Detailed information for compound 401730

Basic information

Technical information
  • Name: Unnamed compound
  • MW: 1011 | Formula: C41H62N12O18
  • H donors: 16 H acceptors: 20 LogP: -9.47 Rotable bonds: 23
    Rule of 5 violations (Lipinski): 4
  • SMILES: NCCCCC[C@@H](C(=O)O)NC(=O)[C@@H]1CCCC[C@H](NC(=O)[C@@H](CC(=O)O)NC(=O)[C@@H](CO)NC(=O)c2c(C(=O)N[C@H](C(=O)N[C@@H](C(=O)N1)CC(=O)O)CO)nccn2)C(=O)N[C@H](C(=O)O)CCCCN
  • InChi: 1S/C41H62N12O18/c42-12-6-1-2-10-22(40(68)69)48-32(60)20-8-3-4-9-21(33(61)49-23(41(70)71)11-5-7-13-43)47-35(63)25(17-29(58)59)51-37(65)27(19-55)53-39(67)31-30(44-14-15-45-31)38(66)52-26(18-54)36(64)50-24(16-28(56)57)34(62)46-20/h14-15,20-27,54-55H,1-13,16-19,42-43H2,(H,46,62)(H,47,63)(H,48,60)(H,49,61)(H,50,64)(H,51,65)(H,52,66)(H,53,67)(H,56,57)(H,58,59)(H,68,69)(H,70,71)/t20-,21-,22-,23-,24+,25+,26-,27+/m0/s1
  • InChiKey: WVKFKVOSPQQOIE-XEOJPQTASA-N  

Network

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Synonyms

No synonyms found for this compound

Targets

Known targets for this compound

No curated genes were found associated with this compound

Predicted pathogen targets for this compound

By orthology
No druggable targets predicted by orthology data
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity

