Detailed information for compound 403825

Basic information

Technical information
  • Name: Unnamed compound
  • MW: 1283.33 | Formula: C76H88I2N2
  • H donors: 0 H acceptors: 0 LogP: 15.44 Rotable bonds: 6
    Rule of 5 violations (Lipinski): 2
  • SMILES: CCCCC1[N+](C)(C)CC23C41C1C5C6C4=C4C7C8C6C6C9C5C5C%10C1C1C3C3C%11C2C4C2C7C4C7=C8C86C(CCCC)[N+](CC68C8C9C5C5C9C%10C1C1C3C3C%10C%11C2C2C4C4C7C6C6C8C5C5C9C1C3C1C(C%102)C4C6C51)(C)C.[I-].[I-]
  • InChi: 1S/C76H42N2.2HI/c1-7-9-11-15-75-69-57-45-33-23-19-21-17-18-22-20-24-31-39-27(20)25(17)37-29(21)41(33)53(57)65-49(37)51(39)67(73(65,75)13-77(15,3)4)55-43(31)36-46-34(24)42-30(22)38-26(18)28(19)40-32(23)44-35(45)48-60-56(44)68-52(40)50(38)66-54(42)58(46)70-62-47(36)59(55)71(75)63(61(48)69)64(62)72(60)76(70)16(12-10-8-2)78(5,6)14-74(66,68)76;;/h15-16,47,56-57,62,68-69H,7-14H2,1-6H3;2*1H/q+2;;/p-2
  • InChiKey: CYQAHGYKINKILD-UHFFFAOYSA-L  


