Detailed information for compound 39975

Basic information

Technical information
  • Name: Unnamed compound
  • MW: 468.433 | Formula: C24H30BrN5
  • H donors: 2 H acceptors: 2 LogP: 6.53 Rotable bonds: 7
    Rule of 5 violations (Lipinski): 1
  • SMILES: CCN(C1CCC(CC1)Nc1nc(Nc2cccc(c2)Br)c2c(n1)cccc2)CC
  • InChi: 1S/C24H30BrN5/c1-3-30(4-2)20-14-12-18(13-15-20)27-24-28-22-11-6-5-10-21(22)23(29-24)26-19-9-7-8-17(25)16-19/h5-11,16,18,20H,3-4,12-15H2,1-2H3,(H2,26,27,28,29)
  • InChiKey: HVNJYMZVQKDSNG-UHFFFAOYSA-N  


Substructure search Similarity search

Network

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Synonyms

No synonyms found for this compound

Targets

Known targets for this compound

No curated genes were found associated with this compound

Predicted pathogen targets for this compound

By orthology
No druggable targets predicted by orthology data
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Echinococcus multilocularis programmed cell death protein 6 0.0032 0.0042 0.0041
Onchocerca volvulus Matrix metalloproteinase homolog 0.0048 0.0095 0.0167
Trypanosoma brucei dihydrolipoamide dehydrogenase, point mutation 0.0034 0.0051 0.011
Plasmodium vivax serine-repeat antigen 4 (SERA) 0.0285 0.0833 0.2256
Schistosoma mansoni TGF-beta signal transducer Smad2 0.0024 0.002 0.002
Trypanosoma cruzi calpain-like cysteine peptidase, putative 0.0322 0.0949 0.0948
Treponema pallidum NADH oxidase 0.0034 0.0051 1
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0063 0.0141 0.014
Plasmodium falciparum cysteine proteinase falcipain 2a 0.1143 0.3508 1
Trichomonas vaginalis DNA-dependent protein kinase catalytic subunit-interacting protein, putative 0.0172 0.0481 0.131
Plasmodium falciparum transcriptional regulatory protein sir2b 0.0081 0.0197 0.0558
Brugia malayi Cytochrome P450 family protein 0.0032 0.0044 0.0043
Entamoeba histolytica papain family cysteine protease domain containing protein 0.0285 0.0833 0.2372
Mycobacterium ulcerans extragenic suppressor protein SuhB 0.0039 0.0067 0.16
Onchocerca volvulus 0.0031 0.004 0.0061
Brugia malayi cathepsin Z-like cysteine proteinase 0.0285 0.0833 0.0832
Trypanosoma brucei centrin, putative 0.0172 0.0481 0.1053
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.1143 0.3508 0.9564
Trichomonas vaginalis conserved hypothetical protein 0.0028 0.0032 0.0083
Echinococcus multilocularis caspase 2 0.0058 0.0125 0.0124
Entamoeba histolytica myo-inositol monophosphatase, putative 0.0039 0.0067 0.0187
Trypanosoma cruzi calpain-like cysteine peptidase, putative 0.1201 0.3688 0.3687
Brugia malayi hypothetical protein 0.0047 0.0089 0.0088
Onchocerca volvulus 0.0047 0.0089 0.0157
Brugia malayi intermediate filament protein 0.0055 0.0116 0.0115
Leishmania major hypothetical protein, conserved 0.0221 0.0632 0.1383
Mycobacterium ulcerans beta-lactamase 0.0039 0.0064 0.1536
Trypanosoma cruzi calpain-like cysteine peptidase, putative 0.08 0.2438 0.2437
Leishmania major cysteine peptidase C (CPC),CPC cysteine peptidase, Clan CA, family C1, Cathepsin B-like 0.1195 0.3668 0.8045
Trichomonas vaginalis centrin, putative 0.0028 0.0032 0.0083
Onchocerca volvulus Myosin regulatory light chain 2 homolog 0.0028 0.0032 0.0044
Onchocerca volvulus 0.0285 0.0833 0.162
Echinococcus multilocularis gcn5proteinral control of amino acid synthesis 0.0147 0.0403 0.0402
Trypanosoma brucei calpain-like cysteine peptidase, putative 0.074 0.2251 0.4935
Plasmodium vivax dipeptidyl aminopeptidase 1, putative 0.0285 0.0833 0.2256
Loa Loa (eye worm) cysteine proteinase cathepsin Z 0.0285 0.0833 0.0833
Plasmodium falciparum cysteine proteinase falcipain 3 0.1143 0.3508 1
Trichomonas vaginalis set domain proteins, putative 0.0487 0.1464 0.3989
Loa Loa (eye worm) cytochrome P450 family protein 0.0032 0.0044 0.0044
Onchocerca volvulus 0.1143 0.3508 0.6885
Loa Loa (eye worm) cysteine protease 0.1143 0.3508 0.3508
Toxoplasma gondii centrin, putative 0.0172 0.0481 0.131
Echinococcus granulosus tissue type plasminogen activator 0.0023 0.0016 0.0015
Onchocerca volvulus 0.0041 0.0071 0.0121
Plasmodium falciparum glutathione reductase 0.0034 0.0051 0.0143
Schistosoma mansoni subfamily C1A unassigned peptidase (C01 family) 0.0285 0.0833 0.0833
Echinococcus granulosus cathepsin b 0.3225 1 1
Mycobacterium ulcerans DNA polymerase IV 0.0021 0.0008 0.0178
Schistosoma mansoni cpg binding protein 0.0092 0.0231 0.0231
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0031 0.0041 0.0109
Echinococcus multilocularis hepatocyte nuclear factor 4 alpha 0.0021 0.0009 0.0008
Toxoplasma gondii cathepsin CPC1 0.0285 0.0833 0.2268
Trypanosoma cruzi DNA polymerase eta, putative 0.0048 0.0093 0.0092
Giardia lamblia Cathepsin B precursor 0.1195 0.3668 1
Entamoeba histolytica cysteine protease, putative 0.0285 0.0833 0.2372
Loa Loa (eye worm) hypothetical protein 0.0795 0.2424 0.2424
Schistosoma mansoni cercarial elastase (S01 family) 0.0047 0.0089 0.0089
Echinococcus multilocularis NAD dependent deacetylase sirtuin 6 0.0081 0.0197 0.0196
Leishmania major cysteine peptidase A (CPA) 0.1143 0.3508 0.7694
Echinococcus granulosus FTZ F1 alpha 0.0021 0.0009 0.0008
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0021 0.0009 0.0008
Loa Loa (eye worm) hypothetical protein 0.0021 0.0009 0.0009
Trichomonas vaginalis conserved hypothetical protein 0.002 0.0005 0.0012
Schistosoma mansoni hypothetical protein 0.0031 0.004 0.004
Trichomonas vaginalis Clan CA, family C1, cathepsin B-like cysteine peptidase 0.0285 0.0833 0.2268
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0795 0.2424 0.6607
Plasmodium vivax unspecified product 0.0633 0.1918 0.5198
Loa Loa (eye worm) hypothetical protein 0.0088 0.0219 0.0219
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.1285 0.3951 0.8666
Loa Loa (eye worm) hypothetical protein 0.0048 0.0093 0.0093
Leishmania major hypothetical protein, conserved 0.0176 0.0492 0.1077
Trypanosoma cruzi kinesin, putative 0.074 0.2253 0.2252
Trichomonas vaginalis D-aminoacylase, putative 0.0039 0.0064 0.0172
Trypanosoma cruzi Silent information regulator 2 related protein 3 0.0081 0.0197 0.0196
Schistosoma mansoni ef hand domain family member A2 0.0172 0.0481 0.0481
Echinococcus multilocularis lamin dm0 0.0055 0.0116 0.0115
Echinococcus multilocularis calpain family protein 1, d 0.2111 0.6527 0.6526
Schistosoma mansoni cercarial elastase (S01 family) 0.0047 0.0089 0.0089
Echinococcus granulosus calpain 7 C02 family 0.1201 0.3688 0.3687
Echinococcus granulosus dna polymerase kappa 0.0021 0.0008 0.0007
Echinococcus multilocularis ecdysone induced protein 78C 0.0021 0.0009 0.0008
Giardia lamblia Programmed cell death protein-like protein 0.0028 0.0032 0.0083
Echinococcus multilocularis cysteine protease 0.1143 0.3508 0.3508
Echinococcus granulosus Peptidase S1 S6 chymotrypsin Hap 0.0047 0.0089 0.0088
Trypanosoma cruzi Silent information regulator 2 related protein 1 0.0363 0.1074 0.1073
Brugia malayi Cytochrome P450 family protein 0.0032 0.0044 0.0043
Trypanosoma brucei calpain-like protein, putative 0.1201 0.3688 0.8088
Plasmodium falciparum thioredoxin reductase 0.0034 0.0051 0.0143
Trypanosoma cruzi cysteine peptidase, Clan CA, family C2, putative 0.1042 0.3194 0.3193
Brugia malayi acetyltransferase, GNAT family protein 0.0147 0.0403 0.0402
Schistosoma mansoni cathepsin F (C01 family) 0.1143 0.3508 0.3508
Echinococcus multilocularis NAD dependent deacetylase sirtuin 1 0.0295 0.0864 0.0863
Schistosoma mansoni SmCL2-like peptidase (C01 family) 0.0633 0.1918 0.1917
Loa Loa (eye worm) calpain 5 0.074 0.2253 0.2253
Loa Loa (eye worm) hypothetical protein 0.0055 0.0116 0.0116
Entamoeba histolytica cysteine protease, putative 0.0633 0.1918 0.5464
Echinococcus granulosus cytoplasmic intermediate filament protein 0.0027 0.0027 0.0026
Loa Loa (eye worm) papain family cysteine protease containing protein 0.0348 0.1029 0.1029
Trypanosoma brucei cytochrome P450, putative 0.0032 0.0044 0.0095
Echinococcus granulosus terminal deoxycytidyl transferase rev1 0.0021 0.0008 0.0007
Entamoeba histolytica grainin, putative 0.0176 0.0492 0.14
Loa Loa (eye worm) exodeoxyribonuclease III family protein 0.0018 0.0001 0.0001
Brugia malayi Cathepsin L-like precursor 0.1143 0.3508 0.3508
Trypanosoma cruzi calpain-like cysteine peptidase, putative 0.0681 0.2067 0.2066
Trypanosoma cruzi Silent information regulator 2 related protein 3 0.0081 0.0197 0.0196
Trypanosoma cruzi calmodulin, putative 0.0172 0.0481 0.048
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.148 0.456 1
Trichomonas vaginalis calcium binding protein, putative 0.0028 0.0032 0.0083
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.0285 0.0833 0.0833
Giardia lamblia Cathepsin L-like protease 0.0285 0.0833 0.2268
Leishmania major NAD dependent deacetylase, putative,transcriptional regulator, Sir2 family protein, nicotinic acid mononucleotide 5,6-dimethylbe 0.0081 0.0197 0.0429
Trypanosoma brucei trypanothione reductase 0.0099 0.0254 0.0555
Brugia malayi Protein kinase domain containing protein 0.0023 0.0016 0.0015
Trypanosoma brucei small myristoylated protein 1-2 0.0381 0.113 0.2477
Echinococcus granulosus cathepsin l1 0.1143 0.3508 0.3508
Trypanosoma cruzi cysteine peptidase, Clan CA, family C2, putative 0.0662 0.2008 0.2007
Leishmania major small myristoylated protein 4, putative 0.06 0.1814 0.3977
Echinococcus granulosus calcyphosin protein 0.0028 0.0032 0.003
Loa Loa (eye worm) acetyltransferase 0.0147 0.0403 0.0403
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.0933 0.2853 0.6257
Loa Loa (eye worm) cytochrome P450 family protein 0.0032 0.0044 0.0044
Plasmodium vivax thioredoxin reductase, putative 0.0099 0.0254 0.0686
Loa Loa (eye worm) hypothetical protein 0.0028 0.0032 0.0032
Schistosoma mansoni peptidylglycine monooxygenase 0.0128 0.0342 0.0342
Trichomonas vaginalis calmodulin, putative 0.0172 0.0481 0.131
Loa Loa (eye worm) hypothetical protein 0.0285 0.0833 0.0833
Loa Loa (eye worm) hypothetical protein 0.2392 0.74 0.74
Schistosoma mansoni smad1 5 8 and 0.0024 0.002 0.002
Echinococcus multilocularis proteasome (prosome, macropain) 0.015 0.0412 0.0411
Mycobacterium leprae conserved hypothetical protein 0.0039 0.0064 0.0534
Toxoplasma gondii troponin c, isotype gamma, putative 0.0172 0.0481 0.131
Entamoeba histolytica cysteine protease, putative 0.0285 0.0833 0.2372
Echinococcus multilocularis calmodulin 0.0172 0.0481 0.048
Brugia malayi EF hand family protein 0.0172 0.0481 0.048
Brugia malayi cytoplasmic intermediate filament protein 0.003 0.0036 0.0035
Mycobacterium tuberculosis NADPH-dependent mycothiol reductase Mtr 0.0099 0.0254 0.3469
Entamoeba histolytica acetyltransferase, GNAT family 0.004 0.0068 0.019
Loa Loa (eye worm) hypothetical protein 0.0128 0.0342 0.0342
Brugia malayi Smad1 0.0024 0.002 0.0019
Trichomonas vaginalis chromatin regulatory protein sir2, putative 0.0081 0.0197 0.0534
Echinococcus multilocularis calpain 0.1201 0.3688 0.3687
Entamoeba histolytica cysteine proteinase, putative 0.0633 0.1918 0.5464
Echinococcus multilocularis calpain 7 (C02 family) 0.1201 0.3688 0.3687
Loa Loa (eye worm) matrixin family protein 0.0048 0.0095 0.0095
Plasmodium falciparum proteasome subunit beta type-1, putative 0.0066 0.0151 0.0426
Brugia malayi Trypsin family protein 0.0047 0.0089 0.0088
Brugia malayi Copper type II ascorbate-dependent monooxygenase, C-terminal domain containing protein 0.0063 0.014 0.0139
Loa Loa (eye worm) hypothetical protein 0.0022 0.0012 0.0012
Leishmania major META domain containing protein 0.0221 0.0632 0.1383
Leishmania major small myristoylated protein-1 0.0381 0.113 0.2477
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.3225 1 1
Brugia malayi glutathione reductase 0.0099 0.0254 0.0253
Trichomonas vaginalis Clan CA, family C1, cathepsin B-like cysteine peptidase 0.0285 0.0833 0.2268
Schistosoma mansoni subfamily S1A unassigned peptidase (S01 family) 0.0047 0.0089 0.0089
Plasmodium falciparum cysteine proteinase falcipain 2b 0.1143 0.3508 1
Leishmania major phospholipase c-like protein 0.0172 0.0481 0.1053
Brugia malayi Papain family cysteine protease containing protein 0.0285 0.0833 0.0832
Loa Loa (eye worm) hypothetical protein 0.0047 0.0089 0.0089
Plasmodium falciparum serine repeat antigen 9 0.0285 0.0833 0.2372
Mycobacterium tuberculosis Probable nitrite reductase [NAD(P)H] large subunit [FAD flavoprotein] NirB 0.0227 0.0651 0.8917
Leishmania major hypothetical protein, conserved 0.0039 0.0064 0.0138
Loa Loa (eye worm) hypothetical protein 0.0047 0.0089 0.0089
Loa Loa (eye worm) myosin regulatory light chain 1 0.0028 0.0032 0.0032
Mycobacterium ulcerans esterase/lipase LipP 0.0039 0.0064 0.1536
Trichomonas vaginalis chromatin regulatory protein sir2, putative 0.0295 0.0864 0.2354
Mycobacterium ulcerans dihydrolipoamide dehydrogenase, LpdB 0.0034 0.0051 0.1225
Schistosoma mansoni Mername-AA248 (C02 family) 0.1201 0.3688 0.3688
Brugia malayi Nuclear hormone receptor family member nhr-14 0.0021 0.0009 0.0008
Schistosoma mansoni cathepsin s 0.0348 0.1029 0.1028
Schistosoma mansoni hypothetical protein 0.0047 0.009 0.009
Loa Loa (eye worm) cytochrome P450 family protein 0.0033 0.0046 0.0046
Schistosoma mansoni proteasome catalytic subunit 3 (T01 family) 0.015 0.0412 0.0411
Plasmodium vivax dihydrolipoyl dehydrogenase, mitochondrial, putative 0.0034 0.0051 0.0136
Trichomonas vaginalis chromobox protein, putative 0.007 0.0163 0.044
Loa Loa (eye worm) hypothetical protein 0.0026 0.0024 0.0024
Onchocerca volvulus 0.0055 0.0116 0.021
Schistosoma mansoni thyroid hormone receptor 0.0156 0.043 0.043
Echinococcus granulosus cathepsin L 0.0285 0.0833 0.0832
Giardia lamblia Cysteine protease 0.0285 0.0833 0.2268
Entamoeba histolytica calcium binding family protein 0.0172 0.0481 0.1369
Brugia malayi Matrixin family protein 0.0022 0.0012 0.0011
Trichomonas vaginalis calmodulin, putative 0.0172 0.0481 0.131
Plasmodium vivax vivapain-2 0.1143 0.3508 0.9513
Trichomonas vaginalis conserved hypothetical protein 0.002 0.0005 0.0012
Plasmodium falciparum centrin-4 0.0028 0.0032 0.0087
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.1143 0.3508 0.9564
Trypanosoma cruzi hypothetical protein, conserved 0.0023 0.0016 0.0015
Schistosoma mansoni calmodulin 0.0172 0.0481 0.0481
Leishmania major cathepsin L-like protease 0.1285 0.3951 0.8666
Trichomonas vaginalis D-aminoacylase, putative 0.0039 0.0064 0.0172
Loa Loa (eye worm) hypothetical protein 0.0047 0.0089 0.0089
