Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Leishmania major | cathepsin L-like protease | 0.1319 | 1 | 1 |
Plasmodium vivax | serine-repeat antigen 3 (SERA) | 0.0243 | 0.1737 | 0.173 |
Brugia malayi | Cathepsin L-like precursor | 0.1319 | 1 | 1 |
Brugia malayi | cathepsin L-like cysteine proteinase | 0.0243 | 0.1737 | 0.173 |
Schistosoma mansoni | hypothetical protein | 0.0172 | 0.1189 | 0.1189 |
Loa Loa (eye worm) | hypothetical protein | 0.0436 | 0.3217 | 0.3217 |
Giardia lamblia | Cysteine protease | 0.0243 | 0.1737 | 1 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.1319 | 1 | 1 |
Toxoplasma gondii | cathepsin CPC2 | 0.0243 | 0.1737 | 0.173 |
Trypanosoma cruzi | cysteine peptidase, putative | 0.1319 | 1 | 1 |
Echinococcus granulosus | cathepsin l1 | 0.0883 | 0.665 | 0.665 |
Plasmodium vivax | vivapain-2 | 0.1319 | 1 | 1 |
Entamoeba histolytica | cysteine protease, putative | 0.068 | 0.5087 | 0.5083 |
Schistosoma mansoni | acetyl-CoA C-acetyltransferase | 0.0023 | 0.0043 | 0.0043 |
Plasmodium falciparum | dipeptidyl aminopeptidase 1 | 0.0243 | 0.1737 | 0.173 |
Leishmania major | cysteine peptidase A (CPA) | 0.1319 | 1 | 1 |
Schistosoma mansoni | cathepsin C | 0.0243 | 0.1737 | 0.1737 |
Echinococcus granulosus | cysteine protease | 0.068 | 0.5087 | 0.5087 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin H-like cysteine peptidase | 0.0243 | 0.1737 | 0.173 |
Echinococcus multilocularis | DNA (apurinic or apyrimidinic site) lyase | 0.0018 | 0.0008 | 0.0008 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin F-like cysteine peptidase | 0.0243 | 0.1737 | 0.173 |
Echinococcus multilocularis | fetal alzheimer antigen, falz | 0.0023 | 0.0043 | 0.0043 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.1319 | 1 | 1 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.1319 | 1 | 1 |
Toxoplasma gondii | cathepsin CPC1 | 0.0243 | 0.1737 | 0.173 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0243 | 0.1737 | 0.173 |
Schistosoma mansoni | cathepsin F (C01 family) | 0.1319 | 1 | 1 |
Entamoeba histolytica | cysteine protease, putative | 0.068 | 0.5087 | 0.5083 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.1319 | 1 | 1 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.1319 | 1 | 1 |
Schistosoma mansoni | cathepsin B-like peptidase (C01 family) | 0.0243 | 0.1737 | 0.1737 |
Brugia malayi | cathepsin L-like cysteine proteinase, identical | 0.0436 | 0.3217 | 0.3212 |
Schistosoma mansoni | cathepsin B-like peptidase (C01 family) | 0.0243 | 0.1737 | 0.1737 |
Trypanosoma cruzi | cysteine proteinase, putative | 0.068 | 0.5087 | 0.5083 |
Trypanosoma cruzi | cysteine peptidase, putative | 0.1319 | 1 | 1 |
Plasmodium falciparum | serine repeat antigen 2 | 0.0243 | 0.1737 | 0.173 |
Plasmodium vivax | serine-repeat antigen (SERA), putative | 0.0243 | 0.1737 | 0.173 |
Entamoeba histolytica | myo-inositol monophosphatase, putative | 0.0036 | 0.0144 | 0.0136 |
Schistosoma mansoni | ap endonuclease | 0.0018 | 0.0008 | 0.0008 |
Onchocerca volvulus | 0.1319 | 1 | 1 | |
Plasmodium vivax | vivapain-2 | 0.1319 | 1 | 1 |
Giardia lamblia | Hypothetical protein | 0.0243 | 0.1737 | 1 |
Plasmodium vivax | serine-repeat antigen 5 (SERA) | 0.0243 | 0.1737 | 0.173 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.1319 | 1 | 1 |
Giardia lamblia | Cathepsin B-like cysteine proteinase 3 precursor | 0.0243 | 0.1737 | 1 |
