Detailed information for compound 401594

Basic information

Technical information
  • Name: Unnamed compound
  • MW: 1011 | Formula: C41H62N12O18
  • H donors: 16 H acceptors: 20 LogP: -9.47 Rotable bonds: 23
    Rule of 5 violations (Lipinski): 4
  • SMILES: NCCCCC[C@@H](C(=O)O)NC(=O)[C@@H]1CCCC[C@H](NC(=O)[C@@H](CC(=O)O)NC(=O)[C@H](CO)NC(=O)c2c(C(=O)N[C@@H](C(=O)N[C@@H](C(=O)N1)CC(=O)O)CO)nccn2)C(=O)N[C@H](C(=O)O)CCCCN
  • InChi: 1S/C41H62N12O18/c42-12-6-1-2-10-22(40(68)69)48-32(60)20-8-3-4-9-21(33(61)49-23(41(70)71)11-5-7-13-43)47-35(63)25(17-29(58)59)51-37(65)27(19-55)53-39(67)31-30(44-14-15-45-31)38(66)52-26(18-54)36(64)50-24(16-28(56)57)34(62)46-20/h14-15,20-27,54-55H,1-13,16-19,42-43H2,(H,46,62)(H,47,63)(H,48,60)(H,49,61)(H,50,64)(H,51,65)(H,52,66)(H,53,67)(H,56,57)(H,58,59)(H,68,69)(H,70,71)/t20-,21-,22-,23-,24+,25+,26+,27-/m0/s1
  • InChiKey: WVKFKVOSPQQOIE-OFRBFVRISA-N  