Wolbachia endosymbiont of Brugia malayi fructose-1,6-bisphosphatase 0.0039 0.0067 1
Echinococcus multilocularis thioredoxin glutathione reductase 0.0099 0.0254 0.0253
Schistosoma mansoni cercarial elastase (S01 family) 0.0047 0.0089 0.0089
Brugia malayi Copper type II ascorbate-dependent monooxygenase, C-terminal domain containing protein 0.024 0.0693 0.0692
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0024 0.0018 0.0018
Entamoeba histolytica calmodulin, putative 0.0028 0.0032 0.0087
Giardia lamblia Cathepsin B precursor 0.1195 0.3668 1
Entamoeba histolytica cysteine proteinase, putative 0.0795 0.2424 0.6907
Trichomonas vaginalis conserved hypothetical protein 0.0285 0.0833 0.2268
Trypanosoma cruzi PAB1-binding protein , putative 0.0052 0.0107 0.0106
Brugia malayi beta-lactamase family protein 0.0039 0.0064 0.0063
Entamoeba histolytica deoxycytidyl transferase, putative 0.0021 0.0008 0.0021
Trichomonas vaginalis D-aminoacylase, putative 0.0039 0.0064 0.0172
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.0285 0.0833 0.0833
Trypanosoma cruzi major cysteine proteinase, putative 0.0285 0.0833 0.0832
Mycobacterium tuberculosis Putative ferredoxin reductase 0.0227 0.0651 0.8917
Schistosoma mansoni dihydrolipoamide dehydrogenase 0.0034 0.0051 0.0051
Plasmodium vivax unspecified product 0.0348 0.1029 0.2787
Giardia lamblia Cathepsin B precursor 0.0285 0.0833 0.2268
Schistosoma mansoni mitochondrial solute carrier 0.0172 0.0481 0.0481
Echinococcus multilocularis chromatin regulatory protein sir2 0.0363 0.1074 0.1073
Onchocerca volvulus Mitochondrial Rho GTPase homolog 0.0028 0.0032 0.0044
Brugia malayi calpain family protein 1 0.2852 0.8835 0.8835
Loa Loa (eye worm) sirtuin 4 0.0081 0.0197 0.0197
Schistosoma mansoni calmodulin 0.0172 0.0481 0.0481
Schistosoma mansoni FTZ-F1 nuclear receptor-like protein 0.0021 0.0009 0.0009
Entamoeba histolytica NAD-dependent deacetylase 1, putative 0.0081 0.0197 0.0558
Trypanosoma cruzi cytochrome P450, putative 0.0032 0.0044 0.0043
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.1285 0.3951 0.8666
Brugia malayi Nuclear hormone receptor family member nhr-31 0.0021 0.0009 0.0008
Plasmodium vivax calpain, putative 0.1201 0.3688 1
Trypanosoma cruzi calpain-like cysteine peptidase, putative 0.0322 0.0949 0.0948
Loa Loa (eye worm) hypothetical protein 0.0027 0.0027 0.0027
Giardia lamblia Transcriptional regulator, Sir2 family 0.0081 0.0197 0.0534
Brugia malayi transcriptional regulator, Sir2 family protein 0.0081 0.0197 0.0196
Trichomonas vaginalis calmodulin, putative 0.0176 0.0492 0.1339
Echinococcus multilocularis survival motor neuron protein 1 0.0228 0.0656 0.0655
Echinococcus multilocularis centrin 2 0.0172 0.0481 0.048
Entamoeba histolytica calmodulin, putative 0.0172 0.0481 0.1369
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0031 0.0041 0.0109
Schistosoma mansoni cpg binding protein 0.0087 0.0215 0.0215
Brugia malayi cathepsin L precursor 0.0285 0.0833 0.0832
Plasmodium vivax NAD-dependent deacetylase, putative 0.0081 0.0197 0.0531
Plasmodium falciparum serine repeat antigen 1 0.0285 0.0833 0.2372
Loa Loa (eye worm) hypothetical protein 0.0148 0.0407 0.0407
Trypanosoma brucei caltractin, putative 0.02 0.0569 0.1246
Echinococcus granulosus proteasome prosome macropain subunit beta 0.0066 0.0151 0.015
Echinococcus granulosus chromobox protein 1 0.007 0.0163 0.0161
Trichomonas vaginalis conserved hypothetical protein 0.002 0.0005 0.0012
Loa Loa (eye worm) RecQ helicase 0.0023 0.0015 0.0015
Mycobacterium tuberculosis Probable hydrolase 0.0039 0.0064 0.0865
Schistosoma mansoni myosin regulatory light chain 0.0028 0.0032 0.0031
Echinococcus multilocularis Tolloid protein 1 0.0092 0.023 0.0229
Leishmania major dihydrolipoamide dehydrogenase, putative 0.0034 0.0051 0.011
Trichomonas vaginalis calcium binding proteins, putative 0.0172 0.0481 0.131
Echinococcus multilocularis atpase aaa+ type core atpase aaa type core 0.2439 0.7547 0.7546
Trichomonas vaginalis conserved hypothetical protein 0.0022 0.0013 0.0032
Schistosoma mansoni hypothetical protein 0.0041 0.0071 0.0071
Giardia lamblia Cysteine protease 0.0285 0.0833 0.2268
Trichomonas vaginalis conserved hypothetical protein 0.0172 0.0481 0.131
Trypanosoma cruzi hypothetical protein, conserved 0.0357 0.1058 0.1057
Loa Loa (eye worm) hypothetical protein 0.0047 0.009 0.009
Trypanosoma brucei calpain-like cysteine peptidase, putative 0.028 0.0816 0.1787
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.1195 0.3668 0.3668
Brugia malayi photoreceptor-specific nuclear receptor 0.0021 0.0009 0.0008
Trypanosoma brucei unspecified product 0.0021 0.0008 0.0016
Trypanosoma cruzi cysteine peptidase, Clan CA, family C2, putative 0.1201 0.3688 0.3687
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0031 0.0041 0.0109
Onchocerca volvulus 0.0055 0.0116 0.021
Loa Loa (eye worm) hypothetical protein 0.0102 0.026 0.026
Giardia lamblia Dipeptidyl-peptidase I precursor 0.0285 0.0833 0.2268
Trypanosoma brucei cysteine peptidase, Clan CA, family C2, putative 0.0662 0.2008 0.4402
Brugia malayi NAD-dependent deacetylase SIRT1 0.0295 0.0864 0.0863
Schistosoma mansoni cathepsin F (C01 family) 0.1143 0.3508 0.3508
Trypanosoma cruzi DNA polymerase eta, putative 0.0034 0.0049 0.0048
Loa Loa (eye worm) papain family cysteine protease containing protein 0.1143 0.3508 0.3508
Echinococcus multilocularis dnaJ subfamily B 0.0814 0.2483 0.2482
Loa Loa (eye worm) Smad1 0.0024 0.002 0.002
Mycobacterium tuberculosis NAD(P)H quinone reductase LpdA 0.0252 0.073 1
Leishmania major centrin, putative,caltractin, putative 0.0172 0.0481 0.1053
Loa Loa (eye worm) papain family cysteine protease containing protein 0.0285 0.0833 0.0833
Mycobacterium tuberculosis Inositol-1-monophosphatase SuhB 0.0035 0.0054 0.0725
Trichomonas vaginalis Clan CA, family C2, calpain-like cysteine peptidase 0.046 0.1379 0.3758
Loa Loa (eye worm) hypothetical protein 0.0031 0.004 0.004
Loa Loa (eye worm) thioredoxin reductase 0.0099 0.0254 0.0254
Brugia malayi MH1 domain containing protein 0.0024 0.002 0.0019
Toxoplasma gondii calcium binding egf domain-containing protein 0.003 0.0036 0.0096
Echinococcus granulosus caspase 2 0.0058 0.0125 0.0124
Echinococcus multilocularis geminin 0.1028 0.3149 0.3148
Schistosoma mansoni intermediate filament proteins 0.0055 0.0116 0.0116
Echinococcus granulosus calcium uptake protein 1 0.0176 0.0492 0.0491
Trypanosoma brucei cysteine peptidase, Clan CA, family C2, putative 0.1402 0.4316 0.9466
Trichomonas vaginalis caltractin, putative 0.0028 0.0032 0.0083
Loa Loa (eye worm) transcriptional regulator 0.0363 0.1074 0.1074
Brugia malayi cathepsin L-like cysteine proteinase, identical 0.0348 0.1029 0.1028
Toxoplasma gondii calpain family cysteine protease domain-containing protein 0.046 0.1379 0.3758
Brugia malayi Myosin regulatory light chain 1 0.0028 0.0032 0.003
Trichomonas vaginalis chromatin regulatory protein sir2, putative 0.0295 0.0864 0.2354
Leishmania major DNA polymerase kappa, putative 0.0021 0.0008 0.0016
Echinococcus multilocularis sarcoplasmic calcium binding protein 0.0172 0.0481 0.048
Trypanosoma cruzi cysteine peptidase C (CPC), putative 0.1195 0.3668 0.3667
Trichomonas vaginalis calcineurin B subunit, putative 0.0172 0.0481 0.131
Giardia lamblia Histone acetyltransferase GCN5 0.004 0.0068 0.0182
Mycobacterium tuberculosis Proteasome beta subunit PrcB; assembles with alpha subunit PrcA. 0.015 0.0412 0.5632
Entamoeba histolytica EF-hand calcium-binding domain containing protein 0.0172 0.0481 0.1369
Trypanosoma cruzi major cysteine proteinase, putative 0.0427 0.1276 0.1275
Loa Loa (eye worm) hypothetical protein 0.0041 0.0071 0.0071
Echinococcus granulosus survival motor neuron protein 1 0.0228 0.0656 0.0655
Trypanosoma cruzi centrin, putative 0.02 0.0569 0.0568
Trichomonas vaginalis conserved hypothetical protein 0.0357 0.1058 0.2883
Brugia malayi hypothetical protein 0.0052 0.0107 0.0106
Brugia malayi Papain family cysteine protease containing protein 0.0633 0.1918 0.1917
Toxoplasma gondii EF hand domain-containing protein 0.0172 0.0481 0.131
Echinococcus granulosus glycoprotein Antigen 5 0.0047 0.0089 0.0088
Echinococcus multilocularis subfamily S1A unassigned peptidase (S01 family) 0.0047 0.0089 0.0088
Brugia malayi MH1 domain containing protein 0.0024 0.002 0.0019
Trichomonas vaginalis chromatin regulatory protein sir2, putative 0.0363 0.1074 0.2926
Trypanosoma brucei Small kinetoplastid calpain-related protein 1-4 0.0221 0.0632 0.1383
Echinococcus multilocularis calpain A 0.3028 0.9383 0.9383
Schistosoma mansoni calpain (C02 family) 0.1201 0.3688 0.3688
Leishmania major dihydrolipoamide dehydrogenase, putative 0.0034 0.0051 0.011
Leishmania major calmodulin, putative 0.0172 0.0481 0.1053
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.0662 0.2008 0.4402
Loa Loa (eye worm) matrixin family protein 0.0053 0.0108 0.0108
Leishmania major DNA polymerase eta, putative 0.0048 0.0093 0.0203
Trypanosoma brucei I/6 autoantigen 0.0172 0.0481 0.1053
Onchocerca volvulus 0.0047 0.0089 0.0157
Echinococcus multilocularis family C2 unassigned peptidase (C02 family) 0.3024 0.9373 0.9373
Brugia malayi Trypsin-like protease protein 5 0.0047 0.0089 0.0088
Schistosoma mansoni subfamily S1A unassigned peptidase (S01 family) 0.0054 0.0114 0.0113
Trichomonas vaginalis calmodulin, putative 0.02 0.0569 0.1548
Trichomonas vaginalis DNA helicase recq, putative 0.0023 0.0015 0.0038
Mycobacterium tuberculosis Probable NADH dehydrogenase Ndh 0.0227 0.0651 0.8917
Trypanosoma cruzi calpain-like cysteine peptidase, putative 0.0322 0.0949 0.0948
Trypanosoma brucei DNA polymerase kappa, putative 0.0021 0.0008 0.0016
Trichomonas vaginalis conserved hypothetical protein 0.002 0.0005 0.0012
Schistosoma mansoni SmCB2 peptidase (C01 family) 0.3225 1 1
Leishmania major DNA polymerase eta, putative 0.0034 0.0049 0.0105
Brugia malayi Nuclear hormone receptor family member nhr-1 0.0021 0.0009 0.0008
Echinococcus multilocularis calmodulin 0.0172 0.0481 0.048
Loa Loa (eye worm) hypothetical protein 0.0047 0.0089 0.0089
Schistosoma mansoni myosin light chain 0.0028 0.0032 0.0031
Plasmodium falciparum histone acetyltransferase GCN5 0.004 0.0068 0.019
Brugia malayi Cytochrome P450 family protein 0.0033 0.0046 0.0045
Onchocerca volvulus Cell death protein 3 homolog 0.0058 0.0125 0.0228
Giardia lamblia Calmodulin 0.0028 0.0032 0.0083
Echinococcus multilocularis peptidyl glycine alpha amidating monooxygenase 0.024 0.0693 0.0692
Mycobacterium tuberculosis Conserved protein 0.0039 0.0064 0.0865
Loa Loa (eye worm) hypothetical protein 0.0047 0.0089 0.0089
Echinococcus granulosus calmodulin 0.0172 0.0481 0.048
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.1285 0.3951 0.8666
Loa Loa (eye worm) pigment dispersing factor receptor c 0.0148 0.0407 0.0407
Giardia lamblia Hypothetical protein 0.0285 0.0833 0.2268
Loa Loa (eye worm) hypothetical protein 0.0021 0.0009 0.0009
Trichomonas vaginalis conserved hypothetical protein 0.002 0.0005 0.0012
Trichomonas vaginalis chromatin regulatory protein sir2, putative 0.0295 0.0864 0.2354
Echinococcus granulosus EF HAND 1 calcium binding site 0.0172 0.0481 0.048
Echinococcus granulosus neuronal calcium sensor 0.0172 0.0481 0.048
Loa Loa (eye worm) hypothetical protein 0.0285 0.0833 0.0833
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.1143 0.3508 0.9564
Trypanosoma cruzi calpain-like cysteine peptidase, putative 0.1042 0.3194 0.3193
Schistosoma mansoni chromobox protein 0.007 0.0163 0.0162
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.0285 0.0833 0.0833
Loa Loa (eye worm) histone methyltransferase 0.0029 0.0035 0.0035
Giardia lamblia NADH oxidase lateral transfer candidate 0.0034 0.0051 0.0137
Echinococcus granulosus centrin 2 0.0172 0.0481 0.048
Loa Loa (eye worm) hypothetical protein 0.0285 0.0833 0.0833
Plasmodium vivax serine-repeat antigen 4 (SERA), putative 0.0285 0.0833 0.2256
Toxoplasma gondii LsmAD domain-containing protein 0.0052 0.0107 0.0289
Toxoplasma gondii pyruvate dehydrogenase complex subunit PDH-E3II 0.0034 0.0051 0.0137
Echinococcus multilocularis bloom syndrome protein 0.0023 0.0015 0.0014
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.1285 0.3951 0.8666
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.1143 0.3508 0.9564
Trypanosoma cruzi cysteine proteinase, putative 0.0633 0.1918 0.1917
Onchocerca volvulus Matrilysin homolog 0.0048 0.0095 0.0167
Toxoplasma gondii EF hand domain-containing protein 0.0028 0.0032 0.0083
Schistosoma mansoni cercarial elastase (S01 family) 0.0047 0.0089 0.0089
Entamoeba histolytica proteasome subunit beta type 1, putative 0.0066 0.0151 0.0426
Trypanosoma cruzi cysteine peptidase, putative 0.1285 0.3951 0.3951
Trypanosoma brucei Domain of unknown function (DUF1935), putative 0.0221 0.0632 0.1383
Trypanosoma brucei cysteine peptidase, Clan CA, family C2, putative 0.028 0.0816 0.1787
Toxoplasma gondii ImpB/MucB/SamB family protein 0.0034 0.0049 0.0131
Trypanosoma brucei META domain/Domain of unknown function (DUF1935), putative 0.0221 0.0632 0.1383
Echinococcus multilocularis Ataxin 2, N terminal,domain containing protein 0.0023 0.0017 0.0016
Plasmodium falciparum serine repeat antigen 4 0.0285 0.0833 0.2372
Schistosoma mansoni subfamily S1A unassigned peptidase (S01 family) 0.0054 0.0114 0.0113
Brugia malayi Trypsin family protein 0.0047 0.0089 0.0088
Trypanosoma cruzi hypothetical protein, conserved 0.0039 0.0064 0.0063
Brugia malayi Matrixin family protein 0.0022 0.0012 0.0011
Trichomonas vaginalis DNA polymerase IV / kappa, putative 0.0021 0.0008 0.002
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0137 0.0372 0.0371
Trypanosoma brucei Component of motile flagella 41 0.0172 0.0481 0.1053
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.0996 0.305 0.6688
Trypanosoma cruzi calpain-like cysteine peptidase, putative 0.0681 0.2067 0.2066
Echinococcus granulosus NAD dependent deacetylase sirtuin 7 0.0081 0.0197 0.0196
Leishmania major small myristoylated protein-3, putative 0.0322 0.0949 0.208
Schistosoma mansoni hypothetical protein 0.0055 0.0117 0.0116
Entamoeba histolytica Sir2 family transcriptional regulator, putative 0.0363 0.1074 0.306
Trichomonas vaginalis calcineurin B subunit, putative 0.0176 0.0492 0.1339
Loa Loa (eye worm) hypothetical protein 0.0021 0.0009 0.0009
Onchocerca volvulus Heterochromatin protein 1 homolog 0.0042 0.0076 0.0131
