Detailed information for compound 39208

Basic information

Technical information
  • Name: Unnamed compound
  • MW: 314.526 | Formula: C18H34O2S
  • H donors: 1 H acceptors: 2 LogP: 6.93 Rotable bonds: 15
    Rule of 5 violations (Lipinski): 1
  • SMILES: CCCCCC1SC1CCCCCCCCCCC(=O)O
  • InChi: 1S/C18H34O2S/c1-2-3-10-13-16-17(21-16)14-11-8-6-4-5-7-9-12-15-18(19)20/h16-17H,2-15H2,1H3,(H,19,20)
  • InChiKey: FPRPYFYCJCNHRO-UHFFFAOYSA-N  


Substructure search Similarity search

Network

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Synonyms

No synonyms found for this compound

Targets

Known targets for this compound

Species Target name Source Bibliographic reference
Glycine max Seed lipoxygenase-1 Starlite/ChEMBL No references

Predicted pathogen targets for this compound

By orthology
Species Potential target Known druggable target/s Ortholog Group
Echinococcus multilocularis arachidonate 5 lipoxygenase Get druggable targets OG5_127482 All targets in OG5_127482
Echinococcus granulosus arachidonate 5 lipoxygenase Get druggable targets OG5_127482 All targets in OG5_127482
Schistosoma mansoni lipoxygenase Get druggable targets OG5_127482 All targets in OG5_127482
Schistosoma japonicum ko:K00461 arachidonate 5-lipoxygenase [EC1.13.11.34], putative Get druggable targets OG5_127482 All targets in OG5_127482
Schistosoma mansoni lipoxygenase Get druggable targets OG5_127482 All targets in OG5_127482
Schistosoma japonicum IPR001024,Lipoxygenase, LH2;IPR013819,Lipoxygenase, C-terminal,domain-containing Get druggable targets OG5_127482 All targets in OG5_127482
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Loa Loa (eye worm) hypothetical protein 0.0045 0.0031 0.0031
Entamoeba histolytica hypothetical protein 0.0026 0.0011 0.0095
Echinococcus multilocularis para nitrobenzyl esterase 0.159 0.1676 0.1676
Echinococcus multilocularis regulator of G protein signaling 3 0.0026 0.0011 0.0011
Entamoeba histolytica hypothetical protein 0.0026 0.0011 0.0095
Loa Loa (eye worm) hypothetical protein 0.0021 0.0005 0.0005
Toxoplasma gondii AGC kinase 0.0029 0.0014 0.1165
Loa Loa (eye worm) hypothetical protein 0.0101 0.0091 0.0091
Onchocerca volvulus 0.159 0.1676 1
Echinococcus granulosus gamma aminobutyric acid receptor subunit 0.0021 0.0005 0.0005
Echinococcus multilocularis ribosomal protein S6 kinase alpha 3 0.0191 0.0187 0.0187
Echinococcus multilocularis lysine specific demethylase 5A 0.0062 0.005 0.0049
Chlamydia trachomatis fructose-6-phosphate phosphotransferase 0.003 0.0016 1
Trichomonas vaginalis phosphofructokinase, putative 0.0111 0.0102 0.0583
Trichomonas vaginalis AGC family protein kinase 0.0029 0.0014 0.0056
Echinococcus granulosus serine:threonine protein kinase:endoribonuclease 0.0308 0.0311 0.0311
Brugia malayi hypothetical protein 0.0017 0.0002 0.0002
Brugia malayi Neurotransmitter-gated ion-channel ligand binding domain containing protein 0.0045 0.0031 0.0031
Leishmania major isocitrate dehydrogenase [NADP], mitochondrial precursor, putative 0.0017 0.0002 0.0042
Trichomonas vaginalis nicotinate phosphoribosyltransferase, putative 0.0155 0.0149 0.0861
Loa Loa (eye worm) AGC/RSK/P70 protein kinase 0.0029 0.0014 0.0014
Brugia malayi hypothetical protein 0.0021 0.0005 0.0005
Schistosoma mansoni hypothetical protein 0.0042 0.0028 0.0028
Echinococcus granulosus intermediate filament protein 0.0029 0.0015 0.0015
Echinococcus granulosus 6 phosphofructokinase 0.0111 0.0102 0.0102
Loa Loa (eye worm) cytochrome P450 family protein 0.003 0.0015 0.0015
Echinococcus granulosus aldehyde dehydrogenase mitochondrial 0.0128 0.012 0.012
Entamoeba histolytica pyrophosphate-dependent phosphofructokinase 0.003 0.0016 0.0169
Loa Loa (eye worm) pre-SET domain-containing protein family protein 0.044 0.0451 0.0451
Loa Loa (eye worm) hypothetical protein 0.0053 0.004 0.004
Schistosoma mansoni atypical protein kinase C 0.0029 0.0014 0.0014
Echinococcus multilocularis gamma aminobutyric acid receptor subunit 0.0021 0.0005 0.0005
Trichomonas vaginalis AGC family protein kinase 0.0029 0.0014 0.0056
Trichomonas vaginalis glutathione reductase, putative 0.003 0.0015 0.0064
Brugia malayi Carboxylesterase family protein 0.9412 1 1
Trypanosoma cruzi PAB1-binding protein , putative 0.0027 0.0012 0.074
Trichomonas vaginalis phosphofructokinase, putative 0.0111 0.0102 0.0583
Schistosoma mansoni thyroid hormone receptor 0.0163 0.0157 0.0156
Onchocerca volvulus 0.159 0.1676 1
Echinococcus multilocularis acetylcholine receptor subunit beta 1 0.0045 0.0031 0.0031
Schistosoma mansoni nicotinate phosphoribosyltransferase 0.0155 0.0149 0.0148
Schistosoma mansoni nuclear hormone receptor 0.003 0.0015 0.0015
Echinococcus multilocularis sterol regulatory element binding protein 0.0043 0.003 0.0029
Chlamydia trachomatis fructose-6-phosphate phosphotransferase 0.003 0.0016 1
Loa Loa (eye worm) hypothetical protein 0.0242 0.0241 0.0241
Echinococcus granulosus neuroligin 0.159 0.1676 0.1676
Echinococcus multilocularis lysosomal alpha glucosidase 0.0165 0.0159 0.0159
Brugia malayi hypothetical protein 0.0027 0.0012 0.0012
Schistosoma mansoni intermediate filament proteins 0.0029 0.0015 0.0015
Loa Loa (eye worm) hypothetical protein 0.0017 0.0001 0.0001
Leishmania major ATP-dependent phosphofructokinase 0.0111 0.0102 0.643
Schistosoma mansoni hypothetical protein 0.0049 0.0036 0.0036
Schistosoma mansoni nuclear hormone receptor nor-1/nor-2 0.003 0.0015 0.0015
Loa Loa (eye worm) glycosyl hydrolase family 31 protein 0.0037 0.0022 0.0022
Trichomonas vaginalis glutaminase, putative 0.0297 0.03 0.1767
Echinococcus multilocularis regulator of G protein signaling 0.0026 0.0011 0.0011
Schistosoma mansoni serine/threonine protein kinase 0.0043 0.0029 0.0029
Echinococcus multilocularis COUP TF:Svp nuclear hormone receptor 0.003 0.0015 0.0015
Loa Loa (eye worm) hypothetical protein 0.0325 0.033 0.0329
Echinococcus granulosus acetylcholine receptor subunit beta 1 0.0045 0.0031 0.0031
Giardia lamblia Fructose-bisphosphate aldolase 0.0627 0.065 1
Brugia malayi Neurotransmitter-gated ion-channel transmembrane region family protein 0.0045 0.0031 0.0031
Brugia malayi Nuclear hormone receptor family member nhr-1 0.003 0.0015 0.0015
Trichomonas vaginalis AGC family protein kinase 0.0029 0.0014 0.0056
Loa Loa (eye worm) isocitrate dehydrogenase 0.0017 0.0002 0.0002
Trypanosoma brucei dihydrolipoamide dehydrogenase 0.003 0.0015 0.0962
Loa Loa (eye worm) glutaminase 2 0.0297 0.03 0.03
Brugia malayi acetylcholine receptor alpha subunit precursor, putative 0.0045 0.0031 0.0031
Trypanosoma brucei glucosidase, putative 0.0037 0.0022 0.1442
Echinococcus granulosus expressed conserved protein 0.0095 0.0084 0.0084
Schistosoma mansoni rab6-interacting 0.0024 0.0009 0.0009
Leishmania major acetoin dehydrogenase e3 component-like protein 0.003 0.0015 0.0903
Trichomonas vaginalis conserved hypothetical protein 0.0157 0.015 0.087
Mycobacterium leprae Probable fructose bisphosphate aldolase Fba 0.0306 0.0309 1
Loa Loa (eye worm) 6-phosphofructokinase 0.0111 0.0102 0.0102
Schistosoma mansoni hypothetical protein 0.0024 0.0009 0.0009
Mycobacterium tuberculosis Probable fructose-bisphosphate aldolase Fba 0.0306 0.0309 0.1837
Echinococcus granulosus jumonji domain containing 1A 0.0017 0.0001 0.0001
Brugia malayi jmjC domain containing protein 0.0062 0.005 0.0049
Loa Loa (eye worm) RGS-3 protein 0.0026 0.0011 0.0011
Echinococcus multilocularis Transcription factor, JmjC domain containing protein 0.0062 0.005 0.0049
Schistosoma mansoni protein phosphatase 2C 0.0017 0.0001 0.0001
Brugia malayi hypothetical protein 0.0242 0.0241 0.0241
Treponema pallidum fructose-bisphosphate aldolase 0.0627 0.065 1
Toxoplasma gondii histone lysine acetyltransferase GCN5-A 0.0043 0.0029 0.2402
Loa Loa (eye worm) hypothetical protein 0.0021 0.0005 0.0005
Onchocerca volvulus 0.159 0.1676 1
Schistosoma mansoni alpha glucosidase 0.0037 0.0022 0.0022
Trichomonas vaginalis alpha-glucosidase, putative 0.0037 0.0022 0.0106
Brugia malayi Niemann-Pick C1 protein precursor 0.0101 0.0091 0.0091
Brugia malayi Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain containing protein 0.0022 0.0007 0.0007
Brugia malayi hypothetical protein 0.0302 0.0305 0.0305
