Detailed information for compound 40388

Basic information

Technical information
  • TDR Targets ID: 40388
  • Name: 1-(2-aminoethyl)-3-(2,6-dibromophenyl)thioure a
  • MW: 353.077 | Formula: C9H11Br2N3S
  • H donors: 2 H acceptors: 0 LogP: 2.24 Rotable bonds: 4
    Rule of 5 violations (Lipinski): 1
  • SMILES: NCC/N=C(/Nc1c(Br)cccc1Br)\S
  • InChi: 1S/C9H11Br2N3S/c10-6-2-1-3-7(11)8(6)14-9(15)13-5-4-12/h1-3H,4-5,12H2,(H2,13,14,15)
  • InChiKey: WXEUOYNJQUDBSF-UHFFFAOYSA-N  


Substructure search Similarity search

Network

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Synonyms

  • 1-(2-azanylethyl)-3-(2,6-dibromophenyl)thiourea

Targets

Known targets for this compound

No curated genes were found associated with this compound

Predicted pathogen targets for this compound

By orthology
No druggable targets predicted by orthology data
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Echinococcus granulosus Cys loop ligand gated ion channel subunit 0.0018 0.0006 0.0016
Trypanosoma cruzi aldehyde dehydrogenase, putative 0.0027 0.0039 0.0037
Mycobacterium tuberculosis Probable NADPH:adrenodoxin oxidoreductase FprB (adrenodoxin reductase) (AR) (ferredoxin-NADP(+) reductase) 0.0039 0.0085 0.0201
Mycobacterium ulcerans dihydrolipoamide dehydrogenase 0.0148 0.0493 0.2761
Schistosoma mansoni opsin-like receptor 0.0034 0.0067 0.0132
Schistosoma mansoni myosin xvIII 0.0034 0.0067 0.0132
Loa Loa (eye worm) hypothetical protein 0.0034 0.0067 0.0062
Brugia malayi Nuclear hormone receptor-like 1 0.1012 0.3746 0.3746
Echinococcus multilocularis nuclear receptor nhr 48 0.0048 0.0117 0.0452
Loa Loa (eye worm) hypothetical protein 0.0038 0.0082 0.0077
Mycobacterium ulcerans flavoprotein disulfide reductase 0.0148 0.0493 0.2761
Trichomonas vaginalis CAMK family protein kinase 0.0471 0.1711 0.6635
Echinococcus multilocularis regulator of G protein signaling 3 0.0019 0.0009 0.003
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0109 0.0347 0.0687
Loa Loa (eye worm) hypothetical protein 0.0038 0.0082 0.0077
Loa Loa (eye worm) hypothetical protein 0.1006 0.3725 0.3722
Schistosoma mansoni norepinephrine/norepinephrine transporter 0.0475 0.1726 0.3419
Mycobacterium tuberculosis Probable oxidoreductase 0.108 0.4 1
Trichomonas vaginalis CAMK family protein kinase 0.0471 0.1711 0.6635
Schistosoma mansoni peptide (FMRFamide/neurokinin-3)-like receptor 0.0034 0.0067 0.0132
Echinococcus multilocularis histone lysine methyltransferase setb histone lysine methyltransferase eggless 0.0109 0.0347 0.1349
Onchocerca volvulus Putative hydroxypyruvate isomerase 0.002 0.0011 0.0043
Loa Loa (eye worm) hypothetical protein 0.0018 0.0006 0.0001
Loa Loa (eye worm) hypothetical protein 0.0034 0.0067 0.0062
Echinococcus multilocularis expressed protein 0.037 0.1328 0.5184
Loa Loa (eye worm) hypothetical protein 0.0048 0.0117 0.0113
Echinococcus multilocularis dihydrolipoamide dehydrogenase 0.0148 0.0493 0.192
Schistosoma mansoni FTZ-F1 nuclear receptor-like protein 0.0101 0.0318 0.063
Schistosoma mansoni nuclear hormone receptor 0.0048 0.0117 0.0232
Echinococcus granulosus apoptosis inducing factor 1 mitochondrial 0.0039 0.0085 0.0311