Obtained from network model

Ranking Plot


Putative Targets List


Species Potential target Raw Global Species
Onchocerca volvulus 0.0254 0.2213 0.9817
Plasmodium vivax NAD(P)H-dependent glutamate synthase, putative 0.0088 0.0675 0.1166
Onchocerca volvulus Adenylate cyclase type 3 homolog 0.0231 0.1997 0.8833
Echinococcus multilocularis calmodulin 0.0026 0.01 0.0093
Brugia malayi Thioredoxin reductase 0.063 0.5689 0.8955
Loa Loa (eye worm) ryanodine receptor 0.0038 0.0205 0.0347
Loa Loa (eye worm) hypothetical protein 0.0082 0.0617 0.1046
Brugia malayi Voltage-gated potassium channel, EAG (KCNH1)-related. C. elegans egl-2 ortholog 0.0046 0.0287 0.0451
Schistosoma mansoni cpg binding protein 0.0032 0.0158 0.0164
Echinococcus multilocularis glutamate receptor, ionotrophic, AMPA 3 0.0198 0.1688 0.1682
Schistosoma mansoni cyclic-nucleotide-gated cation channel 0.0043 0.0253 0.0267
Loa Loa (eye worm) hypothetical protein 0.0038 0.0205 0.0347
Loa Loa (eye worm) RGC/RGC protein kinase 0.003 0.0135 0.0228
Schistosoma mansoni inositol monophosphatase 0.004 0.0223 0.0234
Schistosoma mansoni cyclic-nucleotide-gated cation channel 0.0043 0.0253 0.0267
Chlamydia trachomatis DNA gyrase subunit A 0.0032 0.0155 0.0232
Schistosoma mansoni glutamate receptor AMPA 0.0173 0.1462 0.1574
Echinococcus multilocularis glutamate receptor 2 0.0198 0.1688 0.1682
Echinococcus granulosus glutamate receptor 2 0.0198 0.1688 0.1682
Brugia malayi Nuclear hormone receptor family member nhr-1 0.0022 0.0057 0.009
Brugia malayi alpha keto acid dehydrogenase complex, E3 component, lipoamide dehydrogenase 0.0244 0.2121 0.3339
Trichomonas vaginalis PIKK family atypical protein kinase 0.0038 0.0211 0.0719
Trichomonas vaginalis voltage and ligand gated potassium channel, putative 0.0043 0.0253 0.0862
Wolbachia endosymbiont of Brugia malayi thioredoxin reductase 0.0088 0.0675 0.2181
Schistosoma mansoni sodium-dependent amino acid transporter 0.0044 0.0264 0.0278
Echinococcus granulosus dihydropyrimidine dehydrogenase NADP 0.0088 0.0675 0.0669
Echinococcus granulosus glutamate NMDA receptor subunit 0.035 0.3103 0.3099
Trypanosoma brucei hypothetical protein, conserved 0.0025 0.0089 0.0108
Plasmodium vivax glutathione reductase, putative 0.063 0.5689 1
Giardia lamblia Fructose-bisphosphate aldolase 0.0313 0.2754 0.936
Brugia malayi NADPH:adrenodoxin oxidoreductase, mitochondrial precursor 0.0088 0.0675 0.1063
Toxoplasma gondii hypothetical protein 0.0044 0.0264 0.0441
Schistosoma mansoni chromobox protein 0.0075 0.0548 0.0585
Echinococcus multilocularis G protein coupled 5 hydroxytryptamine receptor 0.0209 0.1793 0.1787
Onchocerca volvulus 0.0209 0.1793 0.7902
Plasmodium falciparum LCCL domain-containing protein 0.0042 0.0248 0.0413
Echinococcus granulosus potassium voltage gated channel subfamily D 0.0038 0.0205 0.0199
Echinococcus granulosus neuropeptides capa receptor 0.0209 0.1793 0.1787
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0022 0.0057 0.0051
Trypanosoma cruzi extracellular receptor, putative 0.0024 0.0083 0.01
Echinococcus multilocularis shaker cognate 0.0038 0.0205 0.0199
Loa Loa (eye worm) hypothetical protein 0.0209 0.1793 0.304
Schistosoma mansoni transient receptor potential channel 0.0038 0.0205 0.0215
Loa Loa (eye worm) hypothetical protein 0.047 0.4207 0.7134
Loa Loa (eye worm) unidentified vitellogenin-linked transcript protein 6 0.0209 0.1793 0.304
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0313 0.2754 0.9369
Trichomonas vaginalis PIKK family atypical protein kinase 0.0028 0.0121 0.041
Loa Loa (eye worm) nuclear hormone receptor family member nhr-1 0.0022 0.0057 0.0097
Echinococcus multilocularis sodium and chloride dependent glycine 0.0044 0.0264 0.0258
Trypanosoma brucei dihydrolipoamide dehydrogenase, point mutation 0.0656 0.593 0.7734
Schistosoma mansoni tyrosine kinase 0.0041 0.0239 0.0251
Echinococcus multilocularis ecdysone induced protein 78C 0.0022 0.0057 0.0051
Echinococcus multilocularis insulin receptor 0.0052 0.034 0.0334
Brugia malayi cation channel family protein 0.0038 0.0205 0.0322
Echinococcus multilocularis Glutamate receptor, ionotropic kainate 3 0.0115 0.0918 0.0912
Trichomonas vaginalis disulfide oxidoreductase, putative 0.0088 0.0675 0.2297
Schistosoma mansoni steroid hormone receptor ad4bp 0.0022 0.0057 0.0055
Echinococcus multilocularis short transient receptor potential channel 6 0.0038 0.0208 0.0201
Brugia malayi glutathione reductase 0.063 0.5689 0.8955
Echinococcus multilocularis survival motor neuron protein 1 0.0253 0.2201 0.2196
Loa Loa (eye worm) inositol-1 0.004 0.0223 0.0378
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0209 0.1793 0.1932
Leishmania major trypanothione reductase 0.063 0.5689 0.7419
Echinococcus granulosus neuropeptide Y receptor 0.0209 0.1793 0.1787
Loa Loa (eye worm) hypothetical protein 0.0061 0.0421 0.0713
Schistosoma mansoni hypothetical protein 0.0017 0.0013 0.0008
Schistosoma mansoni neuropeptide receptor 0.0209 0.1793 0.1932
Brugia malayi hypothetical protein 0.0253 0.2201 0.3464
Trypanosoma cruzi Phosphatidylinositol 3-kinase tor2 0.0048 0.0302 0.0387
Entamoeba histolytica hypothetical protein 0.0025 0.0089 0.0167
Brugia malayi G-protein coupled receptor 0.0209 0.1793 0.2822
Mycobacterium leprae PROBABLE NADPH:ADRENODOXIN OXIDOREDUCTASE FPRB (ADRENODOXIN REDUCTASE) (AR) (FERREDOXIN-NADP(+) REDUCTASE) 0.0088 0.0675 0.1582
Leishmania major tyrosyl-DNA phosphodiesterase 1 0.0071 0.0511 0.0659
Echinococcus granulosus 7TM GPCR rhodopsin 0.0209 0.1793 0.1787
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0843 0.7666 1
Echinococcus multilocularis voltage dependent calcium channel 0.0138 0.1133 0.1128
Loa Loa (eye worm) hypothetical protein 0.0228 0.1964 0.3331
Echinococcus multilocularis rhodopsin orphan GPCR 0.0209 0.1793 0.1787
Brugia malayi Nuclear hormone receptor family member nhr-40 0.0022 0.0057 0.009
Trichomonas vaginalis glutathione reductase, putative 0.0333 0.2939 1
Echinococcus granulosus insulin growth factor 1 receptor beta 0.0052 0.034 0.0334
Trypanosoma cruzi NADPH:adrenodoxin oxidoreductase, mitochondrial, putative 0.0088 0.0675 0.0873
Echinococcus multilocularis alpha 1A adrenergic receptor 0.0209 0.1793 0.1787
Trichomonas vaginalis calmodulin, putative 0.0026 0.01 0.034
Echinococcus granulosus Ribosomal protein S1 RNA binding domain 0.0074 0.0543 0.0537
Toxoplasma gondii pyruvate dehydrogenase complex subunit PDH-E3II 0.0333 0.2939 0.5155
Onchocerca volvulus Dual oxidase homolog 0.0078 0.0577 0.2369
Brugia malayi Serotonin/octopamine receptor family protein 7 0.0525 0.4724 0.7436
Trichomonas vaginalis glucosylceramidase, putative 0.0181 0.1537 0.5228
Brugia malayi photoreceptor-specific nuclear receptor 0.0022 0.0057 0.009
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.0038 0.0205 0.0337
Mycobacterium tuberculosis NADPH-dependent mycothiol reductase Mtr 0.063 0.5689 1
Loa Loa (eye worm) hypothetical protein 0.0024 0.0083 0.014
Wolbachia endosymbiont of Brugia malayi thioredoxin reductase 0.0088 0.0675 0.2181
Leishmania major mitogen activated protein kinase, putative,map kinase, putative 0.0055 0.0362 0.0464
Plasmodium vivax dihydrolipoyl dehydrogenase, mitochondrial, putative 0.0333 0.2939 0.5155
Echinococcus granulosus tyrosyl DNA phosphodiesterase 1 0.0071 0.0511 0.0505
Toxoplasma gondii Sodium:neurotransmitter symporter family protein 0.0044 0.0264 0.0441
Schistosoma mansoni transient receptor potential cation channel subfamily m member 0.0038 0.0205 0.0215
Loa Loa (eye worm) hypothetical protein 0.0044 0.0264 0.0447
Echinococcus multilocularis insulin growth factor 1 receptor beta 0.0052 0.034 0.0334
Toxoplasma gondii selenide, water dikinase 0.0088 0.0675 0.1166
Echinococcus granulosus tyrosine protein kinase Lyn 0.0042 0.0243 0.0237
Echinococcus granulosus histone lysine methyltransferase setb 0.0033 0.0159 0.0153
Echinococcus granulosus voltage gated sodium channel Nav1 alpha subunit 0.0497 0.4457 0.4453
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0022 0.0057 0.009
Trypanosoma cruzi calmodulin, putative 0.0026 0.01 0.0122
Loa Loa (eye worm) hypothetical protein 0.0017 0.0013 0.0022
Schistosoma mansoni transient receptor potential channel 0.0038 0.0208 0.0217
Echinococcus granulosus peptide allatostatin:somatostatin 0.0209 0.1793 0.1787
Mycobacterium ulcerans hypothetical protein 0.003 0.0136 0.032
Chlamydia trachomatis DNA gyrase subunit B 0.0087 0.0665 0.2021
Echinococcus granulosus sulfide:quinone oxidoreductase 0.0088 0.0675 0.0669
Loa Loa (eye worm) exodeoxyribonuclease III family protein 0.002 0.0043 0.0073
Loa Loa (eye worm) hypothetical protein 0.0022 0.0057 0.0097
Echinococcus granulosus glutamate receptor ionotropic kainate 3 0.0074 0.0543 0.0537
Echinococcus granulosus epidermal growth factor receptor 0.0161 0.1346 0.134
Plasmodium falciparum FAD-linked sulfhydryl oxidase ERV1, putative 0.0037 0.0197 0.0323
Echinococcus granulosus epidermal growth factor receptor 0.0087 0.0662 0.0656
Mycobacterium ulcerans aerobic-type carbon monoxide dehydrogenase subunit CoxL_2 0.0087 0.0667 0.2152
Loa Loa (eye worm) hypothetical protein 0.0053 0.0352 0.0597
Echinococcus granulosus two pore calcium channel protein 2 0.0038 0.0205 0.0199
Schistosoma mansoni peptide (allatostatin)-like receptor 0.0209 0.1793 0.1932
Onchocerca volvulus 0.0026 0.01 0.0194
Schistosoma mansoni serine/threonine protein kinase 0.0055 0.0362 0.0385
Echinococcus multilocularis epidermal growth factor receptor 0.0087 0.0662 0.0656
Schistosoma mansoni biogenic amine (octopamine/dopamine) receptor 0.0525 0.4724 0.5101
Onchocerca volvulus 0.003 0.0135 0.0354
Echinococcus granulosus serotonin transporter 0.0259 0.2254 0.2249
Giardia lamblia PHD finger protein 15 0.0031 0.0146 0.0354
Brugia malayi hypothetical protein 0.0042 0.0248 0.039
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0033 0.0159 0.0165
Brugia malayi Voltage-gated calcium channel, T-type, alpha subunit. C. elegans cca-1 ortholog 0.0038 0.0205 0.0322
Schistosoma mansoni nuclear hormone receptor 0.0022 0.0057 0.0055
Treponema pallidum sodium- and chloride- dependent transporter 0.0259 0.2254 0.7632
Echinococcus multilocularis receptor type guanylyl cyclase 0.003 0.0135 0.0128
Entamoeba histolytica phosphatidylinositol3-kinaseTor2, putative 0.0048 0.0302 0.0956
Echinococcus multilocularis tyrosine protein kinase Blk 0.0037 0.0202 0.0196
Echinococcus multilocularis dihydrolipoamide dehydrogenase 0.0333 0.2939 0.2935
Mycobacterium ulcerans carbon monoxyde dehydrogenase large chain CoxL 0.0055 0.0366 0.1114
Loa Loa (eye worm) hypothetical protein 0.0209 0.1793 0.304
Echinococcus granulosus inositol monophosphatase 1 0.004 0.0223 0.0217
Onchocerca volvulus DNA topoisomerase 2 homolog 0.0101 0.0793 0.3352
Leishmania major calmodulin, putative 0.0026 0.01 0.0122
Schistosoma mansoni RAR-like nuclear receptor 0.0022 0.0057 0.0055
Mycobacterium leprae possible inositol monophosphatase SubH (IMPase) (inositol-1-phosphatase) (I-1-Pase ). 0.0035 0.0185 0.0327
Brugia malayi hypothetical protein 0.0042 0.0248 0.039
Loa Loa (eye worm) hypothetical protein 0.0038 0.0205 0.0347
Echinococcus multilocularis potassium voltage gated channel subfamily A 0.0038 0.0205 0.0199
Schistosoma mansoni chromobox protein 0.0075 0.0548 0.0585
Chlamydia trachomatis thioredoxin reductase 0.0088 0.0675 0.2057
Echinococcus granulosus DNA topoisomerase 2 alpha 0.015 0.1242 0.1237
Trypanosoma brucei protein kinase, putative 0.0055 0.0362 0.0464
Echinococcus multilocularis serotonin receptor 0.047 0.4207 0.4203
Trichomonas vaginalis myo inositol monophosphatase, putative 0.004 0.0223 0.0759
Echinococcus granulosus tyrosine protein kinase Fyn 0.0041 0.0239 0.0232
Echinococcus multilocularis glutamate receptor 2 0.0173 0.1462 0.1456
Entamoeba histolytica FKBP-rapamycin associated protein (FRAP), putative 0.0048 0.0302 0.0956
Schistosoma mansoni ATP-binding cassette transporter 0.0174 0.1464 0.1577
Echinococcus multilocularis g protein coupled receptor 0.0209 0.1793 0.1787
Trichomonas vaginalis disulfide oxidoreductase, putative 0.0088 0.0675 0.2297
Echinococcus granulosus receptor type guanylyl cyclase 0.003 0.0135 0.0128
Echinococcus multilocularis NADP dependent isocitrate dehydrogenase 0.0017 0.0014 0.0007
Schistosoma mansoni voltage-gated potassium channel 0.0038 0.0205 0.0215
Trypanosoma brucei DNA topoisomerase ii 0.0168 0.1412 0.1835
Chlamydia trachomatis dihydrolipoyl dehydrogenase 0.0333 0.2939 1
Trypanosoma cruzi pyridine nucleotide-disulphide oxidoreductase, putative 0.0088 0.0675 0.0873
Loa Loa (eye worm) nuclear hormone receptor family member nhr-31 0.0022 0.0057 0.0097
Echinococcus granulosus neuropeptide receptor 0.0209 0.1793 0.1787
Echinococcus multilocularis tyrosine protein kinase Src42A 0.0035 0.0183 0.0177
Trichomonas vaginalis chromobox protein, putative 0.0075 0.0548 0.1863
Treponema pallidum DNA gyrase, subunit B (gyrB) 0.0087 0.0665 0.2146
Loa Loa (eye worm) glutathione reductase 0.063 0.5689 0.9648
Schistosoma mansoni high voltage-activated calcium channel Cav2A 0.0138 0.1133 0.1219
Plasmodium falciparum ferrodoxin reductase-like protein 0.0088 0.0675 0.1166
Onchocerca volvulus 0.0259 0.2254 1
Schistosoma mansoni sodium/chloride dependent neurotransmitter transporter 0.0044 0.0264 0.0278
Treponema pallidum amino acid ABC transporter, periplasmic binding protein (hisJ) 0.004 0.0232 0.065
Brugia malayi Doublecortin family protein 0.0042 0.0248 0.039
Echinococcus granulosus G protein coupled receptor 139 0.0209 0.1793 0.1787
Echinococcus granulosus cyclic nucleotide gated cation channel 0.0043 0.0253 0.0247
Echinococcus multilocularis glutamate receptor NMDA 0.0084 0.0639 0.0633
Loa Loa (eye worm) steroid hormone receptor 0.0022 0.0057 0.0097
Giardia lamblia Calmodulin 0.0026 0.01 0.0194
Echinococcus granulosus tyrosine kinase 0.0037 0.0202 0.0196
Echinococcus granulosus tyrosine kinase|tyrosine protein kinase Fyn 0.0037 0.0202 0.0196
Echinococcus multilocularis FKBP12 rapamycin complex associated protein 0.0048 0.0302 0.0296
Brugia malayi calcium-independent alpha-latrotoxin receptor 2, putative 0.0017 0.0013 0.0021
Onchocerca volvulus 0.0209 0.1793 0.7902
Loa Loa (eye worm) G-protein-linked acetylcholine receptor protein 2 0.0209 0.1793 0.304
Schistosoma mansoni metabotropic glutamate receptor 0.0024 0.0083 0.0083
Schistosoma mansoni voltage-gated potassium channel 0.0038 0.0205 0.0215
Trypanosoma cruzi Voltage-dependent calcium channel subunit, putative 0.0098 0.076 0.0984
Loa Loa (eye worm) G-protein coupled receptor 0.0209 0.1793 0.304
Leishmania major extracellular receptor, putative 0.0024 0.0083 0.01
Trypanosoma cruzi tyrosyl-DNA Phosphodiesterase (Tdp1), putative 0.0071 0.0511 0.0659
Trypanosoma brucei inositol-1(or 4)-monophosphatase 1, putative 0.004 0.0223 0.0283
Brugia malayi Pre-SET motif family protein 0.0223 0.1926 0.3032
Trypanosoma brucei isocitrate dehydrogenase, putative 0.0017 0.0014 0.0009
Loa Loa (eye worm) hypothetical protein 0.0394 0.3507 0.5947
Brugia malayi F/Y-rich N-terminus family protein 0.0021 0.0049 0.0077
Trichomonas vaginalis PIKK family atypical protein kinase 0.0036 0.0188 0.0641
Echinococcus multilocularis hepatocyte nuclear factor 4 alpha 0.0022 0.0057 0.0051
Brugia malayi Isocitrate dehydrogenase 0.0017 0.0014 0.0021
Trichomonas vaginalis PIKK family atypical protein kinase 0.0029 0.0123 0.0419
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0019 0.0035 0.0118
Schistosoma mansoni retinoic acid receptor RXR 0.0022 0.0057 0.0055
Trichomonas vaginalis glucosylceramidase, putative 0.0276 0.2417 0.8222
Echinococcus granulosus calcium activated potassium channel 0.0038 0.021 0.0203
Echinococcus granulosus potassium voltage gated channel subfamily D 0.0038 0.0205 0.0199
Schistosoma mansoni rab6-interacting 0.0042 0.0248 0.0261
Mycobacterium tuberculosis Probable endonuclease IV End (endodeoxyribonuclease IV) (apurinase) 0.0082 0.0617 0.1063
Trypanosoma brucei NADH dehydrogenase 0.0088 0.0675 0.0873
Echinococcus multilocularis histone lysine N methyltransferase SETMAR 0.0033 0.0159 0.0153
Trichomonas vaginalis apoptosis inducing factor, putative 0.0088 0.0675 0.2297