Substructure search Similarity search

Network

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Synonyms

No synonyms found for this compound

Targets

Known targets for this compound

No curated genes were found associated with this compound

Predicted pathogen targets for this compound

By orthology
No druggable targets predicted by orthology data
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Leishmania major fk506-binding protein 1-like protein 0.1789 0.9992 1
Loa Loa (eye worm) hypothetical protein 0.0268 0.1409 0.141
Brugia malayi AMP-binding enzyme family protein 0.0025 0.0037 0.0037
Trypanosoma cruzi hypothetical protein, conserved 0.0039 0.0119 0.0119
Trichomonas vaginalis D-aminoacylase, putative 0.0039 0.0119 0.0119
Schistosoma mansoni sodium-dependent neurotransmitter transporter 0.004 0.0123 0.0123
Echinococcus multilocularis sodium dependent neurotransmitter transporter 0.004 0.0123 0.0123
Trichomonas vaginalis ribonuclease H1, putative 0.0027 0.0047 0.0048
Treponema pallidum sodium- and chloride- dependent transporter 0.0236 0.1229 0.123
Mycobacterium ulcerans hypothetical protein 0.0246 0.1286 0.1287
Loa Loa (eye worm) hypothetical protein 0.004 0.0123 0.0123
Echinococcus granulosus cyclin dependent kinase 5 activator 1 0.0268 0.1409 0.1409
Giardia lamblia FKBP-type peptidyl-prolyl cis-trans isomerase 0.0246 0.1286 0.1287
Brugia malayi jmjC domain containing protein 0.0032 0.008 0.008
Loa Loa (eye worm) hypothetical protein 0.0032 0.008 0.008
Loa Loa (eye worm) hypothetical protein 0.0096 0.0436 0.0436
Mycobacterium ulcerans fusion of enoyl-CoA hydratase, EchA21 and lipase, LipE 0.0039 0.0119 0.0119
Giardia lamblia Kinase, CMGC CDK 0.0045 0.0152 0.0152
Entamoeba histolytica cell division protein kinase 2, putative 0.0045 0.0152 0.0152
Loa Loa (eye worm) hypothetical protein 0.0039 0.0119 0.0119
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0021 0.0015 0.0015
Entamoeba histolytica acyl-CoA synthetase, putative 0.0025 0.0037 0.0037
Loa Loa (eye worm) hypothetical protein 0.0039 0.0119 0.0119
Leishmania major cell division related protein kinase 2,cdc2-related kinase 0.0045 0.0152 0.0152
Trichomonas vaginalis D-aminoacylase, putative 0.0039 0.0119 0.0119
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0021 0.0015 0.0015
Schistosoma mansoni retinoid-x-receptor (RXR) 0.0021 0.0015 0.0015
Toxoplasma gondii peptidyl-prolyl cis-trans isomerase, FKBP-type domain-containing protein 0.0246 0.1286 1
Loa Loa (eye worm) jmjC domain-containing protein 0.0032 0.008 0.008
Brugia malayi FKBP-type peptidyl-prolyl cis-trans isomerase-12, BmFKBP-12 0.1789 0.9992 1
Schistosoma mansoni tar DNA-binding protein 0.0066 0.0271 0.0271
Schistosoma mansoni tar DNA-binding protein 0.0066 0.0271 0.0271
Trypanosoma brucei DNA repair and recombination helicase protein PIF7 0.0034 0.0087 0.0087
Brugia malayi hypothetical protein 0.0024 0.0035 0.0035
Trichomonas vaginalis penicillin-binding protein, putative 0.0039 0.0119 0.0119
Loa Loa (eye worm) FKBP-type peptidyl-prolyl cis-trans isomerase-33 0.0246 0.1286 0.1287
Echinococcus granulosus jumonji domain containing 1A 0.0032 0.008 0.008
Loa Loa (eye worm) hypothetical protein 0.0147 0.0724 0.0725
Schistosoma mansoni sodium-dependent amino acid transporter 0.004 0.0123 0.0123
Trypanosoma cruzi PAB1-binding protein , putative 0.0024 0.0035 0.0035
Loa Loa (eye worm) hypothetical protein 0.0119 0.0568 0.0568
Leishmania major PIF1 helicase-like protein, putative,DNA repair and recombination protein, mitochondrial precursor, putative 0.0034 0.0087 0.0087
Echinococcus granulosus serotonin transporter 0.0236 0.1229 0.1229
Plasmodium vivax hypothetical protein, conserved 0.004 0.0123 0.0123
Loa Loa (eye worm) hypothetical protein 0.0128 0.0621 0.0621
Echinococcus multilocularis protein patched 0.0041 0.0128 0.0128
Loa Loa (eye worm) serotonin transporter b 0.0236 0.1229 0.123
Leishmania major ribonuclease H1, putative 0.0027 0.0047 0.0048
Giardia lamblia FKBP-type peptidyl-prolyl cis-trans isomerase 0.0246 0.1286 0.1287
Trichomonas vaginalis fk506-binding protein, putative 0.0246 0.1286 0.1287
Schistosoma mansoni serine/threonine protein kinase 0.0045 0.0152 0.0152
Plasmodium falciparum ataxin-2 like protein, putative 0.0024 0.0035 0.0035
Loa Loa (eye worm) hypothetical protein 0.0021 0.0015 0.0015
Echinococcus multilocularis Transcription factor, JmjC domain containing protein 0.0121 0.0582 0.0582
Plasmodium falciparum ataxin-2 like protein, putative 0.0024 0.0035 0.0035
Mycobacterium tuberculosis Probable lipase LipD 0.0039 0.0119 0.0905
Toxoplasma gondii peptidyl-prolyl cis-trans isomerase, FKBP-type domain-containing protein 0.0246 0.1286 1
Loa Loa (eye worm) nuclear hormone receptor family member nhr-31 0.0021 0.0015 0.0015
Trypanosoma brucei macrophage infectivity potentiator, precursor, putative 0.0246 0.1286 0.1287
Trichomonas vaginalis conserved hypothetical protein 0.0041 0.0128 0.0128
Loa Loa (eye worm) hypothetical protein 0.0021 0.0015 0.0015
Echinococcus multilocularis peptidyl prolyl cis trans isomerase FKBP4 0.179 1 1
Brugia malayi Sodium:neurotransmitter symporter family protein 0.004 0.0123 0.0123
Trichomonas vaginalis conserved hypothetical protein 0.0246 0.1286 0.1287
Trypanosoma cruzi PAB1-binding protein , putative 0.0024 0.0035 0.0035
Loa Loa (eye worm) hypothetical protein 0.0024 0.0035 0.0035
Schistosoma mansoni retinoic acid receptor RXR 0.0021 0.0015 0.0015
Loa Loa (eye worm) hypothetical protein 0.0032 0.008 0.008
Echinococcus multilocularis hepatocyte nuclear factor 4 alpha 0.0021 0.0015 0.0015
Echinococcus granulosus Jumonji AT rich interactive domain 1B 0.0032 0.008 0.008
Mycobacterium ulcerans hypothetical protein 0.0025 0.0037 0.0037
Mycobacterium leprae Probable lipase LipE 0.0039 0.0119 0.0656
Echinococcus multilocularis phd:f box containing protein 0.0032 0.008 0.008
Leishmania major peptidyl-prolyl cis-trans isomerase, macrophage infectivity potentiator precursor, putative 0.0246 0.1286 0.1287
Brugia malayi Sodium:neurotransmitter symporter family protein 0.004 0.0123 0.0123
Trichomonas vaginalis peptidylprolyl isomerase, putative 0.1789 0.9992 1
Brugia malayi jmjC domain containing protein 0.0032 0.008 0.008
