Detailed information for compound 401152

Basic information

Technical information
  • Name: Unnamed compound
  • MW: 978.106 | Formula: C49H63N13O9
  • H donors: 12 H acceptors: 9 LogP: 0.48 Rotable bonds: 18
    Rule of 5 violations (Lipinski): 3
  • SMILES: CCCC[C@@H](C(=O)N[C@@H]1CC(=O)NC[C@H](NC(=O)[C@@H](NC(=O)[C@H](NC(=O)[C@@H](NC(=O)[C@H](NC1=O)Cc1ccccc1)Cc1ccccc1)CCCN=C(N)N)c1c[nH]c2c1cccc2)C(=O)N)NC(=O)C
  • InChi: 1S/C49H63N13O9/c1-3-4-19-34(56-28(2)63)43(66)60-38-25-40(64)55-27-39(42(50)65)61-48(71)41(32-26-54-33-20-12-11-18-31(32)33)62-44(67)35(21-13-22-53-49(51)52)57-45(68)36(23-29-14-7-5-8-15-29)58-46(69)37(59-47(38)70)24-30-16-9-6-10-17-30/h5-12,14-18,20,26,34-39,41,54H,3-4,13,19,21-25,27H2,1-2H3,(H2,50,65)(H,55,64)(H,56,63)(H,57,68)(H,58,69)(H,59,70)(H,60,66)(H,61,71)(H,62,67)(H4,51,52,53)/t34-,35+,36-,37+,38+,39-,41-/m0/s1
  • InChiKey: JFYGAKDZFHZADN-QJVHMFQFSA-N  


