Detailed information for compound 401802

Basic information

Technical information
  • Name: Unnamed compound
  • MW: 987.176 | Formula: C45H70N12O11S
  • H donors: 7 H acceptors: 11 LogP: -0.84 Rotable bonds: 26
    Rule of 5 violations (Lipinski): 4
  • SMILES: CC(C[C@@H](C(=O)N1CCC[C@]21CC[C@H]1N(C2=O)[C@H](CS1)C(=O)N[C@H](C(=O)N1CCC[C@H]1C(=O)NCC(=O)O)C)NC(=O)[C@H]1CCCN1C(=O)[C@@H](NC(=O)[C@H]1CCCN1C(=O)C)CCCN=C(N)N)C
  • InChi: 1S/C45H70N12O11S/c1-25(2)22-29(52-38(63)32-13-8-20-55(32)41(66)28(10-5-17-48-44(46)47)51-37(62)31-12-6-18-53(31)27(4)58)42(67)56-21-9-15-45(56)16-14-34-57(43(45)68)33(24-69-34)39(64)50-26(3)40(65)54-19-7-11-30(54)36(61)49-23-35(59)60/h25-26,28-34H,5-24H2,1-4H3,(H,49,61)(H,50,64)(H,51,62)(H,52,63)(H,59,60)(H4,46,47,48)/t26-,28-,29-,30-,31+,32+,33+,34-,45-/m0/s1
  • InChiKey: UXGXWTNPWAMFTI-NNTRHYODSA-N  

Network

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Synonyms

No synonyms found for this compound

Targets

Known targets for this compound

No curated genes were found associated with this compound

Predicted pathogen targets for this compound

By orthology
No druggable targets predicted by orthology data
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity

