Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Onchocerca volvulus | 0.0019 | 0.0493 | 0.0746 | |
Echinococcus granulosus | Aryl hydrocarbon receptor nuclear | 0.0015 | 0.0274 | 0.0268 |
Loa Loa (eye worm) | jmjC domain-containing protein | 0.0018 | 0.047 | 0.0463 |
Brugia malayi | oxidoreductase, short chain dehydrogenase/reductase family protein | 0.0013 | 0.0185 | 0.0185 |
Loa Loa (eye worm) | papain family cysteine protease containing protein | 0.0019 | 0.0493 | 0.0487 |
Mycobacterium tuberculosis | Probable soluble pyridine nucleotide transhydrogenase SthA (STH) (NAD(P)(+) transhydrogenase [B-specific]) (nicotinamide nucleot | 0.0018 | 0.0471 | 0.0412 |
Entamoeba histolytica | oxidoreductase, short chain dehydrogenase/reductase family | 0.0013 | 0.0185 | 0.0212 |
Schistosoma mansoni | cathepsin F (C01 family) | 0.0019 | 0.0493 | 0.035 |
Mycobacterium ulcerans | short-chain type dehydrogenase/reductase | 0.0072 | 0.3497 | 0.4763 |
Plasmodium falciparum | AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative | 0.0022 | 0.0672 | 0.2216 |
Onchocerca volvulus | 0.0019 | 0.0493 | 0.0746 | |
Onchocerca volvulus | 0.0013 | 0.0185 | 0.0074 | |
Echinococcus multilocularis | caspase 2 | 0.0095 | 0.4746 | 0.4767 |
Brugia malayi | oxidoreductase, short chain dehydrogenase/reductase family protein | 0.0013 | 0.0185 | 0.0185 |
Echinococcus granulosus | caspase 8 | 0.0049 | 0.2195 | 0.2202 |
Mycobacterium tuberculosis | Probable aldehyde dehydrogenase | 0.0137 | 0.7138 | 1 |
Loa Loa (eye worm) | thioredoxin reductase | 0.0052 | 0.2384 | 0.2379 |
Brugia malayi | dehydrogenases, short chain protein 2 | 0.0013 | 0.0185 | 0.0185 |
Trypanosoma cruzi | cruzipain precursor, putative | 0.0071 | 0.3406 | 1 |
Trypanosoma brucei | metacaspase MCA2 | 0.0049 | 0.2195 | 0.6242 |
Echinococcus granulosus | 3 ketodihydrosphingosine reductase | 0.0013 | 0.0185 | 0.0179 |
Schistosoma mansoni | aryl hydrocarbon receptor | 0.0056 | 0.26 | 0.25 |
Echinococcus multilocularis | cathepsin l cysteine peptidase | 0.0019 | 0.0493 | 0.0489 |
Echinococcus granulosus | guanine nucleotide binding protein Gs subunit | 0.0053 | 0.2412 | 0.242 |
Loa Loa (eye worm) | hypothetical protein | 0.0065 | 0.3105 | 0.31 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0019 | 0.0493 | 0.1676 |
Echinococcus granulosus | phd:f box containing protein | 0.0018 | 0.047 | 0.0466 |
Trypanosoma cruzi | metacaspase, putative | 0.0049 | 0.2195 | 0.6242 |
Mycobacterium ulcerans | aldehyde dehydrogenase | 0.0137 | 0.7138 | 1 |
Echinococcus multilocularis | steroid dehydrogenase | 0.0013 | 0.0185 | 0.0179 |
Trypanosoma cruzi | STE group serine/threonine-protein kinase, putative | 0.0015 | 0.0274 | 0.0277 |
Echinococcus multilocularis | lysine specific demethylase 6a | 0.0018 | 0.047 | 0.0466 |
Echinococcus multilocularis | JmjC domain containing protein 4 | 0.0018 | 0.047 | 0.0466 |
Entamoeba histolytica | estradiol 17-beta-dehydrogenase, putative | 0.0013 | 0.0185 | 0.0212 |
Brugia malayi | D-beta-hydroxybutyrate dehydrogenase, mitochondrial precursor | 0.0013 | 0.0185 | 0.0185 |
Brugia malayi | oxidoreductase, short chain dehydrogenase/reductase family protein | 0.0013 | 0.0185 | 0.0185 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.0019 | 0.0493 | 0.1676 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0071 | 0.3406 | 1 |
Echinococcus multilocularis | tar DNA binding protein | 0.007 | 0.3378 | 0.3392 |
Onchocerca volvulus | 0.0019 | 0.0493 | 0.0746 | |
Trypanosoma cruzi | dihydrolipoamide dehydrogenase, putative | 0.0018 | 0.0471 | 0.089 |
Trypanosoma brucei | dihydrolipoamide dehydrogenase | 0.0018 | 0.0471 | 0.089 |
Echinococcus multilocularis | guanine nucleotide binding protein G(s) subunit | 0.0053 | 0.2412 | 0.242 |
Echinococcus multilocularis | carbonyl reductase 1 | 0.0013 | 0.0185 | 0.0179 |
Onchocerca volvulus | 0.0013 | 0.0185 | 0.0074 | |
Echinococcus multilocularis | oxidoreductase | 0.0013 | 0.0185 | 0.0179 |
Brugia malayi | Thioredoxin reductase | 0.0052 | 0.2384 | 0.2384 |
Onchocerca volvulus | Dehydrogenase\/reductase SDR family member 13 homolog | 0.0013 | 0.0185 | 0.0074 |
Brugia malayi | jmjC domain containing protein | 0.0018 | 0.047 | 0.047 |
Entamoeba histolytica | hypothetical protein, conserved | 0.0013 | 0.0185 | 0.0212 |
Mycobacterium tuberculosis | Probable NADH dehydrogenase Ndh | 0.0119 | 0.6134 | 0.8556 |
Plasmodium vivax | hypothetical protein, conserved | 0.0049 | 0.2195 | 0.9142 |
Brugia malayi | Dehydrogenases, short chain protein 30 | 0.0013 | 0.0185 | 0.0185 |
Wolbachia endosymbiont of Brugia malayi | fructose-1,6-bisphosphatase | 0.0041 | 0.1743 | 1 |
Echinococcus multilocularis | thioredoxin glutathione reductase | 0.0052 | 0.2384 | 0.2392 |
Trichomonas vaginalis | adenylate and guanylate cyclases, putative | 0.0015 | 0.0274 | 0.0601 |
Trypanosoma cruzi | metacaspase, putative | 0.0049 | 0.2195 | 0.6242 |
Plasmodium falciparum | dihydrolipoyl dehydrogenase, mitochondrial | 0.0018 | 0.0471 | 0.1303 |
Schistosoma mansoni | protein phosphatase 2C | 0.0018 | 0.047 | 0.0326 |
Trypanosoma cruzi | JmjC domain, hydroxylase, putative | 0.0018 | 0.047 | 0.0886 |
Schistosoma mansoni | steroid dehydrogenase | 0.0013 | 0.0185 | 0.0035 |
Schistosoma mansoni | short chain dehydrogenase | 0.0013 | 0.0185 | 0.0035 |
Trypanosoma cruzi | trypanothione reductase, putative | 0.0018 | 0.0471 | 0.089 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0019 | 0.0493 | 0.1676 |
Echinococcus granulosus | WW domain containing oxidoreductase | 0.0013 | 0.0185 | 0.0179 |
Trypanosoma brucei | metacaspase MCA3 | 0.0049 | 0.2195 | 0.6242 |
Onchocerca volvulus | 0.0013 | 0.0185 | 0.0074 | |
Brugia malayi | Cathepsin L-like precursor | 0.0012 | 0.0151 | 0.0151 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.0019 | 0.0493 | 0.1676 |
