Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Leishmania major | heat shock protein 83-1 | 0.0036 | 0.0224 | 0.0142 |
Trichomonas vaginalis | myo inositol monophosphatase, putative | 0.0043 | 0.0304 | 0.0675 |
Mycobacterium tuberculosis | Inositol-1-monophosphatase SuhB | 0.0039 | 0.025 | 0.0318 |
Leishmania major | heat shock protein 83-1 | 0.0036 | 0.0224 | 0.0142 |
Schistosoma mansoni | zinc finger protein | 0.002 | 0.0032 | 0.0034 |
Brugia malayi | Bromodomain containing protein | 0.004 | 0.0268 | 0.0366 |
Brugia malayi | Calcitonin receptor-like protein seb-1 | 0.0051 | 0.0406 | 0.0583 |
Entamoeba histolytica | myo-inositol monophosphatase, putative | 0.0043 | 0.0304 | 0.0481 |
Onchocerca volvulus | 0.0082 | 0.0777 | 0.2414 | |
Trypanosoma cruzi | hexokinase, putative | 0.0082 | 0.0777 | 0.1149 |
Loa Loa (eye worm) | hexokinase | 0.0025 | 0.0092 | 0.0132 |
Schistosoma mansoni | hypothetical protein | 0.0035 | 0.021 | 0.0221 |
Brugia malayi | Polyprenyl synthetase family protein | 0.0174 | 0.1888 | 0.2903 |
Echinococcus multilocularis | hexokinase | 0.0082 | 0.0777 | 0.0777 |
Trichomonas vaginalis | alpha-galactosidase/alpha-N-acetylgalactosaminidase, putative | 0.0077 | 0.0708 | 0.1766 |
Echinococcus multilocularis | heat shock protein 90 | 0.0029 | 0.0135 | 0.0135 |
Echinococcus multilocularis | histone acetyltransferase MYST2 | 0.0057 | 0.0469 | 0.0469 |
Mycobacterium tuberculosis | Probable geranylgeranyl pyrophosphate synthetase IdsA2 (ggppsase) (GGPP synthetase) (geranylgeranyl diphosphate synthase) | 0.0329 | 0.3753 | 1 |
Echinococcus granulosus | heat shock protein 90 | 0.0029 | 0.0135 | 0.0142 |
Mycobacterium tuberculosis | Possible polyprenyl synthetase IdsB (polyprenyl transferase) (polyprenyl diphosphate synthase) | 0.0174 | 0.1888 | 0.4845 |
Leishmania major | heat shock protein 83-1 | 0.0036 | 0.0224 | 0.0142 |
Schistosoma mansoni | histone-lysine n-methyltransferase suv9 | 0.0035 | 0.0205 | 0.0216 |
Echinococcus multilocularis | endoplasmin | 0.0029 | 0.0135 | 0.0135 |
Trypanosoma cruzi | solanesyl-diphosphate synthase, putative | 0.0174 | 0.1888 | 0.2891 |
Echinococcus granulosus | heat shock protein | 0.0036 | 0.0224 | 0.0236 |
Echinococcus multilocularis | Polycystic kidney disease protein | 0.0021 | 0.0034 | 0.0034 |
Echinococcus granulosus | histone lysine methyltransferase setb | 0.0053 | 0.0419 | 0.0442 |
Schistosoma mansoni | scm-relatedprotein containing 4 mbt domains (sfmbt) | 0.005 | 0.0386 | 0.0407 |
Echinococcus multilocularis | heat shock protein | 0.0036 | 0.0224 | 0.0224 |
Leishmania major | polyprenyl synthase, putative | 0.055 | 0.6421 | 1 |
Treponema pallidum | octaprenyl-diphosphate synthase | 0.055 | 0.6421 | 1 |
Trypanosoma cruzi | myo-inositol-1(or 4)-monophosphatase 1, putative | 0.0043 | 0.0304 | 0.0408 |
Loa Loa (eye worm) | hexokinase type II | 0.0082 | 0.0777 | 0.12 |
Echinococcus granulosus | hexokinase | 0.0082 | 0.0777 | 0.0819 |
Brugia malayi | hexokinase type II | 0.0026 | 0.0101 | 0.0105 |
Brugia malayi | MH2 domain containing protein | 0.0122 | 0.1256 | 0.1914 |
Trichomonas vaginalis | heat shock protein, putative | 0.0029 | 0.0135 | 0.0217 |
Loa Loa (eye worm) | pre-SET domain-containing protein family protein | 0.0243 | 0.271 | 0.4213 |