Trypanosoma brucei mitogen activated protein kinase 4, putative 0.0055 0.0362 0.0464
Plasmodium falciparum dihydrolipoyl dehydrogenase, apicoplast 0.0333 0.2939 0.5155
Loa Loa (eye worm) TYRA-2 protein 0.0209 0.1793 0.304
Loa Loa (eye worm) follicle stimulating hormone receptor 0.0209 0.1793 0.304
Leishmania major hypothetical protein, conserved 0.0027 0.0107 0.0131
Toxoplasma gondii non-proton pumping type-II NADH dehydrogenase I 0.0088 0.0675 0.1166
Loa Loa (eye worm) glutamate receptor 0.0024 0.0083 0.014
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0656 0.593 0.7734
Toxoplasma gondii Sodium:neurotransmitter symporter family protein 0.0044 0.0264 0.0441
Schistosoma mansoni neuropeptide receptor 0.0209 0.1793 0.1932
Brugia malayi Transient-receptor-potential like protein 0.0038 0.0205 0.0322
Echinococcus multilocularis tyrosine protein kinase Fyn 0.0041 0.0239 0.0232
Echinococcus multilocularis metabotropic glutamate receptor 5 0.0024 0.0083 0.0077
Leishmania major 2-oxoglutarate dehydrogenase, e3 component, lipoamidedehydrogenase-like protein 0.0731 0.6626 0.8642
Loa Loa (eye worm) CMGC/MAPK/ERK1 protein kinase 0.0055 0.0362 0.0614
Echinococcus multilocularis potassium voltage gated channel subfamily H 0.0074 0.0547 0.054
Loa Loa (eye worm) hypothetical protein 0.0022 0.0057 0.0097
Plasmodium falciparum glutathione reductase 0.063 0.5689 1
Schistosoma mansoni thyrotropin-releasing hormone receptor 0.0209 0.1793 0.1932
Echinococcus multilocularis glutamate synthase 0.0088 0.0675 0.0669
Echinococcus granulosus lipoxygenase domain containing protein 0.0042 0.0248 0.0242
Toxoplasma gondii NADPH-glutathione reductase 0.0333 0.2939 0.5155
Brugia malayi Tyrosyl-DNA phosphodiesterase family protein 0.0071 0.0511 0.0805
Brugia malayi Dopamine receptor 0.0209 0.1793 0.2822
Trichomonas vaginalis conserved hypothetical protein 0.003 0.0131 0.0446
Brugia malayi Serotonin receptor 0.0701 0.6352 1
Leishmania major phosphopantetheinyl transferase-like protein 0.0025 0.0089 0.0108
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0209 0.1793 0.1932
Echinococcus granulosus FKBP12 rapamycin complex associated protein 0.0048 0.0302 0.0296
Trichomonas vaginalis glucosylceramidase, putative 0.0191 0.1627 0.5535
Echinococcus granulosus cadherin EGF LAG seven pass G type receptor 0.0017 0.0013 0.0007
Plasmodium falciparum dihydrolipoyl dehydrogenase, mitochondrial 0.0333 0.2939 0.5155
Echinococcus granulosus cyclic nucleotide gated cation channel 0.0043 0.0253 0.0247
Echinococcus granulosus short transient receptor potential channel 6 0.0038 0.0208 0.0201
Loa Loa (eye worm) latrophilin receptor protein 2 0.0017 0.0013 0.0022
Echinococcus multilocularis Nuclear hormone receptor family member nhr 41 0.0022 0.0057 0.0051
Echinococcus multilocularis hyperpolarization activated cyclic 0.0043 0.0253 0.0247
Echinococcus multilocularis neuropeptide Y receptor 0.0209 0.1793 0.1787
Onchocerca volvulus 0.0209 0.1793 0.7902
Loa Loa (eye worm) hypothetical protein 0.0201 0.1722 0.2921
Brugia malayi Iron-sulfur cluster assembly accessory protein 0.0052 0.0335 0.0527
Schistosoma mansoni glutamate receptor AMPA 0.0173 0.1462 0.1574
Brugia malayi protein-tyrosine kinase 0.0037 0.0202 0.0318
Echinococcus granulosus potassium voltage gated channel subfamily A 0.0038 0.0205 0.0199
Giardia lamblia Kinase, CMGC MAPK 0.0055 0.0362 0.11
Loa Loa (eye worm) hypothetical protein 0.0209 0.1793 0.304
Leishmania major calmodulin, putative 0.0026 0.01 0.0122
Plasmodium vivax thioredoxin reductase, putative 0.063 0.5689 1
Trichomonas vaginalis PIKK family atypical protein kinase 0.0016 0.0006 0.0022
Giardia lamblia DNA topoisomerase II 0.0142 0.117 0.3891
Mycobacterium ulcerans epimerase 0.0022 0.0057 0.0046
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0313 0.2754 0.9369
Onchocerca volvulus 0.0042 0.0248 0.087
Schistosoma mansoni voltage-gated potassium channel 0.0038 0.0205 0.0215
Echinococcus granulosus sex peptide receptor 0.0209 0.1793 0.1787
Schistosoma mansoni hypothetical protein 0.0438 0.3911 0.4222
Echinococcus granulosus tyrosine protein kinase Src42A 0.0035 0.0183 0.0177
Echinococcus multilocularis NADP dependent isocitrate dehydrogenase 0.0017 0.0014 0.0007
Echinococcus granulosus g protein coupled receptor 0.0209 0.1793 0.1787
Giardia lamblia Glycerol-3-phosphate dehydrogenase 0.0088 0.0675 0.2181
Plasmodium vivax AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.002 0.0043 0.0053
Brugia malayi Steroid receptor seven-up type 2 0.0022 0.0057 0.009
Trypanosoma brucei pyridine nucleotide-disulphide oxidoreductase, putative 0.0088 0.0675 0.0873
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0019 0.0035 0.0118
Echinococcus multilocularis isocitrate dehydrogenase 0.0017 0.0014 0.0007
Toxoplasma gondii ATPase/histidine kinase/DNA gyrase B/HSP90 domain-containing protein 0.0087 0.0665 0.1148
Brugia malayi hypothetical protein 0.0024 0.0083 0.013
Mycobacterium ulcerans fructose-bisphosphate aldolase 0.0153 0.1272 0.4243
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0731 0.6626 0.8642
Echinococcus multilocularis lipoxygenase domain containing protein 0.0042 0.0248 0.0242
Brugia malayi chromobox protein homolog 3 0.0042 0.0244 0.0384
Brugia malayi Voltage-gated potassium channel, Shab-family (KCNB, Kv2-like) alpha-subunit. C. elegans exp-2 ortholog 0.0038 0.0205 0.0322
Plasmodium vivax holo-[acyl-carrier-protein] synthase, putative 0.0025 0.0089 0.0132
Echinococcus multilocularis Basic leucine zipper (bZIP) transcription factor 0.009 0.0689 0.0683
Echinococcus granulosus calmodulin 0.0026 0.01 0.0093
Schistosoma mansoni polycystin 1-related 0.0042 0.0248 0.0261
Treponema pallidum oxidoreductase 0.0088 0.0675 0.2181
Echinococcus multilocularis transient receptor potential cation channel 0.0038 0.0205 0.0199
Brugia malayi cation channel family protein 0.0038 0.0205 0.0322
Mycobacterium ulcerans NADPH:adrenodoxin oxidoreductase FprA 0.0088 0.0675 0.2181
Echinococcus multilocularis voltage gated hydrogen channel 1 0.0038 0.0205 0.0199
Trypanosoma brucei NADPH:adrenodoxin oxidoreductase, mitochondrial, putative 0.0088 0.0675 0.0873
Echinococcus granulosus potassium voltage gated channel protein 0.0038 0.0205 0.0199
Trypanosoma brucei Phosphatidylinositol 3-kinase tor1 0.0048 0.0302 0.0387
Wolbachia endosymbiont of Brugia malayi NADPH-dependent glutamate synthase beta chain 0.0088 0.0675 0.2181
Loa Loa (eye worm) hypothetical protein 0.0652 0.5896 1
Trichomonas vaginalis PIKK family atypical protein kinase 0.0036 0.0188 0.0641
Echinococcus granulosus dihydrolipoamide dehydrogenase 0.0333 0.2939 0.2935
Leishmania major hypothetical protein, conserved 0.0037 0.0197 0.0249
Onchocerca volvulus 0.008 0.0596 0.2457
Echinococcus granulosus DNA apurinic or apyrimidinic site lyase 0.002 0.0043 0.0037
Schistosoma mansoni peptide (FMRFamide/somatostatin)-like receptor 0.0209 0.1793 0.1932
Echinococcus granulosus 7tm_1 domain containing protein 0.0209 0.1793 0.1787
Loa Loa (eye worm) calcium channel 0.0138 0.1133 0.1922
Schistosoma mansoni tyrosine kinase 0.0085 0.0643 0.0688
Echinococcus multilocularis tyrosine protein kinase Fyn 0.0041 0.0239 0.0232
Echinococcus multilocularis L aminoadipate semialdehyde 0.0089 0.0681 0.0675
Loa Loa (eye worm) heterochromatin protein 1 0.0075 0.0548 0.0928
Echinococcus multilocularis tyrosine protein kinase Src64B 0.0041 0.0239 0.0232
Trichomonas vaginalis PIKK family atypical protein kinase 0.0016 0.0006 0.0022
Toxoplasma gondii thioredoxin reductase 0.063 0.5689 1
Leishmania major hypothetical protein, conserved 0.0088 0.0675 0.0873
Echinococcus multilocularis thyrotropin releasing hormone receptor 0.0209 0.1793 0.1787
Trypanosoma brucei calmodulin 0.0026 0.01 0.0122
Trypanosoma cruzi isocitrate dehydrogenase [NADP], mitochondrial precursor, putative 0.0017 0.0014 0.0009
Loa Loa (eye worm) hypothetical protein 0.0019 0.0032 0.0055
Schistosoma mansoni survival motor neuron protein 0.0052 0.0335 0.0355
Loa Loa (eye worm) hypothetical protein 0.0038 0.0205 0.0347
Treponema pallidum DNA gyrase, subunit A (gyrA) 0.0032 0.0155 0.0385
Loa Loa (eye worm) transcription factor SMAD2 0.0128 0.104 0.1764
Echinococcus multilocularis TRP (transient receptor potential) channel 0.0038 0.0205 0.0199
Schistosoma mansoni voltage-gated potassium channel 0.0046 0.0287 0.0303
Trichomonas vaginalis PIKK family atypical protein kinase 0.0038 0.0211 0.0719
Echinococcus granulosus tyrosine protein kinase Src42A 0.0041 0.0239 0.0232
Echinococcus multilocularis glutamate receptor subunit protein glur 0.0074 0.0543 0.0537
Schistosoma mansoni retinoid-x-receptor (RXR) 0.0022 0.0057 0.0055
Trichomonas vaginalis glucosylceramidase, putative 0.0181 0.1537 0.5228
Loa Loa (eye worm) CXXC zinc finger family protein 0.0031 0.0142 0.024
Toxoplasma gondii transporter, cation channel family protein 0.0038 0.0205 0.0337
Schistosoma mansoni hypothetical protein 0.0031 0.0146 0.0151
Brugia malayi Nuclear hormone receptor-like 1 0.0022 0.0057 0.009
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0209 0.1793 0.1787
Leishmania major ferric reductase, putative 0.0036 0.0195 0.0246
Loa Loa (eye worm) phosphatidylinositol 3 0.0016 0.0006 0.001
Schistosoma mansoni thyroid hormone receptor 0.0022 0.0057 0.0055
Echinococcus multilocularis microtubule associated protein 2 0.0738 0.6697 0.6694
Echinococcus granulosus Polycystic kidney disease protein 0.0042 0.0248 0.0242
Echinococcus multilocularis calmodulin 0.0026 0.01 0.0093
Plasmodium falciparum apurinic/apyrimidinic endonuclease Apn1, putative 0.0082 0.0617 0.1063
Echinococcus multilocularis rhodopsin orphan GPCR 0.0209 0.1793 0.1787
Echinococcus granulosus Basic leucine zipper bZIP transcription factor 0.009 0.0689 0.0683
Echinococcus multilocularis 7TM GPCR, rhodopsin 0.0209 0.1793 0.1787
Trypanosoma brucei C-8 sterol isomerase, putative 0.0394 0.3507 0.457
Echinococcus granulosus glutamate receptor NMDA 0.0084 0.0639 0.0633
Trypanosoma cruzi mitogen activated protein kinase 2, putative 0.0055 0.0362 0.0464
Treponema pallidum 4'-phosphopantetheinyl transferase 0.0025 0.0089 0.0157
Schistosoma mansoni voltage-gated potassium channel 0.0038 0.0205 0.0215
Onchocerca volvulus 0.0209 0.1793 0.7902
Loa Loa (eye worm) TK protein kinase 0.0037 0.0202 0.0343
Echinococcus granulosus voltage gated potassium channel 0.0038 0.0205 0.0199
Trypanosoma cruzi cytochrome P450, putative 0.0021 0.0049 0.0056
Loa Loa (eye worm) hypothetical protein 0.0209 0.1793 0.304
Trichomonas vaginalis conserved hypothetical protein 0.0042 0.0244 0.0831
Echinococcus multilocularis Glutamate receptor, ionotropic kainate 2 0.0198 0.1688 0.1682
Trypanosoma cruzi apurinic/apyrimidinic endonuclease 0.002 0.0043 0.0048
Echinococcus granulosus potassium:sodium hyperpolarization activated 0.0043 0.0253 0.0247
Trypanosoma cruzi mitochondrial DNA topoisomerase II, putative 0.0168 0.1412 0.1835
Loa Loa (eye worm) CYP4Cod1 0.0021 0.0049 0.0083
Echinococcus multilocularis thioredoxin glutathione reductase 0.063 0.5689 0.5686
Loa Loa (eye worm) voltage and ligand gated potassium channel 0.0074 0.0547 0.0927
Onchocerca volvulus 0.0209 0.1793 0.7902
Entamoeba histolytica glutamate synthase beta subunit, putative 0.0088 0.0675 0.2331
Mycobacterium tuberculosis Inositol-1-monophosphatase SuhB 0.0035 0.0185 0.0302
Echinococcus multilocularis sodium dependent neurotransmitter transporter 0.0044 0.0264 0.0258
Mycobacterium tuberculosis Dihydrolipoamide dehydrogenase LpdC (lipoamide reductase (NADH)) (lipoyl dehydrogenase) (dihydrolipoyl dehydrogenase) (diaphoras 0.0444 0.3965 0.6963
Schistosoma mansoni calmodulin 0.0026 0.01 0.0101
Echinococcus multilocularis conserved hypothetical protein 0.0738 0.6697 0.6694
Loa Loa (eye worm) hypothetical protein 0.0024 0.0083 0.014
Echinococcus granulosus cpg binding protein 0.0032 0.0158 0.0152
Echinococcus multilocularis 0.0049 0.0315 0.0308
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0313 0.2754 0.9369
Echinococcus multilocularis growth hormone secretagogue receptor type 1 0.0209 0.1793 0.1787
Echinococcus multilocularis G-protein coupled receptor, putative 0.0209 0.1793 0.1787
Echinococcus granulosus neuropeptide Y receptor 0.0209 0.1793 0.1787
Brugia malayi isocitrate dehydrogenase 0.0017 0.0014 0.0021
Onchocerca volvulus Steroid hormone receptor family member cnr14 homolog 0.0022 0.0057 0.0003
Echinococcus multilocularis tyrosyl DNA phosphodiesterase 1 0.0071 0.0511 0.0505
Leishmania major 2,4-dienoyl-coa reductase fadh1, putative 0.0088 0.0675 0.0873
Loa Loa (eye worm) TK/INSR protein kinase 0.0052 0.034 0.0576
Onchocerca volvulus 0.0029 0.0124 0.0307
Toxoplasma gondii transporter, cation channel family protein 0.0038 0.0205 0.0337
Echinococcus multilocularis voltage dependent calcium channel 0.0138 0.1133 0.1128
Trichomonas vaginalis voltage and ligand gated potassium channel, putative 0.0043 0.0253 0.0862
Trichomonas vaginalis disulfide oxidoreductase, putative 0.0088 0.0675 0.2297
Onchocerca volvulus 0.0045 0.0272 0.098
Loa Loa (eye worm) hypothetical protein 0.0022 0.0057 0.0097
Onchocerca volvulus 0.0209 0.1793 0.7902
Schistosoma mansoni thyroid hormone receptor 0.0022 0.0057 0.0055
Plasmodium falciparum ataxin-2 like protein, putative 0.0027 0.0107 0.0164
Echinococcus granulosus sodium leak channel non selective protein 0.0038 0.0205 0.0199
Schistosoma mansoni tyrosine kinase 0.0026 0.0102 0.0103
Echinococcus granulosus tyrosine protein kinase Fyn 0.0041 0.0239 0.0232
Echinococcus multilocularis chromobox protein 1 0.0075 0.0548 0.0541
Onchocerca volvulus 0.0088 0.0675 0.2815
Trypanosoma brucei hypothetical protein, conserved 0.0088 0.0675 0.0873
Schistosoma mansoni voltage-gated potassium channel 0.0038 0.0205 0.0215
Loa Loa (eye worm) hypothetical protein 0.0044 0.0264 0.0447
Plasmodium vivax calmodulin, putative 0.0026 0.01 0.0152
Schistosoma mansoni sulfide quinone reductase 0.0088 0.0675 0.0723
Brugia malayi steroid hormone receptor 0.0022 0.0057 0.009
Echinococcus multilocularis mitogen activated protein kinase 0.0055 0.0362 0.0356
Loa Loa (eye worm) hypothetical protein 0.0209 0.1793 0.304
Trichomonas vaginalis disulfide oxidoreductase, putative 0.0088 0.0675 0.2297
Trichomonas vaginalis dihydropyrimidine dehydrogenase, putative 0.0088 0.0675 0.2297
Brugia malayi Guanylyl cyclase protein 23 0.003 0.0135 0.0212
Echinococcus granulosus pyroglutamylated rfamide peptide receptor 0.0209 0.1793 0.1787
Echinococcus multilocularis tyrosine protein kinase lyn lyn a protein tyrosine kinase lymphocyte specific protein tyrosine kinase 0.0041 0.0239 0.0232
Echinococcus granulosus dro:myosuppressin receptor 0.0209 0.1793 0.1787
Schistosoma mansoni DNA topoisomerase II 0.015 0.1242 0.1337
Schistosoma mansoni calcium-activated potassium channel 0.0038 0.0205 0.0215
Loa Loa (eye worm) intermediate filament protein 0.0029 0.0124 0.021
Schistosoma mansoni jumonji/arid domain-containing protein 0.004 0.0223 0.0234
Echinococcus multilocularis ryanodine receptor 44f 0.0038 0.0205 0.0199
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0209 0.1793 0.1932
Onchocerca volvulus Protein ultraspiracle homolog 0.0022 0.0057 0.0003
Brugia malayi jmjC domain containing protein 0.004 0.0223 0.0351
Mycobacterium tuberculosis DNA gyrase (subunit A) GyrA (DNA topoisomerase (ATP-hydrolysing)) (DNA topoisomerase II) (type II DNA topoisomerase) 0.0032 0.0155 0.0249
Schistosoma mansoni hypothetical protein 0.0181 0.1537 0.1655
Plasmodium vivax ataxin-2 like protein, putative 0.0027 0.0107 0.0164
Echinococcus granulosus mitogen activated protein kinase 0.0055 0.0362 0.0356
Loa Loa (eye worm) G-protein coupled receptor 0.0209 0.1793 0.304
Leishmania major target of rapamycin (TOR) kinase 2, putative 0.0048 0.0302 0.0387
Onchocerca volvulus 0.0044 0.0264 0.0942
Echinococcus multilocularis orexin receptor type 2 0.0209 0.1793 0.1787
Mycobacterium ulcerans carbon monoxyde dehydrogenase large chain CoxL 0.0087 0.0667 0.2152
Schistosoma mansoni sodium/chloride dependent transporter 0.0259 0.2254 0.243
Mycobacterium tuberculosis Probable carbon monoxyde dehydrogenase (medium chain) 0.0063 0.0437 0.0746
