Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Schistosoma mansoni | methionyl aminopeptidase 1 (M24 family) | 0.0046 | 0.3031 | 1 |
Trypanosoma brucei | methionine aminopeptidase, type I, putative | 0.0046 | 0.3031 | 0.5 |
Loa Loa (eye worm) | hypothetical protein | 0.0132 | 1 | 1 |
Onchocerca volvulus | Huntingtin homolog | 0.0132 | 1 | 0.5 |
Loa Loa (eye worm) | methionine aminopeptidase type I | 0.0046 | 0.3031 | 0.3031 |
Plasmodium vivax | methionine aminopeptidase 1a, putative | 0.0046 | 0.3031 | 0.5 |
Echinococcus multilocularis | methionyl aminopeptidase 1 (M24 family) | 0.0046 | 0.3031 | 1 |
Mycobacterium tuberculosis | Methionine aminopeptidase MapB (map) (peptidase M) | 0.0046 | 0.3031 | 0.5 |
Brugia malayi | Methionine aminopeptidase protein type I | 0.0046 | 0.3031 | 0.3031 |
Trypanosoma cruzi | metallo- peptidase, Clan MG, Family M24 | 0.0046 | 0.3031 | 0.5 |
Plasmodium vivax | methionine aminopeptidase 1b, putative | 0.0046 | 0.3031 | 0.5 |
Trypanosoma brucei | methionine aminopeptidase, putative | 0.0046 | 0.3031 | 0.5 |
Chlamydia trachomatis | methionine aminopeptidase | 0.0046 | 0.3031 | 0.5 |
Toxoplasma gondii | methionine aminopeptidase | 0.0046 | 0.3031 | 0.5 |
Schistosoma mansoni | methionyl aminopeptidase 1 (M24 family) | 0.0046 | 0.3031 | 1 |
Plasmodium falciparum | methionine aminopeptidase 1b, putative | 0.0046 | 0.3031 | 0.5 |
Loa Loa (eye worm) | MH2 domain-containing protein | 0.0128 | 0.9727 | 0.9727 |
Mycobacterium leprae | PROBABLE METHIONINE AMINOPEPTIDASE MAPB (MAP) (PEPTIDASE M) | 0.0046 | 0.3031 | 0.5 |
Toxoplasma gondii | methionine aminopeptidase | 0.0046 | 0.3031 | 0.5 |
Mycobacterium ulcerans | methionine aminopeptidase MapB | 0.0046 | 0.3031 | 0.5 |
Echinococcus multilocularis | methionyl aminopeptidase 1 (M24 family) | 0.0046 | 0.3031 | 1 |
Mycobacterium ulcerans | methionine aminopeptidase | 0.0046 | 0.3031 | 0.5 |
Mycobacterium leprae | PROBABLE METHIONINE AMINOPEPTIDASE MAPA (MAP) (PEPTIDASE M) (MetAP) | 0.0046 | 0.3031 | 0.5 |
Loa Loa (eye worm) | hypothetical protein | 0.0132 | 1 | 1 |
Echinococcus granulosus | methionyl aminopeptidase 1 M24 family | 0.0046 | 0.3031 | 1 |
Brugia malayi | MH2 domain containing protein | 0.0128 | 0.9727 | 0.9727 |
Toxoplasma gondii | methionine aminopeptidase, type i, putative | 0.0046 | 0.3031 | 0.5 |
Onchocerca volvulus | Huntingtin homolog | 0.0132 | 1 | 0.5 |
Mycobacterium tuberculosis | Methionine aminopeptidase MapA (map) (peptidase M) (MetAP) | 0.0046 | 0.3031 | 0.5 |
Loa Loa (eye worm) | transcription factor SMAD2 | 0.0128 | 0.9727 | 0.9727 |
Plasmodium falciparum | methionine aminopeptidase 1a, putative | 0.0046 | 0.3031 | 0.5 |
Trypanosoma cruzi | metallo- peptidase, Clan MG, Family M24 | 0.0046 | 0.3031 | 0.5 |
Treponema pallidum | methionine aminopeptidase (map) | 0.0046 | 0.3031 | 0.5 |
Wolbachia endosymbiont of Brugia malayi | methionine aminopeptidase | 0.0046 | 0.3031 | 0.5 |
Trypanosoma brucei | metallo- peptidase, Clan MG, Family M24 | 0.0046 | 0.3031 | 0.5 |
Leishmania major | methionine aminopeptidase, putative,metallo-peptidase, Clan MG, Family M24 | 0.0046 | 0.3031 | 0.5 |
Activity type | Activity value | Assay description | Source | Reference |
---|---|---|---|---|
Kd (binding) | = 0.01 uM | Dissociation constant of the compound with dimeric 16S rRNA RNA construct B | ChEMBL. | 11677142 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.
1 literature reference was collected for this gene.