Mycobacterium ulcerans long-chain-fatty-acid--CoA ligase 0.0025 0.0037 0.0037
Echinococcus multilocularis FK506 binding protein 8, 38 kDa 0.0248 0.1294 0.1294
Loa Loa (eye worm) hypothetical protein 0.0246 0.1286 0.1287
Trypanosoma brucei ingi protein (ORF1) 0.0029 0.006 0.006
Entamoeba histolytica cell division protein kinase 2, putative 0.0045 0.0152 0.0152
Brugia malayi CHE-14 protein 0.0041 0.0128 0.0128
Schistosoma mansoni niemann-pick C1 (NPC1) 0.0097 0.0444 0.0444
Brugia malayi Nuclear hormone receptor family member nhr-3 0.0021 0.0015 0.0015
Schistosoma mansoni patched 1 0.0041 0.0128 0.0128
Plasmodium vivax hypothetical protein, conserved 0.0039 0.0119 0.0119
Schistosoma mansoni norepinephrine/norepinephrine transporter 0.004 0.0123 0.0123
Schistosoma mansoni tar DNA-binding protein 0.0066 0.0271 0.0271
Loa Loa (eye worm) hypothetical protein 0.0039 0.0119 0.0119
Entamoeba histolytica acyl-coA synthetase, putative 0.0025 0.0037 0.0037
Loa Loa (eye worm) Sodium:neurotransmitter symporter family protein 0.004 0.0123 0.0123
Schistosoma mansoni hypothetical protein 0.0033 0.0084 0.0084
Leishmania major 4-coumarate:coa ligase-like protein 0.0025 0.0037 0.0037
Loa Loa (eye worm) jmjC domain-containing protein 0.0032 0.008 0.008
Toxoplasma gondii Sodium:neurotransmitter symporter family protein 0.004 0.0123 0.0957
Brugia malayi RNase H family protein 0.0027 0.0047 0.0048
Trypanosoma cruzi peptidyl-prolyl cis-trans isomerase, putative 0.1789 0.9992 1
Schistosoma mansoni coup transcription factor 0.0021 0.0015 0.0015
Trypanosoma cruzi ferric reductase transmembrane protein, putative 0.0033 0.0084 0.0084
Trypanosoma cruzi ribonuclease H1, putative 0.0027 0.0047 0.0048
Onchocerca volvulus 0.0039 0.0119 0.0821
Mycobacterium tuberculosis Probable chain -fatty-acid-CoA ligase FadD13 (fatty-acyl-CoA synthetase) 0.0025 0.0037 0.0282
Mycobacterium tuberculosis Possible conserved lipoprotein LpqK 0.0039 0.0119 0.0905
Loa Loa (eye worm) nuclear hormone receptor family member nhr-1 0.0021 0.0015 0.0015
Trypanosoma cruzi C-8 sterol isomerase, putative 0.0719 0.3953 0.3956
Chlamydia trachomatis peptidyl-prolyl cis-trans isomerase 0.0246 0.1286 1
Giardia lamblia Rrm3p helicase 0.0034 0.0087 0.0087
Echinococcus granulosus peptidyl prolyl cis trans isomerase FKBP1A 0.1789 0.9992 0.9992
Trypanosoma cruzi cdc2-related kinase 1 0.0045 0.0152 0.0152
Loa Loa (eye worm) hypothetical protein 0.0119 0.0568 0.0568
Loa Loa (eye worm) hypothetical protein 0.0025 0.0037 0.0037
Schistosoma mansoni nuclear hormone receptor nor-1/nor-2 0.0021 0.0015 0.0015
Giardia lamblia 70 kDa peptidylprolyl isomerase, putative 0.1789 0.9992 1
Brugia malayi Nuclear hormone receptor family member nhr-49 0.0021 0.0015 0.0015
Onchocerca volvulus 0.0039 0.0119 0.0821
Echinococcus multilocularis Niemann Pick C1 protein 0.0137 0.0667 0.0667
Loa Loa (eye worm) solute carrier family 6 member 4 0.0236 0.1229 0.123
Mycobacterium tuberculosis Probable esterase/lipase LipP 0.0039 0.0119 0.0905
Loa Loa (eye worm) hypothetical protein 0.0033 0.0084 0.0084
Brugia malayi Nuclear hormone receptor-like 1 0.0021 0.0015 0.0015
Leishmania major hypothetical protein, conserved 0.0032 0.008 0.008
Schistosoma mansoni norepinephrine/norepinephrine transporter 0.0236 0.1229 0.1229
Echinococcus multilocularis sodium and chloride dependent glycine 0.004 0.0123 0.0123
Mycobacterium tuberculosis Probable esterase LipL 0.0039 0.0119 0.0905
Leishmania major ferric reductase, putative 0.0033 0.0084 0.0084
Mycobacterium tuberculosis Probable trigger factor (TF) protein Tig 0.0246 0.1286 0.9775
Echinococcus granulosus beta LACTamase domain containing family member 0.0039 0.0119 0.0119
Entamoeba histolytica peptidyl-prolyl cis-trans isomerase, FKBP-type , putative 0.0246 0.1286 0.1286
Loa Loa (eye worm) abnormal chemotaxis protein 14 0.0041 0.0128 0.0128
Onchocerca volvulus 0.0246 0.1286 1
Onchocerca volvulus Huntingtin homolog 0.0119 0.0568 0.435
Echinococcus multilocularis thyroid hormone receptor alpha 0.0021 0.0015 0.0015
Schistosoma mansoni hypothetical protein 0.004 0.012 0.012
Brugia malayi jmjC domain containing protein 0.0121 0.0582 0.0582
Trypanosoma brucei ingi protein (ORF1) 0.0029 0.006 0.006
Schistosoma mansoni RAR-like nuclear receptor 0.0021 0.0015 0.0015
Trypanosoma cruzi cdc2-related kinase 1 0.0045 0.0152 0.0152
Loa Loa (eye worm) hypothetical protein 0.0145 0.0715 0.0716
Echinococcus multilocularis Niemann Pick C1 protein 0.0096 0.0436 0.0436
Schistosoma mansoni ubiquitously transcribed sex (X/Y) chromosome tetratricopeptide repeat protein-related 0.0034 0.0087 0.0087
Plasmodium vivax JmjC domain containing protein 0.0032 0.008 0.008
Toxoplasma gondii hypothetical protein 0.004 0.0123 0.0957
Brugia malayi RNase H family protein 0.0027 0.0047 0.0048
Loa Loa (eye worm) nuclear hormone receptor family member nhr-40 0.0021 0.0015 0.0015
Loa Loa (eye worm) nuclear hormone receptor family member nhr-41 0.0021 0.0015 0.0015
Trypanosoma cruzi hypothetical protein, conserved 0.0039 0.0119 0.0119
Trichomonas vaginalis conserved hypothetical protein 0.0034 0.0087 0.0087
Loa Loa (eye worm) hypothetical protein 0.004 0.0123 0.0123
Leishmania major PIF1 helicase-like protein, putative,DNA repair and recombination protein, mitochondrial precursor, putative 0.0034 0.0087 0.0087
Brugia malayi RNA binding protein 0.0066 0.0271 0.0272
Leishmania major C-8 sterol isomerase-like protein 0.0719 0.3953 0.3956
Loa Loa (eye worm) CMGC/CDK/CDK5 protein kinase 0.0045 0.0152 0.0152
Toxoplasma gondii hypothetical protein 0.004 0.0123 0.0957
Brugia malayi photoreceptor-specific nuclear receptor 0.0021 0.0015 0.0015
Echinococcus granulosus lysine specific demethylase 6a 0.0032 0.008 0.008
Echinococcus multilocularis lysine specific demethylase 6a 0.0032 0.008 0.008
Brugia malayi ERG2 and Sigma1 receptor like protein 0.0719 0.3953 0.3956
Brugia malayi hypothetical protein 0.0128 0.0621 0.0621
Brugia malayi beta-lactamase 0.0039 0.0119 0.0119
Leishmania major 4-coumarate:coa ligase-like protein 0.0025 0.0037 0.0037
Trypanosoma cruzi ferric reductase transmembrane protein, putative 0.0033 0.0084 0.0084
Onchocerca volvulus 0.0147 0.0724 0.5582
