Detailed information for compound 402201

Basic information

Technical information
  • Name: Unnamed compound
  • MW: 1006.03 | Formula: C47H62F3N7O14
  • H donors: 10 H acceptors: 14 LogP: 3.18 Rotable bonds: 37
    Rule of 5 violations (Lipinski): 4
  • SMILES: CC(C[C@@H](C(=O)N[C@@H](C(=O)C(=O)NCc1ccccc1)CC(F)(F)F)NC(=O)[C@H](C(C)(C)C)NC(=O)[C@H](Cc1ccccc1C)NC(=O)[C@@H](NC(=O)[C@@H](NC(=O)CCC(=O)O)CC(=O)O)CCC(=O)O)C
  • InChi: 1S/C47H62F3N7O14/c1-25(2)20-30(41(67)56-33(23-47(48,49)50)38(65)44(70)51-24-27-13-8-7-9-14-27)55-45(71)39(46(4,5)6)57-43(69)31(21-28-15-11-10-12-26(28)3)54-40(66)29(16-18-35(59)60)53-42(68)32(22-37(63)64)52-34(58)17-19-36(61)62/h7-15,25,29-33,39H,16-24H2,1-6H3,(H,51,70)(H,52,58)(H,53,68)(H,54,66)(H,55,71)(H,56,67)(H,57,69)(H,59,60)(H,61,62)(H,63,64)/t29-,30-,31-,32-,33+,39+/m0/s1
  • InChiKey: FRGWURYHPUCUDI-VNKKIWOVSA-N  


Substructure search Similarity search

Network

Hover on a compound node to display the structore

Synonyms

No synonyms found for this compound

Targets

Known targets for this compound

Species Target name Source Bibliographic reference
Hepatitis C virus Hepatitis C virus serine protease, NS3/NS4A Starlite/ChEMBL References