Substructure search Similarity search

Network

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Synonyms

No synonyms found for this compound

Targets

Known targets for this compound

No curated genes were found associated with this compound

Predicted pathogen targets for this compound

By orthology
No druggable targets predicted by orthology data
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Loa Loa (eye worm) nuclear hormone receptor family member nhr-41 0.0014 0.0038 0.0067
Echinococcus multilocularis protein dispatched 1 0.0024 0.0303 0.0266
Echinococcus granulosus Niemann Pick C1 protein 0.0049 0.0942 0.109
Loa Loa (eye worm) nuclear hormone receptor family member nhr-40 0.0014 0.0038 0.0067
Echinococcus granulosus puromycin sensitive aminopeptidase 0.0024 0.0305 0.0322
Trichomonas vaginalis glyceraldehyde 3-phosphate dehydrogenase, putative 0.012 0.2769 0.6554
Echinococcus multilocularis G protein coupled receptor 139 0.012 0.2775 0.2747
Schistosoma mansoni glyceraldehyde-3-phosphate dehydrogenase (phosphorylating) 0.012 0.2769 0.3528
Loa Loa (eye worm) hypothetical protein 0.012 0.2775 0.484
Schistosoma mansoni hypothetical protein 0.0172 0.4105 0.523
Echinococcus granulosus puromycin sensitive aminopeptidase 0.0024 0.0305 0.0322
Echinococcus multilocularis somatostatin receptor 0.012 0.2775 0.2747
Echinococcus granulosus lamin dm0 0.0014 0.0059 0.0026
Loa Loa (eye worm) hypothetical protein 0.012 0.2775 0.484
Brugia malayi hypothetical protein 0.012 0.2775 0.4805
Trypanosoma cruzi aminopeptidase, putative 0.0024 0.0305 0.0743
Echinococcus granulosus leucyl aminopeptidase 0.0021 0.0228 0.0228
Echinococcus granulosus neuropeptide s receptor 0.012 0.2775 0.3302
Echinococcus multilocularis neuropeptide s receptor 0.012 0.2775 0.2747
Brugia malayi AKH receptor 0.012 0.2775 0.4805
Plasmodium falciparum glyceraldehyde-3-phosphate dehydrogenase 0.012 0.2769 1
Echinococcus multilocularis neuropeptide receptor 0.012 0.2775 0.2747
Leishmania major glyceraldehyde 3-phosphate dehydrogenase, glycosomal 0.012 0.2769 0.6606
Loa Loa (eye worm) nuclear hormone receptor family member nhr-31 0.0014 0.0038 0.0067
Brugia malayi Serotonin/octopamine receptor family protein 7 0.012 0.2775 0.4805
Entamoeba histolytica glyceraldehyde-3-phosphate dehydrogenase, putative 0.012 0.2769 0.6623
Leishmania major aminopeptidase, putative,metallo-peptidase, Clan MF, Family M17 0.0021 0.0228 0.0151
Mycobacterium leprae Probable cytosol aminopeptidase PepB 0.0105 0.2387 1
Schistosoma mansoni opsin-like receptor 0.012 0.2775 0.3536
Onchocerca volvulus 0.012 0.2775 1
Loa Loa (eye worm) aminopeptidase N 0.0024 0.0305 0.0532
Echinococcus multilocularis tachykinin peptides receptor 99D 0.012 0.2775 0.2747
Schistosoma mansoni nuclear hormone receptor 0.0014 0.0038 0.0049
Schistosoma mansoni rhodopsin-like orphan GPCR 0.012 0.2775 0.3536
Brugia malayi Melatonin receptor type 1A 0.012 0.2775 0.4805
Echinococcus granulosus g protein coupled receptor 0.012 0.2775 0.3302
Schistosoma mansoni amine GPCR 0.012 0.2775 0.3536
Toxoplasma gondii glyceraldehyde-3-phosphate dehydrogenase GAPDH1 0.012 0.2769 1
Brugia malayi hypothetical protein 0.012 0.2775 0.4805
Brugia malayi Ubiquitin carboxyl-terminal hydrolase family protein 0.0021 0.0228 0.0332
Onchocerca volvulus 0.012 0.2775 1
Onchocerca volvulus 0.0019 0.0168 0.0474
Trypanosoma brucei PAB1-binding protein , putative 0.0026 0.0356 0.0244
Onchocerca volvulus 0.012 0.2775 1
Echinococcus multilocularis peptide (allatostatin:somatostatin) 0.012 0.2775 0.2747
Mycobacterium ulcerans aminopeptidase N PepN 0.0024 0.0305 0.0471
Echinococcus granulosus rhodopsin orphan GPCR 0.012 0.2775 0.3302
Echinococcus granulosus G protein coupled receptor 139 0.012 0.2775 0.3302
Echinococcus granulosus thyrotropin releasing hormone receptor 0.012 0.2775 0.3302
Echinococcus granulosus rhodopsin orphan GPCR 0.012 0.2775 0.3302
Loa Loa (eye worm) hypothetical protein 0.012 0.2775 0.484
Loa Loa (eye worm) hypothetical protein 0.012 0.2775 0.484
Echinococcus multilocularis puromycin sensitive aminopeptidase 0.0024 0.0305 0.0268
Brugia malayi follicle stimulating hormone receptor 0.012 0.2775 0.4805
Brugia malayi hypothetical protein 0.012 0.2775 0.4805
Schistosoma mansoni lamin 0.0014 0.0059 0.0076
Loa Loa (eye worm) steroid hormone receptor 0.0014 0.0038 0.0067
Schistosoma mansoni neuropeptide receptor 0.012 0.2775 0.3536
Onchocerca volvulus 0.0119 0.275 0.9908
Schistosoma mansoni hypothetical protein 0.0318 0.7849 1
Brugia malayi Niemann-Pick C1 protein precursor 0.0049 0.0942 0.1586
Echinococcus granulosus neuropeptide receptor 0.012 0.2775 0.3302
Schistosoma mansoni hypothetical protein 0.012 0.2775 0.3536
Loa Loa (eye worm) hypothetical protein 0.012 0.2775 0.484
Loa Loa (eye worm) hypothetical protein 0.012 0.2775 0.484
Trypanosoma brucei RNA helicase, putative 0.0318 0.7849 1
Onchocerca volvulus 0.012 0.2775 1
Schistosoma mansoni hypothetical protein 0.002 0.0208 0.0265
Schistosoma mansoni neuropeptide receptor 0.012 0.2775 0.3536
Trichomonas vaginalis Clan MA, family M1, aminopeptidase N-like metallopeptidase 0.0024 0.0305 0.0201
Echinococcus multilocularis rhodopsin orphan GPCR 0.012 0.2775 0.2747
Onchocerca volvulus Huntingtin homolog 0.0057 0.1143 0.4038
Brugia malayi Iron-sulfur cluster assembly accessory protein 0.0048 0.0923 0.1553