Obtained from network model

Ranking Plot


Putative Targets List


Species Potential target Raw Global Species
Entamoeba histolytica hypothetical protein 0.0023 0.0103 0.0146
Mycobacterium ulcerans glutamine-binding lipoprotein GlnH 0.0039 0.0262 0.0644
Brugia malayi Dopamine receptor protein 1, putative (partial) 0.0135 0.1244 0.2018
Echinococcus multilocularis rhodopsin orphan GPCR 0.0135 0.1244 0.1244
Loa Loa (eye worm) hypothetical protein 0.004 0.0275 0.0447
Echinococcus granulosus cyclic nucleotide gated cation channel 0.0041 0.0285 0.0285
Schistosoma mansoni voltage-gated potassium channel 0.0041 0.0285 0.031
Echinococcus multilocularis potassium voltage gated channel subfamily H 0.0045 0.0321 0.0321
Schistosoma mansoni metabotropic glutamate receptor 0.0023 0.0103 0.0112
Brugia malayi hypothetical protein 0.0135 0.1244 0.2018
Plasmodium falciparum phd finger protein, putative 0.003 0.0171 0.023
Schistosoma mansoni tyrosine kinase 0.004 0.0269 0.0292
Echinococcus granulosus uncharacterized sodium dependent transporter 0.0042 0.0296 0.0296
Echinococcus granulosus Tubulin beta 2C chain 0.0026 0.0131 0.0131
Mycobacterium tuberculosis Probable NADPH dependent 2,4-dienoyl-CoA reductase FadH (2,4-dienoyl coenzyme A reductase) (4-enoyl-CoA reductase) 0.0086 0.0743 0.1162
Schistosoma mansoni bromodomain-containing nuclear protein 1 brd1 0.003 0.0171 0.0185
Echinococcus granulosus potassium channel KvQLT family member kqt 1 0.0036 0.0234 0.0234
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0301 0.2953 0.9285
Schistosoma mansoni sulfide quinone reductase 0.0086 0.0743 0.0807
Trichomonas vaginalis PIKK family atypical protein kinase 0.003 0.0171 0.0493
Echinococcus multilocularis GPCR, family 2 0.0016 0.0029 0.0029
Trypanosoma cruzi mitogen-activated protein kinase 11, putative 0.0053 0.0401 0.0463
Echinococcus multilocularis 0.0048 0.035 0.035
Trichomonas vaginalis chromobox protein, putative 0.0072 0.0599 0.1846
Schistosoma mansoni voltage-gated potassium channel 0.0036 0.0234 0.0254
Loa Loa (eye worm) TK/EGFR protein kinase 0.0155 0.145 0.2352
Brugia malayi CXXC zinc finger family protein 0.003 0.0166 0.0269
Trichomonas vaginalis CMGC family protein kinase 0.0053 0.0401 0.1221
Trichomonas vaginalis xanthine dehydrogenase, putative 0.0179 0.1695 0.5309
Trichomonas vaginalis DNA topoisomerase II, putative 0.0144 0.134 0.4189
Echinococcus multilocularis Polycystic kidney disease protein 0.0041 0.0279 0.0279
Loa Loa (eye worm) ryanodine receptor 0.0036 0.0234 0.0379
Loa Loa (eye worm) CYP4Cod1 0.002 0.0067 0.0109
Echinococcus multilocularis metabotropic glutamate receptor 5 0.0023 0.0103 0.0103
Plasmodium vivax apurinic/apyrimidinic endonuclease Apn1, putative 0.0079 0.0673 0.1048
Loa Loa (eye worm) hypothetical protein 0.0036 0.0234 0.0379
Echinococcus multilocularis neuropeptides capa receptor 0.0135 0.1244 0.1244
Loa Loa (eye worm) hypothetical protein 0.0031 0.0185 0.0299
Echinococcus granulosus growth hormone secretagogue receptor type 1 0.0135 0.1244 0.1244
Echinococcus granulosus voltage dependent calcium channel type d subunit|voltage dependent calcium channel|voltage dependent L type calcium channel subu 0.0133 0.1224 0.1224
Echinococcus multilocularis microtubule associated protein 2 0.0711 0.7159 0.7159
Echinococcus multilocularis potassium voltage gated channel subfamily A 0.0036 0.0234 0.0234
Loa Loa (eye worm) hypothetical protein 0.0036 0.0234 0.0379
Loa Loa (eye worm) hypothetical protein 0.0036 0.0234 0.0379
Schistosoma mansoni amine GPCR 0.0647 0.6498 0.706
Plasmodium falciparum AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.0019 0.0061 0.0052
Schistosoma mansoni amine GPCR 0.0135 0.1244 0.1352
Echinococcus multilocularis arachidonate 5 lipoxygenase 0.0178 0.1693 0.1693
Trichomonas vaginalis PIKK family atypical protein kinase 0.0016 0.0022 0.0022
Echinococcus multilocularis hyperpolarization activated cyclic 0.0041 0.0285 0.0285
Loa Loa (eye worm) hypothetical protein 0.0249 0.2419 0.3923
Loa Loa (eye worm) pigment dispersing factor receptor c 0.0051 0.0389 0.0632
Onchocerca volvulus 0.0135 0.1244 0.4987
Loa Loa (eye worm) glutamate receptor 1 0.0167 0.1574 0.2554
Loa Loa (eye worm) hypothetical protein 0.0041 0.0285 0.0462
Echinococcus granulosus uncharacterized sodium dependent transporter 0.0042 0.0296 0.0296
Loa Loa (eye worm) gonadotropin-releasing hormone receptor 2 0.0135 0.1244 0.2018
Loa Loa (eye worm) cytoplasmic intermediate filament protein 0.0015 0.0015 0.0025
Echinococcus granulosus potassium voltage gated channel subfamily A 0.0036 0.0234 0.0234
Schistosoma mansoni hypothetical protein 0.0135 0.1244 0.1352
Echinococcus multilocularis tyrosine protein kinase Fyn 0.0036 0.0231 0.0231
Brugia malayi hypothetical protein 0.0042 0.0296 0.048
Brugia malayi steroid hormone receptor 0.0021 0.0076 0.0123
Schistosoma mansoni ATP-binding cassette transporter 0.0167 0.1577 0.1713
Echinococcus granulosus allatostatin A receptor 0.0135 0.1244 0.1244
Echinococcus granulosus 5'partial|histone lysine N methyltransferase SETDB2 0.003 0.0166 0.0166
Toxoplasma gondii exonuclease III APE 0.0019 0.0061 0.0052
Echinococcus granulosus Nuclear hormone receptor family member nhr 41 0.0021 0.0076 0.0076
Echinococcus multilocularis two pore calcium channel protein 1 0.0036 0.0234 0.0234
Echinococcus granulosus tyrosine protein kinase Src64B 0.004 0.0269 0.0269
Trichomonas vaginalis PIKK family atypical protein kinase 0.0034 0.0216 0.0635
Schistosoma mansoni sodium/chloride dependent neurotransmitter transporter 0.0042 0.0296 0.0322
Brugia malayi dihydrolipoyl dehydrogenase, mitochondrial precursor, putative 0.0323 0.3179 0.5155
Echinococcus granulosus glutamate receptor 2 0.0119 0.1084 0.1084
Brugia malayi Metabotropic glutamate receptor precursor. 0.0023 0.0103 0.0167
Brugia malayi jmjC domain containing protein 0.0038 0.0253 0.041
Plasmodium vivax holo-[acyl-carrier-protein] synthase, putative 0.0024 0.011 0.0131
Giardia lamblia DNA topoisomerase II 0.0137 0.1263 0.3856
Mycobacterium ulcerans 4'-phosphopantetheinyl transferase 0.0024 0.011 0.0155
Loa Loa (eye worm) hypothetical protein 0.0086 0.0741 0.1203
Trichomonas vaginalis apoptosis inducing factor, putative 0.0086 0.0743 0.23
Loa Loa (eye worm) hypothetical protein 0.002 0.0065 0.0106
Schistosoma mansoni tyrosine kinase 0.0025 0.0123 0.0134
Plasmodium falciparum DNA gyrase subunit B 0.0084 0.0724 0.1132
Schistosoma mansoni voltage-gated potassium channel 0.0036 0.0234 0.0254
Loa Loa (eye worm) pre-SET domain-containing protein family protein 0.0215 0.207 0.3357
Brugia malayi hypothetical protein 0.0135 0.1244 0.2018
Brugia malayi protein-tyrosine kinase 0.0036 0.0231 0.0374
Trypanosoma brucei DNA topoisomerase ii 0.0162 0.1521 0.1829
Onchocerca volvulus Adenylate cyclase type 2 homolog 0.008 0.0686 0.2606
Echinococcus multilocularis biogenic amine (5HT) receptor 0.0911 0.9204 0.9204
Echinococcus granulosus serotonin receptor 0.0135 0.1244 0.1244
Echinococcus granulosus peptide allatostatin:somatostatin 0.0135 0.1244 0.1244
Echinococcus multilocularis Tubulin beta 2C chain 0.0026 0.0131 0.0131
Echinococcus granulosus sodium dependent neurotransmitter transporter 0.0042 0.0296 0.0296
Echinococcus multilocularis NADPH:adrenodoxin oxidoreductase 0.0086 0.0743 0.0743
Brugia malayi F/Y-rich N-terminus family protein 0.002 0.0068 0.0109
Trichomonas vaginalis PIKK family atypical protein kinase 0.0034 0.0216 0.0635
Schistosoma mansoni hypothetical protein 0.0016 0.0029 0.0031
Leishmania major hypothetical protein, conserved 0.0086 0.0743 0.0879
Echinococcus multilocularis serotonin transporter 0.0249 0.2419 0.2419
Echinococcus granulosus geminin 0.0175 0.1654 0.1654
Loa Loa (eye worm) blistered cuticle protein 3 0.0075 0.0631 0.1023
Trichomonas vaginalis voltage and ligand gated potassium channel, putative 0.0017 0.0036 0.0065
Schistosoma mansoni transient receptor potential channel 0.0036 0.0236 0.0256
Plasmodium falciparum glutathione reductase 0.0615 0.6166 1
Brugia malayi NADPH:adrenodoxin oxidoreductase, mitochondrial precursor 0.0086 0.0743 0.1204
Echinococcus multilocularis potassium voltage gated channel subfamily D 0.0036 0.0234 0.0234
Trypanosoma cruzi pyridine nucleotide-disulphide oxidoreductase, putative 0.0086 0.0743 0.0879
Echinococcus multilocularis glutamate receptor 2 0.0119 0.1084 0.1084
Chlamydia trachomatis arginine ABC transporter substrate-binding protein ArtJ 0.0039 0.0262 0.0497
Echinococcus granulosus inositol monophosphatase 1 0.0038 0.0253 0.0253
Echinococcus multilocularis potassium voltage gated channel subfamily C 0.0036 0.0234 0.0234
Trichomonas vaginalis disulfide oxidoreductase, putative 0.0086 0.0743 0.23
Echinococcus granulosus glutamate receptor ionotropic kainate 0.0071 0.0594 0.0594
Schistosoma mansoni jumonji/arid domain-containing protein 0.0038 0.0253 0.0274
Loa Loa (eye worm) glutamate receptor 2 0.0167 0.1574 0.2554
Echinococcus granulosus arachidonate 5 lipoxygenase 0.0178 0.1693 0.1693
Schistosoma mansoni neuropeptide receptor 0.0135 0.1244 0.1352
Loa Loa (eye worm) hypothetical protein 0.0027 0.0142 0.0231
Loa Loa (eye worm) hepatopoietin HPO2 0.0035 0.0225 0.0365
Mycobacterium ulcerans dihydrolipoamide dehydrogenase 0.0323 0.3179 1
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0031 0.0185 0.02
Onchocerca volvulus 0.008 0.0686 0.2606
Trichomonas vaginalis tubulin gamma chain, putative 0.0026 0.0131 0.0368
Toxoplasma gondii transporter, cation channel family protein 0.0036 0.0234 0.0333
Schistosoma mansoni norepinephrine/norepinephrine transporter 0.0042 0.0296 0.0322
Plasmodium falciparum DNA topoisomerase 2 0.0144 0.134 0.2136
Echinococcus granulosus 7tm_1 domain containing protein 0.0135 0.1244 0.1244
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0021 0.0076 0.0123
Echinococcus granulosus voltage gated potassium channel 0.0045 0.0321 0.0321
Trichomonas vaginalis CMGC family protein kinase 0.0053 0.0401 0.1221
Leishmania major beta tubulin 0.0026 0.0131 0.0134
Echinococcus granulosus DNA apurinic or apyrimidinic site lyase 0.0019 0.0061 0.0061
Echinococcus granulosus transient receptor potential cation channel 0.0036 0.0236 0.0236
Brugia malayi Glutamate receptor 2 precursor 0.0167 0.1574 0.2553
Echinococcus multilocularis dro:myosuppressin receptor 0.0135 0.1244 0.1244
Schistosoma mansoni peptide (allatostatin/somatostatin)-like receptor 0.0135 0.1244 0.1352
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0018 0.0052 0.0117
Echinococcus multilocularis voltage dependent L type calcium channel subunit 0.0133 0.1224 0.1224
Schistosoma mansoni hypothetical protein 0.005 0.0372 0.0404
Echinococcus granulosus tyrosine protein kinase Blk 0.0036 0.0231 0.0231
Trichomonas vaginalis glucosylceramidase, putative 0.0184 0.175 0.5486
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0135 0.1244 0.1352
Echinococcus granulosus dihydropyrimidine dehydrogenase NADP 0.0086 0.0743 0.0743
Loa Loa (eye worm) hypothetical protein 0.0067 0.0546 0.0886
Trichomonas vaginalis glucosylceramidase, putative 0.0175 0.1654 0.5181
Trichomonas vaginalis PIKK family atypical protein kinase 0.0025 0.0119 0.0329
Echinococcus granulosus glutamate receptor subunit protein glur 0.0071 0.0594 0.0594
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0634 0.6369 0.7742
Schistosoma mansoni voltage-gated potassium channel KCNQ 0.0036 0.0234 0.0254
Echinococcus multilocularis NMDA receptor 0.0071 0.0594 0.0594
Schistosoma mansoni cpg binding protein 0.0031 0.0183 0.0199
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0301 0.2953 0.9285
Echinococcus granulosus dro:myosuppressin receptor 0.0135 0.1244 0.1244
Trichomonas vaginalis PIKK family atypical protein kinase 0.0034 0.0216 0.0635
Trichomonas vaginalis PIKK family atypical protein kinase 0.0037 0.024 0.0713
Toxoplasma gondii pyridine nucleotide-disulfide oxidoreductase domain-containing protein 0.0086 0.0743 0.1162
Trichomonas vaginalis PIKK family atypical protein kinase 0.0046 0.0338 0.102
Schistosoma mansoni glutamate receptor kainate 0.0167 0.1574 0.171
Echinococcus multilocularis neuropeptide Y receptor 0.0135 0.1244 0.1244
Plasmodium vivax dihydrolipoyl dehydrogenase, apicoplast, putative 0.0323 0.3179 0.5132
Brugia malayi Corticotropin releasing factor receptor 2 precursor, putative 0.0051 0.0389 0.0631
Onchocerca volvulus 0.0086 0.0743 0.2847
Loa Loa (eye worm) hypothetical protein 0.0025 0.0123 0.02
Loa Loa (eye worm) hypothetical protein 0.0045 0.0321 0.0521
Echinococcus multilocularis mitogen activated protein kinase 3 0.0053 0.0401 0.0401
Brugia malayi hypothetical protein 0.0041 0.0279 0.0453
Echinococcus multilocularis transient receptor potential cation channel 0.0036 0.0234 0.0234
Trichomonas vaginalis PIKK family atypical protein kinase 0.0016 0.0022 0.0022
Echinococcus granulosus chromobox protein 1 0.0072 0.0599 0.0599
Brugia malayi Voltage-gated potassium channel, KCNQ (Kv7-like) alpha-subunit. C. elegans kqt-1 ortholog 0.0036 0.0234 0.0378
Echinococcus granulosus lamin dm0 0.0028 0.0148 0.0148
Echinococcus multilocularis lamin 0.0028 0.0148 0.0148
Leishmania major beta tubulin 0.0026 0.0131 0.0134
Schistosoma mansoni voltage-gated potassium channel 0.0036 0.0234 0.0254
Toxoplasma gondii PHD-finger domain-containing protein 0.003 0.0171 0.023
Loa Loa (eye worm) hypothetical protein 0.0042 0.0296 0.0481
Echinococcus granulosus two pore calcium channel protein 2 0.0036 0.0234 0.0234
Echinococcus granulosus tyrosine kinase|tyrosine protein kinase Fyn 0.0036 0.0231 0.0231
Echinococcus multilocularis proto oncogene tyrosine protein kinase LCK 0.004 0.0269 0.0269
Echinococcus multilocularis serotonin receptor 0.0386 0.382 0.382
Loa Loa (eye worm) nuclear hormone receptor family member nhr-1 0.0021 0.0076 0.0123
Schistosoma mansoni hypothetical protein 0.0016 0.0029 0.0031
Trichomonas vaginalis PIKK family atypical protein kinase 0.0025 0.0119 0.0329
Trypanosoma cruzi myo-inositol-1(or 4)-monophosphatase 1, putative 0.0038 0.0253 0.0282
Loa Loa (eye worm) hypothetical protein 0.0135 0.1244 0.2018
Echinococcus granulosus histone lysine methyltransferase setb 0.0031 0.0185 0.0185
Schistosoma mansoni lamin 0.0028 0.0148 0.016
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0135 0.1244 0.1352
Schistosoma mansoni sodium-dependent neurotransmitter transporter 0.0042 0.0296 0.0322
Loa Loa (eye worm) intermediate filament tail domain-containing protein 0.0028 0.0148 0.0239
Brugia malayi Ryanodine Receptor TM 4-6 family protein 0.0036 0.0234 0.0379
Brugia malayi Probable DNA topoisomerase II 0.0144 0.134 0.2173
Schistosoma mansoni transient receptor potential channel 4 0.0036 0.0234 0.0254
Trypanosoma brucei dihydrolipoyl dehydrogenase 0.0323 0.3179 0.385
Entamoeba histolytica DNA topoisomerase II, putative 0.0144 0.134 0.4424
Onchocerca volvulus 0.0135 0.1244 0.4987
Brugia malayi Furin-like cysteine rich region family protein 0.0155 0.145 0.2352
Schistosoma mansoni hypothetical protein 0.0135 0.1244 0.1352
Trypanosoma brucei phosphatidylinositol 4-kinase, putative 0.0046 0.0338 0.0385
Echinococcus granulosus tyrosine kinase 0.0036 0.0231 0.0231
Plasmodium vivax DNA gyrase subunit B, putative 0.0084 0.0724 0.1132
Loa Loa (eye worm) hypothetical protein 0.0023 0.0103 0.0168
Schistosoma mansoni tyrosine kinase 0.0155 0.145 0.1576
Loa Loa (eye worm) RGC/RGC protein kinase 0.0029 0.0159 0.0257
Echinococcus multilocularis Tubulin beta 2C chain 0.0026 0.0131 0.0131
Schistosoma mansoni voltage-gated potassium channel 0.0036 0.0234 0.0254
Schistosoma mansoni glutamate receptor AMPA 0.0167 0.1574 0.171
Loa Loa (eye worm) hypothetical protein 0.0135 0.1244 0.2018
Schistosoma mansoni sodium/chloride dependent neurotransmitter transporter 0.0042 0.0296 0.0322
Echinococcus multilocularis FAD linked sulfhydryl oxidase ALR 0.0035 0.0225 0.0225
Schistosoma mansoni hypothetical protein 0.0016 0.0029 0.0031
Treponema pallidum hypothetical protein 0.0024 0.0108 0.0149
Brugia malayi O-Glycosyl hydrolase family 30 protein 0.0266 0.2593 0.4205
Brugia malayi Cytochrome P450 family protein 0.002 0.0067 0.0109
Trypanosoma brucei NADPH:adrenodoxin oxidoreductase, mitochondrial, putative 0.0086 0.0743 0.0879
Echinococcus multilocularis thioredoxin glutathione reductase 0.0615 0.6166 0.6166
Onchocerca volvulus Atrial natriuretic peptide receptor 3 homolog 0.0029 0.0159 0.0354
Schistosoma mansoni transient receptor potential cation channel subfamily m member 0.0036 0.0234 0.0254
Schistosoma mansoni hypothetical protein 0.0422 0.4187 0.4549
Mycobacterium tuberculosis DNA gyrase (subunit A) GyrA (DNA topoisomerase (ATP-hydrolysing)) (DNA topoisomerase II) (type II DNA topoisomerase) 0.0031 0.018 0.0246
Trypanosoma brucei beta tubulin 0.0026 0.0131 0.0134
Trichomonas vaginalis CMGC family protein kinase 0.0053 0.0401 0.1221