Onchocerca volvulus 0.0018 0.0006 0.0022
Trypanosoma brucei polo-like protein kinase 0.0471 0.1711 0.171
Echinococcus multilocularis glycine receptor subunit alpha 1 0.0039 0.0085 0.0328
Trypanosoma brucei dihydrolipoamide dehydrogenase 0.0148 0.0493 0.0492
Echinococcus granulosus pyroglutamylated rfamide peptide receptor 0.0034 0.0067 0.0243
Echinococcus multilocularis neuropeptides capa receptor 0.0034 0.0067 0.0255
Mycobacterium ulcerans NAD-dependent aldehyde dehydrogenase AldA 0.0027 0.0039 0.0192
Loa Loa (eye worm) hypothetical protein 0.0021 0.0017 0.0012
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0033 0.0061 0.0233
Leishmania major cathepsin L-like protease 0.0125 0.0409 0.0404
Schistosoma mansoni intermediate filament proteins 0.0082 0.0248 0.0491
Leishmania major NADH dehydrogenase, putative 0.0039 0.0085 0.008
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0125 0.0409 0.0408
Schistosoma mansoni Cys-loop ligand gated ion channel subunit 0.0021 0.0017 0.0034
Trypanosoma brucei pyridine nucleotide-disulphide oxidoreductase, putative 0.0039 0.0085 0.0084
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0125 0.0409 0.0408
Schistosoma mansoni succinate semialdehyde dehydrogenase 0.0027 0.0039 0.0076
Mycobacterium tuberculosis Possible dehydrogenase/reductase 0.0039 0.0085 0.0201
Plasmodium falciparum type II NADH:ubiquinone oxidoreductase 0.0039 0.0085 0.0544
Loa Loa (eye worm) pre-SET domain-containing protein family protein 0.0617 0.2259 0.2255
Leishmania major cathepsin L-like protease 0.0125 0.0409 0.0404
Toxoplasma gondii pyridine nucleotide-disulfide oxidoreductase domain-containing protein 0.0039 0.0085 0.0454
Loa Loa (eye worm) hypothetical protein 0.0039 0.0085 0.0081
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0044 0.0102 0.0393
Schistosoma mansoni hypothetical protein 0.05 0.1819 0.3604
Echinococcus granulosus cathepsin L cysteine proteinase 0.0033 0.0061 0.0223
Onchocerca volvulus 0.0033 0.0061 0.0237
Plasmodium falciparum cysteine proteinase falcipain 2b 0.0033 0.0061 0.039
Onchocerca volvulus 0.0034 0.0067 0.0258
Loa Loa (eye worm) hypothetical protein 0.0048 0.0117 0.0113
Loa Loa (eye worm) hypothetical protein 0.0039 0.0085 0.0081
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0148 0.0493 0.0492
Entamoeba histolytica hypothetical protein 0.0021 0.0017 0.0092
Loa Loa (eye worm) 3-hydroxyacyl-CoA dehydrogenase type II 0.0053 0.0137 0.0132
Trichomonas vaginalis CAMK family protein kinase 0.0471 0.1711 0.6635
Loa Loa (eye worm) G protein signaling regulator EGL-10 0.0019 0.0009 0.0004
Schistosoma mansoni cpg binding protein 0.0155 0.052 0.103
Trichomonas vaginalis disulfide oxidoreductase, putative 0.0039 0.0085 0.0325
Loa Loa (eye worm) hypothetical protein 0.0286 0.1013 0.1009
Loa Loa (eye worm) hypothetical protein 0.0039 0.0085 0.0081
Brugia malayi Bloom's syndrome protein homolog 0.0021 0.0015 0.0015
Echinococcus granulosus lamin dm0 0.0082 0.0248 0.0917
Echinococcus multilocularis g protein coupled receptor 0.0034 0.0067 0.0255
Loa Loa (eye worm) hypothetical protein 0.0034 0.0067 0.0062