Echinococcus granulosus tachykinin peptides receptor 99D 0.012 0.2775 0.3302
Leishmania major hypothetical protein, conserved 0.0026 0.0356 0.0477
Echinococcus granulosus g protein linked acetylcholine receptor gar 2a 0.012 0.2775 0.3302
Echinococcus multilocularis musashi 0.0014 0.0059 0.0021
Echinococcus multilocularis G protein coupled 5 hydroxytryptamine receptor 0.012 0.2775 0.2747
Loa Loa (eye worm) hypothetical protein 0.012 0.2775 0.484
Schistosoma mansoni peptide (allatostatin/somatostatin)-like receptor 0.012 0.2775 0.3536
Loa Loa (eye worm) hypothetical protein 0.012 0.2775 0.484
Onchocerca volvulus 0.012 0.2775 1
Echinococcus granulosus glyceraldehyde 3 phosphate dehydrogenase 0.012 0.2769 0.3294
Brugia malayi hypothetical protein 0.012 0.2775 0.4805
Plasmodium vivax glyceraldehyde-3-phosphate dehydrogenase, putative 0.012 0.2769 1
Schistosoma mansoni biogenic amine (dopamine) receptor 0.012 0.2775 0.3536
Echinococcus granulosus Basic leucine zipper bZIP transcription 0.0018 0.0148 0.0132
Schistosoma mansoni glyceraldehyde-3-phosphate dehydrogenase (phosphorylating) 0.012 0.2769 0.3528
Loa Loa (eye worm) hypothetical protein 0.012 0.2775 0.484
Onchocerca volvulus 0.0014 0.0059 0.0077
Echinococcus multilocularis leucyl aminopeptidase 0.0021 0.0228 0.019
Brugia malayi G protein-coupled receptor F59B2.13 0.012 0.2775 0.4805
Schistosoma mansoni rhodopsin-like orphan GPCR 0.012 0.2775 0.3536
Trypanosoma cruzi PAB1-binding protein , putative 0.0026 0.0356 0.0867
Echinococcus multilocularis protein patched 0.0021 0.0227 0.019
Loa Loa (eye worm) unidentified vitellogenin-linked transcript protein 6 0.012 0.2775 0.484
Echinococcus multilocularis rhodopsin orphan GPCR 0.012 0.2775 0.2747
Onchocerca volvulus 0.012 0.2775 1
Echinococcus multilocularis neuropeptide FF receptor 2 0.012 0.2775 0.2747
Echinococcus multilocularis pyroglutamylated rfamide peptide receptor 0.012 0.2775 0.2747
Echinococcus multilocularis serotonin receptor 0.012 0.2775 0.2747
Schistosoma mansoni nuclear hormone receptor nor-1/nor-2 0.0014 0.0038 0.0049
Leishmania major glyceraldehyde 3-phosphate dehydrogenase, glycosomal 0.012 0.2769 0.6606
Trypanosoma cruzi DNA repair and recombination helicase protein PIF7, putative 0.0172 0.4105 1
Brugia malayi hypothetical protein 0.012 0.2775 0.4805
Schistosoma mansoni patched 1 0.0021 0.0227 0.029
Trypanosoma cruzi glyceraldehyde 3-phosphate dehydrogenase, cytosolic, putative 0.0037 0.0644 0.1568
Echinococcus granulosus orexin receptor type 2 0.012 0.2775 0.3302
Brugia malayi Aminopeptidase ZK353.6 in chromosome III 0.0021 0.0228 0.0332
Trypanosoma cruzi glyceraldehyde 3-phosphate dehydrogenase, putative 0.0037 0.0644 0.1568
Echinococcus granulosus rhodopsin orphan GPCR 0.012 0.2775 0.3302
Echinococcus granulosus rhodopsin orphan GPCR 0.012 0.2775 0.3302
Schistosoma mansoni amine GPCR 0.012 0.2775 0.3536
Echinococcus granulosus tm gpcr rhodopsin 0.012 0.2775 0.3302
Schistosoma mansoni PwLAP aminopeptidase (M17 family) 0.0021 0.0228 0.029
Trypanosoma brucei glyceraldehyde 3-phosphate dehydrogenase, cytosolic 0.012 0.2769 0.3386
Loa Loa (eye worm) hypothetical protein 0.012 0.2775 0.484
Brugia malayi G protein-coupled receptor 0.012 0.2775 0.4805
Echinococcus multilocularis Niemann Pick C1 protein 0.007 0.1479 0.1446
Echinococcus multilocularis geminin 0.0162 0.3855 0.3831
Schistosoma mansoni biogenic amine receptor 0.012 0.2775 0.3536
Trypanosoma cruzi glyceraldehyde-3-phosphate dehydrogenase, putative 0.0078 0.1706 0.4154
Echinococcus multilocularis puromycin sensitive aminopeptidase 0.0024 0.0305 0.0268
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.012 0.2775 0.2747
Echinococcus multilocularis neuropeptides capa receptor 0.012 0.2775 0.2747
Trichomonas vaginalis glyceraldehyde 3-phosphate dehydrogenase, putative 0.012 0.2769 0.6554
Loa Loa (eye worm) hypothetical protein 0.012 0.2775 0.484
Trypanosoma cruzi glyceraldehyde-3-phosphate dehydrogenase, putative 0.0078 0.1706 0.4154
Brugia malayi neuropeptide F receptor 0.012 0.2775 0.4805
Brugia malayi G-protein coupled receptor 0.012 0.2775 0.4805
Brugia malayi MH2 domain containing protein 0.0059 0.1208 0.2053
Loa Loa (eye worm) hypothetical protein 0.012 0.2775 0.484
Loa Loa (eye worm) hypothetical protein 0.012 0.2775 0.484
Trypanosoma cruzi glyceraldehyde 3-phosphate dehydrogenase, cytosolic, putative 0.012 0.2769 0.6745
Onchocerca volvulus Dopamine\/Ecdysteroid receptor homolog 0.012 0.2775 1
Echinococcus granulosus g protein coupled receptor 0.012 0.2775 0.3302
Brugia malayi hypothetical protein 0.012 0.2775 0.4805
Schistosoma mansoni amine GPCR 0.012 0.2775 0.3536
Schistosoma mansoni survival motor neuron protein 0.0048 0.0923 0.1176
Brugia malayi hypothetical protein 0.0235 0.5734 1
Brugia malayi RE15519p 0.012 0.2775 0.4805
Loa Loa (eye worm) nuclear hormone receptor family member nhr-14 0.0014 0.0038 0.0067
Loa Loa (eye worm) hypothetical protein 0.0014 0.0038 0.0067
Trypanosoma brucei DNA repair and recombination helicase protein PIF7 0.0172 0.4105 0.5126
Echinococcus multilocularis g protein coupled receptor 0.012 0.2775 0.2747
Loa Loa (eye worm) glyceraldehyde-3-phosphate dehydrogenase 0.0083 0.1815 0.3165
Echinococcus multilocularis biogenic amine (5HT) receptor 0.012 0.2775 0.2747
Loa Loa (eye worm) hypothetical protein 0.0026 0.0348 0.0607
Loa Loa (eye worm) follicle stimulating hormone receptor 0.012 0.2775 0.484