Substructure search Similarity search

Network

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Synonyms

No synonyms found for this compound

Targets

Known targets for this compound

No curated genes were found associated with this compound

Predicted pathogen targets for this compound

By orthology
No druggable targets predicted by orthology data
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Leishmania major hypothetical protein, conserved 0.0038 0.0205 0.0259
Echinococcus granulosus rhodopsin orphan GPCR 0.0209 0.1793 0.1787
Onchocerca volvulus 0.0053 0.0347 0.1322
Brugia malayi hypothetical protein 0.0209 0.1793 0.2822
Toxoplasma gondii hypothetical protein 0.0019 0.0032 0.0033
Echinococcus granulosus Glutamate receptor ionotropic kainate 2 0.0198 0.1688 0.1682
Echinococcus multilocularis transient receptor potential cation channel 0.0038 0.0205 0.0199
Loa Loa (eye worm) nuclear hormone receptor family member nhr-14 0.0022 0.0057 0.0097
Plasmodium vivax DNA gyrase subunit A, putative 0.0032 0.0155 0.0249
Schistosoma mansoni peptide (FMRFamide/neurokinin-3)-like receptor 0.0209 0.1793 0.1932
Brugia malayi hypothetical protein 0.0209 0.1793 0.2822
Plasmodium falciparum thioredoxin reductase 0.063 0.5689 1
Echinococcus granulosus sodium channel protein 0.0456 0.4077 0.4073
Loa Loa (eye worm) hepatopoietin HPO2 0.0037 0.0197 0.0334
Echinococcus granulosus fmrfamide receptor 0.0209 0.1793 0.1787
Echinococcus granulosus growth hormone secretagogue receptor type 1 0.0209 0.1793 0.1787
Brugia malayi Pre-SET motif family protein 0.0033 0.0159 0.025
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0019 0.0035 0.0118
Loa Loa (eye worm) thioredoxin reductase 0.063 0.5689 0.9648
Schistosoma mansoni neuropeptide F-like receptor 0.0209 0.1793 0.1932
Brugia malayi putative neuropeptide receptor 0.0209 0.1793 0.2822
Echinococcus granulosus ryanodine receptor 44f 0.0038 0.0205 0.0199
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0019 0.0035 0.0118
Loa Loa (eye worm) hypothetical protein 0.0087 0.0667 0.113
Loa Loa (eye worm) hypothetical protein 0.0525 0.4724 0.8011
Trichomonas vaginalis PIKK family atypical protein kinase 0.0028 0.0121 0.041
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0313 0.2754 0.9369
Echinococcus multilocularis pyridine nucleotide disulfide oxidoreductase 0.0088 0.0675 0.0669
Toxoplasma gondii inositol(myo)-1(or 4)-monophosphatase 2, putative 0.004 0.0223 0.0369
Brugia malayi Dopamine receptor protein 1 0.0652 0.5896 0.9282
Echinococcus granulosus g-protein coupled receptor 0.0209 0.1793 0.1787
Onchocerca volvulus Putative DNA topoisomerase 2, mitochondrial 0.0101 0.0793 0.3352
Echinococcus granulosus Transcription factor JmjC domain containing protein 0.0102 0.0803 0.0798
Schistosoma mansoni neuropeptide F-like receptor 0.0209 0.1793 0.1932
Trichomonas vaginalis myo inositol monophosphatase, putative 0.004 0.0223 0.0759
Trypanosoma brucei apurinic/apyrimidinic endonuclease, putative 0.002 0.0043 0.0048
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0033 0.0159 0.0165
Loa Loa (eye worm) hypothetical protein 0.0209 0.1793 0.304
Echinococcus multilocularis FTZ F1 nuclear receptor protein 0.0022 0.0057 0.0051
Schistosoma mansoni high voltage-activated calcium channel Cav1 0.0138 0.1133 0.1219
Onchocerca volvulus 0.0044 0.0264 0.0942
Trichomonas vaginalis PIKK family atypical protein kinase 0.0016 0.0006 0.0022
Mycobacterium tuberculosis Probable glutamine-binding lipoprotein GlnH (GLNBP) 0.004 0.0232 0.0384
Mycobacterium tuberculosis DNA gyrase (subunit B) GyrB (DNA topoisomerase (ATP-hydrolysing)) (DNA topoisomerase II) (type II DNA topoisomerase) 0.0087 0.0665 0.1148
Entamoeba histolytica glutamate synthase beta subunit, putative 0.0088 0.0675 0.2331
Loa Loa (eye worm) doublecortin family protein 0.0042 0.0248 0.042
Schistosoma mansoni transient receptor potential cation channel subfamily m member 0.0038 0.0205 0.0215
Echinococcus granulosus rhodopsin orphan GPCR 0.0209 0.1793 0.1787
Brugia malayi hypothetical protein 0.0209 0.1793 0.2822
Schistosoma mansoni glutamate receptor NMDA 0.0282 0.2469 0.2663
Echinococcus granulosus serotonin receptor 0.0209 0.1793 0.1787
Loa Loa (eye worm) hypothetical protein 0.0038 0.0205 0.0347
Schistosoma mansoni hypothetical protein 0.0209 0.1793 0.1932
Echinococcus multilocularis diuretic hormone 44 receptor GPRdih2 0.0017 0.0013 0.0007
Mycobacterium ulcerans NADPH dependent 2,4-dienoyl-CoA reductase FadH 0.0088 0.0675 0.2181
Brugia malayi DNA-(Apurinic or apyrimidinic site) lyase 0.0082 0.0617 0.0971
Trichomonas vaginalis conserved hypothetical protein 0.0016 0.0005 0.0016
Schistosoma mansoni voltage-gated cation channel 0.0138 0.1133 0.1219
Echinococcus granulosus potassium large conductance calcium activated 0.0038 0.0205 0.0199
Trichomonas vaginalis PIKK family atypical protein kinase 0.0026 0.0098 0.0332
Brugia malayi ORL1-like opioid receptor 0.0209 0.1793 0.2822
Echinococcus granulosus lamin 0.0029 0.0124 0.0118
Brugia malayi Sodium:neurotransmitter symporter family protein 0.0044 0.0264 0.0415
Echinococcus multilocularis GPCR, family 2 0.0017 0.0013 0.0007
Loa Loa (eye worm) hypothetical protein 0.0026 0.0102 0.0172
Echinococcus granulosus voltage dependent L type calcium channel subunit|voltage dependent calcium channel 0.0138 0.1133 0.1128
Schistosoma mansoni voltage-gated potassium channel 0.0046 0.0287 0.0303
Echinococcus multilocularis fmrfamide receptor 0.0209 0.1793 0.1787
Echinococcus multilocularis tachykinin peptides receptor 99D 0.0209 0.1793 0.1787
Treponema pallidum thioredoxin reductase (trxB) 0.0088 0.0675 0.2181
Loa Loa (eye worm) hypothetical protein 0.0038 0.0208 0.0351
Loa Loa (eye worm) PHD-finger family protein 0.0031 0.0146 0.0247
Schistosoma mansoni glutamate synthase 0.0088 0.0675 0.0723
Toxoplasma gondii histone lysine methyltransferase SET1 0.0059 0.0407 0.0693
Echinococcus multilocularis rhodopsin orphan GPCR 0.0209 0.1793 0.1787
Trypanosoma cruzi dihydrolipoyl dehydrogenase, putative 0.0333 0.2939 0.3829
Echinococcus multilocularis potassium voltage gated channel subfamily C 0.0038 0.0205 0.0199
Echinococcus granulosus two pore calcium channel protein 1 0.0038 0.0205 0.0199
Wolbachia endosymbiont of Brugia malayi fructose-1,6-bisphosphatase 0.004 0.0223 0.062
Echinococcus granulosus NADP dependent isocitrate dehydrogenase 0.0017 0.0014 0.0007
Schistosoma mansoni voltage-gated potassium channel 0.0078 0.058 0.062
Schistosoma mansoni amine GPCR 0.0209 0.1793 0.1932
Treponema pallidum fructose-bisphosphate aldolase 0.0313 0.2754 0.936
Schistosoma mansoni hypothetical protein 0.0017 0.0013 0.0008
Trichomonas vaginalis ap endonuclease, putative 0.002 0.0043 0.0148
Plasmodium falciparum thioredoxin reductase 0.0333 0.2939 0.5155
Onchocerca volvulus 0.0089 0.0681 0.2842
Echinococcus granulosus tumor protein p63 0.0362 0.3206 0.3202
Echinococcus multilocularis DNA (apurinic or apyrimidinic site) lyase 0.002 0.0043 0.0037
Plasmodium falciparum amino acid transporter, putative 0.0044 0.0264 0.0441
Trypanosoma cruzi PAB1-binding protein , putative 0.0027 0.0107 0.0131
Loa Loa (eye worm) hypothetical protein 0.0024 0.0083 0.014
Schistosoma mansoni hypothetical protein 0.0017 0.0013 0.0008
Echinococcus multilocularis potassium:sodium hyperpolarization activated 0.0043 0.0253 0.0247
Echinococcus granulosus potassium voltage gated channel subfamily D 0.0038 0.0205 0.0199
Echinococcus granulosus apoptosis inducing factor 1 mitochondrial 0.0088 0.0675 0.0669
Loa Loa (eye worm) receptor family ligand binding region containing protein 0.0024 0.0083 0.014
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0313 0.2754 0.9369
Echinococcus multilocularis conserved hypothetical protein 0.0038 0.0205 0.0199
Schistosoma mansoni nuclear hormone receptor nor-1/nor-2 0.0022 0.0057 0.0055
Loa Loa (eye worm) hypothetical protein 0.0138 0.1133 0.1922
Trichomonas vaginalis PIKK family atypical protein kinase 0.0026 0.0097 0.0331
Loa Loa (eye worm) hypothetical protein 0.0061 0.0421 0.0713
Plasmodium vivax amine transporter, putative 0.0044 0.0264 0.0441
Schistosoma mansoni cpg binding protein 0.0031 0.0142 0.0146
Trypanosoma brucei target of rapamycin kinase 3, putative 0.0038 0.0212 0.0268
Schistosoma mansoni biogenic amine (5HT) receptor 0.1015 0.9254 1
Onchocerca volvulus 0.0209 0.1793 0.7902
Brugia malayi bZIP transcription factor family protein 0.009 0.0689 0.1085
Mycobacterium tuberculosis Probable reductase 0.0199 0.1701 0.2973
Brugia malayi nuclear hormone receptor 0.0022 0.0057 0.009
Loa Loa (eye worm) neuropeptide F receptor 0.0209 0.1793 0.304
Plasmodium vivax hypothetical protein, conserved 0.0044 0.0264 0.0441
Brugia malayi Blistered cuticle protein 3 0.0078 0.0577 0.0908
Schistosoma mansoni tyrosine kinase 0.0085 0.0643 0.0688
Toxoplasma gondii Erv1 / Alr family protein 0.0037 0.0197 0.0323
Brugia malayi Voltage-gated potassium channel, Shab-family (KCNB, Kv2-like) alpha-subunit 0.0038 0.0205 0.0322
Leishmania major C-8 sterol isomerase-like protein 0.0394 0.3507 0.457
Schistosoma mansoni glutamate receptor kainate 0.0173 0.1462 0.1574
Loa Loa (eye worm) hypothetical protein 0.0038 0.0205 0.0347
Loa Loa (eye worm) hypothetical protein 0.0259 0.2254 0.3822
Echinococcus multilocularis atrial natriuretic peptide receptor 0.0024 0.0083 0.0077
Mycobacterium ulcerans dehydrogenase 0.0088 0.0675 0.2181
Loa Loa (eye worm) Sodium:neurotransmitter symporter family protein 0.0044 0.0264 0.0447
Schistosoma mansoni cellular tumor antigen P53 0.0053 0.0347 0.0369
Loa Loa (eye worm) hypothetical protein 0.0033 0.0161 0.0272
Toxoplasma gondii Sodium:neurotransmitter symporter family protein 0.0044 0.0264 0.0441
Trichomonas vaginalis glucosylceramidase, putative 0.0191 0.1627 0.5535
Loa Loa (eye worm) hypothetical protein 0.0044 0.0264 0.0447
Toxoplasma gondii hypothetical protein 0.0038 0.0205 0.0337
Brugia malayi Phosphatidylinositol 3- and 4-kinase family protein 0.0016 0.0006 0.001
Trypanosoma cruzi NADH dehydrogenase, putative 0.0088 0.0675 0.0873
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0209 0.1793 0.1932
Trypanosoma cruzi C-8 sterol isomerase, putative 0.0394 0.3507 0.457
Schistosoma mansoni hyperpolarization activated cyclic nucleotide-gated potassium channel 0.0038 0.0205 0.0215
Loa Loa (eye worm) hypothetical protein 0.0209 0.1793 0.304
Echinococcus multilocularis epidermal growth factor receptor 0.0161 0.1346 0.134
Schistosoma mansoni vesicular amine transporter 0.0038 0.0205 0.0215
Giardia lamblia GTOR 0.0048 0.0302 0.0894
Echinococcus multilocularis voltage dependent L type calcium channel subunit 0.0138 0.1133 0.1128
Brugia malayi hypothetical protein 0.0209 0.1793 0.2822
Echinococcus multilocularis dihydropyrimidine dehydrogenase (NADP+) 0.0088 0.0675 0.0669
Echinococcus granulosus dihydropyrimidine dehydrogenase NADP 0.0088 0.0675 0.0669
Trypanosoma cruzi calmodulin 0.0026 0.01 0.0122
Echinococcus multilocularis fmrfamide receptor 0.0209 0.1793 0.1787
Schistosoma mansoni loxhd1 0.0042 0.0248 0.0261
Loa Loa (eye worm) hypothetical protein 0.0209 0.1793 0.304
Trichomonas vaginalis PIKK family atypical protein kinase 0.0026 0.0097 0.0331
Loa Loa (eye worm) melatonin receptor type 1A 0.0209 0.1793 0.304
Brugia malayi Voltage-gated calcium channel, alpha subunit 0.0038 0.0205 0.0322
Echinococcus granulosus jumonji domain containing protein 0.0043 0.0259 0.0253
Loa Loa (eye worm) hypothetical protein 0.0038 0.0205 0.0347
Brugia malayi Nuclear hormone receptor family member nhr-31 0.0022 0.0057 0.009
Schistosoma mansoni rab6-interacting 0.0042 0.0248 0.0261
Echinococcus multilocularis transfer RNA-Gly 0.0038 0.0205 0.0199
Loa Loa (eye worm) hypothetical protein 0.0209 0.1793 0.304
Loa Loa (eye worm) hypothetical protein 0.0038 0.0205 0.0347
Brugia malayi Inositol-1 0.004 0.0223 0.0351
Loa Loa (eye worm) hypothetical protein 0.0209 0.1793 0.304
Mycobacterium ulcerans endonuclease IV 0.0082 0.0617 0.198
Echinococcus granulosus calmodulin 0.0026 0.01 0.0093
Echinococcus multilocularis tyrosine protein kinase Fyn 0.0037 0.0202 0.0196
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0022 0.0057 0.009
Schistosoma mansoni growth hormone secretagogue receptor 0.0209 0.1793 0.1932
Echinococcus granulosus potassium voltage gated channel subfamily H 0.0046 0.0287 0.0281
Echinococcus multilocularis proto oncogene tyrosine protein kinase LCK 0.0041 0.0239 0.0232
Trichomonas vaginalis PIKK family atypical protein kinase 0.0026 0.0098 0.0332
Loa Loa (eye worm) cyclic-nucleotide gated cation channel 0.0043 0.0253 0.0429
Echinococcus granulosus potassium voltage gated channel protein 0.0038 0.0205 0.0199
Trichomonas vaginalis chromobox protein, putative 0.0075 0.0548 0.1863
Schistosoma mansoni cpg binding protein 0.0032 0.0158 0.0164
Leishmania major target of rapamycin kinase (TOR) kinase 3 0.0038 0.0212 0.0268
Loa Loa (eye worm) O-glycosyl hydrolase family 30 protein 0.0276 0.2417 0.4098
Echinococcus granulosus orexin receptor type 2 0.0209 0.1793 0.1787
Echinococcus granulosus lysine specific demethylase 5A 0.004 0.0223 0.0217
Echinococcus multilocularis lysine specific demethylase 5A 0.0038 0.0207 0.0201
Echinococcus multilocularis PHD finger protein rhinoceros 0.0031 0.0146 0.014
Trypanosoma cruzi calmodulin, putative 0.0026 0.01 0.0122
Echinococcus multilocularis FAD linked sulfhydryl oxidase ALR 0.0037 0.0197 0.0191
Brugia malayi aminoadipate-semialdehyde dehydrogenase-phosphopantetheinyl transferase 0.0089 0.0681 0.1072
Loa Loa (eye worm) adenylyl cyclase 3 0.0083 0.0629 0.1067
Echinococcus granulosus voltage dependent calcium channel 0.0138 0.1133 0.1128
Echinococcus granulosus cyclic nucleotide gated cation channel alpha 3 0.0043 0.0253 0.0247
Trichomonas vaginalis DNA topoisomerase II, putative 0.015 0.1242 0.4227
Schistosoma mansoni hypothetical protein 0.0017 0.0013 0.0008
Loa Loa (eye worm) hypothetical protein 0.0033 0.0159 0.0269
Trichomonas vaginalis dihydroorotate dehydrogenase, putative 0.0088 0.0675 0.2297
Trypanosoma cruzi ferric reductase transmembrane protein, putative 0.0036 0.0195 0.0246
Brugia malayi latrophilin 2 splice variant baaae 0.0036 0.0195 0.0306
Schistosoma mansoni biogenic amine receptor 0.0209 0.1793 0.1932
Trypanosoma brucei isocitrate dehydrogenase [NADP], mitochondrial precursor, putative 0.0017 0.0014 0.0009
Trichomonas vaginalis chromobox protein, putative 0.0045 0.0274 0.0931
Schistosoma mansoni voltage-gated potassium channel 0.0038 0.0205 0.0215
Schistosoma mansoni neuropeptide receptor 0.0209 0.1793 0.1932
Trypanosoma cruzi ferric reductase transmembrane protein, putative 0.0036 0.0195 0.0246
Plasmodium falciparum type II NADH:ubiquinone oxidoreductase 0.0088 0.0675 0.1166
Toxoplasma gondii DNA topoisomerase 2, putative 0.015 0.1242 0.2165
Loa Loa (eye worm) isocitrate dehydrogenase 0.0017 0.0014 0.0023
Echinococcus granulosus geminin 0.0181 0.1537 0.1531
Echinococcus multilocularis NADP dependent isocitrate dehydrogenase 0.0017 0.0014 0.0007
Leishmania major hypothetical protein, conserved 0.0088 0.0675 0.0873
Echinococcus multilocularis nmda type glutamate receptor 0.0199 0.1699 0.1694
Brugia malayi Large-conductance calcium-activated potassium channel Slo-1 (KCNMA) alpha subunit. C. elegans slo-1 ortholog 0.0038 0.0205 0.0322
Echinococcus granulosus hypothetical protein 0.0038 0.0205 0.0199
Echinococcus granulosus glutamate synthase 0.0088 0.0675 0.0669
Brugia malayi Sodium:neurotransmitter symporter family protein 0.0044 0.0264 0.0415
Mycobacterium tuberculosis Probable carbon monoxyde dehydrogenase (large chain) 0.0087 0.0667 0.1151
Echinococcus granulosus intermediate filament protein 0.0029 0.0124 0.0118
Echinococcus multilocularis glutamate (NMDA) receptor subunit 0.035 0.3103 0.3099
Echinococcus multilocularis peregrin 0.0031 0.0146 0.014
Loa Loa (eye worm) nuclear hormone receptor family member nhr-41 0.0022 0.0057 0.0097
Loa Loa (eye worm) hypothetical protein 0.0253 0.2201 0.3732
Mycobacterium tuberculosis Probable oxidoreductase 0.0444 0.3965 0.6963
Entamoeba histolytica tyrosyl-DNA phosphodiesterase, putative 0.0071 0.0511 0.1726