Onchocerca volvulus Calmodulin homolog 0.0026 0.01 0.0195
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0019 0.0035 0.0118
Mycobacterium tuberculosis Probable NADH dehydrogenase Ndh 0.0199 0.1701 0.2973
Toxoplasma gondii 4'-phosphopantetheinyl transferase domain-containing protein 0.0025 0.0089 0.0132
Loa Loa (eye worm) hypothetical protein 0.0041 0.0239 0.0405
Toxoplasma gondii pyridine nucleotide-disulfide oxidoreductase domain-containing protein 0.0088 0.0675 0.1166
Entamoeba histolytica dihydropyrimidine dehydrogenase, putative 0.0088 0.0675 0.2331
Mycobacterium ulcerans hypothetical protein 0.0022 0.0057 0.0046
Brugia malayi Unidentified vitellogenin-linked transcript protein 6, putative 0.0209 0.1793 0.2822
Trypanosoma brucei calmodulin 0.0026 0.01 0.0122
Trypanosoma cruzi tyrosyl-DNA Phosphodiesterase (Tdp1), putative 0.0071 0.0511 0.0659
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0033 0.0159 0.0165
Loa Loa (eye worm) hypothetical protein 0.0209 0.1793 0.304
Echinococcus granulosus pyridine nucleotide disulfide oxidoreductase 0.0088 0.0675 0.0669
Echinococcus granulosus neuropeptide receptor A26 0.0701 0.6352 0.635
Leishmania major target of rapamycin (TOR) kinase 1, putative 0.0048 0.0302 0.0387
Toxoplasma gondii Erv1 / Alr family protein 0.0037 0.0197 0.0323
Schistosoma mansoni jun-related protein 0.0073 0.0533 0.057
Brugia malayi Glutamate receptor 1 precursor 0.0173 0.1462 0.2301
Trichomonas vaginalis glucosylceramidase, putative 0.0276 0.2417 0.8222
Echinococcus granulosus COUP TF:Svp nuclear hormone receptor 0.0022 0.0057 0.0051
Echinococcus granulosus adenylate cyclase 9 0.0083 0.0629 0.0623
Schistosoma mansoni opsin-like receptor 0.0209 0.1793 0.1932
Trypanosoma brucei phosphatidylinositol 3-kinase tor, putative 0.0023 0.0068 0.008
Loa Loa (eye worm) hypothetical protein 0.0024 0.0083 0.014
Echinococcus multilocularis inositol monophosphatase 1 0.004 0.0223 0.0217
Toxoplasma gondii NADH dehydrogenase (NDH2-II) 0.0088 0.0675 0.1166
Echinococcus granulosus hepatocyte nuclear factor 4 alpha 0.0022 0.0057 0.0051
Echinococcus granulosus mitogen activated protein kinase 3 0.0055 0.0362 0.0356
Loa Loa (eye worm) hypothetical protein 0.0043 0.0253 0.0429
Echinococcus multilocularis hyperpolarization activated cyclic 0.0043 0.0253 0.0247
Echinococcus multilocularis rhodopsin orphan GPCR 0.0209 0.1793 0.1787
Loa Loa (eye worm) jmjC domain-containing protein 0.0064 0.0454 0.0769
Echinococcus multilocularis potassium voltage gated channel subfamily D 0.0038 0.0205 0.0199
Brugia malayi neuropeptide F receptor 0.0209 0.1793 0.2822
Schistosoma mansoni transient receptor potential channel 0.0038 0.0205 0.0215
Loa Loa (eye worm) hypothetical protein 0.0209 0.1793 0.304
Trypanosoma cruzi calmodulin 0.0026 0.01 0.0122
Entamoeba histolytica DNA topoisomerase II, putative 0.015 0.1242 0.4424
Brugia malayi Nuclear hormone receptor family member nhr-41 0.0022 0.0057 0.009
Onchocerca volvulus Heterochromatin protein 1 homolog 0.0045 0.0274 0.0986
Echinococcus granulosus retinoic acid receptor rxr beta a 0.0022 0.0057 0.0051
Brugia malayi Voltage-gated potassium channel, Shaw-family (KCNC, Kv3-like) alpha-subunit 0.0038 0.0205 0.0322
Echinococcus granulosus tachykinin peptides receptor 99D 0.0209 0.1793 0.1787
Brugia malayi hypothetical protein 0.0044 0.0264 0.0415
Trichomonas vaginalis glucosylceramidase, putative 0.0181 0.1537 0.5228
Trypanosoma brucei calmodulin 0.0026 0.01 0.0122
Echinococcus granulosus tm gpcr rhodopsin 0.0209 0.1793 0.1787
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0022 0.0057 0.0051
Echinococcus granulosus calmodulin 0.0026 0.01 0.0093
Plasmodium falciparum glutathione reductase 0.0333 0.2939 0.5155
Loa Loa (eye worm) pigment dispersing factor receptor c 0.0053 0.0351 0.0595
Onchocerca volvulus 0.0209 0.1793 0.7902
Loa Loa (eye worm) hypothetical protein 0.0038 0.0205 0.0347
Brugia malayi G protein-coupled receptor F59B2.13 0.0209 0.1793 0.2822
Echinococcus granulosus biogenic amine 5HT receptor 0.1015 0.9254 0.9253
Echinococcus granulosus voltage dependent calcium channel type d subunit|voltage dependent calcium channel alpha 1 0.0138 0.1133 0.1128
Mycobacterium tuberculosis Probable exodeoxyribonuclease III protein XthA (exonuclease III) (EXO III) (AP endonuclease VI) 0.002 0.0043 0.0053
Loa Loa (eye worm) programmed cell death 8 0.0088 0.0675 0.1145
Echinococcus granulosus peregrin 0.0031 0.0146 0.014
Loa Loa (eye worm) TK/EGFR protein kinase 0.0161 0.1346 0.2282
Trypanosoma cruzi 2,4-dienoyl-coa reductase fadh1, putative 0.0088 0.0675 0.0873
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0209 0.1793 0.1932
Onchocerca volvulus 0.0209 0.1793 0.7902
Echinococcus multilocularis lamin dm0 0.0029 0.0124 0.0118
Trichomonas vaginalis PIKK family atypical protein kinase 0.0038 0.0211 0.0719
Toxoplasma gondii 4'-phosphopantetheinyl transferase superfamily protein 0.0025 0.0089 0.0132
Echinococcus multilocularis jun protein 0.009 0.0689 0.0683
Trypanosoma brucei Voltage-dependent calcium channel subunit, putative 0.0098 0.076 0.0984
Echinococcus multilocularis rhodopsin orphan GPCR 0.0209 0.1793 0.1787
Echinococcus multilocularis voltage dependent calcium channel type d subunit 0.0138 0.1133 0.1128
Brugia malayi ion channel NompC 0.0038 0.0205 0.0322
Echinococcus multilocularis allatostatin A receptor 0.0209 0.1793 0.1787
Loa Loa (eye worm) hypothetical protein 0.0024 0.0083 0.014
Loa Loa (eye worm) hypothetical protein 0.0019 0.0032 0.0055
Loa Loa (eye worm) voltage-dependent calcium channel 0.0057 0.038 0.0645
Echinococcus granulosus metabotropic glutamate receptor 5 0.0024 0.0083 0.0077
Trichomonas vaginalis xanthine dehydrogenase, putative 0.0185 0.1574 0.5357
Schistosoma mansoni nuclear receptor 2DBD-gamma 0.0022 0.0057 0.0055
Leishmania major 2,4-dienoyl-coa reductase-like protein 0.0088 0.0675 0.0873
Trichomonas vaginalis glucosylceramidase, putative 0.0276 0.2417 0.8222
Mycobacterium tuberculosis holo-[acyl-carrier protein] synthase AcpS (holo-ACP synthase) (CoA:APO-[ACP]pantetheinephosphotransferase) (CoA:APO-[acyl-carrie 0.0025 0.0089 0.0132
Schistosoma mansoni Tr4/Tr2 (homologue) 0.0022 0.0057 0.0055
Schistosoma mansoni voltage-gated potassium channel 0.0078 0.058 0.062
Entamoeba histolytica protein kinase, putative 0.0033 0.0165 0.0448
Mycobacterium ulcerans aerobic-type carbon monoxide dehydrogenase subunit CoxM_2 0.0063 0.0437 0.1359
Echinococcus multilocularis cpg binding protein 0.0032 0.0158 0.0152
Onchocerca volvulus 0.0042 0.0248 0.087
Trichomonas vaginalis glutamate synthase, putative 0.0088 0.0675 0.2297
Plasmodium vivax SET domain protein, putative 0.0033 0.0159 0.0256
Trypanosoma cruzi Present in the outer mitochondrial membrane proteome 4 0.0037 0.0197 0.0249
Schistosoma mansoni voltage-gated potassium channel 0.0038 0.0205 0.0215
Schistosoma mansoni transient receptor potential channel 4 0.0038 0.0205 0.0215
Toxoplasma gondii hypothetical protein 0.0044 0.0264 0.0441
Schistosoma mansoni transient receptor potential cation channel subfamily m member 0.0038 0.0205 0.0215
Onchocerca volvulus Transient receptor potential cation channel trpm homolog 0.0038 0.0205 0.0675
Echinococcus granulosus tyrosine kinase 0.0026 0.0102 0.0095
Echinococcus granulosus diuretic hormone 44 receptor GPRdih2 0.0017 0.0013 0.0007
Schistosoma mansoni voltage-gated potassium channel 0.0038 0.0205 0.0215
Mycobacterium ulcerans DNA gyrase subunit A 0.0032 0.0155 0.0385
Trichomonas vaginalis glucosylceramidase, putative 0.0276 0.2417 0.8222
Echinococcus granulosus ecdysone induced protein 78C 0.0022 0.0057 0.0051
Loa Loa (eye worm) cyclic-nucleotide gated cation channel 0.0043 0.0253 0.0429
Brugia malayi Nuclear hormone receptor family member nhr-3 0.0022 0.0057 0.009
Onchocerca volvulus 0.0031 0.0142 0.0386
Schistosoma mansoni norepinephrine/norepinephrine transporter 0.0259 0.2254 0.243
Echinococcus granulosus allatostatin A receptor 0.0209 0.1793 0.1787
Echinococcus multilocularis g protein linked acetylcholine receptor gar 2a 0.0209 0.1793 0.1787
Loa Loa (eye worm) hypothetical protein 0.0044 0.0264 0.0447
Brugia malayi G-protein coupled receptor 0.0209 0.1793 0.2822
Schistosoma mansoni ancient conserved domain protein 2 (cyclin m2) 0.0209 0.1793 0.1932
Trypanosoma brucei tyrosyl-DNA Phosphodiesterase (Tdp1), putative 0.0071 0.0511 0.0659
Mycobacterium ulcerans 4'-phosphopantetheinyl transferase 0.0025 0.0089 0.0157
Echinococcus multilocularis g protein linked acetylcholine receptor gar 2a 0.0209 0.1793 0.1787
Echinococcus granulosus thyrotropin releasing hormone receptor 0.0209 0.1793 0.1787
Loa Loa (eye worm) hypothetical protein 0.0209 0.1793 0.304
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0019 0.0033 0.0029
Echinococcus granulosus 3'partial|tyrosine protein kinase Fgr 0.0041 0.0239 0.0232
Trypanosoma brucei pyridine nucleotide-disulphide oxidoreductase, putative 0.0088 0.0675 0.0873
Loa Loa (eye worm) hypothetical protein 0.0209 0.1793 0.304
Schistosoma mansoni tyrosine kinase 0.0087 0.0662 0.0709
Mycobacterium ulcerans flavoprotein disulfide reductase 0.0333 0.2939 1
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0022 0.0057 0.009
Schistosoma mansoni sodium/chloride dependent transporter 0.0044 0.0264 0.0278
Toxoplasma gondii hypothetical protein 0.0038 0.0205 0.0337
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.1095 1 1
Echinococcus multilocularis transient receptor potential cation channel 0.0038 0.0205 0.0199
Brugia malayi exodeoxyribonuclease III family protein 0.002 0.0043 0.0068
Loa Loa (eye worm) hypothetical protein 0.0053 0.0347 0.0589
Trypanosoma cruzi hypothetical protein, conserved 0.0088 0.0675 0.0873
Schistosoma mansoni ap endonuclease 0.002 0.0043 0.004
Schistosoma mansoni voltage-gated potassium channel 0.0038 0.0205 0.0215
Brugia malayi hypothetical protein 0.0209 0.1793 0.2822
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0066 0.0472 0.0503
Echinococcus granulosus tyrosine protein kinase Fyn 0.0041 0.0239 0.0232
Schistosoma mansoni hypothetical protein 0.0074 0.0543 0.058
Echinococcus granulosus somatostatin receptor 0.0209 0.1793 0.1787
Loa Loa (eye worm) hypothetical protein 0.0057 0.038 0.0645
Trichomonas vaginalis voltage and ligand gated potassium channel, putative 0.0049 0.0313 0.1064
Echinococcus granulosus potassium voltage gated channel protein 0.0038 0.0205 0.0199
Echinococcus granulosus g protein coupled receptor 0.0209 0.1793 0.1787
Plasmodium vivax ferrodoxin reductase, putative 0.0088 0.0675 0.1166
Schistosoma mansoni tyrosine kinase 0.0087 0.0662 0.0709
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0022 0.0057 0.009
Onchocerca volvulus 0.0209 0.1793 0.7902
Onchocerca volvulus 0.0209 0.1793 0.7902
Echinococcus granulosus glutamate receptor ionotrophic AMPA 3 0.0198 0.1688 0.1682
Mycobacterium ulcerans cytochrome P450 185A4 Cyp185A4 0.0021 0.0049 0.002
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0019 0.0035 0.0118
Mycobacterium tuberculosis Probable NADPH dependent 2,4-dienoyl-CoA reductase FadH (2,4-dienoyl coenzyme A reductase) (4-enoyl-CoA reductase) 0.0088 0.0675 0.1166
Schistosoma mansoni cyclic-nucleotide-gated cation channel 0.0043 0.0253 0.0267
Echinococcus granulosus transient receptor potential cation channel 0.0038 0.0205 0.0199
Echinococcus multilocularis DNA topoisomerase 2 alpha 0.015 0.1242 0.1237
Mycobacterium ulcerans glutamate synthase subunit beta 0.0088 0.0675 0.2181
Plasmodium vivax FAD-linked sulfhydryl oxidase ERV1, putative 0.0037 0.0197 0.0323
Schistosoma mansoni voltage-gated potassium channel 0.0043 0.0253 0.0267
Entamoeba histolytica myo-inositol monophosphatase, putative 0.004 0.0223 0.0663
Trichomonas vaginalis glutamate synthase, putative 0.0088 0.0675 0.2297
Echinococcus multilocularis cyclic nucleotide gated cation channel 0.0043 0.0253 0.0247
Mycobacterium ulcerans carbon monoxyde dehydrogenase small chain CoxS 0.0035 0.0185 0.0489
Brugia malayi jmjC domain containing protein 0.0102 0.0803 0.1264
Echinococcus granulosus rhodopsin orphan GPCR 0.0209 0.1793 0.1787
Echinococcus multilocularis potassium voltage gated channel protein 0.0038 0.0205 0.0199
Echinococcus multilocularis lipoxygenase domain containing protein 0.0042 0.0248 0.0242
Trichomonas vaginalis PIKK family atypical protein kinase 0.0029 0.0123 0.0419
Echinococcus multilocularis arachidonate 5 lipoxygenase 0.0185 0.1573 0.1568
Brugia malayi hypothetical protein 0.0209 0.1793 0.2822
Onchocerca volvulus 0.0038 0.0205 0.0675
Loa Loa (eye worm) hypothetical protein 0.0038 0.0205 0.0347
Brugia malayi MH2 domain containing protein 0.0128 0.104 0.1637
Schistosoma mansoni neuropeptide receptor 0.0209 0.1793 0.1932
Onchocerca volvulus 0.0209 0.1793 0.7902
Brugia malayi Voltage-gated potassium channel, Shaw-family (KCNC, Kv3-like) alpha-subunit. C. elegans egl-36 ortholog 0.0038 0.0205 0.0322
Brugia malayi putative neuropeptide receptor NPR1 0.0209 0.1793 0.2822
Schistosoma mansoni opsin-like receptor 0.0209 0.1793 0.1932
Echinococcus multilocularis tyrosine protein kinase Srms 0.0037 0.0202 0.0196
Echinococcus multilocularis tumor protein p63 0.0362 0.3206 0.3202
Giardia lamblia Thioredoxin reductase 0.0088 0.0675 0.2181
Onchocerca volvulus DNA topoisomerase 2 homolog 0.0101 0.0793 0.3352
Echinococcus granulosus hypothetical protein 0.0947 0.8632 0.8631
Schistosoma mansoni ap endonuclease 0.002 0.0043 0.004
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0022 0.0057 0.0051
Trypanosoma brucei calmodulin 0.0026 0.01 0.0122
Loa Loa (eye worm) hypothetical protein 0.0069 0.0498 0.0845
Trypanosoma cruzi trypanothione reductase, putative 0.0333 0.2939 0.3829
Loa Loa (eye worm) hypothetical protein 0.0209 0.1793 0.304
Mycobacterium ulcerans NADH dehydrogenase 0.0088 0.0675 0.2181
Echinococcus multilocularis tyrosine protein kinase lyn tyrosine protein kinase blk 0.0041 0.0239 0.0232
Mycobacterium ulcerans hypothetical protein 0.0088 0.0675 0.2181
Brugia malayi G-protein-linked acetylcholine receptor protein 2, putative 0.0209 0.1793 0.2822
Leishmania major hypothetical protein, conserved 0.0088 0.0675 0.0873
Trypanosoma brucei DNA topoisomerase II alpha, putative 0.0141 0.1168 0.1516
Loa Loa (eye worm) hypothetical protein 0.0044 0.0264 0.0447
Plasmodium vivax hypothetical protein, conserved 0.0031 0.0146 0.0233
Echinococcus granulosus potassium voltage gated channel subfamily C 0.0038 0.0205 0.0199
Echinococcus granulosus nmda type glutamate receptor 0.0199 0.1699 0.1694
Brugia malayi Furin-like cysteine rich region family protein 0.0161 0.1346 0.2118
Mycobacterium leprae conserved hypothetical protein 0.0025 0.0089 0.0082
Loa Loa (eye worm) hypothetical protein 0.0209 0.1793 0.304
Toxoplasma gondii pyridine nucleotide-disulfide oxidoreductase domain-containing protein 0.0088 0.0675 0.1166
Trichomonas vaginalis PIKK family atypical protein kinase 0.0026 0.0097 0.0331
Chlamydia trachomatis endonuclease IV 0.0082 0.0617 0.1852
Loa Loa (eye worm) hypothetical protein 0.0209 0.1793 0.304
Brugia malayi Voltage-gated potassium channel, HERG (KCNH2)-related. C. elegans unc-103 ortholog 0.0074 0.0547 0.086
Schistosoma mansoni calcium channel voltage-dependent p/q type alpha 1a-related 0.0038 0.0205 0.0215
Brugia malayi gonadotropin-releasing hormone receptor 2 0.0209 0.1793 0.2822
Wolbachia endosymbiont of Brugia malayi DNA gyrase subunit A 0.0032 0.0155 0.0385
Schistosoma mansoni tyrosine kinase 0.0052 0.034 0.0361
Loa Loa (eye worm) MH2 domain-containing protein 0.0128 0.104 0.1764
Brugia malayi nuclear receptor NHR-88 0.0022 0.0057 0.009
Echinococcus granulosus neuropeptides capa receptor 0.0209 0.1793 0.1787
Mycobacterium tuberculosis Probable thioredoxin reductase TrxB2 (TRXR) (TR) 0.0088 0.0675 0.1166
Trypanosoma brucei dihydrolipoamide dehydrogenase 0.0731 0.6626 0.8642
Schistosoma mansoni biogenic amine (5HT) receptor 0.047 0.4207 0.4542
Echinococcus granulosus thioredoxin glutathione reductase 0.063 0.5689 0.5686
Echinococcus granulosus melanoma receptor tyrosine protein kinase 0.0087 0.0662 0.0656