Mycobacterium ulcerans | extragenic suppressor protein SuhB | 0.0043 | 0.0304 | 0.0468 |
Loa Loa (eye worm) | pigment dispersing factor receptor c | 0.0051 | 0.0406 | 0.0621 |
Trypanosoma cruzi | Heat shock protein 83, putative | 0.0036 | 0.0224 | 0.0282 |
Echinococcus granulosus | 5'partial|histone lysine N methyltransferase SETDB2 | 0.0034 | 0.0189 | 0.02 |
Leishmania major | heat shock protein 83-1 | 0.0036 | 0.0224 | 0.0142 |
Schistosoma mansoni | histone-lysine n-methyltransferase setb1 | 0.0053 | 0.0419 | 0.0442 |
Echinococcus granulosus | suppression of tumorigenicity 18 protein | 0.0057 | 0.0469 | 0.0495 |
Loa Loa (eye worm) | hypothetical protein | 0.0156 | 0.1667 | 0.2587 |
Trypanosoma cruzi | hexokinase, putative | 0.0082 | 0.0777 | 0.1149 |
Loa Loa (eye worm) | polyprenyl synthetase | 0.0329 | 0.3753 | 0.584 |
Brugia malayi | mbt repeat family protein | 0.005 | 0.0386 | 0.0552 |
Brugia malayi | heat shock protein 90 | 0.0036 | 0.0224 | 0.0298 |
Schistosoma mansoni | myelin transcription factor 1 myt1 | 0.0057 | 0.0469 | 0.0495 |
Onchocerca volvulus | Polycomb protein Sfmbt homolog | 0.005 | 0.0386 | 0.1144 |
Entamoeba histolytica | bifunctional short chain isoprenyl diphosphate synthase, putative | 0.0174 | 0.1888 | 1 |
Schistosoma mansoni | glutathione synthetase | 0.0174 | 0.1888 | 0.1991 |
Plasmodium vivax | octaprenyl pyrophosphate synthase, putative | 0.0174 | 0.1888 | 0.4986 |
Mycobacterium ulcerans | geranylgeranyl pyrophosphate synthase | 0.0329 | 0.3753 | 1 |
Schistosoma mansoni | sex comb on midleg homolog | 0.005 | 0.0386 | 0.0407 |
Trichomonas vaginalis | geranylgeranyl pyrophosphate synthase, putative | 0.0329 | 0.3753 | 1 |
Plasmodium falciparum | octaprenyl pyrophosphate synthase | 0.0174 | 0.1888 | 0.4986 |
Echinococcus multilocularis | suppression of tumorigenicity 18 protein | 0.0057 | 0.0469 | 0.0469 |
Onchocerca volvulus | 0.0082 | 0.0777 | 0.2414 | |
Trypanosoma brucei | hexokinase, putative | 0.0082 | 0.0777 | 0.1567 |
Echinococcus multilocularis | arachidonate 5 lipoxygenase | 0.0058 | 0.0481 | 0.0481 |
Schistosoma mansoni | heat shock protein | 0.0036 | 0.0224 | 0.0236 |
Leishmania major | heat shock protein 83-1 | 0.0036 | 0.0224 | 0.0142 |
Loa Loa (eye worm) | hypothetical protein | 0.0053 | 0.0419 | 0.0642 |
Echinococcus multilocularis | geminin | 0.0177 | 0.192 | 0.192 |
Schistosoma mansoni | hypothetical protein | 0.0177 | 0.192 | 0.2025 |
Trichomonas vaginalis | heat shock protein, putative | 0.0029 | 0.0135 | 0.0217 |
Plasmodium falciparum | endoplasmin, putative | 0.0022 | 0.0054 | 0.0056 |
Toxoplasma gondii | V-type H(+)-translocating pyrophosphatase VP1 | 0.0325 | 0.3708 | 0.9872 |
Echinococcus multilocularis | fetal alzheimer antigen, falz | 0.0024 | 0.0069 | 0.0069 |
Loa Loa (eye worm) | hypothetical protein | 0.0026 | 0.0101 | 0.0145 |
Loa Loa (eye worm) | transcription factor SMAD2 | 0.0122 | 0.1256 | 0.1946 |
Echinococcus multilocularis | heat shock protein 90 | 0.0036 | 0.0224 | 0.0224 |
Echinococcus granulosus | hexokinase type 2 | 0.0082 | 0.0777 | 0.0819 |
Schistosoma mansoni | heat shock protein | 0.0036 | 0.0224 | 0.0236 |
Schistosoma mansoni | sex comb on midleg homolog | 0.005 | 0.0386 | 0.0407 |
Schistosoma mansoni | alpha-galactosidase/alpha-n-acetylgalactosaminidase | 0.0115 | 0.1169 | 0.1233 |