Schistosoma mansoni subfamily S1A unassigned peptidase (S01 family) 0.0047 0.0089 0.0089
Entamoeba histolytica cysteine protease, putative 0.0633 0.1918 0.5464
Loa Loa (eye worm) hypothetical protein 0.024 0.0693 0.0693
Onchocerca volvulus Cathepsin L homolog 0.1143 0.3508 0.6885
Brugia malayi Nuclear hormone receptor family member nhr-40 0.0021 0.0009 0.0008
Brugia malayi Intermediate filament tail domain containing protein 0.0055 0.0116 0.0115
Loa Loa (eye worm) matrix metalloproteinase 0.0022 0.0012 0.0012
Loa Loa (eye worm) nuclear Hormone Receptor family member 0.0021 0.0009 0.0009
Trichomonas vaginalis Clan CA, family C1, cathepsin H-like cysteine peptidase 0.0285 0.0833 0.2268
Brugia malayi fibroinase precursor 0.0285 0.0833 0.0832
Echinococcus granulosus FTZ F1 nuclear receptor protein 0.0021 0.0009 0.0008
Schistosoma mansoni myosin regulatory light chain 0.0028 0.0032 0.0031
Loa Loa (eye worm) hypothetical protein 0.0172 0.0481 0.0481
Plasmodium falciparum cysteine repeat modular protein 1 0.0023 0.0016 0.0042
Trichomonas vaginalis conserved hypothetical protein 0.002 0.0005 0.0012
Brugia malayi hypothetical protein 0.013 0.035 0.0349
Trichomonas vaginalis cat eye syndrome critical region protein 2, cscr2, putative 0.0043 0.0079 0.0212
Trypanosoma cruzi cysteine peptidase, clan CA, family C1, cathepsin L-like, putative 0.0938 0.2867 0.2866
Echinococcus granulosus histone acetyltransferase KAT2B 0.0043 0.0079 0.0078
Onchocerca volvulus 0.0023 0.0016 0.0013
Brugia malayi nuclear hormone receptor 0.0021 0.0009 0.0008
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0137 0.0372 0.0371
Trypanosoma brucei DNA polymerase IV, putative 0.0021 0.0008 0.0016
Echinococcus multilocularis cadherin EGF LAG seven pass G type receptor 0.0047 0.009 0.0089
Entamoeba histolytica calcium-binding protein, putative 0.0172 0.0481 0.1369
Trypanosoma cruzi calpain-like cysteine peptidase, putative 0.0582 0.1758 0.1757
Trichomonas vaginalis DNA polymerase eta, putative 0.0021 0.0008 0.002
Onchocerca volvulus Cathepsin L homolog 0.0285 0.0833 0.162
Loa Loa (eye worm) hypothetical protein 0.0021 0.0009 0.0009
Mycobacterium tuberculosis Probable reductase 0.0227 0.0651 0.8917
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0031 0.0041 0.0109
Trypanosoma brucei cysteine peptidase, Clan CA, family C2, putative 0.1042 0.3194 0.7003
Entamoeba histolytica cysteine protease, putative 0.0285 0.0833 0.2372
Brugia malayi Matrix metalloprotease, N-terminal domain containing protein 0.0027 0.0027 0.0026
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0034 0.0051 0.005
Loa Loa (eye worm) bone morphogenetic protein 1b 0.0092 0.023 0.023
Mycobacterium tuberculosis Probable esterase LipL 0.0039 0.0064 0.0865
Brugia malayi Papain family cysteine protease containing protein 0.0633 0.1918 0.1917
Trypanosoma brucei DNA polymerase kappa, putative 0.0021 0.0008 0.0016
Echinococcus granulosus subfamily S1A unassigned peptidase S01 family 0.0047 0.0089 0.0088
Loa Loa (eye worm) hypothetical protein 0.0027 0.0027 0.0027
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0021 0.0009 0.0008
Trichomonas vaginalis penicillin-binding protein, putative 0.0039 0.0064 0.0172
Echinococcus multilocularis Smad4 0.0024 0.002 0.0019
Trypanosoma brucei kinesin, putative 0.074 0.2253 0.4939
Trichomonas vaginalis Family T1, proteasome beta subunit, threonine peptidase 0.015 0.0412 0.112
Echinococcus multilocularis histone lysine N methyltransferase SETMAR 0.0063 0.0141 0.014
Schistosoma mansoni hypothetical protein 0.0814 0.2483 0.2483
Toxoplasma gondii cathepsin CPC2 0.0285 0.0833 0.2268
Echinococcus multilocularis beta LACTamase domain containing family member 0.0039 0.0064 0.0063
Giardia lamblia Dipeptidyl-peptidase I precursor 0.0285 0.0833 0.2268
Giardia lamblia Cathepsin L precursor 0.0285 0.0833 0.2268
Echinococcus multilocularis calumenin 0.0176 0.0492 0.0491
Echinococcus multilocularis tissue type plasminogen activator 0.0023 0.0016 0.0015
Trichomonas vaginalis conserved hypothetical protein 0.002 0.0005 0.0012
Leishmania major hypothetical protein, conserved 0.0221 0.0632 0.1383
Trichomonas vaginalis Clan CA, family C1, cathepsin F-like cysteine peptidase 0.0285 0.0833 0.2268
Echinococcus multilocularis apoptotic protease activating factor 1 0.0041 0.0071 0.007
Trypanosoma cruzi I/6 autoantigen, putative 0.0172 0.0481 0.048
Mycobacterium ulcerans hypothetical protein 0.0047 0.0089 0.2146
Trichomonas vaginalis conserved hypothetical protein 0.0172 0.0481 0.131
Trypanosoma brucei cysteine peptidase, Clan CA, family C2, putative 0.0322 0.0949 0.208
Loa Loa (eye worm) hypothetical protein 0.0214 0.0611 0.0611
Schistosoma mansoni dopamine-beta-monooxygenase 0.0128 0.0342 0.0342
Trypanosoma cruzi cysteine peptidase, putative 0.0633 0.1918 0.1917
Echinococcus granulosus matrix metallopeptidase 7 M10 family 0.0079 0.0191 0.019
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.1143 0.3508 0.9564
Giardia lamblia Cathepsin B precursor 0.0285 0.0833 0.2268
Mycobacterium ulcerans cytochrome P450 185A4 Cyp185A4 0.0032 0.0044 0.1049
Brugia malayi Cathepsin L-like precursor 0.1143 0.3508 0.3508
Brugia malayi cathepsin L-like precursor 0.0795 0.2424 0.2423
Entamoeba histolytica hypothetical protein, conserved 0.0081 0.0197 0.0558
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.1143 0.3508 0.9564
Loa Loa (eye worm) hypothetical protein 0.0021 0.0009 0.0009
Brugia malayi Copper type II ascorbate-dependent monooxygenase, N-terminal domain containing protein 0.0065 0.0146 0.0145
Trichomonas vaginalis glutathione reductase, putative 0.0034 0.0051 0.0137
Trichomonas vaginalis Clan CA, family C2, calpain-like cysteine peptidase 0.046 0.1379 0.3758
Onchocerca volvulus 0.1651 0.5092 1
Onchocerca volvulus 0.0039 0.0064 0.0108
Leishmania major centrin, putative 0.0172 0.0481 0.1053
Trichomonas vaginalis kakapo, putative 0.0028 0.0032 0.0083
Trypanosoma cruzi PAB1-binding protein , putative 0.0052 0.0107 0.0106
Echinococcus multilocularis lamin 0.0055 0.0116 0.0115
Echinococcus granulosus intermediate filament protein 0.0055 0.0116 0.0115
Schistosoma mansoni subfamily M12A unassigned peptidase (M12 family) 0.0092 0.023 0.023
Brugia malayi beta-lactamase family protein 0.0039 0.0064 0.0063
Loa Loa (eye worm) Papain cysteine protease/cathepsin propeptide inhibitor-containing protein 0.1143 0.3508 0.3508
Brugia malayi Probable myosin regulatory light chain 0.0032 0.0042 0.0041
Loa Loa (eye worm) beta-LACTamase domain containing family member 0.0039 0.0064 0.0064
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0633 0.1918 0.5226
Brugia malayi Low-density lipoprotein receptor repeat class B containing protein 0.0027 0.0027 0.0026
Echinococcus multilocularis Mitotic checkpoint protein PRCC, C terminal 0.0135 0.0364 0.0363
Loa Loa (eye worm) hypothetical protein 0.046 0.1379 0.1379
Loa Loa (eye worm) hypothetical protein 0.0026 0.0024 0.0024
Toxoplasma gondii cathepsin CPL 0.1143 0.3508 0.9564
Trichomonas vaginalis Clan CA, family C1, cathepsin B-like cysteine peptidase 0.1195 0.3668 1
Entamoeba histolytica cysteine proteinase, putative 0.1143 0.3508 1
Echinococcus multilocularis smad 0.0024 0.002 0.0019
Leishmania major hypothetical protein, unknown function 0.046 0.1379 0.3023
Mycobacterium leprae Probable lipase LipE 0.0039 0.0064 0.0534
Trichomonas vaginalis chromatin regulatory protein sir2, putative 0.0363 0.1074 0.2926
Trypanosoma cruzi Silent information regulator 2 related protein 1 0.0363 0.1074 0.1073
Echinococcus multilocularis hypothetical protein 0.1201 0.3688 0.3687
Trypanosoma cruzi calpain cysteine peptidase, putative 0.148 0.456 0.4559
Loa Loa (eye worm) beta-lactamase 0.0039 0.0064 0.0064
Leishmania major proteasome beta 5 subunit, putative 0.015 0.0412 0.0901
Trypanosoma cruzi dihydrolipoyl dehydrogenase, putative 0.0034 0.0051 0.005
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0021 0.0009 0.0008
Brugia malayi Iron-sulfur cluster assembly accessory protein 0.0047 0.0089 0.0088
Trichomonas vaginalis Crustacean calcium-binding protein, putative 0.0172 0.0481 0.131
Brugia malayi RasGEF domain containing protein 0.0028 0.0032 0.003
Schistosoma mansoni cercarial elastase (S01 family) 0.0047 0.0089 0.0089
Schistosoma mansoni hypothetical protein 0.1028 0.3149 0.3148
Onchocerca volvulus 0.1143 0.3508 0.6885
Trypanosoma brucei Calpain-like protein 1.2 0.0834 0.2545 0.5581
Plasmodium vivax histone acetyltransferase GCN5, putative 0.0043 0.0079 0.0211
Echinococcus granulosus nuclear factor of activated T cells 5 0.0079 0.019 0.0189
Trypanosoma cruzi DNA polymerase kappa, putative 0.0021 0.0008 0.0007
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.1285 0.3951 0.8666
Echinococcus multilocularis chromobox protein 1 0.007 0.0163 0.0161
Entamoeba histolytica cysteine protease, putative 0.0633 0.1918 0.5464
Onchocerca volvulus 0.0047 0.0089 0.0157
Trichomonas vaginalis centrin, putative 0.0028 0.0032 0.0083
Echinococcus granulosus laminin 0.003 0.0036 0.0035
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0063 0.0141 0.014
Loa Loa (eye worm) intermediate filament tail domain-containing protein 0.0055 0.0116 0.0116
Leishmania major small myristoylated protein-2 0.0693 0.2106 0.4617
Schistosoma mansoni chromatin regulatory protein sir2 0.0081 0.0197 0.0197
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.1285 0.3951 0.8666
Trypanosoma brucei calpain-like protein, putative 0.1201 0.3688 0.8088
Schistosoma mansoni cercarial elastase (S01 family) 0.0047 0.0089 0.0089
Echinococcus granulosus Ataxin 2 N terminaldomain containing protein 0.0023 0.0017 0.0016
Loa Loa (eye worm) hypothetical protein 0.0039 0.0064 0.0064
Entamoeba histolytica calpain family cysteine protease, putative 0.046 0.1379 0.3929
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.0996 0.305 0.6688
Plasmodium vivax serine-repeat antigen (SERA), putative 0.0285 0.0833 0.2256
Trichomonas vaginalis Clan CA, family C2, calpain-like cysteine peptidase 0.046 0.1379 0.3758
Giardia lamblia Cysteine protease 0.0285 0.0833 0.2268
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0021 0.0009 0.0008
Echinococcus multilocularis cathepsin l cysteine peptidase 0.1143 0.3508 0.3508
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0031 0.0041 0.0109
Schistosoma mansoni centrin 0.0172 0.0481 0.0481
Loa Loa (eye worm) hypothetical protein 0.0022 0.0012 0.0012
Loa Loa (eye worm) hypothetical protein 0.3225 1 1
Schistosoma mansoni family A2 unassigned peptidase (A02 family) 0.0225 0.0647 0.0647
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0021 0.0009 0.0008
Echinococcus granulosus histone lysine methyltransferase setb 0.0063 0.0141 0.014
Trypanosoma cruzi myo-inositol-1(or 4)-monophosphatase 1, putative 0.0039 0.0067 0.0066
Brugia malayi Pre-SET motif family protein 0.0063 0.0141 0.014
Echinococcus granulosus TGF beta signal transducer SmadC 0.0024 0.002 0.0019
Trichomonas vaginalis chromobox protein, putative 0.0042 0.0076 0.0204
Schistosoma mansoni subfamily C1A unassigned peptidase (C01 family) 0.0285 0.0833 0.0833
Schistosoma mansoni hypothetical protein 0.0047 0.009 0.009
Leishmania major cathepsin L-like protease 0.1143 0.3508 0.7694
Trichomonas vaginalis penicillin-binding protein, putative 0.0039 0.0064 0.0172
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.1143 0.3508 0.9564
Brugia malayi steroid hormone receptor 0.0021 0.0009 0.0008
Brugia malayi Chymotrypsin-like protease CTRL-1 precursor 0.0047 0.0089 0.0088
Schistosoma mansoni subfamily S1A unassigned peptidase (S01 family) 0.0047 0.0089 0.0089
Trypanosoma brucei DNA polymerase eta, putative 0.0048 0.0093 0.0203
Loa Loa (eye worm) hypothetical protein 0.0039 0.0064 0.0064
Mycobacterium tuberculosis Probable oxidoreductase 0.0252 0.073 1
Mycobacterium tuberculosis Probable conserved lipoprotein 0.0039 0.0064 0.0865
Toxoplasma gondii histone lysine acetyltransferase GCN5-B 0.0043 0.0079 0.0212
Trypanosoma cruzi Present in the outer mitochondrial membrane proteome 33 0.0176 0.0492 0.0491
Plasmodium vivax hypothetical protein, conserved 0.0081 0.0197 0.0531
Schistosoma mansoni lamin 0.0055 0.0116 0.0116
Echinococcus multilocularis nuclear factor of activated T cells 5 0.0079 0.019 0.0189
Trypanosoma cruzi cytochrome P450, putative 0.0032 0.0044 0.0043
Trypanosoma brucei DNA polymerase kappa, putative 0.0021 0.0008 0.0016
Schistosoma mansoni intracisternal A-particle retropepsin (A02 family) 0.124 0.3809 0.3809
Brugia malayi F/Y-rich N-terminus family protein 0.0029 0.0034 0.0033
Entamoeba histolytica calpain large subunit domain III containing protein 0.074 0.2253 0.6419
Echinococcus multilocularis TGF beta signal transducer SmadC 0.0024 0.002 0.0019
Trypanosoma brucei dihydrolipoamide dehydrogenase 0.0034 0.0051 0.011
Schistosoma mansoni cercarial elastase (S01 family) 0.0047 0.0089 0.0089
Loa Loa (eye worm) hypothetical protein 0.0348 0.1029 0.1029
Giardia lamblia Dipeptidyl-peptidase I precursor 0.0285 0.0833 0.2268
Toxoplasma gondii hypothetical protein 0.046 0.1379 0.3758
Leishmania major proteasome beta 6 subunit, putative,20S proteasome beta 6 subunit, putative 0.0066 0.0151 0.0328
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0137 0.0372 0.0371
Schistosoma mansoni RAR-like nuclear receptor 0.0021 0.0009 0.0009
Trypanosoma cruzi calpain cysteine peptidase, putative 0.0681 0.2067 0.2066
Schistosoma mansoni subfamily S1A unassigned peptidase (S01 family) 0.0047 0.0089 0.0089
Onchocerca volvulus 0.0039 0.0064 0.0108
Echinococcus multilocularis diuretic hormone 44 receptor GPRdih2 0.0047 0.009 0.0089
Loa Loa (eye worm) transcriptional regulator 0.0081 0.0197 0.0197
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.0933 0.2853 0.6257
Trichomonas vaginalis Clan CA, family C1, cathepsin B-like cysteine peptidase 0.0285 0.0833 0.2268
Schistosoma mansoni cathepsin F (C01 family) 0.0795 0.2424 0.2424
Brugia malayi Papain family cysteine protease containing protein 0.0285 0.0833 0.0832
Schistosoma mansoni hypothetical protein 0.0047 0.0089 0.0089
Echinococcus granulosus chromobox protein 1 0.007 0.0163 0.0161
Brugia malayi CXXC zinc finger family protein 0.0087 0.0215 0.0214
Echinococcus multilocularis fibrillin 1 0.003 0.0036 0.0035
Trypanosoma cruzi small myristoylated protein 1-1 0.0381 0.113 0.1129
Leishmania major calpain-like protein, putative,cysteine peptidase, Clan CA, family C2, putative 0.0681 0.2067 0.4532