Echinococcus multilocularis histone lysine methyltransferase setb histone lysine methyltransferase eggless 0.0033 0.0159 0.0153
Brugia malayi Tachykinin-like peptides receptor 99D 0.0209 0.1793 0.2822
Mycobacterium ulcerans carbon monoxyde dehydrogenase medium chain CoxM 0.0063 0.0437 0.1359
Echinococcus granulosus NADPH:adrenodoxin oxidoreductase 0.0088 0.0675 0.0669
Echinococcus multilocularis calmodulin 0.0026 0.01 0.0093
Mycobacterium ulcerans phosphopantetheinyl transferase, PptII 0.0025 0.0089 0.0157
Mycobacterium tuberculosis Conserved hypothetical protein 0.0022 0.0057 0.0076
Loa Loa (eye worm) hypothetical protein 0.0021 0.0047 0.008
Brugia malayi Ryanodine Receptor TM 4-6 family protein 0.0038 0.0205 0.0323
Entamoeba histolytica calmodulin, putative 0.0026 0.01 0.0208
Echinococcus granulosus neuropeptide FF receptor 2 0.0209 0.1793 0.1787
Mycobacterium tuberculosis NAD(P)H quinone reductase LpdA 0.0444 0.3965 0.6963
Trichomonas vaginalis PIKK family atypical protein kinase 0.0048 0.0302 0.1029
Toxoplasma gondii exonuclease III APE 0.002 0.0043 0.0053
Trypanosoma brucei dihydrolipoamide dehydrogenase 0.0843 0.7666 1
Loa Loa (eye worm) nuclear hormone receptor family member nhr-40 0.0022 0.0057 0.0097
Onchocerca volvulus 0.0044 0.0264 0.0942
Loa Loa (eye worm) hypothetical protein 0.0209 0.1793 0.304
Brugia malayi sulfakinin receptor protein 0.0209 0.1793 0.2822
Treponema pallidum hypothetical protein 0.0025 0.0087 0.015
Onchocerca volvulus 0.0071 0.0511 0.2066
Echinococcus granulosus FAD linked sulfhydryl oxidase ALR 0.0037 0.0197 0.0191
Trypanosoma cruzi Phosphatidylinositol 3-kinase tor1 0.0048 0.0302 0.0387
Echinococcus multilocularis tyrosine protein kinase Fyn 0.0041 0.0239 0.0232
Echinococcus multilocularis voltage gated potassium channel 0.0046 0.0287 0.0281
Brugia malayi Heterochromatin protein 1 0.0075 0.0548 0.0862
Brugia malayi Metabotropic glutamate receptor precursor. 0.0024 0.0083 0.013
Echinococcus multilocularis Polycystic kidney disease protein 0.0042 0.0248 0.0242
Loa Loa (eye worm) hypothetical protein 0.0022 0.0057 0.0097
Echinococcus granulosus GPCR family 2 0.0017 0.0013 0.0007
Brugia malayi Augmenter of liver regeneration 0.0037 0.0197 0.031
Echinococcus granulosus potassium voltage gated channel protein 0.0038 0.0205 0.0199
Schistosoma mansoni lipoxygenase 0.0185 0.1573 0.1694
Trichomonas vaginalis set domain proteins, putative 0.0254 0.2211 0.7522
Trichomonas vaginalis PIKK family atypical protein kinase 0.0036 0.0188 0.0641
Onchocerca volvulus 0.0029 0.0124 0.0307
Echinococcus granulosus uncharacterized sodium dependent transporter 0.0044 0.0264 0.0258
Loa Loa (eye worm) hypothetical protein 0.0209 0.1793 0.304
Echinococcus multilocularis cadherin EGF LAG seven pass G type receptor 0.0017 0.0013 0.0007
Echinococcus granulosus alpha 1A adrenergic receptor 0.0209 0.1793 0.1787
Schistosoma mansoni sodium/chloride dependent neurotransmitter transporter 0.0044 0.0264 0.0278
Mycobacterium ulcerans NADPH:adrenodoxin oxidoreductase FprA 0.0088 0.0675 0.2181
Mycobacterium leprae Probable fructose bisphosphate aldolase Fba 0.0153 0.1272 0.311
Loa Loa (eye worm) solute carrier family 6 member 4 0.0259 0.2254 0.3822
Onchocerca volvulus Neuropeptide F receptor homolog 0.0209 0.1793 0.7902
Leishmania major myo-inositol-1(or 4)-monophosphatase 1, putative 0.004 0.0223 0.0283
Schistosoma mansoni aminoadipate-semialdehyde dehydrogenase 0.0089 0.0681 0.073
Echinococcus multilocularis transient receptor potential gamma protein 0.0038 0.0205 0.0199
Entamoeba histolytica disulphide oxidoreductase, putative 0.0088 0.0675 0.2331
Echinococcus multilocularis pyroglutamylated rfamide peptide receptor 0.0209 0.1793 0.1787
Brugia malayi voltage-dependent calcium channel 0.0038 0.0205 0.0322
Brugia malayi Receptor family ligand binding region containing protein 0.003 0.0135 0.0212
Mycobacterium ulcerans thioredoxin reductase TrxB2 0.0088 0.0675 0.2181
Echinococcus multilocularis nmda type glutamate receptor 0.0109 0.0865 0.0859
Mycobacterium tuberculosis Probable dehydrogenase 0.0199 0.1701 0.2973
Echinococcus granulosus jun protein 0.009 0.0689 0.0683
Echinococcus multilocularis potassium voltage gated channel protein 0.0038 0.0205 0.0199
Brugia malayi DNA gyrase/topoisomerase IV, A subunit family protein 0.015 0.1242 0.1956
Echinococcus granulosus nmda type glutamate receptor 0.0109 0.0865 0.0859
Mycobacterium ulcerans sugar phosphate isomerases/epimerases 0.0022 0.0057 0.0046
Schistosoma mansoni adenoreceptor 0.0209 0.1793 0.1932
Trypanosoma cruzi apurinic/apyrimidinic endonuclease, putative 0.002 0.0043 0.0048
Trichomonas vaginalis PIKK family atypical protein kinase 0.0038 0.0211 0.0719
Onchocerca volvulus 0.0022 0.0057 0.0003
Loa Loa (eye worm) hypothetical protein 0.0209 0.1793 0.304
Loa Loa (eye worm) hypothetical protein 0.0652 0.5896 1
Echinococcus granulosus tyrosine protein kinase Src64B 0.0041 0.0239 0.0232
Mycobacterium ulcerans NADPH:adrenodoxin oxidoreductase FprB 0.0088 0.0675 0.2181
Echinococcus multilocularis Transcription factor, JmjC domain containing protein 0.0102 0.0803 0.0798
Brugia malayi hypothetical protein 0.0209 0.1793 0.2822
Echinococcus granulosus microtubule associated protein 2 0.0738 0.6697 0.6694
Echinococcus multilocularis RUN 0.0042 0.0248 0.0242
Schistosoma mansoni biogenic amine receptor 0.0209 0.1793 0.1932
Trypanosoma cruzi cytochrome P450, putative 0.0021 0.0049 0.0056
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0843 0.7666 1
Echinococcus multilocularis isocitrate dehydrogenase 2 (NADP+) 0.0017 0.0014 0.0007
Loa Loa (eye worm) hypothetical protein 0.0038 0.0205 0.0347
Schistosoma mansoni transient receptor potential cation channel subfamily m member 0.0038 0.0205 0.0215
Echinococcus multilocularis calmodulin 0.0026 0.01 0.0093
Toxoplasma gondii calmodulin, putative 0.0026 0.01 0.0152
Loa Loa (eye worm) Sodium:neurotransmitter symporter family protein 0.0044 0.0264 0.0447
Toxoplasma gondii LsmAD domain-containing protein 0.0027 0.0107 0.0164
Loa Loa (eye worm) hypothetical protein 0.0031 0.0146 0.0247
Trichomonas vaginalis conserved hypothetical protein 0.0042 0.0244 0.0831
Brugia malayi Bromodomain containing protein 0.0031 0.0146 0.0229
Mycobacterium ulcerans extragenic suppressor protein SuhB 0.004 0.0223 0.062
Echinococcus multilocularis potassium voltage gated channel subfamily D 0.0038 0.0205 0.0199
Trichomonas vaginalis PIKK family atypical protein kinase 0.0026 0.0098 0.0332
Echinococcus granulosus PHD finger protein rhinoceros 0.0031 0.0146 0.014
Mycobacterium tuberculosis Probable NADPH:adrenodoxin oxidoreductase FprB (adrenodoxin reductase) (AR) (ferredoxin-NADP(+) reductase) 0.0088 0.0675 0.1166
Trichomonas vaginalis chromobox protein, putative 0.0045 0.0274 0.0931
Toxoplasma gondii PHD-finger domain-containing protein 0.0031 0.0146 0.0233
Brugia malayi hypothetical protein 0.0071 0.0511 0.0803
Trichomonas vaginalis mercuric reductase, putative 0.0333 0.2939 1
Loa Loa (eye worm) TK protein kinase 0.0033 0.0165 0.0279
Echinococcus multilocularis potassium voltage gated channel protein 0.0038 0.0205 0.0199
Schistosoma mansoni amine GPCR 0.0741 0.6717 0.7257
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.0038 0.0205 0.0337
Giardia lamblia NADH oxidase lateral transfer candidate 0.0333 0.2939 1
Echinococcus granulosus rhodopsin orphan GPCR 0.0209 0.1793 0.1787
Trichomonas vaginalis PIKK family atypical protein kinase 0.0036 0.0188 0.0641
Brugia malayi hypothetical protein 0.0027 0.0107 0.0168
Schistosoma mansoni lipoxygenase 0.0109 0.087 0.0933
Echinococcus multilocularis g protein coupled receptor 0.0209 0.1793 0.1787
Trypanosoma cruzi isocitrate dehydrogenase, putative 0.0017 0.0014 0.0009
Mycobacterium ulcerans carbon monoxyde dehydrogenase small chain CoxS 0.0035 0.0185 0.0489
Schistosoma mansoni glutamate receptor kainate 0.0173 0.1462 0.1574
Loa Loa (eye worm) hypothetical protein 0.0209 0.1793 0.304
Loa Loa (eye worm) hypothetical protein 0.0083 0.0629 0.1067
Brugia malayi Pyridine nucleotide-disulphide oxidoreductase family protein 0.0088 0.0675 0.1063
Brugia malayi glutamate synthase 0.0088 0.0675 0.1063
Echinococcus granulosus tm gpcr rhodopsin 0.0763 0.6922 0.692
Schistosoma mansoni voltage-gated potassium channel 0.0038 0.0205 0.0215
Echinococcus multilocularis dro:myosuppressin receptor 0.0209 0.1793 0.1787
Echinococcus granulosus tyrosine protein kinase Blk 0.0037 0.0202 0.0196
Echinococcus granulosus shaker cognate 0.0038 0.0205 0.0199
Brugia malayi Cytochrome P450 family protein 0.0021 0.0049 0.0077
Schistosoma mansoni hypothetical protein 0.0073 0.0533 0.057
Entamoeba histolytica fructose-1,6-bisphosphate aldolase, putative 0.0313 0.2754 1
Brugia malayi Cyclic-nucleotide gated cation channel 0.0043 0.0253 0.0398
Plasmodium falciparum calmodulin 0.0026 0.01 0.0152
Schistosoma mansoni protein kinase 0.003 0.0135 0.0139
Leishmania major calmodulin, putative 0.0026 0.01 0.0122
Schistosoma mansoni histone-lysine n-methyltransferase suv9 0.0045 0.0272 0.0287
Trypanosoma brucei ferric reductase transmembrane protein, putative 0.0036 0.0195 0.0246
Schistosoma mansoni tyrosine kinase 0.0085 0.0643 0.0688
Onchocerca volvulus 0.0209 0.1793 0.7902
Mycobacterium tuberculosis Probable membrane NADH dehydrogenase NdhA 0.0199 0.1701 0.2973
Loa Loa (eye worm) hypothetical protein 0.0209 0.1793 0.304
Leishmania major acetoin dehydrogenase e3 component-like protein 0.0656 0.593 0.7734
Brugia malayi Sodium:neurotransmitter symporter family protein 1, putative 0.0044 0.0264 0.0415
Mycobacterium tuberculosis Probable nitrite reductase [NAD(P)H] large subunit [FAD flavoprotein] NirB 0.0199 0.1701 0.2973
Brugia malayi Voltage-gated potassium channel, Shaw-family (KCNC, Kv3-like) alpha-subunit 0.0038 0.0205 0.0322
Echinococcus multilocularis uncharacterized sodium dependent transporter 0.0044 0.0264 0.0258
Echinococcus multilocularis glutamate receptor ionotropic kainate 0.0074 0.0543 0.0537
Mycobacterium tuberculosis Probable soluble pyridine nucleotide transhydrogenase SthA (STH) (NAD(P)(+) transhydrogenase [B-specific]) (nicotinamide nucleot 0.0333 0.2939 0.5155
Echinococcus multilocularis adenylate cyclase 9 0.0083 0.0629 0.0623
Wolbachia endosymbiont of Brugia malayi dihydrolipoamide dehydrogenase E3 component 0.0333 0.2939 1
Plasmodium vivax multidomain scavenger receptor, putative 0.0042 0.0248 0.0413
Plasmodium falciparum ataxin-2 like protein, putative 0.0027 0.0107 0.0164
Loa Loa (eye worm) metabotropic glutamate receptor 8 0.0024 0.0083 0.014
Echinococcus granulosus transient receptor potential cation channel 0.0038 0.0205 0.0199
Echinococcus multilocularis rhodopsin orphan GPCR 0.0209 0.1793 0.1787
Mycobacterium leprae Probable NADH-dependent glutamate synthase (small subunit) GltD (L-glutamate synthase) (L-glutamate synthetase) (NADH-glutamate 0.0088 0.0675 0.1582
Loa Loa (eye worm) jmjC domain-containing protein 0.004 0.0223 0.0378
Trichomonas vaginalis voltage and ligand gated potassium channel, putative 0.0018 0.0019 0.0066
Echinococcus granulosus Glutamate receptor ionotropic kainate 2 0.0198 0.1688 0.1682
Echinococcus granulosus proto oncogene tyrosine protein kinase LCK 0.0041 0.0239 0.0232
Loa Loa (eye worm) hypothetical protein 0.0101 0.0795 0.1347
Leishmania major mitogen activated protein kinase 4, putative;with=GeneDB:LmxM19.1440 0.0055 0.0362 0.0464
Schistosoma mansoni coup transcription factor 0.0022 0.0057 0.0055
Loa Loa (eye worm) hypothetical protein 0.0209 0.1793 0.304
Loa Loa (eye worm) tyrosyl-DNA phosphodiesterase 0.0071 0.0511 0.0867
Echinococcus multilocularis apoptosis inducing factor 1 mitochondrial 0.0088 0.0675 0.0669
Trichomonas vaginalis aldehyde oxidase, putative 0.0185 0.1574 0.5357
Mycobacterium leprae PROBABLE ENDONUCLEASE IV END (ENDODEOXYRIBONUCLEASE IV) (APURINASE) 0.0082 0.0617 0.1433
Echinococcus granulosus chromobox protein 1 0.0075 0.0548 0.0541
Brugia malayi Voltage-gated calcium channel, L-type, alpha subunit. C. elegans egl-19 ortholog 0.0138 0.1133 0.1784
Brugia malayi Phosphatidylinositol 3- and 4-kinase family protein 0.0048 0.0302 0.0476
Toxoplasma gondii DNA topoisomerase 2, putative 0.015 0.1242 0.2165
Plasmodium falciparum type II NADH:ubiquinone oxidoreductase 0.0088 0.0675 0.1166
Trypanosoma cruzi ferric reductase transmembrane protein, putative 0.0036 0.0195 0.0246
Schistosoma mansoni neuropeptide receptor 0.0209 0.1793 0.1932
Loa Loa (eye worm) isocitrate dehydrogenase 0.0017 0.0014 0.0023
Echinococcus granulosus geminin 0.0181 0.1537 0.1531
Echinococcus multilocularis NADP dependent isocitrate dehydrogenase 0.0017 0.0014 0.0007
Leishmania major hypothetical protein, conserved 0.0088 0.0675 0.0873
Echinococcus multilocularis nmda type glutamate receptor 0.0199 0.1699 0.1694
Brugia malayi Large-conductance calcium-activated potassium channel Slo-1 (KCNMA) alpha subunit. C. elegans slo-1 ortholog 0.0038 0.0205 0.0322
Echinococcus multilocularis peregrin 0.0031 0.0146 0.014
Echinococcus granulosus intermediate filament protein 0.0029 0.0124 0.0118
Echinococcus multilocularis glutamate (NMDA) receptor subunit 0.035 0.3103 0.3099
Brugia malayi Sodium:neurotransmitter symporter family protein 0.0044 0.0264 0.0415
Mycobacterium tuberculosis Probable carbon monoxyde dehydrogenase (large chain) 0.0087 0.0667 0.1151
Echinococcus granulosus hypothetical protein 0.0038 0.0205 0.0199
Echinococcus granulosus glutamate synthase 0.0088 0.0675 0.0669
Treponema pallidum quinoline 2-oxidoreductase 0.0029 0.013 0.0298
Entamoeba histolytica tyrosyl-DNA phosphodiesterase, putative 0.0071 0.0511 0.1726
Mycobacterium tuberculosis Probable oxidoreductase 0.0444 0.3965 0.6963
Loa Loa (eye worm) nuclear hormone receptor family member nhr-41 0.0022 0.0057 0.0097
Loa Loa (eye worm) hypothetical protein 0.0253 0.2201 0.3732
Echinococcus multilocularis serotonin receptor 0.047 0.4207 0.4203
Plasmodium falciparum transporter, putative 0.0044 0.0264 0.0441
Brugia malayi DNA topoisomerase II, alpha isozyme 0.015 0.1242 0.1956
Echinococcus granulosus transcription factor Dp 1 0.0041 0.0236 0.0229
Loa Loa (eye worm) cytochrome P450 family protein 0.0021 0.0049 0.0083
Brugia malayi intermediate filament protein 0.0029 0.0124 0.0195
Schistosoma mansoni disulfide oxidoreductase 0.0088 0.0675 0.0723
Echinococcus multilocularis musashi 0.0029 0.0124 0.0118
Trypanosoma cruzi NADH dehydrogenase, putative 0.0088 0.0675 0.0873
Schistosoma mansoni tyrosine kinase 0.0161 0.1346 0.1448
Trypanosoma cruzi inositol 1,4,5-trisphosphate receptor, putative 0.0038 0.0205 0.0259
Loa Loa (eye worm) hypothetical protein 0.0209 0.1793 0.304
Schistosoma mansoni voltage-gated potassium channel 0.0041 0.0239 0.0251
Trichomonas vaginalis glucosylceramidase, putative 0.0276 0.2417 0.8222
Loa Loa (eye worm) gonadotropin-releasing hormone receptor 2 0.0209 0.1793 0.304
Echinococcus multilocularis sulfide:quinone oxidoreductase 0.0088 0.0675 0.0669
Onchocerca volvulus 0.0209 0.1793 0.7902
Echinococcus multilocularis transient receptor potential cation channel 0.0038 0.0205 0.0199
Schistosoma mansoni sulfide quinone reductase 0.0088 0.0675 0.0723
Trypanosoma cruzi pyridine nucleotide-disulphide oxidoreductase, putative 0.0088 0.0675 0.0873
Loa Loa (eye worm) voltage-gated calcium channel 0.0038 0.0205 0.0347
Brugia malayi Protein kinase domain containing protein 0.0052 0.034 0.0535
Brugia malayi Pyridine nucleotide-disulphide oxidoreductase family protein 0.0088 0.0675 0.1063
Brugia malayi metabotropic glutamate receptor type 2 0.0024 0.0083 0.013
Echinococcus multilocularis neuropeptide receptor 0.0209 0.1793 0.1787
Echinococcus multilocularis tyrosine kinase 0.0026 0.0102 0.0095
Onchocerca volvulus 0.0209 0.1793 0.7902
Loa Loa (eye worm) hypothetical protein 0.0022 0.0057 0.0097
Schistosoma mansoni hyperpolarization activated cyclic nucleotide-gated potassium channel 0.0043 0.0253 0.0267
Schistosoma mansoni jumonji domain containing protein 0.0081 0.0609 0.0652
Treponema pallidum NADH oxidase 0.0333 0.2939 1
Echinococcus multilocularis sodium and chloride dependent glycine 0.0044 0.0264 0.0258
Trichomonas vaginalis dihydroorotate dehydrogenase, putative 0.0088 0.0675 0.2297