Leishmania major | heat shock protein 83-1 | 0.0036 | 0.0224 | 0.0142 |
Echinococcus multilocularis | bromodomain adjacent to zinc finger domain | 0.0062 | 0.0537 | 0.0537 |
Plasmodium vivax | V-type H(+)-translocating pyrophosphatase, putative | 0.0325 | 0.3708 | 0.9878 |
Echinococcus granulosus | arachidonate 5 lipoxygenase | 0.0058 | 0.0481 | 0.0507 |
Brugia malayi | Hexokinase family protein | 0.0082 | 0.0777 | 0.1164 |
Toxoplasma gondii | heat shock protein HSP90 | 0.0036 | 0.0224 | 0.0055 |
Schistosoma mansoni | hypothetical protein | 0.0303 | 0.3438 | 0.3626 |
Schistosoma mansoni | microtubule-associated protein tau | 0.0804 | 0.9482 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0043 | 0.0298 | 0.0453 |
Wolbachia endosymbiont of Brugia malayi | geranylgeranyl pyrophosphate synthase | 0.0174 | 0.1888 | 1 |
Loa Loa (eye worm) | hexokinase | 0.0082 | 0.0777 | 0.12 |
Brugia malayi | mbt repeat family protein | 0.005 | 0.0386 | 0.0552 |
Mycobacterium tuberculosis | Probable polyprenyl-diphosphate synthase GrcC2 (polyprenyl pyrophosphate synthetase) | 0.0174 | 0.1888 | 0.4845 |
Mycobacterium tuberculosis | Probable multifunctional geranylgeranyl pyrophosphate synthetase IdsA1 (GGPP synthetase) (ggppsase) (geranylgeranyl diphosphate | 0.0174 | 0.1888 | 0.4845 |
Schistosoma mansoni | hypothetical protein | 0.0177 | 0.192 | 0.2025 |
Schistosoma mansoni | loxhd1 | 0.0021 | 0.0034 | 0.0035 |
Schistosoma mansoni | alpha-galactosidase/alpha-n-acetylgalactosaminidase | 0.0115 | 0.1169 | 0.1233 |
Loa Loa (eye worm) | heat shock protein 90 | 0.0036 | 0.0224 | 0.0338 |
Leishmania major | myo-inositol-1(or 4)-monophosphatase 1, putative | 0.0043 | 0.0304 | 0.0269 |
Leishmania major | heat shock protein 83-1 | 0.0036 | 0.0224 | 0.0142 |
Echinococcus multilocularis | lipoxygenase domain containing protein | 0.0021 | 0.0034 | 0.0034 |
Trichomonas vaginalis | geranylgeranyl pyrophosphate synthase, putative | 0.0329 | 0.3753 | 1 |
Echinococcus granulosus | zinc finger protein | 0.002 | 0.0032 | 0.0034 |
Echinococcus granulosus | hexokinase | 0.0082 | 0.0777 | 0.0819 |
Echinococcus granulosus | muscleblind protein | 0.0156 | 0.1667 | 0.1758 |
Trypanosoma cruzi | heat shock protein 90, putative | 0.0036 | 0.0224 | 0.0282 |
Loa Loa (eye worm) | hexokinase | 0.0052 | 0.0407 | 0.0623 |
Onchocerca volvulus | 0.0082 | 0.0777 | 0.2414 | |
Loa Loa (eye worm) | hypothetical protein | 0.005 | 0.0386 | 0.059 |
Trypanosoma brucei | inositol-1(or 4)-monophosphatase 1, putative | 0.0043 | 0.0304 | 0.0227 |
Mycobacterium leprae | possible inositol monophosphatase SubH (IMPase) (inositol-1-phosphatase) (I-1-Pase ). | 0.0039 | 0.025 | 0.0656 |
Toxoplasma gondii | inositol(myo)-1(or 4)-monophosphatase 2, putative | 0.0043 | 0.0304 | 0.0281 |
Schistosoma mansoni | rab6-interacting | 0.0021 | 0.0034 | 0.0035 |
Leishmania major | farnesyl pyrophosphate synthase | 0.0329 | 0.3753 | 0.5756 |
Schistosoma mansoni | lipoxygenase | 0.0058 | 0.0481 | 0.0507 |
Leishmania major | heat shock protein 83-1 | 0.0036 | 0.0224 | 0.0142 |
Giardia lamblia | Farnesyl diphosphate synthase | 0.0329 | 0.3753 | 1 |
Plasmodium falciparum | heat shock protein 90 | 0.0036 | 0.0224 | 0.0513 |
Echinococcus granulosus | bromodomain adjacent to zinc finger domain | 0.0062 | 0.0537 | 0.0567 |