Predicted pathogen targets for this compound

By orthology
No druggable targets predicted by orthology data
By sequence similarity to non orthologous known druggable targets
Species Potential target Known druggable target Length Alignment span Identity
Mycobacterium tuberculosis Membrane-associated phospholipase C 2 PlcB Hepatitis C virus serine protease, NS3/NS4A   54 aa 49 aa 32.7 %
Schistosoma mansoni hypothetical protein Hepatitis C virus serine protease, NS3/NS4A   54 aa 44 aa 29.5 %
Trypanosoma brucei hypothetical protein, conserved Hepatitis C virus serine protease, NS3/NS4A   54 aa 55 aa 30.9 %
Mycobacterium ulcerans Maf-like protein Hepatitis C virus serine protease, NS3/NS4A   54 aa 44 aa 38.6 %
Schistosoma japonicum expressed protein Hepatitis C virus serine protease, NS3/NS4A   54 aa 44 aa 29.5 %
Trypanosoma brucei expression site-associated gene 3 (ESAG3)-like protein Hepatitis C virus serine protease, NS3/NS4A   54 aa 49 aa 28.6 %
Trypanosoma brucei gambiense expression site-associated gene 3 (ESAG3)-like protein, putative Hepatitis C virus serine protease, NS3/NS4A   54 aa 49 aa 28.6 %
Toxoplasma gondii hypothetical protein Hepatitis C virus serine protease, NS3/NS4A   54 aa 50 aa 28.0 %
Echinococcus granulosus 60S ribosomal protein L8 Hepatitis C virus serine protease, NS3/NS4A   54 aa 48 aa 33.3 %
Entamoeba histolytica hypothetical protein Hepatitis C virus serine protease, NS3/NS4A   54 aa 52 aa 23.1 %
Trypanosoma congolense WD40 repeats, putative Hepatitis C virus serine protease, NS3/NS4A   54 aa 46 aa 28.3 %
Leishmania braziliensis hypothetical protein, conserved Hepatitis C virus serine protease, NS3/NS4A   54 aa 46 aa 26.1 %
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Brugia malayi Immunoglobulin I-set domain containing protein 0.0015 0.0007 0.0003
Trichomonas vaginalis glutaminase, putative 0.0278 0.0921 0.9321
Entamoeba histolytica chromodomain-helicase-DNA-binding protein, putative 0.0024 0.0038 0.017
Trypanosoma cruzi oligopeptidase b 0.0229 0.075 0.2245
Trypanosoma cruzi DNA polymerase kappa, putative 0.0104 0.0315 0.0938
Loa Loa (eye worm) hypothetical protein 0.0017 0.0012 0.0012
Leishmania major target of rapamycin (TOR) kinase 1, putative 0.0038 0.0086 0.0223
Echinococcus multilocularis G-protein coupled receptor, putative 0.0017 0.0012 0.001
Onchocerca volvulus 0.0017 0.0012 0.0006
Schistosoma mansoni phosphoglycerate kinase 0.0181 0.0582 0.0579
Onchocerca volvulus DNA topoisomerase 2 homolog 0.0045 0.0111 0.0105
Echinococcus multilocularis tyrosyl DNA phosphodiesterase 1 0.007 0.0197 0.0196
Echinococcus multilocularis dynamin 1 protein 0.0133 0.0418 0.0416
Trypanosoma cruzi DNA polymerase beta thumb, putative 0.0045 0.0111 0.0324
Toxoplasma gondii phosphofructokinase domain-containing protein 0.0031 0.0062 0.0152
Loa Loa (eye worm) hypothetical protein 0.0054 0.014 0.014
Echinococcus granulosus dro:myosuppressin receptor 0.0017 0.0012 0.001
Brugia malayi hypothetical protein 0.0017 0.0012 0.0008
Brugia malayi RNA, U transporter 1 0.0076 0.0217 0.0214
Echinococcus multilocularis transient receptor potential gamma protein 0.0092 0.0274 0.0273
Trichomonas vaginalis conserved hypothetical protein 0.0029 0.0056 0.0538
Echinococcus granulosus FTZ F1 alpha 0.0027 0.0048 0.0046
Echinococcus multilocularis Transcription factor, JmjC domain containing protein 0.0062 0.0171 0.0169
Brugia malayi TAR-binding protein 0.0115 0.0352 0.0349
Trypanosoma brucei DNA polymerase kappa, putative 0.0104 0.0315 0.0914
Echinococcus granulosus dna polymerase eta 0.0103 0.0311 0.0309
Entamoeba histolytica protein kinase rad3, putative 0.0021 0.0028 0.0069
Trypanosoma cruzi Heat shock protein 83, putative 0.0222 0.0726 0.2173
Trichomonas vaginalis PIKK family atypical protein kinase 0.0038 0.0086 0.0841
Trypanosoma brucei heat shock protein, putative 0.0222 0.0726 0.2152
Trichomonas vaginalis two component sensor and regulator histidine kinase bacteria, putative 0.0045 0.0111 0.1099
Brugia malayi ATP-dependent DNA helicase, RecQ family protein 0.0021 0.0027 0.0023
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0027 0.0048 0.0044
Loa Loa (eye worm) GTP-binding nuclear protein RAN/TC4 0.002 0.0022 0.0022
Trichomonas vaginalis Clan SC, family S28, unassigned serine peptidase 0.0021 0.0027 0.0242
Echinococcus granulosus phosphoglycerate kinase 1 0.0181 0.0582 0.058
Loa Loa (eye worm) hypothetical protein 0.0023 0.0035 0.0035
Trichomonas vaginalis ap endonuclease, putative 0.0033 0.0069 0.0669
Trypanosoma brucei DNA polymerase IV, putative 0.0104 0.0315 0.0914
Echinococcus granulosus Nuclear hormone receptor family member nhr 41 0.0027 0.0048 0.0046
Entamoeba histolytica acyl-coA synthetase, putative 0.0023 0.0035 0.0135
Plasmodium vivax multidomain scavenger receptor, putative 0.0042 0.0099 0.1187
Loa Loa (eye worm) hypothetical protein 0.0027 0.0048 0.0048
Echinococcus granulosus rhodopsin orphan GPCR 0.0017 0.0012 0.001
Mycobacterium tuberculosis Probable protease II PtrBb [second part] (oligopeptidase B) 0.0229 0.075 1
Echinococcus granulosus neuropeptide Y receptor 0.0017 0.0012 0.001
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0024 0.0038 0.0357
Echinococcus granulosus heat shock protein 75 kDa mitochondrial 0.0091 0.027 0.0269
Mycobacterium tuberculosis Fatty-acid-AMP ligase FadD30 (fatty-acid-AMP synthetase) (fatty-acid-AMP synthase) 0.0017 0.0014 0.0045
Mycobacterium leprae PROBABLE ENDONUCLEASE IV END (ENDODEOXYRIBONUCLEASE IV) (APURINASE) 0.0081 0.0237 0.2953
Loa Loa (eye worm) hypothetical protein 0.0017 0.0012 0.0012
Treponema pallidum 4'-phosphopantetheinyl transferase 0.0019 0.0022 0.0075
Trichomonas vaginalis glucosylceramidase, putative 0.017 0.0544 0.5494
Schistosoma mansoni ubiquitously transcribed sex (X/Y) chromosome tetratricopeptide repeat protein-related 0.0017 0.0012 0.0008
Mycobacterium ulcerans 4'-phosphopantetheinyl transferase 0.0019 0.0022 0.0081
Loa Loa (eye worm) hypothetical protein 0.0017 0.0012 0.0012
Echinococcus multilocularis DNA topoisomerase 2 alpha 0.0045 0.0111 0.0109
Toxoplasma gondii 6-phosphofructokinase 0.0031 0.0062 0.0152
Leishmania major DNA topoisomerase ii 0.0045 0.0111 0.03
Brugia malayi putative neuropeptide receptor 0.0017 0.0012 0.0008
Entamoeba histolytica Phosphatidylinositol 3- and 4-kinase family 0.0021 0.0028 0.0069
Brugia malayi hypothetical protein 0.0029 0.0054 0.005
Loa Loa (eye worm) hypothetical protein 0.0021 0.0028 0.0028
Echinococcus multilocularis G protein coupled 5 hydroxytryptamine receptor 0.0017 0.0012 0.001
Leishmania major heat shock protein 83-1 0.0222 0.0726 0.2152
Brugia malayi Intermediate filament tail domain containing protein 0.0029 0.0053 0.005
Mycobacterium tuberculosis Probable sensor protein KdpD 0.0045 0.0111 0.1356
Schistosoma mansoni biogenic amine (octopamine/dopamine) receptor 0.0017 0.0012 0.0008
Schistosoma mansoni amine GPCR 0.0017 0.0012 0.0008
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0017 0.0014 0.0034
Echinococcus granulosus ATP dependent DNA helicase Q1 0.0021 0.0027 0.0025
Echinococcus multilocularis g protein linked acetylcholine receptor gar 2a 0.0017 0.0012 0.001
Leishmania major heat shock protein 83-1 0.0222 0.0726 0.2152
Loa Loa (eye worm) hypothetical protein 0.0229 0.075 0.075
Leishmania major heat shock protein 83-1 0.0222 0.0726 0.2152
Trichomonas vaginalis conserved hypothetical protein 0.0024 0.0038 0.0357
Loa Loa (eye worm) pyruvate kinase 0.0035 0.0077 0.0077
Brugia malayi hypothetical protein 0.0045 0.0109 0.0105
Brugia malayi exodeoxyribonuclease III family protein 0.0033 0.0069 0.0065
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0017 0.0014 0.0034
Giardia lamblia Pms1-like protein 0.0045 0.0111 0.0994
Loa Loa (eye worm) hypothetical protein 0.0017 0.0012 0.0012
Echinococcus multilocularis ecdysone induced protein 78C 0.0027 0.0048 0.0046
Schistosoma mansoni nuclear hormone receptor 0.0027 0.0048 0.0044
Loa Loa (eye worm) animal heme peroxidase 0.1364 0.4696 0.4696
Trypanosoma cruzi mitochondrial DNA polymerase beta, putative 0.0321 0.1068 0.3201
Echinococcus granulosus GPCR family 2 0.0143 0.0451 0.0449
Trypanosoma brucei dynamin-1-like protein 0.0133 0.0418 0.1223
Brugia malayi Nuclear hormone receptor family member nhr-41 0.0027 0.0048 0.0044
Brugia malayi Phosphatidylinositol 3- and 4-kinase family protein 0.0021 0.0028 0.0025
Echinococcus granulosus melanoma receptor tyrosine protein kinase 0.0166 0.0531 0.053
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0017 0.0012 0.001
Plasmodium falciparum peptidase, putative 0.0229 0.075 1
Mycobacterium ulcerans acyl-CoA synthetase 0.0023 0.0035 0.0225
Brugia malayi O-Glycosyl hydrolase family 30 protein 0.0259 0.0854 0.085
Schistosoma mansoni neuropeptide f receptor 76f 0.0017 0.0012 0.0008
Giardia lamblia Fructose-bisphosphate aldolase 0.0298 0.0988 1
Mycobacterium tuberculosis Possible two component sensor kinase TcrY 0.0045 0.0111 0.1356
Plasmodium falciparum thioredoxin reductase 0.0017 0.0014 0.0035
Schistosoma mansoni dynamin 0.0144 0.0453 0.045
Schistosoma mansoni chromobox protein-related (chromobox 1) (heterochromatin 1) 0.0024 0.0038 0.0034
Schistosoma mansoni Tr4/Tr2 (homologue) 0.0027 0.0048 0.0044
Schistosoma mansoni hypothetical protein 0.0173 0.0554 0.055
Entamoeba histolytica acyl-CoA synthetase, putative 0.0023 0.0035 0.0135
Toxoplasma gondii hypothetical protein 0.0229 0.075 0.2224
Loa Loa (eye worm) hypothetical protein 0.0028 0.0051 0.0051
Plasmodium falciparum LCCL domain-containing protein 0.0042 0.0099 0.1187
Leishmania major pyruvate kinase 0.0035 0.0077 0.0196
Echinococcus multilocularis phosphatidylinositol 3 and 4 kinase 0.0038 0.0086 0.0084
Schistosoma mansoni pyruvate kinase 0.0035 0.0077 0.0073
Brugia malayi Serotonin/octopamine receptor family protein 7 0.0017 0.0012 0.0008
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0017 0.0012 0.0008
Trypanosoma brucei DNA damage repair protein, putative 0.0023 0.0035 0.0072
Loa Loa (eye worm) hypothetical protein 0.1364 0.4696 0.4696
Onchocerca volvulus 0.0056 0.0148 0.0142
Brugia malayi G protein-coupled receptor F59B2.13 0.0017 0.0012 0.0008
Echinococcus granulosus retinoic acid receptor rxr beta a 0.0027 0.0048 0.0046
Echinococcus granulosus pyruvate kinase 0.0018 0.0017 0.0015
Brugia malayi CHD4 protein 0.0024 0.0038 0.0034
Trichomonas vaginalis PIKK family atypical protein kinase 0.0038 0.0086 0.0841
Loa Loa (eye worm) hypothetical protein 0.0152 0.0482 0.0482
Brugia malayi Inositol-1 0.0039 0.009 0.0087
Brugia malayi prolyl oligopeptidase family protein 0.0229 0.075 0.0747
Toxoplasma gondii heat shock protein 90, putative 0.0222 0.0726 0.2152
Toxoplasma gondii phosphoglycerate kinase PGKI 0.0181 0.0582 0.1718
Loa Loa (eye worm) hypothetical protein 0.1364 0.4696 0.4696
Echinococcus multilocularis phd:f box containing protein 0.0017 0.0012 0.001
Mycobacterium leprae PROBABLE PROTEASE II PTRBB (OLIGOPEPTIDASE B) 0.0229 0.075 1
Loa Loa (eye worm) G-protein-linked acetylcholine receptor protein 2 0.0017 0.0012 0.0012
Entamoeba histolytica serine carboxypeptidase (S28) family protein 0.0021 0.0027 0.0053
Onchocerca volvulus Bile acid receptor homolog 0.0027 0.0048 0.0042
Schistosoma mansoni rotamase 0.0035 0.0077 0.0074
Schistosoma mansoni tar DNA-binding protein 0.0115 0.0352 0.0349
Plasmodium falciparum heterochromatin protein 1 0.0024 0.0038 0.0356
Toxoplasma gondii Hsp90 domain-containing protein 0.0091 0.027 0.0779
Mycobacterium tuberculosis Two component sensor histidine kinase TrcS 0.0045 0.0111 0.1356
Trichomonas vaginalis phosphofructokinase, putative 0.0115 0.0355 0.3573
Trichomonas vaginalis conserved hypothetical protein 0.0024 0.0038 0.0357
Trypanosoma cruzi phosphatidylinositol 3-related kinase, putative 0.0038 0.0086 0.0249
Leishmania major heat shock protein 83-1 0.0222 0.0726 0.2152
Plasmodium vivax hypothetical protein, conserved 0.0229 0.075 1
Echinococcus granulosus G protein coupled receptor 139 0.0017 0.0012 0.001
Brugia malayi Hsp90 protein 0.0091 0.027 0.0267
Trypanosoma brucei DNA polymerase beta thumb, putative 0.0045 0.0111 0.0298
Mycobacterium tuberculosis Probable two component sensor kinase 0.0045 0.0111 0.1356
Mycobacterium tuberculosis Probable oxidoreductase 0.0127 0.0396 0.5214
Echinococcus multilocularis g protein coupled receptor 0.0017 0.0012 0.001
Echinococcus granulosus pyruvate kinase 0.0018 0.0017 0.0015
Brugia malayi jmjC domain containing protein 0.0017 0.0012 0.0008
Trypanosoma brucei DNA polymerase kappa, putative 0.0104 0.0315 0.0914
Loa Loa (eye worm) hypothetical protein 0.0017 0.0012 0.0012
Loa Loa (eye worm) hypothetical protein 0.0017 0.0012 0.0012
Mycobacterium ulcerans two component system response phosphate sensor kinase, PhoR 0.0045 0.0111 0.1068
Onchocerca volvulus 0.1364 0.4696 0.4693
Plasmodium vivax SET domain protein, putative 0.0032 0.0064 0.0708
Trypanosoma brucei Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase, putative 0.0045 0.0111 0.03
Echinococcus granulosus Ankyrin 0.0015 0.0007 0.0005
Onchocerca volvulus 0.0029 0.0053 0.0047
Trichomonas vaginalis PIKK family atypical protein kinase 0.0038 0.0086 0.0841
Mycobacterium tuberculosis Probable chain -fatty-acid-CoA ligase FadD13 (fatty-acyl-CoA synthetase) 0.0023 0.0035 0.0321
Loa Loa (eye worm) heterochromatin protein 1 0.0086 0.0253 0.0253
Loa Loa (eye worm) intermediate filament protein 0.0029 0.0053 0.0053
Plasmodium vivax hypothetical protein, conserved 0.0024 0.0038 0.0356
Brugia malayi hypothetical protein 0.0017 0.0012 0.0008
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0032 0.0064 0.006
Loa Loa (eye worm) hypothetical protein 0.0024 0.0037 0.0037
Echinococcus multilocularis serine protein kinase ATM 0.0021 0.0028 0.0026
Toxoplasma gondii ATPase/histidine kinase/DNA gyrase B/HSP90 domain-containing protein 0.0045 0.0111 0.03
Loa Loa (eye worm) hypothetical protein 0.0027 0.0047 0.0047
Trichomonas vaginalis lysosomal pro-X carboxypeptidase, putative 0.0021 0.0027 0.0242
Echinococcus multilocularis dipeptidyl aminopeptidaseprotein 0.289 1 1
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0017 0.0014 0.0034
Leishmania major DNA polymerase kappa, putative 0.0083 0.0241 0.0692
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0128 0.0399 0.0395
Mycobacterium leprae PUTATIVE TWO COMPONENT SENSOR HISTIDINE KINASE SENX3 0.0045 0.0111 0.1229
Mycobacterium tuberculosis Putative ferredoxin reductase 0.0115 0.0352 0.4613
Echinococcus multilocularis GTP binding nuclear protein Ran 0.002 0.0022 0.002
Loa Loa (eye worm) hypothetical protein 0.0024 0.0038 0.0038
Loa Loa (eye worm) hypothetical protein 0.0092 0.0274 0.0274
Toxoplasma gondii pyruvate kinase PyKII 0.0018 0.0017 0.0016
Onchocerca volvulus 0.0017 0.0012 0.0006
Trichomonas vaginalis Clan SC, family S28, unassigned serine peptidase 0.0021 0.0027 0.0242
Trichomonas vaginalis PIKK family atypical protein kinase 0.0038 0.0086 0.0841
Mycobacterium tuberculosis Conserved hypothetical protein 0.0021 0.0028 0.0234
Trichomonas vaginalis chromobox protein, putative 0.0086 0.0253 0.2539
Loa Loa (eye worm) hypothetical protein 0.0229 0.075 0.075
Echinococcus granulosus heat shock protein 90 0.0177 0.0569 0.0567
Echinococcus granulosus rhodopsin orphan GPCR 0.0017 0.0012 0.001
Plasmodium falciparum AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.0033 0.0069 0.0773
Echinococcus multilocularis rhodopsin orphan GPCR 0.0017 0.0012 0.001
Schistosoma mansoni neuropeptide receptor 0.0017 0.0012 0.0008
Echinococcus granulosus Transcription factor JmjC domain containing protein 0.0062 0.0171 0.0169
Trypanosoma brucei dihydrolipoamide dehydrogenase 0.0017 0.0014 0.0008
Schistosoma mansoni lamin 0.0029 0.0053 0.005
Plasmodium falciparum dynamin-like protein 0.0133 0.0418 0.5498
Trichomonas vaginalis PIKK family atypical protein kinase 0.0038 0.0086 0.0841
Echinococcus granulosus growth hormone secretagogue receptor type 1 0.0017 0.0012 0.001
Brugia malayi GTP-binding regulatory protein Gs alpha-S chain, putative 0.0128 0.0399 0.0395
Trypanosoma brucei phosphoglycerate kinase 0.0181 0.0582 0.1718
Trypanosoma cruzi myo-inositol-1(or 4)-monophosphatase 1, putative 0.0039 0.009 0.0262
Mycobacterium ulcerans two component sensory transduction histidine kinase MtrB 0.0045 0.0111 0.1068
Leishmania major heat shock protein 83-1 0.0222 0.0726 0.2152
Loa Loa (eye worm) DnaJ domain-containing protein 0.0061 0.0167 0.0167
Giardia lamblia Flap structure-specific endonuclease 0.0028 0.005 0.0366
Giardia lamblia Sgs1 DNA helicase, putative 0.0021 0.0027 0.013
Plasmodium vivax holo-[acyl-carrier-protein] synthase, putative 0.0019 0.0022 0.0134
Loa Loa (eye worm) Pin1-type peptidyl-prolyl cis-trans isomerase 0.0035 0.0077 0.0077
Entamoeba histolytica serine carboxypeptidase (S28) family protein 0.0021 0.0027 0.0053
Trypanosoma cruzi pyruvate kinase 2, putative 0.0035 0.0077 0.0223
Onchocerca volvulus 0.012 0.037 0.0364
Loa Loa (eye worm) jmjC domain-containing protein 0.0017 0.0012 0.0012
Schistosoma mansoni neuropeptide F-like receptor 0.0017 0.0012 0.0008
Loa Loa (eye worm) hypothetical protein 0.0081 0.0237 0.0237
Echinococcus granulosus neuropeptide receptor 0.0017 0.0012 0.001
Brugia malayi SET domain containing protein 0.0025 0.0042 0.0039
Entamoeba histolytica tyrosyl-DNA phosphodiesterase, putative 0.007 0.0197 0.1819
Leishmania major dipeptidyl-peptidase 8-like serine peptidase, putative,serine peptidase, Clan SC, Family S9B 0.0972 0.3331 1
Entamoeba histolytica 90 kDa heat shock protein, putative 0.0091 0.027 0.2573
Entamoeba histolytica hypothetical protein 0.0038 0.0087 0.0672
Trypanosoma brucei apurinic/apyrimidinic endonuclease, putative 0.0033 0.0069 0.0172
Loa Loa (eye worm) hypothetical protein 0.0024 0.0038 0.0038
Chlamydia trachomatis pyruvate kinase 0.0035 0.0077 0.1104
Onchocerca volvulus 0.0021 0.0027 0.0021
Trypanosoma brucei RNA helicase, putative 0.0215 0.0701 0.2076
Echinococcus granulosus dnaJ subfamily C 6 0.0061 0.0167 0.0165
Trichomonas vaginalis PIKK family atypical protein kinase 0.0021 0.0028 0.0258
Loa Loa (eye worm) CHromoDomain protein family member 0.0024 0.0038 0.0038
Schistosoma mansoni tar DNA-binding protein 0.0115 0.0352 0.0349
Leishmania major hypothetical protein, conserved 0.0198 0.0642 0.1897