Echinococcus multilocularis nicotinic acetylcholine receptor a11 subunit 0.0045 0.0031 0.0031
Trypanosoma cruzi trypanothione reductase, putative 0.0086 0.0075 0.5033
Schistosoma mansoni serine/threonine protein kinase 0.0029 0.0014 0.0014
Loa Loa (eye worm) glutamate-gated chloride channel alpha3A subunit 0.0045 0.0031 0.0031
Schistosoma mansoni nAChR subunit (ShAR1-beta2-like) 0.0045 0.0031 0.0031
Schistosoma mansoni nAChR subunit (ShAR1-alpha-like) 0.0188 0.0184 0.0184
Echinococcus multilocularis protein kinase c iota type 0.0029 0.0014 0.0014
Echinococcus multilocularis lamin dm0 0.0029 0.0015 0.0015
Trichomonas vaginalis alpha-glucosidase, putative 0.0037 0.0022 0.0106
Schistosoma mansoni Cys-loop ligand gated ion channel subunit 0.0045 0.0031 0.0031
Schistosoma mansoni FTZ-F1 nuclear receptor-like protein 0.003 0.0015 0.0015
Loa Loa (eye worm) jmjC domain-containing protein 0.0062 0.005 0.0049
Echinococcus multilocularis lamin 0.0029 0.0015 0.0015
Trypanosoma cruzi trypanothione reductase, putative 0.003 0.0015 0.0962
Brugia malayi Acetylcholine receptor protein, alpha-like chain 1 precursor 0.0021 0.0005 0.0005
Loa Loa (eye worm) nuclear hormone receptor family member nhr-40 0.003 0.0015 0.0015
Echinococcus granulosus neutral alpha glucosidase AB 0.0037 0.0022 0.0022
Schistosoma mansoni lipoxygenase 0.01 0.0089 0.0089
Schistosoma mansoni NADP-specific isocitrate dehydrogenase 0.0017 0.0002 0.0002
Onchocerca volvulus 0.0029 0.0015 0.0056
Loa Loa (eye worm) hypothetical protein 0.0188 0.0184 0.0184
Loa Loa (eye worm) hypothetical protein 0.0026 0.0011 0.0011
Schistosoma mansoni ubiquitously transcribed sex (X/Y) chromosome tetratricopeptide repeat protein-related 0.0017 0.0001 0.0001
Echinococcus multilocularis serine:threonine protein kinase:endoribonuclease 0.0308 0.0311 0.0311
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0627 0.065 0.3864
Brugia malayi PAS domain containing protein 0.0053 0.004 0.004
Loa Loa (eye worm) IRE protein kinase 0.0308 0.0311 0.0311
Plasmodium falciparum ADP-dependent DNA helicase RecQ 0.002 0.0005 0.0276
Echinococcus multilocularis NADP dependent isocitrate dehydrogenase 0.0017 0.0002 0.0002
Schistosoma mansoni dihydrolipoamide dehydrogenase 0.003 0.0015 0.0015
Schistosoma mansoni aldehyde dehydrogenase 0.0128 0.012 0.012
Brugia malayi Neurotransmitter-gated ion-channel ligand binding domain containing protein 0.0045 0.0031 0.0031
Echinococcus granulosus single minded 2 0.0039 0.0025 0.0025
Brugia malayi bHLH-PAS transcription factor 0.0039 0.0025 0.0025
Trichomonas vaginalis AGC family protein kinase 0.0029 0.0014 0.0056
Brugia malayi glutaminase DH11.1 0.0297 0.03 0.03
Brugia malayi dihydrolipoyl dehydrogenase, mitochondrial precursor, putative 0.003 0.0015 0.0015
Schistosoma mansoni alpha-glucosidase 0.0142 0.0134 0.0134
Trichomonas vaginalis phosphofructokinase, putative 0.003 0.0016 0.0065
Loa Loa (eye worm) hypothetical protein 0.0021 0.0005 0.0005
Echinococcus multilocularis arachidonate 5 lipoxygenase 0.0142 0.0135 0.0135
Schistosoma mansoni family S9 non-peptidase homologue (S09 family) 0.9412 1 1
Loa Loa (eye worm) hypothetical protein 0.0045 0.0031 0.0031
Brugia malayi steroid hormone receptor 0.003 0.0015 0.0015
Trypanosoma brucei nicotinate phosphoribosyltransferase, putative 0.0155 0.0149 1
Loa Loa (eye worm) hypothetical protein 0.003 0.0015 0.0015
Schistosoma mansoni family S9 non-peptidase homologue (S09 family) 0.159 0.1676 0.1676
Mycobacterium ulcerans flavoprotein disulfide reductase 0.003 0.0015 0.0064
Echinococcus multilocularis expressed protein 0.0411 0.0421 0.0421
Schistosoma mansoni nicotinate phosphoribosyltransferase related pre-B cell enhancing factor 0.0155 0.0149 0.0148
Echinococcus granulosus Polycystic kidney disease protein 0.0024 0.0009 0.0009
Echinococcus granulosus regulator of G protein signaling 3 0.0026 0.0011 0.0011
Toxoplasma gondii 6-phosphofructokinase 0.003 0.0016 0.1294
Schistosoma mansoni neurotransmitter gated ion channel 0.0021 0.0005 0.0005
Echinococcus multilocularis acetylcholinesterase 0.9412 1 1
Leishmania major apurinic/apyrimidinic endonuclease-redox protein 0.002 0.0005 0.0224
Onchocerca volvulus 0.0024 0.0009 0.0022
Trichomonas vaginalis carboxylesterase domain containing protein, putative 0.159 0.1676 1
Brugia malayi hypothetical protein 0.0125 0.0116 0.0116
Schistosoma mansoni nAChR subunit 0.0021 0.0005 0.0005
Brugia malayi hypothetical protein 0.0024 0.0009 0.0009
Entamoeba histolytica phosphofructokinase, putative 0.0111 0.0102 0.1509
Loa Loa (eye worm) acetylcholinesterase 1 0.9412 1 1
Brugia malayi Pre-SET motif family protein 0.044 0.0451 0.0451
Schistosoma mansoni neurotransmitter gated ion channel 0.0021 0.0005 0.0005
Echinococcus granulosus family S9 non peptidase ue S09 family 0.159 0.1676 0.1676
Echinococcus multilocularis survival motor neuron protein 1 0.0242 0.0241 0.0241
Loa Loa (eye worm) doublecortin family protein 0.0024 0.0009 0.0009
Trypanosoma brucei PAB1-binding protein , putative 0.0027 0.0012 0.074
Echinococcus granulosus bloom syndrome protein 0.0023 0.0008 0.0008
Wolbachia endosymbiont of Brugia malayi dihydrolipoamide dehydrogenase E3 component 0.003 0.0015 1
Echinococcus granulosus axis inhibition protein axin 0.0026 0.0011 0.0011
Brugia malayi Nuclear hormone receptor family member nhr-25 0.003 0.0015 0.0015
Mycobacterium tuberculosis Nicotinic acid phosphoribosyltransferase PncB2 0.0155 0.0149 0.0876
Schistosoma mansoni serine/threonine protein kinase 0.0027 0.0012 0.0012
Plasmodium vivax multidomain scavenger receptor, putative 0.0024 0.0009 0.115
Echinococcus multilocularis bloom syndrome protein 0.0023 0.0008 0.0008
Mycobacterium tuberculosis NAD(P)H quinone reductase LpdA 0.0219 0.0216 0.1281
Schistosoma mansoni lamin 0.0029 0.0015 0.0015
Loa Loa (eye worm) AGC/RSK/RSK protein kinase 0.0191 0.0187 0.0187
Schistosoma mansoni steroid hormone receptor ad4bp 0.003 0.0015 0.0015
Loa Loa (eye worm) hypothetical protein 0.0021 0.0005 0.0005
Trypanosoma cruzi dihydrolipoyl dehydrogenase, putative 0.003 0.0015 0.0962
Schistosoma mansoni acetylcholinesterase 0.159 0.1676 0.1676
Schistosoma mansoni Cys-loop ligand gated ion channel subunit 0.0045 0.0031 0.0031
Echinococcus granulosus beta-adrenergic receptor kinase 0.0027 0.0012 0.0012
Plasmodium falciparum ataxin-2 like protein, putative 0.0027 0.0012 0.074
Loa Loa (eye worm) hypothetical protein 0.0021 0.0005 0.0005
Plasmodium vivax isocitrate dehydrogenase [NADP], mitochondrial, putative 0.0017 0.0002 0.0211
Plasmodium falciparum thioredoxin reductase 0.0086 0.0075 0.5033
Loa Loa (eye worm) jmjC domain-containing protein 0.0017 0.0001 0.0001
Loa Loa (eye worm) hypothetical protein 0.0045 0.0031 0.0031
Leishmania major aldehyde dehydrogenase, mitochondrial precursor 0.0128 0.012 0.7573
Brugia malayi glutamate-gated chloride channel alpha3A subunit, putative 0.0024 0.0009 0.0009
Echinococcus granulosus Cys loop ligand gated ion channel subunit 0.0045 0.0031 0.0031
Mycobacterium tuberculosis holo-[acyl-carrier protein] synthase AcpS (holo-ACP synthase) (CoA:APO-[ACP]pantetheinephosphotransferase) (CoA:APO-[acyl-carrie 0.0025 0.001 0.0048
Echinococcus multilocularis Cys loop ligand gated ion channel subunit 0.0045 0.0031 0.0031
Brugia malayi Glycosyl hydrolases family 31 protein 0.0165 0.0159 0.0159
Onchocerca volvulus 0.0063 0.0051 0.027
Toxoplasma gondii 4'-phosphopantetheinyl transferase superfamily protein 0.0025 0.001 0.0816
Brugia malayi Neurotransmitter-gated ion-channel ligand binding domain containing protein 0.0045 0.0031 0.0031
Treponema pallidum diphosphate--fructose-6-phosphate 1-phosphotransferase 0.0111 0.0102 0.1509
Echinococcus granulosus acetylcholinesterase 0.9412 1 1
Mycobacterium tuberculosis Probable membrane NADH dehydrogenase NdhA 0.0197 0.0193 0.1142
Leishmania major dihydrolipoamide dehydrogenase, putative 0.003 0.0015 0.0903
Plasmodium falciparum glutathione reductase 0.0086 0.0075 0.5033
Schistosoma mansoni Cys-loop ligand gated ion channel subunit 0.0045 0.0031 0.0031
Entamoeba histolytica glycosyl hydrolase, family 31 protein 0.0037 0.0022 0.0275
Loa Loa (eye worm) AGC/AKT protein kinase 0.0029 0.0014 0.0014
