Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Echinococcus multilocularis | ecdysone induced protein 78C | 0.0112 | 0.6011 | 1 |
Brugia malayi | Nuclear hormone receptor family member nhr-19 | 0.0112 | 0.6011 | 1 |
Echinococcus multilocularis | nuclear receptor 2DBD gamma | 0.0112 | 0.6011 | 1 |
Brugia malayi | Nuclear hormone receptor family member nhr-41 | 0.0112 | 0.6011 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0112 | 0.6011 | 1 |
Plasmodium vivax | bifunctional dihydrofolate reductase-thymidylate synthase, putative | 0.0146 | 1 | 0.5 |
Trypanosoma brucei | dihydrofolate reductase-thymidylate synthase | 0.0146 | 1 | 0.5 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-41 | 0.0112 | 0.6011 | 1 |
Echinococcus multilocularis | Nuclear hormone receptor family member nhr 41 | 0.0112 | 0.6011 | 1 |
Schistosoma mansoni | retinoid-x-receptor (RXR) | 0.0112 | 0.6011 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0112 | 0.6011 | 1 |
Toxoplasma gondii | bifunctional dihydrofolate reductase-thymidylate synthase | 0.0146 | 1 | 0.5 |
Onchocerca volvulus | Steroid hormone receptor family member cnr14 homolog | 0.0112 | 0.6011 | 1 |
Schistosoma mansoni | thyroid hormone receptor | 0.0112 | 0.6011 | 1 |
Brugia malayi | steroid hormone receptor | 0.0112 | 0.6011 | 1 |
Brugia malayi | Nuclear hormone receptor family member nhr-19 | 0.0112 | 0.6011 | 1 |
Brugia malayi | Nuclear hormone receptor family member nhr-40 | 0.0112 | 0.6011 | 1 |
Echinococcus granulosus | FTZ F1 alpha | 0.0112 | 0.6011 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0112 | 0.6011 | 1 |
Echinococcus multilocularis | thyroid hormone receptor alpha | 0.0112 | 0.6011 | 1 |
Brugia malayi | photoreceptor-specific nuclear receptor | 0.0112 | 0.6011 | 1 |
Echinococcus granulosus | FTZ F1 nuclear receptor protein | 0.0112 | 0.6011 | 1 |
Brugia malayi | thymidylate synthase | 0.0104 | 0.5154 | 0.8574 |
Echinococcus multilocularis | COUP TF:Svp nuclear hormone receptor | 0.0112 | 0.6011 | 1 |
Schistosoma mansoni | bifunctional dihydrofolate reductase-thymidylate synthase | 0.0104 | 0.5154 | 0.8574 |
Schistosoma mansoni | thyroid hormone receptor | 0.0112 | 0.6011 | 1 |
Schistosoma mansoni | retinoic acid receptor RXR | 0.0112 | 0.6011 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0112 | 0.6011 | 1 |
Onchocerca volvulus | 0.0112 | 0.6011 | 1 | |
Brugia malayi | Nuclear hormone receptor family member nhr-49 | 0.0112 | 0.6011 | 1 |
Brugia malayi | ecdysteroid receptor | 0.0112 | 0.6011 | 1 |
Echinococcus multilocularis | thymidylate synthase | 0.0104 | 0.5154 | 0.8574 |
Schistosoma mansoni | FTZ-F1 nuclear receptor-like protein | 0.0112 | 0.6011 | 1 |
Brugia malayi | Nuclear hormone receptor family member nhr-3 | 0.0112 | 0.6011 | 1 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-1 | 0.0112 | 0.6011 | 1 |
Loa Loa (eye worm) | steroid hormone receptor | 0.0112 | 0.6011 | 1 |
Brugia malayi | Ligand-binding domain of nuclear hormone receptor family protein | 0.0112 | 0.6011 | 1 |
Echinococcus granulosus | nuclear receptor 2DBD gamma | 0.0112 | 0.6011 | 1 |
Brugia malayi | Nuclear hormone receptor-like 1 | 0.0112 | 0.6011 | 1 |
Schistosoma mansoni | coup transcription factor | 0.0112 | 0.6011 | 1 |
Brugia malayi | Nuclear hormone receptor family member nhr-1 | 0.0112 | 0.6011 | 1 |
Echinococcus granulosus | ecdysone induced protein 78C | 0.0112 | 0.6011 | 1 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-14 | 0.0112 | 0.6011 | 1 |