Loa Loa (eye worm) hypothetical protein 0.0081 0.0241 0.0237
Echinococcus granulosus g protein linked acetylcholine receptor gar 2a 0.0034 0.0067 0.0243
Onchocerca volvulus 0.0039 0.0085 0.033
Brugia malayi hypothetical protein 0.0081 0.0241 0.0241
Echinococcus granulosus lamin 0.0082 0.0248 0.0917
Onchocerca volvulus 0.0039 0.0085 0.033
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0148 0.0493 0.0492
Brugia malayi ecdysone receptor 0.0048 0.0117 0.0117
Plasmodium vivax NAD(P)H-dependent glutamate synthase, putative 0.0039 0.0085 0.0544
Loa Loa (eye worm) hypothetical protein 0.0101 0.0318 0.0314
Brugia malayi Nuclear hormone receptor family member nhr-3 0.0101 0.0318 0.0318
Trypanosoma brucei C-8 sterol isomerase, putative 0.2674 1 1
Brugia malayi hypothetical protein 0.0034 0.0067 0.0067
Brugia malayi Papain family cysteine protease containing protein 0.0033 0.0061 0.0061
Toxoplasma gondii Sodium:neurotransmitter symporter family protein 0.0081 0.0241 0.1338
Loa Loa (eye worm) steroid hormone receptor 0.0101 0.0318 0.0314
Echinococcus multilocularis rhodopsin orphan GPCR 0.0034 0.0067 0.0255
Schistosoma mansoni Cys-loop ligand gated ion channel subunit 0.0039 0.0085 0.0169
Echinococcus granulosus beta-adrenergic receptor kinase 0.0021 0.0015 0.005
Trichomonas vaginalis disulfide oxidoreductase, putative 0.0039 0.0085 0.0325
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0033 0.0061 0.0233
Trichomonas vaginalis apoptosis inducing factor, putative 0.0039 0.0085 0.0325
Loa Loa (eye worm) hypothetical protein 0.0098 0.0308 0.0304
Mycobacterium ulcerans aldehyde dehydrogenase (NAD+) dependent 0.0027 0.0039 0.0192
Brugia malayi Papain family cysteine protease containing protein 0.0017 0.0001 0.0001
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0101 0.0318 0.0318
Echinococcus multilocularis methyl CpG binding domain protein 2 0.0018 0.0004 0.0009
Brugia malayi intermediate filament protein 0.0082 0.0248 0.0248
Echinococcus granulosus gamma aminobutyric acid receptor subunit 0.0018 0.0006 0.0016
Brugia malayi Sodium:neurotransmitter symporter family protein 0.0475 0.1726 0.1726
Trichomonas vaginalis conserved hypothetical protein 0.0019 0.0009 0.003
Brugia malayi Cathepsin L-like precursor 0.0022 0.002 0.002
Loa Loa (eye worm) hypothetical protein 0.0018 0.0006 0.0001
Echinococcus multilocularis bromodomain adjacent to zinc finger domain 0.007 0.02 0.0775
Loa Loa (eye worm) hypothetical protein 0.0039 0.0085 0.0081
Trichomonas vaginalis dihydroorotate dehydrogenase, putative 0.0039 0.0085 0.0325
Trypanosoma cruzi dihydrolipoyl dehydrogenase, putative 0.0148 0.0493 0.0492
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0033 0.0061 0.0233
Mycobacterium tuberculosis Probable NADH dehydrogenase Ndh 0.0971 0.3593 0.8979
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0044 0.0102 0.0393
Entamoeba histolytica aldehyde-alcohol dehydrogenase 2, putative 0.0027 0.0039 0.0218
Echinococcus multilocularis rhodopsin orphan GPCR 0.0034 0.0067 0.0255
Toxoplasma gondii histone lysine methyltransferase SET/SUV39 0.0091 0.0281 0.1562
Echinococcus multilocularis dihydropyrimidine dehydrogenase (NADP+) 0.0039 0.0085 0.0327