Trypanosoma cruzi | STE/STE11 serine/threonine-protein kinase, putative | 0.0015 | 0.0274 | 0.0277 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0019 | 0.0493 | 0.1676 |
Loa Loa (eye worm) | hypothetical protein | 0.0015 | 0.0274 | 0.0267 |
Plasmodium falciparum | cysteine proteinase falcipain 2a | 0.0019 | 0.0493 | 0.1404 |
Brugia malayi | oxidoreductase, short chain dehydrogenase/reductase family protein | 0.0013 | 0.0185 | 0.0185 |
Schistosoma mansoni | tar DNA-binding protein | 0.007 | 0.3378 | 0.3295 |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.0053 | 0.2412 | 0.2308 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0049 | 0.2195 | 1 |
Echinococcus multilocularis | estradiol 17 beta dehydrogenase 12 | 0.0013 | 0.0185 | 0.0179 |
Brugia malayi | oxidoreductase, short chain dehydrogenase/reductase family protein | 0.0013 | 0.0185 | 0.0185 |
Schistosoma mansoni | short chain dehydrogenase | 0.0013 | 0.0185 | 0.0035 |
Trichomonas vaginalis | adenylate and guanylate cyclases, putative | 0.0015 | 0.0274 | 0.0601 |
Trichomonas vaginalis | estradiol 17 beta-dehydrogenase, putative | 0.0013 | 0.0185 | 0.0165 |
Schistosoma mansoni | phd/f-box containing protein | 0.0018 | 0.047 | 0.0326 |
Schistosoma mansoni | carbonyl reductase | 0.0013 | 0.0185 | 0.0035 |
Trichomonas vaginalis | ap endonuclease, putative | 0.0022 | 0.0672 | 0.2549 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0071 | 0.3406 | 1 |
Leishmania major | PAS-domain containing phosphoglycerate kinase, putative | 0.0015 | 0.0274 | 0.0128 |
Leishmania major | protein kinase, putative | 0.0015 | 0.0274 | 0.0128 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0049 | 0.2195 | 1 |
Trypanosoma brucei | Metacaspase-4 | 0.0049 | 0.2195 | 0.6242 |
Schistosoma mansoni | short chain dehydrogenase | 0.0013 | 0.0185 | 0.0035 |
Brugia malayi | CXXC zinc finger family protein | 0.0032 | 0.1235 | 0.1235 |
Echinococcus multilocularis | steroid dehydrogenase | 0.0013 | 0.0185 | 0.0179 |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.0053 | 0.2412 | 0.2308 |
Loa Loa (eye worm) | hypothetical protein | 0.0013 | 0.0185 | 0.0178 |
Onchocerca volvulus | 0.0019 | 0.0493 | 0.0746 | |
Loa Loa (eye worm) | hypothetical protein | 0.0018 | 0.047 | 0.0463 |
Echinococcus granulosus | JmjC domain containing protein 4 | 0.0018 | 0.047 | 0.0466 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0015 | 0.0274 | 0.0601 |
Echinococcus granulosus | thioredoxin glutathione reductase | 0.0052 | 0.2384 | 0.2392 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0071 | 0.3406 | 1 |
Mycobacterium ulcerans | aldehyde dehydrogenase | 0.0137 | 0.7138 | 1 |
Echinococcus multilocularis | epidermal retinal dehydrogenase 2 | 0.0013 | 0.0185 | 0.0179 |
Onchocerca volvulus | 0.0013 | 0.0185 | 0.0074 | |
Echinococcus multilocularis | aldehyde dehydrogenase, mitochondrial | 0.0137 | 0.7138 | 0.7175 |
Schistosoma mansoni | cathepsin F (C01 family) | 0.0019 | 0.0493 | 0.035 |
Loa Loa (eye worm) | short chain dehydrogenase/reductase family oxidoreductase | 0.0013 | 0.0185 | 0.0178 |
Echinococcus granulosus | aldehyde dehydrogenase mitochondrial | 0.0137 | 0.7138 | 0.7175 |
Echinococcus multilocularis | Aryl hydrocarbon receptor nuclear | 0.0015 | 0.0274 | 0.0268 |
Schistosoma mansoni | hypothetical protein | 0.0188 | 0.9946 | 1 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0071 | 0.3406 | 1 |
Schistosoma mansoni | oxidoreductase short chain dehydrogenase/reductase family | 0.0013 | 0.0185 | 0.0035 |
Plasmodium vivax | thioredoxin reductase, putative | 0.0052 | 0.2384 | 1 |
Echinococcus multilocularis | caspase 3 | 0.008 | 0.3959 | 0.3976 |
Onchocerca volvulus | 0.0013 | 0.0185 | 0.0074 | |
Brugia malayi | oxidoreductase, short chain dehydrogenase/reductase family protein | 0.0013 | 0.0185 | 0.0185 |
Brugia malayi | oxidoreductase, short chain dehydrogenase/reductase family protein | 0.0013 | 0.0185 | 0.0185 |
Schistosoma mansoni | tar DNA-binding protein | 0.007 | 0.3378 | 0.3295 |
Echinococcus granulosus | caspase 3 | 0.008 | 0.3959 | 0.3976 |
Trichomonas vaginalis | short-chain dehydrogenase, putative | 0.0013 | 0.0185 | 0.0165 |
Trichomonas vaginalis | ap endonuclease, putative | 0.0022 | 0.0672 | 0.2549 |
Trypanosoma cruzi | apurinic/apyrimidinic endonuclease, putative | 0.0022 | 0.0672 | 0.1513 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L or K-like cysteine peptidase | 0.0019 | 0.0493 | 0.1676 |
Mycobacterium ulcerans | aldehyde dehydrogenase | 0.0137 | 0.7138 | 1 |
Schistosoma mansoni | phosphatidylserine receptor | 0.0018 | 0.047 | 0.0326 |
Brugia malayi | jmjC domain containing protein | 0.0018 | 0.047 | 0.047 |
Schistosoma mansoni | short chain dehydrogenase | 0.0013 | 0.0185 | 0.0035 |
Mycobacterium tuberculosis | Putative ferredoxin reductase | 0.0119 | 0.6134 | 0.8556 |
Leishmania major | cathepsin L-like protease | 0.0019 | 0.0493 | 0.0444 |
Echinococcus multilocularis | 3 hydroxyacyl coenzyme A dehydrogenase type 2 | 0.0072 | 0.3497 | 0.3511 |
Schistosoma mansoni | jumonji/arid domain-containing protein | 0.007 | 0.3358 | 0.3274 |
Loa Loa (eye worm) | dehydrogenase | 0.0013 | 0.0185 | 0.0178 |
Echinococcus granulosus | tar DNA binding protein | 0.007 | 0.3378 | 0.3392 |
Loa Loa (eye worm) | jmjC domain-containing protein | 0.0018 | 0.047 | 0.0463 |
Mycobacterium leprae | possible inositol monophosphatase SubH (IMPase) (inositol-1-phosphatase) (I-1-Pase ). | 0.0037 | 0.1504 | 0.1971 |
Onchocerca volvulus | Cathepsin F homolog | 0.0019 | 0.0493 | 0.0746 |
Brugia malayi | Papain family cysteine protease containing protein | 0.0019 | 0.0493 | 0.0493 |
Echinococcus granulosus | retinol dehydrogenase 11 | 0.0013 | 0.0185 | 0.0179 |
Treponema pallidum | exodeoxyribonuclease (exoA) | 0.0022 | 0.0672 | 1 |
Echinococcus granulosus | cpg binding protein | 0.0034 | 0.1336 | 0.1337 |
Plasmodium falciparum | cysteine proteinase falcipain 2b | 0.0019 | 0.0493 | 0.1404 |