Echinococcus granulosus g protein coupled receptor 0.0135 0.1244 0.1244
Loa Loa (eye worm) hypothetical protein 0.0036 0.0236 0.0383
Echinococcus granulosus tyrosine protein kinase Fyn 0.004 0.0269 0.0269
Echinococcus multilocularis fmrfamide receptor 0.0135 0.1244 0.1244
Schistosoma mansoni tyrosine kinase 0.005 0.0377 0.041
Toxoplasma gondii 4'-phosphopantetheinyl transferase superfamily protein 0.0024 0.011 0.0131
Loa Loa (eye worm) norepinephrine transporter 0.0249 0.2419 0.3923
Echinococcus granulosus Potassium voltage gated channel protein Shaw 0.0036 0.0234 0.0234
Echinococcus granulosus GPCR family 2 0.0016 0.0029 0.0029
Mycobacterium leprae PROBABLE NADH DEHYDROGENASE NDH 0.0193 0.1837 0.4197
Echinococcus granulosus microtubule associated protein 2 0.0711 0.7159 0.7159
Brugia malayi neuropeptide F receptor 0.0135 0.1244 0.2018
Plasmodium falciparum type II NADH:ubiquinone oxidoreductase 0.0086 0.0743 0.1162
Schistosoma mansoni hyperpolarization activated cyclic nucleotide-gated potassium channel 0.0041 0.0285 0.031
Echinococcus multilocularis beta tubulin 0.0026 0.0131 0.0131
Schistosoma mansoni voltage-gated potassium channel 0.0036 0.0234 0.0254
Loa Loa (eye worm) hypothetical protein 0.0135 0.1244 0.2018
Loa Loa (eye worm) hypothetical protein 0.002 0.0065 0.0106
Toxoplasma gondii transporter, cation channel family protein 0.0054 0.0421 0.0638
Brugia malayi Sodium:neurotransmitter symporter family protein 0.0249 0.2419 0.3923
Loa Loa (eye worm) hypothetical protein 0.044 0.4371 0.709
Giardia lamblia Glutamate synthase 0.0086 0.0743 0.2186
Loa Loa (eye worm) hypothetical protein 0.0021 0.0076 0.0123
Mycobacterium ulcerans cytochrome P450 185A4 Cyp185A4 0.002 0.0067 0.0019
Echinococcus multilocularis two pore calcium channel protein 2 0.0036 0.0234 0.0234
Leishmania major beta tubulin 0.0026 0.0131 0.0134
Mycobacterium ulcerans dihydrolipoamide dehydrogenase, LpdB 0.0323 0.3179 1
Toxoplasma gondii CMGC kinase, MAPK family (ERK) MAPK-1 0.0053 0.0401 0.0606
Schistosoma mansoni voltage-gated potassium channel 0.0036 0.0234 0.0254
Echinococcus granulosus Glutamate receptor ionotropic kainate 2 0.019 0.1815 0.1815
Echinococcus granulosus tachykinin peptides receptor 99D 0.0135 0.1244 0.1244
Echinococcus multilocularis voltage gated hydrogen channel 1 0.0036 0.0234 0.0234
Loa Loa (eye worm) hypothetical protein 0.0052 0.0391 0.0634
Trichomonas vaginalis glucosylceramidase, putative 0.0266 0.2593 0.8149
Echinococcus multilocularis potassium voltage gated channel subfamily H 0.0072 0.0598 0.0598
Toxoplasma gondii DNA topoisomerase 2, putative 0.0144 0.134 0.2136
Entamoeba histolytica pyridine nucleotide-disulfide oxidoreductase family protein 0.0086 0.0743 0.2357
Onchocerca volvulus 0.0041 0.0279 0.087
Echinococcus granulosus glutamate receptor 2 0.019 0.1815 0.1815
Schistosoma mansoni ap endonuclease 0.0019 0.0061 0.0066
Schistosoma mansoni lamin 0.0028 0.0148 0.016
Brugia malayi PHD-finger family protein 0.003 0.0171 0.0276
Brugia malayi Intermediate filament tail domain containing protein 0.0028 0.0148 0.0239
Entamoeba histolytica fructose-1,6-bisphosphate aldolase, putative 0.0301 0.2953 1
Trypanosoma cruzi PAB1-binding protein , putative 0.0026 0.0129 0.0131
Leishmania major target of rapamycin kinase (TOR) kinase 3 0.0037 0.0241 0.0267
Brugia malayi exodeoxyribonuclease III family protein 0.0019 0.0061 0.0099
Trypanosoma cruzi DNA topoisomerase II, putative 0.0136 0.1261 0.1511
Schistosoma mansoni sodium-dependent neurotransmitter transporter 0.0042 0.0296 0.0322
Echinococcus multilocularis g protein coupled receptor 0.0135 0.1244 0.1244
Echinococcus multilocularis rhodopsin orphan GPCR 0.0135 0.1244 0.1244
Loa Loa (eye worm) hypothetical protein 0.0025 0.0121 0.0197
Schistosoma mansoni sulfide quinone reductase 0.0086 0.0743 0.0807
Brugia malayi glutathione reductase 0.0615 0.6166 1
Brugia malayi Adenylyl cyclase protein 0.008 0.0686 0.1113
Echinococcus multilocularis tubulin subunit beta 0.0026 0.0131 0.0131
Treponema pallidum hypothetical protein 0.0029 0.016 0.0317
Trichomonas vaginalis glucosylceramidase, putative 0.0175 0.1654 0.5181
Echinococcus granulosus g protein linked acetylcholine receptor gar 2a 0.0135 0.1244 0.1244
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0018 0.0052 0.0117
Mycobacterium ulcerans carbon monoxide dehydrogenase 0.0118 0.1076 0.3255
Plasmodium vivax NAD(P)H-dependent glutamate synthase, putative 0.0086 0.0743 0.1162
Mycobacterium ulcerans glutamate synthase subunit beta 0.0086 0.0743 0.2186
Schistosoma mansoni biogenic amine receptor 0.0135 0.1244 0.1352
Leishmania major acetoin dehydrogenase e3 component-like protein 0.0634 0.6369 0.7742
Loa Loa (eye worm) hypothetical protein 0.0036 0.0234 0.0379
Schistosoma mansoni sodium-dependent amino acid transporter 0.0042 0.0296 0.0322
Trichomonas vaginalis PIKK family atypical protein kinase 0.0025 0.0119 0.0328
Trypanosoma cruzi calmodulin 0.0025 0.0121 0.0121
Loa Loa (eye worm) voltage-gated potassium channel 0.0036 0.0234 0.0379
Echinococcus multilocularis tyrosine protein kinase Fyn 0.004 0.0269 0.0269
Schistosoma mansoni biogenic amine (5HT) receptor 0.0386 0.382 0.415
Echinococcus multilocularis calcium activated potassium channel 0.0037 0.0239 0.0239
Trypanosoma cruzi mitogen-activated protein kinase 11, putative 0.0053 0.0401 0.0463
Mycobacterium ulcerans dehydrogenase 0.0086 0.0743 0.2186
Loa Loa (eye worm) inositol-1 0.0038 0.0253 0.041
Wolbachia endosymbiont of Brugia malayi DNA gyrase, topoisomerase II, B subunit, GyrB 0.0084 0.0724 0.2127
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0301 0.2953 0.9285
Trypanosoma brucei target of rapamycin kinase 3, putative 0.0037 0.0241 0.0267
Trypanosoma cruzi hypothetical protein, conserved 0.0086 0.0743 0.0879
Trichomonas vaginalis conserved hypothetical protein 0.0029 0.0155 0.0442
Echinococcus multilocularis allatostatin A receptor 0.0135 0.1244 0.1244
Onchocerca volvulus 0.0135 0.1244 0.4987
Echinococcus multilocularis neuropeptide FF receptor 2 0.0135 0.1244 0.1244
Echinococcus multilocularis tyrosine protein kinase Fgr 0.004 0.0269 0.0269
Loa Loa (eye worm) hypothetical protein 0.0098 0.0863 0.1399
Echinococcus multilocularis tyrosine protein kinase Blk 0.0036 0.0231 0.0231
Echinococcus granulosus jumonji domain containing protein 0.0042 0.0291 0.0291
Echinococcus multilocularis potassium voltage gated channel subfamily KQT 0.0036 0.0234 0.0234
Echinococcus granulosus tubulin beta 4A class IVa 0.0026 0.0131 0.0131
Schistosoma mansoni hypothetical protein 0.0135 0.1244 0.1352
Echinococcus granulosus rhodopsin orphan GPCR 0.0135 0.1244 0.1244
Onchocerca volvulus 0.0135 0.1244 0.4987
Loa Loa (eye worm) nuclear hormone receptor family member nhr-14 0.0021 0.0076 0.0123
Brugia malayi isocitrate dehydrogenase 0.0016 0.0029 0.0047
Echinococcus multilocularis tyrosine protein kinase Fyn 0.004 0.0269 0.0269
Echinococcus granulosus sodium and chloride dependent glycine 0.0042 0.0296 0.0296
Trichomonas vaginalis PIKK family atypical protein kinase 0.0028 0.0146 0.0416
Plasmodium vivax calmodulin, putative 0.0025 0.0121 0.015
Brugia malayi Unidentified vitellogenin-linked transcript protein 6, putative 0.0135 0.1244 0.2018
Loa Loa (eye worm) RGC/RGC protein kinase 0.0029 0.0159 0.0257
Onchocerca volvulus 0.005 0.0372 0.1267
Onchocerca volvulus 0.0135 0.1244 0.4987
Echinococcus multilocularis g protein linked acetylcholine receptor gar 2a 0.0135 0.1244 0.1244
Trypanosoma cruzi calmodulin, putative 0.0025 0.0121 0.0121
Leishmania major dihydrolipoamide dehydrogenase, putative 0.0815 0.8221 1
Echinococcus granulosus FTZ F1 nuclear receptor protein 0.0021 0.0076 0.0076
Entamoeba histolytica thioredoxin reductase, putative 0.0086 0.0743 0.2357
Schistosoma mansoni glutamate receptor NMDA 0.0338 0.3326 0.3613
Echinococcus multilocularis rhodopsin orphan GPCR 0.0135 0.1244 0.1244
Echinococcus granulosus orexin receptor type 2 0.0135 0.1244 0.1244
Schistosoma mansoni muscarinic acetylcholine (GAR) receptor 0.0135 0.1244 0.1352
Loa Loa (eye worm) phosphatidylinositol 3 0.0046 0.0338 0.0547
Toxoplasma gondii LsmAD domain-containing protein 0.0026 0.0129 0.0162
Schistosoma mansoni dihydrolipoamide dehydrogenase 0.0323 0.3179 0.3453
Echinococcus granulosus glutamate receptor ionotrophic AMPA 3 0.019 0.1815 0.1815
Echinococcus multilocularis chromobox protein 1 0.0072 0.0599 0.0599
Brugia malayi MAP kinase sur-1 0.0053 0.0401 0.065
Mycobacterium leprae Probable DNA gyrase (subunit B) GyrB (DNA topoisomerase (ATP-hydrolysing)) (DNA topoisomerase II) (Type II DNA topoisomerase) 0.0037 0.0246 0.0407
Toxoplasma gondii endonuclease IV APN 0.0079 0.0673 0.1048
Loa Loa (eye worm) hypothetical protein 0.0036 0.0234 0.0379
Echinococcus granulosus 3'partial|tyrosine protein kinase Fgr 0.004 0.0269 0.0269
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.0036 0.0234 0.0333
Brugia malayi cytoplasmic intermediate filament protein 0.0015 0.0015 0.0024
Echinococcus multilocularis transient receptor potential cation channel 0.0036 0.0234 0.0234
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0021 0.0076 0.0123
Trypanosoma brucei hypothetical protein, conserved 0.0086 0.0743 0.0879
Brugia malayi gonadotropin-releasing hormone receptor 2 0.0135 0.1244 0.2018
Schistosoma mansoni peptide (FMRFamide/somatostatin)-like receptor 0.0135 0.1244 0.1352
Brugia malayi Nuclear hormone receptor family member nhr-3 0.0021 0.0076 0.0123
Leishmania major trypanothione reductase 0.0615 0.6166 0.7493
Mycobacterium tuberculosis Possible dehydrogenase/reductase 0.0086 0.0743 0.1162
Echinococcus multilocularis ryanodine receptor 44f 0.0036 0.0234 0.0234
Echinococcus multilocularis voltage dependent calcium channel type d subunit 0.0133 0.1224 0.1224
Entamoeba histolytica protein kinase, putative 0.0032 0.0191 0.0448
Echinococcus multilocularis histone lysine methyltransferase setb histone lysine methyltransferase eggless 0.0031 0.0185 0.0185
Loa Loa (eye worm) hypothetical protein 0.0135 0.1244 0.2018
Schistosoma mansoni sodium-dependent neurotransmitter transporter 0.0042 0.0296 0.0322
Toxoplasma gondii transporter, cation channel family protein 0.0036 0.0234 0.0333
Schistosoma mansoni ataxia telangiectasia mutated (atm)-related 0.0046 0.0338 0.0366
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0031 0.0185 0.02
Schistosoma mansoni tyrosyl-DNA phosphodiesterase 0.0068 0.056 0.0609
Toxoplasma gondii calmodulin, putative 0.0025 0.0121 0.015
Schistosoma mansoni inositol 145-trisphosphate receptor 0.0036 0.0234 0.0254
Toxoplasma gondii target of rapamycin (TOR), putative 0.0034 0.0216 0.0304
Echinococcus granulosus thyrotropin releasing hormone receptor 0.0135 0.1244 0.1244
Onchocerca volvulus 0.0135 0.1244 0.4987
Toxoplasma gondii beta-1 tubulin, putative 0.0026 0.0131 0.0166
Trichomonas vaginalis PIKK family atypical protein kinase 0.0016 0.0022 0.0022
Onchocerca volvulus Alhambra homolog 0.003 0.0171 0.0406
Brugia malayi Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain containing protein 0.0238 0.2299 0.3728
Echinococcus granulosus RUN 0.0041 0.0279 0.0279
Echinococcus granulosus Tubulin beta 2C chain 0.0026 0.0131 0.0131
Trypanosoma cruzi isocitrate dehydrogenase [NADP], mitochondrial precursor, putative 0.0016 0.0029 0.0009
Echinococcus multilocularis g protein coupled receptor 0.0135 0.1244 0.1244
Giardia lamblia Beta tubulin 0.0026 0.0131 0.0225
Echinococcus multilocularis glutamate receptor, ionotrophic, AMPA 3 0.019 0.1815 0.1815
Echinococcus multilocularis g protein coupled receptor 0.0135 0.1244 0.1244
Loa Loa (eye worm) glutathione reductase 0.0615 0.6166 1
Treponema pallidum amino acid ABC transporter, periplasmic binding protein 0.0039 0.0262 0.0644
Mycobacterium tuberculosis DNA gyrase (subunit B) GyrB (DNA topoisomerase (ATP-hydrolysing)) (DNA topoisomerase II) (type II DNA topoisomerase) 0.0084 0.0724 0.1132
Giardia lamblia Glycerol-3-phosphate dehydrogenase 0.0086 0.0743 0.2186
Echinococcus multilocularis lipoxygenase domain containing protein 0.0041 0.0279 0.0279
Schistosoma mansoni vesicular amine transporter 0.0036 0.0234 0.0254
Brugia malayi sulfakinin receptor protein 0.0135 0.1244 0.2018
Echinococcus multilocularis nmda type glutamate receptor 0.0192 0.1828 0.1828
Schistosoma mansoni glutamate receptor NMDA 0.0272 0.2649 0.2878
Echinococcus multilocularis dihydropyrimidine dehydrogenase (NADP+) 0.0086 0.0743 0.0743
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0301 0.2953 0.9285
Trypanosoma cruzi myo-inositol-1(or 4)-monophosphatase 1, putative 0.0038 0.0253 0.0282
Onchocerca volvulus Putative DNA topoisomerase 2, mitochondrial 0.0097 0.0861 0.3352
Brugia malayi G-protein coupled receptor 0.0135 0.1244 0.2018
Echinococcus granulosus Transcription factor JmjC domain containing protein 0.0098 0.0872 0.0872
Trypanosoma brucei FAT domain/Rapamycin binding domain/Phosphatidylinositol 3- and 4-kinase, putative 0.0019 0.006 0.0046
Trypanosoma cruzi trypanothione reductase, putative 0.0615 0.6166 0.7493
Echinococcus granulosus lysine specific demethylase 5A 0.0038 0.0253 0.0253
Trypanosoma cruzi mitochondrial DNA topoisomerase II, putative 0.0162 0.1521 0.1829
Brugia malayi Hypothetical 29.7 kDa protein C05D11.5 in chromosome III 0.0021 0.0076 0.0122
Schistosoma mansoni peptide (FMRFamide/neurokinin-3)-like receptor 0.0135 0.1244 0.1352
Loa Loa (eye worm) hypothetical protein 0.0023 0.0103 0.0168
Onchocerca volvulus 0.0032 0.0186 0.0472
Trypanosoma cruzi cytochrome P450, putative 0.002 0.0067 0.0056
Echinococcus multilocularis sodium:chloride dependent neurotransmitter 0.0042 0.0296 0.0296
Schistosoma mansoni high voltage-activated calcium channel Cav1 0.0133 0.1224 0.133
Echinococcus granulosus tyrosine protein kinase HCK 0.0032 0.0191 0.0191
Brugia malayi AKH receptor 0.0135 0.1244 0.2018
Brugia malayi RE15519p 0.0135 0.1244 0.2018
Echinococcus granulosus diuretic hormone 44 receptor GPRdih2 0.0016 0.0029 0.0029
Toxoplasma gondii hypothetical protein 0.0018 0.0049 0.0033
Loa Loa (eye worm) nuclear Hormone Receptor family member 0.0021 0.0076 0.0123
Loa Loa (eye worm) hypothetical protein 0.0562 0.5622 0.9119
Echinococcus granulosus Glutamate receptor ionotropic kainate 2 0.019 0.1815 0.1815
Echinococcus multilocularis geminin 0.0175 0.1654 0.1654
Loa Loa (eye worm) hypothetical protein 0.0084 0.0726 0.1177
Schistosoma mansoni voltage-gated potassium channel 0.0036 0.0234 0.0254
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0021 0.0076 0.0076
Trichomonas vaginalis PIKK family atypical protein kinase 0.0027 0.0144 0.0407
Schistosoma mansoni biogenic amine (octopamine/dopamine) receptor 0.044 0.4371 0.4749
Trichomonas vaginalis PIKK family atypical protein kinase 0.0037 0.024 0.0713
Schistosoma mansoni opsin-like receptor 0.0135 0.1244 0.1352
Brugia malayi Latrophilin receptor protein 2 0.0016 0.0029 0.0047
Echinococcus granulosus nmda type glutamate receptor 0.0192 0.1828 0.1828
Echinococcus granulosus cadherin EGF LAG seven pass G type receptor 0.0016 0.0029 0.0029
Onchocerca volvulus 0.0051 0.0385 0.1322
Echinococcus multilocularis potassium voltage gated channel protein 0.0036 0.0234 0.0234
Loa Loa (eye worm) hypothetical protein 0.0135 0.1244 0.2018
Echinococcus granulosus hepatocyte nuclear factor 4 alpha 0.0021 0.0076 0.0076
Echinococcus granulosus cpg binding protein 0.0031 0.0183 0.0183
Brugia malayi metabotropic GABA-B receptor subtype 2 0.0023 0.0103 0.0167
Schistosoma mansoni glutamate receptor kainate 0.0167 0.1574 0.171
Plasmodium vivax thioredoxin reductase, putative 0.0615 0.6166 1
Echinococcus multilocularis Glutamate receptor, ionotropic kainate 2 0.019 0.1815 0.1815
Trypanosoma cruzi Present in the outer mitochondrial membrane proteome 4 0.0035 0.0225 0.0248
Echinococcus granulosus dnaJ subfamily B 0.0422 0.4187 0.4187
Trypanosoma brucei calmodulin 0.0025 0.0121 0.0121
Trypanosoma brucei beta tubulin 0.0026 0.0131 0.0134
Onchocerca volvulus Heterochromatin protein 1 homolog 0.0043 0.0307 0.0986
Loa Loa (eye worm) hypothetical protein 0.0021 0.0076 0.0123
Echinococcus granulosus potassium voltage gated channel subfamily C 0.0036 0.0234 0.0234
Echinococcus granulosus cyclic nucleotide gated cation channel alpha 3 0.0041 0.0285 0.0285
Trypanosoma brucei calmodulin 0.0025 0.0121 0.0121
Echinococcus granulosus NADPH:adrenodoxin oxidoreductase 0.0086 0.0743 0.0743
Echinococcus multilocularis potassium voltage gated channel subfamily D 0.0036 0.0234 0.0234
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0301 0.2953 0.9285
Loa Loa (eye worm) hypothetical protein 0.0133 0.1224 0.1985
Echinococcus multilocularis tyrosine kinase 0.0025 0.0123 0.0123
Loa Loa (eye worm) hypothetical protein 0.0059 0.0464 0.0752
Echinococcus granulosus beta tubulin 0.0026 0.0131 0.0131