Loa Loa (eye worm) hypothetical protein 0.0081 0.0241 0.0237
Echinococcus multilocularis sulfide:quinone oxidoreductase 0.0039 0.0085 0.0327
Brugia malayi Aldehyde dehydrogenase protein 4 0.0027 0.0039 0.0039
Echinococcus multilocularis 7TM GPCR, rhodopsin 0.0034 0.0067 0.0255
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0044 0.0102 0.0393
Echinococcus multilocularis g protein linked acetylcholine receptor gar 2a 0.0034 0.0067 0.0255
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0033 0.0061 0.0233
Echinococcus multilocularis arachidonate 5 lipoxygenase 0.0171 0.0583 0.2271
Mycobacterium ulcerans succinate-semialdehyde dehydrogenase 0.0027 0.0039 0.0192
Brugia malayi Papain family cysteine protease containing protein 0.0017 0.0001 0.0001
Trypanosoma cruzi aldehyde dehydrogenase, putative 0.0027 0.0039 0.0037
Echinococcus granulosus g protein coupled receptor 0.0034 0.0067 0.0243
Trichomonas vaginalis dihydropyrimidine dehydrogenase, putative 0.0039 0.0085 0.0325
Echinococcus multilocularis regulator of G protein signaling 7 0.0019 0.0009 0.003
Schistosoma mansoni nAChR subunit 0.0039 0.0085 0.0169
Echinococcus granulosus rhodopsin orphan GPCR 0.0034 0.0067 0.0243
Brugia malayi Nuclear hormone receptor family member nhr-1 0.0101 0.0318 0.0318
Schistosoma mansoni serine/threonine protein kinase 0.0021 0.0015 0.0029
Schistosoma mansoni thyrotropin-releasing hormone receptor 0.0034 0.0067 0.0132
Echinococcus granulosus dihydropyrimidine dehydrogenase NADP 0.0039 0.0085 0.0311
Loa Loa (eye worm) hypothetical protein 0.0053 0.0139 0.0134
Brugia malayi Pyridine nucleotide-disulphide oxidoreductase family protein 0.0039 0.0085 0.0085
Schistosoma mansoni acetylcholine receptor subunit beta 0.0018 0.0006 0.0011
Toxoplasma gondii pyridine nucleotide-disulfide oxidoreductase domain-containing protein 0.0039 0.0085 0.0454
Trypanosoma cruzi cysteine peptidase, putative 0.0125 0.0409 0.0408
Trypanosoma brucei delta-1-pyrroline-5-carboxylate dehydrogenase, putative 0.0027 0.0039 0.0037
Loa Loa (eye worm) hypothetical protein 0.0034 0.0067 0.0062
Echinococcus multilocularis COUP TF:Svp nuclear hormone receptor 0.0101 0.0318 0.1238
Echinococcus granulosus g protein coupled receptor 0.0034 0.0067 0.0243
Brugia malayi ORL1-like opioid receptor 0.0034 0.0067 0.0067
Trypanosoma brucei trypanothione reductase 0.0426 0.154 0.1539
Schistosoma mansoni hypothetical protein 0.0034 0.0067 0.0132
Schistosoma mansoni aldehyde dehydrogenase 0.0488 0.1773 0.3512
Trypanosoma cruzi polo-like protein kinase, putative 0.0471 0.1711 0.171
Brugia malayi hypothetical protein 0.0018 0.0006 0.0006
Onchocerca volvulus Steroid hormone receptor family member cnr14 homolog 0.0101 0.0318 0.1234
Brugia malayi hypothetical protein 0.0048 0.0117 0.0117
Giardia lamblia Thioredoxin reductase 0.0039 0.0085 0.0277
Echinococcus granulosus Nuclear hormone receptor family member nhr 41 0.0101 0.0318 0.1178
Toxoplasma gondii thioredoxin reductase 0.0426 0.154 0.8683
Plasmodium falciparum transporter, putative 0.0081 0.0241 0.1559
Brugia malayi Nuclear hormone receptor family member nhr-49 0.0101 0.0318 0.0318