Entamoeba histolytica | papain family cysteine protease domain containing protein | 0.0243 | 0.1737 | 0.173 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L or K-like cysteine peptidase | 0.1319 | 1 | 1 |
Entamoeba histolytica | cysteine proteinase, putative | 0.1319 | 1 | 1 |
Entamoeba histolytica | cysteine proteinase, putative | 0.068 | 0.5087 | 0.5083 |
Leishmania major | cathepsin L-like protease | 0.1319 | 1 | 1 |
Schistosoma mansoni | cathepsin B-like peptidase (C01 family) | 0.0243 | 0.1737 | 0.1737 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.1319 | 1 | 1 |
Brugia malayi | Cathepsin L-like precursor | 0.1319 | 1 | 1 |
Entamoeba histolytica | cysteine proteinase, putative | 0.1319 | 1 | 1 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.1319 | 1 | 1 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.1319 | 1 | 1 |
Onchocerca volvulus | 0.1319 | 1 | 1 | |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.1319 | 1 | 1 |
Echinococcus granulosus | zinc finger protein | 0.002 | 0.002 | 0.002 |
Entamoeba histolytica | cysteine proteinase, putative | 0.068 | 0.5087 | 0.5083 |
Schistosoma mansoni | ap endonuclease | 0.0018 | 0.0008 | 0.0008 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.1319 | 1 | 1 |
Trypanosoma cruzi | major cysteine proteinase, putative | 0.0243 | 0.1737 | 0.173 |
Mycobacterium tuberculosis | Inositol-1-monophosphatase SuhB | 0.0032 | 0.0115 | 1 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.1319 | 1 | 1 |
Giardia lamblia | Cathepsin B precursor | 0.0243 | 0.1737 | 1 |
Leishmania major | cysteine peptidase C (CPC),CPC cysteine peptidase, Clan CA, family C1, Cathepsin B-like | 0.0243 | 0.1737 | 0.173 |
Trypanosoma cruzi | cysteine peptidase C (CPC), putative | 0.0243 | 0.1737 | 0.173 |
Echinococcus multilocularis | cathepsin b | 0.0243 | 0.1737 | 0.1737 |
Onchocerca volvulus | Cathepsin L homolog | 0.1319 | 1 | 1 |
Trypanosoma cruzi | cruzipain precursor, putative | 0.0436 | 0.3217 | 0.3212 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.1319 | 1 | 1 |
Giardia lamblia | Cathepsin L precursor | 0.0243 | 0.1737 | 1 |
Wolbachia endosymbiont of Brugia malayi | fructose-1,6-bisphosphatase | 0.0036 | 0.0144 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0243 | 0.1737 | 0.1737 |
Loa Loa (eye worm) | hypothetical protein | 0.0039 | 0.0166 | 0.0166 |
Echinococcus granulosus | DNA apurinic or apyrimidinic site lyase | 0.0018 | 0.0008 | 0.0008 |
Leishmania major | cathepsin L-like protease | 0.1319 | 1 | 1 |
Leishmania major | cathepsin L-like protease | 0.1319 | 1 | 1 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L or K-like cysteine peptidase | 0.1319 | 1 | 1 |
Schistosoma mansoni | subfamily C1A unassigned peptidase (C01 family) | 0.0243 | 0.1737 | 0.1737 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.068 | 0.5087 | 0.5083 |
Onchocerca volvulus | 0.1319 | 1 | 1 | |
Schistosoma mansoni | inositol monophosphatase | 0.0036 | 0.0144 | 0.0144 |
Onchocerca volvulus | 0.1319 | 1 | 1 | |
Schistosoma mansoni | cathepsin B-like peptidase (C01 family) | 0.0243 | 0.1737 | 0.1737 |
Schistosoma mansoni | bromodomain containing protein | 0.0064 | 0.0361 | 0.0361 |
Mycobacterium ulcerans | extragenic suppressor protein SuhB | 0.0036 | 0.0144 | 1 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.1319 | 1 | 1 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0243 | 0.1737 | 0.173 |
Brugia malayi | cahepsin L-like non-peptiedase homolog | 0.0243 | 0.1737 | 0.173 |
Brugia malayi | PHD-finger family protein | 0.0025 | 0.0061 | 0.0053 |