Leishmania major | heat shock protein 83-1 | 0.0036 | 0.0224 | 0.0142 |
Brugia malayi | Pre-SET motif family protein | 0.0035 | 0.0205 | 0.0268 |
Brugia malayi | Pre-SET motif family protein | 0.0243 | 0.271 | 0.419 |
Loa Loa (eye worm) | hypothetical protein | 0.0051 | 0.0406 | 0.0621 |
Trypanosoma brucei | solanesyl-diphosphate synthase, putative | 0.0174 | 0.1888 | 0.4715 |
Brugia malayi | Bromodomain containing protein | 0.0078 | 0.073 | 0.109 |
Trypanosoma brucei | hexokinase | 0.0082 | 0.0777 | 0.1567 |
Echinococcus multilocularis | muscleblind protein 1 | 0.0156 | 0.1667 | 0.1667 |
Echinococcus granulosus | inositol monophosphatase 1 | 0.0043 | 0.0304 | 0.0321 |
Schistosoma mansoni | hexokinase | 0.0082 | 0.0777 | 0.0819 |
Echinococcus multilocularis | bromodomain adjacent to zinc finger domain | 0.0038 | 0.0238 | 0.0238 |
Trichomonas vaginalis | heat shock protein, putative | 0.0036 | 0.0224 | 0.0459 |
Echinococcus granulosus | Polycystic kidney disease protein | 0.0021 | 0.0034 | 0.0035 |
Trypanosoma cruzi | myo-inositol-1(or 4)-monophosphatase 1, putative | 0.0043 | 0.0304 | 0.0408 |
Echinococcus multilocularis | neuropeptide s receptor | 0.0483 | 0.561 | 0.561 |
Schistosoma mansoni | inositol monophosphatase | 0.0043 | 0.0304 | 0.0321 |
Loa Loa (eye worm) | MH2 domain-containing protein | 0.0122 | 0.1256 | 0.1946 |
Toxoplasma gondii | polyprenyl synthetase superfamily protein | 0.0329 | 0.3753 | 1 |
Leishmania major | heat shock protein 83-1 | 0.0036 | 0.0224 | 0.0142 |
Echinococcus multilocularis | endonuclease exonuclease phosphatase | 0.0196 | 0.2153 | 0.2153 |
Chlamydia trachomatis | geranylgeranyl pyrophosphate synthase | 0.0174 | 0.1888 | 0.5 |
Echinococcus multilocularis | Alpha N acetylgalactosaminidase | 0.0115 | 0.1169 | 0.1169 |
Trypanosoma brucei | Pyrophosphate-energized vacuolar membrane proton pump 2, putative | 0.0325 | 0.3708 | 0.9871 |
Echinococcus granulosus | RUN | 0.0021 | 0.0034 | 0.0035 |
Plasmodium vivax | geranylgeranyl pyrophosphate synthase | 0.0329 | 0.3753 | 1 |
Loa Loa (eye worm) | hexokinase | 0.0082 | 0.0777 | 0.12 |
Loa Loa (eye worm) | hypothetical protein | 0.0021 | 0.0034 | 0.004 |
Echinococcus granulosus | heat shock protein heat shock protein 90 alpha | 0.0029 | 0.0135 | 0.0142 |
Trypanosoma cruzi | heat shock protein 85, putative | 0.0036 | 0.0224 | 0.0282 |
Loa Loa (eye worm) | polyprenyl synthetase | 0.0174 | 0.1888 | 0.2932 |
Echinococcus multilocularis | hexokinase | 0.0082 | 0.0777 | 0.0777 |
Schistosoma mansoni | alpha-galactosidase/alpha-n-acetylgalactosaminidase | 0.0115 | 0.1169 | 0.1233 |
Echinococcus multilocularis | SAM and MBT domain containing protein | 0.005 | 0.0386 | 0.0386 |
Leishmania major | heat shock protein 83-1 | 0.0036 | 0.0224 | 0.0142 |
Brugia malayi | Hexokinase family protein | 0.0025 | 0.0092 | 0.0092 |
Echinococcus granulosus | bromodomain adjacent to zinc finger domain | 0.0038 | 0.0238 | 0.0251 |
Trichomonas vaginalis | myo inositol monophosphatase, putative | 0.0043 | 0.0304 | 0.0675 |
Loa Loa (eye worm) | MBCTL1 | 0.0057 | 0.0469 | 0.072 |
Echinococcus multilocularis | hexokinase type 2 | 0.0082 | 0.0777 | 0.0777 |
Onchocerca volvulus | 0.0035 | 0.0205 | 0.0556 | |