Plasmodium vivax hypothetical protein, conserved 0.0042 0.0296 0.0435
Schistosoma mansoni cpg binding protein 0.003 0.0166 0.018
Echinococcus granulosus short transient receptor potential channel 6 0.0036 0.0236 0.0236
Echinococcus multilocularis tyrosine protein kinase Srms 0.0036 0.0231 0.0231
Trypanosoma cruzi dihydrolipoyl dehydrogenase, putative 0.0323 0.3179 0.385
Echinococcus multilocularis transcription factor Dp 1 0.0039 0.0266 0.0266
Brugia malayi DNA topoisomerase II, alpha isozyme 0.0144 0.134 0.2173
Schistosoma mansoni voltage-gated potassium channel 0.0075 0.0634 0.0688
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0021 0.0076 0.0076
Treponema pallidum fructose-bisphosphate aldolase 0.0301 0.2953 0.9275
Loa Loa (eye worm) hypothetical protein 0.0021 0.0076 0.0123
Schistosoma mansoni nuclear receptor 2DBD-gamma 0.0021 0.0076 0.0082
Echinococcus multilocularis isocitrate dehydrogenase 0.0016 0.0029 0.0029
Schistosoma mansoni coup transcription factor 0.0021 0.0076 0.0082
Mycobacterium tuberculosis Probable NADPH:adrenodoxin oxidoreductase FprB (adrenodoxin reductase) (AR) (ferredoxin-NADP(+) reductase) 0.0086 0.0743 0.1162
Plasmodium falciparum thioredoxin reductase 0.0323 0.3179 0.5132
Echinococcus granulosus tumor protein p63 0.0348 0.3435 0.3435
Echinococcus granulosus 7TM GPCR rhodopsin 0.0135 0.1244 0.1244
Loa Loa (eye worm) hypothetical protein 0.0135 0.1244 0.2018
Entamoeba histolytica disulphide oxidoreductase, putative 0.0086 0.0743 0.2357
Echinococcus granulosus TRP transient receptor potential channel 0.0036 0.0234 0.0234
Loa Loa (eye worm) PHD-finger family protein 0.003 0.0171 0.0277
Schistosoma mansoni glutamate synthase 0.0086 0.0743 0.0807
Echinococcus granulosus neuropeptide receptor 0.0135 0.1244 0.1244
Toxoplasma gondii histone lysine methyltransferase SET1 0.0057 0.0449 0.0684
Loa Loa (eye worm) hypothetical protein 0.0036 0.0234 0.0379
Brugia malayi G protein-coupled receptor F59B2.13 0.0135 0.1244 0.2018
Echinococcus multilocularis FTZ F1 alpha 0.0021 0.0076 0.0076
Plasmodium vivax DNA topoisomerase II, putative 0.0144 0.134 0.2136
Brugia malayi DNA-(Apurinic or apyrimidinic site) lyase 0.0079 0.0673 0.1091
Mycobacterium ulcerans NADPH:adrenodoxin oxidoreductase FprA 0.0086 0.0743 0.2186
Loa Loa (eye worm) hypothetical protein 0.002 0.0065 0.0106
Plasmodium vivax ataxin-2 like protein, putative 0.0026 0.0129 0.0162
Mycobacterium tuberculosis Probable nitrite reductase [NAD(P)H] large subunit [FAD flavoprotein] NirB 0.0193 0.1837 0.2946
Echinococcus granulosus lamin 0.0028 0.0148 0.0148
Echinococcus granulosus transient receptor potential cation channel 0.0036 0.0234 0.0234
Schistosoma mansoni voltage-gated cation channel 0.0133 0.1224 0.133
Brugia malayi Sodium:neurotransmitter symporter family protein 0.0042 0.0296 0.048
Echinococcus granulosus tubulin subunit beta 0.0026 0.0131 0.0131
Onchocerca volvulus Steroid hormone receptor family member cnr14 homolog 0.0021 0.0076 0.0003
Brugia malayi hypothetical protein 0.0017 0.0034 0.0055
Echinococcus granulosus voltage dependent L type calcium channel subunit|voltage dependent calcium channel 0.0133 0.1224 0.1224
Schistosoma mansoni voltage-gated potassium channel 0.0045 0.0321 0.0348
Echinococcus granulosus Glutamate receptor ionotropic kainate 2 0.019 0.1815 0.1815
Leishmania major beta tubulin 0.0026 0.0131 0.0134
Echinococcus granulosus L aminoadipate semialdehyde 0.0086 0.0741 0.0741
Echinococcus multilocularis sulfide:quinone oxidoreductase 0.0086 0.0743 0.0743
Echinococcus granulosus g protein coupled receptor 0.0135 0.1244 0.1244
Loa Loa (eye worm) hypothetical protein 0.0041 0.0279 0.0453
Schistosoma mansoni histamine h1 receptor 0.0135 0.1244 0.1352
Brugia malayi Sodium:neurotransmitter symporter family protein 0.0042 0.0296 0.048
Loa Loa (eye worm) hypothetical protein 0.0135 0.1244 0.2018
Loa Loa (eye worm) hypothetical protein 0.0042 0.0296 0.0481
Brugia malayi Voltage-gated potassium channel, Shaw-family (KCNC, Kv3-like) alpha-subunit 0.0036 0.0234 0.0378
Wolbachia endosymbiont of Brugia malayi thioredoxin reductase 0.0086 0.0743 0.2186
Brugia malayi DNA gyrase/topoisomerase IV, A subunit family protein 0.0144 0.134 0.2173
Trypanosoma cruzi C-8 sterol isomerase, putative 0.038 0.3756 0.4554
Leishmania major cytochrome p450-like protein 0.002 0.0067 0.0056
Schistosoma mansoni voltage-gated potassium channel 0.0036 0.0234 0.0254
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0135 0.1244 0.1352
Echinococcus multilocularis rhodopsin orphan GPCR 0.0135 0.1244 0.1244
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0018 0.0052 0.0117
Echinococcus multilocularis voltage dependent L type calcium channel subunit 0.0133 0.1224 0.1224
Schistosoma mansoni hypothetical protein 0.0036 0.0234 0.0254
Giardia lamblia GTOR 0.0046 0.0338 0.0886
Brugia malayi Large-conductance calcium-activated potassium channel Slo-1 (KCNMA) alpha subunit. C. elegans slo-1 ortholog 0.0036 0.0234 0.0378
Plasmodium falciparum FAD-linked sulfhydryl oxidase ERV1, putative 0.0035 0.0225 0.0319
Leishmania major C-8 sterol isomerase-like protein 0.038 0.3756 0.4554
Loa Loa (eye worm) hypothetical protein 0.0249 0.2419 0.3923
Echinococcus multilocularis growth hormone secretagogue receptor type 1 0.0135 0.1244 0.1244
Echinococcus granulosus potassium voltage gated channel subfamily D 0.0036 0.0234 0.0234
Loa Loa (eye worm) hypothetical protein 0.0042 0.0296 0.0481
Mycobacterium ulcerans NADH dehydrogenase 0.0086 0.0743 0.2186
Trypanosoma cruzi calmodulin, putative 0.0025 0.0121 0.0121
Brugia malayi Calcitonin receptor-like protein seb-1 0.0051 0.0389 0.0631
Toxoplasma gondii DNA gyrase/topoisomerase IV, A subunit domain-containing protein 0.0031 0.018 0.0246
Schistosoma mansoni biogenic amine (5HT) receptor 0.0911 0.9204 1
Loa Loa (eye worm) hypothetical protein 0.0135 0.1244 0.2018
Trypanosoma cruzi target of rapamycin kinase 3 0.0037 0.0241 0.0267
Brugia malayi bZIP transcription factor family protein 0.0087 0.075 0.1217
Loa Loa (eye worm) hypothetical protein 0.0135 0.1244 0.2018
Echinococcus granulosus CalModulin family member cmd 1 0.0025 0.0121 0.0121
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0135 0.1244 0.1352
Toxoplasma gondii Sodium:neurotransmitter symporter family protein 0.0042 0.0296 0.0435
Schistosoma mansoni tyrosine kinase 0.0082 0.0701 0.0761
Brugia malayi Blistered cuticle protein 3 0.0075 0.0631 0.1022
Schistosoma mansoni rab6-interacting 0.0041 0.0279 0.0303
Echinococcus granulosus voltage dependent calcium channel 0.0133 0.1224 0.1224
Mycobacterium ulcerans epimerase 0.0021 0.0076 0.0046
Onchocerca volvulus 0.0135 0.1244 0.4987
Toxoplasma gondii histone lysine methyltransferase SET/SUV39 0.0031 0.0185 0.0253
Trichomonas vaginalis disulfide oxidoreductase, putative 0.0086 0.0743 0.23
Loa Loa (eye worm) steroid hormone receptor 0.0021 0.0076 0.0123
Mycobacterium leprae Probable fructose bisphosphate aldolase Fba 0.0147 0.1372 0.3089
Echinococcus granulosus FAD linked sulfhydryl oxidase ALR 0.0035 0.0225 0.0225
Loa Loa (eye worm) hypothetical protein 0.0035 0.0223 0.0361
Schistosoma mansoni voltage-gated ion channel 0.0036 0.0234 0.0254
Trichomonas vaginalis voltage and ligand gated potassium channel, putative 0.0017 0.0036 0.0065
Trichomonas vaginalis chromobox protein, putative 0.0043 0.0307 0.0922
Echinococcus multilocularis tyrosine protein kinase lyn lyn a protein tyrosine kinase lymphocyte specific protein tyrosine kinase 0.004 0.0269 0.0269
Echinococcus granulosus potassium voltage gated channel subfamily H 0.0045 0.0321 0.0321
Schistosoma mansoni hypothetical protein 0.0041 0.0279 0.0303
Schistosoma mansoni tubulin subunit beta 0.0026 0.0131 0.0142
Trichomonas vaginalis PIKK family atypical protein kinase 0.0037 0.024 0.0713
Echinococcus multilocularis NADP dependent isocitrate dehydrogenase 0.0016 0.0029 0.0029
Schistosoma mansoni two-pore calcium channel 0.0036 0.0234 0.0254
Echinococcus granulosus chromobox protein 1 0.0072 0.0599 0.0599
Trichomonas vaginalis conserved hypothetical protein 0.0015 0.002 0.0016
Trichomonas vaginalis PIKK family atypical protein kinase 0.0031 0.0181 0.0526
Loa Loa (eye worm) O-glycosyl hydrolase family 30 protein 0.0266 0.2593 0.4206
Schistosoma mansoni jumonji/arid domain-containing protein 0.0038 0.0253 0.0274
Brugia malayi larval opioid receptor 0.0135 0.1244 0.2018
Brugia malayi Augmenter of liver regeneration 0.0035 0.0225 0.0365
Leishmania major beta tubulin 0.0026 0.0131 0.0134
Echinococcus multilocularis transient receptor potential cation channel 0.0036 0.0236 0.0236
Echinococcus multilocularis PHD finger protein rhinoceros 0.003 0.0171 0.0171
Loa Loa (eye worm) adenylyl cyclase 3 0.008 0.0686 0.1113
Plasmodium falciparum ferrodoxin reductase-like protein 0.0086 0.0743 0.1162
Schistosoma mansoni histamine-responsive GPCR (AAF21638) 0.0135 0.1244 0.1352
Loa Loa (eye worm) hypothetical protein 0.0036 0.0234 0.0379
Trypanosoma brucei inositol-1(or 4)-monophosphatase 1, putative 0.0038 0.0253 0.0282
Schistosoma mansoni neuropeptide F-like receptor 0.0135 0.1244 0.1352
Mycobacterium ulcerans endonuclease IV 0.0079 0.0673 0.1962
Brugia malayi hypothetical protein 0.0026 0.0129 0.0209
Toxoplasma gondii Erv1 / Alr family protein 0.0035 0.0225 0.0319
Onchocerca volvulus Glucosylceramidase homolog 0.0175 0.1654 0.6736
Echinococcus granulosus calmodulin 0.0025 0.0121 0.0121
Schistosoma mansoni tubulin subunit beta 0.0026 0.0131 0.0142
Schistosoma mansoni alpha-1 adrenergic receptor 0.0135 0.1244 0.1352
Brugia malayi hypothetical protein 0.0036 0.0234 0.0378
Schistosoma mansoni cyclic-nucleotide-gated cation channel 0.0041 0.0285 0.031
Echinococcus granulosus short transient receptor potential channel 6 0.0036 0.0234 0.0234
Entamoeba histolytica calmodulin, putative 0.0025 0.0121 0.0208
Echinococcus multilocularis voltage gated potassium channel 0.0036 0.0234 0.0234
Loa Loa (eye worm) cyclic-nucleotide gated cation channel 0.0041 0.0285 0.0462
Echinococcus multilocularis DNA (apurinic or apyrimidinic site) lyase 0.0019 0.0061 0.0061
Trichomonas vaginalis glucosylceramidase, putative 0.0266 0.2593 0.8149
Echinococcus granulosus tyrosine protein kinase Src42A 0.004 0.0269 0.0269
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0135 0.1244 0.1352
Echinococcus multilocularis apoptosis inducing factor 1 mitochondrial 0.0086 0.0743 0.0743
Wolbachia endosymbiont of Brugia malayi thioredoxin reductase 0.0086 0.0743 0.2186
Echinococcus granulosus sulfide:quinone oxidoreductase 0.0086 0.0743 0.0743
Echinococcus multilocularis potassium large conductance calcium activated 0.0036 0.0234 0.0234
Loa Loa (eye worm) hypothetical protein 0.0135 0.1244 0.2018
Echinococcus granulosus G protein coupled 5 hydroxytryptamine receptor 0.0135 0.1244 0.1244
Loa Loa (eye worm) BEN-1 protein 0.0026 0.0131 0.0213
Toxoplasma gondii selenide, water dikinase 0.0086 0.0743 0.1162
Brugia malayi Protein kinase domain containing protein 0.005 0.0377 0.0612
Loa Loa (eye worm) voltage-gated potassium channel 0.0036 0.0234 0.0379
Onchocerca volvulus 0.0135 0.1244 0.4987
Trichomonas vaginalis conserved hypothetical protein 0.004 0.0275 0.0823
Echinococcus granulosus apoptosis inducing factor 1 mitochondrial 0.0086 0.0743 0.0743
Brugia malayi Nuclear hormone receptor family member nhr-1 0.0021 0.0076 0.0123
Brugia malayi intermediate filament protein 0.0028 0.0148 0.0239
Trypanosoma cruzi hypothetical protein, conserved 0.0086 0.0743 0.0879
Echinococcus multilocularis musashi 0.0028 0.0148 0.0148
Schistosoma mansoni neuropeptide receptor 0.0135 0.1244 0.1352
Trichomonas vaginalis ap endonuclease, putative 0.0019 0.0061 0.0147
Trichomonas vaginalis PIKK family atypical protein kinase 0.0037 0.024 0.0713
Echinococcus multilocularis G protein coupled 5 hydroxytryptamine receptor 0.0135 0.1244 0.1244
Loa Loa (eye worm) hypothetical protein 0.0135 0.1244 0.2018
Leishmania major hypothetical protein, unknown function 0.0036 0.0234 0.0258
Brugia malayi Sodium:neurotransmitter symporter family protein 1, putative 0.0042 0.0296 0.048
Mycobacterium tuberculosis Probable carbon monoxyde dehydrogenase (large chain) 0.0084 0.0726 0.1135
Echinococcus granulosus transient receptor potential cation channel 0.0036 0.0234 0.0234
Treponema pallidum thioredoxin reductase (trxB) 0.0086 0.0743 0.2186
Echinococcus multilocularis peregrin 0.003 0.0171 0.0171
Echinococcus granulosus intermediate filament protein 0.0028 0.0148 0.0148
Echinococcus multilocularis glutamate (NMDA) receptor subunit 0.0338 0.3326 0.3326
Loa Loa (eye worm) hypothetical protein 0.0244 0.2363 0.3832
Trypanosoma cruzi extracellular receptor, putative 0.0023 0.0103 0.01
Treponema pallidum quinoline 2-oxidoreductase 0.0028 0.0153 0.0295
Echinococcus multilocularis dnaJ subfamily B 0.0422 0.4187 0.4187
Entamoeba histolytica tyrosyl-DNA phosphodiesterase, putative 0.0068 0.056 0.1726
Plasmodium falciparum amino acid transporter, putative 0.0042 0.0296 0.0435
Mycobacterium tuberculosis Dihydrolipoamide dehydrogenase LpdC (lipoamide reductase (NADH)) (lipoyl dehydrogenase) (dihydrolipoyl dehydrogenase) (diaphoras 0.043 0.4273 0.6916
Schistosoma mansoni DNA topoisomerase II 0.0144 0.134 0.1456
Onchocerca volvulus 0.0135 0.1244 0.4987
Mycobacterium tuberculosis Probable thioredoxin reductase TrxB2 (TRXR) (TR) 0.0086 0.0743 0.1162
Toxoplasma gondii Erv1 / Alr family protein 0.0035 0.0225 0.0319
Echinococcus multilocularis thyroid hormone receptor alpha 0.0021 0.0076 0.0076
Echinococcus multilocularis alpha 1A adrenergic receptor 0.0135 0.1244 0.1244
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0018 0.0052 0.0117
Trypanosoma cruzi NADPH:adrenodoxin oxidoreductase, mitochondrial, putative 0.0086 0.0743 0.0879
Onchocerca volvulus 0.0021 0.0076 0.0003
Echinococcus multilocularis Transcription factor, JmjC domain containing protein 0.0098 0.0872 0.0872
Trichomonas vaginalis conserved hypothetical protein 0.004 0.0275 0.0823
Loa Loa (eye worm) hypothetical protein 0.0135 0.1244 0.2018
Leishmania major mitogen activated protein kinase 4, putative;with=GeneDB:LmxM19.1440 0.0053 0.0401 0.0463
Leishmania major phosphopantetheinyl transferase-like protein 0.0024 0.011 0.0107
Schistosoma mansoni neuropeptide f receptor 76f 0.0135 0.1244 0.1352
Echinococcus multilocularis thyrotropin releasing hormone receptor 0.0135 0.1244 0.1244
Echinococcus multilocularis glutamate synthase 0.0086 0.0743 0.0743
Loa Loa (eye worm) tyrosyl-DNA phosphodiesterase 0.0068 0.056 0.0909
Brugia malayi Voltage-gated calcium channel, L-type, alpha subunit. C. elegans egl-19 ortholog 0.0133 0.1224 0.1985
Brugia malayi Phosphatidylinositol 3- and 4-kinase family protein 0.0046 0.0338 0.0547
Mycobacterium leprae PROBABLE ENDONUCLEASE IV END (ENDODEOXYRIBONUCLEASE IV) (APURINASE) 0.0079 0.0673 0.1423
Schistosoma mansoni chromobox protein 0.0072 0.0599 0.0651
Trichomonas vaginalis voltage and ligand gated potassium channel, putative 0.0041 0.0285 0.0854
Echinococcus granulosus potassium voltage gated channel protein 0.0036 0.0234 0.0234
Toxoplasma gondii pyridine nucleotide-disulfide oxidoreductase domain-containing protein 0.0086 0.0743 0.1162
Loa Loa (eye worm) hypothetical protein 0.0135 0.1244 0.2018
Plasmodium falciparum calmodulin 0.0025 0.0121 0.015
Plasmodium falciparum tubulin beta chain 0.0026 0.0131 0.0166
Trichomonas vaginalis myo inositol monophosphatase, putative 0.0038 0.0253 0.0752
Loa Loa (eye worm) hypothetical protein 0.0021 0.0076 0.0123
Plasmodium falciparum transporter, putative 0.0042 0.0296 0.0435
Loa Loa (eye worm) neuropeptide F receptor 0.0135 0.1244 0.2018
Loa Loa (eye worm) hypothetical protein 0.0042 0.0296 0.0481
Echinococcus multilocularis glutamate receptor subunit protein glur 0.0071 0.0594 0.0594
Brugia malayi voltage-dependent calcium channel 0.0036 0.0234 0.0378
Echinococcus multilocularis adenylate cyclase 9 0.008 0.0686 0.0686
Wolbachia endosymbiont of Brugia malayi dihydrolipoamide dehydrogenase E3 component 0.0323 0.3179 1
Mycobacterium tuberculosis Probable soluble pyridine nucleotide transhydrogenase SthA (STH) (NAD(P)(+) transhydrogenase [B-specific]) (nicotinamide nucleot 0.0323 0.3179 0.5132
Trypanosoma cruzi Present in the outer mitochondrial membrane proteome 4 0.0035 0.0225 0.0248
Schistosoma mansoni calcium-activated potassium channel 0.0036 0.0234 0.0254
Echinococcus granulosus rhodopsin orphan GPCR 0.0135 0.1244 0.1244
Schistosoma mansoni voltage-gated potassium channel 0.0036 0.0234 0.0254
Brugia malayi Nuclear hormone receptor family member nhr-31 0.0021 0.0076 0.0123
Mycobacterium leprae PROBABLE NADPH:ADRENODOXIN OXIDOREDUCTASE FPRB (ADRENODOXIN REDUCTASE) (AR) (FERREDOXIN-NADP(+) REDUCTASE) 0.0086 0.0743 0.1589
Loa Loa (eye worm) hypothetical protein 0.008 0.0686 0.1113