Trypanosoma cruzi | cysteine peptidase, clan CA, family C1, cathepsin L-like, putative | 0.0064 | 0.3063 | 0.8936 |
Plasmodium falciparum | thioredoxin reductase | 0.0018 | 0.0471 | 0.1303 |
Brugia malayi | Cathepsin L-like precursor | 0.0019 | 0.0493 | 0.0493 |
Brugia malayi | Cathepsin L-like precursor | 0.0019 | 0.0493 | 0.0493 |
Schistosoma mansoni | cpg binding protein | 0.0032 | 0.1235 | 0.1107 |
Brugia malayi | hypothetical protein | 0.0046 | 0.2007 | 0.2007 |
Mycobacterium tuberculosis | Probable exodeoxyribonuclease III protein XthA (exonuclease III) (EXO III) (AP endonuclease VI) | 0.0022 | 0.0672 | 0.0701 |
Brugia malayi | hypothetical protein | 0.0013 | 0.0185 | 0.0185 |
Trichomonas vaginalis | short-chain dehydrogenase, putative | 0.0013 | 0.0185 | 0.0165 |
Schistosoma mansoni | short-chain dehydrogenase/reductase | 0.0013 | 0.0185 | 0.0035 |
Onchocerca volvulus | 0.0013 | 0.0185 | 0.0074 | |
Schistosoma mansoni | retinal dehydrogenase | 0.0013 | 0.0185 | 0.0035 |
Schistosoma mansoni | short chain dehydrogenase | 0.0013 | 0.0185 | 0.0035 |
Brugia malayi | oxidoreductase, short chain dehydrogenase/reductase family protein | 0.0013 | 0.0185 | 0.0185 |
Schistosoma mansoni | steroid dehydrogenase | 0.0013 | 0.0185 | 0.0035 |
Loa Loa (eye worm) | hypothetical protein | 0.0013 | 0.0185 | 0.0178 |
Entamoeba histolytica | hypothetical protein, conserved | 0.0013 | 0.0185 | 0.0212 |
Echinococcus granulosus | carbonyl reductase 1 | 0.0013 | 0.0185 | 0.0179 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0015 | 0.0274 | 0.0601 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.0019 | 0.0493 | 0.1676 |
Entamoeba histolytica | hypothetical protein | 0.0013 | 0.0185 | 0.0212 |
Echinococcus multilocularis | carbonyl reductase 1 | 0.0013 | 0.0185 | 0.0179 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0071 | 0.3406 | 1 |
Leishmania major | protein kinase, putative | 0.0015 | 0.0274 | 0.0128 |
Echinococcus granulosus | carbonyl reductase 1 | 0.0013 | 0.0185 | 0.0179 |
Schistosoma mansoni | steroid dehydrogenase | 0.0013 | 0.0185 | 0.0035 |
Echinococcus granulosus | 3 hydroxyacyl coenzyme A dehydrogenase type 2 | 0.0072 | 0.3497 | 0.3511 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.0019 | 0.0493 | 0.1676 |
Brugia malayi | Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain containing protein | 0.0013 | 0.0202 | 0.0202 |
Schistosoma mansoni | caspase-7 (C14 family) | 0.0095 | 0.4746 | 0.4691 |
Loa Loa (eye worm) | hypothetical protein | 0.0012 | 0.0151 | 0.0144 |
Schistosoma mansoni | short chain dehydrogenase | 0.0013 | 0.0185 | 0.0035 |
Echinococcus granulosus | jumonji domain containing 1A | 0.0018 | 0.047 | 0.0466 |
Brugia malayi | Cathepsin L-like precursor | 0.0019 | 0.0493 | 0.0493 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0019 | 0.0493 | 0.1676 |
Schistosoma mansoni | ubiquitously transcribed sex (X/Y) chromosome tetratricopeptide repeat protein-related | 0.0018 | 0.047 | 0.0326 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0049 | 0.2195 | 1 |
Echinococcus granulosus | caspase | 0.0129 | 0.6697 | 0.6731 |
Echinococcus multilocularis | retinol dehydrogenase 11 | 0.0013 | 0.0185 | 0.0179 |
Echinococcus multilocularis | carbonyl reductase 1 | 0.0013 | 0.0185 | 0.0179 |
Echinococcus granulosus | Dehydrogenase:reductase SDR family | 0.0013 | 0.0185 | 0.0179 |
Schistosoma mansoni | single-minded | 0.0056 | 0.26 | 0.25 |
Leishmania major | acetoin dehydrogenase e3 component-like protein | 0.0018 | 0.0471 | 0.0412 |
Brugia malayi | jmjC domain containing protein | 0.0018 | 0.047 | 0.047 |
Toxoplasma gondii | histone lysine demethylase JMJD6a | 0.0018 | 0.047 | 0.0411 |
Loa Loa (eye worm) | hypothetical protein | 0.0019 | 0.0493 | 0.0487 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0019 | 0.0493 | 0.1676 |
Mycobacterium ulcerans | putative regulatory protein | 0.0042 | 0.1783 | 0.2298 |
Entamoeba histolytica | short chain dehydrogenase family protein | 0.0013 | 0.0185 | 0.0212 |
Trypanosoma cruzi | PAS-domain containing phosphoglycerate kinase, putative | 0.0015 | 0.0274 | 0.0277 |
Brugia malayi | GTP-binding regulatory protein Gs alpha-S chain, putative | 0.0053 | 0.2412 | 0.2412 |
Trichomonas vaginalis | guanylate cyclase, putative | 0.0015 | 0.0274 | 0.0601 |
Mycobacterium tuberculosis | Probable short-chain type dehydrogenase/reductase | 0.0072 | 0.3497 | 0.4763 |
Trichomonas vaginalis | short-chain dehydrogenase, putative | 0.0013 | 0.0185 | 0.0165 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0019 | 0.0493 | 0.1676 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0019 | 0.0493 | 0.1676 |
Mycobacterium leprae | PROBABLE NADH DEHYDROGENASE NDH | 0.0119 | 0.6134 | 0.8887 |
Chlamydia trachomatis | dihydrolipoyl dehydrogenase | 0.0018 | 0.0471 | 1 |
Echinococcus granulosus | epidermal retinal dehydrogenase 2 | 0.0013 | 0.0185 | 0.0179 |
Plasmodium falciparum | dihydrolipoyl dehydrogenase, apicoplast | 0.0018 | 0.0471 | 0.1303 |
Trichomonas vaginalis | guanylate cyclase, putative | 0.0015 | 0.0274 | 0.0601 |
Trypanosoma cruzi | cysteine peptidase, putative | 0.0071 | 0.3406 | 1 |
Schistosoma mansoni | jumonji domain containing protein | 0.0018 | 0.047 | 0.0326 |
Echinococcus multilocularis | Dehydrogenase:reductase SDR family | 0.0013 | 0.0185 | 0.0179 |
Brugia malayi | Fibroblast growth factor family protein | 0.0065 | 0.3105 | 0.3105 |
Trypanosoma cruzi | dihydrolipoamide dehydrogenase, putative | 0.0018 | 0.0471 | 0.089 |
Loa Loa (eye worm) | oxidoreductase | 0.0013 | 0.0185 | 0.0178 |
Leishmania major | cathepsin L-like protease | 0.0019 | 0.0493 | 0.0444 |
Trichomonas vaginalis | inositol monophosphatase, putative | 0.0041 | 0.1743 | 0.779 |
Mycobacterium tuberculosis | NADPH-dependent mycothiol reductase Mtr | 0.0052 | 0.2384 | 0.3163 |