Schistosoma mansoni ataxia telangiectasia mutated (atm) 0.0021 0.0028 0.0025
Brugia malayi Isocitrate dehydrogenase 0.0043 0.0104 0.0101
Trypanosoma cruzi isocitrate dehydrogenase, putative 0.0043 0.0104 0.0305
Plasmodium falciparum ATP-dependent DNA helicase Q1 0.0021 0.0027 0.0207
Loa Loa (eye worm) cytoplasmic intermediate filament protein 0.0015 0.0007 0.0007
Plasmodium falciparum importin beta, putative 0.0027 0.0047 0.0472
Chlamydia trachomatis DNA gyrase subunit B 0.0045 0.0111 0.1707
Trichomonas vaginalis DNA helicase recq1, putative 0.0021 0.0027 0.0245
Trypanosoma cruzi heat shock protein 85, putative 0.0177 0.0569 0.1701
Brugia malayi ATP-dependent DNA helicase, RecQ family protein 0.0021 0.0027 0.0023
Leishmania major DNA damage repair protein, putative 0.0023 0.0035 0.0072
Mycobacterium ulcerans acyl-CoA synthetase 0.0023 0.0035 0.0225
Trypanosoma brucei importin beta-1 subunit, putative 0.0027 0.0047 0.0105
Leishmania major target of rapamycin kinase (TOR) kinase 3 0.0038 0.0086 0.0223
Schistosoma mansoni 3-hydroxyacyl-CoA dehydrogenase 0.0065 0.018 0.0176
Echinococcus multilocularis g protein coupled receptor 0.0017 0.0012 0.001
Echinococcus multilocularis NADP dependent isocitrate dehydrogenase 0.0043 0.0104 0.0102
Onchocerca volvulus 0.0017 0.0012 0.0006
Echinococcus granulosus biogenic amine 5HT receptor 0.0017 0.0012 0.001
Mycobacterium ulcerans long-chain-fatty-acid--CoA ligase 0.0023 0.0035 0.0225
Plasmodium falciparum ATP-dependent 6-phosphofructokinase 0.0031 0.0062 0.0684
Trypanosoma cruzi hypothetical protein, conserved 0.0229 0.075 0.2245
Mycobacterium ulcerans 6-phosphofructokinase 0.0115 0.0355 0.3756
Echinococcus multilocularis Nuclear hormone receptor family member nhr 41 0.0027 0.0048 0.0046
Toxoplasma gondii flap structure-specific endonuclease 1, putative 0.0028 0.005 0.0115
Schistosoma mansoni peptide (allatostatin/somatostatin)-like receptor 0.0017 0.0012 0.0008
Trichomonas vaginalis pyruvate kinase, putative 0.0035 0.0077 0.0752
Schistosoma mansoni lamin 0.0029 0.0053 0.005
Loa Loa (eye worm) hypothetical protein 0.0017 0.0012 0.0012
Trypanosoma cruzi phosphatidylinositol kinase related protein, putative 0.0021 0.0028 0.0076
Echinococcus granulosus transcription factor eb 0.0186 0.0602 0.06
Echinococcus granulosus FKBP12 rapamycin complex associated protein 0.0038 0.0086 0.0084
Trichomonas vaginalis glucosylceramidase, putative 0.017 0.0544 0.5494
Trypanosoma brucei trypanothione reductase 0.005 0.0128 0.0351
Trypanosoma brucei dihydrolipoyl dehydrogenase 0.0017 0.0014 0.0008
Loa Loa (eye worm) hypothetical protein 0.0017 0.0012 0.0012
Trichomonas vaginalis PIKK family atypical protein kinase 0.0038 0.0086 0.0841
Leishmania major PAS-domain containing phosphoglycerate kinase, putative 0.0066 0.0184 0.052
Trypanosoma cruzi DNA topoisomerase II, putative 0.0045 0.0111 0.0325
Loa Loa (eye worm) hypothetical protein 0.0017 0.0014 0.0014
Mycobacterium ulcerans endonuclease IV 0.0081 0.0237 0.2452
Giardia lamblia Grp94/Hsp90 0.0177 0.0569 0.5695
Echinococcus granulosus lamin 0.0029 0.0053 0.0052
Echinococcus multilocularis dnaJ subfamily C 6 0.0061 0.0167 0.0165
Trypanosoma brucei hypothetical protein, conserved 0.0023 0.0035 0.0072
Echinococcus multilocularis neuropeptide Y receptor 0.0017 0.0012 0.001
Trypanosoma cruzi dipeptidyl-peptidase 8-like serine peptidase 0.0972 0.3331 1
Onchocerca volvulus Steroid hormone receptor family member cnr14 homolog 0.0027 0.0048 0.0042
Giardia lamblia Dynamin 0.0133 0.0418 0.4142
Brugia malayi glutathione reductase 0.005 0.0128 0.0125
Trypanosoma cruzi JmjC domain, hydroxylase, putative 0.0017 0.0012 0.0027
Onchocerca volvulus Dipeptidyl peptidase family member 1 homolog 0.289 1 1
Loa Loa (eye worm) hypothetical protein 0.1364 0.4696 0.4696
Trichomonas vaginalis conserved hypothetical protein 0.0054 0.014 0.1392
Echinococcus multilocularis epidermal growth factor receptor 0.0166 0.0531 0.053
Brugia malayi nuclear hormone receptor 0.0027 0.0048 0.0044
Trypanosoma cruzi tyrosyl-DNA Phosphodiesterase (Tdp1), putative 0.007 0.0197 0.0585
Mycobacterium tuberculosis Dihydrolipoamide dehydrogenase LpdC (lipoamide reductase (NADH)) (lipoyl dehydrogenase) (dihydrolipoyl dehydrogenase) (diaphoras 0.0127 0.0396 0.5214
Brugia malayi hypothetical protein 0.0038 0.0087 0.0083
Toxoplasma gondii GTP-binding nuclear protein ran/tc4 0.002 0.0022 0.0031
Echinococcus granulosus heat shock protein 90 0.0222 0.0726 0.0725
Trichomonas vaginalis glucosylceramidase, putative 0.0179 0.0576 0.5816
Plasmodium vivax hypothetical protein, conserved 0.0045 0.0111 0.1347
Giardia lamblia Serine peptidase, putative 0.0021 0.0027 0.0127
Mycobacterium ulcerans fatty-acid-CoA ligase 0.0023 0.0035 0.0225
Echinococcus granulosus transient receptor potential gamma protein 0.0092 0.0274 0.0273
Schistosoma mansoni jumonji/arid domain-containing protein 0.0062 0.0171 0.0167
Echinococcus multilocularis nuclear receptor subfamily 1 group D 0.0014 0.0003 0.0002
Echinococcus multilocularis bloom syndrome protein 0.0021 0.0027 0.0025
Echinococcus granulosus FTZ F1 nuclear receptor protein 0.0027 0.0048 0.0046
Echinococcus granulosus Polycystic kidney disease protein 0.0042 0.0099 0.0098
Trichomonas vaginalis Clan SC, family S28, unassigned serine peptidase 0.0021 0.0027 0.0242
Brugia malayi FAT domain containing protein 0.0017 0.0011 0.0008
Trichomonas vaginalis heat shock protein, putative 0.0136 0.0428 0.4311
Giardia lamblia GTP-binding nuclear protein RAN/TC4 0.002 0.0022 0.008
Loa Loa (eye worm) hypothetical protein 0.0024 0.0038 0.0038
Trypanosoma cruzi flap endonuclease-1 (FEN-1), putative 0.0028 0.005 0.0141
Schistosoma mansoni peptide (FMRFamide/somatostatin)-like receptor 0.0017 0.0012 0.0008
Toxoplasma gondii inositol(myo)-1(or 4)-monophosphatase 2, putative 0.0039 0.009 0.0236
Trypanosoma cruzi JmjC domain, hydroxylase, putative 0.0017 0.0012 0.0027
Echinococcus multilocularis isocitrate dehydrogenase 2 (NADP+) 0.0043 0.0104 0.0102
Trichomonas vaginalis PIKK family atypical protein kinase 0.0021 0.0028 0.0258
Leishmania major myo-inositol-1(or 4)-monophosphatase 1, putative 0.0039 0.009 0.0236
Entamoeba histolytica hypothetical protein 0.0038 0.0087 0.0672
Echinococcus granulosus neuropeptides capa receptor 0.0017 0.0012 0.001
Echinococcus granulosus neuropeptides capa receptor 0.0017 0.0012 0.001
Trypanosoma cruzi heat shock protein 85, putative 0.0222 0.0726 0.2173
Loa Loa (eye worm) hypothetical protein 0.1364 0.4696 0.4696
Loa Loa (eye worm) RNA recognition domain-containing protein domain-containing protein 0.0115 0.0352 0.0352
Schistosoma mansoni phosphatidylserine receptor 0.0017 0.0012 0.0008
Plasmodium vivax dynamin protein, putative 0.0133 0.0418 0.5498
Echinococcus multilocularis terminal deoxycytidyl transferase rev1 0.0076 0.0217 0.0215
Echinococcus granulosus acylamino acid releasing enzyme 0.0229 0.075 0.0748
Loa Loa (eye worm) thioredoxin reductase 0.005 0.0128 0.0128
Echinococcus multilocularis Basic leucine zipper (bZIP) transcription 0.0038 0.0087 0.0085
Mycobacterium tuberculosis Probable endonuclease IV End (endodeoxyribonuclease IV) (apurinase) 0.0081 0.0237 0.3054
Trypanosoma brucei heat shock protein, putative 0.0222 0.0726 0.2152
Trypanosoma cruzi DNA polymerase beta thumb, putative 0.0045 0.0111 0.0324
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0024 0.0038 0.0357
Echinococcus multilocularis serotonin receptor 0.0017 0.0012 0.001
Chlamydia trachomatis fructose-6-phosphate phosphotransferase 0.0031 0.0062 0.0845
Plasmodium falciparum flap endonuclease 1 0.0028 0.005 0.0518
Schistosoma mansoni importin beta-1 0.0027 0.0047 0.0043
Loa Loa (eye worm) TYRA-2 protein 0.0017 0.0012 0.0012
Echinococcus multilocularis transient receptor potential ion channel A 0.0089 0.0264 0.0262
Toxoplasma gondii exonuclease III APE 0.0033 0.0069 0.0172
Echinococcus granulosus Jumonji AT rich interactive domain 1B 0.0017 0.0012 0.001
Echinococcus granulosus pyruvate kinase 0.0035 0.0077 0.0075
Loa Loa (eye worm) pyruvate kinase 0.0035 0.0077 0.0077
Brugia malayi prolyl oligopeptidase family protein 0.0229 0.075 0.0747
Echinococcus multilocularis Lysosomal Pro X carboxypeptidase 0.0021 0.0027 0.0025
Schistosoma mansoni hypothetical protein 0.0285 0.0944 0.0941
Brugia malayi Nuclear hormone receptor family member nhr-40 0.0027 0.0048 0.0044
Echinococcus multilocularis orexin receptor type 2 0.0017 0.0012 0.001
Mycobacterium tuberculosis Probable exodeoxyribonuclease III protein XthA (exonuclease III) (EXO III) (AP endonuclease VI) 0.0033 0.0069 0.0783
Loa Loa (eye worm) hypothetical protein 0.0015 0.0007 0.0007
Trypanosoma cruzi serine carboxypeptidase S28, putative 0.0021 0.0027 0.0072
Trichomonas vaginalis phosphofructokinase, putative 0.0115 0.0355 0.3573
Schistosoma mansoni intermediate filament proteins 0.0029 0.0053 0.005
Trichomonas vaginalis PIKK family atypical protein kinase 0.0038 0.0086 0.0841
Echinococcus multilocularis netrin receptor unc 5 0.0015 0.0007 0.0005
Plasmodium vivax flap endonuclease 1, putative 0.0028 0.005 0.0518
Trichomonas vaginalis PIKK family atypical protein kinase 0.0038 0.0086 0.0841
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0017 0.0014 0.0034
Echinococcus granulosus allatostatin A receptor 0.0017 0.0012 0.001
Echinococcus granulosus thioredoxin glutathione reductase 0.005 0.0128 0.0126
Trichomonas vaginalis PIKK family atypical protein kinase 0.0021 0.0028 0.0258
Chlamydia trachomatis endonuclease IV 0.0081 0.0237 0.3919
Echinococcus granulosus neuropeptide receptor A26 0.164 0.5654 0.5653
Entamoeba histolytica dipeptidyl-peptidase, putative 0.0229 0.075 0.7536
Trichomonas vaginalis glutathione reductase, putative 0.0017 0.0014 0.0116
Plasmodium vivax heterochromatin protein 1, putative 0.0024 0.0038 0.0356
Loa Loa (eye worm) hypothetical protein 0.0021 0.0027 0.0027
Echinococcus multilocularis muscleblind protein 0.0152 0.0482 0.0481
Schistosoma mansoni neuropeptide receptor 0.0017 0.0012 0.0008
Brugia malayi ImpB/MucB/SamB family protein 0.0103 0.0311 0.0308
Schistosoma mansoni nuclear hormone receptor nor-1/nor-2 0.0027 0.0048 0.0044
Leishmania major heat shock protein 83-1 0.0222 0.0726 0.2152
Leishmania major mitochondrial DNA polymerase beta-PAK, putative 0.0152 0.0481 0.1415
Schistosoma mansoni tar DNA-binding protein 0.0115 0.0352 0.0349
Echinococcus granulosus serine protein kinase ATM 0.0021 0.0028 0.0026
Leishmania major apurinic/apyrimidinic endonuclease-redox protein 0.0033 0.0069 0.0172
Echinococcus multilocularis tumor protein p63 0.0331 0.1106 0.1104
Echinococcus multilocularis peroxidasin 0.1364 0.4696 0.4695
Echinococcus multilocularis heat shock protein 90 0.0222 0.0726 0.0725
Trypanosoma cruzi myo-inositol-1(or 4)-monophosphatase 1, putative 0.0039 0.009 0.0262
Echinococcus multilocularis FKBP12 rapamycin complex associated protein 0.0038 0.0086 0.0084
Trypanosoma brucei DNA damage repair protein, putative 0.0023 0.0035 0.0072
Trichomonas vaginalis PIKK family atypical protein kinase 0.0038 0.0086 0.0841
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0024 0.0038 0.0357
Brugia malayi dihydrolipoyl dehydrogenase, mitochondrial precursor, putative 0.0017 0.0014 0.0011
Trichomonas vaginalis phosphofructokinase, putative 0.0031 0.0062 0.0602
Echinococcus granulosus heat shock protein heat shock protein 90 alpha 0.0177 0.0569 0.0567
Schistosoma mansoni ataxia telangiectasia mutated (atm)-related 0.0038 0.0086 0.0082
Trichomonas vaginalis conserved hypothetical protein 0.0021 0.0027 0.0242
Onchocerca volvulus Dual oxidase homolog 0.1364 0.4696 0.4693
Toxoplasma gondii BRCA1 C Terminus (BRCT) domain-containing protein 0.003 0.006 0.0145
Leishmania major target of rapamycin (TOR) kinase 2, putative 0.0038 0.0086 0.0223
Echinococcus granulosus insulin growth factor 1 receptor beta 0.0099 0.0299 0.0297
Plasmodium vivax importin-beta 2, putative 0.0027 0.0047 0.0472
Trypanosoma brucei phosphoglycerate kinase 0.0066 0.0184 0.052
Echinococcus multilocularis short transient receptor potential channel 6 0.0061 0.0166 0.0164
Loa Loa (eye worm) RecQ helicase 0.0021 0.0027 0.0027
Schistosoma mansoni glutaminase 0.0278 0.0921 0.0918
Loa Loa (eye worm) hypothetical protein 0.0031 0.0062 0.0062
Schistosoma mansoni 6-phosphofructokinase 0.0115 0.0355 0.0352
Echinococcus multilocularis pyruvate kinase 0.0028 0.0051 0.0049
Trypanosoma cruzi oligopeptidase b 0.0229 0.075 0.2245
Entamoeba histolytica pyrophosphate-dependent phosphofructokinase 0.0031 0.0062 0.042
Trichomonas vaginalis Importin beta-1 subunit, putative 0.0022 0.0029 0.0266
Trypanosoma cruzi DNA topoisomerase II, putative 0.0045 0.0111 0.0325
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD2 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0023 0.0035 0.0321
Echinococcus multilocularis dna polymerase kappa 0.0104 0.0315 0.0313
Trichomonas vaginalis PIKK family atypical protein kinase 0.0021 0.0028 0.0258
Echinococcus granulosus fmrfamide receptor 0.0017 0.0012 0.001
Echinococcus multilocularis rhodopsin orphan GPCR 0.0017 0.0012 0.001
Loa Loa (eye worm) hypothetical protein 0.0017 0.0012 0.0012
Brugia malayi AKH receptor 0.0017 0.0012 0.0008
Brugia malayi jmjC domain containing protein 0.0062 0.0171 0.0167
Mycobacterium ulcerans two component sensor histidine kinase DevS 0.0045 0.0111 0.1068
Schistosoma mansoni tyrosine kinase 0.0166 0.0531 0.0528
Echinococcus multilocularis cadherin EGF LAG seven pass G type receptor 0.0143 0.0451 0.0449
Schistosoma mansoni biogenic amine receptor 0.0017 0.0012 0.0008
Trichomonas vaginalis PIKK family atypical protein kinase 0.0021 0.0028 0.0258
Echinococcus granulosus biogenic amine 5HT receptor 0.0017 0.0012 0.001
Trypanosoma cruzi hypothetical protein, conserved 0.0191 0.0616 0.1843
Schistosoma mansoni hypothetical protein 0.0143 0.0451 0.0447
Trichomonas vaginalis conserved hypothetical protein 0.0024 0.0038 0.0357
Schistosoma mansoni rab6-interacting 0.0042 0.0099 0.0096
Echinococcus multilocularis dihydrolipoamide dehydrogenase 0.0017 0.0014 0.0012
Brugia malayi Phosphatidylinositol 3- and 4-kinase family protein 0.0038 0.0086 0.0082
Brugia malayi 6-phosphofructokinase 0.0115 0.0355 0.0352
Mycobacterium tuberculosis Inositol-1-monophosphatase SuhB 0.0035 0.0076 0.0878
Leishmania major heat shock protein 83-1 0.0222 0.0726 0.2152
Schistosoma mansoni transient receptor potential channel 0.0092 0.0274 0.0271
Schistosoma mansoni heat shock protein 0.0222 0.0726 0.0723
Mycobacterium ulcerans extragenic suppressor protein SuhB 0.0039 0.009 0.0837
Loa Loa (eye worm) nuclear Hormone Receptor family member 0.0027 0.0048 0.0048
Brugia malayi hypothetical protein 0.0017 0.0012 0.0008
Toxoplasma gondii phosphofructokinase PFKII 0.0031 0.0062 0.0152
Echinococcus granulosus TRP transient receptor potential channel 0.0034 0.0073 0.0071
Brugia malayi GTP-binding nuclear protein RAN/TC4 0.002 0.0022 0.0019
Plasmodium falciparum phosphoglycerate kinase 0.0181 0.0582 0.7722
Echinococcus granulosus Basic leucine zipper bZIP transcription 0.0038 0.0087 0.0085
Echinococcus multilocularis Pyruvate dehydrogenase (lipoamide) kinase 0.0045 0.0111 0.0109
Schistosoma mansoni tyrosine kinase 0.0163 0.0521 0.0518
Leishmania major DNA polymerase eta, putative 0.0103 0.0311 0.0901
Trichomonas vaginalis dynamin, putative 0.0133 0.0418 0.421
Brugia malayi Transient-receptor-potential like protein 0.0034 0.0073 0.007
Echinococcus multilocularis rhodopsin orphan GPCR 0.0017 0.0012 0.001
Brugia malayi Bloom's syndrome protein homolog 0.0021 0.0027 0.0023
Loa Loa (eye worm) nuclear hormone receptor family member nhr-49 0.0027 0.0048 0.0048
Trichomonas vaginalis PIKK family atypical protein kinase 0.0021 0.0028 0.0258
Onchocerca volvulus 0.0017 0.0012 0.0006
Schistosoma mansoni chromobox protein-related (chromobox 1) (heterochromatin 1) 0.0024 0.0038 0.0034
Trichomonas vaginalis chromobox protein, putative 0.0024 0.0038 0.0357
Brugia malayi prolyl oligopeptidase family protein 0.0972 0.3331 0.3329
Giardia lamblia Heat shock protein HSP 90-alpha 0.0222 0.0726 0.731
Leishmania major phosphatidylinositol 3-kinase, putative 0.0038 0.0086 0.0223
Trichomonas vaginalis PIKK family atypical protein kinase 0.0038 0.0086 0.0841
Brugia malayi Phosphoglycerate kinase 0.0066 0.0184 0.0181
Entamoeba histolytica dynamin-1-like protein, putative 0.004 0.0094 0.0749
Mycobacterium ulcerans two component sensor histidine kinase TrcS 0.0045 0.0111 0.1068
Leishmania major heat shock protein 83-1 0.0222 0.0726 0.2152
Trichomonas vaginalis glucosylceramidase, putative 0.017 0.0544 0.5494
Echinococcus multilocularis chromobox protein 2 0.0024 0.0038 0.0036
Echinococcus granulosus nuclear receptor subfamily 1 group D 0.0014 0.0003 0.0002
Plasmodium vivax dihydrolipoyl dehydrogenase, apicoplast, putative 0.0017 0.0014 0.0035
Wolbachia endosymbiont of Brugia malayi phosphoglycerate kinase 0.0181 0.0582 1
Brugia malayi calcium-independent alpha-latrotoxin receptor 2, putative 0.0143 0.0451 0.0447
Trichomonas vaginalis glucosylceramidase, putative 0.0259 0.0854 0.8634
Toxoplasma gondii FATC domain-containing protein 0.0021 0.0028 0.005
Brugia malayi isocitrate dehydrogenase 0.0043 0.0104 0.0101
Leishmania major 4-coumarate:coa ligase-like protein 0.0023 0.0035 0.0069
Loa Loa (eye worm) hypothetical protein 0.1364 0.4696 0.4696
Loa Loa (eye worm) hypothetical protein 0.0103 0.0311 0.0311
Echinococcus multilocularis Polycystic kidney disease protein 0.0042 0.0099 0.0098
Loa Loa (eye worm) RNA binding protein 0.0115 0.0352 0.0352
Schistosoma mansoni myosin xvIII 0.0017 0.0012 0.0008
Echinococcus multilocularis lipoxygenase domain containing protein 0.0042 0.0099 0.0098
Loa Loa (eye worm) hypothetical protein 0.0052 0.0134 0.0134
Mycobacterium tuberculosis Probable phosphoglycerate kinase Pgk 0.0181 0.0582 0.7725
Loa Loa (eye worm) hypothetical protein 0.0017 0.0012 0.0012
Mycobacterium ulcerans glutaminase 0.0278 0.0921 1
Leishmania major phosphopantetheinyl transferase-like protein 0.0019 0.0022 0.003
Schistosoma mansoni jumonji/arid domain-containing protein 0.0062 0.0171 0.0167
Brugia malayi Dopamine receptor protein 1, putative (partial) 0.0017 0.0012 0.0008
Echinococcus granulosus serotonin receptor 0.0017 0.0012 0.001