Mycobacterium leprae THIOREDOXIN TRXC (TRX) (MPT46) 0.0086 0.0743 0.1589
Schistosoma mansoni microtubule-associated protein tau 0.0711 0.7159 0.7778
Schistosoma mansoni protein kinase 0.0029 0.0159 0.0172
Onchocerca volvulus 0.0042 0.0296 0.0942
Entamoeba histolytica fructose-1,6-bisphosphate aldolase, putative 0.0301 0.2953 1
Schistosoma mansoni hypothetical protein 0.007 0.0584 0.0634
Leishmania major beta tubulin 0.0026 0.0131 0.0134
Schistosoma mansoni tyrosine kinase 0.0082 0.0701 0.0761
Schistosoma mansoni histone-lysine n-methyltransferase suv9 0.0043 0.0305 0.0331
Leishmania major beta tubulin 0.0026 0.0131 0.0134
Plasmodium vivax FAD-linked sulfhydryl oxidase ERV1, putative 0.0035 0.0225 0.0319
Mycobacterium tuberculosis NADPH-dependent mycothiol reductase Mtr 0.0615 0.6166 1
Loa Loa (eye worm) hypothetical protein 0.0135 0.1244 0.2018
Loa Loa (eye worm) hypothetical protein 0.0135 0.1244 0.2018
Schistosoma mansoni opsin-like receptor 0.0135 0.1244 0.1352
Mycobacterium tuberculosis Probable dehydrogenase 0.0193 0.1837 0.2946
Brugia malayi Serotonin/octopamine receptor family protein 7 0.044 0.4371 0.709
Echinococcus granulosus rhodopsin orphan GPCR 0.0135 0.1244 0.1244
Echinococcus granulosus insulin receptor 0.005 0.0377 0.0377
Mycobacterium ulcerans NADH dehydrogenase Ndh1 0.0086 0.0743 0.2186
Echinococcus granulosus metabotropic glutamate receptor 2 0.0023 0.0103 0.0103
Echinococcus granulosus calcium activated potassium channel 0.0037 0.0239 0.0239
Schistosoma mansoni hypothetical protein 0.0175 0.1654 0.1797
Schistosoma mansoni amine GPCR 0.0135 0.1244 0.1352
Echinococcus granulosus survival motor neuron protein 1 0.0244 0.2363 0.2363
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0021 0.0076 0.0123
Loa Loa (eye worm) melatonin receptor type 1A 0.0135 0.1244 0.2018
Brugia malayi Nuclear hormone receptor family member nhr-40 0.0021 0.0076 0.0123
Onchocerca volvulus 0.0135 0.1244 0.4987
Schistosoma mansoni thyroid hormone receptor 0.0021 0.0076 0.0082
Chlamydia trachomatis Ssodium-dependent amino acid transporter 0.0042 0.0296 0.0608
Trichomonas vaginalis myo inositol monophosphatase, putative 0.0038 0.0253 0.0752
Mycobacterium ulcerans DNA gyrase subunit B 0.0084 0.0724 0.2127
Echinococcus granulosus rhodopsin orphan GPCR 0.0135 0.1244 0.1244
Echinococcus granulosus sodium channel protein 0.0439 0.4364 0.4364
Echinococcus granulosus potassium large conductance calcium activated 0.0036 0.0234 0.0234
Schistosoma mansoni growth hormone secretagogue receptor 0.0135 0.1244 0.1352
Wolbachia endosymbiont of Brugia malayi dihydrolipoamide dehydrogenase E3 component 0.0323 0.3179 1
Loa Loa (eye worm) hypothetical protein 0.0028 0.0148 0.0239
Echinococcus multilocularis sex peptide receptor 0.0135 0.1244 0.1244
Trypanosoma brucei apurinic/apyrimidinic endonuclease, putative 0.0019 0.0061 0.0048
Trichomonas vaginalis dihydroorotate dehydrogenase, putative 0.0086 0.0743 0.23
Trichomonas vaginalis PIKK family atypical protein kinase 0.0046 0.0338 0.102
Echinococcus multilocularis sodium and chloride dependent glycine 0.0042 0.0296 0.0296
Echinococcus multilocularis glutamate receptor 2 0.0167 0.1574 0.1574
Trypanosoma cruzi DNA topoisomerase II, putative 0.0136 0.1261 0.1511
Echinococcus multilocularis neuropeptide receptor 0.0135 0.1244 0.1244
Echinococcus multilocularis atrial natriuretic peptide receptor 0.0023 0.0103 0.0103
Schistosoma mansoni tubulin subunit beta 0.0026 0.0131 0.0142
Echinococcus multilocularis rhodopsin orphan GPCR 0.0135 0.1244 0.1244
Trichomonas vaginalis CMGC family protein kinase 0.0053 0.0401 0.1221
Brugia malayi SET domain containing protein 0.0014 0.0001 0.0002
Loa Loa (eye worm) hypothetical protein 0.0021 0.0076 0.0123
Schistosoma mansoni retinoic acid receptor RXR 0.0021 0.0076 0.0082
Echinococcus granulosus Tubulin beta 2C chain 0.0026 0.0131 0.0131
Brugia malayi Steroid receptor seven-up type 2 0.0021 0.0076 0.0123
Schistosoma mansoni intermediate filament proteins 0.0028 0.0148 0.016
Trypanosoma brucei hypothetical protein, conserved 0.0024 0.011 0.0107
Loa Loa (eye worm) hypothetical protein 0.0135 0.1244 0.2018
Echinococcus multilocularis shaker cognate 0.0036 0.0234 0.0234
Loa Loa (eye worm) hypothetical protein 0.0023 0.0103 0.0168
Echinococcus multilocularis tubulin beta 1 chain 0.0026 0.0131 0.0131
Loa Loa (eye worm) hypothetical protein 0.0036 0.0234 0.0379
Echinococcus granulosus voltage dependent calcium channel 0.0054 0.0421 0.0421
Toxoplasma gondii NADH dehydrogenase (NDH2-II) 0.0086 0.0743 0.1162
Echinococcus granulosus sodium and chloride dependent glycine 0.0042 0.0296 0.0296
Brugia malayi G-protein-linked acetylcholine receptor protein 2, putative 0.0135 0.1244 0.2018
Trypanosoma brucei DNA topoisomerase II alpha, putative 0.0136 0.1261 0.1511
Trypanosoma cruzi dihydrolipoyl dehydrogenase, putative 0.0323 0.3179 0.385
Brugia malayi Tachykinin-like peptides receptor 99D 0.0135 0.1244 0.2018
Plasmodium falciparum ataxin-2 like protein, putative 0.0026 0.0129 0.0162
Leishmania major calmodulin, putative 0.0025 0.0121 0.0121
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0021 0.0076 0.0123
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0021 0.0076 0.0123
Loa Loa (eye worm) programmed cell death 8 0.0086 0.0743 0.1205
Loa Loa (eye worm) hypothetical protein 0.0135 0.1244 0.2018
Trichomonas vaginalis glucosylceramidase, putative 0.0175 0.1654 0.5181
Schistosoma mansoni transient receptor potential cation channel subfamily m member 0.0036 0.0234 0.0254
Leishmania major dihydrolipoamide dehydrogenase, putative 0.0323 0.3179 0.385
Mycobacterium tuberculosis Probable oxidoreductase 0.043 0.4273 0.6916
Trypanosoma cruzi calmodulin, putative 0.0025 0.0121 0.0121
Brugia malayi ERG2 and Sigma1 receptor like protein 0.038 0.3756 0.6091
Echinococcus multilocularis potassium voltage gated channel subfamily D 0.0036 0.0234 0.0234
Loa Loa (eye worm) hypothetical protein 0.0135 0.1244 0.2018
Echinococcus multilocularis dihydropyrimidine dehydrogenase (NADP+) 0.0086 0.0743 0.0743
Mycobacterium ulcerans sugar phosphate isomerases/epimerases 0.0021 0.0076 0.0046
Echinococcus multilocularis calmodulin 0.0025 0.0121 0.0121
Echinococcus multilocularis RUN 0.0041 0.0279 0.0279
Echinococcus multilocularis tubulin, beta 4A class IVa 0.0026 0.0131 0.0131
Trichomonas vaginalis glucosylceramidase, putative 0.0175 0.1654 0.5181
Mycobacterium ulcerans phosphopantetheinyl transferase, PptII 0.0024 0.011 0.0155
Leishmania major DNA topoisomerase ii 0.0136 0.1261 0.1511
Loa Loa (eye worm) TK protein kinase 0.0036 0.0231 0.0374
Trypanosoma brucei pyridine nucleotide-disulphide oxidoreductase, putative 0.0086 0.0743 0.0879
Mycobacterium ulcerans thioredoxin reductase TrxB2 0.0086 0.0743 0.2186
Echinococcus granulosus dihydropyrimidine dehydrogenase NADP 0.0086 0.0743 0.0743
Loa Loa (eye worm) serotonin transporter b 0.0249 0.2419 0.3923
Loa Loa (eye worm) hypothetical protein 0.0249 0.2419 0.3923
Loa Loa (eye worm) hypothetical protein 0.0135 0.1244 0.2018
Trypanosoma cruzi mitogen activated protein kinase 4, putative 0.0053 0.0401 0.0463
Echinococcus granulosus atrial natriuretic peptide receptor 0.0023 0.0103 0.0103
Echinococcus granulosus Tubulin beta 2C chain 0.0026 0.0131 0.0131
Loa Loa (eye worm) hypothetical protein 0.0135 0.1244 0.2018
Treponema pallidum NADH oxidase 0.0323 0.3179 1
Onchocerca volvulus 0.0042 0.0296 0.0942
Schistosoma mansoni jumonji domain containing protein 0.0078 0.0664 0.0722
Trichomonas vaginalis inositol monophosphatase, putative 0.0038 0.0253 0.0752
Trichomonas vaginalis disulfide oxidoreductase, putative 0.0086 0.0743 0.23
Echinococcus multilocularis sodium dependent neurotransmitter transporter 0.0042 0.0296 0.0296
Onchocerca volvulus 0.0135 0.1244 0.4987
Echinococcus multilocularis serotonin receptor 0.0386 0.382 0.382
Trichomonas vaginalis PIKK family atypical protein kinase 0.0034 0.0216 0.0635
Echinococcus multilocularis lipoxygenase domain containing protein 0.0041 0.0279 0.0279
Echinococcus granulosus beta tubulin 0.0026 0.0131 0.0131
Echinococcus multilocularis NADP dependent isocitrate dehydrogenase 0.0016 0.0029 0.0029
Loa Loa (eye worm) hypothetical protein 0.0026 0.0129 0.0209
Entamoeba histolytica NAD(FAD)-dependent dehydrogenase, putative 0.0086 0.0743 0.2357
Mycobacterium ulcerans carbon monoxyde dehydrogenase medium chain CoxM 0.006 0.0481 0.1346
Brugia malayi ion channel NompC 0.0036 0.0234 0.0378
Toxoplasma gondii beta-tubulin, putative 0.0026 0.0131 0.0166
Brugia malayi Nuclear hormone receptor family member nhr-14 0.0021 0.0076 0.0123
Onchocerca volvulus 0.0023 0.0103 0.0119
Trichomonas vaginalis PIKK family atypical protein kinase 0.0046 0.0338 0.102
Brugia malayi GnHR receptor homolog 0.0135 0.1244 0.2018
Echinococcus granulosus biogenic amine 5HT receptor 0.0386 0.382 0.382
Brugia malayi Isocitrate dehydrogenase 0.0016 0.0029 0.0047
Schistosoma mansoni tyrosine kinase 0.005 0.0377 0.041
Loa Loa (eye worm) MH2 domain-containing protein 0.0123 0.1125 0.1824
Echinococcus granulosus tyrosine kinase 0.0025 0.0123 0.0123
Trypanosoma brucei NADH dehydrogenase 0.0086 0.0743 0.0879
Brugia malayi hypothetical protein 0.0135 0.1244 0.2018
Plasmodium vivax SET domain protein, putative 0.0031 0.0185 0.0253
Trichomonas vaginalis aldehyde oxidase, putative 0.0179 0.1695 0.5309
Echinococcus granulosus phosphatidylinositol 3 and 4 kinase 0.0016 0.0022 0.0022
Leishmania major calcium channel protein, putative,ion transporter, putative 0.0439 0.4364 0.5296
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0707 0.7112 0.8647
Echinococcus granulosus melanoma receptor tyrosine protein kinase 0.0084 0.0721 0.0721
Brugia malayi Dopamine receptor protein 1 0.0562 0.5622 0.9119
Schistosoma mansoni neuropeptide F-like receptor 0.0135 0.1244 0.1352
Schistosoma mansoni hypothetical protein 0.0086 0.0743 0.0807
Schistosoma mansoni tubulin subunit beta 0.0026 0.0131 0.0142
Loa Loa (eye worm) hypothetical protein 0.0135 0.1244 0.2018
Loa Loa (eye worm) Sodium:neurotransmitter symporter family protein 0.0042 0.0296 0.0481
Echinococcus granulosus transient receptor potential cation channel 0.0036 0.0234 0.0234
Echinococcus multilocularis tachykinin peptides receptor 99D 0.0135 0.1244 0.1244
Plasmodium vivax hypothetical protein, conserved 0.003 0.0171 0.023
Trichomonas vaginalis tubulin, putative 0.0026 0.0131 0.0368
Chlamydia trachomatis endonuclease IV 0.0079 0.0673 0.1835
Toxoplasma gondii hypothetical protein 0.0036 0.0234 0.0333
Echinococcus multilocularis Glutamate receptor, ionotropic kainate 2 0.019 0.1815 0.1815
Schistosoma mansoni ap endonuclease 0.0019 0.0061 0.0066
Loa Loa (eye worm) heterochromatin protein 1 0.0072 0.0599 0.0972
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0135 0.1244 0.1352
Echinococcus multilocularis NADP dependent isocitrate dehydrogenase 0.0016 0.0029 0.0029
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0031 0.0185 0.02
Schistosoma mansoni nuclear hormone receptor nor-1/nor-2 0.0021 0.0076 0.0082
Loa Loa (eye worm) hypothetical protein 0.0023 0.0103 0.0168
Leishmania major beta tubulin 0.0026 0.0131 0.0134
Trypanosoma cruzi trypanothione reductase, putative 0.0323 0.3179 0.385
Chlamydia trachomatis DNA gyrase subunit B 0.0066 0.0543 0.1413
Mycobacterium ulcerans monoxygenase 0.0086 0.0743 0.2186
Plasmodium vivax AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.0019 0.0061 0.0052
Schistosoma mansoni ancient conserved domain protein 2 (cyclin m2) 0.0135 0.1244 0.1352
Echinococcus granulosus transcription factor Dp 1 0.0039 0.0266 0.0266
Echinococcus multilocularis L aminoadipate semialdehyde 0.0086 0.0741 0.0741
Trypanosoma cruzi 2,4-dienoyl-coa reductase-like protein, putative 0.0086 0.0743 0.0879
Onchocerca volvulus Neuropeptide F receptor homolog 0.0135 0.1244 0.4987
Schistosoma mansoni NADP-specific isocitrate dehydrogenase 0.0016 0.0029 0.0032
Mycobacterium tuberculosis Probable membrane NADH dehydrogenase NdhA 0.0193 0.1837 0.2946
Loa Loa (eye worm) hypothetical protein 0.0135 0.1244 0.2018
Echinococcus multilocularis epidermal growth factor receptor 0.0155 0.145 0.145
Trichomonas vaginalis glucosylceramidase, putative 0.0175 0.1654 0.5181
Leishmania major hypothetical protein, conserved 0.0036 0.0234 0.0258
Echinococcus granulosus DNA topoisomerase 2 alpha 0.0144 0.134 0.134
Loa Loa (eye worm) hypothetical protein 0.0036 0.0234 0.0379
Brugia malayi MH2 domain containing protein 0.0123 0.1125 0.1824
Trypanosoma cruzi ferric reductase transmembrane protein, putative 0.0035 0.0223 0.0245
Echinococcus multilocularis tumor protein p63 0.0348 0.3435 0.3435
Trichomonas vaginalis disulfide oxidoreductase, putative 0.0086 0.0743 0.23
Onchocerca volvulus DNA topoisomerase 2 homolog 0.0097 0.0861 0.3352
Echinococcus granulosus hypothetical protein 0.0846 0.8541 0.8541
Schistosoma mansoni inositol monophosphatase 0.0038 0.0253 0.0275
Trypanosoma brucei ERV/ALR sulfhydryl oxidase domain-containing protein 0.0035 0.0225 0.0248
Brugia malayi Doublecortin family protein 0.0041 0.0279 0.0453
Echinococcus granulosus lipoxygenase domain containing protein 0.0041 0.0279 0.0279
Mycobacterium ulcerans carbon monoxyde dehydrogenase small chain CoxS 0.0034 0.0212 0.0484
Brugia malayi jmjC domain containing protein 0.0098 0.0872 0.1414
Loa Loa (eye worm) pyridine nucleotide-disufhide oxidoreductase 0.0086 0.0743 0.1205
Echinococcus multilocularis potassium voltage gated channel protein 0.0036 0.0234 0.0234
Brugia malayi chromobox protein homolog 3 0.004 0.0275 0.0446
Brugia malayi hypothetical protein 0.0135 0.1244 0.2018
Schistosoma mansoni hypothetical protein 0.0175 0.1654 0.1797
Loa Loa (eye worm) hypothetical protein 0.0018 0.0049 0.008
Echinococcus multilocularis potassium voltage gated channel protein 0.0036 0.0234 0.0234
Trichomonas vaginalis PIKK family atypical protein kinase 0.0028 0.0146 0.0416
Echinococcus multilocularis g protein linked acetylcholine receptor gar 2a 0.0135 0.1244 0.1244
Loa Loa (eye worm) hypothetical protein 0.0135 0.1244 0.2018
Echinococcus granulosus calmodulin 0.0025 0.0121 0.0121
Trypanosoma brucei pyridine nucleotide-disulphide oxidoreductase, putative 0.0086 0.0743 0.0879
Plasmodium falciparum LCCL domain-containing protein 0.0041 0.0279 0.0407
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0021 0.0076 0.0123
Echinococcus granulosus FTZ F1 alpha 0.0021 0.0076 0.0076
Echinococcus granulosus two pore calcium channel protein 1 0.0036 0.0234 0.0234
Onchocerca volvulus 0.0135 0.1244 0.4987
Loa Loa (eye worm) hypothetical protein 0.0135 0.1244 0.2018
Loa Loa (eye worm) hypothetical protein 0.0135 0.1244 0.2018
Echinococcus multilocularis diuretic hormone 44 receptor GPRdih2 0.0016 0.0029 0.0029
Mycobacterium ulcerans NADPH:adrenodoxin oxidoreductase FprA 0.0086 0.0743 0.2186
Trichomonas vaginalis ap endonuclease, putative 0.0019 0.0061 0.0147
Trichomonas vaginalis xanthine dehydrogenase, putative 0.0179 0.1695 0.5309
Schistosoma mansoni thyroid hormone receptor 0.0021 0.0076 0.0082
Brugia malayi cation channel family protein 0.0036 0.0234 0.0378
Echinococcus granulosus tyrosine protein kinase Fyn 0.004 0.0269 0.0269
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0064 0.0518 0.0563
Brugia malayi Dopamine receptor 0.0135 0.1244 0.2018
Trichomonas vaginalis voltage and ligand gated potassium channel, putative 0.0047 0.0348 0.1054
Loa Loa (eye worm) hypothetical protein 0.0054 0.0421 0.0682
Trypanosoma brucei isocitrate dehydrogenase, putative 0.0016 0.0029 0.0009
Echinococcus multilocularis chromobox protein 1 0.0072 0.0599 0.0599
Schistosoma mansoni tyrosine kinase 0.0084 0.0721 0.0783
Echinococcus granulosus potassium voltage gated channel protein 0.0036 0.0234 0.0234
Brugia malayi Melatonin receptor type 1A 0.0135 0.1244 0.2018
Schistosoma mansoni aminoadipate-semialdehyde dehydrogenase 0.0086 0.0741 0.0805
Echinococcus multilocularis conserved hypothetical protein 0.0711 0.7159 0.7159
Brugia malayi Transient-receptor-potential like protein 0.0036 0.0234 0.0378
Trypanosoma brucei beta tubulin 0.0026 0.0131 0.0134
Schistosoma mansoni lipoxygenase 0.0105 0.0943 0.1024
Giardia lamblia NADH oxidase lateral transfer candidate 0.0323 0.3179 1
Schistosoma mansoni amine GPCR 0.0135 0.1244 0.1352
Trichomonas vaginalis PIKK family atypical protein kinase 0.0034 0.0216 0.0635
Loa Loa (eye worm) nuclear hormone receptor family member nhr-49 0.0021 0.0076 0.0123
Echinococcus granulosus tm gpcr rhodopsin 0.0135 0.1244 0.1244
Mycobacterium ulcerans carbon monoxyde dehydrogenase small chain CoxS 0.0034 0.0212 0.0484
Echinococcus multilocularis pyroglutamylated rfamide peptide receptor 0.0135 0.1244 0.1244
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0135 0.1244 0.1352
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0015 0.002 0.0016