Treponema pallidum quinoline 2-oxidoreductase 0.0029 0.013 0.0298
Plasmodium falciparum transporter, putative 0.0044 0.0264 0.0441
Echinococcus multilocularis serotonin receptor 0.047 0.4207 0.4203
Echinococcus granulosus transcription factor Dp 1 0.0041 0.0236 0.0229
Brugia malayi DNA topoisomerase II, alpha isozyme 0.015 0.1242 0.1956
Schistosoma mansoni disulfide oxidoreductase 0.0088 0.0675 0.0723
Brugia malayi intermediate filament protein 0.0029 0.0124 0.0195
Loa Loa (eye worm) cytochrome P450 family protein 0.0021 0.0049 0.0083
Trypanosoma cruzi NADH dehydrogenase, putative 0.0088 0.0675 0.0873
Echinococcus multilocularis musashi 0.0029 0.0124 0.0118
Trypanosoma cruzi inositol 1,4,5-trisphosphate receptor, putative 0.0038 0.0205 0.0259
Loa Loa (eye worm) hypothetical protein 0.0209 0.1793 0.304
Schistosoma mansoni tyrosine kinase 0.0161 0.1346 0.1448
Trichomonas vaginalis glucosylceramidase, putative 0.0276 0.2417 0.8222
Schistosoma mansoni voltage-gated potassium channel 0.0041 0.0239 0.0251
Echinococcus multilocularis sulfide:quinone oxidoreductase 0.0088 0.0675 0.0669
Loa Loa (eye worm) gonadotropin-releasing hormone receptor 2 0.0209 0.1793 0.304
Echinococcus multilocularis transient receptor potential cation channel 0.0038 0.0205 0.0199
Trypanosoma cruzi pyridine nucleotide-disulphide oxidoreductase, putative 0.0088 0.0675 0.0873
Schistosoma mansoni sulfide quinone reductase 0.0088 0.0675 0.0723
Onchocerca volvulus 0.0209 0.1793 0.7902
Echinococcus multilocularis neuropeptide receptor 0.0209 0.1793 0.1787
Brugia malayi metabotropic glutamate receptor type 2 0.0024 0.0083 0.013
Brugia malayi Protein kinase domain containing protein 0.0052 0.034 0.0535
Loa Loa (eye worm) voltage-gated calcium channel 0.0038 0.0205 0.0347
Brugia malayi Pyridine nucleotide-disulphide oxidoreductase family protein 0.0088 0.0675 0.1063
Echinococcus granulosus shaker cognate 0.0038 0.0205 0.0199
Brugia malayi Cytochrome P450 family protein 0.0021 0.0049 0.0077
Schistosoma mansoni voltage-gated potassium channel 0.0038 0.0205 0.0215
Echinococcus multilocularis dro:myosuppressin receptor 0.0209 0.1793 0.1787
Echinococcus granulosus tyrosine protein kinase Blk 0.0037 0.0202 0.0196
Echinococcus granulosus tm gpcr rhodopsin 0.0763 0.6922 0.692
Loa Loa (eye worm) hypothetical protein 0.0083 0.0629 0.1067
Brugia malayi glutamate synthase 0.0088 0.0675 0.1063
Brugia malayi Pyridine nucleotide-disulphide oxidoreductase family protein 0.0088 0.0675 0.1063
Schistosoma mansoni protein kinase 0.003 0.0135 0.0139
Entamoeba histolytica fructose-1,6-bisphosphate aldolase, putative 0.0313 0.2754 1
Plasmodium falciparum calmodulin 0.0026 0.01 0.0152
Brugia malayi Cyclic-nucleotide gated cation channel 0.0043 0.0253 0.0398
Schistosoma mansoni hypothetical protein 0.0073 0.0533 0.057
Schistosoma mansoni tyrosine kinase 0.0085 0.0643 0.0688
Trypanosoma brucei ferric reductase transmembrane protein, putative 0.0036 0.0195 0.0246
Leishmania major calmodulin, putative 0.0026 0.01 0.0122
Schistosoma mansoni histone-lysine n-methyltransferase suv9 0.0045 0.0272 0.0287
Leishmania major acetoin dehydrogenase e3 component-like protein 0.0656 0.593 0.7734
Loa Loa (eye worm) hypothetical protein 0.0209 0.1793 0.304
Mycobacterium tuberculosis Probable membrane NADH dehydrogenase NdhA 0.0199 0.1701 0.2973
Onchocerca volvulus 0.0209 0.1793 0.7902
Brugia malayi Sodium:neurotransmitter symporter family protein 1, putative 0.0044 0.0264 0.0415
Mycobacterium tuberculosis Probable nitrite reductase [NAD(P)H] large subunit [FAD flavoprotein] NirB 0.0199 0.1701 0.2973
Echinococcus multilocularis glutamate receptor ionotropic kainate 0.0074 0.0543 0.0537
Echinococcus multilocularis uncharacterized sodium dependent transporter 0.0044 0.0264 0.0258
Brugia malayi Voltage-gated potassium channel, Shaw-family (KCNC, Kv3-like) alpha-subunit 0.0038 0.0205 0.0322
Wolbachia endosymbiont of Brugia malayi dihydrolipoamide dehydrogenase E3 component 0.0333 0.2939 1
Echinococcus multilocularis adenylate cyclase 9 0.0083 0.0629 0.0623
Mycobacterium tuberculosis Probable soluble pyridine nucleotide transhydrogenase SthA (STH) (NAD(P)(+) transhydrogenase [B-specific]) (nicotinamide nucleot 0.0333 0.2939 0.5155
Plasmodium vivax multidomain scavenger receptor, putative 0.0042 0.0248 0.0413
Echinococcus multilocularis rhodopsin orphan GPCR 0.0209 0.1793 0.1787
Mycobacterium leprae Probable NADH-dependent glutamate synthase (small subunit) GltD (L-glutamate synthase) (L-glutamate synthetase) (NADH-glutamate 0.0088 0.0675 0.1582
Echinococcus granulosus transient receptor potential cation channel 0.0038 0.0205 0.0199
Plasmodium falciparum ataxin-2 like protein, putative 0.0027 0.0107 0.0164
Loa Loa (eye worm) metabotropic glutamate receptor 8 0.0024 0.0083 0.014
Loa Loa (eye worm) jmjC domain-containing protein 0.004 0.0223 0.0378
Trichomonas vaginalis voltage and ligand gated potassium channel, putative 0.0018 0.0019 0.0066
Loa Loa (eye worm) hypothetical protein 0.0101 0.0795 0.1347
Echinococcus granulosus Glutamate receptor ionotropic kainate 2 0.0198 0.1688 0.1682
Echinococcus granulosus proto oncogene tyrosine protein kinase LCK 0.0041 0.0239 0.0232
Schistosoma mansoni coup transcription factor 0.0022 0.0057 0.0055
Leishmania major mitogen activated protein kinase 4, putative;with=GeneDB:LmxM19.1440 0.0055 0.0362 0.0464
Loa Loa (eye worm) hypothetical protein 0.0209 0.1793 0.304
Trichomonas vaginalis aldehyde oxidase, putative 0.0185 0.1574 0.5357
Loa Loa (eye worm) tyrosyl-DNA phosphodiesterase 0.0071 0.0511 0.0867
Echinococcus multilocularis apoptosis inducing factor 1 mitochondrial 0.0088 0.0675 0.0669
Brugia malayi Phosphatidylinositol 3- and 4-kinase family protein 0.0048 0.0302 0.0476
Brugia malayi Voltage-gated calcium channel, L-type, alpha subunit. C. elegans egl-19 ortholog 0.0138 0.1133 0.1784
Echinococcus granulosus chromobox protein 1 0.0075 0.0548 0.0541
Mycobacterium leprae PROBABLE ENDONUCLEASE IV END (ENDODEOXYRIBONUCLEASE IV) (APURINASE) 0.0082 0.0617 0.1433
Trichomonas vaginalis CMGC family protein kinase 0.0055 0.0362 0.1232
Echinococcus multilocularis CalModulin family member (cmd 1) 0.0026 0.01 0.0093
Trichomonas vaginalis ap endonuclease, putative 0.002 0.0043 0.0148
Brugia malayi Latrophilin receptor protein 2 0.0017 0.0013 0.0021
Schistosoma mansoni intermediate filament proteins 0.0029 0.0124 0.0128
Schistosoma mansoni photoreceptor-specific nuclear receptor related 0.0022 0.0057 0.0055
Leishmania major apurinic/apyrimidinic endonuclease-redox protein 0.002 0.0043 0.0048
Echinococcus multilocularis thyroid hormone receptor alpha 0.0022 0.0057 0.0051
Echinococcus multilocularis Glutamate receptor, ionotropic kainate 2 0.0198 0.1688 0.1682
Echinococcus multilocularis transient receptor potential cation channel 0.0038 0.0208 0.0201
Entamoeba histolytica hypothetical protein 0.0024 0.0083 0.0146
Echinococcus granulosus voltage dependent calcium channel 0.0057 0.038 0.0374
Loa Loa (eye worm) hypothetical protein 0.0038 0.0205 0.0347
Mycobacterium leprae Probable NADPH:adrenodoxin oxidoreductase FprA (NADPH-FERREDOXIN REDUCTASE) 0.0088 0.0675 0.1582
Echinococcus granulosus g protein linked acetylcholine receptor gar 2a 0.0209 0.1793 0.1787
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0209 0.1793 0.1932
Echinococcus granulosus sodium:chloride dependent neurotransmitter 0.0044 0.0264 0.0258
Loa Loa (eye worm) 5-hydroxytryptamine 2C receptor 0.0209 0.1793 0.304
Wolbachia endosymbiont of Brugia malayi dihydrolipoamide dehydrogenase E3 component 0.0333 0.2939 1
Loa Loa (eye worm) hypothetical protein 0.0029 0.0124 0.021
Trypanosoma cruzi mitochondrial DNA topoisomerase II, putative 0.0168 0.1412 0.1835
Trichomonas vaginalis PIKK family atypical protein kinase 0.0048 0.0302 0.1029
Trichomonas vaginalis disulfide oxidoreductase, putative 0.0088 0.0675 0.2297
Echinococcus multilocularis sodium:chloride dependent neurotransmitter 0.0044 0.0264 0.0258
Schistosoma mansoni histamine h1 receptor 0.0209 0.1793 0.1932
Schistosoma mansoni myosin xvIII 0.0209 0.1793 0.1932
Trichomonas vaginalis glucosylceramidase, putative 0.0181 0.1537 0.5228
Echinococcus multilocularis COUP TF:Svp nuclear hormone receptor 0.0022 0.0057 0.0051
Echinococcus multilocularis geminin 0.0181 0.1537 0.1531
Trichomonas vaginalis PIKK family atypical protein kinase 0.0026 0.0098 0.0332
Loa Loa (eye worm) cytochrome P450 family protein 0.0021 0.0049 0.0083
Plasmodium falciparum AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.002 0.0043 0.0053
Plasmodium vivax DNA topoisomerase II, putative 0.015 0.1242 0.2165
Onchocerca volvulus 0.0209 0.1793 0.7902
Trypanosoma brucei FAT domain/Rapamycin binding domain/Phosphatidylinositol 3- and 4-kinase, putative 0.002 0.0042 0.0047
Loa Loa (eye worm) hypothetical protein 0.0044 0.0264 0.0447
Mycobacterium ulcerans DNA gyrase subunit B 0.0087 0.0665 0.2146
Chlamydia trachomatis arginine ABC transporter substrate-binding protein ArtJ 0.004 0.0232 0.0501
Echinococcus multilocularis sex peptide receptor 0.0209 0.1793 0.1787
Echinococcus granulosus transient receptor potential gamma protein 0.0038 0.0205 0.0199
Echinococcus granulosus biogenic amine 5HT receptor 0.047 0.4207 0.4203
Echinococcus multilocularis G protein coupled receptor 139 0.0209 0.1793 0.1787
Brugia malayi Dopamine receptor protein 1, putative (partial) 0.0209 0.1793 0.2822
Loa Loa (eye worm) hypothetical protein 0.0525 0.4724 0.8011
Echinococcus granulosus insulin receptor 0.0052 0.034 0.0334
Mycobacterium ulcerans NADH dehydrogenase Ndh 0.0088 0.0675 0.2181
Loa Loa (eye worm) hypothetical protein 0.0022 0.0057 0.0097
Leishmania major hypothetical protein, unknown function 0.0038 0.0205 0.0259
Loa Loa (eye worm) hypothetical protein 0.0209 0.1793 0.304
Brugia malayi AKH receptor 0.0209 0.1793 0.2822
Echinococcus granulosus survival motor neuron protein 1 0.0253 0.2201 0.2196
Loa Loa (eye worm) hypothetical protein 0.0022 0.0057 0.0097
Onchocerca volvulus 0.0209 0.1793 0.7902
Echinococcus multilocularis tyrosine kinase 0.0026 0.0102 0.0095
Treponema pallidum NADH oxidase 0.0333 0.2939 1
Schistosoma mansoni jumonji domain containing protein 0.0081 0.0609 0.0652
Schistosoma mansoni hyperpolarization activated cyclic nucleotide-gated potassium channel 0.0043 0.0253 0.0267
Trichomonas vaginalis dihydroorotate dehydrogenase, putative 0.0088 0.0675 0.2297
Chlamydia trachomatis glutamine binding protein 0.004 0.0232 0.0501
Echinococcus multilocularis sodium and chloride dependent glycine 0.0044 0.0264 0.0258
Plasmodium falciparum DNA topoisomerase 2 0.015 0.1242 0.2165
Trichomonas vaginalis PIKK family atypical protein kinase 0.0036 0.0188 0.0641
Loa Loa (eye worm) hypothetical protein 0.0042 0.0248 0.042
Echinococcus granulosus dnaJ subfamily B 0.0438 0.3911 0.3907
Mycobacterium tuberculosis Possible dehydrogenase/reductase 0.0088 0.0675 0.1166
Mycobacterium ulcerans NADH dehydrogenase Ndh1 0.0088 0.0675 0.2181
Schistosoma mansoni glutamate synthase 0.0088 0.0675 0.0723
Loa Loa (eye worm) serotonin transporter b 0.0259 0.2254 0.3822
Loa Loa (eye worm) hypothetical protein 0.0259 0.2254 0.3822
Trypanosoma cruzi mitogen activated protein kinase 4, putative 0.0055 0.0362 0.0464
Onchocerca volvulus Dopamine\/Ecdysteroid receptor homolog 0.0209 0.1793 0.7902
Echinococcus multilocularis voltage gated potassium channel 0.0038 0.0205 0.0199
Brugia malayi ERG2 and Sigma1 receptor like protein 0.0394 0.3507 0.552
Echinococcus multilocularis NADPH:adrenodoxin oxidoreductase 0.0088 0.0675 0.0669
Onchocerca volvulus 0.0209 0.1793 0.7902
Schistosoma mansoni NADP-specific isocitrate dehydrogenase 0.0017 0.0014 0.0008
Schistosoma mansoni FTZ-F1 nuclear receptor-like protein 0.0022 0.0057 0.0055
Loa Loa (eye worm) hypothetical protein 0.0042 0.0248 0.042
Brugia malayi Serotonin receptor 0.0209 0.1793 0.2822
Echinococcus granulosus metabotropic glutamate receptor 2 0.0024 0.0083 0.0077
Schistosoma mansoni opsin-like receptor 0.0209 0.1793 0.1932
Loa Loa (eye worm) hypothetical protein 0.0038 0.0205 0.0347
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0022 0.0057 0.0051
Trypanosoma cruzi dihydrolipoyl dehydrogenase, putative 0.0333 0.2939 0.3829
Echinococcus granulosus rhodopsin orphan GPCR 0.0209 0.1793 0.1787
Trypanosoma brucei PAB1-binding protein , putative 0.0027 0.0107 0.0131
Loa Loa (eye worm) metabotropic GABA-B receptor subtype 2 0.0024 0.0083 0.014
Trypanosoma brucei cytochrome P450, putative 0.0021 0.0049 0.0056
Brugia malayi Cytochrome P450 family protein 0.0021 0.0049 0.0077
Trichomonas vaginalis dihydrolipoamide dehydrogenase, putative 0.0088 0.0675 0.2297
Schistosoma mansoni amine GPCR 0.0209 0.1793 0.1932
Leishmania major dihydrolipoamide dehydrogenase, putative 0.0333 0.2939 0.3829
Schistosoma mansoni ryanodine receptor related 0.0038 0.0205 0.0215
Echinococcus granulosus Glutamate receptor ionotropic kainate 2 0.0198 0.1688 0.1682
Loa Loa (eye worm) hypothetical protein 0.0024 0.0083 0.014
Loa Loa (eye worm) hypothetical protein 0.047 0.4207 0.7134
Schistosoma mansoni microtubule-associated protein tau 0.0738 0.6697 0.7235
Echinococcus multilocularis g protein coupled receptor 0.0209 0.1793 0.1787
Echinococcus granulosus voltage dependent calcium channel type d subunit|voltage dependent calcium channel|voltage dependent L type calcium channel subu 0.0138 0.1133 0.1128
Echinococcus multilocularis calcium activated potassium channel 0.0038 0.021 0.0203
Echinococcus multilocularis potassium voltage gated channel subfamily KQT 0.0038 0.0205 0.0199
Loa Loa (eye worm) ion channel NompC 0.0038 0.0205 0.0347
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0731 0.6626 0.8642
Loa Loa (eye worm) hypothetical protein 0.0209 0.1793 0.304
Brugia malayi G protein-coupled receptor 0.0209 0.1793 0.2822
Schistosoma mansoni voltage-dependent calcium channel 0.0038 0.0205 0.0215
Schistosoma mansoni histamine-responsive GPCR (AAF21638) 0.0209 0.1793 0.1932
Brugia malayi CXXC zinc finger family protein 0.0031 0.0142 0.0223
Brugia malayi Dopamine receptor protein 2 0.0209 0.1793 0.2822
Trichomonas vaginalis CMGC family protein kinase 0.0055 0.0362 0.1232
Schistosoma mansoni amine GPCR 0.0209 0.1793 0.1932
Loa Loa (eye worm) hypothetical protein 0.0038 0.0205 0.0347
Echinococcus granulosus RUN 0.0042 0.0248 0.0242
Loa Loa (eye worm) glutamate receptor 2 0.0173 0.1462 0.2479
Loa Loa (eye worm) hypothetical protein 0.0038 0.0205 0.0347
Plasmodium vivax apurinic/apyrimidinic endonuclease Apn1, putative 0.0082 0.0617 0.1063
Echinococcus multilocularis FTZ F1 alpha 0.0022 0.0057 0.0051
Trichomonas vaginalis PIKK family atypical protein kinase 0.0032 0.0156 0.053
Schistosoma mansoni bromodomain-containing nuclear protein 1 brd1 0.0031 0.0146 0.0151
Loa Loa (eye worm) hypothetical protein 0.0089 0.0681 0.1155
Echinococcus granulosus transient receptor potential cation channel 0.0038 0.0208 0.0201
Schistosoma mansoni hypothetical protein 0.0088 0.0675 0.0723
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0313 0.2754 0.9369
Trichomonas vaginalis PIKK family atypical protein kinase 0.0031 0.0146 0.0498
Trichomonas vaginalis voltage and ligand gated potassium channel, putative 0.0049 0.0313 0.1064
Trypanosoma cruzi mitogen-activated protein kinase 11, putative 0.0055 0.0362 0.0464
Echinococcus multilocularis chromobox protein 1 0.0075 0.0548 0.0541
Trypanosoma cruzi myo-inositol-1(or 4)-monophosphatase 1, putative 0.004 0.0223 0.0283
Loa Loa (eye worm) hypothetical protein 0.0022 0.0057 0.0096
Echinococcus granulosus neuropeptide receptor 0.0209 0.1793 0.1787
Brugia malayi Glutamate receptor 2 precursor 0.0173 0.1462 0.2301
Echinococcus granulosus hyperpolarization activated cyclic 0.0043 0.0253 0.0247
Echinococcus multilocularis jumonji domain containing protein 0.0043 0.0259 0.0253
Trichomonas vaginalis PIKK family atypical protein kinase 0.0041 0.0237 0.0808
Plasmodium falciparum phd finger protein, putative 0.0031 0.0146 0.0233
Echinococcus granulosus g protein linked acetylcholine receptor gar 2a 0.0209 0.1793 0.1787
Echinococcus multilocularis potassium voltage gated channel subfamily H 0.0046 0.0287 0.0281