Plasmodium vivax | dipeptidyl aminopeptidase 3, putative | 0.0243 | 0.1737 | 0.173 |
Brugia malayi | Papain family cysteine protease containing protein | 0.068 | 0.5087 | 0.5083 |
Loa Loa (eye worm) | exodeoxyribonuclease III family protein | 0.0018 | 0.0008 | 0.0008 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.0243 | 0.1737 | 0.173 |
Echinococcus multilocularis | atpase aaa+ type core atpase aaa type core | 0.0791 | 0.5941 | 0.5941 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.068 | 0.5087 | 0.5083 |
Echinococcus granulosus | cathepsin L | 0.0243 | 0.1737 | 0.1737 |
Plasmodium falciparum | cysteine proteinase falcipain 1 | 0.068 | 0.5087 | 0.5083 |
Plasmodium vivax | dipeptidyl aminopeptidase 2, putative | 0.0243 | 0.1737 | 0.173 |
Schistosoma mansoni | SmCB2 peptidase (C01 family) | 0.0243 | 0.1737 | 0.1737 |
Plasmodium vivax | unspecified product | 0.0243 | 0.1737 | 0.173 |
Loa Loa (eye worm) | ctsf protein | 0.1319 | 1 | 1 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.1319 | 1 | 1 |
Trypanosoma cruzi | cysteine peptidase, putative | 0.0436 | 0.3217 | 0.3212 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0243 | 0.1737 | 0.173 |
Loa Loa (eye worm) | hypothetical protein | 0.0043 | 0.02 | 0.02 |
Echinococcus multilocularis | cathepsin L cysteine protease | 0.1319 | 1 | 1 |
Giardia lamblia | Dipeptidyl-peptidase I precursor | 0.0243 | 0.1737 | 1 |
Entamoeba histolytica | cysteine protease, putative | 0.0243 | 0.1737 | 0.173 |
Loa Loa (eye worm) | papain family cysteine protease containing protein | 0.0243 | 0.1737 | 0.1737 |
Brugia malayi | cathepsin F-like cysteine proteinase | 0.0243 | 0.1737 | 0.173 |
Loa Loa (eye worm) | papain family cysteine protease containing protein | 0.1319 | 1 | 1 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0243 | 0.1737 | 0.173 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.1319 | 1 | 1 |
Trypanosoma cruzi | cysteine proteinase, putative | 0.068 | 0.5087 | 0.5083 |
Loa Loa (eye worm) | hypothetical protein | 0.0436 | 0.3217 | 0.3217 |
Plasmodium falciparum | cysteine proteinase falcipain 2a | 0.1319 | 1 | 1 |
Trypanosoma cruzi | cysteine peptidase (N-terminal), putative | 0.068 | 0.5087 | 0.5083 |
Brugia malayi | Cathepsin L-like precursor | 0.0883 | 0.665 | 0.6647 |
Giardia lamblia | Cathepsin L precursor | 0.0243 | 0.1737 | 1 |
Entamoeba histolytica | cysteine protease, putative | 0.0243 | 0.1737 | 0.173 |
Entamoeba histolytica | cysteine proteinase, putative | 0.0883 | 0.665 | 0.6647 |
Giardia lamblia | Cathepsin B precursor | 0.0243 | 0.1737 | 1 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0883 | 0.665 | 0.6647 |
Brugia malayi | Cathepsin L-like precursor | 0.1319 | 1 | 1 |
Entamoeba histolytica | cysteine protease, putative | 0.0243 | 0.1737 | 0.173 |
Trypanosoma cruzi | major cysteine proteinase, putative | 0.0243 | 0.1737 | 0.173 |
Giardia lamblia | Cathepsin B precursor | 0.0243 | 0.1737 | 1 |
Schistosoma mansoni | zinc finger protein | 0.002 | 0.002 | 0.002 |
Brugia malayi | Papain family cysteine protease containing protein | 0.1319 | 1 | 1 |
Plasmodium vivax | serine-repeat antigen (SERA) | 0.0243 | 0.1737 | 0.173 |
Entamoeba histolytica | cysteine protease, putative | 0.0243 | 0.1737 | 0.173 |
Leishmania major | cathepsin L-like protease | 0.1319 | 1 | 1 |
Trypanosoma cruzi | cysteine peptidase, putative | 0.1319 | 1 | 1 |
Echinococcus granulosus | bromodomain adjacent to zinc finger domain | 0.0061 | 0.0333 | 0.0333 |