Mycobacterium ulcerans | polyprenyl synthetase IdsB | 0.0174 | 0.1888 | 0.4845 |
Loa Loa (eye worm) | hypothetical protein | 0.004 | 0.0269 | 0.0407 |
Brugia malayi | Hexokinase family protein | 0.0052 | 0.0407 | 0.0585 |
Plasmodium falciparum | geranylgeranyl pyrophosphate synthase, putative | 0.0329 | 0.3753 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0077 | 0.0708 | 0.1092 |
Brugia malayi | Polyprenyl synthetase family protein | 0.0329 | 0.3753 | 0.5823 |
Toxoplasma gondii | polyprenyl synthetase superfamily protein | 0.0174 | 0.1888 | 0.4744 |
Leishmania major | heat shock protein 83-1 | 0.0036 | 0.0224 | 0.0142 |
Loa Loa (eye worm) | hypothetical protein | 0.0026 | 0.0101 | 0.0145 |
Trypanosoma brucei | Pyrophosphate-energized vacuolar membrane proton pump 1 | 0.0325 | 0.3708 | 0.9871 |
Echinococcus granulosus | farnesyl pyrophosphate synthase | 0.0329 | 0.3753 | 0.3958 |
Toxoplasma gondii | heat shock protein 90, putative | 0.0036 | 0.0224 | 0.0055 |
Plasmodium vivax | heat shock protein 86, putative | 0.0036 | 0.0224 | 0.0513 |
Loa Loa (eye worm) | hypothetical protein | 0.0045 | 0.0322 | 0.0491 |
Echinococcus granulosus | histone acetyltransferase MYST2 | 0.0057 | 0.0469 | 0.0495 |
Echinococcus multilocularis | zinc finger protein | 0.002 | 0.0032 | 0.0032 |
Trichomonas vaginalis | heat shock protein, putative | 0.0029 | 0.0135 | 0.0217 |
Schistosoma mansoni | geranylgeranyl pyrophosphate synthase | 0.055 | 0.6421 | 0.6772 |
Schistosoma mansoni | trans-prenyltransferase | 0.0174 | 0.1888 | 0.1991 |
Loa Loa (eye worm) | hypothetical protein | 0.0035 | 0.021 | 0.0315 |
Echinococcus multilocularis | Glycoside hydrolase, family 27 | 0.0115 | 0.1169 | 0.1169 |
Echinococcus multilocularis | prenyl (decaprenyl) diphosphate synthase | 0.0174 | 0.1888 | 0.1888 |
Brugia malayi | Muscleblind-like protein | 0.0156 | 0.1667 | 0.2557 |
Brugia malayi | latrophilin 2 splice variant baaae | 0.0035 | 0.021 | 0.0276 |
Schistosoma mansoni | inositol monophosphatase | 0.0043 | 0.0304 | 0.0321 |
Brugia malayi | Inositol-1 | 0.0043 | 0.0304 | 0.0424 |
Brugia malayi | geranylgeranyl pyrophosphate synthetase | 0.055 | 0.6421 | 1 |
Schistosoma mansoni | histone-lysine n-methyltransferase setb1 | 0.0035 | 0.0205 | 0.0216 |
Echinococcus multilocularis | geranylgeranyl pyrophosphate synthase | 0.055 | 0.6421 | 0.6421 |
Toxoplasma gondii | hexokinase | 0.0082 | 0.0777 | 0.1613 |
Onchocerca volvulus | 0.005 | 0.0386 | 0.1144 | |
Mycobacterium ulcerans | geranylgeranyl pyrophosphate synthase | 0.0329 | 0.3753 | 1 |
Leishmania major | hexokinase, putative | 0.0082 | 0.0777 | 0.1022 |
Loa Loa (eye worm) | endoplasmin | 0.0036 | 0.0224 | 0.0338 |
Trypanosoma cruzi | solanesyl-diphosphate synthase, putative | 0.0174 | 0.1888 | 0.2891 |
Leishmania major | heat shock protein 83-1 | 0.0036 | 0.0224 | 0.0142 |
Schistosoma mansoni | lipoxygenase | 0.0021 | 0.0034 | 0.0035 |
Echinococcus multilocularis | neuropeptide receptor A26 | 0.0483 | 0.561 | 0.561 |
Schistosoma mansoni | endoplasmin | 0.0036 | 0.0224 | 0.0236 |
Leishmania major | heat shock protein 83-1 | 0.0036 | 0.0224 | 0.0142 |
Trypanosoma cruzi | heat shock protein 85, putative | 0.0036 | 0.0224 | 0.0282 |
Echinococcus multilocularis | histone lysine methyltransferase setb histone lysine methyltransferase eggless | 0.0053 | 0.0419 | 0.0419 |