Loa Loa (eye worm) nuclear hormone receptor family member nhr-49 0.0022 0.0057 0.0097
Onchocerca volvulus Heterochromatin protein 1 homolog 0.0042 0.0244 0.0853
Chlamydia trachomatis Ssodium-dependent amino acid transporter 0.0044 0.0264 0.0614
Echinococcus multilocularis calmodulin 0.0026 0.01 0.0093
Echinococcus granulosus FTZ F1 nuclear receptor protein 0.0022 0.0057 0.0051
Schistosoma mansoni inositol monophosphatase 0.004 0.0223 0.0234
Schistosoma mansoni muscarinic acetylcholine (GAR) receptor 0.0209 0.1793 0.1932
Loa Loa (eye worm) nuclear Hormone Receptor family member 0.0022 0.0057 0.0097
Loa Loa (eye worm) pyridine nucleotide-disufhide oxidoreductase 0.0088 0.0675 0.1145
Trichomonas vaginalis disulfide oxidoreductase, putative 0.0088 0.0675 0.2297
Brugia malayi ecdysteroid receptor 0.0022 0.0057 0.009
Plasmodium falciparum DNA gyrase subunit B 0.0087 0.0665 0.1148
Loa Loa (eye worm) pre-SET domain-containing protein family protein 0.0223 0.1926 0.3266
Schistosoma mansoni cyclic-nucleotide-gated cation channel 0.0038 0.0205 0.0215
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0019 0.0035 0.0118
Echinococcus multilocularis two pore calcium channel protein 2 0.0038 0.0205 0.0199
Mycobacterium tuberculosis Probable carbon monoxyde dehydrogenase (small chain) 0.0035 0.0185 0.0302
Schistosoma mansoni tyrosine kinase 0.0041 0.0239 0.0251
Schistosoma mansoni norepinephrine/norepinephrine transporter 0.0044 0.0264 0.0278
Brugia malayi dihydrolipoyl dehydrogenase, mitochondrial precursor, putative 0.0333 0.2939 0.4627
Loa Loa (eye worm) hypothetical protein 0.0022 0.0057 0.0097
Echinococcus granulosus glutamate receptor 2 0.0124 0.1002 0.0996
Brugia malayi Sodium:neurotransmitter symporter family protein 0.0044 0.0264 0.0415
Trypanosoma brucei ERV/ALR sulfhydryl oxidase domain-containing protein 0.0037 0.0197 0.0249
Loa Loa (eye worm) hypothetical protein 0.0021 0.0047 0.008
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0209 0.1793 0.1932
Echinococcus multilocularis rhodopsin orphan GPCR 0.0209 0.1793 0.1787
Echinococcus granulosus 5'partial|histone lysine N methyltransferase SETDB2 0.0031 0.0142 0.0136
Loa Loa (eye worm) hypothetical protein 0.0053 0.0351 0.0595
Loa Loa (eye worm) hypothetical protein 0.0259 0.2254 0.3822
Echinococcus granulosus lipoxygenase domain containing protein 0.0042 0.0248 0.0242
Schistosoma mansoni hypothetical protein 0.0042 0.0248 0.0261
Schistosoma mansoni alpha-1 adrenergic receptor 0.0209 0.1793 0.1932
Trypanosoma brucei DNA topoisomerase II beta, putative 0.0141 0.1168 0.1516
Echinococcus granulosus uncharacterized sodium dependent transporter 0.0044 0.0264 0.0258
Echinococcus multilocularis neuropeptide FF receptor 2 0.0209 0.1793 0.1787
Loa Loa (eye worm) voltage-gated potassium channel 0.0038 0.0205 0.0347
Loa Loa (eye worm) hypothetical protein 0.0209 0.1793 0.304
Wolbachia endosymbiont of Brugia malayi 4'-phosphopantetheinyl transferase 0.0025 0.0089 0.0157
Schistosoma mansoni peptide (allatostatin/somatostatin)-like receptor 0.0209 0.1793 0.1932
Schistosoma mansoni sodium-dependent neurotransmitter transporter 0.0044 0.0264 0.0278
Schistosoma mansoni voltage-gated ion channel 0.0038 0.0205 0.0215
Loa Loa (eye worm) hypothetical protein 0.0209 0.1793 0.304
Trichomonas vaginalis CMGC family protein kinase 0.0055 0.0362 0.1232
Onchocerca volvulus Bile acid receptor homolog 0.0022 0.0057 0.0003
Echinococcus granulosus voltage gated potassium channel 0.0046 0.0287 0.0281
Trypanosoma cruzi calmodulin, putative 0.0026 0.01 0.0122
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0209 0.1793 0.1932
Trichomonas vaginalis PIKK family atypical protein kinase 0.0038 0.0211 0.0719
Trichomonas vaginalis glucosylceramidase, putative 0.0181 0.1537 0.5228
Loa Loa (eye worm) hypothetical protein 0.0209 0.1793 0.304
Giardia lamblia Glutamate synthase 0.0088 0.0675 0.2181
Echinococcus multilocularis sodium leak channel non selective protein 0.0038 0.0205 0.0199
Trichomonas vaginalis inositol monophosphatase, putative 0.004 0.0223 0.0759
Schistosoma mansoni neuropeptide f receptor 76f 0.0209 0.1793 0.1932
Brugia malayi GnHR receptor homolog 0.0209 0.1793 0.2822
Echinococcus granulosus glutamate receptor subunit protein glur 0.0074 0.0543 0.0537
Treponema pallidum amino acid ABC transporter, periplasmic binding protein 0.004 0.0232 0.065
Loa Loa (eye worm) hypothetical protein 0.0209 0.1793 0.304
Loa Loa (eye worm) hypothetical protein 0.0028 0.0119 0.0202
Toxoplasma gondii target of rapamycin (TOR), putative 0.0036 0.0188 0.0308
Mycobacterium ulcerans dihydrolipoamide dehydrogenase 0.0333 0.2939 1
Onchocerca volvulus 0.0033 0.0161 0.0472
Onchocerca volvulus 0.0083 0.0629 0.2606
Loa Loa (eye worm) hypothetical protein 0.0036 0.0195 0.033
Trichomonas vaginalis PIKK family atypical protein kinase 0.0016 0.0006 0.0022
Echinococcus multilocularis serotonin transporter 0.0259 0.2254 0.2249
Trypanosoma brucei 2,4-dienoyl-coa reductase-like protein 0.0088 0.0675 0.0873
Brugia malayi Melatonin receptor type 1A 0.0209 0.1793 0.2822
Loa Loa (eye worm) blistered cuticle protein 3 0.0078 0.0577 0.0979
Trypanosoma cruzi hypothetical protein, conserved 0.0088 0.0675 0.0873
Echinococcus granulosus Potassium voltage gated channel protein Shaw 0.0038 0.0205 0.0199
Echinococcus multilocularis neuropeptide receptor A26 0.0701 0.6352 0.635
Echinococcus multilocularis glutamate receptor 2 0.0124 0.1002 0.0996
Trypanosoma cruzi myo-inositol-1(or 4)-monophosphatase 1, putative 0.004 0.0223 0.0283
Trypanosoma cruzi 2,4-dienoyl-coa reductase-like protein, putative 0.0088 0.0675 0.0873
Echinococcus multilocularis potassium large conductance calcium activated 0.0038 0.0205 0.0199
Echinococcus granulosus rhodopsin orphan GPCR 0.0209 0.1793 0.1787
Brugia malayi olfactory channel protein osm-9 0.0038 0.0208 0.0326
Onchocerca volvulus Adenylate cyclase type 2 homolog 0.0083 0.0629 0.2606
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0209 0.1793 0.1932
Echinococcus multilocularis neuropeptides capa receptor 0.0209 0.1793 0.1787
Echinococcus multilocularis neuropeptide Y receptor 0.0209 0.1793 0.1787
Echinococcus multilocularis biogenic amine (5HT) receptor 0.1015 0.9254 0.9253
Echinococcus granulosus sodium dependent neurotransmitter transporter 0.0044 0.0264 0.0258
Echinococcus granulosus atrial natriuretic peptide receptor 0.0024 0.0083 0.0077
Mycobacterium ulcerans ferredoxin reductase 0.0088 0.0675 0.2181
Schistosoma mansoni voltage-gated potassium channel 0.0038 0.0205 0.0215
Brugia malayi calmodulin 0.0026 0.01 0.0157
Toxoplasma gondii PHD-finger domain-containing protein 0.0031 0.0146 0.0233
Loa Loa (eye worm) hypothetical protein 0.0044 0.0264 0.0447
Echinococcus granulosus TRP transient receptor potential channel 0.0038 0.0205 0.0199
Echinococcus granulosus potassium channel KvQLT family member kqt 1 0.0038 0.0205 0.0199
Echinococcus multilocularis dnaJ subfamily B 0.0438 0.3911 0.3907
Echinococcus multilocularis tyrosine protein kinase Fgr 0.0041 0.0239 0.0232
Brugia malayi Nuclear hormone receptor family member nhr-14 0.0022 0.0057 0.009
Schistosoma mansoni jumonji/arid domain-containing protein 0.004 0.0223 0.0234
Brugia malayi hypothetical protein 0.0017 0.0018 0.0028
Brugia malayi Hypothetical 29.7 kDa protein C05D11.5 in chromosome III 0.0022 0.0057 0.0089
Loa Loa (eye worm) hypothetical protein 0.0046 0.0287 0.0486
Echinococcus multilocularis potassium voltage gated channel protein 0.0038 0.0205 0.0199
Schistosoma mansoni hyperpolarization activated cyclic nucleotide-gated potassium channel 0.0043 0.0253 0.0267
Echinococcus multilocularis mitogen activated protein kinase 3 0.0055 0.0362 0.0356
Echinococcus granulosus chromobox protein 1 0.0075 0.0548 0.0541
Brugia malayi Voltage-gated calcium channel, P/Q-type, alpha subunit. C. elegans unc-2 ortholog 0.0038 0.0205 0.0322
Echinococcus multilocularis lamin 0.0029 0.0124 0.0118
Echinococcus granulosus lamin dm0 0.0029 0.0124 0.0118
Echinococcus multilocularis Ribosomal protein S1, RNA binding domain 0.0074 0.0543 0.0537
Echinococcus granulosus transient receptor potential cation channel 0.0038 0.0205 0.0199
Trypanosoma cruzi target of rapamycin kinase 3 0.0038 0.0212 0.0268
Trichomonas vaginalis PIKK family atypical protein kinase 0.0036 0.0188 0.0641
Plasmodium falciparum DNA gyrase subunit A 0.0032 0.0155 0.0249
Echinococcus multilocularis rhodopsin orphan GPCR 0.0209 0.1793 0.1787
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0313 0.2754 0.9369
Schistosoma mansoni amine GPCR 0.0209 0.1793 0.1932
Trichomonas vaginalis PIKK family atypical protein kinase 0.0048 0.0302 0.1029
Mycobacterium leprae THIOREDOXIN TRXC (TRX) (MPT46) 0.0088 0.0675 0.1582
Plasmodium vivax dihydrolipoyl dehydrogenase, apicoplast, putative 0.0333 0.2939 0.5155
Trichomonas vaginalis glucosylceramidase, putative 0.0181 0.1537 0.5228
Brugia malayi Calcitonin receptor-like protein seb-1 0.0053 0.0351 0.0552
Echinococcus multilocularis dihydropyrimidine dehydrogenase (NADP+) 0.0088 0.0675 0.0669
Echinococcus multilocularis voltage dependent L type calcium channel subunit 0.0138 0.1133 0.1128
Schistosoma mansoni hypothetical protein 0.0052 0.0335 0.0355
Echinococcus granulosus short transient receptor potential channel 6 0.0038 0.0205 0.0199
Loa Loa (eye worm) hypothetical protein 0.0209 0.1793 0.304
Brugia malayi larval opioid receptor 0.0209 0.1793 0.2822
Schistosoma mansoni glutamate synthase 0.0088 0.0675 0.0723
Chlamydia trachomatis DNA gyrase subunit B 0.0069 0.0495 0.1426
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0022 0.0057 0.009
Brugia malayi hypothetical protein 0.0209 0.1793 0.2822
Echinococcus multilocularis NMDA receptor 0.0074 0.0543 0.0537
Echinococcus multilocularis neuropeptide s receptor 0.0701 0.6352 0.635
Trypanosoma cruzi PAB1-binding protein , putative 0.0027 0.0107 0.0131
Echinococcus granulosus tyrosine protein kinase HCK 0.0033 0.0165 0.0159
Loa Loa (eye worm) neuropeptide F receptor 0.0209 0.1793 0.304
Trichomonas vaginalis CMGC family protein kinase 0.0055 0.0362 0.1232
Loa Loa (eye worm) hypothetical protein 0.0038 0.0205 0.0347
Echinococcus granulosus FTZ F1 alpha 0.0022 0.0057 0.0051
Schistosoma mansoni tyrosine kinase 0.0052 0.034 0.0361
Echinococcus granulosus arachidonate 5 lipoxygenase 0.0185 0.1573 0.1568
Brugia malayi SRC-1 0.0041 0.0239 0.0375
Loa Loa (eye worm) norepinephrine transporter 0.0259 0.2254 0.3822
Echinococcus granulosus transient receptor potential cation channel 0.0038 0.0205 0.0199
Echinococcus granulosus rhodopsin orphan GPCR 0.0209 0.1793 0.1787
Brugia malayi hypothetical protein 0.0209 0.1793 0.2822
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0763 0.6922 0.692
Echinococcus granulosus L aminoadipate semialdehyde 0.0089 0.0681 0.0675
Schistosoma mansoni metabotropic glutamate receptor 0.0024 0.0083 0.0083
Echinococcus granulosus hyperpolarization activated cyclic 0.0043 0.0253 0.0247
Echinococcus granulosus Nuclear hormone receptor family member nhr 41 0.0022 0.0057 0.0051
Brugia malayi O-Glycosyl hydrolase family 30 protein 0.0276 0.2417 0.3804
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0016 0.0005 0.0016
Trypanosoma cruzi trypanothione reductase, putative 0.063 0.5689 0.7419
Mycobacterium tuberculosis NADPH:adrenodoxin oxidoreductase FprA (NADPH-ferredoxin reductase) 0.0088 0.0675 0.1166
Onchocerca volvulus Atrial natriuretic peptide receptor 3 homolog 0.003 0.0135 0.0354
Schistosoma mansoni two-pore calcium channel 0.0038 0.0205 0.0215
Leishmania major calcium channel protein, putative,ion transporter, putative 0.0456 0.4077 0.5315
Trypanosoma brucei dihydrolipoyl dehydrogenase 0.0333 0.2939 0.3829
Brugia malayi Probable DNA topoisomerase II 0.015 0.1242 0.1956
Schistosoma mansoni peptide (FMRFamide/somatostatin)-like receptor 0.0209 0.1793 0.1932
Schistosoma mansoni biogenic amine receptor 0.0209 0.1793 0.1932
Trypanosoma brucei phosphatidylinositol 4-kinase, putative 0.0048 0.0302 0.0387
Echinococcus granulosus voltage gated hydrogen channel 1 0.0038 0.0205 0.0199
Loa Loa (eye worm) hypothetical protein 0.0209 0.1793 0.304
Plasmodium vivax DNA gyrase subunit B, putative 0.0087 0.0665 0.1148
Schistosoma mansoni transient receptor potential cation channel subfamily m member 0.0038 0.0205 0.0215
Schistosoma mansoni hypothetical protein 0.0209 0.1793 0.1932
Loa Loa (eye worm) RGC/RGC protein kinase 0.003 0.0135 0.0228
Brugia malayi metabotropic GABA-B receptor subtype 2 0.0024 0.0083 0.013
Loa Loa (eye worm) hypothetical protein 0.0022 0.0057 0.0097
Schistosoma mansoni sodium/chloride dependent transporter 0.0044 0.0268 0.0283
Schistosoma mansoni hypothetical protein 0.0209 0.1793 0.1932
Mycobacterium leprae PROBABLE NADH DEHYDROGENASE NDH 0.0199 0.1701 0.4207
Schistosoma mansoni hypothetical protein 0.0036 0.0195 0.0204
Echinococcus multilocularis neuropeptide receptor 0.0209 0.1793 0.1787
Toxoplasma gondii DNA gyrase/topoisomerase IV, A subunit domain-containing protein 0.0032 0.0155 0.0249
Loa Loa (eye worm) hypothetical protein 0.0209 0.1793 0.304
Schistosoma mansoni lamin 0.0029 0.0124 0.0128
Loa Loa (eye worm) intermediate filament tail domain-containing protein 0.0029 0.0124 0.021
Schistosoma mansoni sodium-dependent neurotransmitter transporter 0.0044 0.0264 0.0278
Brugia malayi Voltage-gated potassium channel, Shaker-family (KCNA, Kv1-like) alpha-subunit 0.0038 0.0205 0.0322
Schistosoma mansoni inositol 145-trisphosphate receptor 0.0038 0.0205 0.0215
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0209 0.1793 0.1932
Loa Loa (eye worm) hypothetical protein 0.0652 0.5896 1
Brugia malayi Receptor family ligand binding region containing protein 0.0024 0.0083 0.013
Brugia malayi Adenylyl cyclase protein 0.0083 0.0629 0.099
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0209 0.1793 0.1932
Loa Loa (eye worm) hypothetical protein 0.0209 0.1793 0.304
Treponema pallidum hypothetical protein 0.003 0.0136 0.032
Mycobacterium ulcerans carbon monoxide dehydrogenase 0.0123 0.0995 0.3285
Echinococcus granulosus neuropeptide s receptor 0.0701 0.6352 0.635
Loa Loa (eye worm) hypothetical protein 0.0209 0.1793 0.304
Toxoplasma gondii pyridine nucleotide-disulfide oxidoreductase domain-containing protein 0.0088 0.0675 0.1166
Loa Loa (eye worm) hypothetical protein 0.0088 0.0675 0.1145
Loa Loa (eye worm) hypothetical protein 0.0042 0.0244 0.0414
Brugia malayi neuropeptide F receptor 0.0209 0.1793 0.2822
Brugia malayi PHD-finger family protein 0.0031 0.0146 0.0229
Schistosoma mansoni lamin 0.0029 0.0124 0.0128
Schistosoma mansoni tyrosine kinase 0.0026 0.0102 0.0103
Entamoeba histolytica fructose-1,6-bisphosphate aldolase, putative 0.0313 0.2754 1
Brugia malayi Intermediate filament tail domain containing protein 0.0029 0.0124 0.0195
Trypanosoma brucei inositol 1,4,5-trisphosphate receptor 0.0038 0.0205 0.0259
Schistosoma mansoni hypothetical protein 0.0209 0.1793 0.1932
Onchocerca volvulus Glucosylceramidase homolog 0.0181 0.1537 0.6736
Schistosoma mansoni sodium-dependent neurotransmitter transporter 0.0044 0.0264 0.0278
Loa Loa (eye worm) glutamate receptor 1 0.0173 0.1462 0.2479
Plasmodium vivax type II NADH:ubiquinone oxidoreductase, putative 0.0088 0.0675 0.1166
Brugia malayi Nuclear hormone receptor family member nhr-49 0.0022 0.0057 0.009
Trypanosoma cruzi ERV/ALR sulfhydryl oxidase domain-containing protein 0.0037 0.0197 0.0249
Mycobacterium ulcerans dihydrolipoamide dehydrogenase, LpdB 0.0333 0.2939 1
Loa Loa (eye worm) hypothetical protein 0.0027 0.0107 0.0181
Brugia malayi RE15519p 0.0209 0.1793 0.2822
Schistosoma mansoni voltage-gated potassium channel KCNQ 0.0038 0.0205 0.0215
Toxoplasma gondii CMGC kinase, MAPK family (ERK) MAPK-1 0.0055 0.0362 0.0614
Echinococcus multilocularis somatostatin receptor 0.0209 0.1793 0.1787
Brugia malayi Corticotropin releasing factor receptor 2 precursor, putative 0.0053 0.0351 0.0552
Echinococcus multilocularis short transient receptor potential channel 6 0.0038 0.0205 0.0199
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0209 0.1793 0.1932
Echinococcus granulosus glutamate receptor ionotropic kainate 0.0074 0.0543 0.0537