Loa Loa (eye worm) hypothetical protein 0.0024 0.0009 0.0009
Loa Loa (eye worm) thioredoxin reductase 0.0086 0.0075 0.0075
Echinococcus granulosus nicotinic acetylcholine receptor subunit alpha 8 0.0045 0.0031 0.0031
Schistosoma mansoni jumonji/arid domain-containing protein 0.0062 0.005 0.0049
Echinococcus multilocularis expressed conserved protein 0.0095 0.0084 0.0084
Mycobacterium tuberculosis Probable aldehyde dehydrogenase 0.0128 0.012 0.0706
Echinococcus multilocularis protein patched 0.0043 0.003 0.0029
Echinococcus granulosus para nitrobenzyl esterase 0.159 0.1676 0.1676
Schistosoma mansoni jumonji domain containing protein 0.0062 0.005 0.0049
Brugia malayi photoreceptor-specific nuclear receptor 0.003 0.0015 0.0015
Brugia malayi ecdysteroid receptor 0.003 0.0015 0.0015
Mycobacterium tuberculosis Probable dehydrogenase 0.0197 0.0193 0.1142
Loa Loa (eye worm) nuclear hormone receptor family member nhr-1 0.003 0.0015 0.0015
Brugia malayi hypothetical protein 0.0026 0.0011 0.0011
Echinococcus granulosus nAChR subunit 0.0024 0.0009 0.0009
Echinococcus granulosus histone acetyltransferase KAT2B 0.0141 0.0133 0.0133
Loa Loa (eye worm) nuclear hormone receptor family member nhr-41 0.003 0.0015 0.0015
Brugia malayi Carboxylesterase family protein 0.159 0.1676 0.1676
Mycobacterium tuberculosis Probable reductase 0.0197 0.0193 0.1142
Echinococcus multilocularis serine:threonine protein kinase 38 0.0029 0.0014 0.0014
Plasmodium falciparum glutathione reductase 0.003 0.0015 0.0962
Brugia malayi A-kinase anchor protein 10, precursor 0.0026 0.0011 0.0011
Loa Loa (eye worm) hypothetical protein 0.0178 0.0172 0.0172
Toxoplasma gondii histone lysine acetyltransferase GCN5-B 0.0043 0.0029 0.2402
Trichomonas vaginalis set domain proteins, putative 0.05 0.0516 0.306
Schistosoma mansoni hypothetical protein 0.0042 0.0028 0.0028
Brugia malayi Nuclear hormone receptor family member nhr-14 0.003 0.0015 0.0015
Brugia malayi Neurotransmitter-gated ion-channel transmembrane region family protein 0.0024 0.0009 0.0009
Loa Loa (eye worm) hypothetical protein 0.0045 0.0031 0.0031
Toxoplasma gondii 4'-phosphopantetheinyl transferase domain-containing protein 0.0025 0.001 0.0816
Echinococcus multilocularis NADP dependent isocitrate dehydrogenase 0.0017 0.0002 0.0002
Brugia malayi Nuclear hormone receptor family member nhr-40 0.003 0.0015 0.0015
Loa Loa (eye worm) AGC/RSK/MSK protein kinase 0.0029 0.0014 0.0014
Brugia malayi Isocitrate dehydrogenase 0.0017 0.0002 0.0002
Echinococcus multilocularis lipoxygenase domain containing protein 0.0024 0.0009 0.0009
Onchocerca volvulus 0.0039 0.0025 0.0118
Brugia malayi aminoadipate-semialdehyde dehydrogenase-phosphopantetheinyl transferase 0.0088 0.0077 0.0077
Echinococcus multilocularis nicotinic acetylcholine receptor subunit type 0.0021 0.0005 0.0005
Loa Loa (eye worm) hypothetical protein 0.0021 0.0005 0.0005
Trichomonas vaginalis neutral alpha-glucosidase ab precursor, putative 0.0037 0.0022 0.0106
Trichomonas vaginalis sucrase-isomaltase, putative 0.0037 0.0022 0.0106
Trichomonas vaginalis conserved hypothetical protein 0.0026 0.0011 0.0037
Leishmania major dihydrolipoamide dehydrogenase, putative 0.003 0.0015 0.0903
Echinococcus granulosus regulator of G protein signaling 7 0.0026 0.0011 0.0011
Trichomonas vaginalis AGC family protein kinase 0.0029 0.0014 0.0056
Trypanosoma brucei apurinic/apyrimidinic endonuclease, putative 0.002 0.0005 0.0238
Loa Loa (eye worm) hypothetical protein 0.0021 0.0005 0.0005
Echinococcus granulosus nicotinic acetylcholine receptor alpha subunit 0.0045 0.0031 0.0031
Schistosoma mansoni serine/threonine protein kinase 0.0191 0.0187 0.0187
Schistosoma mansoni regulator of G protein signaling 3 rgs3 0.0026 0.0011 0.0011
Echinococcus granulosus BC026374 protein S09 family 0.159 0.1676 0.1676
Schistosoma mansoni z-protein (S1r protein) 0.0026 0.0011 0.0011
Echinococcus granulosus COUP TF:Svp nuclear hormone receptor 0.003 0.0015 0.0015
Brugia malayi hypothetical protein 0.0021 0.0005 0.0005
Loa Loa (eye worm) hypothetical protein 0.0021 0.0005 0.0005
Brugia malayi phosphofructokinase 0.0111 0.0102 0.0102
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0627 0.065 0.3864
Brugia malayi Glycosyl hydrolases family 31 protein 0.0037 0.0022 0.0022
Echinococcus granulosus nicotinic acetylcholine receptor a11 subunit 0.0045 0.0031 0.0031
Loa Loa (eye worm) hypothetical protein 0.003 0.0015 0.0015
Trichomonas vaginalis phosphofructokinase, putative 0.003 0.0016 0.0065
Brugia malayi Neurotransmitter-gated ion-channel ligand binding domain containing protein 0.0045 0.0031 0.0031
Echinococcus granulosus serine:threonine protein kinase N2 0.0029 0.0014 0.0014
Giardia lamblia Histone acetyltransferase GCN5 0.0039 0.0025 0.0316
Schistosoma mansoni Tr4/Tr2 (homologue) 0.003 0.0015 0.0015
Plasmodium falciparum holo-[acyl-carrier-protein] synthase, putative 0.0025 0.001 0.0587
Wolbachia endosymbiont of Brugia malayi dihydrolipoamide dehydrogenase E3 component 0.003 0.0015 1
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.003 0.0015 0.0962
Loa Loa (eye worm) hypothetical protein 0.9412 1 1
Brugia malayi nuclear hormone receptor 0.003 0.0015 0.0015
Mycobacterium ulcerans glutaminase 0.0297 0.03 0.1767
Loa Loa (eye worm) phosphofructokinase 0.0111 0.0102 0.0102
Brugia malayi Raf kinase 0.0043 0.0029 0.0029
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0627 0.065 0.3864
Mycobacterium tuberculosis POSSIBLE PARA-NITROBENZYL ESTERASE (FRAGMENT) 0.159 0.1676 1
Schistosoma mansoni ap endonuclease 0.002 0.0005 0.0005
Plasmodium vivax AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.002 0.0005 0.0592
Brugia malayi Regulator of G protein signaling domain containing protein 0.0026 0.0011 0.0011
Loa Loa (eye worm) AGC/DMPK/GEK protein kinase 0.0029 0.0014 0.0014
Trypanosoma cruzi apurinic/apyrimidinic endonuclease 0.002 0.0005 0.0238
Schistosoma mansoni gliotactin 0.159 0.1676 0.1676
Brugia malayi nicotinic acetylcholine receptor beta-1 chain precursor 0.0045 0.0031 0.0031
Entamoeba histolytica protein kinase, putative 0.0308 0.0311 0.4744
Loa Loa (eye worm) AGC/GRK/BARK protein kinase 0.0027 0.0012 0.0012
Loa Loa (eye worm) hypothetical protein 0.0045 0.0031 0.0031
Schistosoma mansoni serine/threonine protein kinase 0.0029 0.0014 0.0014
Brugia malayi Cation transporter family protein 0.0188 0.0184 0.0184
Loa Loa (eye worm) vesicular acetylcholine transporter unc-17 0.0219 0.0217 0.0216
Loa Loa (eye worm) AGC/PKN protein kinase 0.0029 0.0014 0.0014
Echinococcus multilocularis 6 phosphofructokinase 0.0111 0.0102 0.0102
Echinococcus granulosus protein kinase c epsilon type 0.0029 0.0014 0.0014
Echinococcus granulosus Niemann Pick C1 protein 0.0101 0.0091 0.0091
Mycobacterium tuberculosis Probable nitrite reductase [NAD(P)H] large subunit [FAD flavoprotein] NirB 0.0197 0.0193 0.1142
Echinococcus granulosus Regulator of G protein signaling 20 0.0026 0.0011 0.0011
Echinococcus multilocularis neuronal acetylcholine receptor subunit alpha 4 0.0045 0.0031 0.0031
Loa Loa (eye worm) nuclear hormone receptor family member nhr-49 0.003 0.0015 0.0015
Trichomonas vaginalis conserved hypothetical protein 0.0026 0.0011 0.0037
Schistosoma mansoni Cys-loop ligand gated ion channel subunit 0.0024 0.0009 0.0009
Onchocerca volvulus 0.0302 0.0305 0.1793
Schistosoma mansoni nAChR subunit (ShAR1-beta-like) 0.0188 0.0184 0.0184
Echinococcus granulosus nuclear receptor 2DBD gamma 0.003 0.0015 0.0015
Giardia lamblia Pyrophosphate-fructose 6-phosphate 1-phosphotransferase alpha subunit 0.003 0.0016 0.0169
Entamoeba histolytica protein kinase, putative 0.0308 0.0311 0.4744
Brugia malayi Neurotransmitter-gated ion-channel transmembrane region family protein 0.0045 0.0031 0.0031
Echinococcus granulosus FTZ F1 nuclear receptor protein 0.003 0.0015 0.0015
Loa Loa (eye worm) glutamate-gated chloride channel alpha3A subunit 0.0021 0.0005 0.0005
Brugia malayi Pre-B cell enhancing factor precursor 0.0836 0.0873 0.0873
Toxoplasma gondii LsmAD domain-containing protein 0.0027 0.0012 0.1002
Echinococcus granulosus arachidonate 5 lipoxygenase 0.0142 0.0135 0.0135
Brugia malayi exodeoxyribonuclease III family protein 0.002 0.0005 0.0005