Trypanosoma cruzi | vacuolar-type proton translocating pyrophosphatase 1 | 0.0325 | 0.3708 | 0.5745 |
Onchocerca volvulus | Hexokinase homolog | 0.0052 | 0.0407 | 0.1214 |
Mycobacterium ulcerans | polyprenyl diphosphate synthetase, GrcC1 | 0.0174 | 0.1888 | 0.4845 |
Trypanosoma cruzi | Vacuolar proton pyrophosphatase 1, putative | 0.0325 | 0.3708 | 0.5745 |
Giardia lamblia | Heat shock protein HSP 90-alpha | 0.0036 | 0.0224 | 0.0247 |
Echinococcus granulosus | prenyl decaprenyl diphosphate synthase | 0.0174 | 0.1888 | 0.1991 |
Trichomonas vaginalis | inositol monophosphatase, putative | 0.0043 | 0.0304 | 0.0675 |
Echinococcus granulosus | lipoxygenase domain containing protein | 0.0021 | 0.0034 | 0.0035 |
Entamoeba histolytica | geranylgeranyl pyrophosphate synthase, putative | 0.0174 | 0.1888 | 1 |
Entamoeba histolytica | geranylgeranyl pyrophosphate synthetase, putative | 0.0174 | 0.1888 | 1 |
Trichomonas vaginalis | set domain proteins, putative | 0.0276 | 0.3114 | 0.8272 |
Plasmodium vivax | endoplasmin, putative | 0.0036 | 0.0224 | 0.0513 |
Plasmodium falciparum | hexokinase | 0.0082 | 0.0777 | 0.1999 |
Trypanosoma brucei | farnesyl pyrophosphate synthase | 0.0329 | 0.3753 | 1 |
Echinococcus granulosus | heat shock protein 90 | 0.0036 | 0.0224 | 0.0236 |
Brugia malayi | hypothetical protein | 0.0169 | 0.1826 | 0.2807 |
Echinococcus multilocularis | microtubule associated protein 2 | 0.0804 | 0.9482 | 0.9482 |
Schistosoma mansoni | farnesyl pyrophosphate synthase | 0.0329 | 0.3753 | 0.3958 |
Loa Loa (eye worm) | hypothetical protein | 0.0169 | 0.1826 | 0.2836 |
Trypanosoma cruzi | polyprenyl synthase, putative | 0.055 | 0.6421 | 1 |
Loa Loa (eye worm) | doublecortin family protein | 0.0021 | 0.0034 | 0.004 |
Echinococcus granulosus | neuropeptide receptor A26 | 0.0483 | 0.561 | 0.5917 |
Schistosoma mansoni | rab6-interacting | 0.0021 | 0.0034 | 0.0035 |
Echinococcus granulosus | geranylgeranyl pyrophosphate synthase | 0.055 | 0.6421 | 0.6772 |
Echinococcus granulosus | neuropeptide s receptor | 0.0483 | 0.561 | 0.5917 |
Echinococcus granulosus | decaprenyl diphosphate synthase subunit 1 | 0.0174 | 0.1888 | 0.1991 |
Entamoeba histolytica | hexokinase 2 | 0.0082 | 0.0777 | 0.3323 |
Leishmania major | heat shock protein 83-1 | 0.0036 | 0.0224 | 0.0142 |
Plasmodium falciparum | V-type K+-independent H+-translocating inorganic pyrophosphatase | 0.0325 | 0.3708 | 0.9878 |
Echinococcus granulosus | hexokinase | 0.0082 | 0.0777 | 0.0819 |
Echinococcus granulosus | endonuclease exonuclease phosphatase | 0.0196 | 0.2153 | 0.2271 |
Loa Loa (eye worm) | geranylgeranyl pyrophosphate synthetase | 0.055 | 0.6421 | 1 |
Echinococcus granulosus | fetal alzheimer antigen falz | 0.0024 | 0.0069 | 0.0073 |
Trypanosoma brucei | hexokinase | 0.0082 | 0.0777 | 0.1567 |
Loa Loa (eye worm) | hypothetical protein | 0.0156 | 0.1667 | 0.2587 |
Echinococcus multilocularis | muscleblind protein | 0.0156 | 0.1667 | 0.1667 |
Schistosoma mansoni | polycystin 1-related | 0.0021 | 0.0034 | 0.0035 |
Toxoplasma gondii | melibiase subfamily protein | 0.0115 | 0.1169 | 0.2717 |
Schistosoma mansoni | alpha-galactosidase/alpha-n-acetylgalactosaminidase | 0.0115 | 0.1169 | 0.1233 |