Brugia malayi Dopamine receptor protein 1 0.0034 0.0067 0.0067
Trichomonas vaginalis disulfide oxidoreductase, putative 0.0039 0.0085 0.0325
Brugia malayi hypothetical protein 0.0018 0.0006 0.0006
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0033 0.0061 0.0233
Chlamydia trachomatis endonuclease IV 0.0074 0.0218 0.412
Schistosoma mansoni sodium-dependent amino acid transporter 0.0081 0.0241 0.0478
Onchocerca volvulus 0.0034 0.0067 0.0258
Trichomonas vaginalis conserved hypothetical protein 0.0019 0.0009 0.003
Plasmodium vivax hypothetical protein, conserved 0.0081 0.0241 0.1559
Mycobacterium leprae PROBABLE GAMMA-GLUTAMYL PHOSPHATE REDUCTASE PROTEIN PROA (GPR) (GLUTAMATE-5-SEMIALDEHYDE DEHYDROGENASE) (GLUTAMYL-GAMMA-SEMIALDE 0.0027 0.0039 0.0085
Trypanosoma cruzi aldehyde dehydrogenase, putative 0.0027 0.0039 0.0037
Echinococcus granulosus lipoxygenase domain containing protein 0.0039 0.0084 0.0309
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0101 0.0318 0.1238
Brugia malayi Bromodomain containing protein 0.0039 0.0086 0.0086
Onchocerca volvulus Aldehyde dehydrogenase homolog 0.0027 0.0039 0.0149
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0033 0.0061 0.0233
Echinococcus multilocularis betaine aldehyde dehydrogenase 0.0027 0.0039 0.0146
Trichomonas vaginalis CAMK family protein kinase 0.0471 0.1711 0.6635
Echinococcus multilocularis 3 hydroxyacyl coenzyme A dehydrogenase type 2 0.0061 0.0165 0.0641
Loa Loa (eye worm) hypothetical protein 0.0039 0.0085 0.0081
Echinococcus granulosus Ankyrin repeat domain containing protein 0.0087 0.0266 0.0984
Trypanosoma cruzi NADPH:adrenodoxin oxidoreductase, mitochondrial, putative 0.0039 0.0085 0.0084
Schistosoma mansoni methyl-cpg binding protein mbd 0.0018 0.0004 0.0007
Schistosoma mansoni norepinephrine/norepinephrine transporter 0.0081 0.0241 0.0478
Echinococcus granulosus alpha 1A adrenergic receptor 0.0034 0.0067 0.0243
Giardia lamblia Glutamate synthase 0.0039 0.0085 0.0277
Brugia malayi Delta-1-pyrroline-5-carboxylate dehydrogenase, mitochondrial precursor 0.0027 0.0039 0.0039
Echinococcus multilocularis tachykinin peptides receptor 99D 0.0034 0.0067 0.0255
Treponema pallidum NADH oxidase 0.0148 0.0493 0.2752
Trypanosoma cruzi cytochrome P450, putative 0.0026 0.0037 0.0036
Echinococcus granulosus orexin receptor type 2 0.0034 0.0067 0.0243
Schistosoma mansoni peptide (allatostatin)-like receptor 0.0034 0.0067 0.0132
Echinococcus granulosus retinoic acid receptor rxr beta a 0.0101 0.0318 0.1178
Onchocerca volvulus 0.0082 0.0248 0.0961
Plasmodium falciparum FAD-linked sulfhydryl oxidase ERV1, putative 0.0034 0.0066 0.0418
Loa Loa (eye worm) hypothetical protein 0.0081 0.0241 0.0237
Loa Loa (eye worm) excitatory GABA receptor EXP-1A 0.0039 0.0085 0.0081
Loa Loa (eye worm) hypothetical protein 0.0101 0.0318 0.0314
Brugia malayi nuclear receptor NHR-67 0.0048 0.0117 0.0117
Loa Loa (eye worm) PHD-finger family protein 0.0021 0.0017 0.0013
Trichomonas vaginalis dihydrolipoamide dehydrogenase, putative 0.0039 0.0085 0.0325
Echinococcus granulosus 7tm_1 domain containing protein 0.0034 0.0067 0.0243
