Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Schistosoma mansoni | methionyl aminopeptidase 1 (M24 family) | 0.022 | 0.9 | 1 |
Echinococcus multilocularis | lamin dm0 | 0.0028 | 0.0567 | 0.0001 |
Loa Loa (eye worm) | initiation factor 2-associated protein | 0.0028 | 0.0566 | 0.0629 |
Schistosoma mansoni | lamin | 0.0028 | 0.0567 | 0.0001 |
Mycobacterium ulcerans | methionine aminopeptidase MapB | 0.022 | 0.9 | 1 |
Brugia malayi | RNA binding protein | 0.0063 | 0.2102 | 0.2336 |
Mycobacterium tuberculosis | Probable lipase LipE | 0.0036 | 0.0913 | 0.0395 |
Onchocerca volvulus | 0.0036 | 0.0913 | 0.0368 | |
Trichomonas vaginalis | neutral alpha-glucosidase ab precursor, putative | 0.0037 | 0.0972 | 0.0431 |
Trichomonas vaginalis | penicillin-binding protein, putative | 0.0036 | 0.0913 | 0.0368 |
Giardia lamblia | Methionine aminopeptidase | 0.0028 | 0.0566 | 0.5 |
Trypanosoma brucei | methionine aminopeptidase, putative | 0.022 | 0.9 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0028 | 0.0567 | 0.0629 |
Loa Loa (eye worm) | hypothetical protein | 0.0028 | 0.0566 | 0.0629 |
Schistosoma mansoni | family S12 unassigned peptidase (S12 family) | 0.0036 | 0.0913 | 0.0411 |
Mycobacterium ulcerans | aldehyde dehydrogenase | 0.0059 | 0.1954 | 0.1646 |
Mycobacterium ulcerans | aldehyde dehydrogenase | 0.0059 | 0.1954 | 0.1646 |
Loa Loa (eye worm) | hypothetical protein | 0.0036 | 0.0913 | 0.1014 |
Schistosoma mansoni | alpha-glucosidase | 0.0144 | 0.5654 | 0.6032 |
Echinococcus granulosus | aldehyde dehydrogenase mitochondrial | 0.0059 | 0.1954 | 0.1646 |
Mycobacterium tuberculosis | Probable conserved lipoprotein | 0.0036 | 0.0913 | 0.0395 |
Toxoplasma gondii | glycosyl hydrolase, family 31 protein | 0.0037 | 0.0972 | 0.0482 |
Schistosoma mansoni | tar DNA-binding protein | 0.0063 | 0.2102 | 0.1821 |
Trichomonas vaginalis | D-aminoacylase, putative | 0.0036 | 0.0913 | 0.0368 |
Onchocerca volvulus | 0.0028 | 0.0567 | 0.0001 | |
Echinococcus granulosus | 5'partial|histone lysine N methyltransferase SETDB2 | 0.0029 | 0.064 | 0.0087 |
Loa Loa (eye worm) | hypothetical protein | 0.0031 | 0.0689 | 0.0765 |
Brugia malayi | Pre-SET motif family protein | 0.0213 | 0.8707 | 0.9674 |
Trypanosoma cruzi | metallo- peptidase, Clan MG, Family M24 | 0.022 | 0.9 | 1 |
Schistosoma mansoni | aldehyde dehydrogenase | 0.0059 | 0.1954 | 0.1646 |
Schistosoma mansoni | intermediate filament proteins | 0.0028 | 0.0567 | 0.0001 |
Echinococcus granulosus | neutral alpha glucosidase AB | 0.0037 | 0.0972 | 0.0482 |
Echinococcus granulosus | methionyl aminopeptidase 1 M24 family | 0.022 | 0.9 | 1 |
Echinococcus multilocularis | geminin | 0.0168 | 0.6718 | 0.7294 |
Toxoplasma gondii | methionine aminopeptidase, type i, putative | 0.022 | 0.9 | 1 |
Schistosoma mansoni | alpha-glucosidase | 0.0144 | 0.5654 | 0.6032 |
Mycobacterium leprae | PROBABLE METHIONINE AMINOPEPTIDASE MAPB (MAP) (PEPTIDASE M) | 0.022 | 0.9 | 1 |