Echinococcus multilocularis | lipoxygenase domain containing protein | 0.0021 | 0.0034 | 0.0034 |
Brugia malayi | C2-HC type zinc finger protein C.e-MyT1 | 0.0057 | 0.0469 | 0.0682 |
Trypanosoma cruzi | heat shock protein 90, putative | 0.0029 | 0.0135 | 0.0142 |
Trypanosoma cruzi | solanesyl-diphosphate synthase | 0.0174 | 0.1888 | 0.2891 |
Trypanosoma cruzi | farnesyl pyrophosphate synthase | 0.0329 | 0.3753 | 0.5816 |
Onchocerca volvulus | 0.0052 | 0.0407 | 0.1214 | |
Echinococcus granulosus | endoplasmin | 0.0029 | 0.0135 | 0.0142 |
Echinococcus multilocularis | farnesyl pyrophosphate synthase | 0.0329 | 0.3753 | 0.3753 |
Brugia malayi | PHD-finger family protein | 0.0026 | 0.0099 | 0.0102 |
Plasmodium vivax | SET domain protein, putative | 0.0035 | 0.0205 | 0.046 |
Schistosoma mansoni | endoplasmin | 0.0036 | 0.0224 | 0.0236 |
Schistosoma mansoni | bromodomain containing protein | 0.0066 | 0.0582 | 0.0614 |
Onchocerca volvulus | 0.0276 | 0.3114 | 1 | |
Schistosoma mansoni | hypothetical protein | 0.0021 | 0.0034 | 0.0035 |
Trypanosoma cruzi | heat shock protein 85, putative | 0.0036 | 0.0224 | 0.0282 |
Onchocerca volvulus | 0.0169 | 0.1826 | 0.582 | |
Leishmania major | heat shock protein 83-1 | 0.0036 | 0.0224 | 0.0142 |
Brugia malayi | Melibiase family protein | 0.0077 | 0.0708 | 0.1056 |
Loa Loa (eye worm) | PHD-finger family protein | 0.0022 | 0.0045 | 0.0058 |
Schistosoma mansoni | alpha-galactosidase/alpha-n-acetylgalactosaminidase | 0.0077 | 0.0708 | 0.0746 |
Brugia malayi | hexokinase | 0.0082 | 0.0777 | 0.1164 |
Echinococcus granulosus | SAM and MBT domain containing protein | 0.005 | 0.0386 | 0.0407 |
Echinococcus granulosus | geminin | 0.0177 | 0.192 | 0.2025 |
Schistosoma mansoni | acetyl-CoA C-acetyltransferase | 0.0024 | 0.0069 | 0.0073 |
Brugia malayi | Corticotropin releasing factor receptor 2 precursor, putative | 0.0051 | 0.0406 | 0.0583 |
Plasmodium vivax | hexokinase, putative | 0.0082 | 0.0777 | 0.1999 |
Trypanosoma cruzi | polyprenyl synthase, putative | 0.055 | 0.6421 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0057 | 0.0469 | 0.072 |
Loa Loa (eye worm) | inositol-1 | 0.0043 | 0.0304 | 0.0462 |
Plasmodium vivax | vacuolar-type H+ pumping pyrophosphatase, putative | 0.0325 | 0.3708 | 0.9878 |
Schistosoma mansoni | hypothetical protein | 0.0022 | 0.0045 | 0.0048 |
Leishmania major | heat shock protein 83-1 | 0.0036 | 0.0224 | 0.0142 |
Loa Loa (eye worm) | hypothetical protein | 0.0021 | 0.0034 | 0.004 |
Schistosoma mansoni | histone-lysine n-methyltransferase setb1 | 0.0053 | 0.0419 | 0.0442 |
Entamoeba histolytica | hexokinase 1 | 0.0082 | 0.0777 | 0.3323 |
Wolbachia endosymbiont of Brugia malayi | fructose-1,6-bisphosphatase | 0.0043 | 0.0304 | 0.0966 |
Trichomonas vaginalis | geranylgeranyl diphosphate synthase, putative | 0.0329 | 0.3753 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0074 | 0.0676 | 0.1042 |
Echinococcus multilocularis | RUN | 0.0021 | 0.0034 | 0.0034 |
Schistosoma mansoni | alpha-galactosidase/alpha-n-acetylgalactosaminidase | 0.0077 | 0.0708 | 0.0746 |
Loa Loa (eye worm) | hypothetical protein | 0.0056 | 0.0462 | 0.0708 |
Echinococcus multilocularis | histone lysine N methyltransferase SETMAR | 0.0035 | 0.0205 | 0.0205 |
Leishmania major | hexokinase, putative | 0.0082 | 0.0777 | 0.1022 |