Schistosoma mansoni histamine h1 receptor 0.012 0.2775 0.3536
Schistosoma mansoni thyrotropin-releasing hormone receptor 0.012 0.2775 0.3536
Brugia malayi hypothetical protein 0.0026 0.0356 0.0557
Schistosoma mansoni ancient conserved domain protein 2 (cyclin m2) 0.012 0.2775 0.3536
Loa Loa (eye worm) abnormal chemotaxis protein 14 0.0021 0.0227 0.0396
Echinococcus granulosus neuropeptides capa receptor 0.012 0.2775 0.3302
Onchocerca volvulus 0.012 0.2775 1
Echinococcus granulosus puromycin sensitive aminopeptidase 0.0024 0.0305 0.0322
Echinococcus granulosus rhodopsin orphan GPCR 0.012 0.2775 0.3302
Echinococcus multilocularis rhodopsin orphan GPCR 0.012 0.2775 0.2747
Trypanosoma cruzi PAB1-binding protein , putative 0.0026 0.0356 0.0867
Echinococcus multilocularis serotonin receptor 0.012 0.2775 0.2747
Schistosoma mansoni RAR-like nuclear receptor 0.0014 0.0038 0.0049
Loa Loa (eye worm) G-protein coupled receptor 0.012 0.2775 0.484
Echinococcus multilocularis glyceraldehyde 3 phosphate dehydrogenase 0.012 0.2769 0.2741
Loa Loa (eye worm) hypothetical protein 0.012 0.2775 0.484
Trypanosoma cruzi metallo-peptidase, clan MA(E), family M1, putative 0.0024 0.0305 0.0743
Echinococcus granulosus rhodopsin orphan GPCR 0.012 0.2775 0.3302
Echinococcus multilocularis puromycin sensitive aminopeptidase 0.0024 0.0305 0.0268
Echinococcus granulosus tm gpcr rhodopsin 0.012 0.2775 0.3302
Trypanosoma cruzi glyceraldehyde 3-phosphate dehydrogenase, cytosolic, putative 0.012 0.2769 0.6745
Brugia malayi hypothetical protein 0.0087 0.1926 0.3313
Brugia malayi PAS domain containing protein 0.0026 0.0356 0.0558
Loa Loa (eye worm) aminopeptidase in chromosome V 0.0021 0.0228 0.0397
Trypanosoma brucei metallo-peptidase, Clan MF, Family M17 0.0021 0.0228 0.0078
Onchocerca volvulus 0.0049 0.0954 0.3346
Brugia malayi putative neuropeptide receptor 0.012 0.2775 0.4805
Echinococcus multilocularis G-protein coupled receptor, putative 0.012 0.2775 0.2747
Entamoeba histolytica DNA repair and recombination protein, putative 0.0172 0.4105 1
Brugia malayi ORL1-like opioid receptor 0.012 0.2775 0.4805
Brugia malayi Peptidase family M1 containing protein 0.0024 0.0305 0.0468
Loa Loa (eye worm) hypothetical protein 0.012 0.2775 0.484
Wolbachia endosymbiont of Brugia malayi glyceraldehyde-3-phosphate dehydrogenase, GapA 0.012 0.2769 1
Echinococcus multilocularis g protein coupled receptor 0.012 0.2775 0.2747
Echinococcus granulosus allatostatin A receptor 0.012 0.2775 0.3302
Brugia malayi Glyceraldehyde 3-phosphate dehydrogenase 0.012 0.2769 0.4794
Schistosoma mansoni neuropeptide F-like receptor 0.012 0.2775 0.3536
Loa Loa (eye worm) hypothetical protein 0.0049 0.0942 0.1642
Onchocerca volvulus 0.012 0.2775 1
Echinococcus granulosus growth hormone secretagogue receptor type 1 0.012 0.2775 0.3302
Echinococcus granulosus hypothetical protein 0.012 0.2775 0.3302
Echinococcus granulosus peptide allatostatin:somatostatin 0.012 0.2775 0.3302
Echinococcus granulosus tumor protein p63 0.0336 0.8327 1
Trypanosoma cruzi metallo-peptidase, Clan MF, Family M17 0.0021 0.0228 0.0555
Echinococcus granulosus rhodopsin orphan GPCR 0.012 0.2775 0.3302
Echinococcus granulosus Protein patched homolog 1 0.0021 0.0227 0.0228
Loa Loa (eye worm) hypothetical protein 0.012 0.2775 0.484
Echinococcus multilocularis puromycin sensitive aminopeptidase 0.0017 0.0137 0.0099
Schistosoma mansoni peptide (FMRFamide/somatostatin)-like receptor 0.012 0.2775 0.3536
Loa Loa (eye worm) hypothetical protein 0.012 0.2775 0.484
Schistosoma mansoni biogenic amine receptor 0.012 0.2775 0.3536
Echinococcus granulosus neuropeptides capa receptor 0.012 0.2775 0.3302
Echinococcus granulosus biogenic amine 5HT receptor 0.012 0.2775 0.3302
Schistosoma mansoni niemann-pick C1 (NPC1) 0.0049 0.0961 0.1225
Brugia malayi Dopamine receptor protein 1 0.012 0.2775 0.4805
Schistosoma mansoni peptide (FMRFamide/neurokinin-3)-like receptor 0.012 0.2775 0.3536
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.012 0.2775 0.2747
Schistosoma mansoni rhodopsin-like orphan GPCR 0.012 0.2775 0.3536
Trypanosoma brucei aminopeptidase, putative 0.0021 0.0228 0.0078
Trypanosoma cruzi metallo-peptidase, Clan MF, Family M17, putative 0.0105 0.2387 0.5816
Brugia malayi G-protein coupled receptor 0.012 0.2775 0.4805
Brugia malayi sulfakinin receptor protein 0.012 0.2775 0.4805
Schistosoma mansoni thyroid hormone receptor 0.0014 0.0038 0.0049
Leishmania major aminopeptidase-like protein,metallo-peptidase, Clan MA(E), Family M1 0.0024 0.0305 0.0348
Loa Loa (eye worm) glyceraldehyde 3-phosphate dehydrogenase 0.0079 0.1707 0.2977
Brugia malayi Aminopeptidase W07G4.4 in chromosome V 0.0021 0.0228 0.0332
Mycobacterium ulcerans glyceraldehyde 3-phosphate dehydrogenase Gap 0.012 0.2769 1
Loa Loa (eye worm) hypothetical protein 0.0021 0.0227 0.0396
Trichomonas vaginalis glyceraldehyde 3-phosphate dehydrogenase, putative 0.012 0.2769 0.6554
Schistosoma mansoni biogenic amine (5HT) receptor 0.012 0.2775 0.3536
Echinococcus multilocularis growth hormone secretagogue receptor type 1 0.012 0.2775 0.2747
Schistosoma mansoni rhodopsin-like orphan GPCR 0.012 0.2775 0.3536
Loa Loa (eye worm) hypothetical protein 0.012 0.2775 0.484
Schistosoma mansoni myosin xvIII 0.012 0.2775 0.3536
Echinococcus granulosus alpha 1A adrenergic receptor 0.012 0.2775 0.3302
Loa Loa (eye worm) hypothetical protein 0.0014 0.0038 0.0067