Trypanosoma brucei DNA polymerase IV, putative 0.0021 0.0008 0.0016
Schistosoma mansoni chromatin regulatory protein sir2 0.0363 0.1074 0.1074
Echinococcus granulosus calumenin 0.0176 0.0492 0.0491
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0137 0.0372 0.0371
Leishmania major calpain protease-like protein 0.046 0.1379 0.3023
Brugia malayi MH2 domain containing protein 0.0024 0.002 0.0019
Trichomonas vaginalis calmodulin, putative 0.0172 0.0481 0.131
Giardia lamblia Cathepsin B precursor 0.0285 0.0833 0.2268
Trichomonas vaginalis conserved hypothetical protein 0.0028 0.0031 0.0081
Trypanosoma brucei DNA polymerase IV, putative 0.0021 0.0008 0.0016
Echinococcus multilocularis enteropeptidase 0.0047 0.0089 0.0088
Toxoplasma gondii histone lysine acetyltransferase GCN5-A 0.0043 0.0079 0.0212
Plasmodium vivax serine-repeat antigen (SERA), putative 0.0285 0.0833 0.2256
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.1143 0.3508 0.9564
Brugia malayi chromobox protein homolog 3 0.0039 0.0067 0.0065
Brugia malayi Nuclear hormone receptor family member nhr-41 0.0021 0.0009 0.0008
Brugia malayi Cathepsin L-like precursor 0.1143 0.3508 0.3508
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0285 0.0833 0.2268
Trichomonas vaginalis esterase, putative 0.0039 0.0064 0.0172
Entamoeba histolytica grainin 2 0.02 0.0569 0.1619
Trypanosoma brucei Present in the outer mitochondrial membrane proteome 33 0.0172 0.0481 0.1053
Loa Loa (eye worm) proteasome subunit beta type 1 0.0066 0.0151 0.0151
Loa Loa (eye worm) hypothetical protein 0.0021 0.0009 0.0009
Trypanosoma cruzi calpain-like cysteine peptidase, putative 0.06 0.1814 0.1813
Brugia malayi programmed cell death protein 6 0.0172 0.0481 0.048
Trypanosoma cruzi cysteine peptidase, Clan CA, family C2, putative 0.0681 0.2067 0.2066
Trypanosoma cruzi proteasome beta 6 subunit, putative 0.0066 0.0151 0.015
Echinococcus granulosus Smad4 0.0024 0.002 0.0019
Echinococcus granulosus dna polymerase eta 0.0048 0.0093 0.0092
Trichomonas vaginalis chromobox protein, putative 0.0042 0.0076 0.0204
Wolbachia endosymbiont of Brugia malayi dihydrolipoamide dehydrogenase E3 component 0.0034 0.0051 0.7656
Leishmania major myo-inositol-1(or 4)-monophosphatase 1, putative 0.0039 0.0067 0.0144
Toxoplasma gondii preprocathepsin c precursor, putative 0.0285 0.0833 0.2268
Trichomonas vaginalis Clan CA, family C1, cathepsin L or K-like cysteine peptidase 0.1143 0.3508 0.9564
Loa Loa (eye worm) hypothetical protein 0.0027 0.0027 0.0027
Loa Loa (eye worm) hypothetical protein 0.0047 0.0089 0.0089
Schistosoma mansoni histone-lysine n-methyltransferase suv9 0.0075 0.0176 0.0176
Onchocerca volvulus 0.0039 0.0064 0.0108
Plasmodium vivax hypothetical protein, conserved 0.0176 0.0492 0.1332
Echinococcus granulosus thioredoxin glutathione reductase 0.0099 0.0254 0.0253
Trichomonas vaginalis calmodulin, putative 0.0028 0.0032 0.0083
Onchocerca volvulus Arrow homolog 0.0027 0.0027 0.0035
Entamoeba histolytica cysteine proteinase, putative 0.0633 0.1918 0.5464
Echinococcus multilocularis histone lysine N methyltransferase MLL3 0.0024 0.0018 0.0017
Mycobacterium ulcerans proteasome PrcB 0.015 0.0412 1
Trypanosoma brucei DNA polymerase kappa, putative 0.0021 0.0008 0.0016
Brugia malayi Hypothetical 52.5 kDa protein ZK945.1 in chromosome II, putative 0.0039 0.0064 0.0063
Leishmania major trypanothione reductase 0.0099 0.0254 0.0555
Schistosoma mansoni smad1 5 8 and 0.0024 0.002 0.002
Plasmodium falciparum thioredoxin reductase 0.0099 0.0254 0.0721
Leishmania major cytoskeleton-associated protein CAP5.5, putative,cysteine peptidase, Clan CA, family C2, putative 0.0681 0.2067 0.4532
Toxoplasma gondii kringle domain-containing protein 0.0023 0.0016 0.004
Plasmodium vivax dipeptidyl aminopeptidase 3, putative 0.0285 0.0833 0.2256
Toxoplasma gondii calcium binding protein precursor, putative 0.0028 0.0032 0.0083
Trypanosoma brucei DNA polymerase kappa, putative 0.0021 0.0008 0.0016
Trypanosoma brucei calmodulin, putative 0.0172 0.0481 0.1053
Brugia malayi Nuclear hormone receptor family member nhr-49 0.0021 0.0009 0.0008
Trypanosoma brucei Calpain-like protein CALP1.3 0.0681 0.2067 0.4532
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.074 0.2251 0.4935
Loa Loa (eye worm) intermediate filament protein 0.0055 0.0116 0.0116
Trypanosoma brucei META domain/Domain of unknown function (DUF1935), putative 0.0221 0.0632 0.1383
Echinococcus granulosus histone lysine N methyltransferase MLL3 0.0029 0.0035 0.0034
Trichomonas vaginalis calmodulin, putative 0.0172 0.0481 0.131
Schistosoma mansoni centrin-related 0.0172 0.0481 0.0481
Loa Loa (eye worm) hypothetical protein 0.1143 0.3508 0.3508
Trypanosoma cruzi hypothetical protein, conserved 0.0357 0.1058 0.1057
Leishmania major hypothetical protein, conserved,calpain-like cysteine peptidase, Clan CA, family C2 0.0221 0.0632 0.1383
Loa Loa (eye worm) hypothetical protein 0.2111 0.6527 0.6527
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.08 0.2438 0.5347
Schistosoma mansoni cathepsin S (C01 family) 0.0285 0.0833 0.0833
Toxoplasma gondii proteasome subunit beta type 1, putative 0.0066 0.0151 0.0408
Schistosoma mansoni chromatin regulatory protein sir2 0.0081 0.0197 0.0197
Trypanosoma brucei DNA polymerase kappa, putative 0.0021 0.0008 0.0016
Entamoeba histolytica Sir2 family transcriptional regulator, putative 0.0081 0.0197 0.0558
Schistosoma mansoni cpg binding protein 0.0092 0.0231 0.0231
Echinococcus multilocularis COUP TF:Svp nuclear hormone receptor 0.0021 0.0009 0.0008
Trypanosoma brucei inositol-1(or 4)-monophosphatase 1, putative 0.0039 0.0067 0.0144
Echinococcus granulosus hepatocyte nuclear factor 4 alpha 0.0021 0.0009 0.0008
Plasmodium vivax myosin A tail domain interacting protein MTIP, putative 0.0028 0.0032 0.0083
Schistosoma mansoni matrix metallopeptidase-7 (M10 family) 0.0022 0.0012 0.0012
Echinococcus granulosus NAD dependent deacetylase sirtuin 3 0.0363 0.1074 0.1073
Mycobacterium tuberculosis Probable lipase LipD 0.0039 0.0064 0.0865
Onchocerca volvulus 0.0087 0.0215 0.0405
Echinococcus multilocularis cytoplasmic intermediate filament protein 0.0027 0.0027 0.0026
Trichomonas vaginalis Clan CA, family C1, cathepsin L, S or H-like cysteine peptidase 0.0285 0.0833 0.2268
Entamoeba histolytica hypothetical protein, conserved 0.0176 0.0492 0.14
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0021 0.0009 0.0008
Echinococcus multilocularis neuronal calcium sensor 0.0172 0.0481 0.048
Brugia malayi Matrixin family protein 0.0022 0.0012 0.0011
Entamoeba histolytica cysteine protease, putative 0.0633 0.1918 0.5464
Trichomonas vaginalis chromobox protein, putative 0.007 0.0163 0.044
Loa Loa (eye worm) hypothetical protein 0.0295 0.0864 0.0864
Schistosoma mansoni nuclear hormone receptor nor-1/nor-2 0.0021 0.0009 0.0009
Trypanosoma cruzi kinesin, putative 0.074 0.2253 0.2252
Brugia malayi calpain 5 0.046 0.1379 0.1378
Schistosoma mansoni inositol monophosphatase 0.0039 0.0067 0.0067
Trypanosoma cruzi hypothetical protein, conserved 0.0221 0.0632 0.0631
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.3225 1 1
Echinococcus multilocularis FTZ F1 nuclear receptor protein 0.0021 0.0009 0.0008
Leishmania major calmodulin-like protein 0.0172 0.0481 0.1053
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.1285 0.3951 0.8666
Toxoplasma gondii EFHC1, putative 0.0172 0.0481 0.131
Trypanosoma cruzi cruzipain precursor, putative 0.1285 0.3951 0.3951
Trypanosoma cruzi cysteine peptidase, putative 0.0348 0.1029 0.1028
Brugia malayi hypothetical protein 0.0034 0.0049 0.0048
Trichomonas vaginalis conserved hypothetical protein 0.0028 0.0031 0.0081
Brugia malayi hypothetical protein 0.0041 0.0071 0.007
Trypanosoma brucei hypothetical protein, conserved 0.0172 0.0481 0.1053
Entamoeba histolytica cysteine protease, putative 0.0633 0.1918 0.5464
Trypanosoma brucei Small kinetoplastid calpain-related protein 1-5 0.0221 0.0632 0.1383
Trichomonas vaginalis centrin, putative 0.0172 0.0481 0.131
Trichomonas vaginalis calcium binding protein, putative 0.02 0.0569 0.1548
Schistosoma mansoni ap endonuclease 0.0018 0.0001 0.0001
Leishmania major protein kinase, putative 0.0172 0.0481 0.1053
Trypanosoma cruzi calpain-like cysteine peptidase, putative 0.0681 0.2067 0.2066
Trichomonas vaginalis calpain, putative 0.046 0.1379 0.3758
Giardia lamblia Cathepsin B precursor 0.1195 0.3668 1
Trypanosoma cruzi trypanothione reductase, putative 0.0099 0.0254 0.0253
Leishmania major kinesin, putative 0.074 0.2253 0.4939
Plasmodium vivax dipeptidyl aminopeptidase 2, putative 0.0285 0.0833 0.2256
Plasmodium falciparum transcriptional regulatory protein sir2a 0.0081 0.0197 0.0558
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.1285 0.3951 0.8666
Brugia malayi calpain 7 0.1201 0.3688 0.3687
Brugia malayi ImpB/MucB/SamB family protein 0.0021 0.0008 0.0007
Echinococcus granulosus cathepsin L cysteine protease 0.0633 0.1918 0.1917
Leishmania major 2-oxoglutarate dehydrogenase, e3 component, lipoamidedehydrogenase-like protein 0.0034 0.0051 0.011
Plasmodium falciparum ataxin-2 like protein, putative 0.0052 0.0107 0.0303
Schistosoma mansoni SmCL2-like peptidase (C01 family) 0.0633 0.1918 0.1917
Brugia malayi Heterochromatin protein 1 0.007 0.0163 0.0161
Echinococcus granulosus histone acetyltransferase KAT2B 0.0143 0.039 0.0389
Trypanosoma brucei cysteine peptidase C (CPC) 0.1195 0.3668 0.8045
Schistosoma mansoni SmCL2-like peptidase (C01 family) 0.0633 0.1918 0.1917
Schistosoma mansoni reticulocalbin 0.0176 0.0492 0.0492
Mycobacterium tuberculosis Dihydrolipoamide dehydrogenase LpdC (lipoamide reductase (NADH)) (lipoyl dehydrogenase) (dihydrolipoyl dehydrogenase) (diaphoras 0.0252 0.073 1
Loa Loa (eye worm) latrophilin receptor protein 2 0.0047 0.009 0.009
Trypanosoma brucei calpain, putative 0.046 0.1379 0.3023
Onchocerca volvulus Matrilysin homolog 0.0022 0.0012 0.0005
Echinococcus granulosus dihydrolipoamide dehydrogenase 0.0034 0.0051 0.005
Trypanosoma cruzi trypanothione reductase, putative 0.0034 0.0051 0.005
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0021 0.0009 0.0008
Leishmania major calmodulin-like protein 0.0172 0.0481 0.1053
Brugia malayi Inositol-1 0.0039 0.0067 0.0066
Trypanosoma brucei small myristoylated protein 1-1 0.0381 0.113 0.2477
Brugia malayi cathepsin F-like cysteine proteinase 0.0348 0.1029 0.1028
Loa Loa (eye worm) hypothetical protein 0.0285 0.0833 0.0833
Brugia malayi Steroid receptor seven-up type 2 0.0021 0.0009 0.0008
Brugia malayi Pre-SET motif family protein 0.0429 0.128 0.1279
Entamoeba histolytica cysteine protease, putative 0.0633 0.1918 0.5464
Loa Loa (eye worm) cytoplasmic intermediate filament protein 0.003 0.0036 0.0036
Trypanosoma brucei antigen, putative 0.1201 0.3688 0.8088
Giardia lamblia NAD-dependent histone deacetylase Sir2 0.0295 0.0864 0.2354
Echinococcus granulosus EF hand domain containing family member A2 0.0172 0.0481 0.048
Echinococcus multilocularis laminin 0.003 0.0036 0.0035
Trichomonas vaginalis conserved hypothetical protein 0.0039 0.0067 0.0178
Echinococcus multilocularis histone lysine N methyltransferase MLL3 0.0029 0.0035 0.0034
Loa Loa (eye worm) fibroinase 0.1143 0.3508 0.3508
Loa Loa (eye worm) nuclear hormone receptor family member nhr-40 0.0021 0.0009 0.0009
Echinococcus multilocularis histone lysine methyltransferase setb histone lysine methyltransferase eggless 0.0063 0.0141 0.014
Leishmania major hypothetical protein, conserved 0.0172 0.0481 0.1053
Toxoplasma gondii NADPH-glutathione reductase 0.0034 0.0051 0.0137
Echinococcus granulosus cadherin EGF LAG seven pass G type receptor 0.0047 0.009 0.0089
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0633 0.1918 0.4204
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.1285 0.3951 0.8666
Schistosoma mansoni retinoic acid receptor RXR 0.0021 0.0009 0.0009
Entamoeba histolytica grainin 2 0.0028 0.0032 0.0087
Onchocerca volvulus 0.0022 0.0012 0.0005
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0795 0.2424 0.6607
Loa Loa (eye worm) nuclear hormone receptor family member nhr-49 0.0021 0.0009 0.0009
Loa Loa (eye worm) nuclear hormone receptor family member nhr-41 0.0021 0.0009 0.0009
Brugia malayi Calcium binding EGF domain containing protein 0.003 0.0036 0.0035
Schistosoma mansoni egf-like domain protein 0.0027 0.0027 0.0027
Trypanosoma cruzi myo-inositol-1(or 4)-monophosphatase 1, putative 0.0039 0.0067 0.0066
Trypanosoma cruzi CAMK/CAMKL family protein kinase, putative 0.0172 0.0481 0.048
Trypanosoma cruzi calmodulin, putative 0.0172 0.0481 0.048
Entamoeba histolytica cysteine protease, putative 0.0633 0.1918 0.5464
Echinococcus granulosus GPCR family 2 0.0047 0.009 0.0089
Echinococcus multilocularis terminal deoxycytidyl transferase rev1 0.0021 0.0008 0.0007
Entamoeba histolytica cysteine protease, putative 0.0633 0.1918 0.5464
Mycobacterium ulcerans DNA polymerase IV 0.0021 0.0008 0.0178
Echinococcus granulosus programmed cell death protein 6 0.0032 0.0042 0.0041
Trypanosoma cruzi Present in the outer mitochondrial membrane proteome 33 0.0172 0.0481 0.048
Trypanosoma brucei CAMK/CAMKL family protein kinase, putative 0.0172 0.0481 0.1053
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.1143 0.3508 0.9564
Echinococcus granulosus family C2 unassigned peptidase C02 family 0.3024 0.9373 0.9373
Echinococcus granulosus inositol monophosphatase 1 0.0039 0.0067 0.0066
Giardia lamblia Cathepsin L precursor 0.0285 0.0833 0.2268
Echinococcus granulosus ecdysone induced protein 78C 0.0021 0.0009 0.0008
Trypanosoma brucei cysteine peptidase, Clan CA, family C2, putative 0.0322 0.0949 0.208
Giardia lamblia Cathepsin L precursor 0.0285 0.0833 0.2268
Schistosoma mansoni cercarial elastase (S01 family) 0.0047 0.0089 0.0089
Echinococcus granulosus beta LACTamase domain containing family member 0.0039 0.0064 0.0063
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0031 0.0041 0.0109
Echinococcus granulosus cathepsin l cysteine peptidase 0.1143 0.3508 0.3508
Loa Loa (eye worm) nuclear hormone receptor family member nhr-31 0.0021 0.0009 0.0009
Wolbachia endosymbiont of Brugia malayi dihydrolipoamide dehydrogenase E3 component 0.0034 0.0051 0.7656
Plasmodium vivax dihydrolipoyl dehydrogenase, apicoplast, putative 0.0034 0.0051 0.0136
Schistosoma mansoni aminopeptidase PILS (M01 family) 0.0047 0.0089 0.0089