Trichomonas vaginalis glucosylceramidase, putative 0.0276 0.2417 0.8222
Entamoeba histolytica NAD(FAD)-dependent dehydrogenase, putative 0.0088 0.0675 0.2331
Echinococcus granulosus transient receptor potential cation channel 0.0038 0.0205 0.0199
Echinococcus multilocularis Glutamate receptor, ionotropic kainate 2 0.0198 0.1688 0.1682
Trichomonas vaginalis PIKK family atypical protein kinase 0.0016 0.0006 0.0022
Toxoplasma gondii transporter, cation channel family protein 0.0057 0.038 0.0646
Brugia malayi Sodium:neurotransmitter symporter family protein 0.0259 0.2254 0.3547
Echinococcus multilocularis sodium channel protein 0.0497 0.4457 0.4453
Entamoeba histolytica thioredoxin reductase, putative 0.0088 0.0675 0.2331
Trichomonas vaginalis voltage and ligand gated potassium channel, putative 0.0018 0.0019 0.0066
Schistosoma mansoni glutamate receptor NMDA 0.035 0.3103 0.3349
Leishmania major mitochondrial DNA topoisomerase II 0.0168 0.1412 0.1835
Loa Loa (eye worm) hypothetical protein 0.0209 0.1793 0.304
Echinococcus multilocularis peptide (allatostatin:somatostatin) 0.0209 0.1793 0.1787
Echinococcus granulosus CalModulin family member cmd 1 0.0026 0.01 0.0093
Loa Loa (eye worm) phosphatidylinositol 3 0.0048 0.0302 0.0513
Schistosoma mansoni dihydrolipoamide dehydrogenase 0.0333 0.2939 0.3171
Brugia malayi follicle stimulating hormone receptor 0.0209 0.1793 0.2822
Echinococcus granulosus potassium voltage gated channel subfamily H 0.0074 0.0547 0.054
Brugia malayi Voltage-gated potassium channel, KCNQ (Kv7-like) alpha-subunit. C. elegans kqt-1 ortholog 0.0038 0.0205 0.0322
Brugia malayi MAP kinase sur-1 0.0055 0.0362 0.057
Loa Loa (eye worm) hypothetical protein 0.0038 0.0205 0.0347
Toxoplasma gondii endonuclease IV APN 0.0082 0.0617 0.1063
Echinococcus granulosus sodium and chloride dependent glycine 0.0044 0.0264 0.0258
Onchocerca volvulus 0.0024 0.0083 0.0119
Echinococcus granulosus g protein coupled receptor 0.0209 0.1793 0.1787
Trichomonas vaginalis PIKK family atypical protein kinase 0.0029 0.0123 0.0419
Onchocerca volvulus 0.0052 0.0335 0.1267
Loa Loa (eye worm) RGC/RGC protein kinase 0.003 0.0135 0.0228
Schistosoma mansoni hypothetical protein 0.0181 0.1537 0.1655
Leishmania major DNA topoisomerase ii 0.0141 0.1168 0.1516
Loa Loa (eye worm) hypothetical protein 0.0024 0.0083 0.014
Leishmania major dihydrolipoamide dehydrogenase, putative 0.0843 0.7666 1
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0019 0.0035 0.0118
Entamoeba histolytica pyridine nucleotide-disulfide oxidoreductase family protein 0.0088 0.0675 0.2331
Wolbachia endosymbiont of Brugia malayi DNA gyrase, topoisomerase II, B subunit, GyrB 0.0087 0.0665 0.2146
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0313 0.2754 0.9369
Leishmania major NADH dehydrogenase, putative 0.0088 0.0675 0.0873
Mycobacterium leprae Probable DNA gyrase (subunit B) GyrB (DNA topoisomerase (ATP-hydrolysing)) (DNA topoisomerase II) (Type II DNA topoisomerase) 0.0039 0.0217 0.041
Trichomonas vaginalis conserved hypothetical protein 0.003 0.0131 0.0446
Trichomonas vaginalis xanthine dehydrogenase, putative 0.0185 0.1574 0.5357
Loa Loa (eye worm) TOPoisomerase family member 0.015 0.1242 0.2107
Mycobacterium tuberculosis Probable fructose-bisphosphate aldolase Fba 0.0153 0.1272 0.2218
Loa Loa (eye worm) hypothetical protein 0.0026 0.01 0.0169
Loa Loa (eye worm) hypothetical protein 0.0209 0.1793 0.304
Loa Loa (eye worm) hypothetical protein 0.0101 0.0795 0.1347
Onchocerca volvulus Transient receptor potential cation channel trpm homolog 0.0038 0.0205 0.0675
Echinococcus granulosus sodium and chloride dependent glycine 0.0044 0.0264 0.0258
Echinococcus multilocularis tyrosine protein kinase Src42A 0.0041 0.0239 0.0232
Echinococcus multilocularis transient receptor potential cation channel 0.0038 0.0208 0.0201
Echinococcus multilocularis g-protein coupled receptor 0.0209 0.1793 0.1787
Trypanosoma cruzi DNA topoisomerase II, putative 0.0141 0.1168 0.1516
Leishmania major isocitrate dehydrogenase [NADP], mitochondrial precursor, putative 0.0017 0.0014 0.0009
Loa Loa (eye worm) SRC-1 0.0041 0.0239 0.0404
Schistosoma mansoni norepinephrine/norepinephrine transporter 0.0044 0.0264 0.0278
Loa Loa (eye worm) voltage-gated potassium channel 0.0038 0.0205 0.0347
Loa Loa (eye worm) hypothetical protein 0.0024 0.0083 0.014
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0022 0.0057 0.009
Brugia malayi hypothetical protein 0.0038 0.0205 0.0322
Echinococcus multilocularis transcription factor Dp 1 0.0041 0.0236 0.0229
Echinococcus multilocularis potassium voltage gated channel subfamily D 0.0038 0.0205 0.0199
Mycobacterium leprae DIHYDROLIPOAMIDE DEHYDROGENASE LPD (LIPOAMIDE REDUCTASE (NADH)) (LIPOYL DEHYDROGENASE) (DIHYDROLIPOYL DEHYDROGENASE) (DIAPHORASE 0.0444 0.3965 1
Trypanosoma cruzi mitogen-activated protein kinase 11, putative 0.0055 0.0362 0.0464
Mycobacterium ulcerans glutamine-binding lipoprotein GlnH 0.004 0.0232 0.065
Mycobacterium ulcerans monoxygenase 0.0088 0.0675 0.2181
Brugia malayi Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain containing protein 0.0244 0.2121 0.3339
Onchocerca volvulus Alhambra homolog 0.0031 0.0146 0.0406
Echinococcus multilocularis cyclic nucleotide gated cation channel alpha 3 0.0043 0.0253 0.0247
Echinococcus multilocularis calmodulin 0.0026 0.01 0.0093
Schistosoma mansoni glutamate receptor kainate 0.0173 0.1462 0.1574
Brugia malayi hypothetical protein 0.0209 0.1793 0.2822
Plasmodium falciparum holo-[acyl-carrier-protein] synthase, putative 0.0025 0.0089 0.0132
Trichomonas vaginalis glucosylceramidase, putative 0.0181 0.1537 0.5228
Trypanosoma brucei trypanothione reductase 0.063 0.5689 0.7419
Schistosoma mansoni ataxia telangiectasia mutated (atm)-related 0.0048 0.0302 0.032
Schistosoma mansoni voltage-gated potassium channel 0.0038 0.0205 0.0215
Echinococcus multilocularis neuropeptides capa receptor 0.0209 0.1793 0.1787
Echinococcus multilocularis metabotropic glutamate receptor 2 0.0024 0.0083 0.0077
Schistosoma mansoni tyrosyl-DNA phosphodiesterase 0.0071 0.0511 0.0546
Echinococcus granulosus potassium voltage gated channel protein 0.0038 0.0205 0.0199
Trichomonas vaginalis PIKK family atypical protein kinase 0.0036 0.0188 0.0641
Echinococcus multilocularis tyrosine protein kinase HCK 0.0033 0.0165 0.0159
Trypanosoma cruzi DNA topoisomerase II, putative 0.0141 0.1168 0.1516
Echinococcus granulosus calmodulin 0.0026 0.01 0.0093
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0656 0.593 0.7734
Leishmania major cytochrome p450-like protein 0.0021 0.0049 0.0056
Echinococcus multilocularis voltage dependent calcium channel type d subunit 0.0138 0.1133 0.1128
Trypanosoma cruzi Present in the outer mitochondrial membrane proteome 4 0.0037 0.0197 0.0249
Plasmodium falciparum NAD(P)H-dependent glutamate synthase, putative 0.0088 0.0675 0.1166
Chlamydia trachomatis DNA gyrase subunit A 0.0032 0.0155 0.0232
Toxoplasma gondii histone lysine methyltransferase SET/SUV39 0.0033 0.0159 0.0256
Mycobacterium tuberculosis Putative ferredoxin reductase 0.0199 0.1701 0.2973
Schistosoma mansoni sodium/chloride dependent neurotransmitter transporter 0.0044 0.0264 0.0278
Schistosoma mansoni 60S ribosomal protein L21 0.0041 0.0239 0.0251
Schistosoma mansoni hypothetical protein 0.0038 0.0205 0.0215
Loa Loa (eye worm) hypothetical protein 0.0021 0.0047 0.008
Echinococcus multilocularis two pore calcium channel protein 1 0.0038 0.0205 0.0199
Mycobacterium tuberculosis Probable NADH-dependent glutamate synthase (small subunit) GltD (L-glutamate synthase) (L-glutamate synthetase) (NADH-glutamate 0.0088 0.0675 0.1166
Echinococcus granulosus G protein coupled 5 hydroxytryptamine receptor 0.0209 0.1793 0.1787
Loa Loa (eye worm) hypothetical protein 0.0209 0.1793 0.304
Toxoplasma gondii Sodium:neurotransmitter symporter family protein 0.0044 0.0264 0.0441
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0656 0.593 0.7734
Loa Loa (eye worm) glutamate receptor 0.0024 0.0083 0.014
Toxoplasma gondii non-proton pumping type-II NADH dehydrogenase I 0.0088 0.0675 0.1166
Schistosoma mansoni neuropeptide receptor 0.0209 0.1793 0.1932
Brugia malayi Transient-receptor-potential like protein 0.0038 0.0205 0.0322
Leishmania major 2-oxoglutarate dehydrogenase, e3 component, lipoamidedehydrogenase-like protein 0.0731 0.6626 0.8642
Echinococcus multilocularis metabotropic glutamate receptor 5 0.0024 0.0083 0.0077
Echinococcus multilocularis tyrosine protein kinase Fyn 0.0041 0.0239 0.0232
Schistosoma mansoni thyrotropin-releasing hormone receptor 0.0209 0.1793 0.1932
Plasmodium falciparum glutathione reductase 0.063 0.5689 1
Echinococcus multilocularis potassium voltage gated channel subfamily H 0.0074 0.0547 0.054
Loa Loa (eye worm) hypothetical protein 0.0022 0.0057 0.0097
Loa Loa (eye worm) CMGC/MAPK/ERK1 protein kinase 0.0055 0.0362 0.0614
Echinococcus granulosus lipoxygenase domain containing protein 0.0042 0.0248 0.0242
Echinococcus multilocularis glutamate synthase 0.0088 0.0675 0.0669
Brugia malayi Tyrosyl-DNA phosphodiesterase family protein 0.0071 0.0511 0.0805
Toxoplasma gondii NADPH-glutathione reductase 0.0333 0.2939 0.5155
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0209 0.1793 0.1932
Brugia malayi Serotonin receptor 0.0701 0.6352 1
Leishmania major phosphopantetheinyl transferase-like protein 0.0025 0.0089 0.0108
Trichomonas vaginalis conserved hypothetical protein 0.003 0.0131 0.0446
Brugia malayi Dopamine receptor 0.0209 0.1793 0.2822
Echinococcus granulosus FKBP12 rapamycin complex associated protein 0.0048 0.0302 0.0296
Plasmodium falciparum dihydrolipoyl dehydrogenase, mitochondrial 0.0333 0.2939 0.5155
Echinococcus granulosus cadherin EGF LAG seven pass G type receptor 0.0017 0.0013 0.0007
Trichomonas vaginalis glucosylceramidase, putative 0.0191 0.1627 0.5535
Loa Loa (eye worm) hypothetical protein 0.0201 0.1722 0.2921
Onchocerca volvulus 0.0209 0.1793 0.7902
Echinococcus multilocularis neuropeptide Y receptor 0.0209 0.1793 0.1787
Echinococcus multilocularis Nuclear hormone receptor family member nhr 41 0.0022 0.0057 0.0051
Echinococcus multilocularis hyperpolarization activated cyclic 0.0043 0.0253 0.0247
Loa Loa (eye worm) latrophilin receptor protein 2 0.0017 0.0013 0.0022
Echinococcus granulosus short transient receptor potential channel 6 0.0038 0.0208 0.0201
Echinococcus granulosus cyclic nucleotide gated cation channel 0.0043 0.0253 0.0247
Schistosoma mansoni glutamate receptor AMPA 0.0173 0.1462 0.1574
Brugia malayi Iron-sulfur cluster assembly accessory protein 0.0052 0.0335 0.0527
Plasmodium vivax thioredoxin reductase, putative 0.063 0.5689 1
Trichomonas vaginalis PIKK family atypical protein kinase 0.0016 0.0006 0.0022
Giardia lamblia Kinase, CMGC MAPK 0.0055 0.0362 0.11
Loa Loa (eye worm) hypothetical protein 0.0209 0.1793 0.304
Leishmania major calmodulin, putative 0.0026 0.01 0.0122
Echinococcus granulosus potassium voltage gated channel subfamily A 0.0038 0.0205 0.0199
Brugia malayi protein-tyrosine kinase 0.0037 0.0202 0.0318
Mycobacterium ulcerans epimerase 0.0022 0.0057 0.0046
Giardia lamblia DNA topoisomerase II 0.0142 0.117 0.3891
Echinococcus multilocularis FKBP12 rapamycin complex associated protein 0.0048 0.0302 0.0296
Echinococcus granulosus tyrosine kinase|tyrosine protein kinase Fyn 0.0037 0.0202 0.0196
Echinococcus granulosus tyrosine kinase 0.0037 0.0202 0.0196
Loa Loa (eye worm) G-protein-linked acetylcholine receptor protein 2 0.0209 0.1793 0.304
Onchocerca volvulus 0.0209 0.1793 0.7902
Brugia malayi calcium-independent alpha-latrotoxin receptor 2, putative 0.0017 0.0013 0.0021
Loa Loa (eye worm) G-protein coupled receptor 0.0209 0.1793 0.304
Trypanosoma cruzi Voltage-dependent calcium channel subunit, putative 0.0098 0.076 0.0984
Schistosoma mansoni voltage-gated potassium channel 0.0038 0.0205 0.0215
Schistosoma mansoni metabotropic glutamate receptor 0.0024 0.0083 0.0083
Leishmania major extracellular receptor, putative 0.0024 0.0083 0.01
Brugia malayi Pre-SET motif family protein 0.0223 0.1926 0.3032
Trypanosoma brucei inositol-1(or 4)-monophosphatase 1, putative 0.004 0.0223 0.0283
Trypanosoma cruzi tyrosyl-DNA Phosphodiesterase (Tdp1), putative 0.0071 0.0511 0.0659
Echinococcus multilocularis hepatocyte nuclear factor 4 alpha 0.0022 0.0057 0.0051
Brugia malayi Isocitrate dehydrogenase 0.0017 0.0014 0.0021
Trichomonas vaginalis PIKK family atypical protein kinase 0.0036 0.0188 0.0641
Brugia malayi F/Y-rich N-terminus family protein 0.0021 0.0049 0.0077
Loa Loa (eye worm) hypothetical protein 0.0394 0.3507 0.5947
Trypanosoma brucei isocitrate dehydrogenase, putative 0.0017 0.0014 0.0009
Trichomonas vaginalis PIKK family atypical protein kinase 0.0029 0.0123 0.0419
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0019 0.0035 0.0118
Echinococcus granulosus calcium activated potassium channel 0.0038 0.021 0.0203
Trichomonas vaginalis glucosylceramidase, putative 0.0276 0.2417 0.8222
Schistosoma mansoni retinoic acid receptor RXR 0.0022 0.0057 0.0055
Mycobacterium tuberculosis Probable endonuclease IV End (endodeoxyribonuclease IV) (apurinase) 0.0082 0.0617 0.1063
Schistosoma mansoni rab6-interacting 0.0042 0.0248 0.0261
Echinococcus granulosus potassium voltage gated channel subfamily D 0.0038 0.0205 0.0199
Trichomonas vaginalis apoptosis inducing factor, putative 0.0088 0.0675 0.2297
Echinococcus multilocularis histone lysine N methyltransferase SETMAR 0.0033 0.0159 0.0153
Trypanosoma brucei NADH dehydrogenase 0.0088 0.0675 0.0873
Loa Loa (eye worm) TYRA-2 protein 0.0209 0.1793 0.304
Loa Loa (eye worm) follicle stimulating hormone receptor 0.0209 0.1793 0.304
Trypanosoma brucei mitogen activated protein kinase 4, putative 0.0055 0.0362 0.0464
Plasmodium falciparum dihydrolipoyl dehydrogenase, apicoplast 0.0333 0.2939 0.5155
Leishmania major hypothetical protein, conserved 0.0027 0.0107 0.0131
Loa Loa (eye worm) hypothetical protein 0.0019 0.0032 0.0055
Loa Loa (eye worm) transcription factor SMAD2 0.0128 0.104 0.1764
Treponema pallidum DNA gyrase, subunit A (gyrA) 0.0032 0.0155 0.0385
Loa Loa (eye worm) hypothetical protein 0.0038 0.0205 0.0347
Schistosoma mansoni survival motor neuron protein 0.0052 0.0335 0.0355
Echinococcus multilocularis glutamate receptor subunit protein glur 0.0074 0.0543 0.0537
Schistosoma mansoni retinoid-x-receptor (RXR) 0.0022 0.0057 0.0055
Trichomonas vaginalis PIKK family atypical protein kinase 0.0038 0.0211 0.0719
Echinococcus granulosus tyrosine protein kinase Src42A 0.0041 0.0239 0.0232
Schistosoma mansoni voltage-gated potassium channel 0.0046 0.0287 0.0303
Echinococcus multilocularis TRP (transient receptor potential) channel 0.0038 0.0205 0.0199
Loa Loa (eye worm) CXXC zinc finger family protein 0.0031 0.0142 0.024
Trichomonas vaginalis glucosylceramidase, putative 0.0181 0.1537 0.5228
Brugia malayi Nuclear hormone receptor-like 1 0.0022 0.0057 0.009
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0209 0.1793 0.1787
Toxoplasma gondii transporter, cation channel family protein 0.0038 0.0205 0.0337
Schistosoma mansoni hypothetical protein 0.0031 0.0146 0.0151
Schistosoma mansoni thyroid hormone receptor 0.0022 0.0057 0.0055
Echinococcus multilocularis microtubule associated protein 2 0.0738 0.6697 0.6694
Loa Loa (eye worm) phosphatidylinositol 3 0.0016 0.0006 0.001
Leishmania major ferric reductase, putative 0.0036 0.0195 0.0246
Echinococcus granulosus Basic leucine zipper bZIP transcription factor 0.009 0.0689 0.0683
Echinococcus multilocularis rhodopsin orphan GPCR 0.0209 0.1793 0.1787
Echinococcus multilocularis calmodulin 0.0026 0.01 0.0093
Plasmodium falciparum apurinic/apyrimidinic endonuclease Apn1, putative 0.0082 0.0617 0.1063
Echinococcus granulosus Polycystic kidney disease protein 0.0042 0.0248 0.0242
Echinococcus granulosus glutamate receptor NMDA 0.0084 0.0639 0.0633
Trypanosoma brucei C-8 sterol isomerase, putative 0.0394 0.3507 0.457
Echinococcus multilocularis 7TM GPCR, rhodopsin 0.0209 0.1793 0.1787
Treponema pallidum 4'-phosphopantetheinyl transferase 0.0025 0.0089 0.0157
Schistosoma mansoni voltage-gated potassium channel 0.0038 0.0205 0.0215