Schistosoma mansoni tubulin subunit beta 0.0026 0.0131 0.0142
Mycobacterium ulcerans extragenic suppressor protein SuhB 0.0038 0.0253 0.0615
Loa Loa (eye worm) hypothetical protein 0.0036 0.0234 0.0379
Trypanosoma brucei 2,4-dienoyl-coa reductase-like protein 0.0086 0.0743 0.0879
Schistosoma mansoni sodium/chloride dependent transporter 0.0043 0.0301 0.0327
Echinococcus granulosus PHD finger protein rhinoceros 0.003 0.0171 0.0171
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0018 0.0052 0.0117
Toxoplasma gondii PHD-finger domain-containing protein 0.003 0.0171 0.023
Brugia malayi Pre-SET motif family protein 0.0031 0.0185 0.0299
Echinococcus multilocularis lysine specific demethylase 5A 0.0036 0.0236 0.0236
Trichomonas vaginalis mercuric reductase, putative 0.0323 0.3179 1
Brugia malayi hypothetical protein 0.0068 0.056 0.0907
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0815 0.8221 1
Brugia malayi photoreceptor-specific nuclear receptor 0.0021 0.0076 0.0123
Leishmania major mitochondrial DNA topoisomerase II 0.0162 0.1521 0.1829
Loa Loa (eye worm) hypothetical protein 0.0036 0.0234 0.0379
Trypanosoma brucei cytochrome P450, putative 0.002 0.0067 0.0056
Trypanosoma brucei PAB1-binding protein , putative 0.0026 0.0129 0.0131
Entamoeba histolytica tubulin family protein 0.0026 0.0131 0.0243
Schistosoma mansoni transient receptor potential cation channel subfamily m member 0.0036 0.0234 0.0254
Leishmania major beta tubulin 0.0026 0.0131 0.0134
Loa Loa (eye worm) hypothetical protein 0.0042 0.0296 0.0481
Echinococcus multilocularis cyclic nucleotide gated cation channel alpha 3 0.0041 0.0285 0.0285
Loa Loa (eye worm) hypothetical protein 0.003 0.0171 0.0277
Brugia malayi Bromodomain containing protein 0.003 0.0171 0.0276
Echinococcus granulosus transient receptor potential cation channel 0.0036 0.0234 0.0234
Schistosoma mansoni nuclear hormone receptor 0.0021 0.0076 0.0082
Loa Loa (eye worm) hypothetical protein 0.0018 0.0049 0.008
Toxoplasma gondii thioredoxin reductase 0.0615 0.6166 1
Trypanosoma brucei phosphatidylinositol 3-kinase tor, putative 0.0022 0.0087 0.008
Schistosoma mansoni peptide (FMRFamide/somatostatin)-like receptor 0.0135 0.1244 0.1352
Loa Loa (eye worm) hypothetical protein 0.0098 0.0863 0.1399
Loa Loa (eye worm) hypothetical protein 0.0194 0.1852 0.3004
Mycobacterium ulcerans NADPH dependent 2,4-dienoyl-CoA reductase FadH 0.0086 0.0743 0.2186
Trichomonas vaginalis PIKK family atypical protein kinase 0.004 0.0268 0.08
Trypanosoma brucei dihydrolipoamide dehydrogenase 0.0707 0.7112 0.8647
Schistosoma mansoni voltage-gated potassium channel 0.004 0.0269 0.0292
Trypanosoma cruzi inositol 1,4,5-trisphosphate receptor, putative 0.0036 0.0234 0.0258
Brugia malayi Receptor family ligand binding region containing protein 0.0029 0.0159 0.0257
Echinococcus granulosus neuropeptides capa receptor 0.0135 0.1244 0.1244
Trypanosoma cruzi isocitrate dehydrogenase, putative 0.0016 0.0029 0.0009
Echinococcus granulosus jun protein 0.0087 0.075 0.075
Mycobacterium ulcerans ferredoxin reductase 0.0086 0.0743 0.2186
Echinococcus multilocularis nmda type glutamate receptor 0.0105 0.0937 0.0937
Loa Loa (eye worm) hypothetical protein 0.0135 0.1244 0.2018
Echinococcus multilocularis DNA topoisomerase 2 alpha 0.0144 0.134 0.134
Echinococcus granulosus nmda type glutamate receptor 0.0105 0.0937 0.0937
Onchocerca volvulus 0.0135 0.1244 0.4987
Loa Loa (eye worm) hypothetical protein 0.0036 0.0234 0.0379
Loa Loa (eye worm) hypothetical protein 0.0023 0.0103 0.0168
Mycobacterium tuberculosis Conserved hypothetical protein 0.0021 0.0076 0.0075
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0135 0.1244 0.1352
Plasmodium vivax amine transporter, putative 0.0042 0.0296 0.0435
Echinococcus granulosus sodium:chloride dependent neurotransmitter 0.0042 0.0296 0.0296
Schistosoma mansoni biogenic amine receptor 0.0135 0.1244 0.1352
Loa Loa (eye worm) solute carrier family 6 member 4 0.0249 0.2419 0.3923
Echinococcus multilocularis neuropeptide receptor 0.0135 0.1244 0.1244
Mycobacterium ulcerans hypothetical protein 0.0086 0.0743 0.2186
Plasmodium falciparum NAD(P)H-dependent glutamate synthase, putative 0.0086 0.0743 0.1162
Chlamydia trachomatis glutamine binding protein 0.0039 0.0262 0.0497
Loa Loa (eye worm) hypothetical protein 0.0135 0.1244 0.2018
Entamoeba histolytica glutamate synthase beta subunit, putative 0.0086 0.0743 0.2357
Echinococcus multilocularis TRP (transient receptor potential) channel 0.0036 0.0234 0.0234
Echinococcus multilocularis beta tubulin 0.0026 0.0131 0.0131
Brugia malayi Voltage-gated potassium channel, HERG (KCNH2)-related. C. elegans unc-103 ortholog 0.0072 0.0598 0.0969
Onchocerca volvulus 0.0041 0.0279 0.087
Leishmania major extracellular receptor, putative 0.0023 0.0103 0.01
Onchocerca volvulus Transient receptor potential cation channel trpm homolog 0.0036 0.0234 0.0675
Echinococcus multilocularis FTZ F1 nuclear receptor protein 0.0021 0.0076 0.0076
Loa Loa (eye worm) neuropeptide F receptor 0.0135 0.1244 0.2018
Onchocerca volvulus 0.0028 0.0148 0.0307
Trichomonas vaginalis PIKK family atypical protein kinase 0.0034 0.0216 0.0635
Trichomonas vaginalis set domain proteins, putative 0.0245 0.2374 0.7455
Echinococcus granulosus potassium voltage gated channel protein 0.0036 0.0234 0.0234
Trypanosoma brucei dihydrolipoamide dehydrogenase 0.0815 0.8221 1
Loa Loa (eye worm) metabotropic glutamate receptor 8 0.0023 0.0103 0.0168
Schistosoma mansoni FTZ-F1 nuclear receptor-like protein 0.0021 0.0076 0.0082
Loa Loa (eye worm) tubulin beta chain 0.0026 0.0131 0.0213
Echinococcus multilocularis Glutamate receptor, ionotropic kainate 2 0.019 0.1815 0.1815
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0135 0.1244 0.1352
Echinococcus multilocularis sodium and chloride dependent glycine 0.0042 0.0296 0.0296
Leishmania major isocitrate dehydrogenase [NADP], mitochondrial precursor, putative 0.0016 0.0029 0.0009
Onchocerca volvulus 0.0068 0.056 0.2066
Leishmania major ferric reductase, putative 0.0035 0.0223 0.0245
Trypanosoma cruzi Phosphatidylinositol 3-kinase tor1 0.0046 0.0338 0.0385
Onchocerca volvulus Heterochromatin protein 1 homolog 0.004 0.0275 0.0853
Echinococcus multilocularis voltage gated potassium channel 0.0045 0.0321 0.0321
Plasmodium vivax type II NADH:ubiquinone oxidoreductase, putative 0.0086 0.0743 0.1162
Mycobacterium leprae conserved hypothetical protein 0.0024 0.011 0.0081
Loa Loa (eye worm) phosphatidylinositol 3 0.0016 0.0022 0.0035
Echinococcus multilocularis inositol monophosphatase 1 0.0038 0.0253 0.0253
Echinococcus granulosus hyperpolarization activated cyclic 0.0041 0.0285 0.0285
Echinococcus granulosus rhodopsin orphan GPCR 0.0135 0.1244 0.1244
Echinococcus granulosus mitogen activated protein kinase 3 0.0053 0.0401 0.0401
Schistosoma mansoni rab6-interacting 0.0041 0.0279 0.0303
Echinococcus multilocularis transient receptor potential cation channel 0.0036 0.0236 0.0236
Loa Loa (eye worm) jmjC domain-containing protein 0.0062 0.0499 0.0809
Schistosoma mansoni neuropeptide receptor 0.0135 0.1244 0.1352
Treponema pallidum oxidoreductase 0.0086 0.0743 0.2186
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0634 0.6369 0.7742
Schistosoma mansoni jun-related protein 0.007 0.0584 0.0634
Echinococcus multilocularis G protein coupled receptor 139 0.0135 0.1244 0.1244
Leishmania major target of rapamycin (TOR) kinase 1, putative 0.0046 0.0338 0.0385
Trypanosoma brucei ferric reductase transmembrane protein, putative 0.0035 0.0223 0.0245
Trichomonas vaginalis glucosylceramidase, putative 0.0266 0.2593 0.8149
Wolbachia endosymbiont of Brugia malayi 4'-phosphopantetheinyl transferase 0.0024 0.011 0.0155
Schistosoma mansoni tyrosine kinase 0.0025 0.0123 0.0134
Trypanosoma brucei calmodulin 0.0025 0.0121 0.0121
Trichomonas vaginalis glucosylceramidase, putative 0.0175 0.1654 0.5181
Echinococcus granulosus adenylate cyclase 9 0.008 0.0686 0.0686
Mycobacterium tuberculosis Probable carbon monoxyde dehydrogenase (medium chain) 0.006 0.0481 0.0736
Mycobacterium ulcerans carbon monoxyde dehydrogenase large chain CoxL 0.0084 0.0726 0.2133
Schistosoma mansoni sodium/chloride dependent transporter 0.0249 0.2419 0.2628
Trypanosoma cruzi apurinic/apyrimidinic endonuclease 0.0019 0.0061 0.0048
Giardia lamblia Beta tubulin 0.0026 0.0131 0.0225
Echinococcus granulosus retinoic acid receptor rxr beta a 0.0021 0.0076 0.0076
Loa Loa (eye worm) hypothetical protein 0.0135 0.1244 0.2018
Trichomonas vaginalis tubulin epsilon chain, putative 0.0026 0.0131 0.0368
Entamoeba histolytica glutamate synthase beta subunit, putative 0.0086 0.0743 0.2357
Loa Loa (eye worm) receptor family ligand binding region containing protein 0.0023 0.0103 0.0168
Echinococcus multilocularis tyrosine protein kinase Src42A 0.004 0.0269 0.0269
Plasmodium vivax ferrodoxin reductase, putative 0.0086 0.0743 0.1162
Trypanosoma cruzi tyrosyl-DNA Phosphodiesterase (Tdp1), putative 0.0068 0.056 0.0657
Leishmania major beta tubulin 0.0026 0.0131 0.0134
Echinococcus multilocularis tyrosine protein kinase HCK 0.0032 0.0191 0.0191
Mycobacterium tuberculosis Probable reductase 0.0193 0.1837 0.2946
Leishmania major beta tubulin 0.0026 0.0131 0.0134
Echinococcus multilocularis fmrfamide receptor 0.0135 0.1244 0.1244
Echinococcus granulosus mitogen activated protein kinase 0.0053 0.0401 0.0401
Schistosoma mansoni hypothetical protein 0.0135 0.1244 0.1352
Leishmania major target of rapamycin (TOR) kinase 2, putative 0.0046 0.0338 0.0385
Loa Loa (eye worm) hypothetical protein 0.0135 0.1244 0.2018
Onchocerca volvulus 0.0042 0.0296 0.0942
Toxoplasma gondii hypothetical protein 0.0036 0.0234 0.0333
Mycobacterium tuberculosis Probable glutamine-binding lipoprotein GlnH (GLNBP) 0.0039 0.0262 0.0379
Brugia malayi neuropeptide F receptor 0.0135 0.1244 0.2018
Onchocerca volvulus 0.0135 0.1244 0.4987
Echinococcus multilocularis transient receptor potential cation channel 0.0036 0.0234 0.0234
Wolbachia endosymbiont of Brugia malayi fructose-1,6-bisphosphatase 0.0038 0.0253 0.0615
Loa Loa (eye worm) intermediate filament protein 0.0028 0.0148 0.0239
Trypanosoma brucei DNA topoisomerase II beta, putative 0.0136 0.1261 0.1511
Brugia malayi Nuclear hormone receptor family member nhr-41 0.0021 0.0076 0.0123
Leishmania major myo-inositol-1(or 4)-monophosphatase 1, putative 0.0038 0.0253 0.0282
Schistosoma mansoni cpg binding protein 0.0031 0.0183 0.0199
Onchocerca volvulus 0.0086 0.0741 0.2842
Loa Loa (eye worm) SRC-1 0.004 0.0269 0.0437
Trypanosoma cruzi PAB1-binding protein , putative 0.0026 0.0129 0.0131
Loa Loa (eye worm) voltage and ligand gated potassium channel 0.0072 0.0598 0.097
Schistosoma mansoni disulfide oxidoreductase 0.0086 0.0743 0.0807
Loa Loa (eye worm) hypothetical protein 0.0042 0.0296 0.0481
Schistosoma mansoni hyperpolarization activated cyclic nucleotide-gated potassium channel 0.0036 0.0234 0.0254
Leishmania major 2,4-dienoyl-coa reductase fadh1, putative 0.0086 0.0743 0.0879
Leishmania major hypothetical protein, conserved 0.0026 0.0129 0.0131
Trichomonas vaginalis disulfide oxidoreductase, putative 0.0086 0.0743 0.23
Brugia malayi Guanylyl cyclase protein 23 0.0029 0.0159 0.0257
Trichomonas vaginalis glutamate synthase, putative 0.0086 0.0743 0.23
Brugia malayi hypothetical protein 0.0135 0.1244 0.2018
Trichomonas vaginalis PIKK family atypical protein kinase 0.0025 0.0119 0.0329
Echinococcus granulosus g-protein coupled receptor 0.0135 0.1244 0.1244
Echinococcus multilocularis mitogen activated protein kinase 0.0053 0.0401 0.0401
Brugia malayi Voltage-gated potassium channel, Shab-family (KCNB, Kv2-like) alpha-subunit. C. elegans exp-2 ortholog 0.0036 0.0234 0.0378
Onchocerca volvulus 0.0028 0.0148 0.0307
Loa Loa (eye worm) TK/INSR protein kinase 0.005 0.0377 0.0612
Trichomonas vaginalis chromobox protein, putative 0.0043 0.0307 0.0922
Trichomonas vaginalis dihydrolipoamide dehydrogenase, putative 0.0086 0.0743 0.23
Loa Loa (eye worm) hypothetical protein 0.0135 0.1244 0.2018
Brugia malayi Receptor family ligand binding region containing protein 0.0023 0.0103 0.0167
Schistosoma mansoni loxhd1 0.0041 0.0279 0.0303
Echinococcus multilocularis voltage dependent calcium channel 0.0133 0.1224 0.1224
Leishmania major beta tubulin 0.0026 0.0131 0.0134
Echinococcus multilocularis calmodulin 0.0025 0.0121 0.0121
Echinococcus granulosus ryanodine receptor 44f 0.0036 0.0234 0.0234
Leishmania major 2-oxoglutarate dehydrogenase, e3 component, lipoamidedehydrogenase-like protein 0.0707 0.7112 0.8647
Trypanosoma brucei calmodulin 0.0025 0.0121 0.0121
Chlamydia trachomatis DNA gyrase subunit A 0.0031 0.018 0.023
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0301 0.2953 0.9285
Echinococcus granulosus neuropeptide FF receptor 2 0.0135 0.1244 0.1244
Trichomonas vaginalis voltage and ligand gated potassium channel, putative 0.0047 0.0348 0.1054
Echinococcus granulosus neuropeptide receptor 0.0135 0.1244 0.1244
Echinococcus multilocularis tyrosyl DNA phosphodiesterase 1 0.0068 0.056 0.056
Trypanosoma cruzi pyridine nucleotide-disulphide oxidoreductase, putative 0.0086 0.0743 0.0879
Loa Loa (eye worm) hypothetical protein 0.0021 0.0076 0.0123
Brugia malayi Dopamine receptor protein 2 0.0135 0.1244 0.2018
Brugia malayi ecdysteroid receptor 0.0021 0.0076 0.0123
Schistosoma mansoni thyrotropin-releasing hormone receptor 0.0135 0.1244 0.1352
Schistosoma mansoni tyrosine kinase 0.0084 0.0721 0.0783
Leishmania major NADH dehydrogenase, putative 0.0086 0.0743 0.0879
Brugia malayi Voltage-gated potassium channel, Shaker-family (KCNA, Kv1-like) alpha-subunit 0.0036 0.0234 0.0378
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0988 1 1
Mycobacterium ulcerans flavoprotein disulfide reductase 0.0323 0.3179 1
Loa Loa (eye worm) cytochrome P450 family protein 0.002 0.0067 0.0109
Schistosoma mansoni sodium/chloride dependent neurotransmitter transporter 0.0042 0.0296 0.0322
Trichomonas vaginalis PIKK family atypical protein kinase 0.0025 0.0119 0.0328
Loa Loa (eye worm) hypothetical protein 0.0051 0.0385 0.0625
Loa Loa (eye worm) hypothetical protein 0.0016 0.0029 0.0047
Schistosoma mansoni retinoid-x-receptor (RXR) 0.0021 0.0076 0.0082
Echinococcus multilocularis transfer RNA-Gly 0.0036 0.0234 0.0234
Trypanosoma cruzi 2,4-dienoyl-coa reductase fadh1, putative 0.0086 0.0743 0.0879
Loa Loa (eye worm) hypothetical protein 0.0042 0.0296 0.0481
Mycobacterium tuberculosis Putative ferredoxin reductase 0.0193 0.1837 0.2946
Schistosoma mansoni glutamate receptor AMPA 0.0167 0.1574 0.171
Echinococcus granulosus fmrfamide receptor 0.0135 0.1244 0.1244
Brugia malayi putative neuropeptide receptor NPR1 0.0135 0.1244 0.2018
Echinococcus granulosus rhodopsin orphan GPCR 0.0135 0.1244 0.1244
Loa Loa (eye worm) tubulin beta-4 chain 0.0026 0.0131 0.0213
Trypanosoma brucei tyrosyl-DNA Phosphodiesterase (Tdp1), putative 0.0068 0.056 0.0657
Schistosoma mansoni neuropeptide receptor 0.0135 0.1244 0.1352
Echinococcus granulosus tyrosine protein kinase Fyn 0.004 0.0269 0.0269
Echinococcus granulosus COUP TF:Svp nuclear hormone receptor 0.0021 0.0076 0.0076
Toxoplasma gondii hypothetical protein 0.0042 0.0296 0.0435
Schistosoma mansoni transient receptor potential channel 0.0036 0.0234 0.0254
Echinococcus multilocularis ecdysone induced protein 78C 0.0021 0.0076 0.0076
Echinococcus multilocularis histone lysine N methyltransferase SETMAR 0.0031 0.0185 0.0185
Schistosoma mansoni calcium channel voltage-dependent p/q type alpha 1a-related 0.0036 0.0234 0.0254
Echinococcus multilocularis transient receptor potential cation channel 0.0036 0.0234 0.0234
Toxoplasma gondii beta tubulin 0.0026 0.0131 0.0166
Treponema pallidum 4'-phosphopantetheinyl transferase 0.0024 0.011 0.0155
Echinococcus granulosus calmodulin 0.0025 0.0121 0.0121
Schistosoma mansoni cyclic-nucleotide-gated cation channel 0.0041 0.0285 0.031
Onchocerca volvulus 0.003 0.0166 0.0386
Trichomonas vaginalis glucosylceramidase, putative 0.0266 0.2593 0.8149
Brugia malayi hypothetical protein 0.0135 0.1244 0.2018
Schistosoma mansoni norepinephrine/norepinephrine transporter 0.0249 0.2419 0.2628
Plasmodium falciparum holo-[acyl-carrier-protein] synthase, putative 0.0024 0.011 0.0131
Trypanosoma cruzi NADH dehydrogenase, putative 0.0086 0.0743 0.0879
Giardia lamblia Beta tubulin 0.0026 0.0131 0.0225
Trichomonas vaginalis glucosylceramidase, putative 0.0266 0.2593 0.8149
Wolbachia endosymbiont of Brugia malayi DNA gyrase subunit A 0.0031 0.018 0.0382
Schistosoma mansoni 60S ribosomal protein L21 0.004 0.0269 0.0292
Trichomonas vaginalis disulfide oxidoreductase, putative 0.0086 0.0743 0.23
Mycobacterium ulcerans aerobic-type carbon monoxide dehydrogenase subunit CoxM_2 0.006 0.0481 0.1346
Echinococcus multilocularis cpg binding protein 0.0031 0.0183 0.0183