Mycobacterium ulcerans | esterase/lipase LipP | 0.0036 | 0.0913 | 0.0411 |
Brugia malayi | DNA-binding protein, 42 kDa containing protein | 0.0028 | 0.0566 | 0.0629 |
Loa Loa (eye worm) | TAR-binding protein | 0.0063 | 0.2102 | 0.2336 |
Toxoplasma gondii | histone lysine methyltransferase SET/SUV39 | 0.0031 | 0.0689 | 0.0146 |
Schistosoma mansoni | family S12 unassigned peptidase (S12 family) | 0.0036 | 0.0913 | 0.0411 |
Loa Loa (eye worm) | RNA binding protein | 0.0063 | 0.2102 | 0.2336 |
Echinococcus granulosus | intermediate filament protein | 0.0028 | 0.0567 | 0.0001 |
Loa Loa (eye worm) | intermediate filament protein | 0.0028 | 0.0567 | 0.0629 |
Mycobacterium ulcerans | aldehyde dehydrogenase | 0.0059 | 0.1954 | 0.1646 |
Entamoeba histolytica | glycosyl hydrolase, family 31 protein | 0.0037 | 0.0972 | 1 |
Brugia malayi | beta-lactamase | 0.0036 | 0.0913 | 0.1014 |
Brugia malayi | TAR-binding protein | 0.0063 | 0.2102 | 0.2336 |
Schistosoma mansoni | methionyl aminopeptidase 1 (M24 family) | 0.022 | 0.9 | 1 |
Leishmania major | hypothetical protein, conserved | 0.0036 | 0.0913 | 0.0411 |
Echinococcus multilocularis | histone lysine methyltransferase setb histone lysine methyltransferase eggless | 0.0031 | 0.0689 | 0.0146 |
Loa Loa (eye worm) | intermediate filament tail domain-containing protein | 0.0028 | 0.0567 | 0.0629 |
Trichomonas vaginalis | set domain proteins, putative | 0.0243 | 1 | 1 |
Mycobacterium tuberculosis | Methionine aminopeptidase MapB (map) (peptidase M) | 0.022 | 0.9 | 0.9598 |
Schistosoma mansoni | histone-lysine n-methyltransferase setb1 | 0.0031 | 0.0689 | 0.0146 |
Schistosoma mansoni | lamin | 0.0028 | 0.0567 | 0.0001 |
Echinococcus multilocularis | lysosomal alpha glucosidase | 0.0167 | 0.6674 | 0.7242 |
Loa Loa (eye worm) | RNA recognition domain-containing protein domain-containing protein | 0.0063 | 0.2102 | 0.2336 |
Plasmodium vivax | hypothetical protein, conserved | 0.0036 | 0.0913 | 0.0411 |
Toxoplasma gondii | aldehyde dehydrogenase | 0.0059 | 0.1954 | 0.1646 |
Mycobacterium ulcerans | fusion of enoyl-CoA hydratase, EchA21 and lipase, LipE | 0.0036 | 0.0913 | 0.0411 |
Echinococcus granulosus | geminin | 0.0168 | 0.6718 | 0.7294 |
Brugia malayi | Intermediate filament tail domain containing protein | 0.0028 | 0.0567 | 0.0629 |
Mycobacterium tuberculosis | Probable hydrolase | 0.0036 | 0.0913 | 0.0395 |
Mycobacterium leprae | PROBABLE METHIONINE AMINOPEPTIDASE MAPA (MAP) (PEPTIDASE M) (MetAP) | 0.022 | 0.9 | 1 |
Brugia malayi | intermediate filament protein | 0.0028 | 0.0567 | 0.0629 |
Brugia malayi | RNA recognition motif domain containing protein | 0.0063 | 0.2102 | 0.2336 |
Brugia malayi | beta-lactamase family protein | 0.0036 | 0.0913 | 0.1014 |
Echinococcus granulosus | lysosomal alpha glucosidase | 0.0167 | 0.6674 | 0.7242 |
Schistosoma mansoni | tar DNA-binding protein | 0.0063 | 0.2102 | 0.1821 |
