polymerase eta 0.0136 0.0359 0.0867
Echinococcus granulosus serine:threonine kinase SAD 1 0.0048 0.0105 0.0254
Echinococcus granulosus peroxidasin 0.0022 0.003 0.0073
Trypanosoma brucei mitochondrial DNA polymerase beta 0.031 0.0866 0.4517
Loa Loa (eye worm) carboxylesterase 0.0046 0.0099 0.0517
Brugia malayi conserved hypotetical protein 0.0014 0.0007 0.0034
Trichomonas vaginalis CAMK family protein kinase 0.0048 0.0105 0.0666
Trypanosoma cruzi ubiquitin carboxyl-terminal hydrolase, putative 0.0039 0.0078 0.04
Echinococcus multilocularis titin 0.0016 0.0012 0.0013
Loa Loa (eye worm) nuclear hormone receptor family member nhr-31 0.003 0.0053 0.0277
Mycobacterium tuberculosis Peptide synthetase MbtF (peptide synthase) 0.0028 0.0048 0.009
Loa Loa (eye worm) O-glycosyl hydrolase family 30 protein 0.0254 0.0702 0.3662
Onchocerca volvulus 0.0018 0.0018 0.0131
Loa Loa (eye worm) nuclear receptor nhr-7B 0.0014 0.0007 0.0034
Loa Loa (eye worm) hypothetical protein 0.0018 0.0018 0.0095
Trypanosoma cruzi apurinic/apyrimidinic endonuclease 0.0019 0.0022 0.0108
Entamoeba histolytica protein kinase domain containing protein 0.0051 0.0113 0.0716
Giardia lamblia Kinase, NEK 0.0022 0.0028 0.0151
Treponema pallidum DNA ligase (lig) 0.0021 0.0025 0.0258
Brugia malayi serine/threonine protein kinase 6 0.0169 0.0455 0.2374
Echinococcus granulosus intestinal type alkaline phosphatase 0.0169 0.0454 0.1098
Mycobacterium ulcerans acyl-CoA synthetase 0.0028 0.0048 0.0044
Loa Loa (eye worm) hypothetical protein 0.0016 0.0012 0.006
Brugia malayi AMP-binding enzyme family protein 0.0028 0.0048 0.025
Echinococcus multilocularis JmjC domain containing protein 4 0.0016 0.0012 0.0013
Loa Loa (eye worm) hypothetical protein 0.0014 0.0007 0.0034
Loa Loa (eye worm) hypothetical protein 0.0046 0.0099 0.0517
Trypanosoma brucei DNA polymerase kappa, putative 0.0163 0.0438 0.2282
Onchocerca volvulus Nuclear receptor subfamily 6 group A member 1 homolog 0.0014 0.0007 0.0048
Trypanosoma cruzi hypothetical protein, conserved 0.0021 0.0025 0.0124
Trypanosoma cruzi hypothetical protein, conserved 0.0034 0.0063 0.0327
Trypanosoma brucei DNA polymerase kappa, putative 0.0089 0.0222 0.1157
Echinococcus multilocularis Niemann Pick C1 protein 0.0302 0.0841 0.0887
Mycobacterium tuberculosis Fatty-acid-CoA synthetase FadD17 (fatty-acid-CoA synthase) (fatty-acid-CoA ligase) 0.0028 0.0048 0.009
Echinococcus granulosus H:Cl exchange transporter 7 0.0021 0.0025 0.006
Brugia malayi protein unc-22 0.0016 0.0012 0.0065
Schistosoma mansoni topbp1 0.0021 0.0025 0.006
Loa Loa (eye worm) hypothetical protein 0.0018 0.0018 0.0095
Echinococcus multilocularis ubiquitin carboxyl terminal hydrolase 22 0.0015 0.001 0.0011
Echinococcus granulosus histone deacetylase 6 0.0672 0.1915 0.4628
Loa Loa (eye worm) hypothetical protein 0.0018 0.0018 0.0095
Mycobacterium tuberculosis Probable peptide synthetase Nrp (peptide synthase) 0.0028 0.0048 0.009
Loa Loa (eye worm) hypothetical protein 0.0022 0.003 0.0158
Echinococcus granulosus mixed lineage leukemia protein mll 0.0016 0.001 0.0025
Schistosoma mansoni serine/threonine protein kinase 0.0016 0.0012 0.003
Schistosoma mansoni dihydrolipoamide dehydrogenase 0.0013 0.0004 0.001
Entamoeba histolytica deoxycytidyl transferase, putative 0.0109 0.0282 0.1798
Schistosoma mansoni hypothetical protein 0.0088 0.0219 0.053
Plasmodium vivax serine/threonine protein kinase 6, putative 0.0169 0.0455 0.0454
Loa Loa (eye worm) hypothetical protein 0.0046 0.0099 0.0517
Leishmania major protein kinase, putative,serine/threonine-protein kinase Nek1, putative 0.0022 0.0028 0.014