Giardia lamblia | Cathepsin L precursor | 0.0243 | 0.1737 | 1 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.1319 | 1 | 1 |
Echinococcus multilocularis | inositol monophosphatase 1 | 0.0036 | 0.0144 | 0.0144 |
Giardia lamblia | Cysteine protease | 0.0243 | 0.1737 | 1 |
Onchocerca volvulus | 0.1319 | 1 | 1 | |
Brugia malayi | Cathepsin L-like precursor | 0.0883 | 0.665 | 0.6647 |
Trypanosoma cruzi | cysteine peptidase, clan CA, family C1, cathepsin L-like, putative | 0.0883 | 0.665 | 0.6647 |
Brugia malayi | Papain family cysteine protease containing protein | 0.0243 | 0.1737 | 0.173 |
Trypanosoma cruzi | cruzipain precursor, putative | 0.1319 | 1 | 1 |
Leishmania major | cathepsin L-like protease | 0.1319 | 1 | 1 |
Entamoeba histolytica | cysteine proteinase 2 | 0.068 | 0.5087 | 0.5083 |
Loa Loa (eye worm) | hypothetical protein | 0.0243 | 0.1737 | 0.1737 |
Onchocerca volvulus | 0.1319 | 1 | 1 | |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.1319 | 1 | 1 |
Giardia lamblia | Encystation-specific protease | 0.0243 | 0.1737 | 1 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0243 | 0.1737 | 0.173 |
Schistosoma mansoni | inositol monophosphatase | 0.0036 | 0.0144 | 0.0144 |
Giardia lamblia | Cathepsin B precursor | 0.0243 | 0.1737 | 1 |
Brugia malayi | Bromodomain containing protein | 0.0039 | 0.0166 | 0.0158 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin B-like cysteine peptidase | 0.0243 | 0.1737 | 0.173 |
Trichomonas vaginalis | myo inositol monophosphatase, putative | 0.0036 | 0.0144 | 0.0136 |
Echinococcus multilocularis | cathepsin L | 0.068 | 0.5087 | 0.5087 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.1319 | 1 | 1 |
Echinococcus multilocularis | bromodomain adjacent to zinc finger domain | 0.0036 | 0.0147 | 0.0147 |
Giardia lamblia | Cysteine protease | 0.0243 | 0.1737 | 1 |
Mycobacterium leprae | possible inositol monophosphatase SubH (IMPase) (inositol-1-phosphatase) (I-1-Pase ). | 0.0032 | 0.0115 | 0.5 |
Entamoeba histolytica | cysteine protease, putative | 0.068 | 0.5087 | 0.5083 |
Trypanosoma cruzi | cysteine peptidase C (CPC), putative | 0.0243 | 0.1737 | 0.173 |
Trypanosoma cruzi | cysteine peptidase, putative | 0.068 | 0.5087 | 0.5083 |
Echinococcus granulosus | fetal alzheimer antigen falz | 0.0023 | 0.0043 | 0.0043 |
Trypanosoma brucei | inositol-1(or 4)-monophosphatase 1, putative | 0.0036 | 0.0144 | 0.0136 |
Echinococcus multilocularis | cysteine protease | 0.1319 | 1 | 1 |
Brugia malayi | Inositol-1 | 0.0036 | 0.0144 | 0.0136 |
Entamoeba histolytica | cysteine protease, putative | 0.068 | 0.5087 | 0.5083 |
Brugia malayi | cathepsin F-like cysteine proteinase | 0.0436 | 0.3217 | 0.3212 |
Toxoplasma gondii | cathepsin B | 0.0243 | 0.1737 | 0.173 |
Giardia lamblia | Cathepsin L-like protease | 0.0243 | 0.1737 | 1 |
Plasmodium vivax | unspecified product | 0.0436 | 0.3217 | 0.3212 |
Loa Loa (eye worm) | bromodomain containing protein | 0.0018 | 0.0005 | 0.0005 |
Echinococcus granulosus | bromodomain adjacent to zinc finger domain | 0.0036 | 0.0147 | 0.0147 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.1319 | 1 | 1 |
Schistosoma mansoni | subfamily C1A non-peptidase homologue (C01 family) | 0.0243 | 0.1737 | 0.1737 |
Loa Loa (eye worm) | hypothetical protein | 0.0243 | 0.1737 | 0.1737 |
Entamoeba histolytica | hypothetical protein | 0.0243 | 0.1737 | 0.173 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.1319 | 1 | 1 |