Treponema pallidum ribonuclease H (rnhA) 0.0027 0.0047 0.0048
Giardia lamblia Hypothetical protein 0.0246 0.1286 0.1287
Loa Loa (eye worm) hypothetical protein 0.004 0.0123 0.0123
Brugia malayi Muscleblind-like protein 0.0145 0.0715 0.0716
Plasmodium falciparum JmjC domain-containing protein, putative 0.0032 0.008 0.008
Schistosoma mansoni sodium/chloride dependent transporter 0.004 0.0123 0.0123
Onchocerca volvulus 0.0025 0.0037 0.0176
Trypanosoma brucei FKBP-type peptidylprolyl cis-trans isomerase, putative 0.0246 0.1286 0.1287
Echinococcus granulosus sodium and chloride dependent glycine 0.004 0.0123 0.0123
Trypanosoma cruzi peptidyl-prolyl cis-trans isomerase, putative 0.0246 0.1286 0.1287
Schistosoma mansoni tar DNA-binding protein 0.0066 0.0271 0.0271
Echinococcus multilocularis Jumonji, AT rich interactive domain 1B 0.0032 0.008 0.008
Brugia malayi beta-lactamase family protein 0.0039 0.0119 0.0119
Onchocerca volvulus 0.0236 0.1229 0.9547
Echinococcus granulosus sodium and chloride dependent glycine 0.004 0.0123 0.0123
Trypanosoma cruzi DNA repair and recombination helicase protein PIF7, putative 0.0034 0.0087 0.0087
Echinococcus multilocularis JmjC domain containing protein 4 0.0032 0.008 0.008
Trypanosoma cruzi peptidyl-prolyl cis-trans isomerase, putative 0.1789 0.9992 1
Plasmodium vivax protein kinase Crk2 0.0045 0.0152 0.0152
Schistosoma mansoni thyroid hormone receptor 0.0021 0.0015 0.0015
Echinococcus multilocularis peptidyl prolyl cis trans isomerase FKBP4 0.1544 0.8611 0.8611
Brugia malayi jmjC domain containing protein 0.0032 0.008 0.008
Trypanosoma cruzi cdc2-related kinase 3 0.0045 0.0152 0.0152
Echinococcus multilocularis cyclin dependent kinase 1 0.0045 0.0152 0.0152
Loa Loa (eye worm) pigment dispersing factor receptor c 0.0048 0.017 0.017
Schistosoma mansoni nuclear hormone receptor 0.0021 0.0015 0.0015
Brugia malayi Sodium:neurotransmitter symporter family protein 0.004 0.0123 0.0123
Mycobacterium ulcerans hypothetical protein 0.0039 0.0119 0.0119
Loa Loa (eye worm) hypothetical protein 0.0032 0.008 0.008
Schistosoma mansoni hypothetical protein 0.004 0.012 0.012
Loa Loa (eye worm) nuclear Hormone Receptor family member 0.0021 0.0015 0.0015
Echinococcus granulosus FTZ F1 alpha 0.0021 0.0015 0.0015
Echinococcus granulosus Transcription factor JmjC domain containing protein 0.0121 0.0582 0.0582
Echinococcus granulosus Niemann Pick C1 protein 0.0096 0.0436 0.0436
Echinococcus granulosus uncharacterized sodium dependent transporter 0.004 0.0123 0.0123
Brugia malayi FKBP-type peptidyl-prolyl cis-trans isomerase-13, BmFKBP-13 0.0246 0.1286 0.1287
Mycobacterium leprae conserved hypothetical protein 0.0039 0.0119 0.0656
Echinococcus multilocularis jumonji domain containing 1A 0.0032 0.008 0.008
Schistosoma mansoni phosphoglucomutase 0.0027 0.0047 0.0047
Loa Loa (eye worm) hypothetical protein 0.0021 0.0015 0.0015
Echinococcus granulosus sodium dependent neurotransmitter transporter 0.004 0.0123 0.0123
Entamoeba histolytica peptidyl-prolyl cis-trans isomerase, FKBP-type , putative 0.179 1 1
Trichomonas vaginalis fk506-binding protein, putative 0.1789 0.9992 1
Plasmodium vivax 70 kDa peptidylprolyl isomerase, putative 0.1789 0.9992 1
Loa Loa (eye worm) TAR-binding protein 0.0066 0.0271 0.0272
Trypanosoma brucei cdc2-related kinase 1 0.0045 0.0152 0.0152
Echinococcus multilocularis cyclin dependent kinase 5 activator 1 0.0268 0.1409 0.1409
Echinococcus granulosus sterol regulatory element binding protein 0.0041 0.0128 0.0128
Loa Loa (eye worm) hypothetical protein 0.0019 0.0002 0.0002
Brugia malayi RNA recognition motif domain containing protein 0.0066 0.0271 0.0272
Schistosoma mansoni sodium-dependent neurotransmitter transporter 0.004 0.0123 0.0123
Onchocerca volvulus 0.0039 0.0119 0.0821
Brugia malayi FKBP-type peptidyl-prolyl cis-trans isomerase-33, BmFKBP-33 0.0246 0.1286 0.1287
Loa Loa (eye worm) hypothetical protein 0.0019 0.0002 0.0002
Loa Loa (eye worm) hypothetical protein 0.0236 0.1229 0.123
Toxoplasma gondii histone lysine demethylase JMJC1/KDM5D/JARID1D 0.0032 0.008 0.0619
Trypanosoma brucei PAB1-binding protein , putative 0.0024 0.0035 0.0035
Plasmodium falciparum peptidyl-prolyl cis-trans isomerase, putative 0.0246 0.1286 0.1287
Mycobacterium ulcerans lipase LipD 0.0039 0.0119 0.0119
Trypanosoma cruzi FK506-binding protein (FKBP)-type peptidyl-prolyl isomerase, putative 0.1789 0.9992 1
Echinococcus multilocularis protein dispatched 1 0.0047 0.0161 0.0161
Mycobacterium tuberculosis Conserved protein 0.0039 0.0119 0.0905
Mycobacterium ulcerans acyl-CoA synthetase 0.0025 0.0037 0.0037
Loa Loa (eye worm) hypothetical protein 0.0367 0.197 0.1972
Echinococcus multilocularis uncharacterized sodium dependent transporter 0.004 0.0123 0.0123
Schistosoma mansoni immunophilin 0.179 1 1
Echinococcus multilocularis sodium and chloride dependent glycine 0.004 0.0123 0.0123
Echinococcus multilocularis 0.0246 0.1286 0.1286
Toxoplasma gondii ABC1 family protein 0.0039 0.0119 0.0926
Trypanosoma brucei unspecified product 0.0029 0.006 0.006
Plasmodium vivax ataxin-2 like protein, putative 0.0024 0.0035 0.0035
Brugia malayi AMP-binding enzyme family protein 0.0025 0.0037 0.0037
Schistosoma mansoni fk506 binding protein 0.0246 0.1286 0.1286
Schistosoma mansoni hypothetical protein 0.004 0.012 0.012
Trypanosoma brucei retrotransposon hot spot protein 4 (RHS4), interrupted 0.0029 0.006 0.006
Schistosoma mansoni cyclin-dependent kinase 5 activator 0.0268 0.1409 0.1409
Giardia lamblia FKBP-type peptidyl-prolyl cis-trans isomerase 0.0246 0.1286 0.1287
Brugia malayi hypothetical protein 0.004 0.0123 0.0123
Trypanosoma brucei peptidyl-prolyl cis-trans isomerase, putative 0.0246 0.1286 0.1287
Schistosoma mansoni FTZ-F1 nuclear receptor-like protein 0.0021 0.0015 0.0015
Toxoplasma gondii Sodium:neurotransmitter symporter family protein 0.004 0.0123 0.0957
Leishmania major hypothetical protein, conserved 0.0039 0.0119 0.0119
Mycobacterium ulcerans long-chain fatty-acid CoA ligase 0.0025 0.0037 0.0037
Loa Loa (eye worm) hypothetical protein 0.0021 0.0015 0.0015
Entamoeba histolytica hypothetical protein, conserved 0.0034 0.0087 0.0087