Echinococcus multilocularis g protein coupled receptor 0.0017 0.0012 0.001
Loa Loa (eye worm) hypothetical protein 0.0017 0.0012 0.0012
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0017 0.0012 0.0008
Schistosoma mansoni thyrotropin-releasing hormone receptor 0.0017 0.0012 0.0008
Schistosoma mansoni chromodomain helicase DNA binding protein 0.0024 0.0038 0.0034
Loa Loa (eye worm) DRP-1 protein 0.0133 0.0418 0.0418
Loa Loa (eye worm) heat shock protein 90 0.0222 0.0726 0.0726
Plasmodium falciparum pyruvate kinase 0.0035 0.0077 0.0883
Loa Loa (eye worm) hypothetical protein 0.0023 0.0035 0.0035
Trichomonas vaginalis glucosylceramidase, putative 0.0179 0.0576 0.5816
Trichomonas vaginalis phosphoglycerate kinase, putative 0.0181 0.0582 0.5876
Brugia malayi hypothetical protein 0.012 0.037 0.0367
Trichomonas vaginalis glucosylceramidase, putative 0.0259 0.0854 0.8634
Mycobacterium ulcerans two component regulator - sensor kinase 0.0045 0.0111 0.1068
Brugia malayi Valyl-tRNA synthetase 0.0024 0.0038 0.0034
Trypanosoma brucei Heat shock protein 83, putative 0.0222 0.0726 0.2152
Echinococcus multilocularis rhodopsin orphan GPCR 0.0017 0.0012 0.001
Brugia malayi Flap endonuclease-1 0.0028 0.005 0.0046
Plasmodium falciparum apurinic/apyrimidinic endonuclease Apn1, putative 0.0081 0.0237 0.3047
Loa Loa (eye worm) hypothetical protein 0.0032 0.0064 0.0064
Mycobacterium tuberculosis Probable NADH dehydrogenase Ndh 0.0115 0.0352 0.4613
Trypanosoma brucei DNA polymerase kappa, putative 0.0059 0.016 0.0446
Mycobacterium tuberculosis Probable 6-phosphofructokinase PfkA (phosphohexokinase) (phosphofructokinase) 0.0115 0.0355 0.4654
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0298 0.0988 1
Toxoplasma gondii isocitrate dehydrogenase 0.0043 0.0104 0.0279
Schistosoma mansoni multiple ankyrin repeats single kh domain protein 0.0095 0.0285 0.0282
Trypanosoma cruzi apurinic/apyrimidinic endonuclease 0.0033 0.0069 0.0198
Schistosoma mansoni hypothetical protein 0.0143 0.0451 0.0447
Loa Loa (eye worm) prolyl oligopeptidase 0.289 1 1
Loa Loa (eye worm) hypothetical protein 0.0017 0.0014 0.0014
Loa Loa (eye worm) ImpB/MucB/SamB family protein 0.0076 0.0217 0.0217
Trichomonas vaginalis Clan SC, family S28, unassigned serine peptidase 0.0021 0.0027 0.0242
Echinococcus granulosus lysine specific demethylase 6a 0.0017 0.0012 0.001
Trichomonas vaginalis PIKK family atypical protein kinase 0.0038 0.0086 0.0841
Schistosoma mansoni hypothetical protein 0.0038 0.0087 0.0083
Mycobacterium ulcerans pyruvate kinase 0.0035 0.0077 0.0691
Brugia malayi latrophilin 2 splice variant baaae 0.0309 0.1027 0.1024
Schistosoma mansoni alpha-1 adrenergic receptor 0.0017 0.0012 0.0008
Wolbachia endosymbiont of Brugia malayi heat shock protein 90 0.0177 0.0569 0.9772
Trichomonas vaginalis conserved hypothetical protein 0.0035 0.0077 0.0753
Schistosoma mansoni hypothetical protein 0.0309 0.1027 0.1024
Leishmania major importin beta-1 subunit, putative 0.0022 0.0029 0.0052
Entamoeba histolytica myo-inositol monophosphatase, putative 0.0039 0.009 0.0709
Plasmodium falciparum isocitrate dehydrogenase [NADP], mitochondrial 0.0043 0.0104 0.1254
Plasmodium falciparum glutathione reductase 0.005 0.0128 0.1579
Trypanosoma cruzi isocitrate dehydrogenase [NADP], mitochondrial precursor, putative 0.0043 0.0104 0.0305
Trichomonas vaginalis chromobox protein, putative 0.0024 0.0038 0.0357
Loa Loa (eye worm) hypothetical protein 0.0014 0.0002 0.0002
Loa Loa (eye worm) hypothetical protein 0.0029 0.0053 0.0053
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0017 0.0012 0.0008
Plasmodium vivax DNA topoisomerase II, putative 0.0045 0.0111 0.1347
Trypanosoma brucei DNA polymerase kappa, putative 0.0104 0.0315 0.0914
Loa Loa (eye worm) hypothetical protein 0.0017 0.0012 0.0012
Loa Loa (eye worm) hypothetical protein 0.0017 0.0012 0.0012
Trypanosoma cruzi trypanothione reductase, putative 0.005 0.0128 0.0377
Chlamydia trachomatis DNA gyrase subunit B 0.0045 0.0111 0.1707
Brugia malayi ecdysteroid receptor 0.0027 0.0048 0.0044
Schistosoma mansoni peroxidasin 0.1364 0.4696 0.4695
Trypanosoma brucei ATP-dependent DEAD/H DNA helicase recQ, putative 0.0021 0.0027 0.0046
Plasmodium falciparum heat shock protein 90, putative 0.0091 0.027 0.3503
Trypanosoma cruzi mitochondrial DNA polymerase beta-PAK, putative 0.0045 0.0111 0.0324
Loa Loa (eye worm) isocitrate dehydrogenase 0.0043 0.0104 0.0104
Onchocerca volvulus DNA topoisomerase 2 homolog 0.0045 0.0111 0.0105
Trypanosoma cruzi hypothetical protein, conserved 0.0023 0.0035 0.0098
Echinococcus granulosus chromodomain helicase DNA binding protein 1 0.0024 0.0038 0.0036
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0017 0.0012 0.0008
Schistosoma mansoni amine GPCR 0.0017 0.0012 0.0008
Schistosoma mansoni hypothetical protein 0.0015 0.0007 0.0003
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0298 0.0988 1
Onchocerca volvulus Glucosylceramidase homolog 0.017 0.0544 0.0538
Plasmodium falciparum heat shock protein 90, putative 0.0091 0.027 0.3503
Schistosoma mansoni heat shock protein 0.0091 0.027 0.0267
Trichomonas vaginalis heat shock protein, putative 0.0222 0.0726 0.7341
Mycobacterium leprae PROBABLE 6-PHOSPHOFRUCTOKINASE PFKA (PHOSPHOHEXOKINASE) (PHOSPHOFRUCTOKINASE) 0.0115 0.0355 0.4576
Mycobacterium ulcerans DNA gyrase subunit B 0.0045 0.0111 0.1068
Trypanosoma brucei chrX additional, unordered contigs 0.0023 0.0035 0.0072
Trypanosoma cruzi DNA damage repair protein, putative 0.0023 0.0035 0.0098
Echinococcus granulosus tm gpcr rhodopsin 0.0017 0.0012 0.001
Schistosoma mansoni tyrosine kinase 0.0308 0.1025 0.1022
Brugia malayi heat shock protein 90 0.0222 0.0726 0.0723
Schistosoma mansoni coup transcription factor 0.0027 0.0048 0.0044
Loa Loa (eye worm) G-protein coupled receptor 0.0017 0.0012 0.0012
Loa Loa (eye worm) hypothetical protein 0.0017 0.0012 0.0012
Schistosoma mansoni rab geranylgeranyl transferase alpha subunit 0.0076 0.0217 0.0213
Trichomonas vaginalis 6-phosphofructokinase, putative 0.0031 0.0062 0.0602
Trichomonas vaginalis PIKK family atypical protein kinase 0.0038 0.0086 0.0841
Echinococcus multilocularis g-protein coupled receptor 0.0017 0.0012 0.001
Echinococcus granulosus netrin receptor unc 5 0.0015 0.0007 0.0005
Mycobacterium leprae Probable pyruvate kinase PykA 0.0035 0.0077 0.076
Echinococcus granulosus g protein linked acetylcholine receptor gar 2a 0.0017 0.0012 0.001
Loa Loa (eye worm) hypothetical protein 0.0017 0.0012 0.0012
Echinococcus multilocularis Dipeptidyl peptidase 9 0.0972 0.3331 0.333
Trichomonas vaginalis PIKK family atypical protein kinase 0.0038 0.0086 0.0841
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0027 0.0048 0.0044
Trypanosoma brucei hypothetical protein, conserved 0.0023 0.0035 0.0072
Echinococcus multilocularis short transient receptor potential channel 6 0.0061 0.0166 0.0164
Trypanosoma brucei prolyl oligopeptidase, putative 0.0229 0.075 0.2224
Brugia malayi RNA binding protein 0.0115 0.0352 0.0349
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0024 0.0038 0.0357
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0017 0.0012 0.0008
Echinococcus multilocularis tar DNA binding protein 0.0115 0.0352 0.035
Echinococcus granulosus hepatocyte nuclear factor 4 alpha 0.0027 0.0048 0.0046
Schistosoma mansoni chromobox protein 0.0024 0.0038 0.0034
Echinococcus granulosus RUN 0.0042 0.0099 0.0098
Echinococcus granulosus tachykinin peptides receptor 99D 0.0017 0.0012 0.001
Schistosoma mansoni adenoreceptor 0.0017 0.0012 0.0008
Brugia malayi RE15519p 0.0017 0.0012 0.0008
Schistosoma mansoni amine GPCR 0.0017 0.0012 0.0008
Trypanosoma cruzi PAB1-binding protein , putative 0.0045 0.0109 0.0318
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0298 0.0988 1
Trichomonas vaginalis PIKK family atypical protein kinase 0.0038 0.0086 0.0841
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0128 0.0399 0.0395
Trypanosoma cruzi phosphatidylinositol 3-kinase, putative 0.0021 0.0028 0.0076
Schistosoma mansoni hypothetical protein 0.0017 0.0012 0.0008
Plasmodium falciparum conserved Plasmodium protein, unknown function 0.0024 0.0038 0.0356
Echinococcus granulosus 6 phosphofructokinase 0.0115 0.0355 0.0353
Loa Loa (eye worm) pyruvate kinase 0.0035 0.0077 0.0077
Loa Loa (eye worm) nuclear hormone receptor family member nhr-1 0.0027 0.0048 0.0048
Entamoeba histolytica chromodomain-helicase-DNA-binding protein, putative 0.0024 0.0038 0.017
Echinococcus multilocularis allatostatin A receptor 0.0017 0.0012 0.001
Onchocerca volvulus 0.0017 0.0012 0.0006
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0017 0.0012 0.0008
Schistosoma mansoni chromodomain helicase DNA binding protein 0.0024 0.0038 0.0034
Loa Loa (eye worm) hypothetical protein 0.0309 0.1027 0.1027
Loa Loa (eye worm) latrophilin receptor protein 2 0.0143 0.0451 0.0451
Loa Loa (eye worm) gonadotropin-releasing hormone receptor 2 0.0017 0.0012 0.0012
Loa Loa (eye worm) hypothetical protein 0.0033 0.0067 0.0067
Entamoeba histolytica prolyl oligopeptidase family protein 0.0229 0.075 0.7536
Plasmodium falciparum DNA repair protein REV1, putative 0.0023 0.0035 0.0322
Echinococcus multilocularis Ankyrin 0.0015 0.0007 0.0005
Echinococcus multilocularis Lysosomal Pro X carboxypeptidase 0.039 0.131 0.1309
Trichomonas vaginalis ran, putative 0.002 0.0022 0.0195
Leishmania major dihydrolipoamide dehydrogenase, putative 0.0017 0.0014 0.0008
Plasmodium vivax AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.0033 0.0069 0.0773
Loa Loa (eye worm) animal heme peroxidase 0.1364 0.4696 0.4696
Echinococcus multilocularis lipoxygenase domain containing protein 0.0042 0.0099 0.0098
Brugia malayi Steroid receptor seven-up type 2 0.0027 0.0048 0.0044
Trypanosoma brucei peptidyl-prolyl cis-trans isomerase/rotamase, putative 0.0035 0.0074 0.0188
Loa Loa (eye worm) hypothetical protein 0.0017 0.0012 0.0012
Mycobacterium tuberculosis Two component sensor histidine kinase DevS 0.0045 0.0111 0.1356
Loa Loa (eye worm) jmjC domain-containing protein 0.0017 0.0012 0.0012
Echinococcus granulosus heat shock protein 0.0222 0.0726 0.0725
Trypanosoma cruzi PAS-domain containing phosphoglycerate kinase, putative 0.0066 0.0184 0.0545
Trichomonas vaginalis pyruvate kinase, putative 0.0035 0.0077 0.0752
Loa Loa (eye worm) hypothetical protein 0.0181 0.0582 0.0582
Schistosoma mansoni loxhd1 0.0042 0.0099 0.0096
Onchocerca volvulus 0.1364 0.4696 0.4693
Trypanosoma brucei heat shock protein, putative 0.0222 0.0726 0.2152
Entamoeba histolytica hypothetical protein 0.0024 0.0038 0.017
Brugia malayi jmjC domain containing protein 0.0017 0.0012 0.0008
Loa Loa (eye worm) hypothetical protein 0.0017 0.0012 0.0012
Trypanosoma brucei unspecified product 0.0097 0.0291 0.084
Echinococcus multilocularis Ataxin 2, N terminal,domain containing protein 0.002 0.0023 0.0022
Echinococcus granulosus pyruvate kinase 0.0018 0.0017 0.0015
Loa Loa (eye worm) hypothetical protein 0.0021 0.0027 0.0027
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0298 0.0988 1
Schistosoma mansoni hypothetical protein 0.0017 0.0011 0.0008
Trypanosoma brucei Phosphatidylinositol 3-kinase tor1 0.0038 0.0086 0.0223
Entamoeba histolytica exodeoxyribonuclease III, putative 0.0033 0.0069 0.0488
Trypanosoma brucei heat shock protein, putative 0.0222 0.0726 0.2152
Brugia malayi 6-phosphofructokinase 0.0115 0.0355 0.0352
Giardia lamblia Pyruvate kinase 0.0035 0.0077 0.0643
Entamoeba histolytica fructose-1,6-bisphosphate aldolase, putative 0.0298 0.0988 1
Brugia malayi MH2 domain containing protein 0.0107 0.0325 0.0321
Brugia malayi neuropeptide F receptor 0.0017 0.0012 0.0008
Loa Loa (eye worm) hypothetical protein 0.0017 0.0012 0.0012
Brugia malayi Doublecortin family protein 0.0042 0.0099 0.0096
Trichomonas vaginalis chromobox protein, putative 0.0024 0.0038 0.0357
Leishmania major acetoin dehydrogenase e3 component-like protein 0.0017 0.0014 0.0008
Brugia malayi Type III restriction enzyme, res subunit family protein 0.0024 0.0038 0.0034
Loa Loa (eye worm) phosphofructokinase 0.0115 0.0355 0.0355
Echinococcus granulosus neuropeptide s receptor 0.164 0.5654 0.5653
Trypanosoma brucei dihydrolipoamide dehydrogenase, point mutation 0.0017 0.0014 0.0008
Loa Loa (eye worm) intermediate filament tail domain-containing protein 0.0029 0.0053 0.0053
Echinococcus multilocularis neuropeptide receptor 0.0017 0.0012 0.001
Echinococcus granulosus serine:threonine protein kinase SMG1 0.0021 0.0028 0.0026
Toxoplasma gondii thioredoxin reductase 0.005 0.0128 0.0351
Schistosoma mansoni prolyl oligopeptidase (S09 family) 0.0229 0.075 0.0747
Echinococcus granulosus Chromobox protein 3 0.0024 0.0038 0.0036
Trichomonas vaginalis conserved hypothetical protein 0.0229 0.075 0.7583
Brugia malayi Melatonin receptor type 1A 0.0017 0.0012 0.0008
Toxoplasma gondii DNA topoisomerase 2, putative 0.0045 0.0111 0.03
Trichomonas vaginalis Clan SC, family S28, unassigned serine peptidase 0.0021 0.0027 0.0242
Brugia malayi Dopamine receptor 0.0017 0.0012 0.0008
Mycobacterium tuberculosis NAD(P)H quinone reductase LpdA 0.0127 0.0396 0.5214
Trichomonas vaginalis conserved hypothetical protein 0.0024 0.0038 0.0357
Trypanosoma brucei mitochondrial DNA polymerase beta-PAK 0.0152 0.0481 0.1415
Echinococcus granulosus thyrotropin releasing hormone receptor 0.0017 0.0012 0.001
Leishmania major GTP-binding protein, putative 0.0133 0.0418 0.1223
Trichomonas vaginalis dynamin, putative 0.0133 0.0418 0.421
Loa Loa (eye worm) animal heme peroxidase 0.1364 0.4696 0.4696
Trypanosoma cruzi hypothetical protein, conserved 0.0023 0.0035 0.0098
Trichomonas vaginalis PIKK family atypical protein kinase 0.0038 0.0086 0.0841
Brugia malayi jmjC domain containing protein 0.0062 0.0171 0.0167
Trichomonas vaginalis PIKK family atypical protein kinase 0.0038 0.0086 0.0841
Leishmania major heat shock protein 83-1 0.0222 0.0726 0.2152
Trichomonas vaginalis conserved hypothetical protein 0.0024 0.0038 0.0357
Loa Loa (eye worm) hypothetical protein 0.0017 0.0012 0.0012
Echinococcus multilocularis NADP dependent isocitrate dehydrogenase 0.0043 0.0104 0.0102
Trypanosoma cruzi importin beta-1 subunit, putative 0.0022 0.0029 0.0079
Mycobacterium tuberculosis Probable fructose-bisphosphate aldolase Fba 0.0145 0.0459 0.6064
Loa Loa (eye worm) hypothetical protein 0.0027 0.0048 0.0048
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0024 0.0038 0.0357
Trypanosoma brucei heat shock protein 84, putative 0.0091 0.027 0.0779
Trypanosoma brucei DNA polymerase kappa, putative 0.0059 0.016 0.0446
Brugia malayi Heterochromatin protein 1 0.0086 0.0253 0.025
Brugia malayi Phosphatidylinositol 3- and 4-kinase family protein 0.0021 0.0028 0.0025
Trypanosoma cruzi heat shock protein 85, putative 0.0222 0.0726 0.2173
Trichomonas vaginalis glucosylceramidase, putative 0.0259 0.0854 0.8634
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0027 0.0048 0.0046
Schistosoma mansoni prolyl oligopeptidase (S09 family) 0.0229 0.075 0.0747
Echinococcus multilocularis fmrfamide receptor 0.0017 0.0012 0.001
Leishmania major phosphoglycerate kinase C, glycosomal 0.0181 0.0582 0.1718
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0128 0.0399 0.0397
Trypanosoma brucei isocitrate dehydrogenase [NADP], mitochondrial precursor, putative 0.0043 0.0104 0.0279
Trichomonas vaginalis DNA polymerase IV / kappa, putative 0.0104 0.0315 0.3168
Leishmania major pyruvate kinase 0.0035 0.0077 0.0196
Echinococcus multilocularis biogenic amine (5HT) receptor 0.0017 0.0012 0.001
Plasmodium falciparum pyruvate kinase 2 0.0018 0.0017 0.0072
Trypanosoma brucei Dipeptidyl-peptidase 8-like, putative 0.0972 0.3331 1
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0024 0.0038 0.0357
Loa Loa (eye worm) hypothetical protein 0.0021 0.0027 0.0027
Echinococcus granulosus 7TM GPCR rhodopsin 0.0017 0.0012 0.001
Echinococcus multilocularis epidermal growth factor receptor 0.0308 0.1025 0.1023
Loa Loa (eye worm) heat shock protein 75 0.0091 0.027 0.027
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0017 0.0012 0.0008
Plasmodium falciparum ATP-dependent 6-phosphofructokinase 0.0031 0.0062 0.0684
Plasmodium vivax dynamin-like protein, putative 0.0133 0.0418 0.5498
Brugia malayi kinase, mitochondrial precursor 0.0045 0.0111 0.0108
Trypanosoma brucei DNA polymerase eta, putative 0.0103 0.0311 0.0901
Echinococcus granulosus lamin dm0 0.0029 0.0053 0.0052
Brugia malayi Tachykinin-like peptides receptor 99D 0.0017 0.0012 0.0008
Trypanosoma cruzi peptidyl-prolyl cis-trans isomerase 0.0035 0.0074 0.0214
Echinococcus granulosus ATP dependent DNA helicase Q5 0.0021 0.0027 0.0025
Trypanosoma brucei phosphoglycerate kinase, putative 0.0066 0.0184 0.052
Loa Loa (eye worm) hypothetical protein 0.0014 0.0003 0.0003
Echinococcus multilocularis pyruvate kinase 0.0035 0.0077 0.0075
Brugia malayi Blistered cuticle protein 3 0.1364 0.4696 0.4695
Loa Loa (eye worm) hypothetical protein 0.0017 0.0012 0.0012
Echinococcus multilocularis thyrotropin releasing hormone receptor 0.0017 0.0012 0.001
Schistosoma mansoni vav2 0.0015 0.0005 0.0002
Loa Loa (eye worm) hypothetical protein 0.0017 0.0012 0.0012
Echinococcus granulosus short transient receptor potential channel 6 0.0061 0.0166 0.0164
Trichomonas vaginalis phosphofructokinase, putative 0.0031 0.0062 0.0602
Leishmania major phosphoglycerate kinase B, cytosolic 0.0181 0.0582 0.1718
Onchocerca volvulus Heterochromatin protein 1 homolog 0.0057 0.0151 0.0145
Brugia malayi Pyruvate kinase, muscle isozyme 0.0035 0.0077 0.0073
Entamoeba histolytica peptidyl-prolyl cis-trans isomerase, putative 0.0035 0.0074 0.0544
Brugia malayi Calcitonin receptor-like protein seb-1 0.0452 0.1524 0.1521
Loa Loa (eye worm) hypothetical protein 0.0027 0.0048 0.0048
Echinococcus multilocularis nuclear factor of activated T cells 5 0.0078 0.0226 0.0224
Echinococcus granulosus microtubule associated protein 2 0.1435 0.4943 0.4942
Loa Loa (eye worm) hypothetical protein 0.0015 0.0005 0.0005
Giardia lamblia Pyrophosphate-fructose 6-phosphate 1-phosphotransferase alpha subunit 0.0031 0.0062 0.0492
Trypanosoma brucei dynamin-1-like protein 0.0133 0.0418 0.1223
Trichomonas vaginalis importin beta-1, putative 0.0022 0.0029 0.0266