Chlamydia trachomatis glutamine binding protein 0.004 0.0232 0.0501
Echinococcus granulosus dnaJ subfamily B 0.0438 0.3911 0.3907
Loa Loa (eye worm) hypothetical protein 0.0042 0.0248 0.042
Trichomonas vaginalis PIKK family atypical protein kinase 0.0036 0.0188 0.0641
Plasmodium falciparum DNA topoisomerase 2 0.015 0.1242 0.2165
Mycobacterium tuberculosis Possible dehydrogenase/reductase 0.0088 0.0675 0.1166
Mycobacterium ulcerans NADH dehydrogenase Ndh1 0.0088 0.0675 0.2181
Loa Loa (eye worm) serotonin transporter b 0.0259 0.2254 0.3822
Schistosoma mansoni glutamate synthase 0.0088 0.0675 0.0723
Onchocerca volvulus Dopamine\/Ecdysteroid receptor homolog 0.0209 0.1793 0.7902
Trypanosoma cruzi mitogen activated protein kinase 4, putative 0.0055 0.0362 0.0464
Loa Loa (eye worm) hypothetical protein 0.0259 0.2254 0.3822
Onchocerca volvulus 0.0209 0.1793 0.7902
Echinococcus multilocularis NADPH:adrenodoxin oxidoreductase 0.0088 0.0675 0.0669
Brugia malayi ERG2 and Sigma1 receptor like protein 0.0394 0.3507 0.552
Echinococcus multilocularis voltage gated potassium channel 0.0038 0.0205 0.0199
Schistosoma mansoni NADP-specific isocitrate dehydrogenase 0.0017 0.0014 0.0008
Loa Loa (eye worm) hypothetical protein 0.0042 0.0248 0.042
Schistosoma mansoni FTZ-F1 nuclear receptor-like protein 0.0022 0.0057 0.0055
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0022 0.0057 0.0051
Schistosoma mansoni opsin-like receptor 0.0209 0.1793 0.1932
Loa Loa (eye worm) hypothetical protein 0.0038 0.0205 0.0347
Echinococcus granulosus metabotropic glutamate receptor 2 0.0024 0.0083 0.0077
Brugia malayi Serotonin receptor 0.0209 0.1793 0.2822
Echinococcus granulosus rhodopsin orphan GPCR 0.0209 0.1793 0.1787
Trypanosoma brucei PAB1-binding protein , putative 0.0027 0.0107 0.0131
Trypanosoma cruzi dihydrolipoyl dehydrogenase, putative 0.0333 0.2939 0.3829
Trypanosoma brucei cytochrome P450, putative 0.0021 0.0049 0.0056
Loa Loa (eye worm) metabotropic GABA-B receptor subtype 2 0.0024 0.0083 0.014
Trichomonas vaginalis dihydrolipoamide dehydrogenase, putative 0.0088 0.0675 0.2297
Brugia malayi Cytochrome P450 family protein 0.0021 0.0049 0.0077
Loa Loa (eye worm) hypothetical protein 0.047 0.4207 0.7134
Loa Loa (eye worm) hypothetical protein 0.0024 0.0083 0.014
Echinococcus granulosus Glutamate receptor ionotropic kainate 2 0.0198 0.1688 0.1682
Schistosoma mansoni ryanodine receptor related 0.0038 0.0205 0.0215
Schistosoma mansoni amine GPCR 0.0209 0.1793 0.1932
Leishmania major dihydrolipoamide dehydrogenase, putative 0.0333 0.2939 0.3829
Brugia malayi Latrophilin receptor protein 2 0.0017 0.0013 0.0021
Trichomonas vaginalis ap endonuclease, putative 0.002 0.0043 0.0148
Echinococcus multilocularis CalModulin family member (cmd 1) 0.0026 0.01 0.0093
Trichomonas vaginalis CMGC family protein kinase 0.0055 0.0362 0.1232
Echinococcus multilocularis transient receptor potential cation channel 0.0038 0.0208 0.0201
Echinococcus multilocularis Glutamate receptor, ionotropic kainate 2 0.0198 0.1688 0.1682
Echinococcus multilocularis thyroid hormone receptor alpha 0.0022 0.0057 0.0051
Schistosoma mansoni intermediate filament proteins 0.0029 0.0124 0.0128
Schistosoma mansoni photoreceptor-specific nuclear receptor related 0.0022 0.0057 0.0055
Leishmania major apurinic/apyrimidinic endonuclease-redox protein 0.002 0.0043 0.0048
Echinococcus granulosus voltage dependent calcium channel 0.0057 0.038 0.0374
Loa Loa (eye worm) hypothetical protein 0.0038 0.0205 0.0347
Entamoeba histolytica hypothetical protein 0.0024 0.0083 0.0146
Echinococcus granulosus sodium:chloride dependent neurotransmitter 0.0044 0.0264 0.0258
Echinococcus granulosus g protein linked acetylcholine receptor gar 2a 0.0209 0.1793 0.1787
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0209 0.1793 0.1932
Mycobacterium leprae Probable NADPH:adrenodoxin oxidoreductase FprA (NADPH-FERREDOXIN REDUCTASE) 0.0088 0.0675 0.1582
Loa Loa (eye worm) hypothetical protein 0.0029 0.0124 0.021
Trypanosoma cruzi mitochondrial DNA topoisomerase II, putative 0.0168 0.1412 0.1835
Loa Loa (eye worm) 5-hydroxytryptamine 2C receptor 0.0209 0.1793 0.304
Wolbachia endosymbiont of Brugia malayi dihydrolipoamide dehydrogenase E3 component 0.0333 0.2939 1
Trichomonas vaginalis disulfide oxidoreductase, putative 0.0088 0.0675 0.2297
Trichomonas vaginalis PIKK family atypical protein kinase 0.0048 0.0302 0.1029
Schistosoma mansoni myosin xvIII 0.0209 0.1793 0.1932
Schistosoma mansoni histamine h1 receptor 0.0209 0.1793 0.1932
Echinococcus multilocularis sodium:chloride dependent neurotransmitter 0.0044 0.0264 0.0258
Echinococcus multilocularis geminin 0.0181 0.1537 0.1531
Echinococcus multilocularis COUP TF:Svp nuclear hormone receptor 0.0022 0.0057 0.0051
Trichomonas vaginalis PIKK family atypical protein kinase 0.0026 0.0098 0.0332
Trichomonas vaginalis glucosylceramidase, putative 0.0181 0.1537 0.5228
Loa Loa (eye worm) cytochrome P450 family protein 0.0021 0.0049 0.0083
Onchocerca volvulus 0.0209 0.1793 0.7902
Plasmodium vivax DNA topoisomerase II, putative 0.015 0.1242 0.2165
Plasmodium falciparum AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.002 0.0043 0.0053
Loa Loa (eye worm) hypothetical protein 0.0044 0.0264 0.0447
Trypanosoma brucei FAT domain/Rapamycin binding domain/Phosphatidylinositol 3- and 4-kinase, putative 0.002 0.0042 0.0047
Chlamydia trachomatis arginine ABC transporter substrate-binding protein ArtJ 0.004 0.0232 0.0501
Mycobacterium ulcerans DNA gyrase subunit B 0.0087 0.0665 0.2146
Echinococcus granulosus biogenic amine 5HT receptor 0.047 0.4207 0.4203
Echinococcus granulosus transient receptor potential gamma protein 0.0038 0.0205 0.0199
Echinococcus multilocularis sex peptide receptor 0.0209 0.1793 0.1787
Echinococcus granulosus insulin receptor 0.0052 0.034 0.0334
Brugia malayi Dopamine receptor protein 1, putative (partial) 0.0209 0.1793 0.2822
Loa Loa (eye worm) hypothetical protein 0.0525 0.4724 0.8011
Echinococcus multilocularis G protein coupled receptor 139 0.0209 0.1793 0.1787
Loa Loa (eye worm) hypothetical protein 0.0022 0.0057 0.0097
Mycobacterium ulcerans NADH dehydrogenase Ndh 0.0088 0.0675 0.2181
Leishmania major hypothetical protein, unknown function 0.0038 0.0205 0.0259
Echinococcus granulosus survival motor neuron protein 1 0.0253 0.2201 0.2196
Brugia malayi AKH receptor 0.0209 0.1793 0.2822
Loa Loa (eye worm) hypothetical protein 0.0209 0.1793 0.304
Schistosoma mansoni hypothetical protein 0.0209 0.1793 0.1932
Echinococcus multilocularis diuretic hormone 44 receptor GPRdih2 0.0017 0.0013 0.0007
Echinococcus granulosus serotonin receptor 0.0209 0.1793 0.1787
Loa Loa (eye worm) hypothetical protein 0.0038 0.0205 0.0347
Trichomonas vaginalis conserved hypothetical protein 0.0016 0.0005 0.0016
Brugia malayi DNA-(Apurinic or apyrimidinic site) lyase 0.0082 0.0617 0.0971
Mycobacterium ulcerans NADPH dependent 2,4-dienoyl-CoA reductase FadH 0.0088 0.0675 0.2181
Brugia malayi Sodium:neurotransmitter symporter family protein 0.0044 0.0264 0.0415
Brugia malayi ORL1-like opioid receptor 0.0209 0.1793 0.2822
Echinococcus granulosus lamin 0.0029 0.0124 0.0118
Trichomonas vaginalis PIKK family atypical protein kinase 0.0026 0.0098 0.0332
Echinococcus granulosus potassium large conductance calcium activated 0.0038 0.0205 0.0199
Schistosoma mansoni voltage-gated cation channel 0.0138 0.1133 0.1219
Schistosoma mansoni voltage-gated potassium channel 0.0046 0.0287 0.0303
Echinococcus granulosus voltage dependent L type calcium channel subunit|voltage dependent calcium channel 0.0138 0.1133 0.1128
Echinococcus multilocularis GPCR, family 2 0.0017 0.0013 0.0007
Loa Loa (eye worm) hypothetical protein 0.0026 0.0102 0.0172
Echinococcus multilocularis tachykinin peptides receptor 99D 0.0209 0.1793 0.1787
Echinococcus multilocularis fmrfamide receptor 0.0209 0.1793 0.1787
Loa Loa (eye worm) hypothetical protein 0.0038 0.0208 0.0351
Treponema pallidum thioredoxin reductase (trxB) 0.0088 0.0675 0.2181
Schistosoma mansoni glutamate synthase 0.0088 0.0675 0.0723
Loa Loa (eye worm) PHD-finger family protein 0.0031 0.0146 0.0247
Echinococcus multilocularis rhodopsin orphan GPCR 0.0209 0.1793 0.1787
Toxoplasma gondii histone lysine methyltransferase SET1 0.0059 0.0407 0.0693
Echinococcus multilocularis potassium voltage gated channel subfamily C 0.0038 0.0205 0.0199
Echinococcus granulosus two pore calcium channel protein 1 0.0038 0.0205 0.0199
Trypanosoma cruzi dihydrolipoyl dehydrogenase, putative 0.0333 0.2939 0.3829
Schistosoma mansoni amine GPCR 0.0209 0.1793 0.1932
Schistosoma mansoni voltage-gated potassium channel 0.0078 0.058 0.062
Echinococcus granulosus NADP dependent isocitrate dehydrogenase 0.0017 0.0014 0.0007
Wolbachia endosymbiont of Brugia malayi fructose-1,6-bisphosphatase 0.004 0.0223 0.062
Schistosoma mansoni hypothetical protein 0.0017 0.0013 0.0008
Treponema pallidum fructose-bisphosphate aldolase 0.0313 0.2754 0.936
Echinococcus granulosus tumor protein p63 0.0362 0.3206 0.3202
Onchocerca volvulus 0.0089 0.0681 0.2842
Plasmodium falciparum thioredoxin reductase 0.0333 0.2939 0.5155
Echinococcus multilocularis DNA (apurinic or apyrimidinic site) lyase 0.002 0.0043 0.0037
Trichomonas vaginalis ap endonuclease, putative 0.002 0.0043 0.0148
Schistosoma mansoni hypothetical protein 0.0017 0.0013 0.0008
Loa Loa (eye worm) hypothetical protein 0.0024 0.0083 0.014
Trypanosoma cruzi PAB1-binding protein , putative 0.0027 0.0107 0.0131
Plasmodium falciparum amino acid transporter, putative 0.0044 0.0264 0.0441
Loa Loa (eye worm) receptor family ligand binding region containing protein 0.0024 0.0083 0.014
Echinococcus granulosus apoptosis inducing factor 1 mitochondrial 0.0088 0.0675 0.0669
Echinococcus granulosus potassium voltage gated channel subfamily D 0.0038 0.0205 0.0199
Echinococcus multilocularis potassium:sodium hyperpolarization activated 0.0043 0.0253 0.0247
Loa Loa (eye worm) hypothetical protein 0.0138 0.1133 0.1922
Schistosoma mansoni nuclear hormone receptor nor-1/nor-2 0.0022 0.0057 0.0055
Echinococcus multilocularis conserved hypothetical protein 0.0038 0.0205 0.0199
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0313 0.2754 0.9369
Plasmodium vivax amine transporter, putative 0.0044 0.0264 0.0441
Schistosoma mansoni cpg binding protein 0.0031 0.0142 0.0146
Loa Loa (eye worm) hypothetical protein 0.0061 0.0421 0.0713
Trichomonas vaginalis PIKK family atypical protein kinase 0.0026 0.0097 0.0331
Echinococcus granulosus rhodopsin orphan GPCR 0.0209 0.1793 0.1787
Leishmania major hypothetical protein, conserved 0.0038 0.0205 0.0259
Echinococcus multilocularis transient receptor potential cation channel 0.0038 0.0205 0.0199
Echinococcus granulosus Glutamate receptor ionotropic kainate 2 0.0198 0.1688 0.1682
Toxoplasma gondii hypothetical protein 0.0019 0.0032 0.0033
Brugia malayi hypothetical protein 0.0209 0.1793 0.2822
Onchocerca volvulus 0.0053 0.0347 0.1322
Schistosoma mansoni peptide (FMRFamide/neurokinin-3)-like receptor 0.0209 0.1793 0.1932
Plasmodium vivax DNA gyrase subunit A, putative 0.0032 0.0155 0.0249
Loa Loa (eye worm) nuclear hormone receptor family member nhr-14 0.0022 0.0057 0.0097
Loa Loa (eye worm) hepatopoietin HPO2 0.0037 0.0197 0.0334
Echinococcus granulosus sodium channel protein 0.0456 0.4077 0.4073
Plasmodium falciparum thioredoxin reductase 0.063 0.5689 1
Brugia malayi hypothetical protein 0.0209 0.1793 0.2822
Brugia malayi Pre-SET motif family protein 0.0033 0.0159 0.025
Echinococcus granulosus growth hormone secretagogue receptor type 1 0.0209 0.1793 0.1787
Echinococcus granulosus fmrfamide receptor 0.0209 0.1793 0.1787
Brugia malayi putative neuropeptide receptor 0.0209 0.1793 0.2822
Schistosoma mansoni neuropeptide F-like receptor 0.0209 0.1793 0.1932
Loa Loa (eye worm) thioredoxin reductase 0.063 0.5689 0.9648
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0019 0.0035 0.0118
Trichomonas vaginalis PIKK family atypical protein kinase 0.0028 0.0121 0.041
Loa Loa (eye worm) hypothetical protein 0.0525 0.4724 0.8011
Loa Loa (eye worm) hypothetical protein 0.0087 0.0667 0.113
Echinococcus granulosus ryanodine receptor 44f 0.0038 0.0205 0.0199
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0019 0.0035 0.0118
Toxoplasma gondii inositol(myo)-1(or 4)-monophosphatase 2, putative 0.004 0.0223 0.0369
Echinococcus multilocularis pyridine nucleotide disulfide oxidoreductase 0.0088 0.0675 0.0669
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0313 0.2754 0.9369
Trichomonas vaginalis myo inositol monophosphatase, putative 0.004 0.0223 0.0759
Schistosoma mansoni neuropeptide F-like receptor 0.0209 0.1793 0.1932
Echinococcus granulosus g-protein coupled receptor 0.0209 0.1793 0.1787
Echinococcus granulosus Transcription factor JmjC domain containing protein 0.0102 0.0803 0.0798
Onchocerca volvulus Putative DNA topoisomerase 2, mitochondrial 0.0101 0.0793 0.3352
Brugia malayi Dopamine receptor protein 1 0.0652 0.5896 0.9282
Echinococcus multilocularis FTZ F1 nuclear receptor protein 0.0022 0.0057 0.0051
Loa Loa (eye worm) hypothetical protein 0.0209 0.1793 0.304
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0033 0.0159 0.0165
Trypanosoma brucei apurinic/apyrimidinic endonuclease, putative 0.002 0.0043 0.0048
Schistosoma mansoni high voltage-activated calcium channel Cav1 0.0138 0.1133 0.1219
Onchocerca volvulus 0.0044 0.0264 0.0942
Trichomonas vaginalis PIKK family atypical protein kinase 0.0016 0.0006 0.0022
Mycobacterium tuberculosis Probable glutamine-binding lipoprotein GlnH (GLNBP) 0.004 0.0232 0.0384
Mycobacterium tuberculosis DNA gyrase (subunit B) GyrB (DNA topoisomerase (ATP-hydrolysing)) (DNA topoisomerase II) (type II DNA topoisomerase) 0.0087 0.0665 0.1148
Loa Loa (eye worm) doublecortin family protein 0.0042 0.0248 0.042
Entamoeba histolytica glutamate synthase beta subunit, putative 0.0088 0.0675 0.2331
Brugia malayi hypothetical protein 0.0209 0.1793 0.2822
Schistosoma mansoni transient receptor potential cation channel subfamily m member 0.0038 0.0205 0.0215
Echinococcus granulosus rhodopsin orphan GPCR 0.0209 0.1793 0.1787
Schistosoma mansoni glutamate receptor NMDA 0.0282 0.2469 0.2663
Trichomonas vaginalis PIKK family atypical protein kinase 0.0026 0.0097 0.0331
Brugia malayi Voltage-gated calcium channel, alpha subunit 0.0038 0.0205 0.0322
Loa Loa (eye worm) melatonin receptor type 1A 0.0209 0.1793 0.304
Brugia malayi Nuclear hormone receptor family member nhr-31 0.0022 0.0057 0.009
Echinococcus granulosus jumonji domain containing protein 0.0043 0.0259 0.0253
Loa Loa (eye worm) hypothetical protein 0.0038 0.0205 0.0347
Echinococcus multilocularis transfer RNA-Gly 0.0038 0.0205 0.0199
Schistosoma mansoni rab6-interacting 0.0042 0.0248 0.0261
Loa Loa (eye worm) hypothetical protein 0.0038 0.0205 0.0347
Loa Loa (eye worm) hypothetical protein 0.0209 0.1793 0.304
Loa Loa (eye worm) hypothetical protein 0.0209 0.1793 0.304
Brugia malayi Inositol-1 0.004 0.0223 0.0351
Echinococcus granulosus calmodulin 0.0026 0.01 0.0093
Mycobacterium ulcerans endonuclease IV 0.0082 0.0617 0.198
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0022 0.0057 0.009
Schistosoma mansoni growth hormone secretagogue receptor 0.0209 0.1793 0.1932
Echinococcus multilocularis tyrosine protein kinase Fyn 0.0037 0.0202 0.0196
Loa Loa (eye worm) cyclic-nucleotide gated cation channel 0.0043 0.0253 0.0429
Trichomonas vaginalis PIKK family atypical protein kinase 0.0026 0.0098 0.0332
Echinococcus multilocularis proto oncogene tyrosine protein kinase LCK 0.0041 0.0239 0.0232
Echinococcus granulosus potassium voltage gated channel subfamily H 0.0046 0.0287 0.0281
Loa Loa (eye worm) O-glycosyl hydrolase family 30 protein 0.0276 0.2417 0.4098
Leishmania major target of rapamycin kinase (TOR) kinase 3 0.0038 0.0212 0.0268
Schistosoma mansoni cpg binding protein 0.0032 0.0158 0.0164
Trichomonas vaginalis chromobox protein, putative 0.0075 0.0548 0.1863
Echinococcus granulosus potassium voltage gated channel protein 0.0038 0.0205 0.0199
Echinococcus multilocularis FAD linked sulfhydryl oxidase ALR 0.0037 0.0197 0.0191