Schistosoma mansoni single-minded 0.0026 0.0356 0.0454
Entamoeba histolytica glyceraldehyde-3-phosphate dehydrogenase, putative 0.012 0.2769 0.6623
Schistosoma mansoni leucine aminopeptidase 0.0021 0.0228 0.029
Brugia malayi Tachykinin-like peptides receptor 99D 0.012 0.2775 0.4805
Brugia malayi neuropeptide F receptor 0.012 0.2775 0.4805
Mycobacterium ulcerans leucyl aminopeptidase 0.0105 0.2387 0.8525
Echinococcus multilocularis neuropeptides capa receptor 0.012 0.2775 0.2747
Echinococcus granulosus single minded 2 0.0019 0.0183 0.0175
Leishmania major aminopeptidase, putative,metallo-peptidase, Clan MF, Family M17 0.0021 0.0228 0.0151
Trypanosoma brucei glyceraldehyde 3-phosphate dehydrogenase, glycosomal 0.012 0.2769 0.3386
Echinococcus multilocularis neuropeptide Y receptor 0.012 0.2775 0.2747
Loa Loa (eye worm) hypothetical protein 0.0014 0.0059 0.0104
Schistosoma mansoni photoreceptor-specific nuclear receptor related 0.0014 0.0038 0.0049
Echinococcus multilocularis orexin receptor type 2 0.012 0.2775 0.2747
Brugia malayi intermediate filament protein 0.0014 0.0059 0.0037
Schistosoma mansoni neuropeptide F-like receptor 0.012 0.2775 0.3536
Loa Loa (eye worm) hypothetical protein 0.0049 0.0954 0.1664
Echinococcus granulosus g protein linked acetylcholine receptor gar 2a 0.012 0.2775 0.3302
Loa Loa (eye worm) hypothetical protein 0.012 0.2775 0.484
Loa Loa (eye worm) hypothetical protein 0.012 0.2775 0.484
Trypanosoma cruzi cytosolic leucyl aminopeptidase, putative 0.0105 0.2387 0.5816
Loa Loa (eye worm) hypothetical protein 0.012 0.2775 0.484
Echinococcus multilocularis neuropeptide receptor 0.012 0.2775 0.2747
Schistosoma mansoni cellular tumor antigen P53 0.0049 0.0954 0.1216
Loa Loa (eye worm) hypothetical protein 0.012 0.2775 0.484
Onchocerca volvulus 0.012 0.2775 1
Trypanosoma cruzi glyceraldehyde 3-phosphate dehydrogenase, putative 0.012 0.2769 0.6745
Echinococcus multilocularis rhodopsin orphan GPCR 0.012 0.2775 0.2747
Schistosoma mansoni aryl hydrocarbon receptor 0.0026 0.0356 0.0454
Trichomonas vaginalis glyceraldehyde 3-phosphate dehydrogenase, putative 0.0079 0.1707 0.3816
Echinococcus granulosus lamin 0.0014 0.0059 0.0026
Schistosoma mansoni hypothetical protein 0.0162 0.3855 0.4911
Schistosoma mansoni biogenic amine (dopamine) receptor 0.012 0.2775 0.3536
Echinococcus multilocularis rhodopsin orphan GPCR 0.012 0.2775 0.2747
Echinococcus multilocularis sex peptide receptor 0.012 0.2775 0.2747
Loa Loa (eye worm) hypothetical protein 0.0057 0.1143 0.1994
Echinococcus granulosus Niemann Pick C1 protein 0.007 0.1479 0.1738
Schistosoma mansoni hypothetical protein 0.0048 0.0923 0.1176
Schistosoma mansoni biogenic amine (dopamine) receptor 0.012 0.2775 0.3536
Echinococcus multilocularis rhodopsin orphan GPCR 0.012 0.2775 0.2747
Brugia malayi Serotonin receptor 0.012 0.2775 0.4805
Echinococcus multilocularis Peptidase M1, membrane alanine aminopeptidase, N terminal 0.0024 0.0305 0.0268
Echinococcus multilocularis neuropeptide receptor A26 0.012 0.2775 0.2747
Onchocerca volvulus 0.0048 0.0923 0.3232
Schistosoma mansoni amine GPCR 0.012 0.2775 0.3536
Loa Loa (eye worm) hypothetical protein 0.012 0.2775 0.484
Echinococcus multilocularis expressed conserved protein 0.0046 0.0866 0.0831
Loa Loa (eye worm) hypothetical protein 0.012 0.2775 0.484
Loa Loa (eye worm) nuclear Hormone Receptor family member 0.0014 0.0038 0.0067
Trypanosoma cruzi glyceraldehyde 3-phosphate dehydrogenase, cytosolic, putative 0.012 0.2769 0.6745
Trypanosoma cruzi glyceraldehyde 3-phosphate dehydrogenase, cytosolic, putative 0.0037 0.0644 0.1568
Onchocerca volvulus 0.012 0.2775 1
Loa Loa (eye worm) hypothetical protein 0.012 0.2775 0.484
Echinococcus granulosus puromycin sensitive aminopeptidase 0.0024 0.0305 0.0322
Echinococcus multilocularis g protein linked acetylcholine receptor gar 2a 0.012 0.2775 0.2747
Schistosoma mansoni biogenic amine receptor 0.012 0.2775 0.3536
Echinococcus granulosus neuropeptide receptor 0.012 0.2775 0.3302
Echinococcus granulosus pyroglutamylated rfamide peptide receptor 0.012 0.2775 0.3302
Onchocerca volvulus 0.012 0.2775 1
Schistosoma mansoni steroid hormone receptor ad4bp 0.0014 0.0038 0.0049
Loa Loa (eye worm) hypothetical protein 0.012 0.2775 0.484
Loa Loa (eye worm) hypothetical protein 0.012 0.2775 0.484
Brugia malayi hypothetical protein 0.012 0.2775 0.4805
Loa Loa (eye worm) hypothetical protein 0.012 0.2775 0.484
Echinococcus granulosus g protein coupled receptor 0.012 0.2775 0.3302
Echinococcus multilocularis fmrfamide receptor 0.012 0.2775 0.2747
Trypanosoma cruzi metallo-peptidase, Clan MF, Family M17 0.0021 0.0228 0.0555
Echinococcus multilocularis glyceraldehyde 3 phosphate dehydrogenase 0.012 0.2769 0.2741
Echinococcus granulosus ankyrin repeat domain containing protein 17 0.0021 0.0228 0.0228
Schistosoma mansoni hypothetical protein 0.0024 0.0304 0.0387
Brugia malayi Serotonin receptor 0.012 0.2775 0.4805
Onchocerca volvulus 0.012 0.2775 1
Loa Loa (eye worm) aminopeptidase in chromosome III 0.0021 0.0228 0.0397
Brugia malayi Pax transcription factor protein 2 0.0119 0.275 0.4761
Schistosoma mansoni muscarinic acetylcholine (GAR) receptor 0.012 0.2775 0.3536
Echinococcus granulosus biogenic amine 5HT receptor 0.012 0.2775 0.3302
Giardia lamblia Glyceraldehyde 3-phosphate dehydrogenase 0.012 0.2769 0.4431