Trypanosoma cruzi | farnesyl pyrophosphate synthase, putative | 0.0329 | 0.3753 | 0.5816 |
Trypanosoma cruzi | heat shock protein 85, putative | 0.0029 | 0.0135 | 0.0142 |
Leishmania major | vacuolar-type proton translocating pyrophosphatase 1, putative | 0.0325 | 0.3708 | 0.5683 |
Echinococcus granulosus | Alpha N acetylgalactosaminidase | 0.0115 | 0.1169 | 0.1233 |
Leishmania major | solanesyl-diphosphate synthase, putative | 0.0174 | 0.1888 | 0.2789 |
Echinococcus multilocularis | decaprenyl diphosphate synthase subunit 1 | 0.0174 | 0.1888 | 0.1888 |
Loa Loa (eye worm) | mbt repeat family protein | 0.005 | 0.0386 | 0.059 |
Plasmodium falciparum | V-type H(+)-translocating pyrophosphatase, putative | 0.0325 | 0.3708 | 0.9878 |
Brugia malayi | Endoplasmin precursor | 0.0036 | 0.0224 | 0.0298 |
Treponema pallidum | hexokinase (hxk) | 0.0082 | 0.0777 | 0.1022 |
Echinococcus granulosus | microtubule associated protein 2 | 0.0804 | 0.9482 | 1 |
Echinococcus multilocularis | inositol monophosphatase 1 | 0.0043 | 0.0304 | 0.0304 |
Echinococcus multilocularis | polycomb protein SCMH1 | 0.005 | 0.0386 | 0.0386 |
Echinococcus granulosus | polycomb protein SCMH1 | 0.005 | 0.0386 | 0.0407 |
Echinococcus multilocularis | hexokinase | 0.0082 | 0.0777 | 0.0777 |
Echinococcus granulosus | lipoxygenase domain containing protein | 0.0021 | 0.0034 | 0.0035 |
Mycobacterium leprae | PROBABLE POLYPRENYL-DIPHOSPHATE SYNTHASE GRCC1 (POLYPRENYL PYROPHOSPHATE SYNTHETASE) | 0.0174 | 0.1888 | 1 |
Wolbachia endosymbiont of Brugia malayi | geranylgeranyl pyrophosphate synthase | 0.0174 | 0.1888 | 1 |
Activity type | Activity value | Assay description | Source | Reference |
---|---|---|---|---|
Activity (functional) | 0 | Anti HIV-1 activity of the compound was evaluated through C8166/GUN1WT syncytium formation assay at a concentration of 0 ug/mL; NT=Not tested | ChEMBL. | 11551760 |
Activity (functional) | = 1 | Anti HIV-1 activity of the compound was evaluated through C8166/GUN1WT syncytium formation assay at a concentration of 1000 ug/mL | ChEMBL. | 11551760 |
Activity (functional) | = 66 | Anti HIV-1 activity of the compound was evaluated through C8166/GUN1WT syncytium formation assay at a concentration of 200 ug/mL | ChEMBL. | 11551760 |
Activity (functional) | = 219 | Anti HIV-1 activity of the compound was evaluated through C8166/GUN1WT syncytium formation assay at a concentration of 50 ug/mL | ChEMBL. | 11551760 |
IC50 (functional) | = 4.1 uM | Anti HIV-1 activity of the compound measured in terms of cytotoxicity against NP-2/CD4/GPR1 cells infected with HIV-1 (GUN1V) | ChEMBL. | 11551760 |
IC50 (functional) | = 10 uM | Anti HIV-1 activity of the compound measured in terms of cytotoxicity against NP-2/CD4/CXCR4 cells infected with HIV-1 (IIIBstrain) | ChEMBL. | 11551760 |
IC50 (functional) | = 10 uM | Anti HIV-1 activity of the compound measured in terms of cytotoxicity against NP-2/CD4/CXCR4 cells infected with HIV-1(GUN1WT) | ChEMBL. | 11551760 |
IC50 (functional) | = 42 uM | Anti HIV-1 activity of the compound measured in terms of cytotoxicity against NP-2/CD4/CCR5 cells infected with HIV-1(GUN1WT) | ChEMBL. | 11551760 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.
1 literature reference was collected for this gene.