Brugia malayi Protein kinase domain containing protein 0.0029 0.0014 0.0014
Schistosoma mansoni nAChR subunit 0.0045 0.0031 0.0031
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0627 0.065 0.3864
Loa Loa (eye worm) hypothetical protein 0.0024 0.0009 0.0009
Echinococcus multilocularis raf serine:threonine protein kinase 0.0043 0.0029 0.0029
Schistosoma mansoni acetylcholine receptor-related 0.0021 0.0005 0.0005
Trichomonas vaginalis maltase-glucoamylase, putative 0.0037 0.0022 0.0106
Brugia malayi Bloom's syndrome protein homolog 0.0023 0.0008 0.0008
Loa Loa (eye worm) hypothetical protein 0.9412 1 1
Treponema pallidum NADH oxidase 0.003 0.0015 0.0165
Trypanosoma cruzi PAB1-binding protein , putative 0.0027 0.0012 0.074
Entamoeba histolytica phosphofructokinase, putative 0.0111 0.0102 0.1509
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.003 0.0015 0.0015
Giardia lamblia NADH oxidase lateral transfer candidate 0.003 0.0015 0.0165
Echinococcus multilocularis A kinase anchor protein 10, mitochondrial 0.0026 0.0011 0.0011
Trypanosoma brucei hypothetical protein, conserved 0.0025 0.001 0.0587
Echinococcus granulosus glycine receptor subunit alpha 1 0.0045 0.0031 0.0031
Loa Loa (eye worm) jmjC domain-containing protein 0.0017 0.0001 0.0001
Echinococcus multilocularis glycine receptor subunit alpha 1 0.0045 0.0031 0.0031
Loa Loa (eye worm) 6-phosphofructokinase 0.0111 0.0102 0.0102
Onchocerca volvulus 0.0024 0.0009 0.002
Echinococcus multilocularis carboxylesterase 5A 0.9412 1 1
Toxoplasma gondii phosphofructokinase PFKII 0.003 0.0016 0.1294
Brugia malayi hypothetical protein 0.159 0.1676 0.1676
Brugia malayi 6-phosphofructokinase 0.0111 0.0102 0.0102
Loa Loa (eye worm) hypothetical protein 0.0045 0.0031 0.0031
Trypanosoma cruzi dihydrolipoyl dehydrogenase, putative 0.003 0.0015 0.0962
Echinococcus granulosus NADP dependent isocitrate dehydrogenase 0.0017 0.0002 0.0002
Onchocerca volvulus 0.0024 0.0009 0.0022
Loa Loa (eye worm) nuclear hormone receptor family member nhr-31 0.003 0.0015 0.0015
Brugia malayi ribosomal protein S6 kinase alpha 3 0.0164 0.0158 0.0158
Plasmodium vivax ataxin-2 like protein, putative 0.0027 0.0012 0.1576
Brugia malayi Hr1 repeat family protein 0.0029 0.0014 0.0014
Trichomonas vaginalis alpha-glucosidase, putative 0.0037 0.0022 0.0106
Mycobacterium tuberculosis POSSIBLE PARA-NITROBENZYL ESTERASE (FRAGMENT) 0.159 0.1676 1
Loa Loa (eye worm) hypothetical protein 0.0027 0.0012 0.0012
Echinococcus granulosus lipoxygenase domain containing protein 0.0024 0.0009 0.0009
Echinococcus multilocularis Niemann Pick C1 protein 0.0144 0.0137 0.0137
Loa Loa (eye worm) hypothetical protein 0.159 0.1676 0.1676
Echinococcus multilocularis regulator of G protein signaling 7 0.0026 0.0011 0.0011
Schistosoma mansoni nuclear receptor 2DBD-gamma 0.003 0.0015 0.0015
Plasmodium falciparum AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.002 0.0005 0.0238
Brugia malayi Nuclear hormone receptor family member nhr-19 0.003 0.0015 0.0015
Onchocerca volvulus 0.0029 0.0015 0.0056
Schistosoma mansoni vesicular acetylcholine transporter 0.0219 0.0217 0.0216
Schistosoma mansoni serine/threonine kinase 0.0029 0.0014 0.0014
Brugia malayi Thioredoxin reductase 0.0086 0.0075 0.0075
Trypanosoma cruzi nicotinate phosphoribosyltransferase, putative 0.0155 0.0149 1
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0627 0.065 0.3864
Brugia malayi jmjC domain containing protein 0.0017 0.0001 0.0001
Loa Loa (eye worm) hypothetical protein 0.0045 0.0031 0.0031
Leishmania major trypanothione reductase 0.0086 0.0075 0.4725
Schistosoma mansoni regulator of G protein signaling 0.0026 0.0011 0.0011
Brugia malayi hypothetical protein 0.0021 0.0005 0.0005
Loa Loa (eye worm) hypothetical protein 0.0024 0.0009 0.0009
Echinococcus granulosus A kinase anchor protein 10 mitochondrial 0.0026 0.0011 0.0011
Loa Loa (eye worm) hypothetical protein 0.0045 0.0031 0.0031
Echinococcus multilocularis lipoxygenase domain containing protein 0.0024 0.0009 0.0009
Echinococcus multilocularis nicotinic acetylcholine receptor subunit alpha 8 0.0045 0.0031 0.0031
Schistosoma mansoni serine/threonine protein kinase 0.0027 0.0012 0.0012
Plasmodium vivax JmjC domain containing protein 0.0017 0.0001 0.0124
Leishmania major alpha glucosidase II subunit, putative 0.0037 0.0022 0.1354
Mycobacterium ulcerans fructose-bisphosphate aldolase 0.0306 0.0309 0.1823
Schistosoma mansoni histone-lysine n-methyltransferase suv9 0.0063 0.0051 0.005
Schistosoma mansoni serine/threonine protein kinase 0.0027 0.0012 0.0012
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0063 0.0051 0.005
Loa Loa (eye worm) G protein signaling regulator EGL-10 0.0026 0.0011 0.0011
Loa Loa (eye worm) intermediate filament protein 0.0029 0.0015 0.0015
Echinococcus granulosus lysine specific demethylase 5A 0.0062 0.005 0.0049
Brugia malayi Cation transporter family protein 0.0045 0.0031 0.0031
Brugia malayi intermediate filament protein 0.0029 0.0015 0.0015
Onchocerca volvulus Steroid hormone receptor family member cnr14 homolog 0.003 0.0015 0.0057
Entamoeba histolytica protein kinase, putative 0.0029 0.0014 0.0145
Echinococcus multilocularis L aminoadipate semialdehyde 0.0088 0.0077 0.0077
Toxoplasma gondii aldehyde dehydrogenase 0.0128 0.012 1
Loa Loa (eye worm) hypothetical protein 0.159 0.1676 0.1676
Brugia malayi cytoplasmic intermediate filament protein 0.0016 0 0.0000080251
Brugia malayi Neurotransmitter-gated ion-channel ligand binding domain containing protein 0.0021 0.0005 0.0005
Echinococcus granulosus nicotinic acetylcholine receptor subunit type 0.0045 0.0031 0.0031
Brugia malayi Neurotransmitter-gated ion-channel ligand binding domain containing protein 0.0021 0.0005 0.0005
Brugia malayi nuclear receptor NHR-88 0.003 0.0015 0.0015
Schistosoma mansoni coup transcription factor 0.003 0.0015 0.0015
Echinococcus multilocularis serine threonine protein kinase 0.0029 0.0014 0.0014
Echinococcus multilocularis protein kinase c epsilon type 0.0029 0.0014 0.0014
Loa Loa (eye worm) hypothetical protein 0.0026 0.0011 0.0011
Schistosoma mansoni phd/f-box containing protein 0.0017 0.0001 0.0001
Echinococcus granulosus ribosomal protein S6 kinase alpha 3 0.0191 0.0187 0.0187
Loa Loa (eye worm) nicotinic acetylcholine receptor alpha subunit 0.0045 0.0031 0.0031
Trichomonas vaginalis DNA helicase recq1, putative 0.0023 0.0008 0.0021
Trichomonas vaginalis bromodomain-containing protein, putative 0.0043 0.0029 0.0145
Echinococcus granulosus glycine receptor subunit alpha 1 0.0045 0.0031 0.0031
Loa Loa (eye worm) hypothetical protein 0.0045 0.0031 0.0031
Loa Loa (eye worm) ACC-1 protein 0.0045 0.0031 0.0031
Toxoplasma gondii pyruvate dehydrogenase complex subunit PDH-E3II 0.003 0.0015 0.1276
Schistosoma mansoni neuroligin 3 (S09 family) 0.159 0.1676 0.1676
Loa Loa (eye worm) ACC-1 protein 0.0045 0.0031 0.0031
Loa Loa (eye worm) hypothetical protein 0.0302 0.0305 0.0305
Onchocerca volvulus 0.05 0.0516 0.3057
Onchocerca volvulus Protein ultraspiracle homolog 0.003 0.0015 0.0057
Plasmodium falciparum dihydrolipoyl dehydrogenase, mitochondrial 0.003 0.0015 0.0962
Brugia malayi excitatory GABA receptor EXP-1A 0.0045 0.0031 0.0031
Trichomonas vaginalis regulator of G protein signaling 5, rgs5, putative 0.0026 0.0011 0.0037
Loa Loa (eye worm) hypothetical protein 0.003 0.0015 0.0015
Echinococcus multilocularis glycine receptor subunit alpha 1 0.0045 0.0031 0.0031
Brugia malayi Nuclear hormone receptor-like 1 0.003 0.0015 0.0015
Brugia malayi 6-phosphofructokinase 0.0111 0.0102 0.0102
Schistosoma mansoni loxhd1 0.0024 0.0009 0.0009
Echinococcus multilocularis thyroid hormone receptor alpha 0.0163 0.0157 0.0156
Mycobacterium tuberculosis Putative ferredoxin reductase 0.0197 0.0193 0.1142
Plasmodium vivax glutathione reductase, putative 0.0086 0.0075 1
Brugia malayi CHE-14 protein 0.0043 0.003 0.0029
Loa Loa (eye worm) hypothetical protein 0.003 0.0015 0.0015
Trichomonas vaginalis DNA helicase recq, putative 0.0023 0.0008 0.0021
Echinococcus multilocularis axis inhibition protein axin 0.0026 0.0011 0.0011
Schistosoma mansoni blooms syndrome DNA helicase 0.0018 0.0003 0.0003
Entamoeba histolytica phosphofructokinase, putative 0.0111 0.0102 0.1509