Entamoeba histolytica peptidyl-prolyl cis-trans isomerase, putative 0.0246 0.1286 0.1286
Toxoplasma gondii histone lysine demethylase JMJD6a 0.0032 0.008 0.0619
Trypanosoma cruzi DNA repair and recombination helicase protein PIF7, putative 0.0034 0.0087 0.0087
Schistosoma mansoni phosphoglucomutase 0.0027 0.0047 0.0047
Loa Loa (eye worm) hypothetical protein 0.0128 0.0621 0.0621
Schistosoma mansoni immunophilin FK506 binding protein FKBP12 0.1789 0.9992 0.9992
Trypanosoma brucei DNA repair and recombination helicase protein PIF6 0.0034 0.0087 0.0087
Brugia malayi FKBP-type peptidyl-prolyl cis-trans isomerase-30, BmFKBP-30 0.0246 0.1286 0.1287
Loa Loa (eye worm) steroid hormone receptor 0.0021 0.0015 0.0015
Mycobacterium ulcerans fatty-acid-CoA ligase 0.0019 0.0002 0.0002
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0021 0.0015 0.0015
Schistosoma mansoni serine/threonine protein kinase 0.0045 0.0152 0.0152
Loa Loa (eye worm) hypothetical protein 0.005 0.018 0.0181
Loa Loa (eye worm) beta-LACTamase domain containing family member 0.0039 0.0119 0.0119
Echinococcus granulosus ribonuclease H1 0.0027 0.0047 0.0047
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0021 0.0015 0.0015
Schistosoma mansoni sodium-dependent neurotransmitter transporter 0.004 0.0123 0.0123
Entamoeba histolytica Niemann-Pick C1 protein, putative 0.0096 0.0436 0.0436
Trypanosoma brucei ribonuclease H1 0.0027 0.0047 0.0048
Toxoplasma gondii peptidyl-prolyl isomerase FKBP12, putative 0.0246 0.1286 1
Mycobacterium tuberculosis Fatty-acid-AMP ligase FadD30 (fatty-acid-AMP synthetase) (fatty-acid-AMP synthase) 0.0019 0.0002 0.0013
Trichomonas vaginalis CMGC family protein kinase 0.0045 0.0152 0.0152
Trypanosoma cruzi cdc2-related kinase 3 0.0045 0.0152 0.0152
Leishmania major hypothetical protein, conserved 0.0024 0.0035 0.0035
Onchocerca volvulus 0.004 0.0123 0.0852
Loa Loa (eye worm) hypothetical protein 0.0021 0.0015 0.0015
Schistosoma mansoni tar DNA-binding protein 0.0066 0.0271 0.0271
Mycobacterium ulcerans long-chain-fatty-acid-CoA ligase 0.0025 0.0037 0.0037
Loa Loa (eye worm) blistered cuticle protein 3 0.0033 0.0084 0.0084
Loa Loa (eye worm) norepinephrine transporter 0.0236 0.1229 0.123
Trypanosoma brucei hypothetical protein, conserved 0.0246 0.1286 0.1287
Loa Loa (eye worm) hypothetical protein 0.0019 0.0002 0.0002
Echinococcus granulosus retinoic acid receptor rxr beta a 0.0021 0.0015 0.0015
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0039 0.0119 0.0119
Trypanosoma cruzi macrophage infectivity potentiator, precursor, putative 0.0246 0.1286 0.1287
Plasmodium vivax acyl-CoA synthetase, putative 0.0019 0.0002 0.0002
Echinococcus multilocularis atpase aaa+ type core atpase aaa type core 0.0886 0.4899 0.4899
Loa Loa (eye worm) hypothetical protein 0.004 0.0123 0.0123
Loa Loa (eye worm) hypothetical protein 0.0025 0.0037 0.0037
Loa Loa (eye worm) hypothetical protein 0.004 0.0123 0.0123
Trypanosoma brucei C-8 sterol isomerase, putative 0.0719 0.3953 0.3956
Schistosoma mansoni hypothetical protein 0.01 0.0461 0.0461
Schistosoma mansoni protein phosphatase 2C 0.0032 0.008 0.008
Wolbachia endosymbiont of Brugia malayi FKBP-type peptidylprolyl isomerase 0.0246 0.1286 1
Echinococcus multilocularis expressed conserved protein 0.009 0.0403 0.0403
Loa Loa (eye worm) RNA recognition domain-containing protein domain-containing protein 0.0066 0.0271 0.0272
Echinococcus multilocularis beta LACTamase domain containing family member 0.0039 0.0119 0.0119
Trypanosoma brucei ferric reductase transmembrane protein, putative 0.0033 0.0084 0.0084
Echinococcus granulosus Protein patched homolog 1 0.0041 0.0128 0.0128
Giardia lamblia FKBP-type peptidyl-prolyl cis-trans isomerase 0.1789 0.9992 1
Trypanosoma cruzi FK506-binding protein (FKBP)-type peptidyl-prolyl isomerase, putative 0.1789 0.9992 1
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0021 0.0015 0.0015
Echinococcus multilocularis COUP TF:Svp nuclear hormone receptor 0.0021 0.0015 0.0015
Brugia malayi RNase H family protein 0.0027 0.0047 0.0048
Mycobacterium ulcerans beta-lactamase 0.0039 0.0119 0.0119
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0021 0.0015 0.0015
Wolbachia endosymbiont of Brugia malayi FKBP-type peptidylprolyl isomerase 0.0246 0.1286 1
Brugia malayi Nuclear hormone receptor family member nhr-14 0.0021 0.0015 0.0015
Loa Loa (eye worm) hypothetical protein 0.0019 0.0002 0.0002
Loa Loa (eye worm) FKBP-type peptidyl-prolyl cis-trans isomerase-13 0.0246 0.1286 0.1287
Mycobacterium ulcerans fatty-acid-CoA ligase 0.0025 0.0037 0.0037
Loa Loa (eye worm) hypothetical protein 0.0039 0.0119 0.0119
Echinococcus granulosus COUP TF:Svp nuclear hormone receptor 0.0021 0.0015 0.0015
Onchocerca volvulus Ribonuclease H1 homolog 0.0027 0.0047 0.0258
Brugia malayi Corticotropin releasing factor receptor 2 precursor, putative 0.0048 0.017 0.017
Echinococcus multilocularis sterol regulatory element binding protein 0.0041 0.0128 0.0128
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0021 0.0015 0.0015
Schistosoma mansoni sodium/chloride dependent transporter 0.0236 0.1229 0.1229
Treponema pallidum peptidyl-prolyl cis-trans isomerase, FKBP-type, 22 kDa (fklB) 0.1789 0.9992 1
Echinococcus granulosus cyclin dependent kinase 5 0.0045 0.0152 0.0152
Brugia malayi hypothetical protein 0.0119 0.0568 0.0568
Schistosoma mansoni jumonji domain containing protein 0.0032 0.008 0.008
Brugia malayi Nuclear hormone receptor family member nhr-31 0.0021 0.0015 0.0015
Brugia malayi Niemann-Pick C1 protein precursor 0.0096 0.0436 0.0436
Schistosoma mansoni sodium/chloride dependent neurotransmitter transporter 0.004 0.0123 0.0123
Trypanosoma brucei hypothetical protein, conserved 0.0029 0.006 0.006
Trypanosoma cruzi JmjC domain, hydroxylase, putative 0.0032 0.008 0.008
Brugia malayi Sodium:neurotransmitter symporter family protein 1, putative 0.004 0.0123 0.0123
Echinococcus multilocularis muscleblind protein 0.0145 0.0715 0.0715
Mycobacterium tuberculosis Possible penicillin-binding protein 0.0251 0.1316 1
Schistosoma mansoni sodium/chloride dependent transporter 0.0041 0.0126 0.0126
Loa Loa (eye worm) hypothetical protein 0.0021 0.0015 0.0015