Onchocerca volvulus 0.0209 0.1793 0.7902
Trypanosoma cruzi mitogen activated protein kinase 2, putative 0.0055 0.0362 0.0464
Trypanosoma cruzi cytochrome P450, putative 0.0021 0.0049 0.0056
Echinococcus granulosus voltage gated potassium channel 0.0038 0.0205 0.0199
Loa Loa (eye worm) TK protein kinase 0.0037 0.0202 0.0343
Echinococcus granulosus potassium:sodium hyperpolarization activated 0.0043 0.0253 0.0247
Trichomonas vaginalis conserved hypothetical protein 0.0042 0.0244 0.0831
Trypanosoma cruzi apurinic/apyrimidinic endonuclease 0.002 0.0043 0.0048
Echinococcus multilocularis Glutamate receptor, ionotropic kainate 2 0.0198 0.1688 0.1682
Loa Loa (eye worm) hypothetical protein 0.0209 0.1793 0.304
Loa Loa (eye worm) CYP4Cod1 0.0021 0.0049 0.0083
Echinococcus multilocularis thioredoxin glutathione reductase 0.063 0.5689 0.5686
Trypanosoma cruzi mitochondrial DNA topoisomerase II, putative 0.0168 0.1412 0.1835
Loa Loa (eye worm) voltage and ligand gated potassium channel 0.0074 0.0547 0.0927
Mycobacterium tuberculosis Dihydrolipoamide dehydrogenase LpdC (lipoamide reductase (NADH)) (lipoyl dehydrogenase) (dihydrolipoyl dehydrogenase) (diaphoras 0.0444 0.3965 0.6963
Mycobacterium tuberculosis Inositol-1-monophosphatase SuhB 0.0035 0.0185 0.0302
Echinococcus multilocularis sodium dependent neurotransmitter transporter 0.0044 0.0264 0.0258
Entamoeba histolytica glutamate synthase beta subunit, putative 0.0088 0.0675 0.2331
Onchocerca volvulus 0.0209 0.1793 0.7902
Schistosoma mansoni calmodulin 0.0026 0.01 0.0101
Onchocerca volvulus 0.0042 0.0248 0.087
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0313 0.2754 0.9369
Schistosoma mansoni voltage-gated potassium channel 0.0038 0.0205 0.0215
Echinococcus granulosus g protein coupled receptor 0.0209 0.1793 0.1787
Echinococcus granulosus tyrosine protein kinase Src42A 0.0035 0.0183 0.0177
Schistosoma mansoni hypothetical protein 0.0438 0.3911 0.4222
Echinococcus multilocularis NADP dependent isocitrate dehydrogenase 0.0017 0.0014 0.0007
Echinococcus granulosus sex peptide receptor 0.0209 0.1793 0.1787
Toxoplasma gondii ATPase/histidine kinase/DNA gyrase B/HSP90 domain-containing protein 0.0087 0.0665 0.1148
Echinococcus multilocularis isocitrate dehydrogenase 0.0017 0.0014 0.0007
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0019 0.0035 0.0118
Trypanosoma brucei pyridine nucleotide-disulphide oxidoreductase, putative 0.0088 0.0675 0.0873
Giardia lamblia Glycerol-3-phosphate dehydrogenase 0.0088 0.0675 0.2181
Plasmodium vivax AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.002 0.0043 0.0053
Brugia malayi Steroid receptor seven-up type 2 0.0022 0.0057 0.009
Brugia malayi hypothetical protein 0.0024 0.0083 0.013
Brugia malayi chromobox protein homolog 3 0.0042 0.0244 0.0384
Brugia malayi Voltage-gated potassium channel, Shab-family (KCNB, Kv2-like) alpha-subunit. C. elegans exp-2 ortholog 0.0038 0.0205 0.0322
Echinococcus multilocularis lipoxygenase domain containing protein 0.0042 0.0248 0.0242
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0731 0.6626 0.8642
Mycobacterium ulcerans fructose-bisphosphate aldolase 0.0153 0.1272 0.4243
Echinococcus granulosus calmodulin 0.0026 0.01 0.0093
Echinococcus multilocularis Basic leucine zipper (bZIP) transcription factor 0.009 0.0689 0.0683
Plasmodium vivax holo-[acyl-carrier-protein] synthase, putative 0.0025 0.0089 0.0132
Treponema pallidum oxidoreductase 0.0088 0.0675 0.2181
Echinococcus multilocularis transient receptor potential cation channel 0.0038 0.0205 0.0199
Schistosoma mansoni polycystin 1-related 0.0042 0.0248 0.0261
Trypanosoma brucei NADPH:adrenodoxin oxidoreductase, mitochondrial, putative 0.0088 0.0675 0.0873
Mycobacterium ulcerans NADPH:adrenodoxin oxidoreductase FprA 0.0088 0.0675 0.2181
Echinococcus multilocularis voltage gated hydrogen channel 1 0.0038 0.0205 0.0199
Brugia malayi cation channel family protein 0.0038 0.0205 0.0322
Echinococcus granulosus potassium voltage gated channel protein 0.0038 0.0205 0.0199
Trypanosoma brucei Phosphatidylinositol 3-kinase tor1 0.0048 0.0302 0.0387
Wolbachia endosymbiont of Brugia malayi NADPH-dependent glutamate synthase beta chain 0.0088 0.0675 0.2181
Loa Loa (eye worm) hypothetical protein 0.0652 0.5896 1
Trichomonas vaginalis PIKK family atypical protein kinase 0.0036 0.0188 0.0641
Echinococcus granulosus DNA apurinic or apyrimidinic site lyase 0.002 0.0043 0.0037
Leishmania major hypothetical protein, conserved 0.0037 0.0197 0.0249
Onchocerca volvulus 0.008 0.0596 0.2457
Echinococcus granulosus dihydrolipoamide dehydrogenase 0.0333 0.2939 0.2935
Loa Loa (eye worm) heterochromatin protein 1 0.0075 0.0548 0.0928
Echinococcus multilocularis L aminoadipate semialdehyde 0.0089 0.0681 0.0675
Echinococcus multilocularis tyrosine protein kinase Src64B 0.0041 0.0239 0.0232
Echinococcus multilocularis tyrosine protein kinase Fyn 0.0041 0.0239 0.0232
Loa Loa (eye worm) calcium channel 0.0138 0.1133 0.1922
Schistosoma mansoni tyrosine kinase 0.0085 0.0643 0.0688
Echinococcus granulosus 7tm_1 domain containing protein 0.0209 0.1793 0.1787
Schistosoma mansoni peptide (FMRFamide/somatostatin)-like receptor 0.0209 0.1793 0.1932
Toxoplasma gondii thioredoxin reductase 0.063 0.5689 1
Leishmania major hypothetical protein, conserved 0.0088 0.0675 0.0873
Trichomonas vaginalis PIKK family atypical protein kinase 0.0016 0.0006 0.0022
Echinococcus multilocularis thyrotropin releasing hormone receptor 0.0209 0.1793 0.1787
Trypanosoma cruzi isocitrate dehydrogenase [NADP], mitochondrial precursor, putative 0.0017 0.0014 0.0009
Trypanosoma brucei calmodulin 0.0026 0.01 0.0122
Loa Loa (eye worm) unidentified vitellogenin-linked transcript protein 6 0.0209 0.1793 0.304
Loa Loa (eye worm) hypothetical protein 0.047 0.4207 0.7134
Loa Loa (eye worm) nuclear hormone receptor family member nhr-1 0.0022 0.0057 0.0097
Trichomonas vaginalis PIKK family atypical protein kinase 0.0028 0.0121 0.041
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0313 0.2754 0.9369
Trypanosoma brucei dihydrolipoamide dehydrogenase, point mutation 0.0656 0.593 0.7734
Echinococcus multilocularis sodium and chloride dependent glycine 0.0044 0.0264 0.0258
Echinococcus multilocularis Glutamate receptor, ionotropic kainate 3 0.0115 0.0918 0.0912
Brugia malayi cation channel family protein 0.0038 0.0205 0.0322
Echinococcus multilocularis insulin receptor 0.0052 0.034 0.0334
Echinococcus multilocularis ecdysone induced protein 78C 0.0022 0.0057 0.0051
Schistosoma mansoni tyrosine kinase 0.0041 0.0239 0.0251
Schistosoma mansoni steroid hormone receptor ad4bp 0.0022 0.0057 0.0055
Echinococcus multilocularis short transient receptor potential channel 6 0.0038 0.0208 0.0201
Trichomonas vaginalis disulfide oxidoreductase, putative 0.0088 0.0675 0.2297
Loa Loa (eye worm) inositol-1 0.004 0.0223 0.0378
Echinococcus multilocularis survival motor neuron protein 1 0.0253 0.2201 0.2196
Brugia malayi glutathione reductase 0.063 0.5689 0.8955
Brugia malayi hypothetical protein 0.0253 0.2201 0.3464
Schistosoma mansoni hypothetical protein 0.0017 0.0013 0.0008
Schistosoma mansoni neuropeptide receptor 0.0209 0.1793 0.1932
Loa Loa (eye worm) hypothetical protein 0.0061 0.0421 0.0713
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0209 0.1793 0.1932
Echinococcus granulosus neuropeptide Y receptor 0.0209 0.1793 0.1787
Leishmania major trypanothione reductase 0.063 0.5689 0.7419
Brugia malayi G-protein coupled receptor 0.0209 0.1793 0.2822
Trypanosoma cruzi Phosphatidylinositol 3-kinase tor2 0.0048 0.0302 0.0387
Entamoeba histolytica hypothetical protein 0.0025 0.0089 0.0167
Mycobacterium leprae PROBABLE NADPH:ADRENODOXIN OXIDOREDUCTASE FPRB (ADRENODOXIN REDUCTASE) (AR) (FERREDOXIN-NADP(+) REDUCTASE) 0.0088 0.0675 0.1582
Echinococcus granulosus 7TM GPCR rhodopsin 0.0209 0.1793 0.1787
Leishmania major tyrosyl-DNA phosphodiesterase 1 0.0071 0.0511 0.0659
Loa Loa (eye worm) hypothetical protein 0.0228 0.1964 0.3331
Echinococcus multilocularis voltage dependent calcium channel 0.0138 0.1133 0.1128
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0843 0.7666 1
Trypanosoma cruzi NADPH:adrenodoxin oxidoreductase, mitochondrial, putative 0.0088 0.0675 0.0873
Echinococcus granulosus insulin growth factor 1 receptor beta 0.0052 0.034 0.0334
Trichomonas vaginalis glutathione reductase, putative 0.0333 0.2939 1
Brugia malayi Nuclear hormone receptor family member nhr-40 0.0022 0.0057 0.009
Echinococcus multilocularis rhodopsin orphan GPCR 0.0209 0.1793 0.1787
Echinococcus granulosus Ribosomal protein S1 RNA binding domain 0.0074 0.0543 0.0537
Trichomonas vaginalis calmodulin, putative 0.0026 0.01 0.034
Echinococcus multilocularis alpha 1A adrenergic receptor 0.0209 0.1793 0.1787
Mycobacterium tuberculosis NADPH-dependent mycothiol reductase Mtr 0.063 0.5689 1
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.0038 0.0205 0.0337
Trichomonas vaginalis glucosylceramidase, putative 0.0181 0.1537 0.5228
Brugia malayi Serotonin/octopamine receptor family protein 7 0.0525 0.4724 0.7436
Brugia malayi photoreceptor-specific nuclear receptor 0.0022 0.0057 0.009
Toxoplasma gondii pyruvate dehydrogenase complex subunit PDH-E3II 0.0333 0.2939 0.5155
Onchocerca volvulus Dual oxidase homolog 0.0078 0.0577 0.2369
Onchocerca volvulus 0.0254 0.2213 0.9817
Onchocerca volvulus Adenylate cyclase type 3 homolog 0.0231 0.1997 0.8833
Echinococcus multilocularis calmodulin 0.0026 0.01 0.0093
Plasmodium vivax NAD(P)H-dependent glutamate synthase, putative 0.0088 0.0675 0.1166
Loa Loa (eye worm) ryanodine receptor 0.0038 0.0205 0.0347
Brugia malayi Thioredoxin reductase 0.063 0.5689 0.8955
Schistosoma mansoni cpg binding protein 0.0032 0.0158 0.0164
Brugia malayi Voltage-gated potassium channel, EAG (KCNH1)-related. C. elegans egl-2 ortholog 0.0046 0.0287 0.0451
Loa Loa (eye worm) hypothetical protein 0.0082 0.0617 0.1046
Schistosoma mansoni inositol monophosphatase 0.004 0.0223 0.0234
Loa Loa (eye worm) hypothetical protein 0.0038 0.0205 0.0347
Schistosoma mansoni cyclic-nucleotide-gated cation channel 0.0043 0.0253 0.0267
Loa Loa (eye worm) RGC/RGC protein kinase 0.003 0.0135 0.0228
Echinococcus multilocularis glutamate receptor, ionotrophic, AMPA 3 0.0198 0.1688 0.1682
Chlamydia trachomatis DNA gyrase subunit A 0.0032 0.0155 0.0232
Schistosoma mansoni cyclic-nucleotide-gated cation channel 0.0043 0.0253 0.0267
Echinococcus multilocularis glutamate receptor 2 0.0198 0.1688 0.1682
Schistosoma mansoni glutamate receptor AMPA 0.0173 0.1462 0.1574
Brugia malayi Nuclear hormone receptor family member nhr-1 0.0022 0.0057 0.009
Echinococcus granulosus glutamate receptor 2 0.0198 0.1688 0.1682
Echinococcus granulosus glutamate NMDA receptor subunit 0.035 0.3103 0.3099
Echinococcus granulosus dihydropyrimidine dehydrogenase NADP 0.0088 0.0675 0.0669
Schistosoma mansoni sodium-dependent amino acid transporter 0.0044 0.0264 0.0278
Wolbachia endosymbiont of Brugia malayi thioredoxin reductase 0.0088 0.0675 0.2181
Trichomonas vaginalis voltage and ligand gated potassium channel, putative 0.0043 0.0253 0.0862
Trichomonas vaginalis PIKK family atypical protein kinase 0.0038 0.0211 0.0719
Brugia malayi alpha keto acid dehydrogenase complex, E3 component, lipoamide dehydrogenase 0.0244 0.2121 0.3339
Plasmodium vivax glutathione reductase, putative 0.063 0.5689 1
Trypanosoma brucei hypothetical protein, conserved 0.0025 0.0089 0.0108
Echinococcus multilocularis G protein coupled 5 hydroxytryptamine receptor 0.0209 0.1793 0.1787
Schistosoma mansoni chromobox protein 0.0075 0.0548 0.0585
Toxoplasma gondii hypothetical protein 0.0044 0.0264 0.0441
Brugia malayi NADPH:adrenodoxin oxidoreductase, mitochondrial precursor 0.0088 0.0675 0.1063
Giardia lamblia Fructose-bisphosphate aldolase 0.0313 0.2754 0.936
Plasmodium falciparum LCCL domain-containing protein 0.0042 0.0248 0.0413
Onchocerca volvulus 0.0209 0.1793 0.7902
Echinococcus granulosus neuropeptides capa receptor 0.0209 0.1793 0.1787
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0022 0.0057 0.0051
Echinococcus granulosus potassium voltage gated channel subfamily D 0.0038 0.0205 0.0199
Schistosoma mansoni transient receptor potential channel 0.0038 0.0205 0.0215
Trypanosoma cruzi extracellular receptor, putative 0.0024 0.0083 0.01
Loa Loa (eye worm) hypothetical protein 0.0209 0.1793 0.304
Echinococcus multilocularis shaker cognate 0.0038 0.0205 0.0199
Brugia malayi hypothetical protein 0.0042 0.0248 0.039
Giardia lamblia PHD finger protein 15 0.0031 0.0146 0.0354
Schistosoma mansoni nuclear hormone receptor 0.0022 0.0057 0.0055
Treponema pallidum sodium- and chloride- dependent transporter 0.0259 0.2254 0.7632
Brugia malayi Voltage-gated calcium channel, T-type, alpha subunit. C. elegans cca-1 ortholog 0.0038 0.0205 0.0322
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0033 0.0159 0.0165
Echinococcus multilocularis dihydrolipoamide dehydrogenase 0.0333 0.2939 0.2935
Mycobacterium ulcerans carbon monoxyde dehydrogenase large chain CoxL 0.0055 0.0366 0.1114
Echinococcus multilocularis tyrosine protein kinase Blk 0.0037 0.0202 0.0196
Entamoeba histolytica phosphatidylinositol3-kinaseTor2, putative 0.0048 0.0302 0.0956
Echinococcus multilocularis receptor type guanylyl cyclase 0.003 0.0135 0.0128
Echinococcus granulosus inositol monophosphatase 1 0.004 0.0223 0.0217
Loa Loa (eye worm) hypothetical protein 0.0209 0.1793 0.304
Leishmania major calmodulin, putative 0.0026 0.01 0.0122
Onchocerca volvulus DNA topoisomerase 2 homolog 0.0101 0.0793 0.3352
Brugia malayi hypothetical protein 0.0042 0.0248 0.039
Mycobacterium leprae possible inositol monophosphatase SubH (IMPase) (inositol-1-phosphatase) (I-1-Pase ). 0.0035 0.0185 0.0327
Schistosoma mansoni RAR-like nuclear receptor 0.0022 0.0057 0.0055
Schistosoma mansoni chromobox protein 0.0075 0.0548 0.0585
Echinococcus multilocularis potassium voltage gated channel subfamily A 0.0038 0.0205 0.0199
Loa Loa (eye worm) hypothetical protein 0.0038 0.0205 0.0347
Trypanosoma brucei protein kinase, putative 0.0055 0.0362 0.0464
Echinococcus granulosus DNA topoisomerase 2 alpha 0.015 0.1242 0.1237
Chlamydia trachomatis thioredoxin reductase 0.0088 0.0675 0.2057
Trichomonas vaginalis myo inositol monophosphatase, putative 0.004 0.0223 0.0759
Echinococcus multilocularis serotonin receptor 0.047 0.4207 0.4203
Entamoeba histolytica FKBP-rapamycin associated protein (FRAP), putative 0.0048 0.0302 0.0956
Schistosoma mansoni ATP-binding cassette transporter 0.0174 0.1464 0.1577
Echinococcus granulosus tyrosine protein kinase Fyn 0.0041 0.0239 0.0232
Echinococcus multilocularis glutamate receptor 2 0.0173 0.1462 0.1456
Echinococcus multilocularis NADP dependent isocitrate dehydrogenase 0.0017 0.0014 0.0007
Echinococcus granulosus receptor type guanylyl cyclase 0.003 0.0135 0.0128
Trichomonas vaginalis disulfide oxidoreductase, putative 0.0088 0.0675 0.2297
Echinococcus multilocularis g protein coupled receptor 0.0209 0.1793 0.1787
Schistosoma mansoni voltage-gated potassium channel 0.0038 0.0205 0.0215
Schistosoma mansoni high voltage-activated calcium channel Cav2A 0.0138 0.1133 0.1219
Loa Loa (eye worm) glutathione reductase 0.063 0.5689 0.9648
Treponema pallidum DNA gyrase, subunit B (gyrB) 0.0087 0.0665 0.2146
Trichomonas vaginalis chromobox protein, putative 0.0075 0.0548 0.1863
Echinococcus multilocularis tyrosine protein kinase Src42A 0.0035 0.0183 0.0177
Loa Loa (eye worm) nuclear hormone receptor family member nhr-31 0.0022 0.0057 0.0097
Echinococcus granulosus neuropeptide receptor 0.0209 0.1793 0.1787
Trypanosoma cruzi pyridine nucleotide-disulphide oxidoreductase, putative 0.0088 0.0675 0.0873
Chlamydia trachomatis dihydrolipoyl dehydrogenase 0.0333 0.2939 1
Trypanosoma brucei DNA topoisomerase ii 0.0168 0.1412 0.1835
Plasmodium falciparum ferrodoxin reductase-like protein 0.0088 0.0675 0.1166
Treponema pallidum amino acid ABC transporter, periplasmic binding protein (hisJ) 0.004 0.0232 0.065
Schistosoma mansoni sodium/chloride dependent neurotransmitter transporter 0.0044 0.0264 0.0278
Onchocerca volvulus 0.0259 0.2254 1