Loa Loa (eye worm) AGC/NDR protein kinase 0.0029 0.0014 0.0014
Schistosoma mansoni retinoic acid receptor RXR 0.003 0.0015 0.0015
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0627 0.065 0.3864
Schistosoma mansoni gcn5proteinral control of amino-acid synthesis 5-like 2 gcnl2 0.0145 0.0138 0.0138
Plasmodium falciparum ATP-dependent 6-phosphofructokinase 0.003 0.0016 0.0977
Echinococcus granulosus hepatocyte nuclear factor 4 alpha 0.003 0.0015 0.0015
Schistosoma mansoni nAChR subunit 0.0045 0.0031 0.0031
Schistosoma mansoni single-minded 0.0053 0.004 0.004
Schistosoma mansoni regulator of G protein signaling 0.0026 0.0011 0.0011
Loa Loa (eye worm) hypothetical protein 0.159 0.1676 0.1676
Brugia malayi acetylcholine receptor, alpha-type subunit unc-38 precursor 0.0045 0.0031 0.0031
Loa Loa (eye worm) hypothetical protein 0.0024 0.0009 0.0009
Schistosoma mansoni serine/threonine protein kinase 0.0029 0.0014 0.0014
Brugia malayi jmjC domain containing protein 0.0017 0.0001 0.0001
Echinococcus multilocularis isocitrate dehydrogenase 0.0017 0.0002 0.0002
Echinococcus granulosus protein kinase C gamma type 0.0029 0.0014 0.0014
Loa Loa (eye worm) excitatory GABA receptor EXP-1A 0.0045 0.0031 0.0031
Loa Loa (eye worm) PXA domain-containing protein 0.0026 0.0011 0.0011
Echinococcus granulosus regulator of G protein signaling 3 0.0026 0.0011 0.0011
Loa Loa (eye worm) hypothetical protein 0.0063 0.0051 0.005
Schistosoma mansoni nicotinic acetylcholine receptor alpha 0.0024 0.0009 0.0009
Trichomonas vaginalis alpha-glucosidase, putative 0.0037 0.0022 0.0106
Trypanosoma brucei dihydrolipoyl dehydrogenase 0.003 0.0015 0.0962
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0627 0.065 0.3864
Toxoplasma gondii glycosyl hydrolase, family 31 protein 0.0037 0.0022 0.1866
Loa Loa (eye worm) hypothetical protein 0.0026 0.0011 0.0011
Loa Loa (eye worm) carboxylesterase 0.9412 1 1
Echinococcus multilocularis Nuclear hormone receptor family member nhr 41 0.003 0.0015 0.0015
Brugia malayi Nuclear hormone receptor family member nhr-31 0.003 0.0015 0.0015
Brugia malayi protein kinase C II. 0.0029 0.0014 0.0014
Loa Loa (eye worm) pre-B cell enhancing factor 0.0836 0.0873 0.0873
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.003 0.0015 0.0015
Trypanosoma cruzi isocitrate dehydrogenase [NADP], mitochondrial precursor, putative 0.0017 0.0002 0.0044
Trichomonas vaginalis mercuric reductase, putative 0.003 0.0015 0.0064
Loa Loa (eye worm) hypothetical protein 0.159 0.1676 0.1676
Schistosoma mansoni hypothetical protein 0.0042 0.0028 0.0028
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.003 0.0015 0.0015
Schistosoma mansoni nAChR subunit 0.0045 0.0031 0.0031
Schistosoma mansoni thyroid hormone receptor 0.0163 0.0157 0.0156
Echinococcus multilocularis Jumonji, AT rich interactive domain 1B 0.0017 0.0001 0.0001
Plasmodium vivax thioredoxin reductase, putative 0.0086 0.0075 1
Echinococcus multilocularis DNA (apurinic or apyrimidinic site) lyase 0.002 0.0005 0.0005
Plasmodium vivax histone acetyltransferase GCN5, putative 0.0043 0.0029 0.3811
Echinococcus multilocularis nAChR subunit 0.0024 0.0009 0.0009
Echinococcus multilocularis serine:threonine protein kinase N2 0.0029 0.0014 0.0014
Echinococcus multilocularis aldehyde dehydrogenase, mitochondrial 0.0128 0.012 0.012
Trichomonas vaginalis AGC family protein kinase 0.0029 0.0014 0.0056
Schistosoma mansoni regulator of G protein signaling 17 19 20 (rgs17 19 20) 0.0026 0.0011 0.0011
Brugia malayi hypothetical protein 0.0026 0.0011 0.0011
Loa Loa (eye worm) hypothetical protein 0.0021 0.0005 0.0005
Schistosoma mansoni serine/threonine protein kinase 0.0029 0.0014 0.0014
Brugia malayi acetyltransferase, GNAT family protein 0.0145 0.0138 0.0138
Plasmodium falciparum histone acetyltransferase GCN5 0.0039 0.0025 0.1623
Plasmodium falciparum ATP-dependent 6-phosphofructokinase 0.003 0.0016 0.0977
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.003 0.0015 0.0962
Schistosoma mansoni hypothetical protein 0.0133 0.0125 0.0125
Giardia lamblia Kinase, AGC AKT 0.0164 0.0158 0.2377
Trypanosoma brucei dihydrolipoamide dehydrogenase, point mutation 0.003 0.0015 0.0962
Plasmodium falciparum ataxin-2 like protein, putative 0.0027 0.0012 0.074
Schistosoma mansoni rab6-interacting 0.0024 0.0009 0.0009
Brugia malayi Regulator of G protein signaling domain containing protein 0.0026 0.0011 0.0011
Echinococcus granulosus sterol regulatory element binding protein 0.0043 0.003 0.0029
Trichomonas vaginalis phosphofructokinase, putative 0.003 0.0016 0.0065
Echinococcus multilocularis gcn5proteinral control of amino acid synthesis 0.0145 0.0138 0.0138
Loa Loa (eye worm) hypothetical protein 0.0026 0.0011 0.0011
Loa Loa (eye worm) exodeoxyribonuclease III family protein 0.002 0.0005 0.0005
Plasmodium vivax SET domain protein, putative 0.0063 0.0051 0.6712
Schistosoma mansoni alpha-glucosidase 0.0142 0.0134 0.0134
Treponema pallidum 4'-phosphopantetheinyl transferase 0.0025 0.001 0.008
Plasmodium vivax dihydrolipoyl dehydrogenase, apicoplast, putative 0.003 0.0015 0.2012
Trichomonas vaginalis phosphofructokinase, putative 0.003 0.0016 0.0065
Brugia malayi Pre-SET motif family protein 0.0063 0.0051 0.005
Schistosoma mansoni family S9 non-peptidase homologue (S09 family) 0.159 0.1676 0.1676
Brugia malayi hypoxia-induced factor 1 0.0164 0.0158 0.0158
Echinococcus granulosus raf serine:threonine protein kinase 0.0043 0.0029 0.0029
Mycobacterium ulcerans carboxylesterase, LipT 0.159 0.1676 1
Trypanosoma cruzi hypothetical protein, conserved 0.0037 0.0022 0.1442
Schistosoma mansoni photoreceptor-specific nuclear receptor related 0.003 0.0015 0.0015
Onchocerca volvulus Vesicular acetylcholine transporter homolog 0.0219 0.0217 0.1264
Echinococcus multilocularis regulator of G protein signaling 7 0.0026 0.0011 0.0011
Brugia malayi nicotinic acetylcholine receptor alpha subunit, putative 0.0045 0.0031 0.0031
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0063 0.0051 0.005
Loa Loa (eye worm) hypothetical protein 0.0024 0.0009 0.0009
Loa Loa (eye worm) hypothetical protein 0.003 0.0015 0.0015
Echinococcus granulosus JmjC domain containing protein 4 0.0017 0.0001 0.0001
Brugia malayi Nuclear hormone receptor family member nhr-3 0.003 0.0015 0.0015
Onchocerca volvulus Bile acid receptor homolog 0.003 0.0015 0.0057
Echinococcus granulosus Ribosomal protein S6 kinase beta 2 0.0029 0.0014 0.0014
Trichomonas vaginalis conserved hypothetical protein 0.0026 0.0011 0.0037
Trichomonas vaginalis AGC family protein kinase 0.0029 0.0014 0.0056
Echinococcus granulosus acetylcholinesterase 0.9412 1 1
Echinococcus granulosus Protein patched homolog 1 0.0043 0.003 0.0029
Brugia malayi Steroid receptor seven-up type 2 0.003 0.0015 0.0015
Brugia malayi Carboxylesterase family protein 0.159 0.1676 0.1676
Schistosoma mansoni hypothetical protein 0.0042 0.0028 0.0028
Entamoeba histolytica hypothetical protein 0.0024 0.0009 0.0069
Mycobacterium ulcerans phosphopantetheinyl transferase, PptII 0.0025 0.001 0.0031
Brugia malayi Neurotransmitter-gated ion-channel ligand binding domain containing protein 0.0045 0.0031 0.0031
Loa Loa (eye worm) hypothetical protein 0.159 0.1676 0.1676
Echinococcus granulosus regulator of G protein signaling 7 0.0026 0.0011 0.0011
Chlamydia trachomatis dihydrolipoyl dehydrogenase 0.003 0.0015 0.9618
Echinococcus multilocularis Regulator of G protein signaling 20 0.0026 0.0011 0.0011
Trichomonas vaginalis AGC family protein kinase 0.0029 0.0014 0.0056
Echinococcus granulosus Nuclear hormone receptor family member nhr 41 0.003 0.0015 0.0015
Echinococcus multilocularis neuroligin 0.159 0.1676 0.1676
Onchocerca volvulus 0.0188 0.0184 0.1067
Brugia malayi Carboxylesterase family protein 0.159 0.1676 0.1676
Mycobacterium tuberculosis NADPH-dependent mycothiol reductase Mtr 0.0086 0.0075 0.0439
Mycobacterium leprae DIHYDROLIPOAMIDE DEHYDROGENASE LPD (LIPOAMIDE REDUCTASE (NADH)) (LIPOYL DEHYDROGENASE) (DIHYDROLIPOYL DEHYDROGENASE) (DIAPHORASE 0.0219 0.0216 0.6895
Brugia malayi Ribonuclease 2-5A family protein 0.0308 0.0311 0.0311
Loa Loa (eye worm) hypothetical protein 0.0045 0.0031 0.0031
Loa Loa (eye worm) hypothetical protein 0.0045 0.0031 0.0031