Trichomonas vaginalis calmodulin, putative 0.0172 0.0481 0.131
Trichomonas vaginalis calcium binding protein, putative 0.0172 0.0481 0.131
Echinococcus granulosus chromatin regulatory protein sir2 0.0363 0.1074 0.1073
Mycobacterium tuberculosis Probable membrane NADH dehydrogenase NdhA 0.0227 0.0651 0.8917
Schistosoma mansoni terminal deoxycytidyl transferase 0.0021 0.0008 0.0008
Leishmania major hypothetical protein, conserved 0.0221 0.0632 0.1383
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.0996 0.305 0.6688
Mycobacterium tuberculosis Probable peptidoglycan hydrolase 0.0027 0.0027 0.035
Loa Loa (eye worm) hypothetical protein 0.0795 0.2424 0.2424
Plasmodium falciparum serine repeat antigen 7 0.0285 0.0833 0.2372
Echinococcus multilocularis EF hand domain containing family member A2 0.0176 0.0492 0.0491
Brugia malayi transcriptional regulator, Sir2 family protein 0.0081 0.0197 0.0196
Trypanosoma brucei centrin-3 0.02 0.0569 0.1246
Leishmania major DNA polymerase kappa, putative,DNA polymerase IV, putative 0.0021 0.0008 0.0016
Loa Loa (eye worm) hypothetical protein 0.0063 0.0141 0.0141
Loa Loa (eye worm) heterochromatin protein 1 0.007 0.0163 0.0163
Trypanosoma cruzi programmed cell death 6 protein-like, putative 0.0172 0.0481 0.048
Giardia lamblia Encystation-specific protease 0.0285 0.0833 0.2268
Trypanosoma cruzi calpain-like cysteine peptidase, putative 0.148 0.456 0.4559
Mycobacterium tuberculosis Possible conserved lipoprotein LpqK 0.0039 0.0064 0.0865
Loa Loa (eye worm) hypothetical protein 0.0039 0.0067 0.0067
Leishmania major hypothetical protein, conserved 0.0221 0.0632 0.1383
Schistosoma mansoni neuronal calcium sensor 0.0172 0.0481 0.0481
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0285 0.0833 0.2268
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0285 0.0833 0.2268
Loa Loa (eye worm) hypothetical protein 0.1651 0.5092 0.5092
Echinococcus granulosus geminin 0.1028 0.3149 0.3148
Echinococcus multilocularis dihydrolipoamide dehydrogenase 0.0034 0.0051 0.005
Plasmodium falciparum serine repeat antigen 6 0.0285 0.0833 0.2372
Echinococcus granulosus calpain A 0.1201 0.3688 0.3687
Trypanosoma brucei DNA polymerase kappa, putative 0.0021 0.0008 0.0016
Schistosoma mansoni reticulocalbin 0.0172 0.0481 0.0481
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.1143 0.3508 0.9564
Loa Loa (eye worm) low-density lipoprotein receptor repeat class B containing protein 0.0027 0.0027 0.0027
Loa Loa (eye worm) trypsin family protein 0.0047 0.0089 0.0089
Onchocerca volvulus 0.0047 0.0089 0.0157
Entamoeba histolytica papain family cysteine protease domain containing protein 0.0285 0.0833 0.2372
Schistosoma mansoni chromatin regulatory protein sir2 0.0363 0.1074 0.1074
Echinococcus multilocularis matrix metallopeptidase 7 (M10 family) 0.0079 0.0191 0.019
Schistosoma mansoni subfamily S1A unassigned peptidase (S01 family) 0.0047 0.0089 0.0089
Brugia malayi Cell death protein 3 precursor 0.0058 0.0125 0.0124
Brugia malayi calcium-binding protein 0.0172 0.0481 0.048
Loa Loa (eye worm) hypothetical protein 0.0028 0.0032 0.0032
Onchocerca volvulus 0.0488 0.1464 0.2863
Entamoeba histolytica cysteine proteinase, putative 0.1143 0.3508 1
Brugia malayi Cathepsin L-like precursor 0.1143 0.3508 0.3508
Trypanosoma cruzi calmodulin, putative 0.0172 0.0481 0.048
Echinococcus granulosus apoptotic protease activating factor 1 0.0041 0.0071 0.007
Schistosoma mansoni hypothetical protein 0.0047 0.009 0.009
Schistosoma mansoni hypothetical protein 0.0135 0.0364 0.0364
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.0662 0.2008 0.4402
Trichomonas vaginalis calpain, putative 0.046 0.1379 0.3758
Brugia malayi EF hand family protein 0.0176 0.0492 0.0491
Brugia malayi cathepsin L-like cysteine proteinase 0.0285 0.0833 0.0832
Trypanosoma cruzi cytoskeleton-associated protein CAP5.5, putative 0.0681 0.2067 0.2066
Trypanosoma cruzi hypothetical protein, conserved 0.0221 0.0632 0.0631
Brugia malayi Cathepsin L-like cysteine proteinase 0.0795 0.2424 0.2423
Trypanosoma cruzi cysteine peptidase C (CPC), putative 0.3225 1 1
Trypanosoma cruzi calpain-like cysteine peptidase, putative 0.0595 0.1798 0.1797
Onchocerca volvulus 0.0172 0.0481 0.0929
Trichomonas vaginalis Clan CA, family C1, cathepsin L or K-like cysteine peptidase 0.1143 0.3508 0.9564
Schistosoma mansoni thyroid hormone receptor 0.0156 0.043 0.043
Trichomonas vaginalis hypothetical protein 0.046 0.1379 0.3758
Leishmania major cathepsin L-like protease 0.1285 0.3951 0.8666
Echinococcus granulosus calpain 0.1201 0.3688 0.3687
Echinococcus granulosus cathepsin b 0.3225 1 1
Loa Loa (eye worm) CXXC zinc finger family protein 0.0087 0.0215 0.0215
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.0815 0.2486 0.5451
Loa Loa (eye worm) MH2 domain-containing protein 0.0024 0.002 0.002
Trypanosoma cruzi DNA polymerase kappa, putative 0.0021 0.0008 0.0007
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.0834 0.2545 0.5581
Brugia malayi Proteasome A-type and B-type family protein 0.015 0.0412 0.0411
Schistosoma mansoni family C2 unassigned peptidase (C02 family) 0.3024 0.9373 0.9373
Giardia lamblia Sirtuin type 2 0.0081 0.0197 0.0534
Echinococcus granulosus calpain A 0.3028 0.9383 0.9383
Schistosoma mansoni DNA polymerase eta 0.0048 0.0093 0.0093
Giardia lamblia Hypothetical protein 0.0285 0.0833 0.2268
Trypanosoma brucei SIR2-like protein 4, putative 0.0081 0.0197 0.0429
Toxoplasma gondii proteasome subunit beta type, putative 0.015 0.0412 0.112
Onchocerca volvulus 0.1143 0.3508 0.6885
Echinococcus granulosus calpain 5 0.1201 0.3688 0.3687
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0034 0.0051 0.005
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0285 0.0833 0.2268
Schistosoma mansoni photoreceptor-specific nuclear receptor related 0.0021 0.0009 0.0009
Echinococcus multilocularis cathepsin L cysteine protease 0.1143 0.3508 0.3508
Onchocerca volvulus 0.1143 0.3508 0.6885
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.0285 0.0833 0.0833
Giardia lamblia DINP protein human, muc B family 0.0021 0.0008 0.002
Plasmodium falciparum ataxin-2 like protein, putative 0.0052 0.0107 0.0303
Leishmania major cathepsin L-like protease 0.1143 0.3508 0.7694
Echinococcus multilocularis chromobox protein 1 0.007 0.0163 0.0161
Trypanosoma cruzi calpain-like cysteine peptidase, putative 0.1201 0.3688 0.3687
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.1143 0.3508 0.9564
Trichomonas vaginalis calcium binding protein, putative 0.0172 0.0481 0.131
Onchocerca volvulus 0.0176 0.0492 0.095
Loa Loa (eye worm) steroid hormone receptor 0.0021 0.0009 0.0009
Entamoeba histolytica protein kinase, putative 0.074 0.2253 0.6419
Plasmodium vivax serine-repeat antigen (SERA) 0.0285 0.0833 0.2256
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0285 0.0833 0.2268
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.1042 0.3194 0.7003
Trypanosoma brucei Calpain-like protein 1.1 0.1042 0.3194 0.7003
Trichomonas vaginalis conserved hypothetical protein 0.0285 0.0833 0.2268
Onchocerca volvulus 0.0028 0.0032 0.0044
Toxoplasma gondii ABC1 family protein 0.0039 0.0064 0.0172
Echinococcus multilocularis cathepsin L 0.0633 0.1918 0.1917
Schistosoma mansoni hypothetical protein 0.1028 0.3149 0.3148
Schistosoma mansoni cercarial elastase (S01 family) 0.0047 0.0089 0.0089
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0031 0.0041 0.0109
Schistosoma mansoni Smad4 0.0024 0.002 0.002
Echinococcus multilocularis cathepsin b 0.3225 1 1
Leishmania major hypothetical protein, conserved 0.0221 0.0632 0.1383
Plasmodium falciparum glutathione reductase 0.0099 0.0254 0.0721
Brugia malayi cathepsin Z-like cysteine proteinase 0.0285 0.0833 0.0832
Echinococcus multilocularis musashi 0.0055 0.0116 0.0115
Brugia malayi Copper type II ascorbate-dependent monooxygenase, C-terminal domain containing protein 0.0128 0.0342 0.0341
Echinococcus granulosus cpg binding protein 0.0092 0.0231 0.023
Trichomonas vaginalis chromatin regulatory protein sir2, putative 0.0081 0.0197 0.0534
Trypanosoma cruzi centrin-3 0.02 0.0569 0.0568
Trypanosoma cruzi cysteine peptidase, Clan CA, family C2, putative 0.0834 0.2545 0.2544
Entamoeba histolytica cysteine protease, putative 0.0633 0.1918 0.5464
Echinococcus granulosus tachykinin peptides receptor 99D 0.0596 0.1803 0.1802
Mycobacterium ulcerans hypothetical protein 0.0039 0.0064 0.1536
Echinococcus granulosus neurocalcin 0.0172 0.0481 0.048
Brugia malayi Cathepsin L-like precursor 0.0795 0.2424 0.2423
Brugia malayi Nuclear hormone receptor family member nhr-3 0.0021 0.0009 0.0008
Toxoplasma gondii centrin 0.0172 0.0481 0.131
Brugia malayi Kringle domain containing protein 0.0023 0.0016 0.0015
Toxoplasma gondii cathepsin B 0.1195 0.3668 1
Brugia malayi Corticotropin releasing factor receptor 2 precursor, putative 0.0148 0.0407 0.0406
Entamoeba histolytica cysteine proteinase 1, putative 0.0633 0.1918 0.5464
Schistosoma mansoni cathepsin C 0.0285 0.0833 0.0833
Echinococcus granulosus lamin dm0 0.0055 0.0116 0.0115
Plasmodium vivax ataxin-2 like protein, putative 0.0052 0.0107 0.0288
Brugia malayi calpain 5 0.074 0.2253 0.2252
Loa Loa (eye worm) AStacin protease 0.0057 0.0123 0.0123
Echinococcus granulosus EF hand domain containing family member A2 0.0176 0.0492 0.0491
Trypanosoma brucei hypothetical protein 0.074 0.2251 0.4935
Trypanosoma cruzi cysteine peptidase, putative 0.1143 0.3508 0.3508
Echinococcus granulosus programmed cell death protein 0.02 0.0569 0.0568
Leishmania major calcineurin B subunit, putative 0.0172 0.0481 0.1053
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.1042 0.3194 0.7003
Schistosoma mansoni hypothetical protein 0.0023 0.0017 0.0017
Loa Loa (eye worm) TK/ROR protein kinase 0.0023 0.0016 0.0016
Mycobacterium tuberculosis Possible DNA-damage-inducible protein P DinP (DNA polymerase V) (pol IV 2) (DNA nucleotidyltransferase (DNA-directed)) 0.0021 0.0008 0.01
Trypanosoma brucei calpain-like cysteine peptidase, putative 0.028 0.0816 0.1787
Loa Loa (eye worm) calpain 0.1201 0.3688 0.3688
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0633 0.1918 0.4204
Schistosoma mansoni steroid hormone receptor ad4bp 0.0021 0.0009 0.0009
Entamoeba histolytica cysteine protease, putative 0.0285 0.0833 0.2372
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0034 0.0051 0.005
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.1143 0.3508 0.9564
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.3225 1 1
Schistosoma mansoni dipeptidyl-peptidase I (C01 family) 0.0285 0.0833 0.0833
Trypanosoma brucei proteasome subunit beta type-5, putative 0.015 0.0412 0.0901
Plasmodium falciparum centrin-1 0.0172 0.0481 0.1369
Mycobacterium ulcerans flavoprotein disulfide reductase 0.0034 0.0051 0.1225
Loa Loa (eye worm) hypothetical protein 0.0228 0.0656 0.0656
Leishmania major hypothetical protein, conserved 0.0023 0.0016 0.0032
Echinococcus multilocularis calpain 5 0.1201 0.3688 0.3687
Mycobacterium ulcerans fusion of enoyl-CoA hydratase, EchA21 and lipase, LipE 0.0039 0.0064 0.1536
Loa Loa (eye worm) hypothetical protein 0.0348 0.1029 0.1029
Brugia malayi calcium-independent alpha-latrotoxin receptor 2, putative 0.0047 0.009 0.0089
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0187 0.0527 0.0526
Echinococcus granulosus retinoic acid receptor rxr beta a 0.0021 0.0009 0.0008
Loa Loa (eye worm) multiple epidermal growth factor-like domains 6 0.003 0.0036 0.0036
Trichomonas vaginalis chromatin regulatory protein sir2, putative 0.0081 0.0197 0.0534
Schistosoma mansoni calpain-2 (C02 family) 0.046 0.1379 0.1379
Brugia malayi Papain family cysteine protease containing protein 0.0285 0.0833 0.0832
Trichomonas vaginalis DNA helicase recq1, putative 0.0023 0.0015 0.0038
Trypanosoma brucei cytoskeleton-associated protein CAP5.5, putative 0.0681 0.2067 0.4532
Mycobacterium leprae possible inositol monophosphatase SubH (IMPase) (inositol-1-phosphatase) (I-1-Pase ). 0.0035 0.0054 0.0388
Echinococcus multilocularis transmembrane protease serine 3 0.0047 0.0089 0.0088
Echinococcus granulosus peptidyl glycine alpha amidating monooxygenase 0.024 0.0693 0.0692
Trypanosoma cruzi proteasome subunit beta type-5, putative 0.015 0.0412 0.0411
Trypanosoma brucei hypothetical protein, conserved 0.0357 0.1058 0.2319
Loa Loa (eye worm) hypothetical protein 0.0022 0.0012 0.0012
Trypanosoma cruzi DNA polymerase kappa, putative 0.0021 0.0008 0.0007
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0137 0.0372 0.0371
Leishmania major hypothetical protein, conserved 0.0221 0.0632 0.1383
Echinococcus granulosus mothers against decapentaplegic 5 0.0024 0.002 0.0019
Plasmodium vivax serine-repeat antigen 5 (SERA) 0.0285 0.0833 0.2256
Plasmodium falciparum calpain 0.046 0.1379 0.3929
Schistosoma mansoni calpain-7 (C02 family) 0.1201 0.3688 0.3688
Echinococcus granulosus Mastin 0.0047 0.0089 0.0088
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0031 0.0041 0.0109
Brugia malayi Cathepsin L-like precursor 0.0795 0.2424 0.2423
Trypanosoma brucei Silent information regulator 2 related protein 3 0.0081 0.0197 0.0429
Brugia malayi hypothetical protein 0.0228 0.0656 0.0655
Echinococcus granulosus diuretic hormone 44 receptor GPRdih2 0.0047 0.009 0.0089
Entamoeba histolytica cysteine protease, putative 0.1143 0.3508 1
Trichomonas vaginalis calcium binding protein, putative 0.0172 0.0481 0.131
Brugia malayi Trypsin family protein 0.0047 0.0089 0.0088
Trypanosoma brucei cysteine peptidase, Clan CA, family C2, putative 0.046 0.1379 0.3023
Schistosoma mansoni calpain C (C02 family) 0.1201 0.3688 0.3688
Schistosoma mansoni peptidyl-glycine monooxygenase 0.024 0.0693 0.0693
Schistosoma mansoni inositol monophosphatase 0.0039 0.0067 0.0067
Schistosoma mansoni chromatin regulatory protein sir2 0.0363 0.1074 0.1074
Leishmania major receptor-type adenylate cyclase a-like protein 0.0221 0.0632 0.1383
Schistosoma mansoni cercarial elastase (S01 family) 0.0047 0.0089 0.0089
Loa Loa (eye worm) hypothetical protein 0.0795 0.2424 0.2424
Echinococcus multilocularis programmed cell death protein 0.02 0.0569 0.0568
Mycobacterium ulcerans NAD-dependent deacetylase 0.0081 0.0197 0.4768
Schistosoma mansoni rab 0.0172 0.0481 0.0481
Onchocerca volvulus 0.0148 0.0405 0.0779
Trichomonas vaginalis Clan CA, family C1, cathepsin L or H-like cysteine peptidase 0.0285 0.0833 0.2268