Leishmania major | methionine aminopeptidase, putative,metallo-peptidase, Clan MG, Family M24 | 0.022 | 0.9 | 1 |
Mycobacterium tuberculosis | Conserved protein | 0.0036 | 0.0913 | 0.0395 |
Loa Loa (eye worm) | hypothetical protein | 0.0028 | 0.0566 | 0.0629 |
Onchocerca volvulus | 0.0036 | 0.0913 | 0.0368 | |
Loa Loa (eye worm) | hypothetical protein | 0.0036 | 0.0913 | 0.1014 |
Plasmodium falciparum | methionine aminopeptidase 1a, putative | 0.022 | 0.9 | 1 |
Brugia malayi | Methionine aminopeptidase protein type I | 0.022 | 0.9 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0036 | 0.0913 | 0.1014 |
Plasmodium vivax | methionine aminopeptidase 1b, putative | 0.022 | 0.9 | 1 |
Plasmodium falciparum | methionine aminopeptidase 1b, putative | 0.022 | 0.9 | 1 |
Loa Loa (eye worm) | DNA-binding protein | 0.0028 | 0.0566 | 0.0629 |
Echinococcus multilocularis | methionyl aminopeptidase 1 (M24 family) | 0.022 | 0.9 | 1 |
Toxoplasma gondii | ABC1 family protein | 0.0036 | 0.0913 | 0.0411 |
Echinococcus multilocularis | tar DNA binding protein | 0.0063 | 0.2102 | 0.1821 |
Echinococcus multilocularis | aldehyde dehydrogenase, mitochondrial | 0.0059 | 0.1954 | 0.1646 |
Trichomonas vaginalis | D-aminoacylase, putative | 0.0036 | 0.0913 | 0.0368 |
Leishmania major | aldehyde dehydrogenase, mitochondrial precursor | 0.0059 | 0.1954 | 0.1646 |
Trypanosoma cruzi | metallo- peptidase, Clan MG, Family M24 | 0.022 | 0.9 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0028 | 0.0566 | 0.0629 |
Trichomonas vaginalis | alpha-glucosidase, putative | 0.0037 | 0.0972 | 0.0431 |
Onchocerca volvulus | 0.0028 | 0.0567 | 0.0001 | |
Loa Loa (eye worm) | methionine aminopeptidase type I | 0.022 | 0.9 | 1 |
Brugia malayi | metallopeptidase family M24 containing protein | 0.0028 | 0.0566 | 0.0629 |
Trichomonas vaginalis | penicillin-binding protein, putative | 0.0036 | 0.0913 | 0.0368 |
Treponema pallidum | methionine aminopeptidase (map) | 0.022 | 0.9 | 1 |
Leishmania major | alpha glucosidase II subunit, putative | 0.0037 | 0.0972 | 0.0482 |
Plasmodium vivax | methionine aminopeptidase 1a, putative | 0.022 | 0.9 | 1 |
Schistosoma mansoni | histone-lysine n-methyltransferase setb1 | 0.0031 | 0.0689 | 0.0146 |
Loa Loa (eye worm) | hypothetical protein | 0.0036 | 0.0913 | 0.1014 |
Trypanosoma cruzi | hypothetical protein, conserved | 0.0037 | 0.0972 | 0.0482 |
Entamoeba histolytica | glycosyl hydrolase, family 31 protein | 0.0037 | 0.0972 | 1 |
Mycobacterium tuberculosis | Probable esterase LipL | 0.0036 | 0.0913 | 0.0395 |
Onchocerca volvulus | 0.0031 | 0.0689 | 0.013 | |
Trichomonas vaginalis | alpha-glucosidase, putative | 0.0037 | 0.0972 | 0.0431 |
Plasmodium vivax | SET domain protein, putative | 0.0031 | 0.0689 | 0.0146 |
Brugia malayi | beta-lactamase family protein | 0.0036 | 0.0913 | 0.1014 |
Trypanosoma cruzi | hypothetical protein, conserved | 0.0037 | 0.0972 | 0.0482 |
Toxoplasma gondii | methionine aminopeptidase | 0.022 | 0.9 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0027 | 0.0544 | 0.0605 |