Schistosoma mansoni | subfamily C1A unassigned peptidase (C01 family) | 0.0243 | 0.1737 | 0.1737 |
Giardia lamblia | Cathepsin B precursor | 0.0243 | 0.1737 | 1 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin B-like cysteine peptidase | 0.0243 | 0.1737 | 0.173 |
Plasmodium vivax | unspecified product | 0.068 | 0.5087 | 0.5083 |
Entamoeba histolytica | cysteine protease, putative | 0.068 | 0.5087 | 0.5083 |
Giardia lamblia | Cathepsin L precursor | 0.0243 | 0.1737 | 1 |
Entamoeba histolytica | cysteine protease, putative | 0.0243 | 0.1737 | 0.173 |
Loa Loa (eye worm) | hypothetical protein | 0.0883 | 0.665 | 0.665 |
Schistosoma mansoni | cathepsin B-like peptidase (C01 family) | 0.0243 | 0.1737 | 0.1737 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.1319 | 1 | 1 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.1319 | 1 | 1 |
Plasmodium falciparum | serine repeat antigen 1 | 0.0243 | 0.1737 | 0.173 |
Brugia malayi | Bromodomain containing protein | 0.0076 | 0.0452 | 0.0445 |
Loa Loa (eye worm) | hypothetical protein | 0.0243 | 0.1737 | 0.1737 |
Loa Loa (eye worm) | hypothetical protein | 0.0243 | 0.1737 | 0.1737 |
Plasmodium falciparum | serine repeat antigen 6 | 0.0243 | 0.1737 | 0.173 |
Trichomonas vaginalis | inositol monophosphatase, putative | 0.0036 | 0.0144 | 0.0136 |
Trypanosoma cruzi | myo-inositol-1(or 4)-monophosphatase 1, putative | 0.0036 | 0.0144 | 0.0136 |
Echinococcus multilocularis | cathepsin b | 0.0243 | 0.1737 | 0.1737 |
Plasmodium falciparum | serine repeat antigen 3 | 0.0243 | 0.1737 | 0.173 |
Entamoeba histolytica | cysteine protease, putative | 0.068 | 0.5087 | 0.5083 |
Trypanosoma cruzi | cysteine peptidase, putative | 0.1319 | 1 | 1 |
Brugia malayi | Cathepsin L-like precursor | 0.0436 | 0.3217 | 0.3212 |
Brugia malayi | Papain family cysteine protease containing protein | 0.068 | 0.5087 | 0.5083 |
Entamoeba histolytica | cysteine protease, putative | 0.0243 | 0.1737 | 0.173 |
Giardia lamblia | Cathepsin B precursor | 0.0243 | 0.1737 | 1 |
Entamoeba histolytica | cysteine protease, putative | 0.1319 | 1 | 1 |
Loa Loa (eye worm) | PHD-finger family protein | 0.0021 | 0.0028 | 0.0028 |
Loa Loa (eye worm) | cathepsin B | 0.0243 | 0.1737 | 0.1737 |
Giardia lamblia | Cathepsin L precursor | 0.0243 | 0.1737 | 1 |
Entamoeba histolytica | cysteine protease, putative | 0.068 | 0.5087 | 0.5083 |
Entamoeba histolytica | cysteine proteinase, putative | 0.068 | 0.5087 | 0.5083 |
Schistosoma mansoni | dipeptidyl-peptidase I (C01 family) | 0.0243 | 0.1737 | 0.1737 |
Entamoeba histolytica | cysteine protease, putative | 0.068 | 0.5087 | 0.5083 |
Entamoeba histolytica | cysteine protease, putative | 0.068 | 0.5087 | 0.5083 |
Plasmodium vivax | serine-repeat antigen (SERA) | 0.0243 | 0.1737 | 0.173 |
Plasmodium vivax | vivapain-3 | 0.068 | 0.5087 | 0.5083 |
Schistosoma mansoni | cathepsin B-like peptidase (C01 family) | 0.0243 | 0.1737 | 0.1737 |
Loa Loa (eye worm) | fibroinase | 0.1319 | 1 | 1 |
Echinococcus multilocularis | cathepsin l cysteine peptidase | 0.1319 | 1 | 1 |
Loa Loa (eye worm) | papain family cysteine protease containing protein | 0.0436 | 0.3217 | 0.3217 |
Giardia lamblia | Cysteine protease | 0.0243 | 0.1737 | 1 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.1319 | 1 | 1 |
Plasmodium falciparum | serine repeat antigen 7 | 0.0243 | 0.1737 | 0.173 |
Trypanosoma cruzi | myo-inositol-1(or 4)-monophosphatase 1, putative | 0.0036 | 0.0144 | 0.0136 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.1319 | 1 | 1 |