Brugia malayi Thioredoxin reductase 0.0099 0.0254 0.0253
Loa Loa (eye worm) hypothetical protein 0.0039 0.0064 0.0064
Trypanosoma cruzi hypothetical protein, conserved 0.0028 0.0032 0.003
Trichomonas vaginalis conserved hypothetical protein 0.0039 0.0067 0.0178
Trypanosoma cruzi cysteine peptidase, Clan CA, family C2, putative 0.1402 0.4316 0.4316
Trypanosoma cruzi conserved protein 0.069 0.2096 0.2095
Loa Loa (eye worm) hypothetical protein 0.0285 0.0833 0.0833
Trichomonas vaginalis myo inositol monophosphatase, putative 0.0039 0.0067 0.0179
Loa Loa (eye worm) myosin Light Chain family member 0.0032 0.0042 0.0042
Schistosoma mansoni hypothetical protein 0.0102 0.026 0.026
Schistosoma mansoni survival motor neuron protein 0.0047 0.0089 0.0089
Trypanosoma brucei Silent information regulator 2 related protein 1 0.0363 0.1074 0.2354
Echinococcus granulosus cathepsin L cysteine proteinase 0.1143 0.3508 0.3508
Echinococcus multilocularis proteasome (prosome, macropain) subunit, beta 0.0066 0.0151 0.015
Trypanosoma cruzi Domain of unknown function (DUF1935), putative 0.0221 0.0632 0.0631
Schistosoma mansoni smad1 5 8 and 0.0024 0.002 0.002
Mycobacterium tuberculosis Conserved hypothetical protein 0.0021 0.0008 0.01
Plasmodium vivax centrin-1, putative 0.0172 0.0481 0.1303
Trypanosoma cruzi cysteine proteinase, putative 0.0633 0.1918 0.1917
Brugia malayi cahepsin L-like non-peptiedase homolog 0.0285 0.0833 0.0832
Onchocerca volvulus 0.0075 0.0176 0.0329
Brugia malayi MH2 domain containing protein 0.0024 0.002 0.0019
Trypanosoma cruzi mitochondrial calcium uptake 1, putative 0.0172 0.0481 0.048
Schistosoma mansoni hypothetical protein 0.046 0.1379 0.1379
Brugia malayi hypothetical protein 0.0148 0.0405 0.0404
Echinococcus multilocularis NAD dependent deacetylase sirtuin 3 0.0363 0.1074 0.1073
Schistosoma mansoni chromatin regulatory protein sir2 0.0081 0.0197 0.0197
Trypanosoma cruzi cytoskeleton-associated protein CAP5.5, putative 0.0681 0.2067 0.2066
Plasmodium vivax proteasome subunit beta type-1, putative 0.0066 0.0151 0.0406
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0034 0.0051 0.005
Trichomonas vaginalis myo inositol monophosphatase, putative 0.0039 0.0067 0.0179
Echinococcus granulosus cathepsin L 0.0633 0.1918 0.1917
Trypanosoma cruzi Domain of unknown function (DUF1935), putative 0.0221 0.0632 0.0631
Loa Loa (eye worm) hypothetical protein 0.0172 0.0481 0.0481
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.1143 0.3508 0.9564
Entamoeba histolytica cysteine protease, putative 0.0285 0.0833 0.2372
Echinococcus granulosus smad 0.0024 0.002 0.0019
Echinococcus multilocularis dna polymerase eta 0.0048 0.0093 0.0092
Plasmodium vivax proteasome subunit beta type-5, putative 0.015 0.0412 0.1114
Echinococcus multilocularis GPCR, family 2 0.0047 0.009 0.0089
Brugia malayi proteasome subunit beta type 1 0.0066 0.0151 0.015
Plasmodium vivax unspecified product 0.0285 0.0833 0.2256
Trypanosoma brucei DNA polymerase kappa, putative 0.0021 0.0008 0.0016
Echinococcus multilocularis Myosin regulatory light chain 0.0028 0.0032 0.003
Echinococcus granulosus cathepsin l1 0.0795 0.2424 0.2423
Brugia malayi calpain family protein 1 0.2852 0.8835 0.8835
Toxoplasma gondii inositol(myo)-1(or 4)-monophosphatase 2, putative 0.0039 0.0067 0.0179
Echinococcus multilocularis cysteine protease 0.1143 0.3508 0.3508
Loa Loa (eye worm) nuclear hormone receptor family member nhr-1 0.0021 0.0009 0.0009
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0039 0.0064 0.0064
Schistosoma mansoni lamin 0.0055 0.0116 0.0116
Brugia malayi Cathepsin L-like precursor 0.1143 0.3508 0.3508
Plasmodium vivax serine-repeat antigen (SERA) 0.0285 0.0833 0.2256
Echinococcus multilocularis cathepsin L 0.0285 0.0833 0.0832
Echinococcus granulosus NAD dependent deacetylase sirtuin 6 0.0081 0.0197 0.0196
Schistosoma mansoni neuronal calcium sensor 0.0172 0.0481 0.0481
Onchocerca volvulus 0.0047 0.0089 0.0157
Entamoeba histolytica proteasome subunit beta type 5 precursor, putative 0.015 0.0412 0.1171
Onchocerca volvulus 0.1143 0.3508 0.6885
Echinococcus granulosus mixed lineage leukemia protein mll 0.0024 0.0018 0.0017
Brugia malayi Calmodulin-like protein 0.0172 0.0481 0.048
Brugia malayi Nuclear hormone receptor-like 1 0.0021 0.0009 0.0008
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.1285 0.3951 0.8666
Brugia malayi cathepsin F-like cysteine proteinase 0.0285 0.0833 0.0832
Leishmania major i/6 autoantigen-like protein 0.0172 0.0481 0.1053
Echinococcus multilocularis calbindin 32 0.0176 0.0492 0.0491
Trypanosoma brucei variant surface glycoprotein (VSG), putative 0.028 0.0816 0.1787
Brugia malayi nuclear receptor NHR-88 0.0021 0.0009 0.0008
Trypanosoma cruzi I/6 autoantigen, putative 0.0172 0.0481 0.048
Chlamydia trachomatis dihydrolipoyl dehydrogenase 0.0034 0.0051 0.5
Mycobacterium tuberculosis Probable esterase/lipase LipP 0.0039 0.0064 0.0865
Echinococcus multilocularis mixed lineage leukemia protein mll 0.0024 0.0018 0.0017
Trichomonas vaginalis calmodulin, putative 0.0172 0.0481 0.131
Giardia lamblia Cysteine protease 0.0285 0.0833 0.2268
Brugia malayi Latrophilin receptor protein 2 0.0047 0.009 0.0089
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0633 0.1918 0.5226
Toxoplasma gondii histone lysine methyltransferase SET1 0.0171 0.0476 0.1296
Plasmodium falciparum serine repeat antigen 5 0.0285 0.0833 0.2372
Trypanosoma brucei calpain-like protein, putative 0.148 0.456 1
Brugia malayi Hemopexin family protein 0.0031 0.004 0.0039
Giardia lamblia Cathepsin L-like protease 0.0285 0.0833 0.2268
Plasmodium falciparum proteasome subunit beta type-5 0.015 0.0412 0.1171
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.1042 0.3194 0.7003
Trichomonas vaginalis centrin, putative 0.0028 0.0032 0.0083
Trichomonas vaginalis chromatin regulatory protein sir2, putative 0.0081 0.0197 0.0534
Plasmodium vivax vivapain-1 0.0633 0.1918 0.5198
Onchocerca volvulus Cathepsin L homolog 0.1143 0.3508 0.6885
Plasmodium falciparum serine repeat antigen 8 0.0285 0.0833 0.2372
Trypanosoma brucei DNA polymerase kappa, putative 0.0021 0.0008 0.0016
Echinococcus granulosus proteasome prosome macropain 0.015 0.0412 0.0411
Echinococcus granulosus lamin 0.0055 0.0116 0.0115
Plasmodium vivax calcium-dependent protein kinase 3, putative 0.0172 0.0481 0.1303
Trichomonas vaginalis helicase, putative 0.002 0.0005 0.0012
Loa Loa (eye worm) hypothetical protein 0.0023 0.0016 0.0016
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0285 0.0833 0.2268
Trypanosoma cruzi cysteine protease, putative 0.0633 0.1918 0.1917
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0137 0.0372 0.0371
Trypanosoma cruzi small myristoylated protein 1-2 0.0381 0.113 0.1129
Leishmania major cathepsin L-like protease 0.1143 0.3508 0.7694
Trypanosoma cruzi calpain-like cysteine peptidase, putative 0.148 0.456 0.4559
Echinococcus granulosus Myosin regulatory light chain 0.0028 0.0032 0.003
Schistosoma mansoni nuclear receptor 2DBD-gamma 0.0021 0.0009 0.0009
Loa Loa (eye worm) hypothetical protein 0.034 0.1003 0.1003
Brugia malayi Fibulin-1 precursor 0.003 0.0036 0.0035
Onchocerca volvulus 0.0047 0.0089 0.0157
Leishmania major silent information regulator 2, putative 0.0363 0.1074 0.2354
Mycobacterium tuberculosis Probable dehydrogenase 0.0227 0.0651 0.8917
Plasmodium falciparum dipeptidyl aminopeptidase 1 0.0285 0.0833 0.2372
Loa Loa (eye worm) hypothetical protein 0.2852 0.8835 0.8835
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0285 0.0833 0.2268
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0285 0.0833 0.2268
Plasmodium falciparum dipeptidyl aminopeptidase 3 0.0285 0.0833 0.2372
Mycobacterium leprae DIHYDROLIPOAMIDE DEHYDROGENASE LPD (LIPOAMIDE REDUCTASE (NADH)) (LIPOYL DEHYDROGENASE) (DIHYDROLIPOYL DEHYDROGENASE) (DIAPHORASE 0.0252 0.073 1
Onchocerca volvulus 0.1143 0.3508 0.6885
Echinococcus multilocularis programmed cell death protein 0.02 0.0569 0.0568
Entamoeba histolytica calmodulin, putative 0.0172 0.0481 0.1369
Schistosoma mansoni neuronal calcium sensor 0.0172 0.0481 0.0481
Mycobacterium tuberculosis Transcriptional regulatory protein 0.0081 0.0197 0.2685
Leishmania major programmed cell death 6 protein-like protein 0.0172 0.0481 0.1053
Echinococcus granulosus COUP TF:Svp nuclear hormone receptor 0.0021 0.0009 0.0008
Schistosoma mansoni hypothetical protein 0.0023 0.0016 0.0016
Toxoplasma gondii histone lysine methyltransferase SET/SUV39 0.0063 0.0141 0.0381
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.1143 0.3508 0.9564
Echinococcus multilocularis EF hand domain containing family member A2 0.0172 0.0481 0.048
Toxoplasma gondii calmodulin CAM1 0.0176 0.0492 0.1339
Schistosoma mansoni caspase-7 (C14 family) 0.0058 0.0125 0.0125
Trichomonas vaginalis Family T1, proteasome beta subunit, threonine peptidase 0.0066 0.0151 0.0408
Giardia lamblia Proteasome subunit beta type 5 precursor 0.015 0.0412 0.112
Loa Loa (eye worm) transcription factor SMAD2 0.0357 0.1058 0.1058
Leishmania major cathepsin L-like protease 0.1285 0.3951 0.8666
Entamoeba histolytica EF-hand calcium-binding domain containing protein 0.0172 0.0481 0.1369
Echinococcus granulosus Nuclear hormone receptor family member nhr 41 0.0021 0.0009 0.0008
Schistosoma mansoni rab geranylgeranyl transferase alpha subunit 0.0021 0.0008 0.0008
Leishmania major hypothetical protein, conserved 0.0357 0.1058 0.2319
Trypanosoma brucei conserved protein 0.023 0.0661 0.1448
Echinococcus multilocularis cathepsin b 0.3225 1 1
Echinococcus multilocularis inositol monophosphatase 1 0.0039 0.0067 0.0066
Trichomonas vaginalis calmodulin, putative 0.0172 0.0481 0.131
Plasmodium falciparum dihydrolipoyl dehydrogenase, mitochondrial 0.0034 0.0051 0.0143
Plasmodium vivax serine-repeat antigen 2 (SERA) 0.0285 0.0833 0.2256
Leishmania major calpain, putative,cysteine peptidase, Clan CA, family C2, putative 0.1201 0.3688 0.8088
Trypanosoma brucei dihydrolipoamide dehydrogenase 0.0034 0.0051 0.011
Brugia malayi Calcitonin receptor-like protein seb-1 0.0148 0.0407 0.0406
Plasmodium falciparum cysteine proteinase falcipain 1 0.0633 0.1918 0.5464
Trichomonas vaginalis mercuric reductase, putative 0.0034 0.0051 0.0137
Giardia lamblia Cathepsin L precursor 0.0285 0.0833 0.2268
Trichomonas vaginalis Clan CA, family C2, calpain-like cysteine peptidase 0.046 0.1379 0.3758
Loa Loa (eye worm) papain family cysteine protease containing protein 0.0285 0.0833 0.0833
Schistosoma mansoni cercarial elastase (S01 family) 0.0047 0.0089 0.0089
Trypanosoma cruzi cysteine peptidase, Clan CA, family C2, putative 0.1201 0.3688 0.3687
Trypanosoma cruzi proteasome beta 6 subunit, putative 0.0066 0.0151 0.015
Trichomonas vaginalis myosin light chain 1, putative 0.0172 0.0481 0.131
Mycobacterium tuberculosis Possible penicillin-binding protein 0.0246 0.0712 0.9751
Brugia malayi calpain D 0.046 0.1379 0.1378
Trichomonas vaginalis chromatin regulatory protein sir2, putative 0.0081 0.0197 0.0534
Schistosoma mansoni ap endonuclease 0.0018 0.0001 0.0001
Entamoeba histolytica cysteine protease, putative 0.0285 0.0833 0.2372
Schistosoma mansoni retinoid-x-receptor (RXR) 0.0021 0.0009 0.0009
Mycobacterium leprae proteasome (beta subunit) PrcB 0.015 0.0412 0.5473
Entamoeba histolytica cysteine proteinase, putative 0.0633 0.1918 0.5464
Echinococcus granulosus Tolloid protein 1 0.0092 0.023 0.0229
Trichomonas vaginalis conserved hypothetical protein 0.002 0.0005 0.0012
Echinococcus granulosus histone lysine N methyltransferase MLL3 0.0024 0.0018 0.0017
Leishmania major centrin, putative 0.0172 0.0481 0.1053
Echinococcus granulosus sarcoplasmic calcium binding protein 0.0172 0.0481 0.048
Echinococcus granulosus enteropeptidase 0.0047 0.0089 0.0088
Loa Loa (eye worm) calpain family protein 1 0.2852 0.8835 0.8835
Plasmodium falciparum serine repeat antigen 3 0.0285 0.0833 0.2372
Loa Loa (eye worm) nuclear hormone receptor family member nhr-14 0.0021 0.0009 0.0009
Trypanosoma brucei unspecified product 0.0221 0.0632 0.1383
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.1143 0.3508 0.9564
Onchocerca volvulus Heterochromatin protein 1 homolog 0.0039 0.0067 0.0112
Loa Loa (eye worm) proteasome A-type and B-type family protein 0.015 0.0412 0.0412
Echinococcus multilocularis neurocalcin 0.0172 0.0481 0.048
Loa Loa (eye worm) inositol-1 0.0039 0.0067 0.0067
Schistosoma mansoni family C2 unassigned peptidase (C02 family) 0.2852 0.8835 0.8835
Echinococcus multilocularis dna polymerase kappa 0.0021 0.0008 0.0007
Loa Loa (eye worm) glutathione reductase 0.0099 0.0254 0.0254
Giardia lamblia Cathepsin B precursor 0.0285 0.0833 0.2268
Schistosoma mansoni chromobox protein 0.007 0.0163 0.0162
Trichomonas vaginalis Clan CA, family C1, cathepsin B-like cysteine peptidase 0.0285 0.0833 0.2268
Brugia malayi GTP-binding regulatory protein Gs alpha-S chain, putative 0.0137 0.0372 0.0371
Schistosoma mansoni hypothetical protein 0.0047 0.0089 0.0089
Loa Loa (eye worm) hypothetical protein 0.0039 0.0064 0.0064
Trypanosoma brucei calpain, putative 0.074 0.2251 0.4935
Trypanosoma cruzi hypothetical protein, conserved 0.0039 0.0064 0.0063
Plasmodium falciparum serine repeat antigen 2 0.0285 0.0833 0.2372
Giardia lamblia Hypothetical protein 0.0176 0.0492 0.1339
Brugia malayi Matrixin family protein 0.0022 0.0012 0.0011
Trichomonas vaginalis Clan CA, family C2, calpain-like cysteine peptidase 0.046 0.1379 0.3758
Loa Loa (eye worm) programmed cell death protein 6 0.0176 0.0492 0.0492
Echinococcus granulosus dnaJ subfamily B 0.0814 0.2483 0.2482
Plasmodium falciparum dipeptidyl aminopeptidase 2 0.0285 0.0833 0.2372
Trypanosoma cruzi proteasome subunit beta type-5, putative 0.015 0.0412 0.0411
Leishmania major acetoin dehydrogenase e3 component-like protein 0.0034 0.0051 0.011
Loa Loa (eye worm) CYP4Cod1 0.0032 0.0044 0.0044
Leishmania major hypothetical protein, conserved 0.069 0.2096 0.4597
Trypanosoma brucei PAB1-binding protein , putative 0.0052 0.0107 0.0233
Brugia malayi latrophilin 2 splice variant baaae 0.0102 0.026 0.0259
Plasmodium vivax serine-repeat antigen 3 (SERA) 0.0285 0.0833 0.2256
Loa Loa (eye worm) hypothetical protein 0.0148 0.0405 0.0405
Trypanosoma brucei hypothetical protein, conserved 0.0039 0.0064 0.0138
Brugia malayi Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain containing protein 0.0025 0.0023 0.0022
Echinococcus granulosus cysteine protease 0.0633 0.1918 0.1917