Giardia lamblia Calmodulin 0.0026 0.01 0.0194
Loa Loa (eye worm) steroid hormone receptor 0.0022 0.0057 0.0097
Echinococcus multilocularis glutamate receptor NMDA 0.0084 0.0639 0.0633
Brugia malayi Doublecortin family protein 0.0042 0.0248 0.039
Echinococcus granulosus G protein coupled receptor 139 0.0209 0.1793 0.1787
Echinococcus granulosus cyclic nucleotide gated cation channel 0.0043 0.0253 0.0247
Plasmodium vivax dihydrolipoyl dehydrogenase, mitochondrial, putative 0.0333 0.2939 0.5155
Leishmania major mitogen activated protein kinase, putative,map kinase, putative 0.0055 0.0362 0.0464
Wolbachia endosymbiont of Brugia malayi thioredoxin reductase 0.0088 0.0675 0.2181
Loa Loa (eye worm) hypothetical protein 0.0024 0.0083 0.014
Schistosoma mansoni transient receptor potential cation channel subfamily m member 0.0038 0.0205 0.0215
Toxoplasma gondii Sodium:neurotransmitter symporter family protein 0.0044 0.0264 0.0441
Echinococcus granulosus tyrosyl DNA phosphodiesterase 1 0.0071 0.0511 0.0505
Loa Loa (eye worm) hypothetical protein 0.0044 0.0264 0.0447
Echinococcus multilocularis insulin growth factor 1 receptor beta 0.0052 0.034 0.0334
Echinococcus granulosus tyrosine protein kinase Lyn 0.0042 0.0243 0.0237
Toxoplasma gondii selenide, water dikinase 0.0088 0.0675 0.1166
Echinococcus granulosus histone lysine methyltransferase setb 0.0033 0.0159 0.0153
Trypanosoma cruzi calmodulin, putative 0.0026 0.01 0.0122
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0022 0.0057 0.009
Loa Loa (eye worm) hypothetical protein 0.0017 0.0013 0.0022
Echinococcus granulosus voltage gated sodium channel Nav1 alpha subunit 0.0497 0.4457 0.4453
Schistosoma mansoni transient receptor potential channel 0.0038 0.0208 0.0217
Echinococcus granulosus sulfide:quinone oxidoreductase 0.0088 0.0675 0.0669
Chlamydia trachomatis DNA gyrase subunit B 0.0087 0.0665 0.2021
Mycobacterium ulcerans hypothetical protein 0.003 0.0136 0.032
Echinococcus granulosus peptide allatostatin:somatostatin 0.0209 0.1793 0.1787
Loa Loa (eye worm) exodeoxyribonuclease III family protein 0.002 0.0043 0.0073
Loa Loa (eye worm) hypothetical protein 0.0022 0.0057 0.0097
Echinococcus granulosus glutamate receptor ionotropic kainate 3 0.0074 0.0543 0.0537
Echinococcus granulosus epidermal growth factor receptor 0.0087 0.0662 0.0656
Plasmodium falciparum FAD-linked sulfhydryl oxidase ERV1, putative 0.0037 0.0197 0.0323
Echinococcus granulosus epidermal growth factor receptor 0.0161 0.1346 0.134
Schistosoma mansoni peptide (allatostatin)-like receptor 0.0209 0.1793 0.1932
Echinococcus granulosus two pore calcium channel protein 2 0.0038 0.0205 0.0199
Mycobacterium ulcerans aerobic-type carbon monoxide dehydrogenase subunit CoxL_2 0.0087 0.0667 0.2152
Loa Loa (eye worm) hypothetical protein 0.0053 0.0352 0.0597
Onchocerca volvulus 0.0026 0.01 0.0194
Schistosoma mansoni biogenic amine (octopamine/dopamine) receptor 0.0525 0.4724 0.5101
Onchocerca volvulus 0.003 0.0135 0.0354
Schistosoma mansoni serine/threonine protein kinase 0.0055 0.0362 0.0385
Echinococcus multilocularis epidermal growth factor receptor 0.0087 0.0662 0.0656
Echinococcus granulosus serotonin transporter 0.0259 0.2254 0.2249
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0022 0.0057 0.0051
Schistosoma mansoni ap endonuclease 0.002 0.0043 0.004
Trypanosoma cruzi trypanothione reductase, putative 0.0333 0.2939 0.3829
Loa Loa (eye worm) hypothetical protein 0.0069 0.0498 0.0845
Trypanosoma brucei calmodulin 0.0026 0.01 0.0122
Mycobacterium ulcerans hypothetical protein 0.0088 0.0675 0.2181
Echinococcus multilocularis tyrosine protein kinase lyn tyrosine protein kinase blk 0.0041 0.0239 0.0232
Mycobacterium ulcerans NADH dehydrogenase 0.0088 0.0675 0.2181
Loa Loa (eye worm) hypothetical protein 0.0209 0.1793 0.304
Leishmania major hypothetical protein, conserved 0.0088 0.0675 0.0873
Trypanosoma brucei DNA topoisomerase II alpha, putative 0.0141 0.1168 0.1516
Brugia malayi G-protein-linked acetylcholine receptor protein 2, putative 0.0209 0.1793 0.2822
Toxoplasma gondii pyridine nucleotide-disulfide oxidoreductase domain-containing protein 0.0088 0.0675 0.1166
Trichomonas vaginalis PIKK family atypical protein kinase 0.0026 0.0097 0.0331
Loa Loa (eye worm) hypothetical protein 0.0209 0.1793 0.304
Mycobacterium leprae conserved hypothetical protein 0.0025 0.0089 0.0082
Loa Loa (eye worm) hypothetical protein 0.0044 0.0264 0.0447
Brugia malayi Furin-like cysteine rich region family protein 0.0161 0.1346 0.2118
Plasmodium vivax hypothetical protein, conserved 0.0031 0.0146 0.0233
Echinococcus granulosus potassium voltage gated channel subfamily C 0.0038 0.0205 0.0199
Echinococcus granulosus nmda type glutamate receptor 0.0199 0.1699 0.1694
Chlamydia trachomatis endonuclease IV 0.0082 0.0617 0.1852
Brugia malayi gonadotropin-releasing hormone receptor 2 0.0209 0.1793 0.2822
Schistosoma mansoni calcium channel voltage-dependent p/q type alpha 1a-related 0.0038 0.0205 0.0215
Loa Loa (eye worm) hypothetical protein 0.0209 0.1793 0.304
Brugia malayi Voltage-gated potassium channel, HERG (KCNH2)-related. C. elegans unc-103 ortholog 0.0074 0.0547 0.086
Wolbachia endosymbiont of Brugia malayi DNA gyrase subunit A 0.0032 0.0155 0.0385
Schistosoma mansoni tyrosine kinase 0.0052 0.034 0.0361
Brugia malayi nuclear receptor NHR-88 0.0022 0.0057 0.009
Loa Loa (eye worm) MH2 domain-containing protein 0.0128 0.104 0.1764
Mycobacterium tuberculosis Probable thioredoxin reductase TrxB2 (TRXR) (TR) 0.0088 0.0675 0.1166
Echinococcus granulosus neuropeptides capa receptor 0.0209 0.1793 0.1787
Echinococcus multilocularis histone lysine methyltransferase setb histone lysine methyltransferase eggless 0.0033 0.0159 0.0153
Brugia malayi Tachykinin-like peptides receptor 99D 0.0209 0.1793 0.2822
Echinococcus granulosus thioredoxin glutathione reductase 0.063 0.5689 0.5686
Echinococcus granulosus melanoma receptor tyrosine protein kinase 0.0087 0.0662 0.0656
Trypanosoma brucei dihydrolipoamide dehydrogenase 0.0731 0.6626 0.8642
Schistosoma mansoni biogenic amine (5HT) receptor 0.047 0.4207 0.4542
Mycobacterium ulcerans phosphopantetheinyl transferase, PptII 0.0025 0.0089 0.0157
Echinococcus multilocularis calmodulin 0.0026 0.01 0.0093
Echinococcus granulosus NADPH:adrenodoxin oxidoreductase 0.0088 0.0675 0.0669
Mycobacterium ulcerans carbon monoxyde dehydrogenase medium chain CoxM 0.0063 0.0437 0.1359
Brugia malayi Ryanodine Receptor TM 4-6 family protein 0.0038 0.0205 0.0323
Entamoeba histolytica calmodulin, putative 0.0026 0.01 0.0208
Loa Loa (eye worm) hypothetical protein 0.0021 0.0047 0.008
Mycobacterium tuberculosis Conserved hypothetical protein 0.0022 0.0057 0.0076
Trichomonas vaginalis PIKK family atypical protein kinase 0.0048 0.0302 0.1029
Mycobacterium tuberculosis NAD(P)H quinone reductase LpdA 0.0444 0.3965 0.6963
Echinococcus granulosus neuropeptide FF receptor 2 0.0209 0.1793 0.1787
Brugia malayi hypothetical protein 0.0209 0.1793 0.2822
Schistosoma mansoni voltage-gated potassium channel 0.0038 0.0205 0.0215
Schistosoma mansoni ap endonuclease 0.002 0.0043 0.004
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0066 0.0472 0.0503
Echinococcus granulosus tyrosine protein kinase Fyn 0.0041 0.0239 0.0232
Loa Loa (eye worm) hypothetical protein 0.0057 0.038 0.0645
Trichomonas vaginalis voltage and ligand gated potassium channel, putative 0.0049 0.0313 0.1064
Echinococcus granulosus somatostatin receptor 0.0209 0.1793 0.1787
Schistosoma mansoni hypothetical protein 0.0074 0.0543 0.058
Schistosoma mansoni tyrosine kinase 0.0087 0.0662 0.0709
Plasmodium vivax ferrodoxin reductase, putative 0.0088 0.0675 0.1166
Echinococcus granulosus g protein coupled receptor 0.0209 0.1793 0.1787
Echinococcus granulosus potassium voltage gated channel protein 0.0038 0.0205 0.0199
Onchocerca volvulus 0.0209 0.1793 0.7902
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0022 0.0057 0.009
Echinococcus multilocularis DNA topoisomerase 2 alpha 0.015 0.1242 0.1237
Echinococcus granulosus transient receptor potential cation channel 0.0038 0.0205 0.0199
Schistosoma mansoni cyclic-nucleotide-gated cation channel 0.0043 0.0253 0.0267
Mycobacterium ulcerans cytochrome P450 185A4 Cyp185A4 0.0021 0.0049 0.002
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0019 0.0035 0.0118
Mycobacterium tuberculosis Probable NADPH dependent 2,4-dienoyl-CoA reductase FadH (2,4-dienoyl coenzyme A reductase) (4-enoyl-CoA reductase) 0.0088 0.0675 0.1166
Echinococcus granulosus glutamate receptor ionotrophic AMPA 3 0.0198 0.1688 0.1682
Onchocerca volvulus 0.0209 0.1793 0.7902
Mycobacterium ulcerans glutamate synthase subunit beta 0.0088 0.0675 0.2181
Entamoeba histolytica myo-inositol monophosphatase, putative 0.004 0.0223 0.0663
Schistosoma mansoni voltage-gated potassium channel 0.0043 0.0253 0.0267
Plasmodium vivax FAD-linked sulfhydryl oxidase ERV1, putative 0.0037 0.0197 0.0323
Brugia malayi jmjC domain containing protein 0.0102 0.0803 0.1264
Mycobacterium ulcerans carbon monoxyde dehydrogenase small chain CoxS 0.0035 0.0185 0.0489
Echinococcus multilocularis cyclic nucleotide gated cation channel 0.0043 0.0253 0.0247
Trichomonas vaginalis glutamate synthase, putative 0.0088 0.0675 0.2297
Echinococcus multilocularis lipoxygenase domain containing protein 0.0042 0.0248 0.0242
Echinococcus multilocularis potassium voltage gated channel protein 0.0038 0.0205 0.0199
Echinococcus granulosus rhodopsin orphan GPCR 0.0209 0.1793 0.1787
Onchocerca volvulus 0.0038 0.0205 0.0675
Brugia malayi hypothetical protein 0.0209 0.1793 0.2822
Echinococcus multilocularis arachidonate 5 lipoxygenase 0.0185 0.1573 0.1568
Trichomonas vaginalis PIKK family atypical protein kinase 0.0029 0.0123 0.0419
Schistosoma mansoni opsin-like receptor 0.0209 0.1793 0.1932
Brugia malayi putative neuropeptide receptor NPR1 0.0209 0.1793 0.2822
Brugia malayi Voltage-gated potassium channel, Shaw-family (KCNC, Kv3-like) alpha-subunit. C. elegans egl-36 ortholog 0.0038 0.0205 0.0322
Schistosoma mansoni neuropeptide receptor 0.0209 0.1793 0.1932
Onchocerca volvulus 0.0209 0.1793 0.7902
Brugia malayi MH2 domain containing protein 0.0128 0.104 0.1637
Loa Loa (eye worm) hypothetical protein 0.0038 0.0205 0.0347
Echinococcus multilocularis tumor protein p63 0.0362 0.3206 0.3202
Echinococcus multilocularis tyrosine protein kinase Srms 0.0037 0.0202 0.0196
Giardia lamblia Thioredoxin reductase 0.0088 0.0675 0.2181
Echinococcus granulosus hypothetical protein 0.0947 0.8632 0.8631
Onchocerca volvulus DNA topoisomerase 2 homolog 0.0101 0.0793 0.3352
Trichomonas vaginalis PIKK family atypical protein kinase 0.0038 0.0211 0.0719
Trypanosoma cruzi apurinic/apyrimidinic endonuclease, putative 0.002 0.0043 0.0048
Onchocerca volvulus 0.0022 0.0057 0.0003
Loa Loa (eye worm) hypothetical protein 0.0209 0.1793 0.304
Loa Loa (eye worm) hypothetical protein 0.0652 0.5896 1
Brugia malayi hypothetical protein 0.0209 0.1793 0.2822
Echinococcus multilocularis Transcription factor, JmjC domain containing protein 0.0102 0.0803 0.0798
Echinococcus granulosus tyrosine protein kinase Src64B 0.0041 0.0239 0.0232
Mycobacterium ulcerans NADPH:adrenodoxin oxidoreductase FprB 0.0088 0.0675 0.2181
Echinococcus multilocularis RUN 0.0042 0.0248 0.0242
Echinococcus granulosus microtubule associated protein 2 0.0738 0.6697 0.6694
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0843 0.7666 1
Trypanosoma cruzi cytochrome P450, putative 0.0021 0.0049 0.0056
Schistosoma mansoni biogenic amine receptor 0.0209 0.1793 0.1932
Loa Loa (eye worm) hypothetical protein 0.0038 0.0205 0.0347
Echinococcus multilocularis isocitrate dehydrogenase 2 (NADP+) 0.0017 0.0014 0.0007
Toxoplasma gondii LsmAD domain-containing protein 0.0027 0.0107 0.0164
Loa Loa (eye worm) Sodium:neurotransmitter symporter family protein 0.0044 0.0264 0.0447
Echinococcus multilocularis calmodulin 0.0026 0.01 0.0093
Toxoplasma gondii calmodulin, putative 0.0026 0.01 0.0152
Schistosoma mansoni transient receptor potential cation channel subfamily m member 0.0038 0.0205 0.0215
Brugia malayi Bromodomain containing protein 0.0031 0.0146 0.0229
Loa Loa (eye worm) hypothetical protein 0.0031 0.0146 0.0247
Trichomonas vaginalis conserved hypothetical protein 0.0042 0.0244 0.0831
Trichomonas vaginalis PIKK family atypical protein kinase 0.0026 0.0098 0.0332
Echinococcus multilocularis potassium voltage gated channel subfamily D 0.0038 0.0205 0.0199
Mycobacterium ulcerans extragenic suppressor protein SuhB 0.004 0.0223 0.062
Toxoplasma gondii PHD-finger domain-containing protein 0.0031 0.0146 0.0233
Trichomonas vaginalis chromobox protein, putative 0.0045 0.0274 0.0931
Echinococcus granulosus PHD finger protein rhinoceros 0.0031 0.0146 0.014
Mycobacterium tuberculosis Probable NADPH:adrenodoxin oxidoreductase FprB (adrenodoxin reductase) (AR) (ferredoxin-NADP(+) reductase) 0.0088 0.0675 0.1166
Echinococcus multilocularis potassium voltage gated channel protein 0.0038 0.0205 0.0199
Loa Loa (eye worm) TK protein kinase 0.0033 0.0165 0.0279
Brugia malayi hypothetical protein 0.0071 0.0511 0.0803
Trichomonas vaginalis mercuric reductase, putative 0.0333 0.2939 1
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.0038 0.0205 0.0337
Schistosoma mansoni amine GPCR 0.0741 0.6717 0.7257
Schistosoma mansoni lipoxygenase 0.0109 0.087 0.0933
Brugia malayi hypothetical protein 0.0027 0.0107 0.0168
Trichomonas vaginalis PIKK family atypical protein kinase 0.0036 0.0188 0.0641
Echinococcus granulosus rhodopsin orphan GPCR 0.0209 0.1793 0.1787
Giardia lamblia NADH oxidase lateral transfer candidate 0.0333 0.2939 1
Trypanosoma cruzi isocitrate dehydrogenase, putative 0.0017 0.0014 0.0009
Echinococcus multilocularis g protein coupled receptor 0.0209 0.1793 0.1787
Loa Loa (eye worm) hypothetical protein 0.0209 0.1793 0.304
Mycobacterium ulcerans carbon monoxyde dehydrogenase small chain CoxS 0.0035 0.0185 0.0489
Schistosoma mansoni glutamate receptor kainate 0.0173 0.1462 0.1574
Loa Loa (eye worm) nuclear hormone receptor family member nhr-40 0.0022 0.0057 0.0097
Trypanosoma brucei dihydrolipoamide dehydrogenase 0.0843 0.7666 1
Toxoplasma gondii exonuclease III APE 0.002 0.0043 0.0053
Brugia malayi sulfakinin receptor protein 0.0209 0.1793 0.2822
Loa Loa (eye worm) hypothetical protein 0.0209 0.1793 0.304
Treponema pallidum hypothetical protein 0.0025 0.0087 0.015
Onchocerca volvulus 0.0044 0.0264 0.0942
Echinococcus granulosus FAD linked sulfhydryl oxidase ALR 0.0037 0.0197 0.0191
Onchocerca volvulus 0.0071 0.0511 0.2066
Echinococcus multilocularis voltage gated potassium channel 0.0046 0.0287 0.0281
Echinococcus multilocularis tyrosine protein kinase Fyn 0.0041 0.0239 0.0232
Trypanosoma cruzi Phosphatidylinositol 3-kinase tor1 0.0048 0.0302 0.0387
Brugia malayi Metabotropic glutamate receptor precursor. 0.0024 0.0083 0.013
Brugia malayi Heterochromatin protein 1 0.0075 0.0548 0.0862
Loa Loa (eye worm) hypothetical protein 0.0022 0.0057 0.0097
Echinococcus multilocularis Polycystic kidney disease protein 0.0042 0.0248 0.0242
Brugia malayi Augmenter of liver regeneration 0.0037 0.0197 0.031
Echinococcus granulosus GPCR family 2 0.0017 0.0013 0.0007
Echinococcus granulosus potassium voltage gated channel protein 0.0038 0.0205 0.0199
Onchocerca volvulus 0.0029 0.0124 0.0307
Trichomonas vaginalis set domain proteins, putative 0.0254 0.2211 0.7522
Trichomonas vaginalis PIKK family atypical protein kinase 0.0036 0.0188 0.0641
Schistosoma mansoni lipoxygenase 0.0185 0.1573 0.1694
Echinococcus granulosus alpha 1A adrenergic receptor 0.0209 0.1793 0.1787
Schistosoma mansoni sodium/chloride dependent neurotransmitter transporter 0.0044 0.0264 0.0278
Echinococcus multilocularis cadherin EGF LAG seven pass G type receptor 0.0017 0.0013 0.0007
Echinococcus granulosus uncharacterized sodium dependent transporter 0.0044 0.0264 0.0258
Loa Loa (eye worm) hypothetical protein 0.0209 0.1793 0.304
Loa Loa (eye worm) solute carrier family 6 member 4 0.0259 0.2254 0.3822
Mycobacterium ulcerans NADPH:adrenodoxin oxidoreductase FprA 0.0088 0.0675 0.2181
Mycobacterium leprae Probable fructose bisphosphate aldolase Fba 0.0153 0.1272 0.311