Brugia malayi Dopamine receptor protein 1, putative (partial) 0.012 0.2775 0.4805
Plasmodium vivax M17 leucyl aminopeptidase, putative 0.0105 0.2387 0.8419
Loa Loa (eye worm) 5-hydroxytryptamine 2C receptor 0.012 0.2775 0.484
Brugia malayi putative neuropeptide receptor NPR1 0.012 0.2775 0.4805
Trichomonas vaginalis conserved hypothetical protein 0.0172 0.4105 1
Schistosoma mansoni histamine-responsive GPCR (AAF21638) 0.012 0.2775 0.3536
Loa Loa (eye worm) hypothetical protein 0.0014 0.0038 0.0067
Brugia malayi larval opioid receptor 0.012 0.2775 0.4805
Echinococcus multilocularis lamin dm0 0.0014 0.0059 0.0021
Onchocerca volvulus Neuropeptide F receptor homolog 0.012 0.2775 1
Loa Loa (eye worm) hypothetical protein 0.012 0.2775 0.484
Trichomonas vaginalis Clan MA, family M1, aminopeptidase N-like metallopeptidase 0.0024 0.0305 0.0201
Schistosoma mansoni adenoreceptor 0.012 0.2775 0.3536
Loa Loa (eye worm) hypothetical protein 0.012 0.2775 0.484
Echinococcus multilocularis glyceraldehyde 3 phosphate dehydrogenase 0.0079 0.1707 0.1675
Onchocerca volvulus Huntingtin homolog 0.0057 0.1143 0.4038
Brugia malayi gonadotropin-releasing hormone receptor 2 0.012 0.2775 0.4805
Brugia malayi Peptidase family M1 containing protein 0.0019 0.0168 0.0228
Loa Loa (eye worm) hypothetical protein 0.0079 0.1707 0.2977
Entamoeba histolytica Niemann-Pick C1 protein, putative 0.0049 0.0942 0.2007
Trypanosoma cruzi Aminopeptidase M1, putative 0.0019 0.0168 0.0409
Echinococcus multilocularis puromycin sensitive aminopeptidase 0.0024 0.0305 0.0268
Treponema pallidum glyceraldehyde 3-phosphate dehydrogenase (gap) 0.012 0.2769 0.5
Echinococcus multilocularis alpha 1A adrenergic receptor 0.012 0.2775 0.2747
Loa Loa (eye worm) hypothetical protein 0.012 0.2775 0.484
Schistosoma mansoni glyceraldehyde-3-phosphate dehydrogenase (phosphorylating) 0.012 0.2769 0.3528
Echinococcus granulosus 7TM GPCR rhodopsin 0.012 0.2775 0.3302
Loa Loa (eye worm) hypothetical protein 0.012 0.2775 0.484
Schistosoma mansoni coup transcription factor 0.0014 0.0038 0.0049
Schistosoma mansoni rhodopsin-like orphan GPCR 0.012 0.2775 0.3536
Echinococcus granulosus 7tm_1 domain containing protein 0.012 0.2775 0.3302
Echinococcus granulosus sterol regulatory element binding protein 0.0021 0.0227 0.0228
Loa Loa (eye worm) neuropeptide F receptor 0.012 0.2775 0.484
Loa Loa (eye worm) G-protein coupled receptor 0.012 0.2775 0.484
Schistosoma mansoni transcription factor LCR-F1 0.0018 0.0148 0.0188
Echinococcus multilocularis leucyl aminopeptidase 0.0021 0.0228 0.019
Schistosoma mansoni glyceraldehyde-3-phosphate dehydrogenase (phosphorylating) 0.012 0.2769 0.3528
Loa Loa (eye worm) transcription factor SMAD2 0.0059 0.1208 0.2107
Schistosoma mansoni hypothetical protein 0.002 0.0208 0.0265
Schistosoma mansoni biogenic amine (5HT) receptor 0.012 0.2775 0.3536
Schistosoma mansoni Tr4/Tr2 (homologue) 0.0014 0.0038 0.0049
Trichomonas vaginalis glyceraldehyde 3-phosphate dehydrogenase, putative 0.012 0.2769 0.6554
Echinococcus granulosus intermediate filament protein 0.0014 0.0059 0.0026
Loa Loa (eye worm) hypoxia-induced factor 1 0.008 0.1752 0.3056
Schistosoma mansoni biogenic amine (octopamine/dopamine) receptor 0.012 0.2775 0.3536
Schistosoma mansoni retinoid-x-receptor (RXR) 0.0014 0.0038 0.0049
Loa Loa (eye worm) hypothetical protein 0.0014 0.0038 0.0067
Brugia malayi Dopamine receptor 0.012 0.2775 0.4805
Schistosoma mansoni amine GPCR 0.012 0.2775 0.3536
Loa Loa (eye worm) glyceraldehyde 3-phosphate dehydrogenase 0.0079 0.1707 0.2977
Schistosoma mansoni neuropeptide receptor 0.012 0.2775 0.3536
Echinococcus multilocularis rhodopsin orphan GPCR 0.012 0.2775 0.2747
Schistosoma mansoni lamin 0.0014 0.0059 0.0076
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.012 0.2775 0.2747
Schistosoma mansoni opsin-like receptor 0.012 0.2775 0.3536
Schistosoma mansoni growth hormone secretagogue receptor 0.012 0.2775 0.3536
Schistosoma mansoni hypothetical protein 0.002 0.0208 0.0265
Echinococcus multilocularis puromycin sensitive aminopeptidase 0.0024 0.0305 0.0268
Schistosoma mansoni hypothetical protein 0.012 0.2775 0.3536
Loa Loa (eye worm) hypothetical protein 0.012 0.2775 0.484
Schistosoma mansoni cytosol alanyl aminopeptidase (M01 family) 0.0024 0.0305 0.0389
Trypanosoma cruzi glyceraldehyde 3-phosphate dehydrogenase, putative 0.012 0.2769 0.6745
Echinococcus granulosus leucine aminopeptidase protein 0.0105 0.2387 0.2834
Onchocerca volvulus 0.012 0.2775 1
Toxoplasma gondii glyceraldehyde-3-phosphate dehydrogenase GAPDH2 0.012 0.2769 1
Echinococcus multilocularis tumor protein p63 0.0336 0.8327 0.832
Trypanosoma brucei metallo-peptidase, Clan MA(E) Family M1 0.0024 0.0305 0.0178
Schistosoma mansoni rhodopsin-like orphan GPCR 0.012 0.2775 0.3536
Echinococcus multilocularis transfer RNA-Lys 0.0019 0.0183 0.0145
Leishmania major aminopeptidase, putative,metallo-peptidase, Clan MF, Family M17 0.0021 0.0228 0.0151
Brugia malayi CHE-14 protein 0.0021 0.0227 0.0332
Loa Loa (eye worm) hypothetical protein 0.012 0.2775 0.484
Loa Loa (eye worm) neuropeptide F receptor 0.012 0.2775 0.484
Loa Loa (eye worm) intermediate filament tail domain-containing protein 0.0014 0.0059 0.0104
Schistosoma mansoni hypothetical protein 0.012 0.2775 0.3536
Echinococcus granulosus serotonin receptor 0.012 0.2775 0.3302
Schistosoma mansoni neuropeptide f receptor 76f 0.012 0.2775 0.3536