Echinococcus granulosus | lamin dm0 | 0.0028 | 0.0567 | 0.0001 |
Brugia malayi | metallopeptidase family M24 containing protein | 0.0028 | 0.0566 | 0.0629 |
Trichomonas vaginalis | sucrase-isomaltase, putative | 0.0037 | 0.0972 | 0.0431 |
Trypanosoma brucei | methionine aminopeptidase, type I, putative | 0.022 | 0.9 | 1 |
Toxoplasma gondii | methionine aminopeptidase | 0.022 | 0.9 | 1 |
Mycobacterium ulcerans | hypothetical protein | 0.0036 | 0.0913 | 0.0411 |
Brugia malayi | Glycosyl hydrolases family 31 protein | 0.0037 | 0.0972 | 0.108 |
Loa Loa (eye worm) | beta-lactamase | 0.0036 | 0.0913 | 0.1014 |
Schistosoma mansoni | hypothetical protein | 0.0168 | 0.6718 | 0.7294 |
Loa Loa (eye worm) | hypothetical protein | 0.0036 | 0.0913 | 0.1014 |
Mycobacterium tuberculosis | Probable esterase/lipase LipP | 0.0036 | 0.0913 | 0.0395 |
Mycobacterium tuberculosis | Conserved protein | 0.0036 | 0.0913 | 0.0395 |
Trypanosoma brucei | glucosidase, putative | 0.0037 | 0.0972 | 0.0482 |
Trypanosoma brucei | hypothetical protein, conserved | 0.0036 | 0.0913 | 0.0411 |
Echinococcus multilocularis | musashi | 0.0028 | 0.0567 | 0.0001 |
Mycobacterium tuberculosis | Possible penicillin-binding protein | 0.0228 | 0.9353 | 1 |
Mycobacterium ulcerans | methionine aminopeptidase | 0.022 | 0.9 | 1 |
Trichomonas vaginalis | alpha-glucosidase, putative | 0.0037 | 0.0972 | 0.0431 |
Trypanosoma brucei | metallo- peptidase, Clan MG, Family M24 | 0.022 | 0.9 | 1 |
Echinococcus multilocularis | lysosomal alpha glucosidase | 0.0167 | 0.6674 | 0.7242 |
Loa Loa (eye worm) | metallopeptidase family M24 containing protein | 0.0028 | 0.0566 | 0.0629 |
Brugia malayi | metallopeptidase family M24 containing protein | 0.0028 | 0.0566 | 0.0629 |
Onchocerca volvulus | 0.0036 | 0.0913 | 0.0368 | |
Mycobacterium tuberculosis | Conserved protein | 0.0036 | 0.0913 | 0.0395 |
Mycobacterium leprae | Probable lipase LipE | 0.0036 | 0.0913 | 0.0411 |
Schistosoma mansoni | tar DNA-binding protein | 0.0063 | 0.2102 | 0.1821 |
Loa Loa (eye worm) | glycosyl hydrolase family 31 protein | 0.0037 | 0.0972 | 0.108 |
Chlamydia trachomatis | methionine aminopeptidase | 0.022 | 0.9 | 1 |
Trichomonas vaginalis | maltase-glucoamylase, putative | 0.0037 | 0.0972 | 0.0431 |
Echinococcus granulosus | tar DNA binding protein | 0.0063 | 0.2102 | 0.1821 |
Mycobacterium tuberculosis | Possible conserved lipoprotein LpqK | 0.0036 | 0.0913 | 0.0395 |
Loa Loa (eye worm) | beta-LACTamase domain containing family member | 0.0036 | 0.0913 | 0.1014 |
Trichomonas vaginalis | alpha-glucosidase, putative | 0.0037 | 0.0972 | 0.0431 |
Trypanosoma cruzi | hypothetical protein, conserved | 0.0036 | 0.0913 | 0.0411 |
Mycobacterium tuberculosis | Probable aldehyde dehydrogenase | 0.0059 | 0.1954 | 0.158 |
Trichomonas vaginalis | esterase, putative | 0.0036 | 0.0913 | 0.0368 |
Schistosoma mansoni | tar DNA-binding protein | 0.0063 | 0.2102 | 0.1821 |