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0039 0.0064 0.0064
Schistosoma mansoni cathepsin B (C01 family) 0.0285 0.0833 0.0833
Brugia malayi Trypsin family protein 0.0047 0.0089 0.0088
Loa Loa (eye worm) ImpB/MucB/SamB family protein 0.0021 0.0008 0.0008
Trypanosoma brucei mitochondrial calcium uptake 1 0.0172 0.0481 0.1053
Giardia lamblia Cathepsin L precursor 0.0285 0.0833 0.2268
Brugia malayi ecdysteroid receptor 0.0021 0.0009 0.0008
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.1143 0.3508 0.9564
Trypanosoma brucei calmodulin, putative 0.0176 0.0492 0.1077
Echinococcus multilocularis calcyphosin protein 0.0028 0.0032 0.003
Schistosoma mansoni neuronal calcium sensor 0.0172 0.0481 0.0481
Entamoeba histolytica Sir2 family transcriptional regulator, putative 0.0363 0.1074 0.306
Echinococcus multilocularis Mastin 0.0047 0.0089 0.0088
Loa Loa (eye worm) hypothetical protein 0.0052 0.0107 0.0107
Trichomonas vaginalis caltractin, putative 0.0028 0.0032 0.0083
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0137 0.0372 0.0371
Trypanosoma brucei calpain-like cysteine peptidase, putative 0.148 0.456 1
Trichomonas vaginalis bollus pemphigoid antigen, putative 0.0028 0.0032 0.0083
Entamoeba histolytica cysteine proteinase, putative 0.0633 0.1918 0.5464
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0021 0.0008 0.0019
Entamoeba histolytica cysteine protease, putative 0.0633 0.1918 0.5464
Echinococcus granulosus Calcium binding protein 0.0028 0.0032 0.003
Brugia malayi Papain family cysteine protease containing protein 0.1143 0.3508 0.3508
Trypanosoma cruzi cytoskeleton-associated protein CAP5.5, putative 0.0681 0.2067 0.2066
Trypanosoma cruzi cysteine peptidase, Clan CA, family C2, putative 0.148 0.456 0.4559
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.1143 0.3508 0.9564
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.1143 0.3508 0.9564
Schistosoma mansoni calpain-7 (C02 family) 0.1201 0.3688 0.3688
Loa Loa (eye worm) hypothetical protein 0.0027 0.0027 0.0027
Trypanosoma cruzi cysteine peptidase, Clan CA, family C2, putative 0.1042 0.3194 0.3193
Loa Loa (eye worm) hypothetical protein 0.0348 0.1029 0.1029
Plasmodium falciparum ADP-dependent DNA helicase RecQ 0.002 0.0007 0.0016
Entamoeba histolytica hypothetical protein 0.0285 0.0833 0.2372
Giardia lamblia Cathepsin B precursor 0.0285 0.0833 0.2268
Echinococcus multilocularis FTZ F1 alpha 0.0021 0.0009 0.0008
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0034 0.0051 0.005
Leishmania major hypothetical protein, conserved 0.0052 0.0107 0.0233
Schistosoma mansoni hypothetical protein 0.0172 0.0481 0.0481
Schistosoma mansoni hypothetical protein 0.0047 0.009 0.009
Loa Loa (eye worm) hypothetical protein 0.0039 0.0064 0.0064
Entamoeba histolytica cysteine protease, putative 0.0633 0.1918 0.5464
Trypanosoma brucei cysteine peptidase, putative 0.0681 0.2067 0.4532
Trichomonas vaginalis inositol monophosphatase, putative 0.0039 0.0067 0.0179
Mycobacterium ulcerans dihydrolipoamide dehydrogenase 0.0034 0.0051 0.1225
Trypanosoma cruzi cysteine peptidase, Clan CA, family C2, putative 0.0662 0.2008 0.2007
Brugia malayi Cathepsin L-like precursor 0.0348 0.1029 0.1028
Echinococcus multilocularis glycoprotein Antigen 5 0.0047 0.0089 0.0088
Leishmania major cathepsin L-like protease 0.1143 0.3508 0.7694
Onchocerca volvulus 0.0047 0.0089 0.0157
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.1143 0.3508 0.9564
Echinococcus multilocularis cpg binding protein 0.0092 0.0231 0.023
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0021 0.0009 0.0008
Echinococcus granulosus Mitotic checkpoint protein PRCC C terminal 0.0135 0.0364 0.0363
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0022 0.0013 0.0032
Toxoplasma gondii thioredoxin reductase 0.0099 0.0254 0.069
Trypanosoma brucei calpain-like cysteine peptidase, putative 0.028 0.0816 0.1787
Loa Loa (eye worm) ctsf protein 0.1143 0.3508 0.3508
Trypanosoma cruzi unspecified product 0.0381 0.113 0.1129
Loa Loa (eye worm) cathepsin B 0.1195 0.3668 0.3668
Giardia lamblia Hypothetical protein 0.0363 0.1074 0.2926
Echinococcus multilocularis calcium uptake protein 1 0.0176 0.0492 0.0491
Trypanosoma cruzi cruzipain precursor, putative 0.0348 0.1029 0.1028
Trypanosoma cruzi cysteine peptidase (N-terminal), putative 0.0633 0.1918 0.1917
Loa Loa (eye worm) hypothetical protein 0.0018 0.0001 0.0001
Loa Loa (eye worm) calpain D 0.046 0.1379 0.1379
Mycobacterium ulcerans hydrolase 0.0027 0.0027 0.0622
Trypanosoma cruzi caltractin, putative 0.0172 0.0481 0.048
Leishmania major sir2-family protein-like protein 0.0081 0.0197 0.0429
Trypanosoma cruzi centrin, putative 0.02 0.0569 0.0568
Plasmodium vivax glutathione reductase, putative 0.0099 0.0254 0.0686
Schistosoma mansoni chromatin regulatory protein sir2 0.0295 0.0864 0.0864
Trypanosoma cruzi cysteine peptidase, putative 0.1285 0.3951 0.3951
Schistosoma mansoni subfamily C1A non-peptidase homologue (C01 family) 0.0285 0.0833 0.0833
Schistosoma mansoni hypothetical protein 0.0047 0.0089 0.0089
Plasmodium vivax cysteine repeat modular protein 1, putative 0.0023 0.0016 0.004
Toxoplasma gondii histone deacetylase SIR2 0.0081 0.0197 0.0534
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0285 0.0833 0.2268
Mycobacterium leprae PROBABLE NADH DEHYDROGENASE NDH 0.0227 0.0651 0.8878
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0063 0.0141 0.014
Trichomonas vaginalis centrin, putative 0.0172 0.0481 0.131
Brugia malayi Matrixin family protein 0.0053 0.0108 0.0107
Brugia malayi Bloom's syndrome protein homolog 0.0023 0.0015 0.0014
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.0285 0.0833 0.0833
Loa Loa (eye worm) hypothetical protein 0.003 0.0036 0.0036
Plasmodium vivax hypothetical protein, conserved 0.0039 0.0064 0.0171
Echinococcus multilocularis Peptidase S1 S6, chymotrypsin Hap 0.0047 0.0089 0.0088
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0034 0.0051 0.005
Loa Loa (eye worm) MH1 domain-containing protein 0.0024 0.002 0.002
Onchocerca volvulus 0.0028 0.0032 0.0044
Schistosoma mansoni coup transcription factor 0.0021 0.0009 0.0009
Mycobacterium tuberculosis Probable lipase LipE 0.0039 0.0064 0.0865
Loa Loa (eye worm) GTP-binding regulatory protein Gs alpha-S chain 0.0137 0.0372 0.0372
Trypanosoma cruzi dihydrolipoyl dehydrogenase, putative 0.0034 0.0051 0.005
Schistosoma mansoni proteasome subunit beta 1 (T01 family) 0.0066 0.0151 0.015
Toxoplasma gondii calcium binding egf domain-containing protein 0.003 0.0036 0.0096
Trypanosoma cruzi hypothetical protein, conserved 0.0221 0.0632 0.0631
Trichomonas vaginalis calmodulin-2, putative 0.0172 0.0481 0.131
Onchocerca volvulus 0.0031 0.004 0.006
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.1143 0.3508 0.9564
Loa Loa (eye worm) hypothetical protein 0.0028 0.0032 0.0032
Onchocerca volvulus 0.0795 0.2424 0.4751
Plasmodium vivax vivapain-3 0.0633 0.1918 0.5198
Echinococcus multilocularis cathepsin L cysteine protease 0.1143 0.3508 0.3508
Entamoeba histolytica cysteine protease, putative 0.0633 0.1918 0.5464
Loa Loa (eye worm) calpain family protein 1 0.2111 0.6527 0.6527
Loa Loa (eye worm) hypothetical protein 0.0285 0.0833 0.0833
Trichomonas vaginalis chromatin regulatory protein sir2, putative 0.0295 0.0864 0.2354
Echinococcus multilocularis mothers against decapentaplegic 5 0.0024 0.002 0.0019
Giardia lamblia Proteasome subunit beta type 1 0.0066 0.0151 0.0408
Schistosoma mansoni hypothetical protein 0.0172 0.0481 0.0481
Loa Loa (eye worm) pre-SET domain-containing protein family protein 0.0429 0.128 0.128
Trypanosoma cruzi calpain-like cysteine peptidase, putative 0.1402 0.4316 0.4316
Plasmodium falciparum dihydrolipoyl dehydrogenase, apicoplast 0.0034 0.0051 0.0143
Mycobacterium ulcerans lipase LipD 0.0039 0.0064 0.1536
Schistosoma mansoni calmodulin related calcium binding protein 0.0172 0.0481 0.0481
Schistosoma mansoni family C2 unassigned peptidase (C02 family) 0.3024 0.9373 0.9373
Toxoplasma gondii centrin family protein 0.0028 0.0032 0.0083
Giardia lamblia Cathepsin L precursor 0.0285 0.0833 0.2268
Echinococcus multilocularis tachykinin peptides receptor 99D 0.0596 0.1803 0.1802
Loa Loa (eye worm) hypothetical protein 0.0047 0.0089 0.0089
Trypanosoma brucei proteasome beta 6 subunit 0.0066 0.0151 0.0328
Trichomonas vaginalis conserved hypothetical protein 0.002 0.0005 0.0012
Brugia malayi transcriptional regulator, Sir2 family protein 0.0363 0.1074 0.1073
Echinococcus multilocularis Nuclear hormone receptor family member nhr 41 0.0021 0.0009 0.0008
Echinococcus multilocularis EF HAND 1, calcium binding site 0.0172 0.0481 0.048
Brugia malayi beta-lactamase 0.0039 0.0064 0.0063
Leishmania major cathepsin L-like protease 0.1143 0.3508 0.7694
Trichomonas vaginalis conserved hypothetical protein 0.046 0.1379 0.3758
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0021 0.0009 0.0008
Leishmania major calmodulin, putative 0.0172 0.0481 0.1053
Trypanosoma brucei DNA polymerase kappa, putative 0.0021 0.0008 0.0016
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.1143 0.3508 0.9564
Brugia malayi Neuronal calcium sensor family protein 1 0.0028 0.0032 0.003
Schistosoma mansoni Sarcoplasmic calcium-binding protein (SCP). 0.0172 0.0481 0.0481
Plasmodium vivax SET domain protein, putative 0.0063 0.0141 0.0379
Loa Loa (eye worm) MH2 domain-containing protein 0.0357 0.1058 0.1058
Leishmania major calpain family cysteine protease-like protein 0.0681 0.2067 0.4532
Echinococcus granulosus NAD dependent deacetylase sirtuin 1 0.0295 0.0864 0.0863
Trichomonas vaginalis calpain, putative 0.046 0.1379 0.3758
Trypanosoma brucei META domain/Domain of unknown function (DUF1935), putative 0.0221 0.0632 0.1383
Mycobacterium ulcerans Sir2-like regulatory protein 0.0081 0.0197 0.4768
Schistosoma mansoni calcium binding atopy-related autoantigen 0.0176 0.0492 0.0492
Echinococcus granulosus calbindin 32 0.0176 0.0492 0.0491
Echinococcus multilocularis cathepsin l cysteine peptidase 0.1143 0.3508 0.3508
Schistosoma mansoni Tr4/Tr2 (homologue) 0.0021 0.0009 0.0009
Trypanosoma brucei centrin, putative 0.0172 0.0481 0.1053
Mycobacterium tuberculosis Conserved protein 0.0039 0.0064 0.0865
Onchocerca volvulus 0.0172 0.0481 0.0929
Loa Loa (eye worm) EF hand family protein 0.0172 0.0481 0.0481
Trichomonas vaginalis Clan CA, family C2, calpain-like cysteine peptidase 0.046 0.1379 0.3758
Trypanosoma brucei dihydrolipoyl dehydrogenase 0.0034 0.0051 0.011
Echinococcus multilocularis NAD dependent deacetylase sirtuin 7 0.0081 0.0197 0.0196
Toxoplasma gondii histone deacetylase SIR2-like 0.0081 0.0197 0.0534
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.1143 0.3508 0.9564
Plasmodium vivax vivapain-2 0.1143 0.3508 0.9513
Loa Loa (eye worm) hypothetical protein 0.0054 0.0113 0.0113
Brugia malayi alpha keto acid dehydrogenase complex, E3 component, lipoamide dehydrogenase 0.0025 0.0023 0.0022
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.1285 0.3951 0.8666
Trypanosoma cruzi calpain-like cysteine peptidase, putative 0.0221 0.0632 0.0631
Trypanosoma cruzi cysteine peptidase, putative 0.1285 0.3951 0.3951
Loa Loa (eye worm) hypothetical protein 0.0021 0.0009 0.0009
Brugia malayi MH2 domain containing protein 0.0357 0.1058 0.1057
Loa Loa (eye worm) hypothetical protein 0.0037 0.0061 0.0061
Brugia malayi Cathepsin L-like precursor 0.1143 0.3508 0.3508
Loa Loa (eye worm) hypothetical protein 0.0039 0.0064 0.0064
Trichomonas vaginalis bromodomain-containing protein, putative 0.0043 0.0079 0.0212
Mycobacterium tuberculosis Probable soluble pyridine nucleotide transhydrogenase SthA (STH) (NAD(P)(+) transhydrogenase [B-specific]) (nicotinamide nucleot 0.0034 0.0051 0.069
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.148 0.456 1
Trypanosoma brucei protein I/6 0.0172 0.0481 0.1053
Loa Loa (eye worm) transcriptional regulator 0.0081 0.0197 0.0197
Echinococcus multilocularis Calcium binding protein 0.0028 0.0032 0.003
Brugia malayi ImpB/MucB/SamB family protein 0.0048 0.0093 0.0092
Trypanosoma cruzi cysteine peptidase, Clan CA, family C2, putative 0.0834 0.2545 0.2544
Trypanosoma brucei Calpain-like protein 2 0.0815 0.2486 0.5451
Trypanosoma cruzi CAMK/CAMKL family protein kinase, putative 0.0172 0.0481 0.048
Entamoeba histolytica cysteine proteinase 2 0.0633 0.1918 0.5464
Giardia lamblia Cathepsin B-like cysteine proteinase 3 precursor 0.0285 0.0833 0.2268
Onchocerca volvulus Cathepsin F homolog 0.1143 0.3508 0.6885
Schistosoma mansoni nuclear hormone receptor 0.0021 0.0009 0.0009
Loa Loa (eye worm) hypothetical protein 0.0058 0.0125 0.0125
Mycobacterium tuberculosis Conserved protein 0.0039 0.0064 0.0865
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.1143 0.3508 0.9564
Toxoplasma gondii calmodulin, putative 0.0028 0.0032 0.0083
Trypanosoma cruzi DNA polymerase kappa, putative 0.0021 0.0008 0.0007
Loa Loa (eye worm) hypothetical protein 0.0021 0.0009 0.0009
Brugia malayi dihydrolipoyl dehydrogenase, mitochondrial precursor, putative 0.0034 0.0051 0.005
Leishmania major cytochrome p450-like protein 0.0032 0.0044 0.0095
Echinococcus granulosus 5'partial|histone lysine N methyltransferase SETDB2 0.0059 0.0128 0.0127
Echinococcus granulosus transmembrane protease serine 3 0.0047 0.0089 0.0088
Trypanosoma brucei calpain-like protein, putative 0.1201 0.3688 0.8088
Trypanosoma cruzi calpain-like cysteine peptidase, putative 0.028 0.0816 0.0815
Echinococcus granulosus bloom syndrome protein 0.0023 0.0015 0.0014
Trypanosoma cruzi cysteine peptidase, Clan CA, family C2, putative 0.08 0.2438 0.2437
Onchocerca volvulus 0.1143 0.3508 0.6885
Schistosoma mansoni smad 0.0024 0.002 0.002
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0021 0.0009 0.0008
Schistosoma mansoni gcn5proteinral control of amino-acid synthesis 5-like 2 gcnl2 0.0147 0.0403 0.0403
Trypanosoma brucei glucosamine 6-phosphate n-acetyltransferase 0.0461 0.1381 0.3027
Loa Loa (eye worm) calmodulin-like protein 0.0172 0.0481 0.0481
Schistosoma mansoni calmodulin-related 0.0028 0.0032 0.0031
Echinococcus multilocularis thyroid hormone receptor alpha 0.0156 0.043 0.0429
Trypanosoma cruzi hypothetical protein, conserved 0.0221 0.0632 0.0631
Toxoplasma gondii calmodulin CAM2 0.0028 0.0032 0.0083
Toxoplasma gondii calcium-dependent protein kinase 0.0176 0.0492 0.1339
Entamoeba histolytica cysteine protease, putative 0.0633 0.1918 0.5464