Brugia malayi | cathepsin Z-like cysteine proteinase | 0.0243 | 0.1737 | 0.173 |
Giardia lamblia | Cathepsin B precursor | 0.0243 | 0.1737 | 1 |
Onchocerca volvulus | 0.1319 | 1 | 1 | |
Echinococcus granulosus | cathepsin b | 0.0243 | 0.1737 | 0.1737 |
Schistosoma mansoni | cathepsin B (C01 family) | 0.0243 | 0.1737 | 0.1737 |
Loa Loa (eye worm) | hypothetical protein | 0.0436 | 0.3217 | 0.3217 |
Brugia malayi | Cathepsin L-like precursor | 0.1319 | 1 | 1 |
Plasmodium vivax | vivapain-1 | 0.068 | 0.5087 | 0.5083 |
Entamoeba histolytica | cysteine proteinase 1, putative | 0.068 | 0.5087 | 0.5083 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.1319 | 1 | 1 |
Loa Loa (eye worm) | papain family cysteine protease containing protein | 0.0243 | 0.1737 | 0.1737 |
Plasmodium falciparum | serine repeat antigen 5 | 0.0243 | 0.1737 | 0.173 |
Schistosoma mansoni | cathepsin B-like peptidase (C01 family) | 0.0243 | 0.1737 | 0.1737 |
Brugia malayi | cathepsin B-like cysteine proteinase | 0.0243 | 0.1737 | 0.173 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L or H-like cysteine peptidase | 0.0243 | 0.1737 | 0.173 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.1319 | 1 | 1 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.1319 | 1 | 1 |
Toxoplasma gondii | cathepsin CPL | 0.1319 | 1 | 1 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0243 | 0.1737 | 0.173 |
Loa Loa (eye worm) | cysteine protease | 0.1319 | 1 | 1 |
Echinococcus granulosus | cathepsin L cysteine proteinase | 0.1319 | 1 | 1 |
Giardia lamblia | Cathepsin L-like protease | 0.0243 | 0.1737 | 1 |
Schistosoma mansoni | cathepsin s | 0.0436 | 0.3217 | 0.3217 |
Brugia malayi | Papain family cysteine protease containing protein | 0.0243 | 0.1737 | 0.173 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0243 | 0.1737 | 0.173 |
Leishmania major | myo-inositol-1(or 4)-monophosphatase 1, putative | 0.0036 | 0.0144 | 0.0136 |
Echinococcus granulosus | geminin | 0.0172 | 0.1189 | 0.1189 |
Plasmodium falciparum | cysteine proteinase falcipain 3 | 0.1319 | 1 | 1 |
Entamoeba histolytica | cysteine proteinase, putative | 0.068 | 0.5087 | 0.5083 |
Echinococcus multilocularis | geminin | 0.0172 | 0.1189 | 0.1189 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.1319 | 1 | 1 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.1319 | 1 | 1 |
Schistosoma mansoni | hypothetical protein | 0.0172 | 0.1189 | 0.1189 |
Echinococcus multilocularis | bromodomain adjacent to zinc finger domain | 0.0061 | 0.0333 | 0.0333 |
Brugia malayi | Cathepsin L-like cysteine proteinase | 0.0883 | 0.665 | 0.6647 |
Plasmodium vivax | serine-repeat antigen 4 (SERA) | 0.0243 | 0.1737 | 0.173 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0243 | 0.1737 | 0.173 |
Loa Loa (eye worm) | hypothetical protein | 0.0243 | 0.1737 | 0.1737 |
Giardia lamblia | Cathepsin B precursor | 0.0243 | 0.1737 | 1 |
Plasmodium falciparum | serine repeat antigen 9 | 0.0243 | 0.1737 | 0.173 |
Loa Loa (eye worm) | hypothetical protein | 0.0243 | 0.1737 | 0.1737 |
Brugia malayi | Papain family cysteine protease containing protein | 0.0243 | 0.1737 | 0.173 |
Plasmodium falciparum | serine repeat antigen 4 | 0.0243 | 0.1737 | 0.173 |
Entamoeba histolytica | cysteine protease, putative | 0.068 | 0.5087 | 0.5083 |
Giardia lamblia | Dipeptidyl-peptidase I precursor | 0.0243 | 0.1737 | 1 |