Echinococcus multilocularis DNA (apurinic or apyrimidinic site) lyase 0.0033 0.0069 0.0067
Leishmania major trypanothione reductase 0.005 0.0128 0.0351
Treponema pallidum phosphoglycerate kinase 0.0181 0.0582 0.5828
Chlamydia trachomatis dihydrolipoyl dehydrogenase 0.0017 0.0014 0.0001
Loa Loa (eye worm) hypothetical protein 0.0015 0.0007 0.0007
Schistosoma mansoni pyruvate kinase 0.0035 0.0077 0.0073
Echinococcus granulosus L aminoadipate semialdehyde 0.0069 0.0195 0.0193
Echinococcus granulosus dynamin 0.0133 0.0418 0.0416
Mycobacterium tuberculosis Possible DNA-damage-inducible protein P DinP (DNA polymerase V) (pol IV 2) (DNA nucleotidyltransferase (DNA-directed)) 0.0083 0.0241 0.3116
Trichomonas vaginalis conserved hypothetical protein 0.0029 0.0056 0.0538
Echinococcus multilocularis dynamin 1 0.0144 0.0453 0.0452
Loa Loa (eye worm) hypothetical protein 0.0017 0.0012 0.0012
Trypanosoma brucei PAB1-binding protein , putative 0.0045 0.0109 0.0293
Wolbachia endosymbiont of Brugia malayi signal transduction histidine kinase and receiver 0.0045 0.0111 0.1706
Echinococcus multilocularis lamin dm0 0.0029 0.0053 0.0052
Loa Loa (eye worm) neuropeptide F receptor 0.0017 0.0012 0.0012
Loa Loa (eye worm) hypothetical protein 0.0045 0.0111 0.0111
Loa Loa (eye worm) hypothetical protein 0.0014 0.0003 0.0003
Echinococcus granulosus epidermal growth factor receptor 0.0308 0.1025 0.1023
Echinococcus granulosus chromobox protein 1 0.0086 0.0253 0.0251
Trichomonas vaginalis Importin beta-1 subunit, putative 0.0022 0.0029 0.0266
Plasmodium vivax dihydrolipoyl dehydrogenase, mitochondrial, putative 0.0017 0.0014 0.0035
Echinococcus multilocularis isocitrate dehydrogenase 0.0043 0.0104 0.0102
Schistosoma mansoni neuropeptide receptor 0.0017 0.0012 0.0008
Schistosoma mansoni ap endonuclease 0.0033 0.0069 0.0065
Echinococcus granulosus histone lysine methyltransferase setb 0.0032 0.0064 0.0062
Trichomonas vaginalis flap endonuclease-1, putative 0.0028 0.005 0.0478
Brugia malayi Nuclear hormone receptor-like 1 0.0027 0.0048 0.0044
Brugia malayi Serotonin receptor 0.0017 0.0012 0.0008
Loa Loa (eye worm) glutathione reductase 0.005 0.0128 0.0128
Onchocerca volvulus Peroxidasin homolog 0.1364 0.4696 0.4693
Toxoplasma gondii serine carboxypeptidase s28 protein 0.0021 0.0027 0.0045
Mycobacterium tuberculosis Probable peptidase 0.0229 0.075 1
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0024 0.0038 0.0357
Echinococcus multilocularis Jumonji, AT rich interactive domain 1B 0.0017 0.0012 0.001
Brugia malayi G-protein coupled receptor 0.0017 0.0012 0.0008
Trichomonas vaginalis glucosylceramidase, putative 0.0259 0.0854 0.8634
Brugia malayi Probable DNA topoisomerase II 0.0045 0.0111 0.0108
Trichomonas vaginalis PIKK family atypical protein kinase 0.0021 0.0028 0.0258
Leishmania major mitochondrial DNA topoisomerase II 0.0045 0.0111 0.03
Trypanosoma brucei DNA polymerase kappa, putative 0.0104 0.0315 0.0914
Echinococcus granulosus DNA topoisomerase 2 alpha 0.0045 0.0111 0.0109
Echinococcus multilocularis 6 phosphofructokinase 0.0115 0.0355 0.0353
Trypanosoma cruzi pyruvate kinase 2, putative 0.0035 0.0077 0.0223
Brugia malayi Phosphatidylinositol 3- and 4-kinase family protein 0.0038 0.0086 0.0082
Mycobacterium ulcerans hypothetical protein 0.0023 0.0035 0.0225
Trichomonas vaginalis mismatch repair protein Mlh1C (mutL homolog) 0.0045 0.0111 0.1099
Loa Loa (eye worm) hypothetical protein 0.0025 0.004 0.004
Echinococcus multilocularis ankyrin repeat and death domain containing protein 0.0015 0.0007 0.0005
Plasmodium vivax hypothetical protein, conserved 0.0024 0.0038 0.0356
Schistosoma mansoni ap endonuclease 0.0033 0.0069 0.0065
Echinococcus multilocularis DNA dependent protein kinase catalytic subunit 0.0545 0.1848 0.1846
Loa Loa (eye worm) hypothetical protein 0.0017 0.0014 0.0014
Trichomonas vaginalis mgm1, putative 0.0133 0.0418 0.421
Trichomonas vaginalis mercuric reductase, putative 0.0017 0.0014 0.0116
Mycobacterium ulcerans sugar phosphate isomerases/epimerases 0.0021 0.0028 0.0154
Toxoplasma gondii chromodomain helicase DNA binding protein CHD1/SWI2/SNF2 0.0024 0.0038 0.0079
Loa Loa (eye worm) hypothetical protein 0.0017 0.0014 0.0014
Mycobacterium leprae DIHYDROLIPOAMIDE DEHYDROGENASE LPD (LIPOAMIDE REDUCTASE (NADH)) (LIPOYL DEHYDROGENASE) (DIHYDROLIPOYL DEHYDROGENASE) (DIAPHORASE 0.0127 0.0396 0.5144
Schistosoma mansoni nuclear receptor 2DBD-gamma 0.0027 0.0048 0.0044
Trypanosoma cruzi DNA damage repair protein, putative 0.0023 0.0035 0.0098
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0032 0.0064 0.006
Schistosoma mansoni peroxidasin 0.1364 0.4696 0.4695
Leishmania major hypothetical protein, conserved 0.0045 0.0109 0.0293
Trichomonas vaginalis Clan SC, family S28, unassigned serine peptidase 0.0021 0.0027 0.0242
Loa Loa (eye worm) hypothetical protein 0.0017 0.0012 0.0012
Loa Loa (eye worm) nuclear hormone receptor family member nhr-40 0.0027 0.0048 0.0048
Schistosoma mansoni rab6-interacting 0.0042 0.0099 0.0096
Loa Loa (eye worm) hypothetical protein 0.0024 0.0038 0.0038
Echinococcus granulosus ecdysone induced protein 78C 0.0027 0.0048 0.0046
Entamoeba histolytica hypothetical protein 0.0021 0.0028 0.0069
Toxoplasma gondii pyruvate dehydrogenase complex subunit PDH-E3II 0.0017 0.0014 0.0008
Brugia malayi G-protein-linked acetylcholine receptor protein 2, putative 0.0017 0.0012 0.0008
Schistosoma mansoni neuropeptide receptor 0.0017 0.0012 0.0008
Trypanosoma cruzi Phosphatidylinositol 3-kinase tor1 0.0038 0.0086 0.0249
Entamoeba histolytica FKBP-rapamycin associated protein (FRAP), putative 0.0038 0.0086 0.0664
Schistosoma mansoni aminoadipate-semialdehyde dehydrogenase 0.0069 0.0195 0.0191
Mycobacterium ulcerans two component system membrane associated sensor kinase 0.0045 0.0111 0.1068
Echinococcus multilocularis arachidonate 5 lipoxygenase 0.0117 0.0361 0.036
Brugia malayi phosphofructokinase 0.0115 0.0355 0.0352
Entamoeba histolytica hypothetical protein 0.0024 0.0038 0.017
Schistosoma mansoni lipoxygenase 0.0042 0.0099 0.0096
Echinococcus multilocularis transcription factor Dp 1 0.0041 0.0095 0.0093
Leishmania major DNA polymerase kappa, putative,DNA polymerase IV, putative 0.0083 0.0241 0.0692
Toxoplasma gondii ATPase/histidine kinase/DNA gyrase B/HSP90 domain-containing protein 0.0045 0.0111 0.03
Trypanosoma brucei developmentally regulated phosphoprotein 0.0045 0.0111 0.03
Echinococcus granulosus lysine specific demethylase 5A 0.0062 0.0171 0.0169
Mycobacterium ulcerans hypothetical protein 0.0023 0.0035 0.0234
Echinococcus multilocularis RUN 0.0042 0.0099 0.0098
Echinococcus granulosus inositol monophosphatase 1 0.0039 0.009 0.0088
Onchocerca volvulus Chorion peroxidase homolog 0.1364 0.4696 0.4693
Echinococcus granulosus DNA dependent protein kinase catalytic subunit 0.0545 0.1848 0.1846
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0128 0.0399 0.0395
Loa Loa (eye worm) hypothetical protein 0.0021 0.0027 0.0027
Schistosoma mansoni inositol monophosphatase 0.0039 0.009 0.0087
Onchocerca volvulus 0.0017 0.0012 0.0006
Schistosoma mansoni hypothetical protein 0.0024 0.0038 0.0034
Trypanosoma cruzi GTP-binding nuclear protein rtb2, putative 0.002 0.0022 0.0058
Brugia malayi Dopamine receptor protein 2 0.0017 0.0012 0.0008
Schistosoma mansoni cellular tumor antigen P53 0.0049 0.0122 0.0119
Echinococcus multilocularis inositol monophosphatase 1 0.0039 0.009 0.0088
Brugia malayi Animal haem peroxidase family protein 0.1364 0.4696 0.4695
Schistosoma mansoni protein phosphatase 2C 0.0017 0.0012 0.0008
Toxoplasma gondii ImpB/MucB/SamB family protein 0.0023 0.0035 0.0072
Echinococcus multilocularis thioredoxin glutathione reductase 0.005 0.0128 0.0126
Brugia malayi Dynamin central region family protein 0.0133 0.0418 0.0414
Echinococcus multilocularis neuropeptides capa receptor 0.0017 0.0012 0.001
Trichomonas vaginalis dynamin, putative 0.0133 0.0418 0.421
Echinococcus granulosus dna polymerase kappa 0.0104 0.0315 0.0313
Loa Loa (eye worm) pyruvate kinase-PB 0.0025 0.004 0.004
Mycobacterium tuberculosis Probable nitrite reductase [NAD(P)H] large subunit [FAD flavoprotein] NirB 0.0115 0.0352 0.4613
Loa Loa (eye worm) 5-hydroxytryptamine 2C receptor 0.0017 0.0012 0.0012
Brugia malayi DNA-(Apurinic or apyrimidinic site) lyase 0.0081 0.0237 0.0233
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0027 0.0048 0.0044
Trichomonas vaginalis phosphofructokinase, putative 0.0115 0.0355 0.3573
Echinococcus multilocularis neuropeptide FF receptor 2 0.0017 0.0012 0.001
Toxoplasma gondii 4'-phosphopantetheinyl transferase domain-containing protein 0.0019 0.0022 0.003
Trypanosoma brucei importin beta-1 subunit, putative 0.0027 0.0047 0.0105
Plasmodium falciparum glutathione reductase 0.0017 0.0014 0.0035
Schistosoma mansoni endoplasmin 0.0222 0.0726 0.0723
Entamoeba histolytica fructose-1,6-bisphosphate aldolase, putative 0.0298 0.0988 1
Echinococcus multilocularis chromodomain helicase DNA binding protein 1 0.0024 0.0038 0.0036
Plasmodium vivax pyruvate kinase, putative 0.0035 0.0077 0.0883
Loa Loa (eye worm) TK/INSR protein kinase 0.0099 0.0299 0.0299
Echinococcus multilocularis serotonin receptor 0.0017 0.0012 0.001
Echinococcus multilocularis 0.0095 0.0284 0.0282
Trypanosoma cruzi phosphatidylinositol 3-related kinase, putative 0.0038 0.0086 0.0249
Trypanosoma brucei DNA polymerase kappa, putative 0.0104 0.0315 0.0914
Loa Loa (eye worm) hypothetical protein 0.0017 0.0012 0.0012
Echinococcus multilocularis NADP dependent isocitrate dehydrogenase 0.0043 0.0104 0.0102
Leishmania major dihydrolipoamide dehydrogenase, putative 0.0017 0.0014 0.0008
Echinococcus multilocularis rhodopsin orphan GPCR 0.0017 0.0012 0.001
Schistosoma mansoni amine GPCR 0.0017 0.0012 0.0008
Brugia malayi Animal haem peroxidase family protein 0.1364 0.4696 0.4695
Schistosoma mansoni RAR-like nuclear receptor 0.0027 0.0048 0.0044
Chlamydia trachomatis two component regulatory system sensor histidine kinase 0.0045 0.0111 0.1707
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0027 0.0048 0.0046
Toxoplasma gondii LsmAD domain-containing protein 0.0045 0.0109 0.0293
Loa Loa (eye worm) tyrosyl-DNA phosphodiesterase 0.007 0.0197 0.0197
Trypanosoma cruzi serine peptidase, clan SC, family S9A-like protein, putative 0.0229 0.075 0.2245
Echinococcus granulosus orexin receptor type 2 0.0017 0.0012 0.001
Schistosoma mansoni lipoxygenase 0.0117 0.0361 0.0358
Loa Loa (eye worm) hypothetical protein 0.0017 0.0012 0.0012
Echinococcus multilocularis pyruvate kinase 0.0018 0.0017 0.0015
Trypanosoma brucei DNA topoisomerase ii 0.0045 0.0111 0.03
Trichomonas vaginalis conserved hypothetical protein 0.0054 0.014 0.1392
Onchocerca volvulus 0.0033 0.0067 0.0061
Echinococcus multilocularis sex peptide receptor 0.0017 0.0012 0.001
Brugia malayi Animal haem peroxidase family protein 0.1364 0.4696 0.4695
Brugia malayi ORL1-like opioid receptor 0.0017 0.0012 0.0008
Trypanosoma cruzi putative prolyl carboxypeptidase, putative 0.0021 0.0027 0.0072
Schistosoma mansoni amine GPCR 0.0017 0.0012 0.0008
Echinococcus multilocularis endoplasmin 0.0177 0.0569 0.0567
Brugia malayi hypothetical protein 0.0042 0.0099 0.0096
Loa Loa (eye worm) hypothetical protein 0.0045 0.0111 0.0111
Trypanosoma cruzi GTP-binding nuclear protein rtb2, putative 0.002 0.0022 0.0058
Trypanosoma brucei DNA polymerase kappa, putative 0.0104 0.0315 0.0914
Brugia malayi hypothetical protein 0.0017 0.0012 0.0008
Trichomonas vaginalis myo inositol monophosphatase, putative 0.0039 0.009 0.0886
Schistosoma mansoni chromobox protein 0.0086 0.0253 0.025
Echinococcus granulosus epidermal growth factor receptor 0.0166 0.0531 0.053
Echinococcus granulosus phosphatidylinositol 3 and 4 kinase 0.0038 0.0086 0.0084
Brugia malayi DNA topoisomerase II, alpha isozyme 0.0045 0.0111 0.0108
Brugia malayi hypothetical protein 0.0743 0.2535 0.2533
Plasmodium vivax heat shock protein, putative 0.0091 0.027 0.3503
Brugia malayi Muscleblind-like protein 0.0152 0.0482 0.0479
Onchocerca volvulus Pyruvate kinase homolog 0.0035 0.0077 0.0071
Trypanosoma cruzi DNA polymerase kappa, putative 0.0104 0.0315 0.0938
Schistosoma mansoni neuropeptide F-like receptor 0.0017 0.0012 0.0008
Brugia malayi hypothetical protein 0.0017 0.0012 0.0008
Brugia malayi Protein cec-1. 0.0024 0.0038 0.0034
Schistosoma mansoni dihydrolipoamide dehydrogenase 0.0017 0.0014 0.0011
Toxoplasma gondii peptidylprolyl isomerase 0.0035 0.0074 0.0188
Trypanosoma cruzi dihydrolipoyl dehydrogenase, putative 0.0017 0.0014 0.0034
Echinococcus multilocularis FTZ F1 alpha 0.0027 0.0048 0.0046
Trypanosoma cruzi DNA polymerase kappa, putative 0.0104 0.0315 0.0938
Loa Loa (eye worm) MH2 domain-containing protein 0.0107 0.0325 0.0325
Trypanosoma cruzi trypanothione reductase, putative 0.0017 0.0014 0.0034
Brugia malayi Corticotropin releasing factor receptor 2 precursor, putative 0.0452 0.1524 0.1521
Leishmania major heat shock protein 83-1 0.0222 0.0726 0.2152
Mycobacterium ulcerans long-chain fatty-acid CoA ligase 0.0023 0.0035 0.0225
Trichomonas vaginalis dynamin, putative 0.0133 0.0418 0.421
Leishmania major oligopeptidase b 0.0229 0.075 0.2224
Brugia malayi Dopamine receptor protein 1 0.0017 0.0012 0.0008
Loa Loa (eye worm) blistered cuticle protein 3 0.1364 0.4696 0.4696
Trypanosoma brucei prolyl endopeptidase 0.0229 0.075 0.2224
Echinococcus multilocularis chromodomain helicase DNA binding protein 4 0.0024 0.0038 0.0036
Loa Loa (eye worm) glutaminase 0.0278 0.0921 0.0921
Loa Loa (eye worm) hypothetical protein 0.0017 0.0012 0.0012
Echinococcus multilocularis transcription factor eb 0.0186 0.0602 0.06
Treponema pallidum heat shock protein 90 0.0177 0.0569 0.5695
Chlamydia trachomatis holo [acyl-carrier protein] synthase 0.0019 0.0022 0.013
Echinococcus granulosus alpha 1A adrenergic receptor 0.0017 0.0012 0.001
Giardia lamblia Heat shock protein HSP 90-alpha 0.0177 0.0569 0.5695
Leishmania major 4-coumarate:coa ligase-like protein 0.0023 0.0035 0.0069
Trichomonas vaginalis endoplasmin, putative 0.0136 0.0428 0.4311
Treponema pallidum diphosphate--fructose-6-phosphate 1-phosphotransferase 0.0031 0.0062 0.0492
Echinococcus granulosus pyruvate kinase 0.0035 0.0077 0.0075
Echinococcus multilocularis Pyruvate dehydrogenase (lipoamide) kinase 0.0045 0.0111 0.0109
Loa Loa (eye worm) hypothetical protein 0.1364 0.4696 0.4696
Leishmania major 4-coumarate:coa ligase-like protein 0.0023 0.0035 0.0069
Leishmania major oligopeptidase B-like protein,serine peptidase, clan SC, family S9A-like protein 0.0229 0.075 0.2224
Plasmodium falciparum ataxin-2 like protein, putative 0.0045 0.0109 0.1316
Brugia malayi AMP-binding enzyme family protein 0.0023 0.0035 0.0031
Trypanosoma cruzi phosphoglycerate kinase, putative 0.0066 0.0184 0.0545
Loa Loa (eye worm) hypothetical protein 0.0021 0.0027 0.0027
Loa Loa (eye worm) hypothetical protein 0.0035 0.0077 0.0077
Trypanosoma brucei DNA polymerase kappa, putative 0.0059 0.016 0.0446
Trypanosoma cruzi DNA polymerase kappa, putative 0.0104 0.0315 0.0938
Echinococcus multilocularis pyruvate kinase 0.0018 0.0017 0.0015
Loa Loa (eye worm) hypothetical protein 0.0017 0.0012 0.0012
Brugia malayi Nuclear hormone receptor family member nhr-3 0.0027 0.0048 0.0044
Loa Loa (eye worm) 6-phosphofructokinase 0.0115 0.0355 0.0355
Echinococcus multilocularis neuropeptide receptor 0.0017 0.0012 0.001
Mycobacterium ulcerans long-chain-fatty-acid-CoA ligase 0.0023 0.0035 0.0225
Mycobacterium ulcerans phosphoglycerate kinase 0.0181 0.0582 0.6258
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0017 0.0012 0.0008
Mycobacterium ulcerans putative regultory protein 0.0045 0.0111 0.1068
Leishmania major flap endonuclease-1 (FEN-1), putative 0.0028 0.005 0.0115
Loa Loa (eye worm) unidentified vitellogenin-linked transcript protein 6 0.0017 0.0012 0.0012
Toxoplasma gondii pyruvate kinase PyK1 0.0035 0.0077 0.0196
Echinococcus multilocularis heat shock protein 0.0222 0.0726 0.0725
Echinococcus granulosus chromodomain helicase DNA binding protein 4 0.0024 0.0038 0.0036
Mycobacterium tuberculosis Probable isocitrate dehydrogenase [NADP] Icd1 (oxalosuccinate decarboxylase) (IDH) (NADP+-specific ICDH) (IDP) 0.0043 0.0104 0.1263
Treponema pallidum diphosphate--fructose-6-phosphate 1-phosphotransferase 0.0115 0.0355 0.3498
Mycobacterium tuberculosis Probable membrane NADH dehydrogenase NdhA 0.0115 0.0352 0.4613
Trichomonas vaginalis receptor histidine kinase, putative 0.0045 0.0111 0.1099
Loa Loa (eye worm) hypothetical protein 0.0027 0.0048 0.0048
Brugia malayi neuropeptide F receptor 0.0017 0.0012 0.0008
Loa Loa (eye worm) hypothetical protein 0.0014 0.0003 0.0003
Trypanosoma cruzi heat shock protein 85, putative 0.0222 0.0726 0.2173
Loa Loa (eye worm) jmjC domain-containing protein 0.0062 0.0171 0.0171
Schistosoma mansoni jumonji domain containing protein 0.0062 0.0171 0.0167
Giardia lamblia Thymus-specific serine protease precursor 0.0021 0.0027 0.0127
Echinococcus multilocularis muscleblind protein 1 0.0152 0.0482 0.0481
Echinococcus multilocularis rhodopsin orphan GPCR 0.0017 0.0012 0.001
Echinococcus granulosus flap endonuclease 1 0.0028 0.005 0.0048
Echinococcus granulosus arachidonate 5 lipoxygenase 0.0117 0.0361 0.036
Loa Loa (eye worm) endoplasmin 0.0222 0.0726 0.0726
Wolbachia endosymbiont of Brugia malayi exonuclease III 0.0033 0.0069 0.0961
Mycobacterium ulcerans two component sensor histidine kinase SenX3 0.0045 0.0111 0.1068
Schistosoma mansoni steroid hormone receptor ad4bp 0.0027 0.0048 0.0044
Trichomonas vaginalis conserved hypothetical protein 0.0024 0.0037 0.0344
Schistosoma mansoni ran 0.002 0.0022 0.0019
Echinococcus multilocularis dynamin 0.0133 0.0418 0.0416
Loa Loa (eye worm) hypothetical protein 0.0017 0.0012 0.0012
Echinococcus multilocularis Chromo domain 0.0024 0.0038 0.0036
Loa Loa (eye worm) hypothetical protein 0.1364 0.4696 0.4696
Echinococcus multilocularis peptide (allatostatin:somatostatin) 0.0017 0.0012 0.001
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0017 0.0012 0.0008
Schistosoma mansoni hypothetical protein 0.0143 0.0451 0.0447
Echinococcus granulosus snurportin 1 0.0285 0.0944 0.0942
Schistosoma mansoni phosphoglycerate kinase 0.0181 0.0582 0.0579