Loa Loa (eye worm) | hypothetical protein | 0.0013 | 0.0185 | 0.0178 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0071 | 0.3406 | 1 |
Trichomonas vaginalis | adenylate and guanylate cyclases, putative | 0.0015 | 0.0274 | 0.0601 |
Loa Loa (eye worm) | hypothetical protein | 0.0018 | 0.047 | 0.0463 |
Brugia malayi | RNA binding protein | 0.007 | 0.3378 | 0.3378 |
Loa Loa (eye worm) | cysteine protease | 0.0019 | 0.0493 | 0.0487 |
Echinococcus granulosus | steroid dehydrogenase | 0.0013 | 0.0185 | 0.0179 |
Trypanosoma cruzi | apurinic/apyrimidinic endonuclease | 0.0022 | 0.0672 | 0.1513 |
Echinococcus granulosus | cathepsin l cysteine peptidase | 0.0019 | 0.0493 | 0.0489 |
Brugia malayi | glutathione reductase | 0.0052 | 0.2384 | 0.2384 |
Mycobacterium tuberculosis | Inositol-1-monophosphatase SuhB | 0.0037 | 0.1504 | 0.1897 |
Loa Loa (eye worm) | hypoxia-induced factor 1 | 0.0174 | 0.9183 | 0.9183 |
Loa Loa (eye worm) | hypothetical protein | 0.0188 | 1 | 1 |
Echinococcus granulosus | lysine specific demethylase 6a | 0.0018 | 0.047 | 0.0466 |
Plasmodium vivax | dihydrolipoyl dehydrogenase, mitochondrial, putative | 0.0018 | 0.0471 | 0.1303 |
Trichomonas vaginalis | short-chain dehydrogenase, putative | 0.0013 | 0.0185 | 0.0165 |
Loa Loa (eye worm) | CXXC zinc finger family protein | 0.0032 | 0.1235 | 0.1229 |
Brugia malayi | Cathepsin L-like precursor | 0.0019 | 0.0493 | 0.0493 |
Loa Loa (eye worm) | oxidoreductase | 0.0013 | 0.0185 | 0.0178 |
Mycobacterium ulcerans | flavoprotein disulfide reductase | 0.0018 | 0.0471 | 0.0412 |
Trypanosoma brucei | apurinic/apyrimidinic endonuclease, putative | 0.0022 | 0.0672 | 0.1513 |
Loa Loa (eye worm) | hypothetical protein | 0.0018 | 0.047 | 0.0463 |
Trypanosoma cruzi | JmjC domain, hydroxylase, putative | 0.0018 | 0.047 | 0.0886 |
Loa Loa (eye worm) | hypothetical protein | 0.0049 | 0.2195 | 0.219 |
Loa Loa (eye worm) | GTP-binding regulatory protein Gs alpha-S chain | 0.0053 | 0.2412 | 0.2407 |
Trypanosoma cruzi | cysteine peptidase, putative | 0.0071 | 0.3406 | 1 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0019 | 0.0493 | 0.1676 |
Plasmodium vivax | glutathione reductase, putative | 0.0052 | 0.2384 | 1 |
Trypanosoma cruzi | trypanothione reductase, putative | 0.0052 | 0.2384 | 0.6827 |
Trypanosoma brucei | dihydrolipoamide dehydrogenase | 0.0018 | 0.0471 | 0.089 |
Schistosoma mansoni | steroid dehydrogenase | 0.0013 | 0.0185 | 0.0035 |
Mycobacterium leprae | Possible regulatory protein | 0.0015 | 0.0274 | 0.0133 |
Echinococcus multilocularis | cpg binding protein | 0.0034 | 0.1336 | 0.1337 |
Schistosoma mansoni | steroid dehydrogenase | 0.0013 | 0.0185 | 0.0035 |
Schistosoma mansoni | short chain dehydrogenase | 0.0013 | 0.0185 | 0.0035 |
Leishmania major | cathepsin L-like protease | 0.0019 | 0.0493 | 0.0444 |
Toxoplasma gondii | ICE family protease (caspase) p20 domain-containing protein | 0.0049 | 0.2195 | 0.2892 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0015 | 0.0274 | 0.0601 |
Leishmania major | trypanothione reductase | 0.0052 | 0.2384 | 0.3163 |
Brugia malayi | Cathepsin L-like precursor | 0.0012 | 0.0151 | 0.0151 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0049 | 0.2195 | 1 |
Leishmania major | cathepsin L-like protease | 0.0071 | 0.3406 | 0.4633 |
Mycobacterium tuberculosis | Probable nitrite reductase [NAD(P)H] large subunit [FAD flavoprotein] NirB | 0.0119 | 0.6134 | 0.8556 |
Onchocerca volvulus | 0.0013 | 0.0185 | 0.0074 | |
Entamoeba histolytica | cysteine protease, putative | 0.0019 | 0.0493 | 0.2152 |
Onchocerca volvulus | 0.0013 | 0.0185 | 0.0074 | |
Loa Loa (eye worm) | ctsf protein | 0.0019 | 0.0493 | 0.0487 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.0019 | 0.0493 | 0.1676 |
Trypanosoma brucei | JmjC domain, hydroxylase, putative | 0.0018 | 0.047 | 0.0886 |
Trichomonas vaginalis | mercuric reductase, putative | 0.0018 | 0.0471 | 0.1567 |
Loa Loa (eye worm) | hypothetical protein | 0.0013 | 0.0185 | 0.0178 |
Brugia malayi | oxidoreductase, short chain dehydrogenase/reductase family protein | 0.0013 | 0.0185 | 0.0185 |
Trichomonas vaginalis | Clan CD, family C14, metacaspase-like cysteine peptidase | 0.0049 | 0.2195 | 1 |
Entamoeba histolytica | estradiol 17-beta-dehydrogenase, putative | 0.0013 | 0.0185 | 0.0212 |
Trichomonas vaginalis | short-chain dehydrogenases/reductase, putative | 0.0013 | 0.0185 | 0.0165 |
Echinococcus granulosus | Jumonji AT rich interactive domain 1B | 0.002 | 0.0572 | 0.0568 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0019 | 0.0493 | 0.1676 |
Brugia malayi | oxidoreductase, short chain dehydrogenase/reductase family protein | 0.0013 | 0.0185 | 0.0185 |
Trichomonas vaginalis | steroid dehydrogenase, putative | 0.0013 | 0.0185 | 0.0165 |
Trichomonas vaginalis | myo inositol monophosphatase, putative | 0.0041 | 0.1743 | 0.779 |
Schistosoma mansoni | 3-hydroxyacyl-CoA dehydrogenase | 0.0072 | 0.3497 | 0.3416 |
Schistosoma mansoni | tar DNA-binding protein | 0.007 | 0.3378 | 0.3295 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0071 | 0.3406 | 1 |
Brugia malayi | oxidoreductase, short chain dehydrogenase/reductase family protein | 0.0013 | 0.0185 | 0.0185 |
Leishmania major | myo-inositol-1(or 4)-monophosphatase 1, putative | 0.0041 | 0.1743 | 0.2242 |
Leishmania major | dihydrolipoamide dehydrogenase, putative | 0.0018 | 0.0471 | 0.0412 |
Echinococcus granulosus | apoptotic protease activating factor 1 | 0.0046 | 0.2007 | 0.2012 |
Echinococcus multilocularis | 3 ketodihydrosphingosine reductase | 0.0013 | 0.0185 | 0.0179 |
Echinococcus multilocularis | caspase | 0.0129 | 0.6697 | 0.6731 |
Onchocerca volvulus | 0.0046 | 0.2007 | 0.404 | |
Echinococcus multilocularis | guanine nucleotide binding protein G(s) subunit | 0.0053 | 0.2412 | 0.242 |
Trichomonas vaginalis | Clan CD, family C14, metacaspase-like cysteine peptidase | 0.0049 | 0.2195 | 1 |