Schistosoma mansoni aminoadipate-semialdehyde dehydrogenase 0.0089 0.0681 0.073
Leishmania major myo-inositol-1(or 4)-monophosphatase 1, putative 0.004 0.0223 0.0283
Onchocerca volvulus Neuropeptide F receptor homolog 0.0209 0.1793 0.7902
Entamoeba histolytica disulphide oxidoreductase, putative 0.0088 0.0675 0.2331
Echinococcus multilocularis transient receptor potential gamma protein 0.0038 0.0205 0.0199
Brugia malayi Receptor family ligand binding region containing protein 0.003 0.0135 0.0212
Brugia malayi voltage-dependent calcium channel 0.0038 0.0205 0.0322
Echinococcus multilocularis pyroglutamylated rfamide peptide receptor 0.0209 0.1793 0.1787
Echinococcus granulosus jun protein 0.009 0.0689 0.0683
Echinococcus multilocularis nmda type glutamate receptor 0.0109 0.0865 0.0859
Mycobacterium tuberculosis Probable dehydrogenase 0.0199 0.1701 0.2973
Mycobacterium ulcerans thioredoxin reductase TrxB2 0.0088 0.0675 0.2181
Schistosoma mansoni adenoreceptor 0.0209 0.1793 0.1932
Mycobacterium ulcerans sugar phosphate isomerases/epimerases 0.0022 0.0057 0.0046
Echinococcus multilocularis potassium voltage gated channel protein 0.0038 0.0205 0.0199
Echinococcus granulosus nmda type glutamate receptor 0.0109 0.0865 0.0859
Brugia malayi DNA gyrase/topoisomerase IV, A subunit family protein 0.015 0.1242 0.1956
Plasmodium vivax ataxin-2 like protein, putative 0.0027 0.0107 0.0164
Schistosoma mansoni hypothetical protein 0.0181 0.1537 0.1655
Echinococcus granulosus mitogen activated protein kinase 0.0055 0.0362 0.0356
Loa Loa (eye worm) G-protein coupled receptor 0.0209 0.1793 0.304
Leishmania major target of rapamycin (TOR) kinase 2, putative 0.0048 0.0302 0.0387
Echinococcus multilocularis orexin receptor type 2 0.0209 0.1793 0.1787
Onchocerca volvulus 0.0044 0.0264 0.0942
Mycobacterium ulcerans carbon monoxyde dehydrogenase large chain CoxL 0.0087 0.0667 0.2152
Mycobacterium tuberculosis Probable carbon monoxyde dehydrogenase (medium chain) 0.0063 0.0437 0.0746
Schistosoma mansoni sodium/chloride dependent transporter 0.0259 0.2254 0.243
Toxoplasma gondii 4'-phosphopantetheinyl transferase domain-containing protein 0.0025 0.0089 0.0132
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0019 0.0035 0.0118
Mycobacterium tuberculosis Probable NADH dehydrogenase Ndh 0.0199 0.1701 0.2973
Onchocerca volvulus Calmodulin homolog 0.0026 0.01 0.0195
Mycobacterium ulcerans hypothetical protein 0.0022 0.0057 0.0046
Entamoeba histolytica dihydropyrimidine dehydrogenase, putative 0.0088 0.0675 0.2331
Loa Loa (eye worm) hypothetical protein 0.0041 0.0239 0.0405
Toxoplasma gondii pyridine nucleotide-disulfide oxidoreductase domain-containing protein 0.0088 0.0675 0.1166
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0033 0.0159 0.0165
Trypanosoma cruzi tyrosyl-DNA Phosphodiesterase (Tdp1), putative 0.0071 0.0511 0.0659
Trypanosoma brucei calmodulin 0.0026 0.01 0.0122
Brugia malayi Unidentified vitellogenin-linked transcript protein 6, putative 0.0209 0.1793 0.2822
Echinococcus granulosus pyridine nucleotide disulfide oxidoreductase 0.0088 0.0675 0.0669
Loa Loa (eye worm) hypothetical protein 0.0209 0.1793 0.304
Brugia malayi Glutamate receptor 1 precursor 0.0173 0.1462 0.2301
Leishmania major target of rapamycin (TOR) kinase 1, putative 0.0048 0.0302 0.0387
Toxoplasma gondii Erv1 / Alr family protein 0.0037 0.0197 0.0323
Schistosoma mansoni jun-related protein 0.0073 0.0533 0.057
Echinococcus granulosus neuropeptide receptor A26 0.0701 0.6352 0.635
Echinococcus granulosus COUP TF:Svp nuclear hormone receptor 0.0022 0.0057 0.0051
Trichomonas vaginalis glucosylceramidase, putative 0.0276 0.2417 0.8222
Trypanosoma brucei phosphatidylinositol 3-kinase tor, putative 0.0023 0.0068 0.008
Loa Loa (eye worm) hypothetical protein 0.0024 0.0083 0.014
Echinococcus granulosus adenylate cyclase 9 0.0083 0.0629 0.0623
Schistosoma mansoni opsin-like receptor 0.0209 0.1793 0.1932
Toxoplasma gondii NADH dehydrogenase (NDH2-II) 0.0088 0.0675 0.1166
Echinococcus granulosus hepatocyte nuclear factor 4 alpha 0.0022 0.0057 0.0051
Echinococcus multilocularis inositol monophosphatase 1 0.004 0.0223 0.0217
Echinococcus multilocularis rhodopsin orphan GPCR 0.0209 0.1793 0.1787
Echinococcus multilocularis hyperpolarization activated cyclic 0.0043 0.0253 0.0247
Echinococcus granulosus mitogen activated protein kinase 3 0.0055 0.0362 0.0356
Loa Loa (eye worm) hypothetical protein 0.0043 0.0253 0.0429
Loa Loa (eye worm) jmjC domain-containing protein 0.0064 0.0454 0.0769
Echinococcus multilocularis potassium voltage gated channel subfamily D 0.0038 0.0205 0.0199
Loa Loa (eye worm) hypothetical protein 0.0024 0.0083 0.014
Echinococcus multilocularis conserved hypothetical protein 0.0738 0.6697 0.6694
Echinococcus multilocularis 0.0049 0.0315 0.0308
Echinococcus multilocularis growth hormone secretagogue receptor type 1 0.0209 0.1793 0.1787
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0313 0.2754 0.9369
Echinococcus granulosus cpg binding protein 0.0032 0.0158 0.0152
Echinococcus multilocularis G-protein coupled receptor, putative 0.0209 0.1793 0.1787
Leishmania major 2,4-dienoyl-coa reductase fadh1, putative 0.0088 0.0675 0.0873
Echinococcus multilocularis tyrosyl DNA phosphodiesterase 1 0.0071 0.0511 0.0505
Onchocerca volvulus Steroid hormone receptor family member cnr14 homolog 0.0022 0.0057 0.0003
Echinococcus granulosus neuropeptide Y receptor 0.0209 0.1793 0.1787
Brugia malayi isocitrate dehydrogenase 0.0017 0.0014 0.0021
Toxoplasma gondii transporter, cation channel family protein 0.0038 0.0205 0.0337
Loa Loa (eye worm) TK/INSR protein kinase 0.0052 0.034 0.0576
Onchocerca volvulus 0.0029 0.0124 0.0307
Onchocerca volvulus 0.0209 0.1793 0.7902
Loa Loa (eye worm) hypothetical protein 0.0022 0.0057 0.0097
Trichomonas vaginalis disulfide oxidoreductase, putative 0.0088 0.0675 0.2297
Onchocerca volvulus 0.0045 0.0272 0.098
Echinococcus multilocularis voltage dependent calcium channel 0.0138 0.1133 0.1128
Trichomonas vaginalis voltage and ligand gated potassium channel, putative 0.0043 0.0253 0.0862
Plasmodium falciparum ataxin-2 like protein, putative 0.0027 0.0107 0.0164
Schistosoma mansoni thyroid hormone receptor 0.0022 0.0057 0.0055
Echinococcus granulosus sodium leak channel non selective protein 0.0038 0.0205 0.0199
Onchocerca volvulus 0.0088 0.0675 0.2815
Echinococcus multilocularis chromobox protein 1 0.0075 0.0548 0.0541
Echinococcus granulosus tyrosine protein kinase Fyn 0.0041 0.0239 0.0232
Schistosoma mansoni tyrosine kinase 0.0026 0.0102 0.0103
Schistosoma mansoni sulfide quinone reductase 0.0088 0.0675 0.0723
Plasmodium vivax calmodulin, putative 0.0026 0.01 0.0152
Schistosoma mansoni voltage-gated potassium channel 0.0038 0.0205 0.0215
Trypanosoma brucei hypothetical protein, conserved 0.0088 0.0675 0.0873
Loa Loa (eye worm) hypothetical protein 0.0044 0.0264 0.0447
Trichomonas vaginalis dihydropyrimidine dehydrogenase, putative 0.0088 0.0675 0.2297
Brugia malayi Guanylyl cyclase protein 23 0.003 0.0135 0.0212
Echinococcus granulosus pyroglutamylated rfamide peptide receptor 0.0209 0.1793 0.1787
Trichomonas vaginalis disulfide oxidoreductase, putative 0.0088 0.0675 0.2297
Loa Loa (eye worm) hypothetical protein 0.0209 0.1793 0.304
Echinococcus multilocularis mitogen activated protein kinase 0.0055 0.0362 0.0356
Brugia malayi steroid hormone receptor 0.0022 0.0057 0.009
Schistosoma mansoni calcium-activated potassium channel 0.0038 0.0205 0.0215
Schistosoma mansoni DNA topoisomerase II 0.015 0.1242 0.1337
Echinococcus multilocularis tyrosine protein kinase lyn lyn a protein tyrosine kinase lymphocyte specific protein tyrosine kinase 0.0041 0.0239 0.0232
Echinococcus granulosus dro:myosuppressin receptor 0.0209 0.1793 0.1787
Schistosoma mansoni jumonji/arid domain-containing protein 0.004 0.0223 0.0234
Echinococcus multilocularis ryanodine receptor 44f 0.0038 0.0205 0.0199
Loa Loa (eye worm) intermediate filament protein 0.0029 0.0124 0.021
Brugia malayi jmjC domain containing protein 0.004 0.0223 0.0351
Onchocerca volvulus Protein ultraspiracle homolog 0.0022 0.0057 0.0003
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0209 0.1793 0.1932
Mycobacterium tuberculosis DNA gyrase (subunit A) GyrA (DNA topoisomerase (ATP-hydrolysing)) (DNA topoisomerase II) (type II DNA topoisomerase) 0.0032 0.0155 0.0249
Schistosoma mansoni nuclear receptor 2DBD-gamma 0.0022 0.0057 0.0055
Leishmania major 2,4-dienoyl-coa reductase-like protein 0.0088 0.0675 0.0873
Mycobacterium tuberculosis holo-[acyl-carrier protein] synthase AcpS (holo-ACP synthase) (CoA:APO-[ACP]pantetheinephosphotransferase) (CoA:APO-[acyl-carrie 0.0025 0.0089 0.0132
Trichomonas vaginalis glucosylceramidase, putative 0.0276 0.2417 0.8222
Trichomonas vaginalis glutamate synthase, putative 0.0088 0.0675 0.2297
Echinococcus multilocularis cpg binding protein 0.0032 0.0158 0.0152
Onchocerca volvulus 0.0042 0.0248 0.087
Mycobacterium ulcerans aerobic-type carbon monoxide dehydrogenase subunit CoxM_2 0.0063 0.0437 0.1359
Entamoeba histolytica protein kinase, putative 0.0033 0.0165 0.0448
Schistosoma mansoni Tr4/Tr2 (homologue) 0.0022 0.0057 0.0055
Schistosoma mansoni voltage-gated potassium channel 0.0078 0.058 0.062
Schistosoma mansoni voltage-gated potassium channel 0.0038 0.0205 0.0215
Schistosoma mansoni transient receptor potential channel 4 0.0038 0.0205 0.0215
Trypanosoma cruzi Present in the outer mitochondrial membrane proteome 4 0.0037 0.0197 0.0249
Plasmodium vivax SET domain protein, putative 0.0033 0.0159 0.0256
Toxoplasma gondii hypothetical protein 0.0044 0.0264 0.0441
Mycobacterium ulcerans DNA gyrase subunit A 0.0032 0.0155 0.0385
Echinococcus granulosus diuretic hormone 44 receptor GPRdih2 0.0017 0.0013 0.0007
Schistosoma mansoni voltage-gated potassium channel 0.0038 0.0205 0.0215
Onchocerca volvulus Transient receptor potential cation channel trpm homolog 0.0038 0.0205 0.0675
Echinococcus granulosus tyrosine kinase 0.0026 0.0102 0.0095
Schistosoma mansoni transient receptor potential cation channel subfamily m member 0.0038 0.0205 0.0215
Onchocerca volvulus 0.0031 0.0142 0.0386
Loa Loa (eye worm) cyclic-nucleotide gated cation channel 0.0043 0.0253 0.0429
Brugia malayi Nuclear hormone receptor family member nhr-3 0.0022 0.0057 0.009
Echinococcus granulosus ecdysone induced protein 78C 0.0022 0.0057 0.0051
Trichomonas vaginalis glucosylceramidase, putative 0.0276 0.2417 0.8222
Echinococcus granulosus allatostatin A receptor 0.0209 0.1793 0.1787
Schistosoma mansoni norepinephrine/norepinephrine transporter 0.0259 0.2254 0.243
Brugia malayi G-protein coupled receptor 0.0209 0.1793 0.2822
Schistosoma mansoni ancient conserved domain protein 2 (cyclin m2) 0.0209 0.1793 0.1932
Loa Loa (eye worm) hypothetical protein 0.0044 0.0264 0.0447
Echinococcus multilocularis g protein linked acetylcholine receptor gar 2a 0.0209 0.1793 0.1787
Echinococcus granulosus thyrotropin releasing hormone receptor 0.0209 0.1793 0.1787
Mycobacterium ulcerans 4'-phosphopantetheinyl transferase 0.0025 0.0089 0.0157
Trypanosoma brucei tyrosyl-DNA Phosphodiesterase (Tdp1), putative 0.0071 0.0511 0.0659
Echinococcus multilocularis g protein linked acetylcholine receptor gar 2a 0.0209 0.1793 0.1787
Loa Loa (eye worm) hypothetical protein 0.0209 0.1793 0.304
Echinococcus granulosus 3'partial|tyrosine protein kinase Fgr 0.0041 0.0239 0.0232
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0019 0.0033 0.0029
Loa Loa (eye worm) hypothetical protein 0.0209 0.1793 0.304
Schistosoma mansoni tyrosine kinase 0.0087 0.0662 0.0709
Trypanosoma brucei pyridine nucleotide-disulphide oxidoreductase, putative 0.0088 0.0675 0.0873
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.1095 1 1
Toxoplasma gondii hypothetical protein 0.0038 0.0205 0.0337
Mycobacterium ulcerans flavoprotein disulfide reductase 0.0333 0.2939 1
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0022 0.0057 0.009
Schistosoma mansoni sodium/chloride dependent transporter 0.0044 0.0264 0.0278
Loa Loa (eye worm) hypothetical protein 0.0053 0.0347 0.0589
Brugia malayi exodeoxyribonuclease III family protein 0.002 0.0043 0.0068
Echinococcus multilocularis transient receptor potential cation channel 0.0038 0.0205 0.0199
Trypanosoma cruzi hypothetical protein, conserved 0.0088 0.0675 0.0873
Trypanosoma cruzi calmodulin 0.0026 0.01 0.0122
Loa Loa (eye worm) hypothetical protein 0.0209 0.1793 0.304
Schistosoma mansoni transient receptor potential channel 0.0038 0.0205 0.0215
Brugia malayi neuropeptide F receptor 0.0209 0.1793 0.2822
Onchocerca volvulus Heterochromatin protein 1 homolog 0.0045 0.0274 0.0986
Brugia malayi Voltage-gated potassium channel, Shaw-family (KCNC, Kv3-like) alpha-subunit 0.0038 0.0205 0.0322
Echinococcus granulosus retinoic acid receptor rxr beta a 0.0022 0.0057 0.0051
Brugia malayi Nuclear hormone receptor family member nhr-41 0.0022 0.0057 0.009
Entamoeba histolytica DNA topoisomerase II, putative 0.015 0.1242 0.4424
Brugia malayi hypothetical protein 0.0044 0.0264 0.0415
Echinococcus granulosus tachykinin peptides receptor 99D 0.0209 0.1793 0.1787
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0022 0.0057 0.0051
Echinococcus granulosus tm gpcr rhodopsin 0.0209 0.1793 0.1787
Trichomonas vaginalis glucosylceramidase, putative 0.0181 0.1537 0.5228
Trypanosoma brucei calmodulin 0.0026 0.01 0.0122
Onchocerca volvulus 0.0209 0.1793 0.7902
Loa Loa (eye worm) pigment dispersing factor receptor c 0.0053 0.0351 0.0595
Plasmodium falciparum glutathione reductase 0.0333 0.2939 0.5155
Echinococcus granulosus calmodulin 0.0026 0.01 0.0093
Loa Loa (eye worm) hypothetical protein 0.0038 0.0205 0.0347
Brugia malayi G protein-coupled receptor F59B2.13 0.0209 0.1793 0.2822
Echinococcus granulosus voltage dependent calcium channel type d subunit|voltage dependent calcium channel alpha 1 0.0138 0.1133 0.1128
Echinococcus granulosus biogenic amine 5HT receptor 0.1015 0.9254 0.9253
Loa Loa (eye worm) TK/EGFR protein kinase 0.0161 0.1346 0.2282
Echinococcus granulosus peregrin 0.0031 0.0146 0.014
Loa Loa (eye worm) programmed cell death 8 0.0088 0.0675 0.1145
Mycobacterium tuberculosis Probable exodeoxyribonuclease III protein XthA (exonuclease III) (EXO III) (AP endonuclease VI) 0.002 0.0043 0.0053
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0209 0.1793 0.1932
Trypanosoma cruzi 2,4-dienoyl-coa reductase fadh1, putative 0.0088 0.0675 0.0873
Toxoplasma gondii 4'-phosphopantetheinyl transferase superfamily protein 0.0025 0.0089 0.0132
Trichomonas vaginalis PIKK family atypical protein kinase 0.0038 0.0211 0.0719
Onchocerca volvulus 0.0209 0.1793 0.7902
Echinococcus multilocularis lamin dm0 0.0029 0.0124 0.0118
Echinococcus multilocularis voltage dependent calcium channel type d subunit 0.0138 0.1133 0.1128
Echinococcus multilocularis rhodopsin orphan GPCR 0.0209 0.1793 0.1787
Echinococcus multilocularis jun protein 0.009 0.0689 0.0683
Trypanosoma brucei Voltage-dependent calcium channel subunit, putative 0.0098 0.076 0.0984
Loa Loa (eye worm) hypothetical protein 0.0024 0.0083 0.014
Echinococcus multilocularis allatostatin A receptor 0.0209 0.1793 0.1787
Brugia malayi ion channel NompC 0.0038 0.0205 0.0322
Loa Loa (eye worm) voltage-dependent calcium channel 0.0057 0.038 0.0645
Loa Loa (eye worm) hypothetical protein 0.0019 0.0032 0.0055
Trichomonas vaginalis xanthine dehydrogenase, putative 0.0185 0.1574 0.5357
Echinococcus granulosus metabotropic glutamate receptor 5 0.0024 0.0083 0.0077

Activities

Activity type Activity value Assay description Source Reference
HSF (functional) = 0 ml HSF produced by bone marrow-derived stromal cell lines C6.4 on stimulation with the compound at (1000 ng/mL) was determined in vitro in an GM-CFC assay. ChEMBL. 9288169

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
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External resources for this compound

No external resources registered for this compound

Bibliographic References

1 literature reference was collected for this gene.

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