Mycobacterium tuberculosis Two component sensor kinase [second part] 0.0045 0.0111 0.1356
Schistosoma mansoni multiple ankyrin repeats single kh domain protein 0.0095 0.0285 0.0282
Entamoeba histolytica recQ family helicase, putative 0.0021 0.0027 0.0055
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0017 0.0014 0.0034
Trichomonas vaginalis Clan SC, family S28, unassigned serine peptidase 0.0021 0.0027 0.0242
Trichomonas vaginalis sensory transduction histidine kinase bacterial, putative 0.0045 0.0111 0.1099
Loa Loa (eye worm) phosphatidylinositol 3 0.0038 0.0086 0.0086
Plasmodium vivax thioredoxin reductase, putative 0.005 0.0128 0.1579
Brugia malayi Protein kinase domain containing protein 0.0099 0.0299 0.0296
Loa Loa (eye worm) hypothetical protein 0.0229 0.075 0.075
Entamoeba histolytica phosphoglycerate kinase, putative 0.0181 0.0582 0.5796
Loa Loa (eye worm) inositol-1 0.0039 0.009 0.009
Schistosoma mansoni retinoblastoma-binding protein 4 (rbbp4) 0.0015 0.0007 0.0004
Leishmania major DNA polymerase kappa, putative 0.0023 0.0035 0.0072
Schistosoma mansoni DNA polymerase eta 0.0103 0.0311 0.0308
Treponema pallidum chemotaxis histidine kinase (cheA) 0.0045 0.0111 0.0994
Onchocerca volvulus Prolyl endopeptidase homolog 0.0229 0.075 0.0744
Entamoeba histolytica hypothetical protein 0.0024 0.0038 0.017
Onchocerca volvulus 0.012 0.037 0.0364
Loa Loa (eye worm) hypothetical protein 0.1364 0.4696 0.4696
Echinococcus multilocularis heat shock protein 90 0.0177 0.0569 0.0567
Schistosoma mansoni DNA topoisomerase II 0.0045 0.0111 0.0108
Wolbachia endosymbiont of Brugia malayi DNA gyrase, topoisomerase II, B subunit, GyrB 0.0045 0.0111 0.1706
Trypanosoma brucei DNA polymerase kappa, putative 0.0104 0.0315 0.0914
Echinococcus multilocularis pyruvate kinase 0.0035 0.0077 0.0075
Echinococcus multilocularis musashi 0.0029 0.0053 0.0052
Mycobacterium leprae conserved hypothetical protein 0.0021 0.0028 0.0091
Trypanosoma brucei unspecified product 0.0052 0.0135 0.0372
Brugia malayi Associated with TFs and helicases family protein 0.0024 0.0038 0.0034
Echinococcus multilocularis heat shock protein 75 kDa, mitochondrial 0.0091 0.027 0.0269
Loa Loa (eye worm) hypothetical protein 0.0021 0.0028 0.0028
Brugia malayi DnaJ domain containing protein 0.0061 0.0167 0.0164
Brugia malayi follicle stimulating hormone receptor 0.0017 0.0012 0.0008
Echinococcus granulosus g protein coupled receptor 0.0017 0.0012 0.001
Loa Loa (eye worm) 3-hydroxyacyl-CoA dehydrogenase type II 0.0057 0.0151 0.0151
Echinococcus multilocularis lysine specific demethylase 6a 0.0017 0.0012 0.001
Echinococcus granulosus g protein linked acetylcholine receptor gar 2a 0.0017 0.0012 0.001
Echinococcus granulosus somatostatin receptor 0.0017 0.0012 0.001
Loa Loa (eye worm) hypothetical protein 0.0017 0.0012 0.0012
Loa Loa (eye worm) nuclear hormone receptor family member nhr-31 0.0027 0.0048 0.0048
Loa Loa (eye worm) TOPoisomerase family member 0.0045 0.0111 0.0111
Echinococcus granulosus PIK kinase FAT and Armadillo domain containing protein 0.0017 0.0011 0.0009
Brugia malayi Phosphoglycerate kinase 0.0181 0.0582 0.0579
Brugia malayi Serotonin receptor 0.0017 0.0012 0.0008
Brugia malayi cytoplasmic intermediate filament protein 0.0015 0.0007 0.0004
Schistosoma mansoni dipeptidyl-peptidase 9 (S09 family) 0.0972 0.3331 0.3329
Loa Loa (eye worm) hypothetical protein 0.0027 0.0048 0.0048
Echinococcus granulosus tm gpcr rhodopsin 0.0017 0.0012 0.001
Schistosoma mansoni tar DNA-binding protein 0.0115 0.0352 0.0349
Wolbachia endosymbiont of Brugia malayi membrane associated signal transduction histidine kinase 0.0045 0.0111 0.1706
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0027 0.0048 0.0046
Echinococcus multilocularis neuropeptide s receptor 0.164 0.5654 0.5653
Echinococcus multilocularis chromobox protein 1 0.0086 0.0253 0.0251
Schistosoma mansoni hypothetical protein 0.0017 0.0012 0.0008
Plasmodium vivax GTP-binding nuclear protein RAN/TC4, putative 0.002 0.0022 0.014
Toxoplasma gondii dynamin-related protein DRPB 0.0133 0.0418 0.1223
Schistosoma mansoni biogenic amine (5HT) receptor 0.0017 0.0012 0.0008
Leishmania major hypothetical protein, conserved 0.0045 0.0111 0.03
Mycobacterium tuberculosis holo-[acyl-carrier protein] synthase AcpS (holo-ACP synthase) (CoA:APO-[ACP]pantetheinephosphotransferase) (CoA:APO-[acyl-carrie 0.0019 0.0022 0.0144
Onchocerca volvulus Peroxidase homolog 0.1364 0.4696 0.4693
Echinococcus multilocularis alpha 1A adrenergic receptor 0.0017 0.0012 0.001
Trichomonas vaginalis sensory transduction histidine kinase, putative 0.0045 0.0111 0.1099
Entamoeba histolytica dynamin-like protein 0.0133 0.0418 0.4097
Brugia malayi 3-hydroxyacyl-CoA dehydrogenase type II 0.0065 0.018 0.0176
Brugia malayi Variant SH3 domain containing protein 0.0015 0.0005 0.0002
Trichomonas vaginalis PIKK family atypical protein kinase 0.0038 0.0086 0.0841
Trichomonas vaginalis PIKK family atypical protein kinase 0.0038 0.0086 0.0841
Toxoplasma gondii ATPase/histidine kinase/DNA gyrase B/HSP90 domain-containing protein 0.0045 0.0111 0.03
Schistosoma mansoni lysosomal Pro-Xaa carboxypeptidase (S28 family) 0.0021 0.0027 0.0023
Trichomonas vaginalis PIKK family atypical protein kinase 0.0038 0.0086 0.0841
Schistosoma mansoni prolyl oligopeptidase (S09 family) 0.0229 0.075 0.0747
Echinococcus multilocularis dro:myosuppressin receptor 0.0017 0.0012 0.001
Entamoeba histolytica Ran family GTPase 0.002 0.0022 0.0005
Leishmania major developmentally regulated phosphoprotein-like protein 0.0045 0.0111 0.03
Echinococcus granulosus lipoxygenase domain containing protein 0.0042 0.0099 0.0098
Plasmodium falciparum DNA topoisomerase VI, b subunit, putative 0.0045 0.0111 0.1347
Trichomonas vaginalis chromobox protein, putative 0.0057 0.0151 0.1503
Trypanosoma cruzi PAS-domain containing phosphoglycerate kinase, putative 0.0066 0.0184 0.0545
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0017 0.0012 0.001
Loa Loa (eye worm) prolyl oligopeptidase 0.0229 0.075 0.075
Toxoplasma gondii dynamin gtpase 0.0088 0.0259 0.0746
Schistosoma mansoni histamine-responsive GPCR (AAF21638) 0.0017 0.0012 0.0008
Echinococcus granulosus pyroglutamylated rfamide peptide receptor 0.0017 0.0012 0.001
Echinococcus granulosus Ankyrin repeat domain containing protein 0.0095 0.0285 0.0284
Echinococcus multilocularis dna polymerase eta 0.0103 0.0311 0.0309
Brugia malayi Peroxidasin 0.1364 0.4696 0.4695
Echinococcus multilocularis insulin receptor 0.0099 0.0299 0.0297
Plasmodium vivax apurinic/apyrimidinic endonuclease Apn1, putative 0.0081 0.0237 0.3047
Brugia malayi M-phase phosphoprotein, mpp8 0.012 0.037 0.0366
Echinococcus granulosus diuretic hormone 44 receptor GPRdih2 0.0143 0.0451 0.0449
Echinococcus granulosus 7tm_1 domain containing protein 0.0017 0.0012 0.001
Brugia malayi larval opioid receptor 0.0017 0.0012 0.0008
Chlamydia trachomatis fructose-6-phosphate phosphotransferase 0.0031 0.0062 0.0845
Onchocerca volvulus Peroxidase homolog 0.1364 0.4696 0.4693
Onchocerca volvulus 0.0023 0.0035 0.0029
Trichomonas vaginalis glucosylceramidase, putative 0.0259 0.0854 0.8634
Trypanosoma cruzi peptidyl-prolyl cis-trans isomerase 0.0035 0.0074 0.0214
Trypanosoma brucei serine peptidase, clan SC, family S9A-like protein 0.0229 0.075 0.2224
Onchocerca volvulus 0.0042 0.0099 0.0093
Trypanosoma brucei phosphatidylinositol 3-kinase, putative 0.0038 0.0086 0.0223
Loa Loa (eye worm) nuclear hormone receptor family member nhr-14 0.0027 0.0048 0.0048
Mycobacterium ulcerans fructose-bisphosphate aldolase 0.0145 0.0459 0.4905
Entamoeba histolytica dipeptidyl-peptidase, putative 0.0229 0.075 0.7536
Echinococcus granulosus short transient receptor potential channel 6 0.0061 0.0166 0.0164
Trypanosoma brucei flap endonuclease-1 (FEN-1), putative 0.0028 0.005 0.0115
Schistosoma mansoni hypothetical protein 0.002 0.0023 0.002
Mycobacterium leprae TWO COMPONENT SENSOR HISTIDINE KINASE PRRB 0.0045 0.0111 0.1229
Plasmodium vivax ataxin-2 like protein, putative 0.0045 0.0109 0.1316
Mycobacterium ulcerans short-chain type dehydrogenase/reductase 0.0065 0.018 0.1825
Echinococcus granulosus rhodopsin orphan GPCR 0.0017 0.0012 0.001
Mycobacterium ulcerans short-chain type dehydrogenase/reductase 0.0065 0.018 0.1825
Echinococcus granulosus nuclear factor of activated T cells 5 0.0078 0.0226 0.0224
Trypanosoma brucei target of rapamycin kinase 3, putative 0.0038 0.0086 0.0223
Mycobacterium leprae Probable fructose bisphosphate aldolase Fba 0.0145 0.0459 0.6006
Echinococcus granulosus dynamin 1 protein 0.0133 0.0418 0.0416
Loa Loa (eye worm) GTP-binding regulatory protein Gs alpha-S chain 0.0128 0.0399 0.0399
Brugia malayi Helix-loop-helix DNA-binding domain containing protein 0.0186 0.0602 0.0599
Onchocerca volvulus 0.0049 0.0122 0.0116
Trichomonas vaginalis PIKK family atypical protein kinase 0.0038 0.0086 0.0841
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0024 0.0038 0.0357
Trypanosoma cruzi oligopeptidase B-like protein, putative 0.0229 0.075 0.2245
Schistosoma mansoni biogenic amine receptor 0.0017 0.0012 0.0008
Trichomonas vaginalis chromobox protein, putative 0.0057 0.0151 0.1503
Trichomonas vaginalis Clan SC, family S28, unassigned serine peptidase 0.0021 0.0027 0.0242
Wolbachia endosymbiont of Brugia malayi 4'-phosphopantetheinyl transferase 0.0019 0.0022 0.0129
Brugia malayi hypothetical protein 0.0017 0.0012 0.0008
Loa Loa (eye worm) hypothetical protein 0.0014 0.0003 0.0003
Echinococcus granulosus muscleblind protein 0.0152 0.0482 0.0481
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0298 0.0988 1
Plasmodium vivax DNA gyrase subunit B, putative 0.0045 0.0111 0.1347
Loa Loa (eye worm) flap endonuclease-1 0.0028 0.005 0.005
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0017 0.0014 0.0034
Loa Loa (eye worm) hypothetical protein 0.0143 0.0451 0.0451
Brugia malayi G-protein coupled receptor 0.0017 0.0012 0.0008
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0032 0.0064 0.006
Schistosoma mansoni phosphatidylinositol 3-and 4-kinase 0.0038 0.0086 0.0082
Leishmania major 3-oxoacyl-(acyl-carrier protein) reductase, putative 0.0065 0.018 0.0506
Trichomonas vaginalis heat shock protein, putative 0.0177 0.0569 0.5745
Loa Loa (eye worm) hypothetical protein 0.0017 0.0012 0.0012
Trypanosoma cruzi tyrosyl-DNA Phosphodiesterase (Tdp1), putative 0.007 0.0197 0.0585
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0024 0.0038 0.0357
Echinococcus granulosus g protein coupled receptor 0.0017 0.0012 0.001
Mycobacterium leprae Probable two component sensor kinase MprB 0.0045 0.0111 0.1229
Echinococcus granulosus rhodopsin orphan GPCR 0.0017 0.0012 0.001
Treponema pallidum DNA gyrase, subunit B (gyrB) 0.0045 0.0111 0.0994
Loa Loa (eye worm) hypothetical protein 0.0024 0.0038 0.0038
Mycobacterium tuberculosis Conserved hypothetical protein 0.0169 0.0541 0.717
Trypanosoma cruzi serine carboxypeptidase S28, putative 0.0021 0.0027 0.0072
Mycobacterium ulcerans hypothetical protein 0.0021 0.0028 0.0154
Mycobacterium ulcerans sensor kinase from two component regulatory system 0.0045 0.0111 0.1068
Brugia malayi Endoplasmin precursor 0.0222 0.0726 0.0723
Giardia lamblia Alanyl dipeptidyl peptidase 0.0229 0.075 0.7554
Echinococcus granulosus bloom syndrome protein 0.0021 0.0027 0.0025
Trichomonas vaginalis heat shock protein, putative 0.0091 0.027 0.2714
Trichomonas vaginalis ap endonuclease, putative 0.0033 0.0069 0.0669
Toxoplasma gondii dipeptidyl peptidase iv (dpp iv) n-terminal region domain-containing protein 0.0972 0.3331 1
Trichomonas vaginalis PIKK family atypical protein kinase 0.0038 0.0086 0.0841
Schistosoma mansoni chromobox protein 0.0024 0.0038 0.0034
Trichomonas vaginalis DNA helicase recq, putative 0.0021 0.0027 0.0245
Plasmodium falciparum dihydrolipoyl dehydrogenase, mitochondrial 0.0017 0.0014 0.0035
Onchocerca volvulus Protein ultraspiracle homolog 0.0027 0.0048 0.0042
Trichomonas vaginalis PIKK family atypical protein kinase 0.0038 0.0086 0.0841
Echinococcus granulosus importin subunit beta 1 0.0027 0.0047 0.0045
Trypanosoma brucei FAT domain/Rapamycin binding domain/Phosphatidylinositol 3- and 4-kinase, putative 0.0024 0.0037 0.0075
Leishmania major prolyl oligopeptidase, putative,serine peptidase clan SC, family S9A, putative 0.0229 0.075 0.2224
Mycobacterium ulcerans protease II (oligopeptidase B), PtrB 0.0229 0.075 0.8112
Mycobacterium ulcerans DNA polymerase IV 0.0104 0.0315 0.3316
Trypanosoma brucei GTP-binding nuclear protein rtb2, putative 0.002 0.0022 0.0031
Mycobacterium tuberculosis Probable chaperone protein HtpG (heat shock protein) (HSP90 family protein) (high temperature protein G) 0.0177 0.0569 0.755
Echinococcus granulosus tm gpcr rhodopsin 0.0017 0.0012 0.001
Echinococcus multilocularis growth hormone secretagogue receptor type 1 0.0017 0.0012 0.001
Trypanosoma brucei DNA polymerase kappa, putative 0.0052 0.0134 0.0367
Leishmania major heat shock protein 83-1 0.0222 0.0726 0.2152
Echinococcus granulosus rhodopsin orphan GPCR 0.0017 0.0012 0.001
Mycobacterium leprae PROBABLE FATTY-ACID-CoA LIGASE FADD2 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) 0.0023 0.0035 0.0179
Leishmania major heat shock protein 83-1 0.0222 0.0726 0.2152
Trichomonas vaginalis rotamase, putative 0.0035 0.0077 0.0753
Trichomonas vaginalis protein kinase inhibitor, putative 0.0061 0.0167 0.1668
Trypanosoma brucei phosphatidylinositol 3-related kinase, putative 0.0038 0.0086 0.0223
Loa Loa (eye worm) hypothetical protein 0.1364 0.4696 0.4696
Loa Loa (eye worm) steroid hormone receptor 0.0027 0.0048 0.0048
Brugia malayi intermediate filament protein 0.0029 0.0053 0.005
Schistosoma mansoni FTZ-F1 nuclear receptor-like protein 0.0027 0.0048 0.0044
Brugia malayi glutaminase DH11.1 0.0278 0.0921 0.0918
Schistosoma mansoni opsin-like receptor 0.0017 0.0012 0.0008
Loa Loa (eye worm) hypothetical protein 0.0027 0.0048 0.0048
Schistosoma mansoni dynamin 0.0133 0.0418 0.0414
Plasmodium vivax pyruvate kinase 2, putative 0.0018 0.0017 0.0072
Echinococcus granulosus tyrosyl DNA phosphodiesterase 1 0.007 0.0197 0.0196
Trypanosoma brucei serine peptidase, Clan SC, Family S9B 0.0972 0.3331 1
Entamoeba histolytica phosphofructokinase, putative 0.0115 0.0355 0.3448
Schistosoma mansoni fkbp-rapamycin associated protein 0.0021 0.0028 0.0025
Echinococcus granulosus JmjC domain containing protein 4 0.0017 0.0012 0.001
Brugia malayi Pin1-type peptidyl-prolyl cis-trans isomerase, BmPin1 0.0035 0.0077 0.0074
Trichomonas vaginalis PIKK family atypical protein kinase 0.0038 0.0086 0.0841
Trypanosoma cruzi Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase, putative 0.0045 0.0111 0.0325
Toxoplasma gondii endonuclease IV APN 0.0081 0.0237 0.0678
Echinococcus granulosus transcription factor Dp 1 0.0041 0.0095 0.0093
Echinococcus granulosus jumonji domain containing 1A 0.0017 0.0012 0.001
Schistosoma mansoni tyrosine kinase 0.0099 0.0299 0.0296
Echinococcus multilocularis PIK kinase, FAT and Armadillo domain containing protein 0.0017 0.0011 0.0009
Treponema pallidum exodeoxyribonuclease (exoA) 0.0033 0.0069 0.056
Schistosoma mansoni DNA helicase recq1 0.0021 0.0027 0.0023
Trypanosoma cruzi serine peptidase, Clan SC, Family S9B 0.0972 0.3331 1
Entamoeba histolytica phosphofructokinase, putative 0.0115 0.0355 0.3448
Echinococcus multilocularis L aminoadipate semialdehyde 0.0069 0.0195 0.0193
Trichomonas vaginalis conserved hypothetical protein 0.0017 0.0011 0.0086
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0128 0.0399 0.0397
Echinococcus granulosus NADP dependent isocitrate dehydrogenase 0.0043 0.0104 0.0102
Trypanosoma cruzi DNA polymerase eta, putative 0.0051 0.0129 0.038
Echinococcus granulosus ankyrin repeat and death domain containing protein 0.0015 0.0007 0.0005
Loa Loa (eye worm) hypothetical protein 0.0042 0.0099 0.0099
Schistosoma mansoni dynamin 0.0144 0.0453 0.045
Mycobacterium ulcerans acyl-CoA synthetase 0.0023 0.0035 0.0225
Echinococcus granulosus neuropeptide Y receptor 0.0017 0.0012 0.001
Onchocerca volvulus 0.0017 0.0012 0.0006
Loa Loa (eye worm) hypothetical protein 0.0017 0.0012 0.0012
Brugia malayi hypothetical protein 0.0017 0.0012 0.0008
Plasmodium vivax phosphoglycerate kinase, putative 0.0181 0.0582 0.7722
Brugia malayi hypothetical protein 0.0017 0.0012 0.0008
Entamoeba histolytica dynamin-1-like protein, putative 0.0133 0.0418 0.4097
Schistosoma mansoni hypothetical protein 0.0061 0.0167 0.0164
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0298 0.0988 1
Loa Loa (eye worm) hypothetical protein 0.0014 0.0003 0.0003
Plasmodium falciparum dynamin-like protein 0.0133 0.0418 0.5498
Entamoeba histolytica hypothetical protein, conserved 0.0229 0.075 0.7536
Schistosoma mansoni hypothetical protein 0.0143 0.0451 0.0447
Echinococcus granulosus transient receptor potential ion channel A 0.0089 0.0264 0.0262
Onchocerca volvulus 0.0017 0.0012 0.0006
Schistosoma mansoni NADP-specific isocitrate dehydrogenase 0.0043 0.0104 0.0101
Trichomonas vaginalis prolylcarboxypeptidase, putative 0.0021 0.0027 0.0242
Schistosoma mansoni histamine h1 receptor 0.0017 0.0012 0.0008
Mycobacterium ulcerans epimerase 0.0021 0.0028 0.0154
Mycobacterium tuberculosis Two component sensor histidine kinase DosT 0.0045 0.0111 0.1356
Schistosoma mansoni polycystin 1-related 0.0042 0.0099 0.0096
Toxoplasma gondii acylaminoacyl-peptidase, putative 0.0229 0.075 0.2224
Loa Loa (eye worm) G-protein coupled receptor 0.0017 0.0012 0.0012
Trichomonas vaginalis phosphofructokinase, putative 0.0031 0.0062 0.0602
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0298 0.0988 1
Trichomonas vaginalis phosphofructokinase, putative 0.0031 0.0062 0.0602
Trichomonas vaginalis dynamin, putative 0.0133 0.0418 0.421
Toxoplasma gondii 'chromo' (CHRromatin Organization MOdifier) domain-containing protein 0.0024 0.0038 0.0079
Trypanosoma cruzi phosphoglycerate kinase, putative 0.0181 0.0582 0.174
Schistosoma mansoni hypothetical protein 0.0215 0.0701 0.0698
Brugia malayi Nuclear hormone receptor family member nhr-1 0.0027 0.0048 0.0044
Leishmania major lipophosphoglycan biosynthetic protein, putative,heat shock protein 90, putative,glucose regulated protein 94, putative 0.0177 0.0569 0.1679