Plasmodium vivax U4/U6.U5 tri-snRNP-associated protein 2, putative 0.0015 0.001 0.0009
Brugia malayi Amyloid A4 extracellular domain containing protein 0.034 0.0953 0.4976
Onchocerca volvulus 0.0097 0.0247 0.178
Toxoplasma gondii histone lysine methyltransferase SET/SUV39 0.0032 0.0059 0.0058
Loa Loa (eye worm) hypothetical protein 0.0185 0.0502 0.2621
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0015 0.001 0.0058
Echinococcus multilocularis flap endonuclease 1 0.0054 0.0122 0.0129
Echinococcus granulosus histone deacetylase 0.0672 0.1915 0.4628
Mycobacterium tuberculosis Peptide synthetase MbtE (peptide synthase) 0.0028 0.0048 0.009
Brugia malayi O-Glycosyl hydrolase family 30 protein 0.0254 0.0702 0.3662
Trypanosoma cruzi histone deacetylase, putative 0.0672 0.1915 1
Trichomonas vaginalis CAMK family protein kinase 0.0048 0.0105 0.0666
Echinococcus multilocularis serine:threonine protein kinase Nek1 0.0017 0.0015 0.0016
Loa Loa (eye worm) hypothetical protein 0.0022 0.003 0.0158
Entamoeba histolytica protein kinase, putative 0.0169 0.0455 0.2902
Loa Loa (eye worm) patched family protein 0.0018 0.0018 0.0095
Mycobacterium tuberculosis Conserved hypothetical membrane protein 0.0021 0.0025 0.0043
Loa Loa (eye worm) hypothetical protein 0.0021 0.0025 0.0129
Schistosoma mansoni ap endonuclease 0.0019 0.0022 0.0052
Brugia malayi Protein kinase domain containing protein 0.0048 0.0104 0.0543
Loa Loa (eye worm) hypothetical protein 0.0036 0.0069 0.0361
Mycobacterium tuberculosis Probable chorismate synthase AroF (5-enolpyruvylshikimate-3-phosphate phospholyase) 0.1705 0.4913 1
Trichomonas vaginalis phosphofructokinase, putative 0.003 0.0053 0.0335
Loa Loa (eye worm) hypothetical protein 0.0268 0.0744 0.3882
Entamoeba histolytica Niemann-Pick C1 protein, putative 0.0302 0.0841 0.5373
Schistosoma mansoni alkaline phosphatase 0.0169 0.0454 0.1098
Wolbachia endosymbiont of Brugia malayi UDP-N-acetylglucosamine 1-carboxyvinyltransferase 0.0189 0.0513 1
Plasmodium vivax acetyl-CoA synthetase, putative 0.0028 0.0048 0.0047
Echinococcus granulosus u4:u6.u5 tri snrnp associated protein 2 0.0015 0.001 0.0024
Trichomonas vaginalis casein kinase II beta chain, putative 0.0038 0.0075 0.0474
Entamoeba histolytica hypothetical protein 0.0039 0.0078 0.0492
Mycobacterium ulcerans acyl-CoA synthetase 0.0028 0.0048 0.0044
Echinococcus granulosus SNF4:AMP activated protein kinase gamma subunit 0.0021 0.0025 0.006
Trypanosoma cruzi Casein kinase II subunit beta, putative 0.0038 0.0075 0.0388

Activities

Activity type Activity value Assay description Source Reference
CT10 (functional) = 860 uM h Cytotoxicity under aerobic conditions determined to reduce the AA8 cell survival to 10% controls in clonogenic assay ChEMBL. 9135035
IC50 (functional) = 18 uM Growth inhibition of aerobic AA8 cells, after 18 hours exposure ChEMBL. 9135035
pKa (ADMET) = 6.78 Affinity constant determined in aqueous solution ChEMBL. 9135035
Ratio (functional) = 10 Hypoxic selectivity expressed as cytotoxic ratio of CT10 (air) / CT10 (nitrogen) in clonogenic assay ChEMBL. 9135035
Ratio (functional) = 11 Hypersensitivity factor ratio of IC50 (AA8)/IC50(UV4) for an 18 hours drug exposure under aerobic conditions. ChEMBL. 9135035

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
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External resources for this compound

Bibliographic References

1 literature reference was collected for this gene.

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