Onchocerca volvulus 0.0246 0.1286 1
Loa Loa (eye worm) hypothetical protein 0.004 0.0123 0.0123
Echinococcus granulosus phd:f box containing protein 0.0032 0.008 0.008
Trypanosoma brucei peptidyl-prolyl cis-trans isomerase, putative 0.1789 0.9992 1
Mycobacterium ulcerans esterase/lipase LipP 0.0039 0.0119 0.0119
Trypanosoma brucei JmjC domain, hydroxylase, putative 0.0032 0.008 0.008
Echinococcus granulosus JmjC domain containing protein 4 0.0032 0.008 0.008
Brugia malayi Calcitonin receptor-like protein seb-1 0.0048 0.017 0.017
Echinococcus granulosus cyclin dependent kinase 0.0045 0.0152 0.0152
Loa Loa (eye worm) FKBP-type peptidyl-prolyl cis-trans isomerase-30 0.0246 0.1286 0.1287
Leishmania major peptidylprolyl isomerase-like protein 0.1789 0.9992 1
Toxoplasma gondii ribonuclease HI protein 0.0027 0.0047 0.0369
Trichomonas vaginalis conserved hypothetical protein 0.0246 0.1286 0.1287
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD2 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0025 0.0037 0.0282
Loa Loa (eye worm) hypothetical protein 0.0041 0.0128 0.0128
Mycobacterium ulcerans acyl-CoA synthetase 0.0025 0.0037 0.0037
Echinococcus granulosus tar DNA binding protein 0.0066 0.0271 0.0271
Echinococcus granulosus ecdysone induced protein 78C 0.0021 0.0015 0.0015
Toxoplasma gondii peptidyl-prolyl cis-trans isomerase, FKBP-type domain-containing protein 0.0246 0.1286 1
Onchocerca volvulus Dual oxidase homolog 0.0033 0.0084 0.0547
Schistosoma mansoni norepinephrine/norepinephrine transporter 0.004 0.0123 0.0123
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0021 0.0015 0.0015
Loa Loa (eye worm) hypothetical protein 0.1543 0.8603 0.861
Trichomonas vaginalis CMGC family protein kinase 0.0045 0.0152 0.0152
Echinococcus multilocularis muscleblind protein 1 0.0145 0.0715 0.0715
Schistosoma mansoni nuclear receptor 2DBD-gamma 0.0021 0.0015 0.0015
Plasmodium falciparum protein kinase 5 0.0045 0.0152 0.0152
Brugia malayi Nuclear hormone receptor family member nhr-1 0.0021 0.0015 0.0015
Brugia malayi steroid hormone receptor 0.0021 0.0015 0.0015
Plasmodium falciparum peptidyl-prolyl cis-trans isomerase FKBP35 0.1789 0.9992 1
Echinococcus multilocularis cyclin dependent kinase 5 0.0045 0.0152 0.0152
Giardia lamblia Ribonuclease H 0.0027 0.0047 0.0048
Echinococcus multilocularis sodium:chloride dependent neurotransmitter 0.004 0.0123 0.0123
Loa Loa (eye worm) hypothetical protein 0.0019 0.0002 0.0002
Trypanosoma brucei hypothetical protein, conserved 0.0039 0.0119 0.0119
Loa Loa (eye worm) hypothetical protein 0.004 0.0123 0.0123
Schistosoma mansoni sodium/chloride dependent neurotransmitter transporter 0.004 0.0123 0.0123
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0039 0.0119 0.0119
Trichomonas vaginalis fk506 binding protein, putative 0.0246 0.1286 0.1287
Loa Loa (eye worm) jmjC domain-containing protein 0.0032 0.008 0.008
Schistosoma mansoni phosphoglucomutase 0.0027 0.0047 0.0047
Trypanosoma cruzi FKBP-type peptidylprolyl cis-trans isomerase, putative 0.0246 0.1286 0.1287
Plasmodium falciparum acyl-CoA synthetase 0.0019 0.0002 0.0002
Schistosoma mansoni jumonji domain containing protein 0.0121 0.0582 0.0582
Echinococcus granulosus FTZ F1 nuclear receptor protein 0.0021 0.0015 0.0015
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0021 0.0015 0.0015
Trichomonas vaginalis CMGC family protein kinase 0.0045 0.0152 0.0152
Brugia malayi beta-lactamase family protein 0.0039 0.0119 0.0119
Loa Loa (eye worm) hypothetical protein 0.0236 0.1229 0.123
Loa Loa (eye worm) hypothetical protein 0.0021 0.0015 0.0015
Schistosoma mansoni hypothetical protein 0.004 0.012 0.012
Brugia malayi Hypothetical 52.5 kDa protein ZK945.1 in chromosome II, putative 0.0039 0.0119 0.0119
Brugia malayi Blistered cuticle protein 3 0.0033 0.0084 0.0084
Onchocerca volvulus 0.004 0.0123 0.0852
Toxoplasma gondii Sodium:neurotransmitter symporter family protein 0.004 0.0123 0.0957
Loa Loa (eye worm) hypothetical protein 0.0025 0.0037 0.0037
Echinococcus multilocularis ribonuclease H1 0.0027 0.0047 0.0047
Echinococcus multilocularis Nuclear hormone receptor family member nhr 41 0.0021 0.0015 0.0015
Brugia malayi Steroid receptor seven-up type 2 0.0021 0.0015 0.0015
Loa Loa (eye worm) beta-lactamase 0.0039 0.0119 0.0119
Trichomonas vaginalis immunophilin, putative 0.1789 0.9992 1
Toxoplasma gondii cell-cycle-associated protein kinase CDK, putative 0.0045 0.0152 0.1181
Echinococcus granulosus muscleblind protein 0.0145 0.0715 0.0715
Echinococcus granulosus Nuclear hormone receptor family member nhr 41 0.0021 0.0015 0.0015
Brugia malayi Sodium:neurotransmitter symporter family protein 0.0236 0.1229 0.123
Schistosoma mansoni immunophilin 0.1544 0.8611 0.8611
Echinococcus multilocularis lysine specific demethylase 5A 0.0121 0.0582 0.0582
Loa Loa (eye worm) hypothetical protein 0.0021 0.0015 0.0015
Schistosoma mansoni photoreceptor-specific nuclear receptor related 0.0021 0.0015 0.0015
Loa Loa (eye worm) FKBP5 protein 0.1789 0.9992 1
Echinococcus multilocularis ATP dependent DNA helicase PIF1 0.0034 0.0087 0.0087
Plasmodium falciparum transporter, putative 0.004 0.0123 0.0123
Schistosoma mansoni sodium/chloride dependent neurotransmitter transporter 0.004 0.0123 0.0123
Schistosoma mansoni hypothetical protein 0.0034 0.0087 0.0087
Brugia malayi cell division control protein 2 homolog 0.0045 0.0152 0.0152
Entamoeba histolytica peptidyl-prolyl cis-trans isomerase, FKBP-type, putative 0.179 1 1
Chlamydia trachomatis Ssodium-dependent amino acid transporter 0.004 0.0123 0.0945
Loa Loa (eye worm) hypothetical protein 0.0145 0.0715 0.0716
Leishmania major 4-coumarate:coa ligase-like protein 0.0025 0.0037 0.0037
Schistosoma mansoni phd/f-box containing protein 0.0032 0.008 0.008
Echinococcus multilocularis ecdysone induced protein 78C 0.0021 0.0015 0.0015
Onchocerca volvulus Huntingtin homolog 0.0119 0.0568 0.435
Trichomonas vaginalis D-aminoacylase, putative 0.0039 0.0119 0.0119
Brugia malayi ecdysteroid receptor 0.0021 0.0015 0.0015
Plasmodium falciparum amino acid transporter, putative 0.004 0.0123 0.0123
Mycobacterium tuberculosis Probable conserved lipoprotein 0.0039 0.0119 0.0905