Echinococcus multilocularis protein dispatched 1 0.0049 0.0036 0.0036
Schistosoma mansoni survival motor neuron protein 0.0049 0.0036 0.0036
Loa Loa (eye worm) hypothetical protein 0.0024 0.0009 0.0009
Echinococcus multilocularis glycine receptor subunit beta 0.0045 0.0031 0.0031
Echinococcus multilocularis family S9 non peptidase ue (S09 family) 0.159 0.1676 0.1676
Loa Loa (eye worm) hypothetical protein 0.0045 0.0031 0.0031
Brugia malayi regulator of G-protein signaling egl-10 0.0026 0.0011 0.0011
Loa Loa (eye worm) hypothetical protein 0.0188 0.0184 0.0184
Brugia malayi p70 ribosomal S6 kinase beta 0.0029 0.0014 0.0014
Schistosoma mansoni hypothetical protein 0.0184 0.018 0.018
Mycobacterium ulcerans aldehyde dehydrogenase 0.0128 0.012 0.069
Loa Loa (eye worm) acetyltransferase 0.0145 0.0138 0.0138
Echinococcus multilocularis Mitotic checkpoint protein PRCC, C terminal 0.0133 0.0125 0.0125
Plasmodium vivax dihydrolipoyl dehydrogenase, mitochondrial, putative 0.003 0.0015 0.2012
Loa Loa (eye worm) hypothetical protein 0.0026 0.0011 0.0011
Schistosoma mansoni RAR-like nuclear receptor 0.003 0.0015 0.0015
Echinococcus granulosus histone acetyltransferase KAT2B 0.0043 0.0029 0.0029
Echinococcus granulosus Mitotic checkpoint protein PRCC C terminal 0.0133 0.0125 0.0125
Leishmania major phosphopantetheinyl transferase-like protein 0.0025 0.001 0.0551
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0627 0.065 0.3864
Echinococcus granulosus geminin 0.0184 0.018 0.018
Loa Loa (eye worm) hypothetical protein 0.0024 0.0009 0.0009
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.003 0.0015 0.0962
Echinococcus granulosus L aminoadipate semialdehyde 0.0088 0.0077 0.0077
Echinococcus multilocularis Polycystic kidney disease protein 0.0024 0.0009 0.0009
Entamoeba histolytica acetyltransferase, GNAT family 0.0039 0.0025 0.0316
Mycobacterium leprae PROBABLE 6-PHOSPHOFRUCTOKINASE PFKA (PHOSPHOHEXOKINASE) (PHOSPHOFRUCTOKINASE) 0.0111 0.0102 0.3081
Brugia malayi Protein kinase domain containing protein 0.0029 0.0014 0.0014
Schistosoma mansoni lamin 0.0029 0.0015 0.0015
Echinococcus multilocularis BC026374 protein (S09 family) 0.159 0.1676 0.1676
Entamoeba histolytica protein kinase, putative 0.0029 0.0014 0.0145
Echinococcus granulosus glycine receptor subunit beta 0.0045 0.0031 0.0031
Mycobacterium ulcerans putative regulatory protein 0.0039 0.0025 0.0123
Trypanosoma cruzi isocitrate dehydrogenase, putative 0.0017 0.0002 0.0044
Onchocerca volvulus Putative nachr subunit 0.0045 0.0031 0.0153
Loa Loa (eye worm) glycosyl hydrolase family 31 protein 0.0165 0.0159 0.0159
Echinococcus granulosus DNA apurinic or apyrimidinic site lyase 0.002 0.0005 0.0005
Loa Loa (eye worm) hypothetical protein 0.0088 0.0077 0.0077
Mycobacterium ulcerans 6-phosphofructokinase 0.0111 0.0102 0.0583
Echinococcus multilocularis RUN 0.0024 0.0009 0.0009
Schistosoma mansoni glutaminase 0.0297 0.03 0.03
Mycobacterium tuberculosis Probable NADH dehydrogenase Ndh 0.0197 0.0193 0.1142
Schistosoma mansoni nAChR subunit 0.0045 0.0031 0.0031
Brugia malayi hypothetical protein 0.0024 0.0009 0.0009
Brugia malayi Nuclear hormone receptor family member nhr-41 0.003 0.0015 0.0015
Echinococcus granulosus ribosomal protein s6 kinase beta 1 0.0029 0.0014 0.0014
Onchocerca volvulus 0.0045 0.0031 0.0153
Echinococcus multilocularis FTZ F1 nuclear receptor protein 0.003 0.0015 0.0015
Echinococcus granulosus Transcription factor JmjC domain containing protein 0.0062 0.005 0.0049
Schistosoma mansoni serine/threonine protein kinase 0.0158 0.0152 0.0152
Schistosoma mansoni neurotransmitter gated ion channel 0.0024 0.0009 0.0009
Brugia malayi hypothetical protein 0.0021 0.0005 0.0005
Brugia malayi regulator of G-protein signaling rgs-7 0.0026 0.0011 0.0011
Trypanosoma brucei dihydrolipoamide dehydrogenase 0.003 0.0015 0.0962
Echinococcus granulosus RUN 0.0024 0.0009 0.0009
Toxoplasma gondii phosphofructokinase domain-containing protein 0.003 0.0016 0.1294
Loa Loa (eye worm) hypothetical protein 0.0029 0.0015 0.0015
Echinococcus multilocularis geminin 0.0184 0.018 0.018
Plasmodium falciparum thioredoxin reductase 0.003 0.0015 0.0962
Echinococcus multilocularis transfer RNA-Lys 0.0039 0.0025 0.0025
Echinococcus granulosus NDR protein kinase 0.0029 0.0014 0.0014
Trichomonas vaginalis neutral alpha-glucosidase ab precursor, putative 0.0037 0.0022 0.0106
Echinococcus multilocularis ecdysone induced protein 78C 0.003 0.0015 0.0015
Mycobacterium tuberculosis Carboxylesterase LipT 0.159 0.1676 1
Trypanosoma cruzi ATP-dependent 6-phosphofructokinase, glycosomal 0.0111 0.0102 0.6849
Entamoeba histolytica hypothetical protein 0.0026 0.0011 0.0095
Echinococcus multilocularis Protein kinase C, brain isozyme 0.0029 0.0014 0.0014
Brugia malayi isocitrate dehydrogenase 0.0017 0.0002 0.0002
Schistosoma mansoni niemann-pick C1 (NPC1) 0.0102 0.0093 0.0092
Brugia malayi Doublecortin family protein 0.0024 0.0009 0.0009
Echinococcus multilocularis Cys loop ligand gated ion channel subunit 0.0021 0.0005 0.0005
Onchocerca volvulus 0.0045 0.0031 0.0153
Echinococcus multilocularis vesicular acetylcholine transporter 0.0219 0.0217 0.0216
Echinococcus multilocularis hepatocyte nuclear factor 4 alpha 0.003 0.0015 0.0015
Schistosoma mansoni hypothetical protein 0.0184 0.018 0.018
Plasmodium vivax 6-phosphofructokinase, putative 0.003 0.0016 0.2042
Echinococcus multilocularis JmjC domain containing protein 4 0.0017 0.0001 0.0001
Brugia malayi jmjC domain containing protein 0.0017 0.0001 0.0001
Echinococcus multilocularis dihydrolipoamide dehydrogenase 0.003 0.0015 0.0015
Loa Loa (eye worm) hypothetical protein 0.0021 0.0005 0.0005
Loa Loa (eye worm) hypothetical protein 0.0029 0.0014 0.0014
Echinococcus granulosus histone lysine methyltransferase setb 0.0063 0.0051 0.005
Loa Loa (eye worm) hypothetical protein 0.0024 0.0009 0.0009
Loa Loa (eye worm) abnormal chemotaxis protein 14 0.0043 0.003 0.0029
Schistosoma mansoni regulator of G protein signaling 0.0026 0.0011 0.0011
Loa Loa (eye worm) hypothetical protein 0.159 0.1676 0.1676
Trichomonas vaginalis AGC family protein kinase 0.0029 0.0014 0.0056
Leishmania major 2-oxoglutarate dehydrogenase, e3 component, lipoamidedehydrogenase-like protein 0.003 0.0015 0.0903
Schistosoma mansoni nAChR subunit 0.0045 0.0031 0.0031
Loa Loa (eye worm) steroid hormone receptor 0.003 0.0015 0.0015
Schistosoma mansoni aldehyde dehydrogenase 0.0128 0.012 0.012
Loa Loa (eye worm) GABA receptor subunit 0.0024 0.0009 0.0009
Schistosoma mansoni polycystin 1-related 0.0024 0.0009 0.0009
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0063 0.0051 0.005
Trichomonas vaginalis phosphofructokinase, putative 0.003 0.0016 0.0065
Trypanosoma cruzi apurinic/apyrimidinic endonuclease, putative 0.002 0.0005 0.0238
Loa Loa (eye worm) hypothetical protein 0.0021 0.0005 0.0005
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.003 0.0015 0.0962
Echinococcus multilocularis nAChR subunit 0.0045 0.0031 0.0031
Schistosoma mansoni lipoxygenase 0.0142 0.0135 0.0135
Brugia malayi Nuclear hormone receptor family member nhr-19 0.003 0.0015 0.0015
Loa Loa (eye worm) hypothetical protein 0.003 0.0015 0.0015
Schistosoma mansoni axis inhibition protein axin 0.0026 0.0011 0.0011
Echinococcus multilocularis isocitrate dehydrogenase 2 (NADP+) 0.0017 0.0002 0.0002
Echinococcus granulosus retinoic acid receptor rxr beta a 0.003 0.0015 0.0015
Entamoeba histolytica fructose-1,6-bisphosphate aldolase, putative 0.0627 0.065 1
Echinococcus multilocularis nicotinic acetylcholine receptor beta 1 subunit 0.0045 0.0031 0.0031
Trichomonas vaginalis conserved hypothetical protein 0.0026 0.0011 0.0037
Loa Loa (eye worm) hypothetical protein 0.0024 0.0009 0.0009
Trichomonas vaginalis conserved hypothetical protein 0.0043 0.003 0.0149
Loa Loa (eye worm) hypothetical protein 0.0045 0.0031 0.0031
Toxoplasma gondii thioredoxin reductase 0.0086 0.0075 0.6275
Brugia malayi Nuclear hormone receptor family member nhr-49 0.003 0.0015 0.0015
Schistosoma mansoni family S9 non-peptidase homologue (S09 family) 0.159 0.1676 0.1676
Brugia malayi Neurotransmitter-gated ion-channel transmembrane region family protein 0.0045 0.0031 0.0031