Schistosoma mansoni | SmCL2-like peptidase (C01 family) | 0.068 | 0.5087 | 0.5087 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L, S or H-like cysteine peptidase | 0.0243 | 0.1737 | 0.173 |
Loa Loa (eye worm) | hypothetical protein | 0.0883 | 0.665 | 0.665 |
Brugia malayi | cathepsin Z-like cysteine proteinase | 0.0243 | 0.1737 | 0.173 |
Brugia malayi | cathepsin L-like precursor | 0.0883 | 0.665 | 0.6647 |
Plasmodium vivax | serine-repeat antigen 4 (SERA), putative | 0.0243 | 0.1737 | 0.173 |
Schistosoma mansoni | SmCL2-like peptidase (C01 family) | 0.068 | 0.5087 | 0.5087 |
Toxoplasma gondii | inositol(myo)-1(or 4)-monophosphatase 2, putative | 0.0036 | 0.0144 | 0.0136 |
Plasmodium falciparum | dipeptidyl aminopeptidase 3 | 0.0243 | 0.1737 | 0.173 |
Plasmodium falciparum | serine repeat antigen 8 | 0.0243 | 0.1737 | 0.173 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.1319 | 1 | 1 |
Leishmania major | cathepsin L-like protease | 0.1319 | 1 | 1 |
Schistosoma mansoni | SmCL2-like peptidase (C01 family) | 0.068 | 0.5087 | 0.5087 |
Echinococcus multilocularis | cathepsin l cysteine peptidase | 0.1319 | 1 | 1 |
Plasmodium vivax | serine-repeat antigen 2 (SERA) | 0.0243 | 0.1737 | 0.173 |
Echinococcus multilocularis | cathepsin L cysteine protease | 0.1319 | 1 | 1 |
Trypanosoma cruzi | cysteine protease, putative | 0.068 | 0.5087 | 0.5083 |
Brugia malayi | Cathepsin L-like precursor | 0.1319 | 1 | 1 |
Leishmania major | cathepsin L-like protease | 0.1319 | 1 | 1 |
Echinococcus granulosus | cathepsin L | 0.068 | 0.5087 | 0.5087 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.0243 | 0.1737 | 0.173 |
Trichomonas vaginalis | myo inositol monophosphatase, putative | 0.0036 | 0.0144 | 0.0136 |
Entamoeba histolytica | cysteine protease, putative | 0.068 | 0.5087 | 0.5083 |
Echinococcus granulosus | cathepsin l cysteine peptidase | 0.1319 | 1 | 1 |
Brugia malayi | fibroinase precursor | 0.0243 | 0.1737 | 0.173 |
Entamoeba histolytica | papain family cysteine protease domain containing protein | 0.0243 | 0.1737 | 0.173 |
Echinococcus multilocularis | zinc finger protein | 0.002 | 0.002 | 0.002 |
Schistosoma mansoni | cathepsin S (C01 family) | 0.0243 | 0.1737 | 0.1737 |
Onchocerca volvulus | Cathepsin L homolog | 0.1319 | 1 | 1 |
Onchocerca volvulus | 0.0883 | 0.665 | 0.5946 | |
Giardia lamblia | Cathepsin L precursor | 0.0243 | 0.1737 | 1 |
Plasmodium falciparum | dipeptidyl aminopeptidase 2 | 0.0243 | 0.1737 | 0.173 |
Giardia lamblia | Hypothetical protein | 0.0243 | 0.1737 | 1 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.0243 | 0.1737 | 0.173 |
Echinococcus granulosus | inositol monophosphatase 1 | 0.0036 | 0.0144 | 0.0144 |
Loa Loa (eye worm) | inositol-1 | 0.0036 | 0.0144 | 0.0144 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0883 | 0.665 | 0.6647 |
Onchocerca volvulus | Cathepsin F homolog | 0.1319 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0883 | 0.665 | 0.665 |
Brugia malayi | cathepsin L precursor | 0.0243 | 0.1737 | 0.173 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin B-like cysteine peptidase | 0.0243 | 0.1737 | 0.173 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.068 | 0.5087 | 0.5083 |
Toxoplasma gondii | preprocathepsin c precursor, putative | 0.0243 | 0.1737 | 0.173 |
Echinococcus multilocularis | cysteine protease | 0.1319 | 1 | 1 |
Schistosoma mansoni | cathepsin B-like peptidase (C01 family) | 0.0243 | 0.1737 | 0.1737 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.1319 | 1 | 1 |