Echinococcus multilocularis lipoxygenase domain containing protein 0.0039 0.0084 0.0325
Onchocerca volvulus 0.0101 0.0318 0.1234
Schistosoma mansoni hypothetical protein 0.0039 0.0085 0.0168
Trichomonas vaginalis conserved hypothetical protein 0.0033 0.0061 0.0231
Trypanosoma cruzi aldehyde dehydrogenase, putative 0.0027 0.0039 0.0037
Brugia malayi nuclear receptor NHR-88 0.0101 0.0318 0.0318
Mycobacterium tuberculosis Putative ferredoxin reductase 0.0971 0.3593 0.8979
Loa Loa (eye worm) histone methyltransferase 0.0048 0.0118 0.0113
Loa Loa (eye worm) hypothetical protein 0.0018 0.0006 0.0001
Echinococcus granulosus peptide allatostatin:somatostatin 0.0034 0.0067 0.0243
Schistosoma mansoni serine/threonine protein kinase 0.0021 0.0015 0.0029
Loa Loa (eye worm) hypothetical protein 0.0034 0.0067 0.0062
Brugia malayi Cytochrome P450 family protein 0.0037 0.0076 0.0076
Onchocerca volvulus 0.0034 0.0067 0.0258
Toxoplasma gondii pyruvate dehydrogenase complex subunit PDH-E3II 0.0148 0.0493 0.2761
Mycobacterium ulcerans epimerase 0.002 0.0011 0.0037
Loa Loa (eye worm) nuclear receptor nhr-7B 0.0048 0.0117 0.0113
Toxoplasma gondii aldehyde dehydrogenase 0.0488 0.1773 1
Brugia malayi nuclear hormone receptor family member odr-7 0.0048 0.0117 0.0117
Echinococcus multilocularis bromodomain adjacent to zinc finger domain 0.0037 0.0077 0.0294
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0125 0.0409 0.0408
Plasmodium falciparum cysteine proteinase falcipain 2a 0.0033 0.0061 0.039
Loa Loa (eye worm) ACC-1 protein 0.0039 0.0085 0.0081
Mycobacterium ulcerans hypothetical protein 0.002 0.0011 0.0037
Brugia malayi hypothetical protein 0.0018 0.0006 0.0006
Schistosoma mansoni mixed-lineage leukemia protein mll 0.031 0.1103 0.2186
Loa Loa (eye worm) hypothetical protein 0.0034 0.0067 0.0062
Trichomonas vaginalis conserved hypothetical protein 0.0033 0.0061 0.0231
Schistosoma mansoni hepatocyte nuclear factor 4-alpha (hnf-4-alpha) 0.0048 0.0117 0.0232
Trypanosoma cruzi hypothetical protein, conserved 0.0039 0.0085 0.0084
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0034 0.0067 0.0132
Loa Loa (eye worm) hypothetical protein 0.0039 0.0085 0.0081
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0033 0.0061 0.0233
Trichomonas vaginalis mercuric reductase, putative 0.0148 0.0493 0.1908
Schistosoma mansoni SmCL2-like peptidase (C01 family) 0.0017 0.0001 0.0002
Trichomonas vaginalis CAMK family protein kinase 0.0471 0.1711 0.6635
Brugia malayi acetylcholine receptor alpha subunit precursor, putative 0.0039 0.0085 0.0085
Trichomonas vaginalis conserved hypothetical protein 0.0033 0.0061 0.0231
Echinococcus granulosus uncharacterized sodium dependent transporter 0.0081 0.0241 0.0892
Loa Loa (eye worm) intermediate filament protein 0.0082 0.0248 0.0243
Echinococcus multilocularis allatostatin A receptor 0.0034 0.0067 0.0255
Trypanosoma cruzi ERV/ALR sulfhydryl oxidase domain-containing protein 0.0034 0.0066 0.0064
Toxoplasma gondii NADH dehydrogenase (NDH2-II) 0.0039 0.0085 0.0454
Echinococcus multilocularis somatostatin receptor 0.0034 0.0067 0.0255