Schistosoma mansoni retinoid-x-receptor (RXR) 0.0027 0.0048 0.0044
Plasmodium falciparum DNA topoisomerase 2 0.0045 0.0111 0.1347
Onchocerca volvulus Pyruvate kinase homolog 0.0035 0.0077 0.0071
Trypanosoma brucei DNA polymerase kappa, putative 0.0104 0.0315 0.0914
Echinococcus granulosus sex peptide receptor 0.0017 0.0012 0.001
Trichomonas vaginalis glucosylceramidase, putative 0.017 0.0544 0.5494
Loa Loa (eye worm) hypothetical protein 0.0017 0.0012 0.0012
Echinococcus multilocularis microtubule associated protein 2 0.1435 0.4943 0.4942
Loa Loa (eye worm) helicase 0.0024 0.0038 0.0038
Schistosoma mansoni thyroid hormone receptor 0.0027 0.0048 0.0044
Mycobacterium tuberculosis Two component sensor kinase MprB 0.0045 0.0111 0.1356
Loa Loa (eye worm) hypothetical protein 0.1364 0.4696 0.4696
Loa Loa (eye worm) hypothetical protein 0.0027 0.0048 0.0048
Mycobacterium tuberculosis Two component sensory transduction histidine kinase MtrB 0.0045 0.0111 0.1356
Loa Loa (eye worm) hypothetical protein 0.0144 0.0453 0.0453
Giardia lamblia GTOR 0.0038 0.0086 0.0734
Echinococcus granulosus G protein coupled 5 hydroxytryptamine receptor 0.0017 0.0012 0.001
Brugia malayi Hypothetical 29.7 kDa protein C05D11.5 in chromosome III 0.0021 0.0028 0.0025
Echinococcus multilocularis g protein linked acetylcholine receptor gar 2a 0.0017 0.0012 0.001
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0128 0.0399 0.0397
Echinococcus granulosus g protein coupled receptor 0.0017 0.0012 0.001
Onchocerca volvulus 0.0017 0.0012 0.0006
Echinococcus granulosus peroxidasin 0.1364 0.4696 0.4695
Loa Loa (eye worm) hypothetical protein 0.0017 0.0012 0.0012
Trypanosoma cruzi heat shock protein, putative 0.0091 0.027 0.0804
Entamoeba histolytica prolyl oligopeptidase family protein 0.0229 0.075 0.7536
Mycobacterium leprae PROBABLE CHAPERONE PROTEIN HTPG (HEAT SHOCK PROTEIN) (HSP90 FAMILY PROTEIN) (HIGH TEMPERATURE PROTEIN G) 0.0177 0.0569 0.7514
Giardia lamblia Phosphoglycerate kinase 0.0181 0.0582 0.5828
Trypanosoma brucei heat shock protein, putative 0.0222 0.0726 0.2152
Mycobacterium ulcerans dihydrolipoamide dehydrogenase 0.0017 0.0014 0.0001
Brugia malayi AMP-binding enzyme family protein 0.0023 0.0035 0.0031
Trypanosoma cruzi PAB1-binding protein , putative 0.0045 0.0109 0.0318
Trypanosoma brucei tyrosyl-DNA Phosphodiesterase (Tdp1), putative 0.007 0.0197 0.0559
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0024 0.0038 0.0357
Brugia malayi Protein kinase domain containing protein 0.0015 0.0007 0.0003
Toxoplasma gondii prolyl endopeptidase 0.0229 0.075 0.2224
Echinococcus granulosus rhodopsin orphan GPCR 0.0017 0.0012 0.001
Plasmodium vivax acyl-CoA synthetase, putative 0.0017 0.0014 0.0034
Entamoeba histolytica hypothetical protein 0.0038 0.0087 0.0672
Trichomonas vaginalis conserved hypothetical protein 0.0024 0.0038 0.0357
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0027 0.0048 0.0046
Trypanosoma brucei DNA topoisomerase II alpha, putative 0.0045 0.0111 0.03
Echinococcus multilocularis lamin 0.0029 0.0053 0.0052
Onchocerca volvulus 0.0017 0.0012 0.0006
Plasmodium vivax DNA repair protein REV1, putative 0.0023 0.0035 0.0322
Echinococcus granulosus rhodopsin orphan GPCR 0.0017 0.0012 0.001
Echinococcus granulosus Ataxin 2 N terminaldomain containing protein 0.002 0.0023 0.0022
Loa Loa (eye worm) variant SH3 domain-containing protein 0.0015 0.0005 0.0005
Brugia malayi Serine carboxypeptidase S28 family protein 0.0021 0.0027 0.0023
Echinococcus multilocularis hepatocyte nuclear factor 4 alpha 0.0027 0.0048 0.0046
Echinococcus granulosus 5'partial|histone lysine N methyltransferase SETDB2 0.0031 0.006 0.0058
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0027 0.0048 0.0044
Onchocerca volvulus Netrin receptor homolog 0.0015 0.0007 0.0001
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0024 0.0038 0.0357
Loa Loa (eye worm) hypothetical protein 0.0152 0.0482 0.0482
Echinococcus granulosus Pyruvate dehydrogenase lipoamide kinase 0.0045 0.0111 0.0109
Brugia malayi prolyl oligopeptidase family protein 0.0229 0.075 0.0747
Trichomonas vaginalis glucosylceramidase, putative 0.017 0.0544 0.5494
Schistosoma mansoni pyruvate dehydrogenase 0.0045 0.0111 0.0108
Leishmania major tyrosyl-DNA phosphodiesterase 1 0.007 0.0197 0.0559
Trypanosoma brucei phosphoglycerate kinase 0.0181 0.0582 0.1718
Schistosoma mansoni subfamily S9B unassigned peptidase (S09 family) 0.289 1 1
Plasmodium vivax endoplasmin, putative 0.0222 0.0726 0.9678
Trypanosoma cruzi ATP-dependent 6-phosphofructokinase, glycosomal 0.0115 0.0355 0.1058
Echinococcus granulosus neuropeptide receptor 0.0017 0.0012 0.001
Mycobacterium tuberculosis Probable short-chain type dehydrogenase/reductase 0.0065 0.018 0.2284
Trypanosoma cruzi apurinic/apyrimidinic endonuclease, putative 0.0033 0.0069 0.0198
Echinococcus granulosus intermediate filament protein 0.0029 0.0053 0.0052
Trypanosoma cruzi phosphoglycerate kinase, putative 0.0181 0.0582 0.174
Mycobacterium tuberculosis Possible two component sensor kinase 0.0045 0.0111 0.1356
Brugia malayi Dynamin 0.0144 0.0453 0.045
Onchocerca volvulus 0.0252 0.0828 0.0823
Loa Loa (eye worm) glutaminase 2 0.0278 0.0921 0.0921
Trypanosoma brucei DNA polymerase kappa, putative 0.0052 0.0134 0.0367
Trichomonas vaginalis glucosylceramidase, putative 0.017 0.0544 0.5494
Plasmodium falciparum thioredoxin reductase 0.005 0.0128 0.1579
Brugia malayi AMP-binding enzyme family protein 0.0023 0.0035 0.0031
Brugia malayi Uncoordinated protein 44 0.0015 0.0007 0.0003
Echinococcus multilocularis TRP (transient receptor potential) channel 0.0034 0.0073 0.0071
Trichomonas vaginalis PIKK family atypical protein kinase 0.0038 0.0086 0.0841
Leishmania major phosphatidylinositol 3-related kinase, putative 0.0038 0.0086 0.0223
Echinococcus granulosus hypothetical protein 0.0017 0.0012 0.001
Echinococcus multilocularis GPCR, family 2 0.0143 0.0451 0.0449
Loa Loa (eye worm) transcription factor SMAD2 0.0107 0.0325 0.0325
Trichomonas vaginalis phosphofructokinase, putative 0.0031 0.0062 0.0602
Echinococcus multilocularis histone lysine N methyltransferase SETMAR 0.0032 0.0064 0.0062
Loa Loa (eye worm) hypothetical protein 0.0023 0.0035 0.0035
Trypanosoma cruzi prolyl endopeptidase 0.0229 0.075 0.2245
Loa Loa (eye worm) hypothetical protein 0.0049 0.0122 0.0122
Trichomonas vaginalis conserved hypothetical protein 0.0021 0.0027 0.0242
Loa Loa (eye worm) hypothetical protein 0.012 0.037 0.037
Schistosoma mansoni family S28 unassigned peptidase (S28 family) 0.039 0.131 0.1307
Toxoplasma gondii non-specific serine/threonine protein kinase 0.0024 0.0037 0.0075
Leishmania major heat shock protein 83-1 0.0222 0.0726 0.2152
Echinococcus multilocularis jumonji domain containing 1A 0.0017 0.0012 0.001
Trypanosoma brucei DNA polymerase IV, putative 0.0097 0.0291 0.084
Echinococcus granulosus insulin receptor 0.0099 0.0299 0.0297
Loa Loa (eye worm) animal heme peroxidase 0.1364 0.4696 0.4696
Plasmodium falciparum DNA gyrase subunit B 0.0045 0.0111 0.1347
Schistosoma mansoni terminal deoxycytidyl transferase 0.0076 0.0217 0.0213
Schistosoma mansoni retinoic acid receptor RXR 0.0027 0.0048 0.0044
Onchocerca volvulus 0.0029 0.0053 0.0047
Loa Loa (eye worm) hypothetical protein 0.1364 0.4696 0.4696
Trypanosoma cruzi DNA polymerase eta, putative 0.0103 0.0311 0.0926
Plasmodium falciparum ADP-dependent DNA helicase RecQ 0.0021 0.0027 0.0207
Loa Loa (eye worm) hypothetical protein 0.0034 0.0073 0.0073
Brugia malayi sulfakinin receptor protein 0.0017 0.0012 0.0008
Entamoeba histolytica chromodomain-helicase-DNA-binding protein, putative 0.0024 0.0038 0.017
Leishmania major heat shock protein 83-1 0.0222 0.0726 0.2152
Echinococcus multilocularis geminin 0.0173 0.0554 0.0552
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0027 0.0048 0.0044
Echinococcus multilocularis prolyl endopeptidase 0.0229 0.075 0.0748
Echinococcus multilocularis Ankyrin repeat domain containing protein 0.0095 0.0285 0.0284
Schistosoma mansoni DNA polymerase IV / kappa 0.0023 0.0035 0.0032
Loa Loa (eye worm) hypothetical protein 0.0017 0.0012 0.0012
Schistosoma mansoni transient receptor potential channel 4 0.0092 0.0274 0.0271
Echinococcus multilocularis JmjC domain containing protein 4 0.0017 0.0012 0.001
Plasmodium falciparum heat shock protein 90 0.0222 0.0726 0.9678
Schistosoma mansoni hypothetical protein 0.0017 0.0012 0.0008
Entamoeba histolytica heat shock protein 90, putative 0.0222 0.0726 0.729
Schistosoma mansoni tar DNA-binding protein 0.0115 0.0352 0.0349
Giardia lamblia Pyruvate kinase 0.0018 0.0017 0.0028
Schistosoma mansoni transient receptor potential channel 0.0061 0.0166 0.0162
Loa Loa (eye worm) hypothetical protein 0.0017 0.0012 0.0012
Brugia malayi DNA gyrase/topoisomerase IV, A subunit family protein 0.0045 0.0111 0.0108
Trypanosoma brucei Alpha/beta hydrolase domain-containing protein 0.0229 0.075 0.2224
Echinococcus granulosus Dipeptidyl peptidase 9 0.0972 0.3331 0.333
Schistosoma mansoni growth hormone secretagogue receptor 0.0017 0.0012 0.0008
Echinococcus granulosus phd:f box containing protein 0.0017 0.0012 0.001
Schistosoma mansoni transcription factor LCR-F1 0.0038 0.0087 0.0083
Echinococcus multilocularis tachykinin peptides receptor 99D 0.0017 0.0012 0.001
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0298 0.0988 1
Onchocerca volvulus Neuropeptide F receptor homolog 0.0017 0.0012 0.0006
Echinococcus granulosus expressed protein 0.0035 0.0077 0.0075
Toxoplasma gondii 4'-phosphopantetheinyl transferase superfamily protein 0.0019 0.0022 0.003
Loa Loa (eye worm) TAR-binding protein 0.0115 0.0352 0.0352
Brugia malayi putative neuropeptide receptor NPR1 0.0017 0.0012 0.0008
Loa Loa (eye worm) hypothetical protein 0.0017 0.0012 0.0012
Trichomonas vaginalis Clan SC, family S33, methylesterase-like serine peptidase 0.0229 0.075 0.7583
Onchocerca volvulus 0.0017 0.0012 0.0006
Echinococcus multilocularis G protein coupled receptor 139 0.0017 0.0012 0.001
Mycobacterium ulcerans dihydrolipoamide dehydrogenase, LpdB 0.0017 0.0014 0.0001
Giardia lamblia Alanyl dipeptidyl peptidase 0.0229 0.075 0.7554
Echinococcus multilocularis COUP TF:Svp nuclear hormone receptor 0.0027 0.0048 0.0046
Echinococcus multilocularis insulin growth factor 1 receptor beta 0.0099 0.0299 0.0297
Echinococcus granulosus GTP binding nuclear protein Ran 0.002 0.0022 0.002
Schistosoma mansoni biogenic amine (5HT) receptor 0.0017 0.0012 0.0008
Trichomonas vaginalis Clan SC, family S9, acylaminoacyl-peptidase-like serine peptidase 0.0229 0.075 0.7583
Trichomonas vaginalis sensor histidine kinase, putative 0.0045 0.0111 0.1099
Echinococcus granulosus tumor protein p63 0.0331 0.1106 0.1104
Schistosoma mansoni inositol monophosphatase 0.0039 0.009 0.0087
Loa Loa (eye worm) doublecortin family protein 0.0042 0.0099 0.0099
Schistosoma mansoni microtubule-associated protein tau 0.1435 0.4943 0.4941
Trypanosoma brucei DNA polymerase kappa, putative 0.0104 0.0315 0.0914
Trichomonas vaginalis rotamase, putative 0.0035 0.0074 0.0724
Trichomonas vaginalis sensory transduction histidine kinase bacterial, putative 0.0045 0.0111 0.1099
Brugia malayi hypothetical protein 0.1364 0.4696 0.4695
Trichomonas vaginalis Clan SC, family S28, unassigned serine peptidase 0.0021 0.0027 0.0242
Leishmania major heat shock protein 83-1 0.0222 0.0726 0.2152
Echinococcus granulosus Lysosomal Pro X carboxypeptidase 0.039 0.131 0.1309
Echinococcus multilocularis atpase aaa+ type core atpase aaa type core 0.2291 0.7916 0.7916
Schistosoma mansoni hypothetical protein 0.0042 0.0099 0.0096
Trypanosoma cruzi heat shock protein 90, putative 0.0222 0.0726 0.2173
Brugia malayi Serine protease Z688.6 precursor 0.0021 0.0027 0.0023
Onchocerca volvulus 0.1364 0.4696 0.4693
Schistosoma mansoni flap endonuclease-1 0.0025 0.0041 0.0037
Mycobacterium ulcerans exodeoxyribonuclease III protein XthA 0.0033 0.0069 0.0602
Trichomonas vaginalis PIKK family atypical protein kinase 0.0038 0.0086 0.0841
Trypanosoma cruzi mitochondrial DNA polymerase beta-PAK, putative 0.0055 0.0145 0.0427
Mycobacterium tuberculosis Probable soluble pyridine nucleotide transhydrogenase SthA (STH) (NAD(P)(+) transhydrogenase [B-specific]) (nicotinamide nucleot 0.0017 0.0014 0.0045
Loa Loa (eye worm) hypothetical protein 0.0017 0.0012 0.0012
Echinococcus granulosus prolyl endopeptidase 0.0229 0.075 0.0748
Onchocerca volvulus 0.0017 0.0012 0.0006
Trichomonas vaginalis conserved hypothetical protein 0.0024 0.0038 0.0357
Trichomonas vaginalis conserved hypothetical protein 0.0024 0.0038 0.0357
Brugia malayi Nuclear hormone receptor family member nhr-14 0.0027 0.0048 0.0044
Loa Loa (eye worm) hypothetical protein 0.0017 0.0012 0.0012
Loa Loa (eye worm) hypothetical protein 0.0017 0.0012 0.0012
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0128 0.0399 0.0397
Trypanosoma brucei DNA topoisomerase II beta, putative 0.0045 0.0111 0.03
Trypanosoma brucei mitochondrial DNA polymerase beta 0.0321 0.1068 0.3183
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0024 0.0038 0.0357
Trichomonas vaginalis heat shock protein, putative 0.0177 0.0569 0.5745
Onchocerca volvulus Putative hydroxypyruvate isomerase 0.0021 0.0028 0.0022
Echinococcus granulosus dynamin 1 0.0144 0.0453 0.0452
Toxoplasma gondii heat shock protein 75, putative 0.0091 0.027 0.0779
Brugia malayi Latrophilin receptor protein 2 0.0143 0.0451 0.0447
Echinococcus multilocularis flap endonuclease 1 0.0028 0.005 0.0048
Trichomonas vaginalis interferon-induced GTP-binding protein mx, putative 0.0133 0.0418 0.421
Onchocerca volvulus 0.0017 0.0012 0.0006
Echinococcus multilocularis ATP dependent DNA helicase Q5 0.0021 0.0027 0.0025
Brugia malayi chromobox protein homolog 3 0.0054 0.014 0.0137
Plasmodium falciparum chromodomain-helicase-DNA-binding protein 1 homolog, putative 0.0024 0.0038 0.0356
Echinococcus multilocularis FTZ F1 nuclear receptor protein 0.0027 0.0048 0.0046
Echinococcus multilocularis histone lysine methyltransferase setb histone lysine methyltransferase eggless 0.0032 0.0064 0.0062
Brugia malayi Dynamin 0.0144 0.0453 0.045
Trichomonas vaginalis Clan SC, family S28, unassigned serine peptidase 0.0021 0.0027 0.0242
Schistosoma mansoni chromobox protein 0.0086 0.0253 0.025
Loa Loa (eye worm) jmjC domain-containing protein 0.0017 0.0012 0.0012
Trichomonas vaginalis phosphoglycerate kinase, putative 0.0181 0.0582 0.5876
Echinococcus granulosus 3 hydroxyacyl coenzyme A dehydrogenase type 2 0.0065 0.018 0.0178
Trypanosoma cruzi target of rapamycin kinase 3 0.0038 0.0086 0.0249
Chlamydia trachomatis phosphoglycerate kinase 0.0181 0.0582 1
Mycobacterium ulcerans two component sensor kinase MprB 0.0045 0.0111 0.1068
Loa Loa (eye worm) hypothetical protein 0.0017 0.0012 0.0012
Brugia malayi Furin-like cysteine rich region family protein 0.0308 0.1025 0.1022
Loa Loa (eye worm) hypothetical protein 0.0027 0.0048 0.0048
Brugia malayi Pyruvate kinase, M2 isozyme 0.0035 0.0077 0.0073
Echinococcus multilocularis ATP dependent DNA helicase Q1 0.0021 0.0027 0.0025
Mycobacterium leprae Probable phosphoglycerate kinase Pgk 0.0181 0.0582 0.7692
Loa Loa (eye worm) hypothetical protein 0.1364 0.4696 0.4696
Echinococcus granulosus lipoxygenase domain containing protein 0.0042 0.0099 0.0098
Loa Loa (eye worm) hypothetical protein 0.0743 0.2535 0.2535
Schistosoma mansoni 6-phosphofructokinase 0.0115 0.0355 0.0352
Brugia malayi G protein-coupled receptor 0.0017 0.0012 0.0008
Trypanosoma brucei heat shock protein, putative 0.0222 0.0726 0.2152
Toxoplasma gondii isocitrate dehydrogenase 0.0043 0.0104 0.0279
Loa Loa (eye worm) helix-loop-helix DNA-binding domain-containing protein 0.0186 0.0599 0.0599
Brugia malayi Unidentified vitellogenin-linked transcript protein 6, putative 0.0017 0.0012 0.0008
Schistosoma mansoni histone-lysine n-methyltransferase suv9 0.0056 0.0148 0.0145
Trypanosoma cruzi mitochondrial DNA polymerase beta-PAK, putative 0.0152 0.0481 0.1437
Treponema pallidum fructose-bisphosphate aldolase 0.0298 0.0988 1
Toxoplasma gondii target of rapamycin (TOR), putative 0.0038 0.0086 0.0223
Trypanosoma brucei unspecified product 0.0052 0.0135 0.0372
Schistosoma mansoni muscarinic acetylcholine (GAR) receptor 0.0017 0.0012 0.0008
Trichomonas vaginalis PIKK family atypical protein kinase 0.0021 0.0028 0.0258
Brugia malayi aminoadipate-semialdehyde dehydrogenase-phosphopantetheinyl transferase 0.0069 0.0195 0.0191
Trichomonas vaginalis PIKK family atypical protein kinase 0.0038 0.0086 0.0841
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0017 0.0012 0.001
Echinococcus multilocularis lysine specific demethylase 5A 0.0062 0.0171 0.0169
Onchocerca volvulus 0.0042 0.0099 0.0093
Loa Loa (eye worm) hypothetical protein 0.012 0.037 0.037
Loa Loa (eye worm) hypothetical protein 0.0017 0.0012 0.0012
Trypanosoma brucei heat shock protein, putative 0.0222 0.0726 0.2152
Entamoeba histolytica acyl-CoA synthetase, putative 0.0023 0.0035 0.0135
Plasmodium falciparum GTP-binding nuclear protein RAN/TC4 0.002 0.0022 0.014
Echinococcus granulosus terminal deoxycytidyl transferase rev1 0.0076 0.0217 0.0215
Leishmania major heat shock protein 83-1 0.0222 0.0726 0.2152
Giardia lamblia DINP protein human, muc B family 0.0083 0.0241 0.233
Plasmodium falciparum endoplasmin, putative 0.0136 0.0428 0.5633
Onchocerca volvulus 0.0017 0.0012 0.0006
Trypanosoma cruzi developmentally regulated phosphoprotein, putative 0.0045 0.0111 0.0325
Loa Loa (eye worm) hypothetical protein 0.0017 0.0014 0.0014
Trypanosoma cruzi mitochondrial DNA topoisomerase II, putative 0.0045 0.0111 0.0325
Giardia lamblia Endonuclease/Exonuclease/phosphatase 0.0033 0.0069 0.056
Entamoeba histolytica pyruvate kinase, putative 0.0025 0.004 0.0187
Brugia malayi Nuclear hormone receptor family member nhr-31 0.0027 0.0048 0.0044
Mycobacterium tuberculosis Probable pyruvate kinase PykA 0.0035 0.0077 0.0893
Trichomonas vaginalis glucosylceramidase, putative 0.0259 0.0854 0.8634
Trichomonas vaginalis hypothetical protein 0.0024 0.0038 0.0357
Onchocerca volvulus 0.0027 0.0048 0.0042
Plasmodium falciparum dihydrolipoyl dehydrogenase, apicoplast 0.0017 0.0014 0.0035
Mycobacterium ulcerans DNA polymerase IV 0.0104 0.0315 0.3316
Onchocerca volvulus 0.0017 0.0012 0.0006