Entamoeba histolytica nicotinate phosphoribosyltransferase, putative 0.0155 0.0149 0.2228
Schistosoma mansoni aryl hydrocarbon receptor 0.0053 0.004 0.004
Echinococcus multilocularis histone lysine methyltransferase setb histone lysine methyltransferase eggless 0.0063 0.0051 0.005
Loa Loa (eye worm) hypothetical protein 0.0021 0.0005 0.0005
Schistosoma mansoni 6-phosphofructokinase 0.0111 0.0102 0.0102
Echinococcus granulosus lysine specific demethylase 6a 0.0017 0.0001 0.0001
Brugia malayi Intermediate filament tail domain containing protein 0.0029 0.0015 0.0015
Echinococcus granulosus glycine receptor subunit alpha 1 0.0045 0.0031 0.0031
Schistosoma mansoni serine/threonine protein kinase 0.0029 0.0014 0.0014
Mycobacterium ulcerans dihydrolipoamide dehydrogenase, LpdB 0.003 0.0015 0.0064
Loa Loa (eye worm) nuclear hormone receptor family member nhr-14 0.003 0.0015 0.0015
Mycobacterium tuberculosis Dihydrolipoamide dehydrogenase LpdC (lipoamide reductase (NADH)) (lipoyl dehydrogenase) (dihydrolipoyl dehydrogenase) (diaphoras 0.0219 0.0216 0.1281
Trypanosoma cruzi hypothetical protein, conserved 0.0037 0.0022 0.1442
Loa Loa (eye worm) hypothetical protein 0.0167 0.0162 0.0162
Loa Loa (eye worm) carboxylesterase 0.159 0.1676 0.1676
Echinococcus multilocularis regulator of G protein signaling 3 0.0026 0.0011 0.0011
Echinococcus granulosus axis inhibition protein axin 0.0026 0.0011 0.0011
Loa Loa (eye worm) nuclear Hormone Receptor family member 0.003 0.0015 0.0015
Trichomonas vaginalis spcc417.12 protein, putative 0.159 0.1676 1
Loa Loa (eye worm) hypothetical protein 0.0045 0.0031 0.0031
Echinococcus multilocularis axis inhibition protein axin 0.0026 0.0011 0.0011
Loa Loa (eye worm) jmjC domain-containing protein 0.0017 0.0001 0.0001
Echinococcus granulosus neuronal acetylcholine receptor subunit alpha 4 0.0045 0.0031 0.0031
Schistosoma mansoni serine/threonine protein kinase 0.0029 0.0014 0.0014
Onchocerca volvulus 0.0024 0.0009 0.002
Plasmodium vivax 6-phosphofructokinase, putative 0.003 0.0016 0.2042
Schistosoma mansoni patched 1 0.0043 0.003 0.0029
Echinococcus multilocularis atpase aaa+ type core atpase aaa type core 0.0829 0.0866 0.0866
Onchocerca volvulus 0.0095 0.0085 0.0476
Toxoplasma gondii histone lysine demethylase JMJC1/KDM5D/JARID1D 0.0017 0.0001 0.0094
Loa Loa (eye worm) AGC/PKC/ETA protein kinase 0.0029 0.0014 0.0014
Brugia malayi Neuronal acetylcholine receptor protein, alpha-2 chain precursor 0.0021 0.0005 0.0005
Trichomonas vaginalis alpha-glucosidase, putative 0.0037 0.0022 0.0106
Trypanosoma brucei ATP-dependent 6-phosphofructokinase, glycosomal 0.0111 0.0102 0.6849
Leishmania major rac serine-threonine kinase, putative,protein kinase, putative 0.0164 0.0158 1
Plasmodium falciparum dihydrolipoyl dehydrogenase, apicoplast 0.003 0.0015 0.0962
Echinococcus multilocularis serine:threonine protein kinase N2 0.0029 0.0014 0.0014
Mycobacterium ulcerans aldehyde dehydrogenase 0.0128 0.012 0.069
Trichomonas vaginalis conserved hypothetical protein 0.0026 0.0011 0.0037
Echinococcus multilocularis lysine specific demethylase 6a 0.0017 0.0001 0.0001
Schistosoma mansoni ap endonuclease 0.002 0.0005 0.0005
Loa Loa (eye worm) glutathione reductase 0.0086 0.0075 0.0075
Brugia malayi Hypothetical glycine receptor like protein T20B12.9 in chromosome III 0.0024 0.0009 0.0009
Brugia malayi Neurotransmitter-gated ion-channel transmembrane region family protein 0.0024 0.0009 0.0009
Echinococcus multilocularis NADP dependent isocitrate dehydrogenase 0.0017 0.0002 0.0002
Echinococcus granulosus nAChR subunit 0.0045 0.0031 0.0031
Schistosoma mansoni nAChR subunit 0.0021 0.0005 0.0005
Loa Loa (eye worm) raf kinase 0.0043 0.0029 0.0029
Echinococcus multilocularis Ribosomal protein S6 kinase beta 2 0.0029 0.0014 0.0014
Loa Loa (eye worm) neuronal acetylcholine receptor protein 0.0021 0.0005 0.0005
Echinococcus multilocularis lysosomal alpha glucosidase 0.0165 0.0159 0.0159
Echinococcus multilocularis beta adrenergic receptor kinase 0.0027 0.0012 0.0012
Brugia malayi vesicular acetylcholine transporter unc-17 0.0219 0.0217 0.0216
Loa Loa (eye worm) acetylcholine receptor alpha subunit 0.0045 0.0031 0.0031
Toxoplasma gondii NADPH-glutathione reductase 0.003 0.0015 0.1276
Toxoplasma gondii histone lysine methyltransferase SET/SUV39 0.0063 0.0051 0.4217
Toxoplasma gondii histone lysine demethylase JMJD6a 0.0017 0.0001 0.0094
Trypanosoma brucei isocitrate dehydrogenase [NADP], mitochondrial precursor, putative 0.0017 0.0002 0.0044
Echinococcus granulosus Protein kinase C brain isozyme 0.0029 0.0014 0.0014
Loa Loa (eye worm) LGC-31 protein 0.0045 0.0031 0.0031
Trichomonas vaginalis 6-phosphofructokinase, putative 0.003 0.0016 0.0065
Schistosoma mansoni regulator of G protein signaling 0.0026 0.0011 0.0011
Echinococcus multilocularis phd:f box containing protein 0.0017 0.0001 0.0001
Echinococcus granulosus dihydrolipoamide dehydrogenase 0.003 0.0015 0.0015
Echinococcus granulosus ecdysone induced protein 78C 0.003 0.0015 0.0015
Brugia malayi Nuclear hormone receptor family member nhr-25 0.003 0.0015 0.0015
Brugia malayi glutamate-gated chloride channel alpha3A subunit, putative 0.0021 0.0005 0.0005
Schistosoma mansoni retinoid-x-receptor (RXR) 0.003 0.0015 0.0015
Schistosoma mansoni nicotinate phosphoribosyltransferase related pre-B cell enhancing factor 0.0836 0.0873 0.0873
Echinococcus granulosus expressed protein 0.0411 0.0421 0.0421
Echinococcus granulosus survival motor neuron protein 1 0.0242 0.0241 0.0241
Brugia malayi gamma-aminobutyric-acid receptor beta subunit precursor 0.0045 0.0031 0.0031
Schistosoma mansoni aminoadipate-semialdehyde dehydrogenase 0.0088 0.0077 0.0077
Loa Loa (eye worm) acetylcholine receptor protein 0.0021 0.0005 0.0005
Loa Loa (eye worm) hypothetical protein 0.159 0.1676 0.1676
Echinococcus multilocularis histone lysine N methyltransferase SETMAR 0.0063 0.0051 0.005
Trypanosoma brucei isocitrate dehydrogenase, putative 0.0017 0.0002 0.0044
Onchocerca volvulus 0.0088 0.0077 0.0428
Echinococcus granulosus 5'partial|histone lysine N methyltransferase SETDB2 0.0061 0.0048 0.0048
Onchocerca volvulus 0.0049 0.0036 0.0184
Loa Loa (eye worm) hypothetical protein 0.0017 0.0001 0.0001
Loa Loa (eye worm) carboxylesterase 0.159 0.1676 0.1676
Brugia malayi PXA domain containing protein 0.0026 0.0011 0.0011
Toxoplasma gondii isocitrate dehydrogenase 0.0017 0.0002 0.0149
Echinococcus multilocularis acetylcholinesterase 0.9412 1 1
Loa Loa (eye worm) nicotinic acetylcholine receptor non-alpha subunit 0.0045 0.0031 0.0031
Echinococcus granulosus nuclear receptor 2DBD gamma 0.003 0.0015 0.0015
Loa Loa (eye worm) glutaminase 0.0297 0.03 0.03
Schistosoma mansoni regulator of G protein signaling 0.0027 0.0012 0.0012
Loa Loa (eye worm) hypothetical protein 0.0045 0.0031 0.0031
Plasmodium falciparum nicotinate phosphoribosyltransferase, putative 0.0155 0.0149 1
Leishmania major nicotinate phosphoribosyltransferase, putative 0.0155 0.0149 0.9388
Echinococcus granulosus FTZ F1 alpha 0.003 0.0015 0.0015
Trichomonas vaginalis phosphofructokinase, putative 0.003 0.0016 0.0065
Echinococcus granulosus glycine receptor subunit beta 0.0045 0.0031 0.0031
Loa Loa (eye worm) hypothetical protein 0.0021 0.0005 0.0005
Entamoeba histolytica glycosyl hydrolase, family 31 protein 0.0037 0.0022 0.0275
Echinococcus multilocularis glycine receptor subunit beta 0.0045 0.0031 0.0031
Mycobacterium ulcerans aldehyde dehydrogenase 0.0128 0.012 0.069
Loa Loa (eye worm) hypothetical protein 0.0024 0.0009 0.0009
Loa Loa (eye worm) hypothetical protein 0.0021 0.0005 0.0005
Loa Loa (eye worm) hypoxia-induced factor 1 0.0164 0.0158 0.0158
Trichomonas vaginalis phosphofructokinase, putative 0.0111 0.0102 0.0583
Onchocerca volvulus 0.159 0.1676 1
Trichomonas vaginalis AGC family protein kinase 0.0029 0.0014 0.0056
Treponema pallidum nicotinate phosphoribosyltransferase 0.0155 0.0149 0.2228
Echinococcus granulosus carboxylesterase 5A 0.9412 1 1
Mycobacterium tuberculosis Probable soluble pyridine nucleotide transhydrogenase SthA (STH) (NAD(P)(+) transhydrogenase [B-specific]) (nicotinamide nucleot 0.003 0.0015 0.0081
Echinococcus multilocularis FTZ F1 alpha 0.003 0.0015 0.0015