Mycobacterium ulcerans | beta-lactamase | 0.0036 | 0.0913 | 0.0411 |
Trichomonas vaginalis | neutral alpha-glucosidase ab precursor, putative | 0.0037 | 0.0972 | 0.0431 |
Schistosoma mansoni | alpha glucosidase | 0.0037 | 0.0972 | 0.0482 |
Brugia malayi | initiation factor 2-associated protein. | 0.0028 | 0.0566 | 0.0629 |
Mycobacterium leprae | conserved hypothetical protein | 0.0036 | 0.0913 | 0.0411 |
Echinococcus multilocularis | beta LACTamase domain containing family member | 0.0036 | 0.0913 | 0.0411 |
Schistosoma mansoni | hypothetical protein | 0.0168 | 0.6718 | 0.7294 |
Echinococcus multilocularis | methionyl aminopeptidase 1 (M24 family) | 0.022 | 0.9 | 1 |
Giardia lamblia | Xaa-Pro dipeptidase | 0.0028 | 0.0566 | 0.5 |
Echinococcus multilocularis | lamin | 0.0028 | 0.0567 | 0.0001 |
Brugia malayi | Hypothetical 52.5 kDa protein ZK945.1 in chromosome II, putative | 0.0036 | 0.0913 | 0.1014 |
Loa Loa (eye worm) | glycosyl hydrolase family 31 protein | 0.0167 | 0.6674 | 0.7415 |
Echinococcus multilocularis | neutral alpha glucosidase AB | 0.0037 | 0.0972 | 0.0482 |
Echinococcus granulosus | lamin | 0.0028 | 0.0567 | 0.0001 |
Wolbachia endosymbiont of Brugia malayi | methionine aminopeptidase | 0.022 | 0.9 | 1 |
Brugia malayi | Pre-SET motif family protein | 0.0031 | 0.0689 | 0.0765 |
Trichomonas vaginalis | D-aminoacylase, putative | 0.0036 | 0.0913 | 0.0368 |
Schistosoma mansoni | histone-lysine n-methyltransferase setb1 | 0.0031 | 0.0689 | 0.0146 |
Trichomonas vaginalis | alpha-glucosidase, putative | 0.0037 | 0.0972 | 0.0431 |
Onchocerca volvulus | 0.0097 | 0.3584 | 0.32 | |
Loa Loa (eye worm) | hypothetical protein | 0.0036 | 0.0913 | 0.1014 |
Brugia malayi | Glycosyl hydrolases family 31 protein | 0.0167 | 0.6674 | 0.7415 |
Echinococcus granulosus | beta LACTamase domain containing family member | 0.0036 | 0.0913 | 0.0411 |
Schistosoma mansoni | tar DNA-binding protein | 0.0063 | 0.2102 | 0.1821 |
Mycobacterium tuberculosis | Probable lipase LipD | 0.0036 | 0.0913 | 0.0395 |
Giardia lamblia | Xaa-Pro dipeptidase | 0.0028 | 0.0566 | 0.5 |
Schistosoma mansoni | histone-lysine n-methyltransferase suv9 | 0.0031 | 0.0689 | 0.0146 |
Schistosoma mansoni | aldehyde dehydrogenase | 0.0059 | 0.1954 | 0.1646 |
Echinococcus multilocularis | histone lysine N methyltransferase SETMAR | 0.0031 | 0.0689 | 0.0146 |
Loa Loa (eye worm) | pre-SET domain-containing protein family protein | 0.0213 | 0.8707 | 0.9674 |
Trypanosoma cruzi | hypothetical protein, conserved | 0.0036 | 0.0913 | 0.0411 |
Mycobacterium ulcerans | lipase LipD | 0.0036 | 0.0913 | 0.0411 |
Echinococcus granulosus | histone lysine methyltransferase setb | 0.0031 | 0.0689 | 0.0146 |
Mycobacterium tuberculosis | Methionine aminopeptidase MapA (map) (peptidase M) (MetAP) | 0.022 | 0.9 | 0.9598 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.
1 literature reference was collected for this gene.