Schistosoma mansoni | cathepsin B-like peptidase (C01 family) | 0.0243 | 0.1737 | 0.1737 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin B-like cysteine peptidase | 0.0243 | 0.1737 | 0.173 |
Loa Loa (eye worm) | hypothetical protein | 0.0041 | 0.0185 | 0.0185 |
Schistosoma mansoni | cathepsin F (C01 family) | 0.1319 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0072 | 0.0419 | 0.0419 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.068 | 0.5087 | 0.5083 |
Treponema pallidum | exodeoxyribonuclease (exoA) | 0.0018 | 0.0008 | 0.5 |
Plasmodium vivax | dipeptidyl aminopeptidase 1, putative | 0.0243 | 0.1737 | 0.173 |
Trypanosoma brucei | cysteine peptidase C (CPC) | 0.0243 | 0.1737 | 0.173 |
Echinococcus granulosus | cathepsin l1 | 0.1319 | 1 | 1 |
Schistosoma mansoni | cathepsin F (C01 family) | 0.0883 | 0.665 | 0.665 |
Echinococcus granulosus | cathepsin b | 0.0243 | 0.1737 | 0.1737 |
Schistosoma mansoni | hypothetical protein | 0.0021 | 0.0028 | 0.0028 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.1319 | 1 | 1 |
Loa Loa (eye worm) | Papain cysteine protease/cathepsin propeptide inhibitor-containing protein | 0.1319 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.1319 | 1 | 1 |
Echinococcus granulosus | cathepsin L cysteine protease | 0.068 | 0.5087 | 0.5087 |
Plasmodium falciparum | cysteine proteinase falcipain 2b | 0.1319 | 1 | 1 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin B-like cysteine peptidase | 0.0243 | 0.1737 | 0.173 |
Entamoeba histolytica | cysteine protease, putative | 0.068 | 0.5087 | 0.5083 |
Entamoeba histolytica | cysteine protease, putative | 0.068 | 0.5087 | 0.5083 |
Plasmodium vivax | serine-repeat antigen (SERA), putative | 0.0243 | 0.1737 | 0.173 |
Giardia lamblia | Dipeptidyl-peptidase I precursor | 0.0243 | 0.1737 | 1 |
Echinococcus multilocularis | cathepsin L | 0.0243 | 0.1737 | 0.1737 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.1319 | 1 | 1 |
Loa Loa (eye worm) | cysteine proteinase cathepsin Z | 0.0243 | 0.1737 | 0.1737 |
Activity type | Activity value | Assay description | Source | Reference |
---|---|---|---|---|
Duration of action (functional) | = 24 hr | Duration of action, measured using castrated male rat assay to inhibit luteinizing hormone release.; fully active at 24 hr but not at 48 hr | ChEMBL. | 7629804 |
Duration of action (functional) | = 24 hr | Duration of action, measured using castrated male rat assay to inhibit luteinizing hormone release.; fully active at 24 hr but not at 48 hr | ChEMBL. | 7629804 |
No. of rats ovulated (functional) | = 0 | Effect of the compound in the anti ovulatory assay (AOA) in rats expressed as no. of rats ovulating/No of rats treated at 2.5 mg; 0/2 | ChEMBL. | 7629804 |
No. of rats ovulated (functional) | = 4 | Effect of the compound in the anti ovulatory assay (AOA) in rats expressed as no. of rats ovulating/No of rats treated at 1.0 mg; 4/15 | ChEMBL. | 7629804 |
No. of rats ovulated (functional) | = 8 | Effect of the compound in the anti ovulatory assay (AOA) in rats expressed as no. of rats ovulating/No of rats treated at 0.5 mg; 8/8 | ChEMBL. | 7629804 |
Relative potency (functional) | = 0.47 | In vitro potency to inhibit GnRH-mediated LH secretion by cultured pituitary cells relative to [Ac-deltaPro1,DFpa2,DTrp36]GnRH. | ChEMBL. | 7629804 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.
1 literature reference was collected for this gene.