Echinococcus multilocularis serotonin transporter 0.0236 0.1229 0.1229
Echinococcus granulosus cyclin dependent kinase 1 0.0045 0.0152 0.0152
Schistosoma mansoni jumonji/arid domain-containing protein 0.0121 0.0582 0.0582
Mycobacterium tuberculosis Conserved protein 0.0039 0.0119 0.0905
Schistosoma mansoni Tr4/Tr2 (homologue) 0.0021 0.0015 0.0015
Leishmania major FKBP-type peptidyl-prolyl cis-trans isomerase, putative 0.0246 0.1286 0.1287
Brugia malayi FKBP-type peptidyl-prolyl cis-trans isomerase-59, BmFKBP59 0.1789 0.9992 1
Echinococcus granulosus uncharacterized sodium dependent transporter 0.004 0.0123 0.0123
Trypanosoma brucei RNA helicase, putative 0.01 0.0461 0.0462
Brugia malayi Protein kinase domain containing protein 0.0045 0.0152 0.0152
Trypanosoma cruzi peptidyl-prolyl cis-trans isomerase, putative 0.0246 0.1286 0.1287
Leishmania major cell division protein kinase 2,cdc2-related kinase 0.0045 0.0152 0.0152
Trypanosoma cruzi DNA repair and recombination helicase protein PIF6, putative 0.0034 0.0087 0.0087
Loa Loa (eye worm) FKBP-type peptidyl-prolyl cis-trans isomerase-12 0.1789 0.9992 1
Loa Loa (eye worm) hypothetical protein 0.0045 0.0149 0.0149
Wolbachia endosymbiont of Brugia malayi ribonuclease HI 0.0027 0.0047 0.0369
Mycobacterium tuberculosis Conserved protein 0.0039 0.0119 0.0905
Echinococcus multilocularis tar DNA binding protein 0.0066 0.0271 0.0271
Trypanosoma brucei cdc2-related kinase 3 0.0045 0.0152 0.0152
Leishmania major peptidyl-prolyl cis-trans isomerase, putative 0.0246 0.1286 0.1287
Trypanosoma brucei FK506-binding protein (FKBP)-type peptidyl-prolyl isomerase, putative 0.1789 0.9992 1
Brugia malayi Nuclear hormone receptor family member nhr-41 0.0021 0.0015 0.0015
Mycobacterium ulcerans FK-506 binding protein, peptidyl-prolyl cis-trans isomerase 0.1789 0.9992 1
Loa Loa (eye worm) RNA binding protein 0.0066 0.0271 0.0272
Echinococcus granulosus sodium:chloride dependent neurotransmitter 0.004 0.0123 0.0123
Trichomonas vaginalis peptidylprolyl isomerase, putative 0.1789 0.9992 1
Brugia malayi nuclear hormone receptor 0.0021 0.0015 0.0015
Toxoplasma gondii LsmAD domain-containing protein 0.0024 0.0035 0.0272
Brugia malayi Nuclear hormone receptor family member nhr-40 0.0021 0.0015 0.0015
Mycobacterium ulcerans acyl-CoA synthetase 0.0025 0.0037 0.0037
Brugia malayi TAR-binding protein 0.0066 0.0271 0.0272
Echinococcus granulosus expressed conserved protein 0.009 0.0403 0.0403
Loa Loa (eye worm) nuclear hormone receptor family member nhr-49 0.0021 0.0015 0.0015
Onchocerca volvulus 0.004 0.0123 0.0852
Schistosoma mansoni thyroid hormone receptor 0.0021 0.0015 0.0015
Loa Loa (eye worm) nuclear hormone receptor family member nhr-14 0.0021 0.0015 0.0015
Mycobacterium tuberculosis Probable lipase LipE 0.0039 0.0119 0.0905
Echinococcus multilocularis FTZ F1 alpha 0.0021 0.0015 0.0015
Mycobacterium leprae PROBABLE TRIGGER FACTOR (TF) PROTEIN TIG 0.0246 0.1286 1
Brugia malayi hypothetical protein 0.0147 0.0724 0.0725
Treponema pallidum peptidyl-prolyl cis-trans isomerase, FKBP-type (slyD) 0.0246 0.1286 0.1287
Entamoeba histolytica DNA repair and recombination protein, putative 0.0034 0.0087 0.0087
Brugia malayi jmjC domain containing protein 0.0032 0.008 0.008
Loa Loa (eye worm) hypothetical protein 0.0039 0.0119 0.0119
Echinococcus multilocularis fk506 binding protein 0.1789 0.9992 0.9992
Loa Loa (eye worm) jmjC domain-containing protein 0.0121 0.0582 0.0582
Echinococcus granulosus Niemann Pick C1 protein 0.0137 0.0667 0.0667
Trichomonas vaginalis esterase, putative 0.0039 0.0119 0.0119
Echinococcus granulosus lysine specific demethylase 5A 0.0121 0.0582 0.0582
Trichomonas vaginalis fk506-binding protein, putative 0.0246 0.1286 0.1287
Trichomonas vaginalis penicillin-binding protein, putative 0.0039 0.0119 0.0119
Trypanosoma cruzi FKBP-type peptidylprolyl cis-trans isomerase, putative 0.0246 0.1286 0.1287
Plasmodium vivax peptidyl-prolyl cis-trans isomerase, putative 0.0246 0.1286 0.1287
Echinococcus granulosus FK506 binding protein 2 0.0246 0.1286 0.1286
Brugia malayi latrophilin 2 splice variant baaae 0.0033 0.0084 0.0084
Loa Loa (eye worm) hypothetical protein 0.0039 0.0119 0.0119
Trypanosoma cruzi JmjC domain, hydroxylase, putative 0.0032 0.008 0.008
Loa Loa (eye worm) hypothetical protein 0.0719 0.3953 0.3956
Brugia malayi jmjC domain containing protein 0.0121 0.0582 0.0582
Echinococcus granulosus peptidyl prolyl cis trans isomerase FKBP4 0.1544 0.8611 0.8611
Loa Loa (eye worm) hypothetical protein 0.0236 0.1229 0.123
Plasmodium vivax amine transporter, putative 0.004 0.0123 0.0123
Brugia malayi AMP-binding enzyme family protein 0.0025 0.0037 0.0037
Loa Loa (eye worm) Sodium:neurotransmitter symporter family protein 0.004 0.0123 0.0123
Loa Loa (eye worm) CMGC/CDK/CDC2 protein kinase 0.0045 0.0152 0.0152
Schistosoma mansoni hypothetical protein 0.0246 0.1286 0.1286
Brugia malayi nuclear receptor NHR-88 0.0021 0.0015 0.0015
Echinococcus multilocularis cyclin dependent kinase 1 0.0045 0.0152 0.0152
Echinococcus multilocularis FTZ F1 nuclear receptor protein 0.0021 0.0015 0.0015
Schistosoma mansoni phosphatidylserine receptor 0.0032 0.008 0.008
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0021 0.0015 0.0015
Echinococcus granulosus ATP dependent DNA helicase PIF1 0.0034 0.0087 0.0087
Loa Loa (eye worm) CMGC/CDK/CDC2 protein kinase 0.0045 0.0152 0.0152
Schistosoma mansoni jumonji/arid domain-containing protein 0.0121 0.0582 0.0582
Schistosoma mansoni immunophilin 0.179 1 1
Schistosoma mansoni steroid hormone receptor ad4bp 0.0021 0.0015 0.0015
Entamoeba histolytica acyl-CoA synthetase, putative 0.0025 0.0037 0.0037
Echinococcus granulosus FK506 binding protein 8 38 kDa 0.0246 0.1286 0.1286
Echinococcus granulosus hepatocyte nuclear factor 4 alpha 0.0021 0.0015 0.0015
Echinococcus multilocularis cyclin dependent kinase 0.0045 0.0152 0.0152
Loa Loa (eye worm) hypothetical protein 0.0048 0.017 0.017
Mycobacterium tuberculosis Probable hydrolase 0.0039 0.0119 0.0905
Trypanosoma cruzi ribonuclease H1, putative 0.0027 0.0047 0.0048
Echinococcus granulosus 5'partial|cyclin dependent kinase 1 0.0045 0.0152 0.0152
Giardia lamblia Kinase, CMGC CDK 0.0045 0.0152 0.0152