Trypanosoma cruzi heat shock protein 90, putative 0.0131 0.041 0.1222
Schistosoma mansoni opsin-like receptor 0.0017 0.0012 0.0008
Plasmodium falciparum holo-[acyl-carrier-protein] synthase, putative 0.0019 0.0022 0.0134
Brugia malayi Animal haem peroxidase family protein 0.1364 0.4696 0.4695
Trichomonas vaginalis DNA polymerase eta, putative 0.0104 0.0315 0.3168
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0027 0.0048 0.0044
Toxoplasma gondii ImpB/MucB/SamB family protein 0.0051 0.0129 0.0355
Toxoplasma gondii hypothetical protein 0.0052 0.0134 0.0367
Trypanosoma cruzi hypothetical protein, conserved 0.0229 0.075 0.2245
Trypanosoma brucei dihydrolipoamide dehydrogenase 0.0017 0.0014 0.0008
Echinococcus granulosus Chromo domain 0.0024 0.0038 0.0036
Schistosoma mansoni ankyrin 23/unc44 0.0015 0.0007 0.0003
Toxoplasma gondii histone lysine methyltransferase SET/SUV39 0.0032 0.0064 0.0157
Schistosoma mansoni jumonji domain containing protein 0.0017 0.0012 0.0008
Leishmania major 2-oxoglutarate dehydrogenase, e3 component, lipoamidedehydrogenase-like protein 0.0017 0.0014 0.0008
Echinococcus granulosus endoplasmin 0.0177 0.0569 0.0567
Echinococcus multilocularis neuropeptide Y receptor 0.0017 0.0012 0.001
Trypanosoma cruzi heat shock protein 90, putative 0.0177 0.0569 0.1701
Schistosoma mansoni opsin-like receptor 0.0017 0.0012 0.0008
Loa Loa (eye worm) immunoglobulin I-set domain-containing protein 0.0015 0.0007 0.0007
Entamoeba histolytica Flap nuclease, putative 0.0028 0.005 0.0293
Giardia lamblia DNA damage repair protein 0.0023 0.0035 0.0218
Onchocerca volvulus Heterochromatin protein 1 homolog 0.0054 0.014 0.0134
Brugia malayi polk-prov protein 0.0052 0.0134 0.013
Trichomonas vaginalis conserved hypothetical protein 0.0024 0.0038 0.0357
Schistosoma mansoni peptide (FMRFamide/neurokinin-3)-like receptor 0.0017 0.0012 0.0008
Brugia malayi hypothetical protein 0.0017 0.0012 0.0008
Echinococcus multilocularis pyruvate kinase 0.0018 0.0017 0.0015
Schistosoma mansoni endoplasmin 0.0222 0.0726 0.0723
Schistosoma mansoni pyruvate kinase 0.0018 0.0017 0.0013
Schistosoma mansoni ran 0.002 0.0022 0.0019
Onchocerca volvulus Peroxidasin homolog 0.1364 0.4696 0.4693
Echinococcus multilocularis Chromobox protein 3 0.0024 0.0038 0.0036
Trichomonas vaginalis Clan SC, family S28, unassigned serine peptidase 0.0021 0.0027 0.0242
Schistosoma mansoni hypothetical protein 0.0173 0.0554 0.055
Toxoplasma gondii NADPH-glutathione reductase 0.0017 0.0014 0.0008
Schistosoma mansoni tyrosyl-DNA phosphodiesterase 0.007 0.0197 0.0194
Leishmania major ATP-dependent DEAD/H DNA helicase recQ, putative 0.0021 0.0027 0.0046
Loa Loa (eye worm) O-glycosyl hydrolase family 30 protein 0.0259 0.0854 0.0854
Trichomonas vaginalis PIKK family atypical protein kinase 0.0038 0.0086 0.0841
Echinococcus granulosus DNA apurinic or apyrimidinic site lyase 0.0033 0.0069 0.0067
Echinococcus granulosus cadherin EGF LAG seven pass G type receptor 0.0143 0.0451 0.0449
Trypanosoma brucei isocitrate dehydrogenase, putative 0.0043 0.0104 0.0279
Echinococcus granulosus chromobox protein 2 0.0024 0.0038 0.0036
Leishmania major heat shock protein, putative 0.0091 0.027 0.0779
Brugia malayi Nuclear hormone receptor family member nhr-49 0.0027 0.0048 0.0044
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0017 0.0012 0.0008
Brugia malayi Pre-SET motif family protein 0.0221 0.0722 0.0719
Loa Loa (eye worm) hypothetical protein 0.1364 0.4696 0.4696
Toxoplasma gondii HEAT repeat-containing protein 0.0027 0.0047 0.0105
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0024 0.0038 0.0357
Schistosoma mansoni tyrosine kinase 0.0099 0.0299 0.0296
Plasmodium vivax isocitrate dehydrogenase [NADP], mitochondrial, putative 0.0043 0.0104 0.1254
Schistosoma mansoni thyroid hormone receptor 0.0027 0.0048 0.0044
Mycobacterium ulcerans two component sensor histidine kinase PrrB 0.0045 0.0111 0.1068
Onchocerca volvulus 0.0017 0.0012 0.0006
Trypanosoma brucei heat shock protein 90, putative 0.0222 0.0726 0.2152
Trypanosoma cruzi 3-phosphoglycerate kinase, glycosomal 0.0066 0.0184 0.0545
Trypanosoma brucei phosphatidylinositol 4-kinase, putative 0.0038 0.0086 0.0223
Mycobacterium tuberculosis Possible two component system response sensor kinase membrane associated PhoR 0.0045 0.0111 0.1356
Brugia malayi ImpB/MucB/SamB family protein 0.0076 0.0217 0.0213
Loa Loa (eye worm) hypothetical protein 0.0017 0.0012 0.0012
Onchocerca volvulus Pyruvate kinase homolog 0.0035 0.0077 0.0071
Echinococcus multilocularis diuretic hormone 44 receptor GPRdih2 0.0143 0.0451 0.0449
Echinococcus granulosus chromobox protein 1 0.0086 0.0253 0.0251
Loa Loa (eye worm) hypothetical protein 0.0452 0.1524 0.1524
Brugia malayi nuclear receptor NHR-88 0.0027 0.0048 0.0044
Echinococcus granulosus death domain containing protein 0.0015 0.0007 0.0005
Schistosoma mansoni tyrosine kinase 0.0166 0.0531 0.0528
Echinococcus multilocularis expressed protein 0.0035 0.0077 0.0075
Echinococcus granulosus dihydrolipoamide dehydrogenase 0.0017 0.0014 0.0012
Mycobacterium tuberculosis Probable reductase 0.0115 0.0352 0.4613
Loa Loa (eye worm) hypothetical protein 0.1364 0.4696 0.4696
Loa Loa (eye worm) hypothetical protein 0.0014 0.0003 0.0003
Mycobacterium tuberculosis NADPH-dependent mycothiol reductase Mtr 0.005 0.0128 0.1588
Brugia malayi Serine protease Z688.6 precursor 0.0021 0.0027 0.0023
Echinococcus multilocularis serine:threonine protein kinase SMG1 0.0021 0.0028 0.0026
Trichomonas vaginalis DNA topoisomerase II, putative 0.0045 0.0111 0.1099
Trichomonas vaginalis phosphofructokinase, putative 0.0031 0.0062 0.0602
Echinococcus multilocularis acylamino acid releasing enzyme 0.0229 0.075 0.0748
Plasmodium vivax heat shock protein 90, putative 0.0091 0.027 0.3503
Wolbachia endosymbiont of Brugia malayi fructose-1,6-bisphosphatase 0.0039 0.009 0.1336
Mycobacterium tuberculosis DNA gyrase (subunit B) GyrB (DNA topoisomerase (ATP-hydrolysing)) (DNA topoisomerase II) (type II DNA topoisomerase) 0.0045 0.0111 0.1356
Trichomonas vaginalis PIKK family atypical protein kinase 0.0038 0.0086 0.0841
Echinococcus multilocularis snurportin 1 0.0285 0.0944 0.0942
Brugia malayi photoreceptor-specific nuclear receptor 0.0027 0.0048 0.0044
Echinococcus granulosus tar DNA binding protein 0.0115 0.0352 0.035
Brugia malayi Importin beta-1 subunit 0.0027 0.0047 0.0043
Entamoeba histolytica prolyl oligopeptidase family protein 0.0229 0.075 0.7536
Plasmodium falciparum acyl-CoA synthetase 0.0017 0.0014 0.0034
Brugia malayi Animal haem peroxidase family protein 0.1364 0.4696 0.4695
Schistosoma mansoni heat shock protein 0.0222 0.0726 0.0723
Mycobacterium leprae PROBABLE FATTY-ACID-CoA LIGASE FADD7 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) 0.0023 0.0035 0.0179
Schistosoma mansoni peptide (FMRFamide/somatostatin)-like receptor 0.0017 0.0012 0.0008
Mycobacterium ulcerans phosphopantetheinyl transferase, PptII 0.0019 0.0022 0.0081
Loa Loa (eye worm) 6-phosphofructokinase 0.0115 0.0355 0.0355
Entamoeba histolytica phosphatidylinositol3-kinaseTor2, putative 0.0038 0.0086 0.0664
Plasmodium vivax 6-phosphofructokinase, putative 0.0031 0.0062 0.0684
Onchocerca volvulus 0.0017 0.0012 0.0006
Trypanosoma brucei pyruvate kinase 1, putative 0.0035 0.0077 0.0196
Trichomonas vaginalis receptor histidine kinase, putative 0.0045 0.0111 0.1099
Trypanosoma brucei phosphatidylinositol kinase related protein, putative 0.0021 0.0028 0.005
Trypanosoma brucei DNA polymerase IV, putative 0.0104 0.0315 0.0914
Schistosoma mansoni acylaminoacyl-peptidase (S09 family) 0.0229 0.075 0.0747
Loa Loa (eye worm) hypothetical protein 0.0017 0.0012 0.0012
Mycobacterium leprae Probable two-component sensor kinase 0.0045 0.0111 0.1229
Brugia malayi gonadotropin-releasing hormone receptor 2 0.0017 0.0012 0.0008
Echinococcus multilocularis phosphoglycerate kinase 1 0.0181 0.0582 0.058
Loa Loa (eye worm) hypothetical protein 0.0017 0.0012 0.0012
Brugia malayi Tyrosyl-DNA phosphodiesterase family protein 0.007 0.0197 0.0194
Onchocerca volvulus Dopamine\/Ecdysteroid receptor homolog 0.0017 0.0012 0.0006
Echinococcus multilocularis somatostatin receptor 0.0017 0.0012 0.001
Echinococcus multilocularis importin subunit beta 1 0.0027 0.0047 0.0045
Brugia malayi steroid hormone receptor 0.0027 0.0048 0.0044
Brugia malayi jmjC domain containing protein 0.0017 0.0012 0.0008
Loa Loa (eye worm) melatonin receptor type 1A 0.0017 0.0012 0.0012
Loa Loa (eye worm) hypothetical protein 0.0017 0.0012 0.0012
Entamoeba histolytica hypothetical protein 0.0038 0.0087 0.0672
Loa Loa (eye worm) hypothetical protein 0.0186 0.0599 0.0599
Trypanosoma brucei inositol-1(or 4)-monophosphatase 1, putative 0.0039 0.009 0.0236
Trypanosoma cruzi dynamin-1-like protein 0.0133 0.0418 0.1246
Schistosoma mansoni tyrosine kinase 0.0163 0.0521 0.0518
Loa Loa (eye worm) hypothetical protein 0.0045 0.0111 0.0111
Toxoplasma gondii phosphoglycerate kinase PGKII 0.0181 0.0582 0.1718
Leishmania major ATP-dependent phosphofructokinase 0.0115 0.0355 0.1034
Echinococcus multilocularis pyroglutamylated rfamide peptide receptor 0.0017 0.0012 0.001
Plasmodium vivax glutathione reductase, putative 0.005 0.0128 0.1579
Trypanosoma cruzi Phosphatidylinositol 3-kinase tor2 0.0038 0.0086 0.0249
Echinococcus granulosus peptide allatostatin:somatostatin 0.0017 0.0012 0.001
Entamoeba histolytica hypothetical protein 0.0022 0.0029 0.0077
Leishmania major DNA polymerase eta, putative 0.0051 0.0129 0.0355
Trypanosoma cruzi dihydrolipoyl dehydrogenase, putative 0.0017 0.0014 0.0034
Echinococcus multilocularis thyroid hormone receptor alpha 0.0027 0.0048 0.0046
Trypanosoma brucei oligopeptidase b 0.0229 0.075 0.2224
Echinococcus granulosus geminin 0.0173 0.0554 0.0552
Onchocerca volvulus Heat shock protein 75 kDa, mitochondrial homolog 0.0091 0.027 0.0264
Leishmania major mitochondrial DNA polymerase beta 0.0321 0.1068 0.3183
Mycobacterium tuberculosis Probable dehydrogenase 0.0115 0.0352 0.4613
Leishmania major GTP-binding protein, putative 0.002 0.0022 0.0031
Echinococcus multilocularis rhodopsin orphan GPCR 0.0017 0.0012 0.001
Loa Loa (eye worm) neuropeptide F receptor 0.0017 0.0012 0.0012
Trichomonas vaginalis DNA helicase recq, putative 0.0021 0.0027 0.0245
Loa Loa (eye worm) follicle stimulating hormone receptor 0.0017 0.0012 0.0012
Entamoeba histolytica serine carboxypeptidase (S28) family protein 0.0021 0.0027 0.0053
Schistosoma mansoni DNA helicase recq5 0.0021 0.0027 0.0023
Trypanosoma brucei heat shock protein 90, putative 0.0222 0.0726 0.2152
Loa Loa (eye worm) hypothetical protein 0.0058 0.0155 0.0155
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0017 0.0012 0.0008
Trypanosoma brucei heat shock protein, putative 0.0222 0.0726 0.2152
Brugia malayi hypothetical protein 0.0017 0.0012 0.0008
Loa Loa (eye worm) nucleolar RNA-associated protein alpha 0.0285 0.0944 0.0944
Onchocerca volvulus 0.0069 0.0195 0.0189
Echinococcus multilocularis 3 hydroxyacyl coenzyme A dehydrogenase type 2 0.0065 0.018 0.0178
Schistosoma mansoni phd/f-box containing protein 0.0017 0.0012 0.0008
Trypanosoma brucei pyruvate kinase 1 0.0035 0.0077 0.0196
Trichomonas vaginalis PIKK family atypical protein kinase 0.0038 0.0086 0.0841
Entamoeba histolytica heat shock protein 90, putative 0.0222 0.0726 0.729
Loa Loa (eye worm) phosphatidylinositol 3 0.0038 0.0086 0.0086
Brugia malayi GnHR receptor homolog 0.0017 0.0012 0.0008
Trichomonas vaginalis phosphofructokinase, putative 0.0115 0.0355 0.3573
Trichomonas vaginalis heat shock protein, putative 0.0177 0.0569 0.5745
Echinococcus granulosus g-protein coupled receptor 0.0017 0.0012 0.001
Loa Loa (eye worm) TK/EGFR protein kinase 0.0308 0.1025 0.1025
Schistosoma mansoni netrin receptor unc5 0.0015 0.0007 0.0003
Loa Loa (eye worm) hypothetical protein 0.0045 0.0109 0.0109
Brugia malayi Thioredoxin reductase 0.005 0.0128 0.0125
Toxoplasma gondii ATP-dependent DNA helicase, RecQ family protein 0.0021 0.0027 0.0046
Loa Loa (eye worm) hypothetical protein 0.0017 0.0012 0.0012
Loa Loa (eye worm) ATP-dependent DNA helicase 0.0021 0.0027 0.0027
Plasmodium vivax heat shock protein 86, putative 0.0222 0.0726 0.9678
Loa Loa (eye worm) nuclear hormone receptor-like 1 0.0014 0.0003 0.0003
Mycobacterium tuberculosis Two component sensor histidine kinase PrrB 0.0045 0.0111 0.1356
Mycobacterium ulcerans flavoprotein disulfide reductase 0.0017 0.0014 0.0001
Echinococcus granulosus COUP TF:Svp nuclear hormone receptor 0.0027 0.0048 0.0046
Trichomonas vaginalis glucosylceramidase, putative 0.017 0.0544 0.5494
Brugia malayi Death domain containing protein 0.0015 0.0007 0.0003
Mycobacterium ulcerans heat shock protein 90 0.0177 0.0569 0.6115
Leishmania major heat shock protein 83-1 0.0222 0.0726 0.2152
Trichomonas vaginalis inositol monophosphatase, putative 0.0039 0.009 0.0886
Loa Loa (eye worm) hypothetical protein 0.0069 0.0195 0.0195
Leishmania major peptidyl-prolyl cis-trans isomerase/rotamase, putative,PPIase, putative 0.0035 0.0074 0.0188
Schistosoma mansoni hypothetical protein 0.0017 0.0012 0.0008
Brugia malayi hypothetical protein 0.0042 0.0099 0.0096
Onchocerca volvulus Putative DNA topoisomerase 2, mitochondrial 0.0045 0.0111 0.0105
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0017 0.0012 0.0008
Loa Loa (eye worm) hypothetical protein 0.0017 0.0012 0.0012
Brugia malayi RNA recognition motif domain containing protein 0.0115 0.0352 0.0349
Echinococcus multilocularis rhodopsin orphan GPCR 0.0017 0.0012 0.001
Leishmania major isocitrate dehydrogenase [NADP], mitochondrial precursor, putative 0.0043 0.0104 0.0279
Echinococcus multilocularis fmrfamide receptor 0.0017 0.0012 0.001
Echinococcus multilocularis neuropeptide receptor A26 0.164 0.5654 0.5653
Entamoeba histolytica deoxycytidyl transferase, putative 0.0076 0.0217 0.202
Schistosoma mansoni biogenic amine receptor 0.0017 0.0012 0.0008
Trypanosoma cruzi mitochondrial DNA topoisomerase II, putative 0.0045 0.0111 0.0325
Trichomonas vaginalis set domain proteins, putative 0.0251 0.0828 0.8373
Brugia malayi Pre-SET motif family protein 0.0032 0.0064 0.006
Echinococcus multilocularis chromobox protein 1 0.0086 0.0253 0.0251
Toxoplasma gondii heat shock protein HSP90 0.0222 0.0726 0.2152
Loa Loa (eye worm) hypothetical protein 0.0042 0.0099 0.0099
Trichomonas vaginalis Heterochromatin protein, putative 0.0024 0.0038 0.0357
Echinococcus multilocularis neuropeptides capa receptor 0.0017 0.0012 0.001
Loa Loa (eye worm) pigment dispersing factor receptor c 0.0452 0.1524 0.1524
Schistosoma mansoni ancient conserved domain protein 2 (cyclin m2) 0.0017 0.0012 0.0008
Loa Loa (eye worm) exodeoxyribonuclease III family protein 0.0033 0.0069 0.0069
Mycobacterium leprae PROBABLE NADH DEHYDROGENASE NDH 0.0115 0.0352 0.4534
Mycobacterium ulcerans hypothetical protein 0.0169 0.0541 0.5806
Loa Loa (eye worm) hypothetical protein 0.0017 0.0011 0.0011
Trypanosoma cruzi ATP-dependent DEAD/H DNA helicase recQ, putative 0.0021 0.0027 0.0072
Mycobacterium tuberculosis Conserved hypothetical protein 0.0076 0.0217 0.2787
Mycobacterium tuberculosis Conserved protein 0.0045 0.0111 0.1356
Trichomonas vaginalis Clan SC, family S28, unassigned serine peptidase 0.0021 0.0027 0.0242
Toxoplasma gondii dynamin-related protein DRPA 0.0133 0.0418 0.1223
Plasmodium falciparum ataxin-2 like protein, putative 0.0045 0.0109 0.1316
Trichomonas vaginalis prolylcarboxypeptidase, putative 0.0021 0.0027 0.0242
Plasmodium vivax 6-phosphofructokinase, putative 0.0031 0.0062 0.0684
Loa Loa (eye worm) hypothetical protein 0.0017 0.0012 0.0012
Trichomonas vaginalis chromobox protein, putative 0.0086 0.0253 0.2539
Loa Loa (eye worm) nuclear hormone receptor family member nhr-41 0.0027 0.0048 0.0048
Loa Loa (eye worm) pre-SET domain-containing protein family protein 0.0221 0.0722 0.0722
Trypanosoma brucei ATP-dependent 6-phosphofructokinase, glycosomal 0.0115 0.0355 0.1034
Echinococcus granulosus Lysosomal Pro X carboxypeptidase 0.0021 0.0027 0.0025
Echinococcus multilocularis 7TM GPCR, rhodopsin 0.0017 0.0012 0.001
Schistosoma mansoni tyrosine kinase 0.0163 0.0521 0.0518
Trichomonas vaginalis myo inositol monophosphatase, putative 0.0039 0.009 0.0886
Trichomonas vaginalis PIKK family atypical protein kinase 0.0024 0.0037 0.0344
Trypanosoma brucei hypothetical protein, conserved 0.0019 0.0022 0.003
Trypanosoma cruzi phosphoglycerate kinase, putative 0.0066 0.0184 0.0545
Mycobacterium leprae possible inositol monophosphatase SubH (IMPase) (inositol-1-phosphatase) (I-1-Pase ). 0.0035 0.0076 0.0745
Trichomonas vaginalis dynamin, putative 0.0133 0.0418 0.421
Schistosoma mansoni photoreceptor-specific nuclear receptor related 0.0027 0.0048 0.0044
Toxoplasma gondii ATP-dependent DNA helicase, RecQ family protein 0.0021 0.0027 0.0046
Trypanosoma cruzi mitochondrial DNA polymerase beta, putative 0.0321 0.1068 0.3201
Toxoplasma gondii 'chromo' (CHRromatin Organization MOdifier) domain-containing protein 0.0024 0.0038 0.0079
Trypanosoma brucei DNA polymerase kappa, putative 0.0083 0.0241 0.0692
Schistosoma mansoni transient receptor potential channel 0.0061 0.0166 0.0163
Schistosoma mansoni peptide (allatostatin)-like receptor 0.0017 0.0012 0.0008
Entamoeba histolytica phosphofructokinase, putative 0.0115 0.0355 0.3448
Brugia malayi jmjC domain containing protein 0.0017 0.0012 0.0008
Entamoeba histolytica DNA topoisomerase II, putative 0.0045 0.0111 0.0926
Echinococcus granulosus neuropeptide FF receptor 2 0.0017 0.0012 0.001
Echinococcus granulosus dipeptidyl aminopeptidaseprotein 0.289 1 1

Activities

Activity type Activity value Assay description Source Reference
IC50 (binding) = 4 nM Inhibition of hepatitis c virus Non structural protein 3 protease/Non structural protein 4A protease ChEMBL. 11212109
IC50 (binding) = 4 nM Inhibition of hepatitis c virus Non structural protein 3 protease/Non structural protein 4A protease ChEMBL. 11212109

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
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External resources for this compound

No external resources registered for this compound

Bibliographic References

1 literature reference was collected for this gene.

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