Trichomonas vaginalis | short-chain dehydrogenase, putative | 0.0013 | 0.0185 | 0.0165 |
Schistosoma mansoni | subfamily C14A unassigned peptidase (C14 family) | 0.0049 | 0.2195 | 0.2087 |
Brugia malayi | Retinol dehydrogenase 12 | 0.0013 | 0.0185 | 0.0185 |
Brugia malayi | jmjC domain containing protein | 0.0068 | 0.3256 | 0.3256 |
Schistosoma mansoni | short chain dehydrogenase | 0.0013 | 0.0185 | 0.0035 |
Giardia lamblia | Endonuclease/Exonuclease/phosphatase | 0.0022 | 0.0672 | 0.1669 |
Trichomonas vaginalis | Clan CD, family C14, metacaspase-like cysteine peptidase | 0.0049 | 0.2195 | 1 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0019 | 0.0493 | 0.1676 |
Trypanosoma cruzi | cysteine peptidase, putative | 0.0019 | 0.0493 | 0.0959 |
Brugia malayi | hypothetical protein | 0.0013 | 0.0185 | 0.0185 |
Brugia malayi | Inositol-1 | 0.0041 | 0.1743 | 0.1743 |
Wolbachia endosymbiont of Brugia malayi | dihydrolipoamide dehydrogenase E3 component | 0.0018 | 0.0471 | 0.1839 |
Echinococcus multilocularis | apoptotic protease activating factor 1 | 0.0046 | 0.2007 | 0.2012 |
Onchocerca volvulus | Cathepsin L homolog | 0.0019 | 0.0493 | 0.0746 |
Loa Loa (eye worm) | hypothetical protein | 0.0013 | 0.0185 | 0.0178 |
Schistosoma mansoni | short chain dehydrogenase | 0.0013 | 0.0185 | 0.0035 |
Toxoplasma gondii | histone lysine methyltransferase SET1 | 0.006 | 0.2825 | 0.3797 |
Onchocerca volvulus | 0.0019 | 0.0493 | 0.0746 | |
Echinococcus multilocularis | dihydrolipoamide dehydrogenase | 0.0018 | 0.0471 | 0.0467 |
Echinococcus multilocularis | Transcription factor, JmjC domain containing protein | 0.0068 | 0.3256 | 0.3269 |
Schistosoma mansoni | short chain dehydrogenase | 0.0013 | 0.0185 | 0.0035 |
Plasmodium vivax | vivapain-2 | 0.0019 | 0.0493 | 0.1404 |
Plasmodium falciparum | cysteine proteinase falcipain 3 | 0.0019 | 0.0493 | 0.1404 |
Mycobacterium tuberculosis | NAD(P)H quinone reductase LpdA | 0.0133 | 0.6879 | 0.9627 |
Echinococcus granulosus | cathepsin L cysteine proteinase | 0.0019 | 0.0493 | 0.0489 |
Onchocerca volvulus | 0.0013 | 0.0185 | 0.0074 | |
Echinococcus multilocularis | transient receptor potential cation channel | 0.0013 | 0.0185 | 0.0179 |
Loa Loa (eye worm) | jmjC domain-containing protein | 0.007 | 0.3358 | 0.3353 |
Trypanosoma brucei | dihydrolipoamide dehydrogenase, point mutation | 0.0018 | 0.0471 | 0.089 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.0019 | 0.0493 | 0.1676 |
Onchocerca volvulus | 0.0042 | 0.1783 | 0.3552 | |
Loa Loa (eye worm) | RNA binding protein | 0.007 | 0.3378 | 0.3374 |
Brugia malayi | TAR-binding protein | 0.007 | 0.3378 | 0.3378 |
Onchocerca volvulus | 0.0019 | 0.0493 | 0.0746 | |
Loa Loa (eye worm) | 3-hydroxyacyl-CoA dehydrogenase type II | 0.0059 | 0.2769 | 0.2764 |
Trypanosoma cruzi | STE/STE11 serine/threonine-protein kinase, putative | 0.0015 | 0.0274 | 0.0277 |
Mycobacterium ulcerans | short-chain type dehydrogenase/reductase | 0.0072 | 0.3497 | 0.4763 |
Schistosoma mansoni | short chain dehydrogenase | 0.0013 | 0.0185 | 0.0035 |
Schistosoma mansoni | steroid dehydrogenase | 0.0013 | 0.0185 | 0.0035 |
Mycobacterium ulcerans | dihydrolipoamide dehydrogenase, LpdB | 0.0018 | 0.0471 | 0.0412 |
Toxoplasma gondii | pyruvate dehydrogenase complex subunit PDH-E3II | 0.0018 | 0.0471 | 0.0412 |
Loa Loa (eye worm) | hypothetical protein | 0.0046 | 0.2007 | 0.2002 |
Echinococcus multilocularis | inositol monophosphatase 1 | 0.0041 | 0.1743 | 0.1747 |
Echinococcus granulosus | cathepsin l1 | 0.0012 | 0.0151 | 0.0145 |
Mycobacterium ulcerans | extragenic suppressor protein SuhB | 0.0041 | 0.1743 | 0.2242 |
Echinococcus granulosus | geminin | 0.0188 | 0.9946 | 1 |
Loa Loa (eye worm) | oxidoreductase | 0.0013 | 0.0185 | 0.0178 |
Leishmania major | 3-oxoacyl-(acyl-carrier protein) reductase, putative | 0.0072 | 0.3497 | 0.4763 |
Echinococcus granulosus | DNA apurinic or apyrimidinic site lyase | 0.0022 | 0.0672 | 0.0669 |
Echinococcus multilocularis | cathepsin l cysteine peptidase | 0.0019 | 0.0493 | 0.0489 |
Plasmodium vivax | dihydrolipoyl dehydrogenase, apicoplast, putative | 0.0018 | 0.0471 | 0.1303 |
Trichomonas vaginalis | glutathione reductase, putative | 0.0018 | 0.0471 | 0.1567 |
Brugia malayi | cathepsin L-like precursor | 0.0012 | 0.0151 | 0.0151 |
Entamoeba histolytica | 3-ketodihydrosphingosine reductase protein, putative | 0.0013 | 0.0185 | 0.0212 |
Brugia malayi | oxidoreductase, short chain dehydrogenase/reductase family protein | 0.0013 | 0.0185 | 0.0185 |
Schistosoma mansoni | steroid dehydrogenase | 0.0013 | 0.0185 | 0.0035 |
Plasmodium falciparum | JmjC domain-containing protein, putative | 0.0018 | 0.047 | 0.1298 |
Echinococcus granulosus | caspase 2 | 0.0095 | 0.4746 | 0.4767 |
Echinococcus granulosus | oxidoreductase | 0.0013 | 0.0185 | 0.0179 |
Brugia malayi | oxidoreductase, short chain dehydrogenase/reductase family protein | 0.0013 | 0.0185 | 0.0185 |
Plasmodium falciparum | thioredoxin reductase | 0.0052 | 0.2384 | 1 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0049 | 0.2195 | 1 |
Echinococcus multilocularis | jumonji domain containing 1A | 0.0018 | 0.047 | 0.0466 |
Brugia malayi | Dehydrogenases, short chain protein 2 | 0.0013 | 0.0185 | 0.0185 |
Brugia malayi | oxidoreductase, short chain dehydrogenase/reductase family protein | 0.0013 | 0.0185 | 0.0185 |
Schistosoma mansoni | jumonji domain containing protein | 0.0068 | 0.3256 | 0.317 |
Schistosoma mansoni | tar DNA-binding protein | 0.007 | 0.3378 | 0.3295 |
Brugia malayi | PAS domain containing protein | 0.0056 | 0.26 | 0.26 |
Echinococcus granulosus | carbonyl reductase 1 | 0.0013 | 0.0185 | 0.0179 |
Brugia malayi | jmjC domain containing protein | 0.007 | 0.3358 | 0.3358 |
Echinococcus multilocularis | aryl hydrocarbon receptor | 0.0015 | 0.0274 | 0.0268 |
Schistosoma mansoni | carbonyl reductase | 0.0013 | 0.0185 | 0.0035 |