Brugia malayi hypothetical protein 0.012 0.2775 0.4805
Brugia malayi Glyceraldehyde 3-phosphate dehydrogenase 0.0041 0.0752 0.1253
Loa Loa (eye worm) nuclear hormone receptor family member nhr-1 0.0014 0.0038 0.0067
Loa Loa (eye worm) pax transcription factor protein 2 0.0119 0.275 0.4796
Loa Loa (eye worm) gonadotropin-releasing hormone receptor 2 0.012 0.2775 0.484
Loa Loa (eye worm) hypothetical protein 0.012 0.2775 0.484
Brugia malayi hypothetical protein 0.0019 0.0168 0.0228
Brugia malayi Unidentified vitellogenin-linked transcript protein 6, putative 0.012 0.2775 0.4805
Mycobacterium tuberculosis Probable aminopeptidase PepB 0.0105 0.2387 1
Schistosoma mansoni nuclear receptor 2DBD-gamma 0.0014 0.0038 0.0049
Brugia malayi G-protein-linked acetylcholine receptor protein 2, putative 0.012 0.2775 0.4805
Echinococcus granulosus glyceraldehyde 3 phosphate dehydrogenase 0.012 0.2769 0.3294
Trypanosoma cruzi DNA repair and recombination helicase protein PIF6, putative 0.0172 0.4105 1
Loa Loa (eye worm) hypothetical protein 0.012 0.2775 0.484
Echinococcus multilocularis g-protein coupled receptor 0.012 0.2775 0.2747
Schistosoma mansoni peptide (FMRFamide/somatostatin)-like receptor 0.012 0.2775 0.3536
Entamoeba histolytica hypothetical protein, conserved 0.0172 0.4105 1
Loa Loa (eye worm) hypothetical protein 0.012 0.2775 0.484
Trypanosoma cruzi glyceraldehyde 3-phosphate dehydrogenase, C-terminal domain, putative 0.0037 0.0644 0.1568
Echinococcus granulosus sex peptide receptor 0.012 0.2775 0.3302
Loa Loa (eye worm) hypothetical protein 0.012 0.2775 0.484
Echinococcus granulosus leucyl aminopeptidase 0.0021 0.0228 0.0228
Loa Loa (eye worm) MH2 domain-containing protein 0.0059 0.1208 0.2107
Toxoplasma gondii leucyl aminopeptidase LAP 0.0105 0.2387 0.8419
Echinococcus granulosus neuropeptide Y receptor 0.012 0.2775 0.3302
Schistosoma mansoni peptide (allatostatin)-like receptor 0.012 0.2775 0.3536
Schistosoma mansoni retinoic acid receptor RXR 0.0014 0.0038 0.0049
Loa Loa (eye worm) hypothetical protein 0.012 0.2775 0.484
Echinococcus multilocularis aminopeptidase N 0.0019 0.0168 0.013
Trypanosoma brucei glyceraldehyde 3-phosphate dehydrogenase, glycosomal 0.012 0.2769 0.3386
Schistosoma mansoni hypothetical protein 0.002 0.0208 0.0265
Echinococcus granulosus neuropeptide receptor A26 0.012 0.2775 0.3302
Leishmania major PIF1 helicase-like protein, putative,DNA repair and recombination protein, mitochondrial precursor, putative 0.0172 0.4105 1
Loa Loa (eye worm) hypothetical protein 0.012 0.2775 0.484
Schistosoma mansoni alpha-1 adrenergic receptor 0.012 0.2775 0.3536
Brugia malayi hypothetical protein 0.0057 0.1143 0.194
Trypanosoma cruzi glyceraldehyde 3-phosphate dehydrogenase, C-terminal domain, putative 0.0037 0.0644 0.1568
Schistosoma mansoni opsin-like receptor 0.012 0.2775 0.3536
Trichomonas vaginalis glyceraldehyde 3-phosphate dehydrogenase, putative 0.012 0.2769 0.6554
Trypanosoma brucei metallo-peptidase, Clan MF, Family M17 0.0105 0.2387 0.289
Echinococcus granulosus dro:myosuppressin receptor 0.012 0.2775 0.3302
Schistosoma mansoni hypothetical protein 0.0162 0.3855 0.4911
Loa Loa (eye worm) hypothetical protein 0.0014 0.0038 0.0067
Onchocerca volvulus 0.0019 0.0183 0.053
Loa Loa (eye worm) nuclear hormone receptor family member nhr-49 0.0014 0.0038 0.0067
Echinococcus multilocularis allatostatin A receptor 0.012 0.2775 0.2747
Giardia lamblia Rrm3p helicase 0.0172 0.4105 1
Echinococcus multilocularis sterol regulatory element binding protein 0.0021 0.0227 0.019
Echinococcus multilocularis rhodopsin orphan GPCR 0.012 0.2775 0.2747
Brugia malayi hypothetical protein 0.0017 0.012 0.0143
Schistosoma mansoni hypothetical protein 0.012 0.2775 0.3536
Loa Loa (eye worm) melatonin receptor type 1A 0.012 0.2775 0.484
Echinococcus multilocularis leucine aminopeptidase protein 0.0105 0.2387 0.2358
Schistosoma mansoni rhodopsin-like orphan GPCR 0.012 0.2775 0.3536
Onchocerca volvulus 0.012 0.2775 1
Schistosoma mansoni rhodopsin-like orphan GPCR 0.012 0.2775 0.3536
Loa Loa (eye worm) hypothetical protein 0.0235 0.5734 1
Brugia malayi hypothetical protein 0.0018 0.0148 0.0192
Brugia malayi hypothetical protein 0.012 0.2775 0.4805
Brugia malayi cytosol aminopeptidase 0.0021 0.0228 0.0332
Schistosoma mansoni rhodopsin-like orphan GPCR 0.012 0.2775 0.3536
Onchocerca volvulus 0.012 0.2775 1
Trypanosoma brucei metallo-peptidase, Clan MF, Family M17 0.0021 0.0228 0.0078
Echinococcus multilocularis Niemann Pick C1 protein 0.0049 0.0942 0.0907
Trypanosoma cruzi DNA repair and recombination helicase protein PIF7, putative 0.0172 0.4105 1
Echinococcus multilocularis g protein coupled receptor 0.012 0.2775 0.2747
Entamoeba histolytica aminopeptidase, putative 0.0024 0.0305 0.0398
Echinococcus multilocularis g protein linked acetylcholine receptor gar 2a 0.012 0.2775 0.2747
Schistosoma mansoni hypothetical protein 0.0018 0.0148 0.0188
Loa Loa (eye worm) TYRA-2 protein 0.012 0.2775 0.484
Echinococcus granulosus neuropeptide FF receptor 2 0.012 0.2775 0.3302
Schistosoma mansoni neuropeptide receptor 0.012 0.2775 0.3536
Schistosoma mansoni thyroid hormone receptor 0.0014 0.0038 0.0049
Loa Loa (eye worm) hypothetical protein 0.012 0.2775 0.484
Trypanosoma cruzi glyceraldehyde 3-phosphate dehydrogenase, putative 0.012 0.2769 0.6745
Echinococcus granulosus glyceraldehyde 3 phosphate dehydrogenase 0.0079 0.1707 0.2014