Echinococcus multilocularis lysine specific demethylase 5A 0.0038 0.0207 0.0201
Echinococcus multilocularis PHD finger protein rhinoceros 0.0031 0.0146 0.014
Trypanosoma cruzi calmodulin, putative 0.0026 0.01 0.0122
Echinococcus granulosus lysine specific demethylase 5A 0.004 0.0223 0.0217
Echinococcus granulosus orexin receptor type 2 0.0209 0.1793 0.1787
Loa Loa (eye worm) adenylyl cyclase 3 0.0083 0.0629 0.1067
Brugia malayi aminoadipate-semialdehyde dehydrogenase-phosphopantetheinyl transferase 0.0089 0.0681 0.1072
Echinococcus granulosus cyclic nucleotide gated cation channel alpha 3 0.0043 0.0253 0.0247
Echinococcus granulosus voltage dependent calcium channel 0.0138 0.1133 0.1128
Loa Loa (eye worm) hypothetical protein 0.0033 0.0159 0.0269
Schistosoma mansoni hypothetical protein 0.0017 0.0013 0.0008
Trichomonas vaginalis DNA topoisomerase II, putative 0.015 0.1242 0.4227
Trypanosoma brucei isocitrate dehydrogenase [NADP], mitochondrial precursor, putative 0.0017 0.0014 0.0009
Schistosoma mansoni biogenic amine receptor 0.0209 0.1793 0.1932
Trypanosoma cruzi ferric reductase transmembrane protein, putative 0.0036 0.0195 0.0246
Brugia malayi latrophilin 2 splice variant baaae 0.0036 0.0195 0.0306
Trichomonas vaginalis dihydroorotate dehydrogenase, putative 0.0088 0.0675 0.2297
Schistosoma mansoni voltage-gated potassium channel 0.0038 0.0205 0.0215
Trichomonas vaginalis chromobox protein, putative 0.0045 0.0274 0.0931
Brugia malayi bZIP transcription factor family protein 0.009 0.0689 0.1085
Onchocerca volvulus 0.0209 0.1793 0.7902
Schistosoma mansoni biogenic amine (5HT) receptor 0.1015 0.9254 1
Trypanosoma brucei target of rapamycin kinase 3, putative 0.0038 0.0212 0.0268
Brugia malayi nuclear hormone receptor 0.0022 0.0057 0.009
Mycobacterium tuberculosis Probable reductase 0.0199 0.1701 0.2973
Plasmodium vivax hypothetical protein, conserved 0.0044 0.0264 0.0441
Loa Loa (eye worm) neuropeptide F receptor 0.0209 0.1793 0.304
Schistosoma mansoni tyrosine kinase 0.0085 0.0643 0.0688
Brugia malayi Blistered cuticle protein 3 0.0078 0.0577 0.0908
Brugia malayi Voltage-gated potassium channel, Shab-family (KCNB, Kv2-like) alpha-subunit 0.0038 0.0205 0.0322
Toxoplasma gondii Erv1 / Alr family protein 0.0037 0.0197 0.0323
Loa Loa (eye worm) hypothetical protein 0.0259 0.2254 0.3822
Loa Loa (eye worm) hypothetical protein 0.0038 0.0205 0.0347
Schistosoma mansoni glutamate receptor kainate 0.0173 0.1462 0.1574
Leishmania major C-8 sterol isomerase-like protein 0.0394 0.3507 0.457
Mycobacterium ulcerans dehydrogenase 0.0088 0.0675 0.2181
Loa Loa (eye worm) Sodium:neurotransmitter symporter family protein 0.0044 0.0264 0.0447
Echinococcus multilocularis atrial natriuretic peptide receptor 0.0024 0.0083 0.0077
Loa Loa (eye worm) hypothetical protein 0.0033 0.0161 0.0272
Schistosoma mansoni cellular tumor antigen P53 0.0053 0.0347 0.0369
Trichomonas vaginalis glucosylceramidase, putative 0.0191 0.1627 0.5535
Toxoplasma gondii Sodium:neurotransmitter symporter family protein 0.0044 0.0264 0.0441
Toxoplasma gondii hypothetical protein 0.0038 0.0205 0.0337
Loa Loa (eye worm) hypothetical protein 0.0044 0.0264 0.0447
Schistosoma mansoni hyperpolarization activated cyclic nucleotide-gated potassium channel 0.0038 0.0205 0.0215
Loa Loa (eye worm) hypothetical protein 0.0209 0.1793 0.304
Trypanosoma cruzi NADH dehydrogenase, putative 0.0088 0.0675 0.0873
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0209 0.1793 0.1932
Trypanosoma cruzi C-8 sterol isomerase, putative 0.0394 0.3507 0.457
Brugia malayi Phosphatidylinositol 3- and 4-kinase family protein 0.0016 0.0006 0.001
Echinococcus multilocularis voltage dependent L type calcium channel subunit 0.0138 0.1133 0.1128
Giardia lamblia GTOR 0.0048 0.0302 0.0894
Schistosoma mansoni vesicular amine transporter 0.0038 0.0205 0.0215
Echinococcus multilocularis epidermal growth factor receptor 0.0161 0.1346 0.134
Brugia malayi hypothetical protein 0.0209 0.1793 0.2822
Echinococcus granulosus dihydropyrimidine dehydrogenase NADP 0.0088 0.0675 0.0669
Trypanosoma cruzi calmodulin 0.0026 0.01 0.0122
Echinococcus multilocularis dihydropyrimidine dehydrogenase (NADP+) 0.0088 0.0675 0.0669
Echinococcus multilocularis fmrfamide receptor 0.0209 0.1793 0.1787
Schistosoma mansoni loxhd1 0.0042 0.0248 0.0261
Loa Loa (eye worm) hypothetical protein 0.0209 0.1793 0.304
Brugia malayi Adenylyl cyclase protein 0.0083 0.0629 0.099
Brugia malayi Receptor family ligand binding region containing protein 0.0024 0.0083 0.013
Loa Loa (eye worm) hypothetical protein 0.0652 0.5896 1
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0209 0.1793 0.1932
Loa Loa (eye worm) hypothetical protein 0.0209 0.1793 0.304
Treponema pallidum hypothetical protein 0.003 0.0136 0.032
Toxoplasma gondii pyridine nucleotide-disulfide oxidoreductase domain-containing protein 0.0088 0.0675 0.1166
Loa Loa (eye worm) hypothetical protein 0.0088 0.0675 0.1145
Echinococcus granulosus neuropeptide s receptor 0.0701 0.6352 0.635
Loa Loa (eye worm) hypothetical protein 0.0209 0.1793 0.304
Mycobacterium ulcerans carbon monoxide dehydrogenase 0.0123 0.0995 0.3285
Schistosoma mansoni lamin 0.0029 0.0124 0.0128
Brugia malayi PHD-finger family protein 0.0031 0.0146 0.0229
Brugia malayi neuropeptide F receptor 0.0209 0.1793 0.2822
Loa Loa (eye worm) hypothetical protein 0.0042 0.0244 0.0414
Trypanosoma brucei inositol 1,4,5-trisphosphate receptor 0.0038 0.0205 0.0259
Brugia malayi Intermediate filament tail domain containing protein 0.0029 0.0124 0.0195
Schistosoma mansoni tyrosine kinase 0.0026 0.0102 0.0103
Entamoeba histolytica fructose-1,6-bisphosphate aldolase, putative 0.0313 0.2754 1
Onchocerca volvulus Glucosylceramidase homolog 0.0181 0.1537 0.6736
Schistosoma mansoni sodium-dependent neurotransmitter transporter 0.0044 0.0264 0.0278
Schistosoma mansoni hypothetical protein 0.0209 0.1793 0.1932
Brugia malayi Nuclear hormone receptor family member nhr-49 0.0022 0.0057 0.009
Plasmodium vivax type II NADH:ubiquinone oxidoreductase, putative 0.0088 0.0675 0.1166
Loa Loa (eye worm) glutamate receptor 1 0.0173 0.1462 0.2479
Mycobacterium ulcerans dihydrolipoamide dehydrogenase, LpdB 0.0333 0.2939 1
Loa Loa (eye worm) hypothetical protein 0.0027 0.0107 0.0181
Trypanosoma cruzi ERV/ALR sulfhydryl oxidase domain-containing protein 0.0037 0.0197 0.0249
Toxoplasma gondii CMGC kinase, MAPK family (ERK) MAPK-1 0.0055 0.0362 0.0614
Schistosoma mansoni voltage-gated potassium channel KCNQ 0.0038 0.0205 0.0215
Brugia malayi RE15519p 0.0209 0.1793 0.2822
Echinococcus multilocularis short transient receptor potential channel 6 0.0038 0.0205 0.0199
Brugia malayi Corticotropin releasing factor receptor 2 precursor, putative 0.0053 0.0351 0.0552
Echinococcus multilocularis somatostatin receptor 0.0209 0.1793 0.1787
Entamoeba histolytica NAD(FAD)-dependent dehydrogenase, putative 0.0088 0.0675 0.2331
Trichomonas vaginalis glucosylceramidase, putative 0.0276 0.2417 0.8222
Echinococcus granulosus glutamate receptor ionotropic kainate 0.0074 0.0543 0.0537
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0209 0.1793 0.1932
Echinococcus multilocularis Glutamate receptor, ionotropic kainate 2 0.0198 0.1688 0.1682
Echinococcus granulosus transient receptor potential cation channel 0.0038 0.0205 0.0199
Trichomonas vaginalis PIKK family atypical protein kinase 0.0016 0.0006 0.0022
Echinococcus multilocularis sodium channel protein 0.0497 0.4457 0.4453
Brugia malayi Sodium:neurotransmitter symporter family protein 0.0259 0.2254 0.3547
Toxoplasma gondii transporter, cation channel family protein 0.0057 0.038 0.0646
Trichomonas vaginalis voltage and ligand gated potassium channel, putative 0.0018 0.0019 0.0066
Entamoeba histolytica thioredoxin reductase, putative 0.0088 0.0675 0.2331
Trichomonas vaginalis CMGC family protein kinase 0.0055 0.0362 0.1232
Loa Loa (eye worm) neuropeptide F receptor 0.0209 0.1793 0.304
Echinococcus granulosus tyrosine protein kinase HCK 0.0033 0.0165 0.0159
Trypanosoma cruzi PAB1-binding protein , putative 0.0027 0.0107 0.0131
Brugia malayi SRC-1 0.0041 0.0239 0.0375
Echinococcus granulosus arachidonate 5 lipoxygenase 0.0185 0.1573 0.1568
Echinococcus granulosus FTZ F1 alpha 0.0022 0.0057 0.0051
Schistosoma mansoni tyrosine kinase 0.0052 0.034 0.0361
Loa Loa (eye worm) hypothetical protein 0.0038 0.0205 0.0347
Echinococcus granulosus transient receptor potential cation channel 0.0038 0.0205 0.0199
Loa Loa (eye worm) norepinephrine transporter 0.0259 0.2254 0.3822
Echinococcus granulosus L aminoadipate semialdehyde 0.0089 0.0681 0.0675
Schistosoma mansoni metabotropic glutamate receptor 0.0024 0.0083 0.0083
Echinococcus granulosus hyperpolarization activated cyclic 0.0043 0.0253 0.0247
Brugia malayi hypothetical protein 0.0209 0.1793 0.2822
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0763 0.6922 0.692
Echinococcus granulosus rhodopsin orphan GPCR 0.0209 0.1793 0.1787
Echinococcus granulosus Nuclear hormone receptor family member nhr 41 0.0022 0.0057 0.0051
Mycobacterium tuberculosis NADPH:adrenodoxin oxidoreductase FprA (NADPH-ferredoxin reductase) 0.0088 0.0675 0.1166
Trypanosoma cruzi trypanothione reductase, putative 0.063 0.5689 0.7419
Brugia malayi O-Glycosyl hydrolase family 30 protein 0.0276 0.2417 0.3804
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0016 0.0005 0.0016
Onchocerca volvulus Atrial natriuretic peptide receptor 3 homolog 0.003 0.0135 0.0354
Schistosoma mansoni two-pore calcium channel 0.0038 0.0205 0.0215
Leishmania major calcium channel protein, putative,ion transporter, putative 0.0456 0.4077 0.5315
Brugia malayi Probable DNA topoisomerase II 0.015 0.1242 0.1956
Schistosoma mansoni peptide (FMRFamide/somatostatin)-like receptor 0.0209 0.1793 0.1932
Trypanosoma brucei dihydrolipoyl dehydrogenase 0.0333 0.2939 0.3829
Loa Loa (eye worm) hypothetical protein 0.0209 0.1793 0.304
Echinococcus granulosus voltage gated hydrogen channel 1 0.0038 0.0205 0.0199
Trypanosoma brucei phosphatidylinositol 4-kinase, putative 0.0048 0.0302 0.0387
Schistosoma mansoni biogenic amine receptor 0.0209 0.1793 0.1932
Loa Loa (eye worm) hypothetical protein 0.0022 0.0057 0.0097
Schistosoma mansoni transient receptor potential cation channel subfamily m member 0.0038 0.0205 0.0215
Schistosoma mansoni hypothetical protein 0.0209 0.1793 0.1932
Loa Loa (eye worm) RGC/RGC protein kinase 0.003 0.0135 0.0228
Brugia malayi metabotropic GABA-B receptor subtype 2 0.0024 0.0083 0.013
Plasmodium vivax DNA gyrase subunit B, putative 0.0087 0.0665 0.1148
Schistosoma mansoni hypothetical protein 0.0036 0.0195 0.0204
Schistosoma mansoni hypothetical protein 0.0209 0.1793 0.1932
Mycobacterium leprae PROBABLE NADH DEHYDROGENASE NDH 0.0199 0.1701 0.4207
Schistosoma mansoni sodium/chloride dependent transporter 0.0044 0.0268 0.0283
Toxoplasma gondii DNA gyrase/topoisomerase IV, A subunit domain-containing protein 0.0032 0.0155 0.0249
Echinococcus multilocularis neuropeptide receptor 0.0209 0.1793 0.1787
Schistosoma mansoni sodium-dependent neurotransmitter transporter 0.0044 0.0264 0.0278
Loa Loa (eye worm) intermediate filament tail domain-containing protein 0.0029 0.0124 0.021
Schistosoma mansoni lamin 0.0029 0.0124 0.0128
Loa Loa (eye worm) hypothetical protein 0.0209 0.1793 0.304
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0209 0.1793 0.1932
Schistosoma mansoni inositol 145-trisphosphate receptor 0.0038 0.0205 0.0215
Brugia malayi Voltage-gated potassium channel, Shaker-family (KCNA, Kv1-like) alpha-subunit 0.0038 0.0205 0.0322
Echinococcus multilocularis cyclic nucleotide gated cation channel alpha 3 0.0043 0.0253 0.0247
Onchocerca volvulus Alhambra homolog 0.0031 0.0146 0.0406
Brugia malayi Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain containing protein 0.0244 0.2121 0.3339
Plasmodium falciparum holo-[acyl-carrier-protein] synthase, putative 0.0025 0.0089 0.0132
Brugia malayi hypothetical protein 0.0209 0.1793 0.2822
Schistosoma mansoni glutamate receptor kainate 0.0173 0.1462 0.1574
Echinococcus multilocularis calmodulin 0.0026 0.01 0.0093
Trichomonas vaginalis glucosylceramidase, putative 0.0181 0.1537 0.5228
Trypanosoma brucei trypanothione reductase 0.063 0.5689 0.7419
Schistosoma mansoni voltage-gated potassium channel 0.0038 0.0205 0.0215
Schistosoma mansoni ataxia telangiectasia mutated (atm)-related 0.0048 0.0302 0.032
Schistosoma mansoni tyrosyl-DNA phosphodiesterase 0.0071 0.0511 0.0546
Echinococcus multilocularis metabotropic glutamate receptor 2 0.0024 0.0083 0.0077
Echinococcus granulosus potassium voltage gated channel protein 0.0038 0.0205 0.0199
Echinococcus multilocularis tyrosine protein kinase HCK 0.0033 0.0165 0.0159
Trichomonas vaginalis PIKK family atypical protein kinase 0.0036 0.0188 0.0641
Echinococcus multilocularis neuropeptides capa receptor 0.0209 0.1793 0.1787
Trypanosoma cruzi DNA topoisomerase II, putative 0.0141 0.1168 0.1516
Echinococcus granulosus calmodulin 0.0026 0.01 0.0093
Leishmania major cytochrome p450-like protein 0.0021 0.0049 0.0056
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0656 0.593 0.7734
Toxoplasma gondii histone lysine methyltransferase SET/SUV39 0.0033 0.0159 0.0256
Chlamydia trachomatis DNA gyrase subunit A 0.0032 0.0155 0.0232
Plasmodium falciparum NAD(P)H-dependent glutamate synthase, putative 0.0088 0.0675 0.1166
Trypanosoma cruzi Present in the outer mitochondrial membrane proteome 4 0.0037 0.0197 0.0249
Echinococcus multilocularis voltage dependent calcium channel type d subunit 0.0138 0.1133 0.1128
Mycobacterium tuberculosis Putative ferredoxin reductase 0.0199 0.1701 0.2973
Schistosoma mansoni sodium/chloride dependent neurotransmitter transporter 0.0044 0.0264 0.0278
Schistosoma mansoni 60S ribosomal protein L21 0.0041 0.0239 0.0251
Schistosoma mansoni hypothetical protein 0.0038 0.0205 0.0215
Mycobacterium tuberculosis Probable NADH-dependent glutamate synthase (small subunit) GltD (L-glutamate synthase) (L-glutamate synthetase) (NADH-glutamate 0.0088 0.0675 0.1166
Echinococcus multilocularis two pore calcium channel protein 1 0.0038 0.0205 0.0199
Loa Loa (eye worm) hypothetical protein 0.0021 0.0047 0.008
Loa Loa (eye worm) hypothetical protein 0.0209 0.1793 0.304
Echinococcus granulosus G protein coupled 5 hydroxytryptamine receptor 0.0209 0.1793 0.1787
Echinococcus multilocularis peptide (allatostatin:somatostatin) 0.0209 0.1793 0.1787
Loa Loa (eye worm) hypothetical protein 0.0209 0.1793 0.304
Schistosoma mansoni glutamate receptor NMDA 0.035 0.3103 0.3349
Leishmania major mitochondrial DNA topoisomerase II 0.0168 0.1412 0.1835
Brugia malayi follicle stimulating hormone receptor 0.0209 0.1793 0.2822
Schistosoma mansoni dihydrolipoamide dehydrogenase 0.0333 0.2939 0.3171
Loa Loa (eye worm) phosphatidylinositol 3 0.0048 0.0302 0.0513
Echinococcus granulosus CalModulin family member cmd 1 0.0026 0.01 0.0093
Echinococcus granulosus potassium voltage gated channel subfamily H 0.0074 0.0547 0.054
Toxoplasma gondii endonuclease IV APN 0.0082 0.0617 0.1063
Loa Loa (eye worm) hypothetical protein 0.0038 0.0205 0.0347
Brugia malayi MAP kinase sur-1 0.0055 0.0362 0.057
Brugia malayi Voltage-gated potassium channel, KCNQ (Kv7-like) alpha-subunit. C. elegans kqt-1 ortholog 0.0038 0.0205 0.0322
Echinococcus granulosus sodium and chloride dependent glycine 0.0044 0.0264 0.0258
Loa Loa (eye worm) RGC/RGC protein kinase 0.003 0.0135 0.0228
Onchocerca volvulus 0.0052 0.0335 0.1267
Trichomonas vaginalis PIKK family atypical protein kinase 0.0029 0.0123 0.0419
Onchocerca volvulus 0.0024 0.0083 0.0119
Echinococcus granulosus g protein coupled receptor 0.0209 0.1793 0.1787
Leishmania major dihydrolipoamide dehydrogenase, putative 0.0843 0.7666 1
Loa Loa (eye worm) hypothetical protein 0.0024 0.0083 0.014
Leishmania major DNA topoisomerase ii 0.0141 0.1168 0.1516
Schistosoma mansoni hypothetical protein 0.0181 0.1537 0.1655
Entamoeba histolytica pyridine nucleotide-disulfide oxidoreductase family protein 0.0088 0.0675 0.2331
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0019 0.0035 0.0118