Onchocerca volvulus 0.0025 0.0121 0.0194
Schistosoma mansoni voltage-gated potassium channel 0.0075 0.0634 0.0688
Echinococcus multilocularis isocitrate dehydrogenase 2 (NADP+) 0.0016 0.0029 0.0029
Onchocerca volvulus 0.0036 0.0234 0.0675
Schistosoma mansoni transient receptor potential cation channel subfamily m member 0.0036 0.0234 0.0254
Schistosoma mansoni voltage-gated potassium channel 0.0036 0.0234 0.0254
Loa Loa (eye worm) TK protein kinase 0.0032 0.0191 0.0309
Leishmania major calmodulin, putative 0.0025 0.0121 0.0121
Trichomonas vaginalis PIKK family atypical protein kinase 0.0037 0.024 0.0713
Echinococcus granulosus rhodopsin orphan GPCR 0.0135 0.1244 0.1244
Loa Loa (eye worm) voltage-dependent calcium channel 0.0054 0.0421 0.0682
Loa Loa (eye worm) nuclear hormone receptor family member nhr-41 0.0021 0.0076 0.0123
Echinococcus multilocularis rhodopsin orphan GPCR 0.0135 0.1244 0.1244
Echinococcus multilocularis Tubulin beta 2C chain 0.0026 0.0131 0.0131
Echinococcus granulosus peregrin 0.003 0.0171 0.0171
Echinococcus multilocularis neuropeptide Y receptor 0.0135 0.1244 0.1244
Brugia malayi Nuclear hormone receptor family member nhr-49 0.0021 0.0076 0.0123
Mycobacterium ulcerans NADPH:adrenodoxin oxidoreductase FprB 0.0086 0.0743 0.2186
Brugia malayi glutamate synthase 0.0086 0.0743 0.1204
Loa Loa (eye worm) TOPoisomerase family member 0.0144 0.134 0.2174
Trichomonas vaginalis tubulin beta chain, putative 0.0026 0.0131 0.0368
Loa Loa (eye worm) G-protein coupled receptor 0.0135 0.1244 0.2018
Echinococcus multilocularis lamin dm0 0.0028 0.0148 0.0148
Echinococcus granulosus hypothetical protein 0.0036 0.0234 0.0234
Echinococcus multilocularis jun protein 0.0087 0.075 0.075
Trypanosoma brucei Voltage-dependent calcium channel subunit, putative 0.0094 0.0826 0.0981
Echinococcus multilocularis voltage dependent calcium channel type d subunit 0.0133 0.1224 0.1224
Echinococcus granulosus alpha 1A adrenergic receptor 0.0135 0.1244 0.1244
Brugia malayi hypothetical protein 0.0135 0.1244 0.2018
Loa Loa (eye worm) hypothetical protein 0.0023 0.0103 0.0168
Leishmania major beta tubulin 0.0026 0.0131 0.0134
Echinococcus multilocularis somatostatin receptor 0.0135 0.1244 0.1244
Schistosoma mansoni cellular tumor antigen P53 0.0051 0.0385 0.0418
Plasmodium falciparum glutathione reductase 0.0323 0.3179 0.5132
Loa Loa (eye worm) hypothetical protein 0.0135 0.1244 0.2018
Brugia malayi Tubulin beta-1 chain 0.0026 0.0131 0.0213
Echinococcus granulosus voltage gated potassium channel 0.0036 0.0234 0.0234
Echinococcus multilocularis glutamate receptor 2 0.019 0.1815 0.1815
Echinococcus granulosus voltage dependent calcium channel type d subunit|voltage dependent calcium channel alpha 1 0.0133 0.1224 0.1224
Echinococcus granulosus biogenic amine 5HT receptor 0.0911 0.9204 0.9204
Leishmania major beta tubulin 0.0026 0.0131 0.0134
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0135 0.1244 0.1352
Schistosoma mansoni transient receptor potential cation channel subfamily m member 0.0036 0.0234 0.0254
Trichomonas vaginalis glucosylceramidase, putative 0.0184 0.175 0.5486
Schistosoma mansoni calmodulin 0.0025 0.0121 0.0132
Entamoeba histolytica hypothetical protein 0.0024 0.011 0.0167
Onchocerca volvulus 0.0043 0.0305 0.098
Brugia malayi olfactory channel protein osm-9 0.0036 0.0236 0.0383
Onchocerca volvulus 0.0135 0.1244 0.4987
Brugia malayi Sodium:neurotransmitter symporter family protein 0.0042 0.0296 0.048
Brugia malayi follicle stimulating hormone receptor 0.0135 0.1244 0.2018
Echinococcus multilocularis G-protein coupled receptor, putative 0.0135 0.1244 0.1244
Brugia malayi Iron-sulfur cluster assembly accessory protein 0.005 0.0372 0.0604
Leishmania major apurinic/apyrimidinic endonuclease-redox protein 0.0019 0.0061 0.0048
Giardia lamblia Kinase, CMGC MAPK 0.0053 0.0401 0.109
Schistosoma mansoni myosin xvIII 0.0135 0.1244 0.1352
Leishmania major beta tubulin 0.0026 0.0131 0.0134
Trypanosoma cruzi cytochrome P450, putative 0.002 0.0067 0.0056
Echinococcus multilocularis neuropeptide receptor A26 0.0609 0.6109 0.6109
Onchocerca volvulus Transient receptor potential cation channel trpm homolog 0.0036 0.0234 0.0675
Echinococcus granulosus potassium voltage gated channel subfamily D 0.0036 0.0234 0.0234
Onchocerca volvulus 0.0135 0.1244 0.4987
Loa Loa (eye worm) hypothetical protein 0.0023 0.0103 0.0168
Trichomonas vaginalis glucosylceramidase, putative 0.0175 0.1654 0.5181
Schistosoma mansoni lipoxygenase 0.0178 0.1693 0.1839
Trypanosoma brucei dihydrolipoamide dehydrogenase, point mutation 0.0634 0.6369 0.7742
Trichomonas vaginalis tubulin alpha chain, putative 0.0026 0.0131 0.0368
Trichomonas vaginalis conserved hypothetical protein 0.0029 0.0155 0.0442
Echinococcus granulosus FKBP12 rapamycin complex associated protein 0.0046 0.0338 0.0338
Echinococcus multilocularis hepatocyte nuclear factor 4 alpha 0.0021 0.0076 0.0076
Plasmodium falciparum dihydrolipoyl dehydrogenase, mitochondrial 0.0323 0.3179 0.5132
Loa Loa (eye worm) G-protein-linked acetylcholine receptor protein 2 0.0135 0.1244 0.2018
Echinococcus granulosus Polycystic kidney disease protein 0.0041 0.0279 0.0279
Echinococcus multilocularis metabotropic glutamate receptor 2 0.0023 0.0103 0.0103
Loa Loa (eye worm) hypothetical protein 0.0135 0.1244 0.2018
Loa Loa (eye worm) hypothetical protein 0.0135 0.1244 0.2018
Loa Loa (eye worm) unidentified vitellogenin-linked transcript protein 6 0.0135 0.1244 0.2018
Plasmodium vivax multidomain scavenger receptor, putative 0.0041 0.0279 0.0407
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0021 0.0076 0.0076
Schistosoma mansoni cyclic-nucleotide-gated cation channel 0.0036 0.0234 0.0254
Brugia malayi calmodulin 0.0025 0.0121 0.0196
Echinococcus granulosus tm gpcr rhodopsin 0.0668 0.6717 0.6717
Echinococcus multilocularis tyrosine protein kinase Src64B 0.004 0.0269 0.0269
Echinococcus granulosus epidermal growth factor receptor 0.0155 0.145 0.145
Loa Loa (eye worm) hypothetical protein 0.0023 0.0103 0.0168
Loa Loa (eye worm) CMGC/MAPK/ERK1 protein kinase 0.0053 0.0401 0.0651
Echinococcus multilocularis glutamate receptor ionotropic kainate 0.0071 0.0594 0.0594
Plasmodium vivax glutathione reductase, putative 0.0615 0.6166 1
Brugia malayi Phosphatidylinositol 3- and 4-kinase family protein 0.0016 0.0022 0.0035
Echinococcus multilocularis pyridine nucleotide disulfide oxidoreductase 0.0086 0.0743 0.0743
Echinococcus multilocularis potassium:sodium hyperpolarization activated 0.0041 0.0285 0.0285
Toxoplasma gondii NADPH-glutathione reductase 0.0323 0.3179 0.5132
Brugia malayi Tyrosyl-DNA phosphodiesterase family protein 0.0068 0.056 0.0908
Trypanosoma brucei trypanothione reductase 0.0615 0.6166 0.7493
Toxoplasma gondii Sodium:neurotransmitter symporter family protein 0.0042 0.0296 0.0435
Schistosoma mansoni glutamate synthase 0.0086 0.0743 0.0807
Leishmania major calmodulin, putative 0.0025 0.0121 0.0121
Schistosoma mansoni glutamate receptor kainate 0.0167 0.1574 0.171
Brugia malayi cation channel family protein 0.0036 0.0234 0.0378
Mycobacterium tuberculosis Probable endonuclease IV End (endodeoxyribonuclease IV) (apurinase) 0.0079 0.0673 0.1048
Echinococcus granulosus transient receptor potential cation channel 0.0036 0.0234 0.0234
Loa Loa (eye worm) doublecortin family protein 0.0041 0.0279 0.0453
Trichomonas vaginalis dihydropyrimidine dehydrogenase, putative 0.0086 0.0743 0.23
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0018 0.005 0.0054
Leishmania major hypothetical protein, conserved 0.0086 0.0743 0.0879
Plasmodium vivax DNA gyrase subunit A, putative 0.0031 0.018 0.0246
Plasmodium falciparum dihydrolipoyl dehydrogenase, apicoplast 0.0323 0.3179 0.5132
Trypanosoma brucei mitogen activated protein kinase 4, putative 0.0053 0.0401 0.0463
Echinococcus granulosus neuropeptides capa receptor 0.0135 0.1244 0.1244
Schistosoma mansoni adenoreceptor 0.0135 0.1244 0.1352
Trypanosoma brucei beta tubulin 0.0026 0.0131 0.0134
Echinococcus granulosus ecdysone induced protein 78C 0.0021 0.0076 0.0076
Trichomonas vaginalis glucosylceramidase, putative 0.0266 0.2593 0.8149
Echinococcus granulosus potassium voltage gated channel protein 0.0036 0.0234 0.0234
Onchocerca volvulus Calmodulin homolog 0.0025 0.0121 0.0195
Brugia malayi Pre-SET motif family protein 0.0215 0.207 0.3356
Trypanosoma cruzi tyrosyl-DNA Phosphodiesterase (Tdp1), putative 0.0068 0.056 0.0657
Treponema pallidum amino acid ABC transporter, periplasmic binding protein (hisJ) 0.0039 0.0262 0.0644
Brugia malayi nuclear receptor NHR-88 0.0021 0.0076 0.0123
Loa Loa (eye worm) hypothetical protein 0.038 0.3756 0.6091
Echinococcus granulosus tyrosine protein kinase Src42A 0.0034 0.021 0.021
Loa Loa (eye worm) nuclear hormone receptor family member nhr-40 0.0021 0.0076 0.0123
Loa Loa (eye worm) glutamate receptor 0.0023 0.0103 0.0168
Loa Loa (eye worm) hypothetical protein 0.0021 0.0076 0.0123
Trichomonas vaginalis PIKK family atypical protein kinase 0.0028 0.0146 0.0416
Echinococcus multilocularis FKBP12 rapamycin complex associated protein 0.0046 0.0338 0.0338
Trypanosoma cruzi ferric reductase transmembrane protein, putative 0.0035 0.0223 0.0245
Leishmania major hypothetical protein, conserved 0.0035 0.0225 0.0248
Echinococcus granulosus sex peptide receptor 0.0135 0.1244 0.1244
Loa Loa (eye worm) hypothetical protein 0.0021 0.0076 0.0122
Loa Loa (eye worm) hypothetical protein 0.0135 0.1244 0.2018
Trypanosoma cruzi Voltage-dependent calcium channel subunit, putative 0.0094 0.0826 0.0981
Schistosoma mansoni voltage-gated potassium channel 0.0036 0.0234 0.0254
Schistosoma mansoni peptide (allatostatin)-like receptor 0.0135 0.1244 0.1352
Echinococcus multilocularis Tubulin beta 2C chain 0.0026 0.0131 0.0131
Loa Loa (eye worm) tubulin beta-1 chain 0.0026 0.0131 0.0213
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0018 0.0052 0.0117
Echinococcus multilocularis rhodopsin orphan GPCR 0.0135 0.1244 0.1244
Loa Loa (eye worm) hypothetical protein 0.0562 0.5622 0.9119
Brugia malayi Nuclear hormone receptor-like 1 0.0021 0.0076 0.0123
Echinococcus granulosus Ribosomal protein S1 RNA binding domain 0.0071 0.0594 0.0594
Echinococcus multilocularis jumonji domain containing protein 0.0042 0.0291 0.0291
Mycobacterium tuberculosis Inositol-1-monophosphatase SuhB 0.0034 0.0212 0.0298
Loa Loa (eye worm) hypothetical protein 0.0386 0.382 0.6195
Loa Loa (eye worm) hypothetical protein 0.0135 0.1244 0.2018
Giardia lamblia Thioredoxin reductase 0.0086 0.0743 0.2186
Trypanosoma cruzi beta tubulin, putative 0.0026 0.0131 0.0134
Echinococcus granulosus glutamate receptor NMDA 0.0081 0.0696 0.0696
Echinococcus granulosus neuropeptide Y receptor 0.0135 0.1244 0.1244
Trypanosoma brucei C-8 sterol isomerase, putative 0.038 0.3756 0.4554
Trypanosoma cruzi mitogen activated protein kinase 2, putative 0.0053 0.0401 0.0463
Loa Loa (eye worm) hypothetical protein 0.0135 0.1244 0.2018
Loa Loa (eye worm) tubulin beta-2A chain 0.0026 0.0131 0.0213
Schistosoma mansoni voltage-dependent calcium channel 0.0036 0.0234 0.0254
Brugia malayi nuclear hormone receptor 0.0021 0.0076 0.0123
Echinococcus granulosus potassium voltage gated channel protein 0.0036 0.0234 0.0234
Trypanosoma cruzi ERV/ALR sulfhydryl oxidase domain-containing protein 0.0035 0.0225 0.0248
Schistosoma mansoni steroid hormone receptor ad4bp 0.0021 0.0076 0.0082
Loa Loa (eye worm) follicle stimulating hormone receptor 0.0135 0.1244 0.2018
Echinococcus multilocularis cyclic nucleotide gated cation channel 0.0041 0.0285 0.0285
Schistosoma mansoni cyclic-nucleotide-gated cation channel 0.0041 0.0285 0.031
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0135 0.1244 0.1352
Echinococcus multilocularis peptide (allatostatin:somatostatin) 0.0135 0.1244 0.1244
Loa Loa (eye worm) CXXC zinc finger family protein 0.003 0.0166 0.0269
Echinococcus granulosus g protein coupled receptor 0.0135 0.1244 0.1244
Trichomonas vaginalis calmodulin, putative 0.0025 0.0121 0.0337
Brugia malayi Voltage-gated potassium channel, Shaw-family (KCNC, Kv3-like) alpha-subunit 0.0036 0.0234 0.0378
Schistosoma mansoni hypothetical protein 0.003 0.0171 0.0185
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0707 0.7112 0.8647
Mycobacterium tuberculosis holo-[acyl-carrier protein] synthase AcpS (holo-ACP synthase) (CoA:APO-[ACP]pantetheinephosphotransferase) (CoA:APO-[acyl-carrie 0.0024 0.011 0.0131
Loa Loa (eye worm) cytochrome P450 family protein 0.002 0.0067 0.0109
Schistosoma mansoni hypothetical protein 0.0035 0.0223 0.0242
Echinococcus granulosus somatostatin receptor 0.0135 0.1244 0.1244
Echinococcus granulosus Basic leucine zipper bZIP transcription factor 0.0087 0.075 0.075
Loa Loa (eye worm) cyclic-nucleotide gated cation channel 0.0041 0.0285 0.0462
Echinococcus granulosus Tubulin beta 2C chain 0.0026 0.0131 0.0131
Plasmodium falciparum apurinic/apyrimidinic endonuclease Apn1, putative 0.0079 0.0673 0.1048
Loa Loa (eye worm) hypothetical protein 0.0021 0.0076 0.0123
Loa Loa (eye worm) exodeoxyribonuclease III family protein 0.0019 0.0061 0.0099
Loa Loa (eye worm) transcription factor SMAD2 0.0123 0.1125 0.1824
Schistosoma mansoni survival motor neuron protein 0.005 0.0372 0.0404
Loa Loa (eye worm) hypothetical protein 0.0036 0.0234 0.0379
Chlamydia trachomatis DNA gyrase subunit A 0.0031 0.018 0.023
Schistosoma mansoni voltage-gated potassium channel 0.0045 0.0321 0.0348
Echinococcus multilocularis calmodulin 0.0025 0.0121 0.0121
Echinococcus granulosus voltage gated hydrogen channel 1 0.0036 0.0234 0.0234
Echinococcus multilocularis Ribosomal protein S1, RNA binding domain 0.0071 0.0594 0.0594
Echinococcus granulosus tyrosine protein kinase Lyn 0.004 0.0274 0.0274
Echinococcus multilocularis sodium leak channel non selective protein 0.0036 0.0234 0.0234
Mycobacterium tuberculosis NADPH:adrenodoxin oxidoreductase FprA (NADPH-ferredoxin reductase) 0.0086 0.0743 0.1162
Echinococcus multilocularis tyrosine protein kinase Fyn 0.004 0.0269 0.0269
Trichomonas vaginalis chromobox protein, putative 0.0072 0.0599 0.1846
Trypanosoma cruzi mitochondrial DNA topoisomerase II, putative 0.0162 0.1521 0.1829
Echinococcus multilocularis tyrosine protein kinase lyn tyrosine protein kinase blk 0.004 0.0269 0.0269
Loa Loa (eye worm) calcium channel 0.0133 0.1224 0.1985
Schistosoma mansoni tyrosine kinase 0.0082 0.0701 0.0761
Brugia malayi G-protein coupled receptor 0.0135 0.1244 0.2018
Echinococcus granulosus neuropeptide receptor A26 0.0609 0.6109 0.6109
Trypanosoma cruzi NADH dehydrogenase, putative 0.0086 0.0743 0.0879
Brugia malayi Cytochrome P450 family protein 0.002 0.0067 0.0109
Echinococcus granulosus g protein linked acetylcholine receptor gar 2a 0.0135 0.1244 0.1244
Loa Loa (eye worm) nuclear hormone receptor family member nhr-31 0.0021 0.0076 0.0123
Leishmania major beta tubulin 0.0026 0.0131 0.0134
Echinococcus granulosus shaker cognate 0.0036 0.0234 0.0234
Leishmania major 2,4-dienoyl-coa reductase-like protein 0.0086 0.0743 0.0879
Brugia malayi Voltage-gated calcium channel, alpha subunit 0.0036 0.0234 0.0378
Echinococcus multilocularis short transient receptor potential channel 6 0.0036 0.0236 0.0236
Mycobacterium ulcerans NADH dehydrogenase Ndh 0.0086 0.0743 0.2186
Echinococcus multilocularis phosphatidylinositol 3 and 4 kinase 0.0016 0.0022 0.0022
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0018 0.0052 0.0117
Trypanosoma brucei Phosphatidylinositol 3-kinase tor1 0.0046 0.0338 0.0385
Mycobacterium leprae Probable NADPH:adrenodoxin oxidoreductase FprA (NADPH-FERREDOXIN REDUCTASE) 0.0086 0.0743 0.1589
Brugia malayi Thioredoxin reductase 0.0615 0.6166 1
Mycobacterium tuberculosis Probable carbon monoxyde dehydrogenase (small chain) 0.0034 0.0212 0.0298
Schistosoma mansoni Tr4/Tr2 (homologue) 0.0021 0.0076 0.0082
Echinococcus granulosus dihydrolipoamide dehydrogenase 0.0323 0.3179 0.3179
Echinococcus multilocularis transient receptor potential gamma protein 0.0036 0.0234 0.0234
Onchocerca volvulus 0.0077 0.0651 0.2457
Schistosoma mansoni phosphatidylinositol 3-and 4-kinase 0.0016 0.0022 0.0023
Echinococcus multilocularis Tubulin beta 2C chain 0.0026 0.0131 0.0131
Brugia malayi SRC-1 0.004 0.0269 0.0437
Echinococcus granulosus cyclic nucleotide gated cation channel 0.0041 0.0285 0.0285
Brugia malayi Voltage-gated potassium channel, Shaw-family (KCNC, Kv3-like) alpha-subunit. C. elegans egl-36 ortholog 0.0036 0.0234 0.0378
Onchocerca volvulus 0.0135 0.1244 0.4987
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0668 0.6717 0.6717
Trichomonas vaginalis tubulin epsilon chain, putative 0.0026 0.0131 0.0368
Brugia malayi beta-tubulin, identical 0.0026 0.0131 0.0213
Echinococcus multilocularis Basic leucine zipper (bZIP) transcription factor 0.0087 0.075 0.075