Onchocerca volvulus | Protein ultraspiracle homolog | 0.0112 | 0.6011 | 1 |
Trypanosoma cruzi | dihydrofolate reductase-thymidylate synthase | 0.0146 | 1 | 0.5 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-49 | 0.0112 | 0.6011 | 1 |
Brugia malayi | Ligand-binding domain of nuclear hormone receptor family protein | 0.0112 | 0.6011 | 1 |
Echinococcus granulosus | hepatocyte nuclear factor 4 alpha | 0.0112 | 0.6011 | 1 |
Schistosoma mansoni | Tr4/Tr2 (homologue) | 0.0112 | 0.6011 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0112 | 0.6011 | 1 |
Schistosoma mansoni | RAR-like nuclear receptor | 0.0112 | 0.6011 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0112 | 0.6011 | 1 |
Echinococcus multilocularis | FTZ F1 nuclear receptor protein | 0.0112 | 0.6011 | 1 |
Loa Loa (eye worm) | thymidylate synthase | 0.0104 | 0.5154 | 0.8574 |
Schistosoma mansoni | nuclear hormone receptor | 0.0112 | 0.6011 | 1 |
Echinococcus granulosus | retinoic acid receptor rxr beta a | 0.0112 | 0.6011 | 1 |
Echinococcus granulosus | Nuclear hormone receptor family member nhr 41 | 0.0112 | 0.6011 | 1 |
Brugia malayi | Nuclear hormone receptor family member nhr-25 | 0.0112 | 0.6011 | 1 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-31 | 0.0112 | 0.6011 | 1 |
Brugia malayi | nuclear hormone receptor | 0.0112 | 0.6011 | 1 |
Echinococcus granulosus | thymidylate synthase | 0.0104 | 0.5154 | 0.8574 |
Mycobacterium leprae | PROBABLE THYMIDYLATE SYNTHASE THYA (TS) (TSASE) | 0.0104 | 0.5154 | 0.5 |
Schistosoma mansoni | nuclear receptor 2DBD-gamma | 0.0112 | 0.6011 | 1 |
Loa Loa (eye worm) | nuclear Hormone Receptor family member | 0.0112 | 0.6011 | 1 |
Echinococcus granulosus | COUP TF:Svp nuclear hormone receptor | 0.0112 | 0.6011 | 1 |
Brugia malayi | Nuclear hormone receptor family member nhr-14 | 0.0112 | 0.6011 | 1 |
Mycobacterium tuberculosis | Probable thymidylate synthase ThyA (ts) (TSASE) | 0.0104 | 0.5154 | 0.5 |
Echinococcus granulosus | nuclear receptor 2DBD gamma | 0.0112 | 0.6011 | 1 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-40 | 0.0112 | 0.6011 | 1 |
Schistosoma mansoni | steroid hormone receptor ad4bp | 0.0112 | 0.6011 | 1 |
Mycobacterium ulcerans | thymidylate synthase | 0.0104 | 0.5154 | 0.5 |
Brugia malayi | nuclear receptor NHR-88 | 0.0112 | 0.6011 | 1 |
Brugia malayi | Nuclear hormone receptor family member nhr-31 | 0.0112 | 0.6011 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0112 | 0.6011 | 1 |
Brugia malayi | Steroid receptor seven-up type 2 | 0.0112 | 0.6011 | 1 |
Plasmodium falciparum | bifunctional dihydrofolate reductase-thymidylate synthase | 0.0146 | 1 | 0.5 |
Echinococcus multilocularis | hepatocyte nuclear factor 4 alpha | 0.0112 | 0.6011 | 1 |
Echinococcus multilocularis | nuclear receptor 2DBD gamma | 0.0112 | 0.6011 | 1 |
Brugia malayi | Nuclear hormone receptor family member nhr-25 | 0.0112 | 0.6011 | 1 |
Schistosoma mansoni | photoreceptor-specific nuclear receptor related | 0.0112 | 0.6011 | 1 |
Onchocerca volvulus | Bile acid receptor homolog | 0.0112 | 0.6011 | 1 |
Schistosoma mansoni | nuclear hormone receptor nor-1/nor-2 | 0.0112 | 0.6011 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0112 | 0.6011 | 1 |
Echinococcus multilocularis | FTZ F1 alpha | 0.0112 | 0.6011 | 1 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.
1 literature reference was collected for this gene.