Schistosoma mansoni | aldehyde dehydrogenase | 0.0137 | 0.7138 | 0.7133 |
Trichomonas vaginalis | Clan CD, family C14, metacaspase-like cysteine peptidase | 0.0049 | 0.2195 | 1 |
Echinococcus multilocularis | cathepsin L cysteine protease | 0.0019 | 0.0493 | 0.0489 |
Echinococcus granulosus | inositol monophosphatase 1 | 0.0041 | 0.1743 | 0.1747 |
Loa Loa (eye worm) | hypothetical protein | 0.0012 | 0.0151 | 0.0144 |
Loa Loa (eye worm) | Papain cysteine protease/cathepsin propeptide inhibitor-containing protein | 0.0019 | 0.0493 | 0.0487 |
Loa Loa (eye worm) | hypothetical protein | 0.0013 | 0.0185 | 0.0178 |
Mycobacterium tuberculosis | Dihydrolipoamide dehydrogenase LpdC (lipoamide reductase (NADH)) (lipoyl dehydrogenase) (dihydrolipoyl dehydrogenase) (diaphoras | 0.0133 | 0.6879 | 0.9627 |
Loa Loa (eye worm) | inositol-1 | 0.0041 | 0.1743 | 0.1738 |
Giardia lamblia | NADH oxidase lateral transfer candidate | 0.0018 | 0.0471 | 0.0982 |
Brugia malayi | hypoxia-induced factor 1 | 0.0174 | 0.9183 | 0.9183 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0019 | 0.0493 | 0.1676 |
Schistosoma mansoni | aldehyde dehydrogenase | 0.0137 | 0.7138 | 0.7133 |
Trichomonas vaginalis | myo inositol monophosphatase, putative | 0.0041 | 0.1743 | 0.779 |
Schistosoma mansoni | cpg binding protein | 0.0034 | 0.1336 | 0.121 |
Trypanosoma cruzi | dihydrolipoamide dehydrogenase, putative | 0.0018 | 0.0471 | 0.089 |
Schistosoma mansoni | short chain dehydrogenase | 0.0013 | 0.0185 | 0.0035 |
Entamoeba histolytica | estradiol 17-beta-dehydrogenase, putative | 0.0013 | 0.0185 | 0.0212 |
Mycobacterium tuberculosis | Probable membrane NADH dehydrogenase NdhA | 0.0119 | 0.6134 | 0.8556 |
Loa Loa (eye worm) | hypothetical protein | 0.0013 | 0.0185 | 0.0178 |
Trichomonas vaginalis | hydroxyacyl dehydrogenase, putative | 0.0013 | 0.0185 | 0.0165 |
Schistosoma mansoni | caspase-7 (C14 family) | 0.0129 | 0.6697 | 0.6683 |
Trichomonas vaginalis | adenylate cyclase, type VII, putative | 0.0015 | 0.0274 | 0.0601 |
Onchocerca volvulus | 0.0013 | 0.0185 | 0.0074 | |
Echinococcus granulosus | lysine specific demethylase 5A | 0.007 | 0.3358 | 0.3371 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0019 | 0.0493 | 0.1676 |
Echinococcus multilocularis | caspase 8 | 0.0049 | 0.2195 | 0.2202 |
Schistosoma mansoni | steroid dehydrogenase | 0.0013 | 0.0185 | 0.0035 |
Trichomonas vaginalis | soluble guanylate cyclase gcy, putative | 0.0015 | 0.0274 | 0.0601 |
Entamoeba histolytica | cysteine proteinase, putative | 0.0019 | 0.0493 | 0.2152 |
Mycobacterium tuberculosis | Probable oxidoreductase | 0.0133 | 0.6879 | 0.9627 |
Loa Loa (eye worm) | hypothetical protein | 0.0095 | 0.4746 | 0.4742 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0019 | 0.0493 | 0.1676 |
Echinococcus multilocularis | phd:f box containing protein | 0.0018 | 0.047 | 0.0466 |
Trypanosoma cruzi | dihydrolipoamide dehydrogenase, putative | 0.0018 | 0.0471 | 0.089 |
Trypanosoma cruzi | STE group serine/threonine-protein kinase, putative | 0.0015 | 0.0274 | 0.0277 |
Onchocerca volvulus | Cathepsin L homolog | 0.0019 | 0.0493 | 0.0746 |
Toxoplasma gondii | aldehyde dehydrogenase | 0.0137 | 0.7138 | 1 |
Loa Loa (eye worm) | RNA recognition domain-containing protein domain-containing protein | 0.007 | 0.3378 | 0.3374 |
Mycobacterium tuberculosis | Probable dehydrogenase | 0.0119 | 0.6134 | 0.8556 |
Trichomonas vaginalis | short-chain dehydrogenase, putative | 0.0013 | 0.0185 | 0.0165 |
Trichomonas vaginalis | adenylate cyclase, putative | 0.0015 | 0.0274 | 0.0601 |
Schistosoma mansoni | 3-keto-dihydrosphingosine reductase | 0.0013 | 0.0185 | 0.0035 |
Echinococcus multilocularis | geminin | 0.0188 | 0.9946 | 1 |
Loa Loa (eye worm) | TAR-binding protein | 0.007 | 0.3378 | 0.3374 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L or K-like cysteine peptidase | 0.0019 | 0.0493 | 0.1676 |
Brugia malayi | oxidoreductase, short chain dehydrogenase/reductase family protein | 0.0013 | 0.0185 | 0.0185 |
Mycobacterium ulcerans | dihydrolipoamide dehydrogenase | 0.0018 | 0.0471 | 0.0412 |
Loa Loa (eye worm) | oxidoreductase | 0.0013 | 0.0185 | 0.0178 |
Schistosoma mansoni | dihydrolipoamide dehydrogenase | 0.0018 | 0.0471 | 0.0327 |
Toxoplasma gondii | histone lysine demethylase JMJC1/KDM5D/JARID1D | 0.0018 | 0.047 | 0.0411 |
Echinococcus multilocularis | retinol dehydrogenase 13 | 0.0013 | 0.0185 | 0.0179 |
Echinococcus multilocularis | Jumonji, AT rich interactive domain 1B | 0.002 | 0.0572 | 0.0568 |
Loa Loa (eye worm) | oxidoreductase | 0.0013 | 0.0185 | 0.0178 |
Plasmodium falciparum | metacaspase 1 | 0.0049 | 0.2195 | 0.9142 |
Leishmania major | metacaspase, putative | 0.0049 | 0.2195 | 0.2892 |
Schistosoma mansoni | short chain dehydrogenase | 0.0013 | 0.0185 | 0.0035 |
Trichomonas vaginalis | short-chain dehydrogenase, putative | 0.0013 | 0.0185 | 0.0165 |
Leishmania major | hypothetical protein, conserved | 0.0018 | 0.047 | 0.0411 |
Wolbachia endosymbiont of Brugia malayi | dihydrolipoamide dehydrogenase E3 component | 0.0018 | 0.0471 | 0.1839 |
Echinococcus multilocularis | cysteine protease | 0.0019 | 0.0493 | 0.0489 |
Toxoplasma gondii | exonuclease III APE | 0.0022 | 0.0672 | 0.0701 |
Loa Loa (eye worm) | hypothetical protein | 0.0013 | 0.0185 | 0.0178 |
Trypanosoma brucei | trypanothione reductase | 0.0052 | 0.2384 | 0.6827 |
Brugia malayi | Cathepsin L-like precursor | 0.0019 | 0.0493 | 0.0493 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0071 | 0.3406 | 1 |
Brugia malayi | Cathepsin L-like precursor | 0.0019 | 0.0493 | 0.0493 |
Plasmodium falciparum | glutathione reductase | 0.0018 | 0.0471 | 0.1303 |
Brugia malayi | Cell death protein 3 precursor | 0.0095 | 0.4746 | 0.4746 |
Echinococcus granulosus | hypothetical protein | 0.0013 | 0.0185 | 0.0179 |
Onchocerca volvulus | Dehydrogenase\/reductase SDR family member 13 homolog | 0.0013 | 0.0185 | 0.0074 |