Activities

Activity type Activity value Assay description Source Reference
MIC (functional) = 6.25 ug ml-1 Antibacterial activity of the compound against S. aureus 209P JC-1 ChEMBL. 14643333
MIC (functional) = 6.25 ug ml-1 Antibacterial activity of the compound against methyllin resistant S. aureus M133 (MRSA) ChEMBL. 14643333
MIC (functional) = 6.25 ug ml-1 Antibacterial activity of the compound against methyllin resistant S. aureus M126 (MRSA) ChEMBL. 14643333
MIC (functional) = 6.25 ug ml-1 Antibacterial activity of the compound against S. epidermidis ATCC 14990 ChEMBL. 14643333
MIC (functional) = 6.25 ug ml-1 Antibacterial activity of the compound against E. hirae ATCC 8043 ChEMBL. 14643333
MIC (functional) = 6.25 ug ml-1 Antibacterial activity of the compound against E. faecalis W-73 ChEMBL. 14643333
MIC (functional) = 6.25 ug ml-1 Antibacterial activity of the compound against vancomycin resistant E. faecalis NCTC 12201 (VRE) ChEMBL. 14643333
MIC (functional) = 12.5 ug ml-1 Antibacterial activity of the compound against vancomycin resistant E. faecium vanA (VRE) ChEMBL. 14643333

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
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External resources for this compound

Bibliographic References

1 literature reference was collected for this gene.

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