Mycobacterium leprae Probable DNA gyrase (subunit B) GyrB (DNA topoisomerase (ATP-hydrolysing)) (DNA topoisomerase II) (Type II DNA topoisomerase) 0.0039 0.0217 0.041
Leishmania major NADH dehydrogenase, putative 0.0088 0.0675 0.0873
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0313 0.2754 0.9369
Wolbachia endosymbiont of Brugia malayi DNA gyrase, topoisomerase II, B subunit, GyrB 0.0087 0.0665 0.2146
Mycobacterium tuberculosis Probable fructose-bisphosphate aldolase Fba 0.0153 0.1272 0.2218
Loa Loa (eye worm) TOPoisomerase family member 0.015 0.1242 0.2107
Trichomonas vaginalis conserved hypothetical protein 0.003 0.0131 0.0446
Trichomonas vaginalis xanthine dehydrogenase, putative 0.0185 0.1574 0.5357
Echinococcus multilocularis g-protein coupled receptor 0.0209 0.1793 0.1787
Trypanosoma cruzi DNA topoisomerase II, putative 0.0141 0.1168 0.1516
Echinococcus multilocularis transient receptor potential cation channel 0.0038 0.0208 0.0201
Onchocerca volvulus Transient receptor potential cation channel trpm homolog 0.0038 0.0205 0.0675
Echinococcus multilocularis tyrosine protein kinase Src42A 0.0041 0.0239 0.0232
Loa Loa (eye worm) hypothetical protein 0.0101 0.0795 0.1347
Echinococcus granulosus sodium and chloride dependent glycine 0.0044 0.0264 0.0258
Loa Loa (eye worm) hypothetical protein 0.0026 0.01 0.0169
Loa Loa (eye worm) hypothetical protein 0.0209 0.1793 0.304
Loa Loa (eye worm) SRC-1 0.0041 0.0239 0.0404
Leishmania major isocitrate dehydrogenase [NADP], mitochondrial precursor, putative 0.0017 0.0014 0.0009
Loa Loa (eye worm) voltage-gated potassium channel 0.0038 0.0205 0.0347
Schistosoma mansoni norepinephrine/norepinephrine transporter 0.0044 0.0264 0.0278
Mycobacterium leprae DIHYDROLIPOAMIDE DEHYDROGENASE LPD (LIPOAMIDE REDUCTASE (NADH)) (LIPOYL DEHYDROGENASE) (DIHYDROLIPOYL DEHYDROGENASE) (DIAPHORASE 0.0444 0.3965 1
Echinococcus multilocularis transcription factor Dp 1 0.0041 0.0236 0.0229
Echinococcus multilocularis potassium voltage gated channel subfamily D 0.0038 0.0205 0.0199
Brugia malayi hypothetical protein 0.0038 0.0205 0.0322
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0022 0.0057 0.009
Loa Loa (eye worm) hypothetical protein 0.0024 0.0083 0.014
Mycobacterium ulcerans monoxygenase 0.0088 0.0675 0.2181
Mycobacterium ulcerans glutamine-binding lipoprotein GlnH 0.004 0.0232 0.065
Trypanosoma cruzi mitogen-activated protein kinase 11, putative 0.0055 0.0362 0.0464
Schistosoma mansoni muscarinic acetylcholine (GAR) receptor 0.0209 0.1793 0.1932
Schistosoma mansoni inositol monophosphatase 0.004 0.0223 0.0234
Echinococcus granulosus FTZ F1 nuclear receptor protein 0.0022 0.0057 0.0051
Trichomonas vaginalis disulfide oxidoreductase, putative 0.0088 0.0675 0.2297
Loa Loa (eye worm) pyridine nucleotide-disufhide oxidoreductase 0.0088 0.0675 0.1145
Loa Loa (eye worm) nuclear Hormone Receptor family member 0.0022 0.0057 0.0097
Plasmodium falciparum DNA gyrase subunit B 0.0087 0.0665 0.1148
Loa Loa (eye worm) pre-SET domain-containing protein family protein 0.0223 0.1926 0.3266
Schistosoma mansoni cyclic-nucleotide-gated cation channel 0.0038 0.0205 0.0215
Brugia malayi ecdysteroid receptor 0.0022 0.0057 0.009
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0019 0.0035 0.0118
Schistosoma mansoni tyrosine kinase 0.0041 0.0239 0.0251
Mycobacterium tuberculosis Probable carbon monoxyde dehydrogenase (small chain) 0.0035 0.0185 0.0302
Echinococcus multilocularis two pore calcium channel protein 2 0.0038 0.0205 0.0199
Schistosoma mansoni norepinephrine/norepinephrine transporter 0.0044 0.0264 0.0278
Echinococcus granulosus glutamate receptor 2 0.0124 0.1002 0.0996
Loa Loa (eye worm) hypothetical protein 0.0022 0.0057 0.0097
Brugia malayi dihydrolipoyl dehydrogenase, mitochondrial precursor, putative 0.0333 0.2939 0.4627
Brugia malayi Sodium:neurotransmitter symporter family protein 0.0044 0.0264 0.0415
Trypanosoma brucei ERV/ALR sulfhydryl oxidase domain-containing protein 0.0037 0.0197 0.0249
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0209 0.1793 0.1932
Loa Loa (eye worm) hypothetical protein 0.0021 0.0047 0.008
Echinococcus granulosus 5'partial|histone lysine N methyltransferase SETDB2 0.0031 0.0142 0.0136
Echinococcus multilocularis rhodopsin orphan GPCR 0.0209 0.1793 0.1787
Trypanosoma brucei DNA topoisomerase II beta, putative 0.0141 0.1168 0.1516
Schistosoma mansoni alpha-1 adrenergic receptor 0.0209 0.1793 0.1932
Schistosoma mansoni hypothetical protein 0.0042 0.0248 0.0261
Echinococcus granulosus lipoxygenase domain containing protein 0.0042 0.0248 0.0242
Loa Loa (eye worm) hypothetical protein 0.0259 0.2254 0.3822
Loa Loa (eye worm) hypothetical protein 0.0053 0.0351 0.0595
Echinococcus multilocularis neuropeptide FF receptor 2 0.0209 0.1793 0.1787
Echinococcus granulosus uncharacterized sodium dependent transporter 0.0044 0.0264 0.0258
Loa Loa (eye worm) hypothetical protein 0.0209 0.1793 0.304
Loa Loa (eye worm) voltage-gated potassium channel 0.0038 0.0205 0.0347
Echinococcus multilocularis calcium activated potassium channel 0.0038 0.021 0.0203
Echinococcus granulosus voltage dependent calcium channel type d subunit|voltage dependent calcium channel|voltage dependent L type calcium channel subu 0.0138 0.1133 0.1128
Echinococcus multilocularis g protein coupled receptor 0.0209 0.1793 0.1787
Schistosoma mansoni microtubule-associated protein tau 0.0738 0.6697 0.7235
Echinococcus multilocularis potassium voltage gated channel subfamily KQT 0.0038 0.0205 0.0199
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0731 0.6626 0.8642
Loa Loa (eye worm) ion channel NompC 0.0038 0.0205 0.0347
Brugia malayi G protein-coupled receptor 0.0209 0.1793 0.2822
Loa Loa (eye worm) hypothetical protein 0.0209 0.1793 0.304
Schistosoma mansoni histamine-responsive GPCR (AAF21638) 0.0209 0.1793 0.1932
Brugia malayi CXXC zinc finger family protein 0.0031 0.0142 0.0223
Schistosoma mansoni voltage-dependent calcium channel 0.0038 0.0205 0.0215
Trichomonas vaginalis CMGC family protein kinase 0.0055 0.0362 0.1232
Brugia malayi Dopamine receptor protein 2 0.0209 0.1793 0.2822
Loa Loa (eye worm) hypothetical protein 0.0038 0.0205 0.0347
Echinococcus granulosus RUN 0.0042 0.0248 0.0242
Schistosoma mansoni amine GPCR 0.0209 0.1793 0.1932
Trichomonas vaginalis PIKK family atypical protein kinase 0.0032 0.0156 0.053
Plasmodium vivax apurinic/apyrimidinic endonuclease Apn1, putative 0.0082 0.0617 0.1063
Echinococcus multilocularis FTZ F1 alpha 0.0022 0.0057 0.0051
Loa Loa (eye worm) hypothetical protein 0.0038 0.0205 0.0347
Loa Loa (eye worm) glutamate receptor 2 0.0173 0.1462 0.2479
Loa Loa (eye worm) hypothetical protein 0.0089 0.0681 0.1155
Schistosoma mansoni bromodomain-containing nuclear protein 1 brd1 0.0031 0.0146 0.0151
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0313 0.2754 0.9369
Schistosoma mansoni hypothetical protein 0.0088 0.0675 0.0723
Echinococcus granulosus transient receptor potential cation channel 0.0038 0.0208 0.0201
Trichomonas vaginalis PIKK family atypical protein kinase 0.0031 0.0146 0.0498
Echinococcus multilocularis chromobox protein 1 0.0075 0.0548 0.0541
Trypanosoma cruzi mitogen-activated protein kinase 11, putative 0.0055 0.0362 0.0464
Trichomonas vaginalis voltage and ligand gated potassium channel, putative 0.0049 0.0313 0.1064
Echinococcus granulosus neuropeptide receptor 0.0209 0.1793 0.1787
Loa Loa (eye worm) hypothetical protein 0.0022 0.0057 0.0096
Trypanosoma cruzi myo-inositol-1(or 4)-monophosphatase 1, putative 0.004 0.0223 0.0283
Trichomonas vaginalis PIKK family atypical protein kinase 0.0041 0.0237 0.0808
Echinococcus multilocularis jumonji domain containing protein 0.0043 0.0259 0.0253
Echinococcus granulosus hyperpolarization activated cyclic 0.0043 0.0253 0.0247
Brugia malayi Glutamate receptor 2 precursor 0.0173 0.1462 0.2301
Onchocerca volvulus Heterochromatin protein 1 homolog 0.0042 0.0244 0.0853
Loa Loa (eye worm) nuclear hormone receptor family member nhr-49 0.0022 0.0057 0.0097
Echinococcus multilocularis potassium voltage gated channel subfamily H 0.0046 0.0287 0.0281
Plasmodium falciparum phd finger protein, putative 0.0031 0.0146 0.0233
Echinococcus granulosus g protein linked acetylcholine receptor gar 2a 0.0209 0.1793 0.1787
Echinococcus multilocularis calmodulin 0.0026 0.01 0.0093
Chlamydia trachomatis Ssodium-dependent amino acid transporter 0.0044 0.0264 0.0614
Schistosoma mansoni voltage-gated potassium channel 0.0038 0.0205 0.0215
Brugia malayi calmodulin 0.0026 0.01 0.0157
Loa Loa (eye worm) hypothetical protein 0.0044 0.0264 0.0447
Toxoplasma gondii PHD-finger domain-containing protein 0.0031 0.0146 0.0233
Echinococcus granulosus potassium channel KvQLT family member kqt 1 0.0038 0.0205 0.0199
Echinococcus granulosus TRP transient receptor potential channel 0.0038 0.0205 0.0199
Brugia malayi hypothetical protein 0.0017 0.0018 0.0028
Schistosoma mansoni jumonji/arid domain-containing protein 0.004 0.0223 0.0234
Brugia malayi Nuclear hormone receptor family member nhr-14 0.0022 0.0057 0.009
Echinococcus multilocularis tyrosine protein kinase Fgr 0.0041 0.0239 0.0232
Echinococcus multilocularis dnaJ subfamily B 0.0438 0.3911 0.3907
Echinococcus multilocularis mitogen activated protein kinase 3 0.0055 0.0362 0.0356
Echinococcus multilocularis potassium voltage gated channel protein 0.0038 0.0205 0.0199
Schistosoma mansoni hyperpolarization activated cyclic nucleotide-gated potassium channel 0.0043 0.0253 0.0267
Loa Loa (eye worm) hypothetical protein 0.0046 0.0287 0.0486
Brugia malayi Hypothetical 29.7 kDa protein C05D11.5 in chromosome III 0.0022 0.0057 0.0089
Echinococcus granulosus chromobox protein 1 0.0075 0.0548 0.0541
Echinococcus granulosus lamin dm0 0.0029 0.0124 0.0118
Echinococcus multilocularis lamin 0.0029 0.0124 0.0118
Brugia malayi Voltage-gated calcium channel, P/Q-type, alpha subunit. C. elegans unc-2 ortholog 0.0038 0.0205 0.0322
Echinococcus granulosus transient receptor potential cation channel 0.0038 0.0205 0.0199
Echinococcus multilocularis Ribosomal protein S1, RNA binding domain 0.0074 0.0543 0.0537
Plasmodium falciparum DNA gyrase subunit A 0.0032 0.0155 0.0249
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0313 0.2754 0.9369
Echinococcus multilocularis rhodopsin orphan GPCR 0.0209 0.1793 0.1787
Trypanosoma cruzi target of rapamycin kinase 3 0.0038 0.0212 0.0268
Trichomonas vaginalis PIKK family atypical protein kinase 0.0036 0.0188 0.0641
Trichomonas vaginalis glucosylceramidase, putative 0.0181 0.1537 0.5228
Plasmodium vivax dihydrolipoyl dehydrogenase, apicoplast, putative 0.0333 0.2939 0.5155
Trichomonas vaginalis PIKK family atypical protein kinase 0.0048 0.0302 0.1029
Mycobacterium leprae THIOREDOXIN TRXC (TRX) (MPT46) 0.0088 0.0675 0.1582
Schistosoma mansoni amine GPCR 0.0209 0.1793 0.1932
Brugia malayi Calcitonin receptor-like protein seb-1 0.0053 0.0351 0.0552
Echinococcus multilocularis dihydropyrimidine dehydrogenase (NADP+) 0.0088 0.0675 0.0669
Echinococcus granulosus short transient receptor potential channel 6 0.0038 0.0205 0.0199
Schistosoma mansoni hypothetical protein 0.0052 0.0335 0.0355
Echinococcus multilocularis voltage dependent L type calcium channel subunit 0.0138 0.1133 0.1128
Brugia malayi larval opioid receptor 0.0209 0.1793 0.2822
Loa Loa (eye worm) hypothetical protein 0.0209 0.1793 0.304
Chlamydia trachomatis DNA gyrase subunit B 0.0069 0.0495 0.1426
Schistosoma mansoni glutamate synthase 0.0088 0.0675 0.0723
Echinococcus multilocularis neuropeptide s receptor 0.0701 0.6352 0.635
Echinococcus multilocularis NMDA receptor 0.0074 0.0543 0.0537
Brugia malayi hypothetical protein 0.0209 0.1793 0.2822
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0022 0.0057 0.009
Schistosoma mansoni sodium-dependent neurotransmitter transporter 0.0044 0.0264 0.0278
Schistosoma mansoni voltage-gated ion channel 0.0038 0.0205 0.0215
Schistosoma mansoni peptide (allatostatin/somatostatin)-like receptor 0.0209 0.1793 0.1932
Wolbachia endosymbiont of Brugia malayi 4'-phosphopantetheinyl transferase 0.0025 0.0089 0.0157
Loa Loa (eye worm) hypothetical protein 0.0209 0.1793 0.304
Trypanosoma cruzi calmodulin, putative 0.0026 0.01 0.0122
Onchocerca volvulus Bile acid receptor homolog 0.0022 0.0057 0.0003
Echinococcus granulosus voltage gated potassium channel 0.0046 0.0287 0.0281
Trichomonas vaginalis CMGC family protein kinase 0.0055 0.0362 0.1232
Loa Loa (eye worm) hypothetical protein 0.0209 0.1793 0.304
Trichomonas vaginalis glucosylceramidase, putative 0.0181 0.1537 0.5228
Trichomonas vaginalis PIKK family atypical protein kinase 0.0038 0.0211 0.0719
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0209 0.1793 0.1932
Trichomonas vaginalis inositol monophosphatase, putative 0.004 0.0223 0.0759
Echinococcus multilocularis sodium leak channel non selective protein 0.0038 0.0205 0.0199
Giardia lamblia Glutamate synthase 0.0088 0.0675 0.2181
Loa Loa (eye worm) hypothetical protein 0.0209 0.1793 0.304
Treponema pallidum amino acid ABC transporter, periplasmic binding protein 0.004 0.0232 0.065
Echinococcus granulosus glutamate receptor subunit protein glur 0.0074 0.0543 0.0537
Brugia malayi GnHR receptor homolog 0.0209 0.1793 0.2822
Schistosoma mansoni neuropeptide f receptor 76f 0.0209 0.1793 0.1932
Toxoplasma gondii target of rapamycin (TOR), putative 0.0036 0.0188 0.0308
Loa Loa (eye worm) hypothetical protein 0.0028 0.0119 0.0202
Onchocerca volvulus 0.0033 0.0161 0.0472
Onchocerca volvulus 0.0083 0.0629 0.2606
Mycobacterium ulcerans dihydrolipoamide dehydrogenase 0.0333 0.2939 1
Trypanosoma brucei 2,4-dienoyl-coa reductase-like protein 0.0088 0.0675 0.0873
Echinococcus multilocularis serotonin transporter 0.0259 0.2254 0.2249
Trichomonas vaginalis PIKK family atypical protein kinase 0.0016 0.0006 0.0022
Loa Loa (eye worm) hypothetical protein 0.0036 0.0195 0.033
Brugia malayi Melatonin receptor type 1A 0.0209 0.1793 0.2822
Loa Loa (eye worm) blistered cuticle protein 3 0.0078 0.0577 0.0979
Echinococcus multilocularis potassium large conductance calcium activated 0.0038 0.0205 0.0199
Trypanosoma cruzi myo-inositol-1(or 4)-monophosphatase 1, putative 0.004 0.0223 0.0283
Trypanosoma cruzi 2,4-dienoyl-coa reductase-like protein, putative 0.0088 0.0675 0.0873
Echinococcus multilocularis glutamate receptor 2 0.0124 0.1002 0.0996
Echinococcus multilocularis neuropeptide receptor A26 0.0701 0.6352 0.635
Echinococcus granulosus Potassium voltage gated channel protein Shaw 0.0038 0.0205 0.0199
Trypanosoma cruzi hypothetical protein, conserved 0.0088 0.0675 0.0873
Brugia malayi olfactory channel protein osm-9 0.0038 0.0208 0.0326
Echinococcus granulosus rhodopsin orphan GPCR 0.0209 0.1793 0.1787
Echinococcus multilocularis biogenic amine (5HT) receptor 0.1015 0.9254 0.9253
Echinococcus multilocularis neuropeptide Y receptor 0.0209 0.1793 0.1787
Echinococcus multilocularis neuropeptides capa receptor 0.0209 0.1793 0.1787
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0209 0.1793 0.1932
Onchocerca volvulus Adenylate cyclase type 2 homolog 0.0083 0.0629 0.2606
Mycobacterium ulcerans ferredoxin reductase 0.0088 0.0675 0.2181
Echinococcus granulosus atrial natriuretic peptide receptor 0.0024 0.0083 0.0077
Echinococcus granulosus sodium dependent neurotransmitter transporter 0.0044 0.0264 0.0258

Activities

Activity type Activity value Assay description Source Reference
HSF (functional) = 0 ml Neutralization of colony - stimulating activity was determined by incubating supernatants from stromal cells stimulated by compound (1000 ng/mL) with an antibody raised against KC[38-72]. ChEMBL. 9288169
HSF (functional) = 2300000 ml HSF produced by bone marrow-derived stromal cell lines C6.4 on stimulation with the compound at (1000 ng/mL) was determined in vitro in an GM-CFC assay. ChEMBL. 9288169

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
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External resources for this compound

No external resources registered for this compound

Bibliographic References

1 literature reference was collected for this gene.

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