Echinococcus granulosus | guanine nucleotide binding protein Gs subunit | 0.0053 | 0.2412 | 0.242 |
Echinococcus granulosus | Transcription factor JmjC domain containing protein | 0.0068 | 0.3256 | 0.3269 |
Mycobacterium tuberculosis | Probable reductase | 0.0119 | 0.6134 | 0.8556 |
Toxoplasma gondii | NADPH-glutathione reductase | 0.0018 | 0.0471 | 0.0412 |
Echinococcus multilocularis | cysteine protease | 0.0019 | 0.0493 | 0.0489 |
Loa Loa (eye worm) | dehydrogenase | 0.0013 | 0.0185 | 0.0178 |
Loa Loa (eye worm) | oxidoreductase | 0.0013 | 0.0185 | 0.0178 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0071 | 0.3406 | 1 |
Echinococcus granulosus | dihydrolipoamide dehydrogenase | 0.0018 | 0.0471 | 0.0467 |
Schistosoma mansoni | carbonyl reductase | 0.0013 | 0.0185 | 0.0035 |
Trypanosoma cruzi | myo-inositol-1(or 4)-monophosphatase 1, putative | 0.0041 | 0.1743 | 0.4839 |
Schistosoma mansoni | inositol monophosphatase | 0.0041 | 0.1743 | 0.1626 |
Trypanosoma cruzi | metacaspase, putative | 0.0049 | 0.2195 | 0.6242 |
Toxoplasma gondii | thioredoxin reductase | 0.0052 | 0.2384 | 0.3163 |
Plasmodium vivax | JmjC domain containing protein | 0.0018 | 0.047 | 0.1298 |
Plasmodium vivax | metacaspase 1, putative | 0.0049 | 0.2195 | 0.9142 |
Brugia malayi | exodeoxyribonuclease III family protein | 0.0022 | 0.0672 | 0.0672 |
Trypanosoma cruzi | major cysteine proteinase, putative | 0.0055 | 0.2561 | 0.7376 |
Trypanosoma cruzi | PAS-domain containing phosphoglycerate kinase, putative | 0.0015 | 0.0274 | 0.0277 |
Brugia malayi | oxidoreductase | 0.0013 | 0.0185 | 0.0185 |
Loa Loa (eye worm) | oxidoreductase | 0.0013 | 0.0185 | 0.0178 |
Brugia malayi | bHLH-PAS transcription factor | 0.0042 | 0.1783 | 0.1783 |
Loa Loa (eye worm) | glutathione reductase | 0.0052 | 0.2384 | 0.2379 |
Brugia malayi | jmjC domain containing protein | 0.0018 | 0.047 | 0.047 |
Schistosoma mansoni | short chain dehydrogenase | 0.0013 | 0.0185 | 0.0035 |
Leishmania major | apurinic/apyrimidinic endonuclease-redox protein | 0.0022 | 0.0672 | 0.0701 |
Brugia malayi | Fibroblast growth factor family protein | 0.0065 | 0.3105 | 0.3105 |
Schistosoma mansoni | jumonji/arid domain-containing protein | 0.007 | 0.3358 | 0.3274 |
Loa Loa (eye worm) | hypothetical protein | 0.0013 | 0.0185 | 0.0178 |
Brugia malayi | oxidoreductase, short chain dehydrogenase/reductase family protein | 0.0013 | 0.0185 | 0.0185 |
Echinococcus multilocularis | transfer RNA-Lys | 0.0042 | 0.1783 | 0.1787 |
Loa Loa (eye worm) | hypothetical protein | 0.0012 | 0.0151 | 0.0144 |
Schistosoma mansoni | tar DNA-binding protein | 0.007 | 0.3378 | 0.3295 |
Trichomonas vaginalis | short-chain dehydrogenase, putative | 0.0013 | 0.0185 | 0.0165 |
Trypanosoma brucei | inositol-1(or 4)-monophosphatase 1, putative | 0.0041 | 0.1743 | 0.4839 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0049 | 0.2195 | 1 |
Schistosoma mansoni | hypothetical protein | 0.0188 | 0.9946 | 1 |
Onchocerca volvulus | Dehydrogenase\/reductase SDR family member 1 homolog | 0.0013 | 0.0185 | 0.0074 |
Loa Loa (eye worm) | oxidoreductase | 0.0013 | 0.0185 | 0.0178 |
Trichomonas vaginalis | Clan CD, family C14, metacaspase-like cysteine peptidase | 0.0049 | 0.2195 | 1 |
Toxoplasma gondii | ICE family protease (caspase) p20 domain-containing protein | 0.0049 | 0.2195 | 0.2892 |
Wolbachia endosymbiont of Brugia malayi | exonuclease III | 0.0022 | 0.0672 | 0.3126 |
Echinococcus multilocularis | cathepsin L cysteine protease | 0.0019 | 0.0493 | 0.0489 |
Brugia malayi | 3-hydroxyacyl-CoA dehydrogenase type II | 0.0072 | 0.3497 | 0.3497 |
Entamoeba histolytica | myo-inositol monophosphatase, putative | 0.0041 | 0.1743 | 1 |
Entamoeba histolytica | short chain dehydrogenase family protein | 0.0013 | 0.0185 | 0.0212 |
Echinococcus granulosus | hypothetical protein | 0.0013 | 0.0185 | 0.0179 |
Echinococcus multilocularis | DNA (apurinic or apyrimidinic site) lyase | 0.0022 | 0.0672 | 0.0669 |
Brugia malayi | oxidoreductase, short chain dehydrogenase/reductase family protein | 0.0013 | 0.0185 | 0.0185 |
Giardia lamblia | Hypothetical protein | 0.0065 | 0.3105 | 1 |
Leishmania major | cathepsin L-like protease | 0.0071 | 0.3406 | 0.4633 |
Schistosoma mansoni | hypothetical protein | 0.0046 | 0.2007 | 0.1895 |
Loa Loa (eye worm) | aryl Hydrocarbon receptor Associated protein family member | 0.0015 | 0.0274 | 0.0267 |
Loa Loa (eye worm) | exodeoxyribonuclease III family protein | 0.0022 | 0.0672 | 0.0665 |
Trichomonas vaginalis | Clan CD, family C14, metacaspase-like cysteine peptidase | 0.0049 | 0.2195 | 1 |
Loa Loa (eye worm) | oxidoreductase | 0.0013 | 0.0185 | 0.0178 |
Mycobacterium ulcerans | exodeoxyribonuclease III protein XthA | 0.0022 | 0.0672 | 0.0701 |
Trypanosoma cruzi | dihydrolipoamide dehydrogenase, putative | 0.0018 | 0.0471 | 0.089 |
Leishmania major | 2-oxoglutarate dehydrogenase, e3 component, lipoamidedehydrogenase-like protein | 0.0018 | 0.0471 | 0.0412 |
Loa Loa (eye worm) | fibroinase | 0.0019 | 0.0493 | 0.0487 |
Toxoplasma gondii | ICE family protease (caspase) p20 domain-containing protein | 0.0049 | 0.2195 | 0.2892 |
Echinococcus granulosus | caspase 3 apoptosis cysteine peptidase | 0.0129 | 0.6697 | 0.6731 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0071 | 0.3406 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0013 | 0.0185 | 0.0178 |
Leishmania major | cathepsin L-like protease | 0.0019 | 0.0493 | 0.0444 |
Schistosoma mansoni | cpg binding protein | 0.0034 | 0.1336 | 0.121 |
Schistosoma mansoni | caspase-3 (C14 family) | 0.0129 | 0.6697 | 0.6683 |
Leishmania major | aldehyde dehydrogenase, mitochondrial precursor | 0.0137 | 0.7138 | 1 |
Onchocerca volvulus | 0.0015 | 0.0274 | 0.0267 | |
Toxoplasma gondii | inositol(myo)-1(or 4)-monophosphatase 2, putative | 0.0041 | 0.1743 | 0.2242 |
Onchocerca volvulus | 0.0013 | 0.0185 | 0.0074 | |