Activities

Activity type Activity value Assay description Source Reference
MST (functional) ND 0 day Antimalarial effect measured against trophozoite induced P. berghei in mice at dosage of 640 mg/kg after sc administration ChEMBL. 7009867
MST (functional) ND 0 day Antimalarial effect against trophozoite-induced Plasmodium berghei in mice. ChEMBL. 7009867
MST (functional) = 0.3 day Antimalarial effect of the compound was measured against trophozoite induced Plasmodium berghei in mice after subcutaneous administration at 40 mg/kg ChEMBL. 7009867
MST (functional) = 0.3 day Antimalarial effect of the compound was measured against trophozoite induced Plasmodium berghei in mice at dosage of 20 mg/kg after subcutaneous administration. ChEMBL. 7009867
MST (functional) = 0.3 day Antimalarial effect of the compound was measured against trophozoite induced Plasmodium berghei in mice after subcutaneous administration at 40 mg/kg ChEMBL. 7009867
MST (functional) = 0.3 day Antimalarial effect of the compound was measured against trophozoite induced Plasmodium berghei in mice at dosage of 20 mg/kg after subcutaneous administration. ChEMBL. 7009867
MST (functional) = 0.5 day Antimalarial effect of the compound was measured against trophozoite induced Plasmodium berghei in mice after subcutaneous administration at 40 mg/kg ChEMBL. 7009867
MST (functional) = 0.5 day Antimalarial effect of the compound was measured against trophozoite induced Plasmodium berghei in mice at dosage of 20 mg/kg after subcutaneous administration. ChEMBL. 7009867
MST (functional) = 0.5 day Antimalarial effect of the compound was measured against trophozoite induced Plasmodium berghei in mice after subcutaneous administration at 40 mg/kg ChEMBL. 7009867
MST (functional) = 0.5 day Antimalarial effect of the compound was measured against trophozoite induced Plasmodium berghei in mice at dosage of 20 mg/kg after subcutaneous administration. ChEMBL. 7009867
MST (functional) = 2.5 day Antimalarial effect measured in trophozoite induced P. berghei mice at dose of 80 mg/kg after sc administration. ChEMBL. 7009867
MST (functional) = 2.5 day Antimalarial effect measured in trophozoite induced P. berghei mice at dose of 80 mg/kg after sc administration. ChEMBL. 7009867
MST (functional) = 2.7 day Antimalarial effect measured in trophozoite induced P. berghei mice at dose of 80 mg/kg after sc administration. ChEMBL. 7009867
MST (functional) = 2.7 day Antimalarial effect measured in trophozoite induced P. berghei mice at dose of 80 mg/kg after sc administration. ChEMBL. 7009867
MST (functional) = 10.1 day Antimalarial effect against trophozoite induced Plasmodium berghei in mice at dosage of 160 mg/kg after subcutaneous administration. ChEMBL. 7009867
MST (functional) = 10.1 day Antimalarial effect against trophozoite induced Plasmodium berghei in mice at dosage of 160 mg/kg after subcutaneous administration. ChEMBL. 7009867
MST (functional) = 10.3 day Antimalarial effect against trophozoite induced Plasmodium berghei in mice at dosage of 160 mg/kg after subcutaneous administration. ChEMBL. 7009867
MST (functional) = 10.3 day Antimalarial effect against trophozoite induced Plasmodium berghei in mice at dosage of 160 mg/kg after subcutaneous administration. ChEMBL. 7009867
MST (functional) = 12.7 day Antimalarial effect against trophozoite induced Plasmodium berghei in mice at dosage of 320 mg/kg after sc administration ChEMBL. 7009867
MST (functional) = 12.7 day Antimalarial effect against trophozoite induced Plasmodium berghei in mice at dosage of 320 mg/kg after sc administration ChEMBL. 7009867
MST (functional) = 12.9 day Antimalarial effect against trophozoite induced Plasmodium berghei in mice at dosage of 320 mg/kg after sc administration ChEMBL. 7009867
MST (functional) = 12.9 day Antimalarial effect against trophozoite induced Plasmodium berghei in mice at dosage of 320 mg/kg after sc administration ChEMBL. 7009867
No. of survivals (functional) = 2 Number of mice cured at a dose of 640 mg/kg sc ChEMBL. 7009867
No. of survivals (functional) = 3 Number of mice cured at a dose of 640 mg/kg sc ChEMBL. 7009867
No. of survivals (functional) = 2 Number of mice cured at a dose of 640 mg/kg sc ChEMBL. 7009867
No. of survivals (functional) = 3 Number of mice cured at a dose of 640 mg/kg sc ChEMBL. 7009867
Ratio (functional) ND 0 The ratio of SD90 of the quinine hydrocloride, to the SD90 of the test substance for the Dose of mg/kg ChEMBL. 7009867

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
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External resources for this compound

Bibliographic References

1 literature reference was collected for this gene.

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