Echinococcus granulosus nicotinic acetylcholine receptor beta 1 subunit 0.0045 0.0031 0.0031
Entamoeba histolytica Niemann-Pick C1 protein, putative 0.0101 0.0091 0.1336
Plasmodium falciparum isocitrate dehydrogenase [NADP], mitochondrial 0.0017 0.0002 0.0044
Loa Loa (eye worm) hypothetical protein 0.0043 0.003 0.0029
Entamoeba histolytica fructose-1,6-bisphosphate aldolase, putative 0.0627 0.065 1
Brugia malayi jmjC domain containing protein 0.0062 0.005 0.0049
Wolbachia endosymbiont of Brugia malayi 4'-phosphopantetheinyl transferase 0.0025 0.001 0.4824
Toxoplasma gondii isocitrate dehydrogenase 0.0017 0.0002 0.0149
Onchocerca volvulus 0.003 0.0015 0.0057
Entamoeba histolytica protein kinase, putative 0.0029 0.0014 0.0145
Brugia malayi hypothetical protein 0.0021 0.0005 0.0005
Onchocerca volvulus 0.0188 0.0184 0.1067
Loa Loa (eye worm) cytoplasmic intermediate filament protein 0.0016 0 0.0000080251
Loa Loa (eye worm) hypothetical protein 0.0029 0.0014 0.0014
Trichomonas vaginalis conserved hypothetical protein 0.0026 0.0011 0.0037
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.003 0.0015 0.0015
Schistosoma mansoni nAChR subunit 0.0045 0.0031 0.0031
Loa Loa (eye worm) intermediate filament tail domain-containing protein 0.0029 0.0015 0.0015
Brugia malayi Iron-sulfur cluster assembly accessory protein 0.0049 0.0036 0.0036
Echinococcus granulosus lamin dm0 0.0029 0.0015 0.0015
Brugia malayi Cytochrome P450 family protein 0.003 0.0015 0.0015
Plasmodium vivax holo-[acyl-carrier-protein] synthase, putative 0.0025 0.001 0.1277
Loa Loa (eye worm) hypothetical protein 0.0026 0.0011 0.0011
Brugia malayi Cation transporter family protein 0.0045 0.0031 0.0031
Echinococcus granulosus nicotinamide phosphoribosyltransferase 0.0836 0.0873 0.0873
Brugia malayi Hypothetical glycine receptor like protein T20B12.9 in chromosome III 0.0045 0.0031 0.0031
Echinococcus granulosus lipoxygenase domain containing protein 0.0024 0.0009 0.0009
Brugia malayi Probable G protein-coupled receptor kinase F19C6.1, putative 0.0027 0.0012 0.0012
Schistosoma mansoni jumonji domain containing protein 0.0017 0.0001 0.0001
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.003 0.0015 0.0962
Mycobacterium tuberculosis Probable 6-phosphofructokinase PfkA (phosphohexokinase) (phosphofructokinase) 0.0111 0.0102 0.0599
Brugia malayi Carboxylesterase family protein 0.159 0.1676 0.1676
Mycobacterium tuberculosis Probable oxidoreductase 0.0219 0.0216 0.1281
Loa Loa (eye worm) hypothetical protein 0.003 0.0015 0.0015
Loa Loa (eye worm) hypothetical protein 0.0045 0.0031 0.0031
Trichomonas vaginalis serine threonine-protein kinase, putative 0.0157 0.015 0.087
Trichomonas vaginalis serine/threonine-protein kinase sgk, putative 0.0027 0.0012 0.0046
Brugia malayi Neurotransmitter-gated ion-channel ligand binding domain containing protein 0.0045 0.0031 0.0031
Schistosoma mansoni axis inhibition protein axin 0.0026 0.0011 0.0011
Echinococcus multilocularis nicotinamide phosphoribosyltransferase 0.0836 0.0873 0.0873
Echinococcus multilocularis Niemann Pick C1 protein 0.0101 0.0091 0.0091
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.003 0.0015 0.0962
Brugia malayi Protein kinase domain containing protein 0.0029 0.0014 0.0014
Loa Loa (eye worm) ligand-Gated ion Channel family member 0.0045 0.0031 0.0031
Loa Loa (eye worm) hypothetical protein 0.003 0.0015 0.0015
Echinococcus granulosus Niemann Pick C1 protein 0.0144 0.0137 0.0137
Schistosoma mansoni jumonji/arid domain-containing protein 0.0062 0.005 0.0049
Loa Loa (eye worm) AGC/GRK/GRK protein kinase 0.0027 0.0012 0.0012
Trichomonas vaginalis phosphofructokinase, putative 0.0111 0.0102 0.0583
Schistosoma mansoni 6-phosphofructokinase 0.0111 0.0102 0.0102
Mycobacterium tuberculosis Probable exodeoxyribonuclease III protein XthA (exonuclease III) (EXO III) (AP endonuclease VI) 0.002 0.0005 0.0017
Schistosoma mansoni acetylcholine receptor subunit beta 0.0021 0.0005 0.0005
Toxoplasma gondii exonuclease III APE 0.002 0.0005 0.0387
Echinococcus granulosus protein kinase c iota type 0.0029 0.0014 0.0014
Schistosoma mansoni BC026374 protein (S09 family) 0.159 0.1676 0.1676
Loa Loa (eye worm) hypothetical protein 0.0021 0.0005 0.0005
Echinococcus multilocularis nicotinic acetylcholine receptor alpha subunit 0.0045 0.0031 0.0031
Entamoeba histolytica hypothetical protein 0.0025 0.001 0.008
Schistosoma mansoni regulator of G protein signaling 17 19 20 (rgs17 19 20) 0.0026 0.0011 0.0011
Trypanosoma brucei rac serine-threonine kinase, putative 0.0029 0.0014 0.0872
Mycobacterium tuberculosis Nicotinic acid phosphoribosyltransferase PncB1 0.0155 0.0149 0.0876
Entamoeba histolytica protein kinase, putative 0.0029 0.0014 0.0145
Echinococcus multilocularis ribosomal protein s6 kinase beta 1 0.0029 0.0014 0.0014
Plasmodium falciparum LCCL domain-containing protein 0.0024 0.0009 0.0523
Loa Loa (eye worm) hypothetical protein 0.0019 0.0003 0.0003
Schistosoma mansoni hypothetical protein 0.0056 0.0043 0.0043
Treponema pallidum diphosphate--fructose-6-phosphate 1-phosphotransferase 0.003 0.0016 0.0169
Echinococcus granulosus thioredoxin glutathione reductase 0.0087 0.0076 0.0076
Onchocerca volvulus 0.159 0.1676 1
Echinococcus granulosus lamin 0.0029 0.0015 0.0015
Echinococcus multilocularis neutral alpha glucosidase AB 0.0037 0.0022 0.0022
Mycobacterium leprae PROBABLE NADH DEHYDROGENASE NDH 0.0197 0.0193 0.6115
Brugia malayi Neurotransmitter-gated ion-channel ligand binding domain containing protein 0.0021 0.0005 0.0005
Onchocerca volvulus 0.0188 0.0184 0.1067
Echinococcus granulosus phd:f box containing protein 0.0017 0.0001 0.0001
Echinococcus multilocularis thioredoxin glutathione reductase 0.0087 0.0076 0.0076
Loa Loa (eye worm) RecQ helicase 0.0023 0.0008 0.0008
Brugia malayi alpha keto acid dehydrogenase complex, E3 component, lipoamide dehydrogenase 0.0022 0.0007 0.0007
Echinococcus multilocularis glycine receptor subunit alpha 1 0.0045 0.0031 0.0031
Brugia malayi glutathione reductase 0.0086 0.0075 0.0075
Schistosoma mansoni phosphatidylserine receptor 0.0017 0.0001 0.0001
Echinococcus granulosus vesicular acetylcholine transporter 0.0219 0.0217 0.0216
Leishmania major hypothetical protein, conserved 0.0027 0.0012 0.0694
Mycobacterium ulcerans 4'-phosphopantetheinyl transferase 0.0025 0.001 0.0031
Schistosoma mansoni nAChR subunit 0.0045 0.0031 0.0031
Loa Loa (eye worm) hypothetical protein 0.0045 0.0031 0.0031
Echinococcus multilocularis jumonji domain containing 1A 0.0017 0.0001 0.0001
Loa Loa (eye worm) hypothetical protein 0.0017 0.0001 0.0001
Echinococcus granulosus Cys loop ligand gated ion channel subunit 0.0021 0.0005 0.0005
Echinococcus multilocularis musashi 0.0029 0.0015 0.0015
Onchocerca volvulus 0.0045 0.0031 0.0153
Brugia malayi jmjC domain containing protein 0.0017 0.0001 0.0001
Trypanosoma brucei trypanothione reductase 0.0086 0.0075 0.5033
Trichomonas vaginalis cat eye syndrome critical region protein 2, cscr2, putative 0.0043 0.0029 0.0145
Brugia malayi acetylcholine receptor protein, alpha-like chain, putative 0.0045 0.0031 0.0031
Echinococcus granulosus Jumonji AT rich interactive domain 1B 0.0017 0.0001 0.0001
Brugia malayi PXA domain containing protein 0.0026 0.0011 0.0011
Brugia malayi hypothetical protein 0.0178 0.0172 0.0172
Mycobacterium ulcerans dihydrolipoamide dehydrogenase 0.003 0.0015 0.0064
Echinococcus granulosus lysosomal alpha glucosidase 0.0165 0.0159 0.0159
Trichomonas vaginalis AGC family protein kinase 0.0029 0.0014 0.0056

Activities

Activity type Activity value Assay description Source Reference
Ki (binding) = 4 uM Inhibitory activity of the compound against Soyabean type 1 Lipoxygenase (SBLO) was determined ChEMBL. No reference
Ki (binding) = 4 uM Inhibitory activity of the compound against Soyabean type 1 Lipoxygenase (SBLO) was determined ChEMBL. No reference

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
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External resources for this compound

No external resources registered for this compound

Bibliographic References

No literature references available for this target.

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