Onchocerca volvulus | 0.0019 | 0.0493 | 0.0746 | |
Plasmodium vivax | AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative | 0.0022 | 0.0672 | 0.2216 |
Trichomonas vaginalis | Clan CD, family C14, metacaspase-like cysteine peptidase | 0.0049 | 0.2195 | 1 |
Echinococcus multilocularis | lysine specific demethylase 5A | 0.0068 | 0.3256 | 0.3269 |
Trichomonas vaginalis | Clan CD, family C14, metacaspase-like cysteine peptidase | 0.0049 | 0.2195 | 1 |
Leishmania major | dihydrolipoamide dehydrogenase, putative | 0.0018 | 0.0471 | 0.0412 |
Echinococcus granulosus | carbonyl reductase 1 | 0.0013 | 0.0185 | 0.0179 |
Echinococcus granulosus | single minded 2 | 0.0042 | 0.1783 | 0.1787 |
Trypanosoma cruzi | metacaspase 5, putative | 0.0049 | 0.2195 | 0.6242 |
Toxoplasma gondii | cathepsin CPL | 0.0019 | 0.0493 | 0.0444 |
Trypanosoma cruzi | dihydrolipoyl dehydrogenase, putative | 0.0018 | 0.0471 | 0.089 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0019 | 0.0493 | 0.1676 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.0019 | 0.0493 | 0.1676 |
Trypanosoma brucei | dihydrolipoyl dehydrogenase | 0.0018 | 0.0471 | 0.089 |
Leishmania major | cathepsin L-like protease | 0.0071 | 0.3406 | 0.4633 |
Onchocerca volvulus | 0.0013 | 0.0185 | 0.0074 | |
Brugia malayi | dehydrogenases, short chain protein 9 | 0.0013 | 0.0185 | 0.0185 |
Loa Loa (eye worm) | hypothetical protein | 0.0065 | 0.3105 | 0.31 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.0019 | 0.0493 | 0.1676 |
Loa Loa (eye worm) | jmjC domain-containing protein | 0.0018 | 0.047 | 0.0463 |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.0053 | 0.2412 | 0.2308 |
Trypanosoma cruzi | dihydrolipoyl dehydrogenase, putative | 0.0018 | 0.0471 | 0.089 |
Echinococcus multilocularis | carbonyl reductase 1 | 0.0013 | 0.0185 | 0.0179 |
Onchocerca volvulus | Sepiapterin reductase homolog | 0.0013 | 0.0185 | 0.0074 |
Onchocerca volvulus | 0.0013 | 0.0185 | 0.0074 | |
Schistosoma mansoni | ap endonuclease | 0.0022 | 0.0672 | 0.0532 |
Plasmodium falciparum | metacaspase-like protein | 0.0049 | 0.2195 | 0.9142 |
Brugia malayi | dihydrolipoyl dehydrogenase, mitochondrial precursor, putative | 0.0018 | 0.0471 | 0.0471 |
Entamoeba histolytica | exodeoxyribonuclease III, putative | 0.0022 | 0.0672 | 0.3272 |
Onchocerca volvulus | 0.0032 | 0.1235 | 0.2359 | |
Schistosoma mansoni | inositol monophosphatase | 0.0041 | 0.1743 | 0.1626 |
Brugia malayi | alpha keto acid dehydrogenase complex, E3 component, lipoamide dehydrogenase | 0.0013 | 0.0202 | 0.0202 |
Schistosoma mansoni | steroid dehydrogenase | 0.0013 | 0.0185 | 0.0035 |
Brugia malayi | oxidoreductase, short chain dehydrogenase/reductase family protein | 0.0013 | 0.0185 | 0.0185 |
Entamoeba histolytica | cysteine proteinase, putative | 0.0019 | 0.0493 | 0.2152 |
Echinococcus multilocularis | caspase 3, apoptosis cysteine peptidase | 0.0129 | 0.6697 | 0.6731 |
Trichomonas vaginalis | Clan CD, family C14, metacaspase-like cysteine peptidase | 0.0049 | 0.2195 | 1 |
Leishmania major | cathepsin L-like protease | 0.0019 | 0.0493 | 0.0444 |
Echinococcus granulosus | cathepsin l1 | 0.0019 | 0.0493 | 0.0489 |
Schistosoma mansoni | ap endonuclease | 0.0022 | 0.0672 | 0.0532 |
Plasmodium falciparum | glutathione reductase | 0.0052 | 0.2384 | 1 |
Brugia malayi | Hypothetical oxidoreductase F56D1.5 | 0.0013 | 0.0185 | 0.0185 |
Echinococcus granulosus | retinol dehydrogenase 11 | 0.0013 | 0.0185 | 0.0179 |
Echinococcus granulosus | aryl hydrocarbon receptor | 0.0015 | 0.0274 | 0.0268 |
Onchocerca volvulus | Cell death protein 3 homolog | 0.0095 | 0.4746 | 1 |
Plasmodium vivax | vivapain-2 | 0.0019 | 0.0493 | 0.1404 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0071 | 0.3406 | 1 |
Schistosoma mansoni | short chain dehydrogenase | 0.0013 | 0.0185 | 0.0035 |
Trypanosoma brucei | metacaspase | 0.0049 | 0.2195 | 0.6242 |
Trypanosoma cruzi | cysteine peptidase, putative | 0.0071 | 0.3406 | 1 |
Brugia malayi | mucosa associated lymphoid tissue lymphoma translocation protein 1 | 0.0049 | 0.2195 | 0.2195 |
Schistosoma mansoni | mixed-lineage leukemia protein mll | 0.0067 | 0.3228 | 0.3141 |
Trypanosoma cruzi | metacaspase, putative | 0.0049 | 0.2195 | 0.6242 |
Leishmania major | cysteine peptidase A (CPA) | 0.0019 | 0.0493 | 0.0444 |
Trypanosoma brucei | metacaspase 5, putative | 0.0049 | 0.2195 | 0.6242 |
Trypanosoma cruzi | dihydrolipoamide dehydrogenase, putative | 0.0018 | 0.0471 | 0.089 |
Loa Loa (eye worm) | hypothetical protein | 0.0013 | 0.0185 | 0.0178 |
Schistosoma mansoni | steroid dehydrogenase | 0.0013 | 0.0185 | 0.0035 |
Mycobacterium leprae | DIHYDROLIPOAMIDE DEHYDROGENASE LPD (LIPOAMIDE REDUCTASE (NADH)) (LIPOYL DEHYDROGENASE) (DIHYDROLIPOYL DEHYDROGENASE) (DIAPHORASE | 0.0133 | 0.6879 | 1 |
Trypanosoma cruzi | myo-inositol-1(or 4)-monophosphatase 1, putative | 0.0041 | 0.1743 | 0.4839 |
Brugia malayi | RNA recognition motif domain containing protein | 0.007 | 0.3378 | 0.3378 |
Trypanosoma cruzi | metacaspase 5, putative | 0.0049 | 0.2195 | 0.6242 |
Echinococcus multilocularis | retinol dehydrogenase 11 | 0.0013 | 0.0185 | 0.0179 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.0019 | 0.0493 | 0.1676 |
Echinococcus multilocularis | conserved hypothetical protein | 0.0013 | 0.0185 | 0.0179 |
Brugia malayi | Cathepsin L-like cysteine proteinase | 0.0012 | 0.0151 | 0.0151 |
Activity type | Activity value | Assay description | Source | Reference |
---|---|---|---|---|
Kd (binding) | = 4.84 uM | Binding affinity for human fibroblast growth factor 1 in surface plasmon resonance (SPR) assay | ChEMBL. | 15081013 |
Kd (binding) | = 16 uM | Binding affinity for human fibroblast growth factor 2 in surface plasmon resonance (SPR) assay | ChEMBL. | 15081013 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.
1 literature reference was collected for this gene.