Echinococcus granulosus NADP dependent isocitrate dehydrogenase 0.0016 0.0029 0.0029
Entamoeba histolytica dihydropyrimidine dehydrogenase, putative 0.0086 0.0743 0.2357
Echinococcus multilocularis short transient receptor potential channel 6 0.0036 0.0234 0.0234
Loa Loa (eye worm) hypothetical protein 0.0041 0.0279 0.0453
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0301 0.2953 0.9285
Schistosoma mansoni tyrosine kinase 0.004 0.0269 0.0292
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.0036 0.0234 0.0333
Brugia malayi putative neuropeptide receptor 0.0135 0.1244 0.2018
Brugia malayi ORL1-like opioid receptor 0.0135 0.1244 0.2018
Trichomonas vaginalis PIKK family atypical protein kinase 0.0034 0.0216 0.0635
Onchocerca volvulus Protein ultraspiracle homolog 0.0021 0.0076 0.0003
Loa Loa (eye worm) hypothetical protein 0.0386 0.382 0.6195
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0021 0.0076 0.0076
Toxoplasma gondii ATPase/histidine kinase/DNA gyrase B/HSP90 domain-containing protein 0.0084 0.0724 0.1132
Onchocerca volvulus Bile acid receptor homolog 0.0021 0.0076 0.0003
Trichomonas vaginalis glutamate synthase, putative 0.0086 0.0743 0.23
Echinococcus multilocularis CalModulin family member (cmd 1) 0.0025 0.0121 0.0121
Schistosoma mansoni RAR-like nuclear receptor 0.0021 0.0076 0.0082
Schistosoma mansoni hypothetical protein 0.0016 0.0029 0.0031
Leishmania major hypothetical protein, conserved 0.0086 0.0743 0.0879
Echinococcus multilocularis voltage dependent calcium channel 0.0133 0.1224 0.1224
Loa Loa (eye worm) hypothetical protein 0.0219 0.211 0.3423
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0815 0.8221 1
Trichomonas vaginalis glutathione reductase, putative 0.0323 0.3179 1
Trichomonas vaginalis PIKK family atypical protein kinase 0.0025 0.0119 0.0328
Wolbachia endosymbiont of Brugia malayi NADPH-dependent glutamate synthase beta chain 0.0086 0.0743 0.2186
Echinococcus granulosus insulin growth factor 1 receptor beta 0.005 0.0377 0.0377
Echinococcus granulosus G protein coupled receptor 139 0.0135 0.1244 0.1244
Echinococcus granulosus glutamate receptor ionotropic kainate 3 0.0071 0.0594 0.0594
Echinococcus granulosus pyroglutamylated rfamide peptide receptor 0.0135 0.1244 0.1244
Schistosoma mansoni tubulin subunit beta 0.0026 0.0131 0.0142
Brugia malayi Voltage-gated potassium channel, Shab-family (KCNB, Kv2-like) alpha-subunit 0.0036 0.0234 0.0378
Echinococcus granulosus thioredoxin glutathione reductase 0.0615 0.6166 0.6166
Toxoplasma gondii pyruvate dehydrogenase complex subunit PDH-E3II 0.0323 0.3179 0.5132
Onchocerca volvulus Dual oxidase homolog 0.0075 0.0631 0.2369
Echinococcus granulosus calmodulin 0.0025 0.0121 0.0121
Echinococcus multilocularis neuropeptides capa receptor 0.0135 0.1244 0.1244
Echinococcus granulosus voltage gated sodium channel Nav1 alpha subunit 0.0478 0.4769 0.4769
Mycobacterium tuberculosis Probable NADH dehydrogenase Ndh 0.0193 0.1837 0.2946
Trypanosoma cruzi Phosphatidylinositol 3-kinase tor2 0.0046 0.0338 0.0385
Trypanosoma brucei isocitrate dehydrogenase [NADP], mitochondrial precursor, putative 0.0016 0.0029 0.0009
Loa Loa (eye worm) BEN-1 protein 0.0026 0.0131 0.0213
Toxoplasma gondii pyridine nucleotide-disulfide oxidoreductase domain-containing protein 0.0086 0.0743 0.1162
Brugia malayi hypothetical protein 0.0135 0.1244 0.2018
Leishmania major tyrosyl-DNA phosphodiesterase 1 0.0068 0.056 0.0657
Echinococcus multilocularis calmodulin 0.0025 0.0121 0.0121
Loa Loa (eye worm) ion channel NompC 0.0036 0.0234 0.0379
Trichomonas vaginalis PIKK family atypical protein kinase 0.0016 0.0022 0.0022
Chlamydia trachomatis thioredoxin reductase 0.0086 0.0743 0.2063
Echinococcus multilocularis survival motor neuron protein 1 0.0244 0.2363 0.2363
Brugia malayi Serotonin receptor 0.0609 0.6109 0.9907
Loa Loa (eye worm) jmjC domain-containing protein 0.0038 0.0253 0.041
Mycobacterium tuberculosis Probable fructose-bisphosphate aldolase Fba 0.0147 0.1372 0.2188
Mycobacterium ulcerans hypothetical protein 0.0021 0.0076 0.0046
Brugia malayi hypothetical protein 0.0244 0.2363 0.3832
Brugia malayi Serotonin receptor 0.0135 0.1244 0.2018
Loa Loa (eye worm) thioredoxin reductase 0.0615 0.6166 1
Brugia malayi Glutamate receptor 1 precursor 0.0167 0.1574 0.2553
Loa Loa (eye worm) hypothetical protein 0.0059 0.0464 0.0752
Mycobacterium leprae DIHYDROLIPOAMIDE DEHYDROGENASE LPD (LIPOAMIDE REDUCTASE (NADH)) (LIPOYL DEHYDROGENASE) (DIHYDROLIPOYL DEHYDROGENASE) (DIAPHORASE 0.043 0.4273 1
Schistosoma mansoni biogenic amine receptor 0.0135 0.1244 0.1352
Echinococcus granulosus metabotropic glutamate receptor 5 0.0023 0.0103 0.0103
Trichomonas vaginalis PIKK family atypical protein kinase 0.0027 0.0144 0.0407
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0301 0.2953 0.9285
Echinococcus multilocularis uncharacterized sodium dependent transporter 0.0042 0.0296 0.0296
Plasmodium falciparum thioredoxin reductase 0.0615 0.6166 1
Echinococcus multilocularis Glutamate receptor, ionotropic kainate 3 0.011 0.0994 0.0994
Echinococcus granulosus proto oncogene tyrosine protein kinase LCK 0.004 0.0269 0.0269
Loa Loa (eye worm) metabotropic GABA-B receptor subtype 2 0.0023 0.0103 0.0168
Echinococcus multilocularis insulin receptor 0.005 0.0377 0.0377
Trypanosoma brucei inositol 1,4,5-trisphosphate receptor 0.0036 0.0234 0.0258
Loa Loa (eye worm) 5-hydroxytryptamine 2C receptor 0.0135 0.1244 0.2018
Schistosoma mansoni chromobox protein 0.0072 0.0599 0.0651
Giardia lamblia Fructose-bisphosphate aldolase 0.0301 0.2953 0.9275
Toxoplasma gondii Sodium:neurotransmitter symporter family protein 0.0042 0.0296 0.0435
Mycobacterium leprae Probable NADH-dependent glutamate synthase (small subunit) GltD (L-glutamate synthase) (L-glutamate synthetase) (NADH-glutamate 0.0086 0.0743 0.1589
Echinococcus granulosus hyperpolarization activated cyclic 0.0041 0.0285 0.0285
Loa Loa (eye worm) hypothetical protein 0.0135 0.1244 0.2018
Trichomonas vaginalis PIKK family atypical protein kinase 0.0016 0.0022 0.0022
Toxoplasma gondii 4'-phosphopantetheinyl transferase domain-containing protein 0.0024 0.011 0.0131
Brugia malayi hypothetical protein 0.0135 0.1244 0.2018
Echinococcus granulosus potassium voltage gated channel subfamily D 0.0036 0.0234 0.0234
Schistosoma mansoni voltage-gated potassium channel 0.0036 0.0234 0.0254
Echinococcus multilocularis potassium voltage gated channel protein 0.0036 0.0234 0.0234
Schistosoma mansoni amine GPCR 0.0135 0.1244 0.1352
Loa Loa (eye worm) beta-tubulin 0.0026 0.0131 0.0213
Trichomonas vaginalis PIKK family atypical protein kinase 0.0025 0.0119 0.0329
Loa Loa (eye worm) TYRA-2 protein 0.0135 0.1244 0.2018
Brugia malayi Pyridine nucleotide-disulphide oxidoreductase family protein 0.0086 0.0743 0.1204
Schistosoma mansoni sodium/chloride dependent transporter 0.0042 0.0296 0.0322
Echinococcus granulosus glutamate NMDA receptor subunit 0.0338 0.3326 0.3326
Echinococcus granulosus glutamate synthase 0.0086 0.0743 0.0743
Brugia malayi alpha keto acid dehydrogenase complex, E3 component, lipoamide dehydrogenase 0.0238 0.2299 0.3728
Echinococcus granulosus transient receptor potential gamma protein 0.0036 0.0234 0.0234
Schistosoma mansoni hyperpolarization activated cyclic nucleotide-gated potassium channel 0.0041 0.0285 0.031
Echinococcus multilocularis neuropeptide s receptor 0.0609 0.6109 0.6109
Plasmodium falciparum ataxin-2 like protein, putative 0.0026 0.0129 0.0162
Brugia malayi Inositol-1 0.0038 0.0253 0.041
Loa Loa (eye worm) hypothetical protein 0.0135 0.1244 0.2018
Loa Loa (eye worm) RGC/RGC protein kinase 0.0029 0.0159 0.0257
Brugia malayi hypothetical protein 0.0041 0.0279 0.0453
Loa Loa (eye worm) voltage-gated calcium channel 0.0036 0.0234 0.0379
Mycobacterium ulcerans DNA gyrase subunit A 0.0031 0.018 0.0382
Brugia malayi Cyclic-nucleotide gated cation channel 0.0041 0.0285 0.0462
Loa Loa (eye worm) G-protein coupled receptor 0.0135 0.1244 0.2018
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0135 0.1244 0.1244
Onchocerca volvulus 0.0245 0.2376 0.9817
Echinococcus granulosus tubulin beta 1 chain 0.0026 0.0131 0.0131
Schistosoma mansoni glutamate synthase 0.0086 0.0743 0.0807
Onchocerca volvulus Adenylate cyclase type 3 homolog 0.0223 0.2146 0.8833
Loa Loa (eye worm) hypothetical protein 0.0036 0.0234 0.0379
Echinococcus granulosus neuropeptide s receptor 0.0609 0.6109 0.6109
Brugia malayi Voltage-gated potassium channel, EAG (KCNH1)-related. C. elegans egl-2 ortholog 0.0045 0.0321 0.052
Treponema pallidum DNA gyrase, subunit A (gyrA) 0.0031 0.018 0.0382
Loa Loa (eye worm) hypothetical protein 0.0079 0.0673 0.1091
Echinococcus granulosus potassium voltage gated channel subfamily H 0.0072 0.0598 0.0598
Treponema pallidum DNA gyrase, subunit B (gyrB) 0.0084 0.0724 0.2127
Schistosoma mansoni high voltage-activated calcium channel Cav2A 0.0133 0.1224 0.133
Loa Loa (eye worm) hypothetical protein 0.0562 0.5622 0.9119
Echinococcus multilocularis g-protein coupled receptor 0.0135 0.1244 0.1244
Brugia malayi aminoadipate-semialdehyde dehydrogenase-phosphopantetheinyl transferase 0.0086 0.0741 0.1202
Chlamydia trachomatis dihydrolipoyl dehydrogenase 0.0323 0.3179 1
Echinococcus multilocularis tyrosine protein kinase Src42A 0.0034 0.021 0.021
Brugia malayi G protein-coupled receptor 0.0135 0.1244 0.2018
Schistosoma mansoni metabotropic glutamate receptor 0.0023 0.0103 0.0112
Mycobacterium tuberculosis Probable NADH-dependent glutamate synthase (small subunit) GltD (L-glutamate synthase) (L-glutamate synthetase) (NADH-glutamate 0.0086 0.0743 0.1162
Schistosoma mansoni inositol monophosphatase 0.0038 0.0253 0.0275
Onchocerca volvulus 0.0249 0.2419 1
Schistosoma mansoni norepinephrine/norepinephrine transporter 0.0042 0.0296 0.0322
Brugia malayi hypothetical protein 0.0023 0.0103 0.0167
Plasmodium vivax tubulin beta chain, putative 0.0026 0.0131 0.0166
Echinococcus multilocularis glutamate receptor NMDA 0.0081 0.0696 0.0696
Echinococcus granulosus potassium:sodium hyperpolarization activated 0.0041 0.0285 0.0285
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0135 0.1244 0.1352
Schistosoma mansoni polycystin 1-related 0.0041 0.0279 0.0303
Loa Loa (eye worm) latrophilin receptor protein 2 0.0016 0.0029 0.0047
Entamoeba histolytica myo-inositol monophosphatase, putative 0.0038 0.0253 0.0663
Mycobacterium tuberculosis NAD(P)H quinone reductase LpdA 0.043 0.4273 0.6916
Entamoeba histolytica FKBP-rapamycin associated protein (FRAP), putative 0.0046 0.0338 0.0956
Echinococcus multilocularis rhodopsin orphan GPCR 0.0135 0.1244 0.1244
Loa Loa (eye worm) hypothetical protein 0.004 0.027 0.0438
Echinococcus multilocularis 7TM GPCR, rhodopsin 0.0135 0.1244 0.1244
Echinococcus multilocularis Nuclear hormone receptor family member nhr 41 0.0021 0.0076 0.0076
Echinococcus granulosus neuropeptide Y receptor 0.0135 0.1244 0.1244
Trichomonas vaginalis dihydroorotate dehydrogenase, putative 0.0086 0.0743 0.23
Echinococcus granulosus receptor type guanylyl cyclase 0.0029 0.0159 0.0159
Schistosoma mansoni transient receptor potential channel 0.0036 0.0234 0.0254
Onchocerca volvulus DNA topoisomerase 2 homolog 0.0097 0.0861 0.3352
Leishmania major beta tubulin 0.0026 0.0131 0.0134
Echinococcus granulosus lipoxygenase domain containing protein 0.0041 0.0279 0.0279
Echinococcus multilocularis calmodulin 0.0025 0.0121 0.0121
Mycobacterium leprae possible inositol monophosphatase SubH (IMPase) (inositol-1-phosphatase) (I-1-Pase ). 0.0034 0.0212 0.0325
Brugia malayi Heterochromatin protein 1 0.0072 0.0599 0.0971
Loa Loa (eye worm) hypothetical protein 0.0036 0.0234 0.0379
Loa Loa (eye worm) hypothetical protein 0.0036 0.0234 0.0379
Onchocerca volvulus Dopamine\/Ecdysteroid receptor homolog 0.0135 0.1244 0.4987
Trypanosoma brucei protein kinase, putative 0.0053 0.0401 0.0463
Loa Loa (eye worm) hypothetical protein 0.0086 0.0743 0.1205
Giardia lamblia PHD finger protein 15 0.003 0.0171 0.0351
Trichomonas vaginalis voltage and ligand gated potassium channel, putative 0.0041 0.0285 0.0854
Brugia malayi Voltage-gated calcium channel, P/Q-type, alpha subunit. C. elegans unc-2 ortholog 0.0036 0.0234 0.0378
Echinococcus multilocularis calmodulin 0.0025 0.0121 0.0121
Treponema pallidum sodium- and chloride- dependent transporter 0.0249 0.2419 0.7563
Loa Loa (eye worm) hypothetical protein 0.0032 0.0186 0.0302
Loa Loa (eye worm) isocitrate dehydrogenase 0.0016 0.0029 0.0048
Brugia malayi latrophilin 2 splice variant baaae 0.0035 0.0223 0.0361
Echinococcus multilocularis dihydrolipoamide dehydrogenase 0.0323 0.3179 0.3179
Mycobacterium ulcerans carbon monoxyde dehydrogenase large chain CoxL 0.0053 0.0405 0.1104
Entamoeba histolytica phosphatidylinositol3-kinaseTor2, putative 0.0046 0.0338 0.0956
Echinococcus multilocularis receptor type guanylyl cyclase 0.0029 0.0159 0.0159
Schistosoma mansoni opsin-like receptor 0.0135 0.1244 0.1352
Echinococcus multilocularis cadherin EGF LAG seven pass G type receptor 0.0016 0.0029 0.0029
Toxoplasma gondii inositol(myo)-1(or 4)-monophosphatase 2, putative 0.0038 0.0253 0.0364
Mycobacterium ulcerans fructose-bisphosphate aldolase 0.0147 0.1372 0.4204
Loa Loa (eye worm) hypothetical protein 0.0051 0.0389 0.0632
Mycobacterium ulcerans aerobic-type carbon monoxide dehydrogenase subunit CoxL_2 0.0084 0.0726 0.2133
Echinococcus granulosus sodium leak channel non selective protein 0.0036 0.0234 0.0234
Brugia malayi calcium-independent alpha-latrotoxin receptor 2, putative 0.0016 0.0029 0.0047
Entamoeba histolytica tubulin family protein 0.0026 0.0131 0.0243
Echinococcus multilocularis sodium channel protein 0.0478 0.4769 0.4769
Onchocerca volvulus 0.0029 0.0159 0.0354
Schistosoma mansoni serine/threonine protein kinase 0.0053 0.0401 0.0436
Echinococcus multilocularis epidermal growth factor receptor 0.0084 0.0721 0.0721
Echinococcus granulosus serotonin transporter 0.0249 0.2419 0.2419
Chlamydia trachomatis DNA gyrase subunit B 0.0084 0.0724 0.2002
Echinococcus granulosus pyridine nucleotide disulfide oxidoreductase 0.0086 0.0743 0.0743
Mycobacterium ulcerans hypothetical protein 0.0029 0.016 0.0317
Brugia malayi hypothetical protein 0.0135 0.1244 0.2018
Brugia malayi metabotropic glutamate receptor type 2 0.0023 0.0103 0.0167
Schistosoma mansoni photoreceptor-specific nuclear receptor related 0.0021 0.0076 0.0082
Schistosoma mansoni hypothetical protein 0.0071 0.0594 0.0645
Echinococcus multilocularis orexin receptor type 2 0.0135 0.1244 0.1244
Mycobacterium tuberculosis Probable exodeoxyribonuclease III protein XthA (exonuclease III) (EXO III) (AP endonuclease VI) 0.0019 0.0061 0.0052
Echinococcus multilocularis conserved hypothetical protein 0.0036 0.0234 0.0234
Echinococcus granulosus epidermal growth factor receptor 0.0084 0.0721 0.0721
Echinococcus multilocularis hyperpolarization activated cyclic 0.0041 0.0285 0.0285
Toxoplasma gondii non-proton pumping type-II NADH dehydrogenase I 0.0086 0.0743 0.1162
Plasmodium falciparum DNA gyrase subunit A 0.0031 0.018 0.0246
Echinococcus multilocularis COUP TF:Svp nuclear hormone receptor 0.0021 0.0076 0.0076
Leishmania major beta tubulin 0.0026 0.0131 0.0134
Giardia lamblia Calmodulin 0.0025 0.0121 0.0193
Loa Loa (eye worm) hypothetical protein 0.044 0.4371 0.709
Schistosoma mansoni ryanodine receptor related 0.0036 0.0234 0.0254
Leishmania major mitogen activated protein kinase, putative,map kinase, putative 0.0053 0.0401 0.0463
Plasmodium vivax dihydrolipoyl dehydrogenase, mitochondrial, putative 0.0323 0.3179 0.5132
Trypanosoma cruzi calmodulin 0.0025 0.0121 0.0121
Brugia malayi Pyridine nucleotide-disulphide oxidoreductase family protein 0.0086 0.0743 0.1204
Trypanosoma cruzi apurinic/apyrimidinic endonuclease, putative 0.0019 0.0061 0.0048
Echinococcus granulosus tyrosyl DNA phosphodiesterase 1 0.0068 0.056 0.056
Toxoplasma gondii hypothetical protein 0.0042 0.0296 0.0435
Brugia malayi Voltage-gated calcium channel, T-type, alpha subunit. C. elegans cca-1 ortholog 0.0036 0.0234 0.0378
Loa Loa (eye worm) Sodium:neurotransmitter symporter family protein 0.0042 0.0296 0.0481
Echinococcus multilocularis insulin growth factor 1 receptor beta 0.005 0.0377 0.0377
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0018 0.0052 0.0117

Activities

Activity type Activity value Assay description Source Reference
IC50 (binding) = 75 uM Compound was tested for the S3H domain binding using BIA core binding assay ChEMBL. 9873691

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
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External resources for this compound

No external resources registered for this compound

Bibliographic References

1 literature reference was collected for this gene.

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