Loa Loa (eye worm) hypothetical protein 0.0026 0.0356 0.0621
Trypanosoma brucei glyceraldehyde-3-phosphate dehydrogenase, putative 0.0078 0.1706 0.2002
Loa Loa (eye worm) hypothetical protein 0.0014 0.0038 0.0067
Echinococcus granulosus neuropeptide Y receptor 0.012 0.2775 0.3302
Echinococcus granulosus fmrfamide receptor 0.012 0.2775 0.3302
Echinococcus multilocularis ATP dependent DNA helicase PIF1 0.0172 0.4105 0.4083
Leishmania major PIF1 helicase-like protein, putative,DNA repair and recombination protein, mitochondrial precursor, putative 0.0172 0.4105 1
Trypanosoma cruzi glyceraldehyde 3-phosphate dehydrogenase, putative 0.012 0.2769 0.6745
Echinococcus multilocularis neuropeptide Y receptor 0.012 0.2775 0.2747
Chlamydia trachomatis glyceraldehyde-3-phosphate dehydrogenase 0.012 0.2769 1
Brugia malayi hypoxia-induced factor 1 0.008 0.1752 0.3009
Onchocerca volvulus 0.0019 0.0168 0.0474
Echinococcus granulosus survival motor neuron protein 1 0.0235 0.5734 0.6872
Plasmodium falciparum M17 leucyl aminopeptidase 0.0105 0.2387 0.8419
Schistosoma mansoni FTZ-F1 nuclear receptor-like protein 0.0014 0.0038 0.0049
Brugia malayi bHLH-PAS transcription factor 0.0019 0.0183 0.0254
Echinococcus granulosus aminopeptidase N 0.0019 0.0168 0.0156
Entamoeba histolytica glyceraldehyde-3-phosphate dehydrogenase, putative 0.012 0.2769 0.6623
Schistosoma mansoni aminopeptidase PILS (M01 family) 0.0019 0.0168 0.0214
Loa Loa (eye worm) hypothetical protein 0.0014 0.0053 0.0092
Leishmania major cytosolic leucyl aminopeptidase,metallo-peptidase, Clan MF, Family M17 0.0105 0.2387 0.5637
Leishmania major glyceraldehyde-3-phosphate dehydrogenase-like protein 0.0078 0.1706 0.3905
Brugia malayi glyceraldehyde 3-phosphate dehydrogenase 0.0037 0.0644 0.1063
Trypanosoma brucei DNA repair and recombination helicase protein PIF6 0.0172 0.4105 0.5126
Loa Loa (eye worm) hypothetical protein 0.012 0.2775 0.484
Echinococcus granulosus somatostatin receptor 0.012 0.2775 0.3302
Schistosoma mansoni intermediate filament proteins 0.0014 0.0059 0.0076
Loa Loa (eye worm) hypothetical protein 0.0014 0.0038 0.0067
Echinococcus granulosus ATP dependent DNA helicase PIF1 0.0172 0.4105 0.4907
Loa Loa (eye worm) hypothetical protein 0.0014 0.0038 0.0067
Echinococcus granulosus tm gpcr rhodopsin 0.012 0.2775 0.3302
Onchocerca volvulus 0.012 0.2775 1
Echinococcus multilocularis lamin 0.0014 0.0059 0.0021
Brugia malayi Dopamine receptor protein 2 0.012 0.2775 0.4805
Echinococcus granulosus geminin 0.0162 0.3855 0.4604
Loa Loa (eye worm) hypothetical protein 0.012 0.2775 0.484
Brugia malayi Intermediate filament tail domain containing protein 0.0014 0.0059 0.0037
Loa Loa (eye worm) hypothetical protein 0.012 0.2775 0.484
Loa Loa (eye worm) hypothetical protein 0.0087 0.1926 0.3358
Loa Loa (eye worm) hypothetical protein 0.0057 0.1143 0.1994
Trichomonas vaginalis glyceraldehyde 3-phosphate dehydrogenase, putative 0.0079 0.1707 0.3816
Echinococcus multilocularis Basic leucine zipper (bZIP) transcription 0.0018 0.0148 0.011
Loa Loa (eye worm) intermediate filament protein 0.0014 0.0059 0.0104
Loa Loa (eye worm) glyceraldehyde-3-phosphate dehydrogenase 0.0083 0.1815 0.3165
Echinococcus granulosus g-protein coupled receptor 0.012 0.2775 0.3302
Loa Loa (eye worm) hypothetical protein 0.012 0.2775 0.484
Brugia malayi GnHR receptor homolog 0.012 0.2775 0.4805
Echinococcus granulosus G protein coupled 5 hydroxytryptamine receptor 0.012 0.2775 0.3302
Echinococcus granulosus expressed conserved protein 0.0046 0.0866 0.0998
Trichomonas vaginalis glyceraldehyde 3-phosphate dehydrogenase, putative 0.0041 0.0752 0.1352
Onchocerca volvulus 0.0014 0.0059 0.0077
Echinococcus multilocularis leucyl aminopeptidase 0.0021 0.0228 0.019
Echinococcus multilocularis survival motor neuron protein 1 0.0235 0.5734 0.5718
Echinococcus multilocularis dro:myosuppressin receptor 0.012 0.2775 0.2747
Loa Loa (eye worm) G-protein-linked acetylcholine receptor protein 2 0.012 0.2775 0.484
Brugia malayi hypothetical protein 0.012 0.2775 0.4805
Echinococcus multilocularis thyrotropin releasing hormone receptor 0.012 0.2775 0.2747
Echinococcus multilocularis 7TM GPCR, rhodopsin 0.012 0.2775 0.2747
Onchocerca volvulus 0.012 0.2775 1
Echinococcus multilocularis fmrfamide receptor 0.012 0.2775 0.2747

Activities

Activity type Activity value Assay description Source Reference
Relative potency (functional) = 0.01 Melanotropic potency against Rana pipiens using frog skin bioassay; effect did not continue after the removal of the compound ChEMBL. 2555512
Relative potency (functional) = 5 Melanotropic potency against Anolis carolinensis using lizard skin bioassay; effect did not continue after the removal of the compound ChEMBL. 2555512
Relative potency (functional) = 0.01 Melanotropic potency against Rana pipiens using frog skin bioassay; effect did not continue after the removal of the compound ChEMBL. 2555512
Relative potency (functional) = 5 Melanotropic potency against Anolis carolinensis using lizard skin bioassay; effect did not continue after the removal of the compound ChEMBL. 2555512

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
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External resources for this compound

Bibliographic References

1 literature reference was collected for this gene.

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