Brugia malayi Nuclear hormone receptor family member nhr-14 0.0101 0.0318 0.0318
Schistosoma mansoni loxhd1 0.0039 0.0084 0.0167
Loa Loa (eye worm) nicotinic acetylcholine receptor alpha subunit 0.0039 0.0085 0.0081
Schistosoma mansoni hypothetical protein 0.0034 0.0067 0.0132
Mycobacterium tuberculosis Probable aldehyde dehydrogenase 0.0488 0.1773 0.4425
Schistosoma mansoni photoreceptor-specific nuclear receptor related 0.0101 0.0318 0.063
Loa Loa (eye worm) cysteine protease 0.0033 0.0061 0.0057
Plasmodium falciparum LCCL domain-containing protein 0.0039 0.0084 0.0541
Echinococcus multilocularis cathepsin l cysteine peptidase 0.0033 0.0061 0.0234
Brugia malayi hypothetical protein 0.0034 0.0067 0.0067
Brugia malayi Cytochrome P450 family protein 0.0026 0.0037 0.0037
Schistosoma mansoni cpg binding protein 0.0155 0.052 0.103
Echinococcus granulosus neuropeptide FF receptor 2 0.0034 0.0067 0.0243
Schistosoma mansoni nAChR subunit 0.0039 0.0085 0.0169
Echinococcus multilocularis nAChR subunit 0.0021 0.0017 0.0062
Brugia malayi larval opioid receptor 0.0034 0.0067 0.0067
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0034 0.0067 0.0255
Echinococcus granulosus uncharacterized sodium dependent transporter 0.0081 0.0241 0.0892
Entamoeba histolytica aldehyde dehydrogenase 1, putative 0.0027 0.0039 0.0218
Trichomonas vaginalis conserved hypothetical protein 0.0033 0.0061 0.0231
Trypanosoma cruzi NADH dehydrogenase, putative 0.0039 0.0085 0.0084
Echinococcus granulosus pyridine nucleotide disulfide oxidoreductase 0.0039 0.0085 0.0311
Schistosoma mansoni aldehyde dehydrogenase 0.0027 0.0039 0.0076
Brugia malayi acetylcholine receptor, alpha-type subunit unc-38 precursor 0.0039 0.0085 0.0085
Echinococcus granulosus nuclear receptor nhr 48 0.0048 0.0117 0.0431
Onchocerca volvulus 0.0039 0.0085 0.033
Leishmania major C-8 sterol isomerase-like protein 0.2674 1 1
Schistosoma mansoni adenoreceptor 0.0034 0.0067 0.0132
Schistosoma mansoni nAChR subunit 0.0039 0.0085 0.0169
Loa Loa (eye worm) hypothetical protein 0.0018 0.0006 0.0001
Echinococcus multilocularis succinate semialdehyde dehydrogenase 0.0027 0.0039 0.0146
Mycobacterium tuberculosis Probable endonuclease IV End (endodeoxyribonuclease IV) (apurinase) 0.0074 0.0218 0.0533
Echinococcus multilocularis g protein linked acetylcholine receptor gar 2a 0.0034 0.0067 0.0255
Brugia malayi PXA domain containing protein 0.0019 0.0009 0.0009
Echinococcus multilocularis serine:threonine protein kinase PLK1 0.0471 0.1711 0.6679
Onchocerca volvulus 0.0033 0.0061 0.0237
Echinococcus multilocularis Regulator of G protein signaling 20 0.0019 0.0009 0.003
Brugia malayi putative neuropeptide receptor 0.0034 0.0067 0.0067
Plasmodium vivax multidomain scavenger receptor, putative 0.0039 0.0084 0.0541
Onchocerca volvulus 0.0034 0.0067 0.0258
Brugia malayi NADPH:adrenodoxin oxidoreductase, mitochondrial precursor 0.0039 0.0085 0.0085
Echinococcus multilocularis sodium dependent neurotransmitter transporter 0.0081 0.0241 0.0937
Onchocerca volvulus 0.0039 0.0084 0.0328
Trichomonas vaginalis conserved hypothetical protein 0.0019 0.0009 0.003
Schistosoma mansoni regulator of G protein signaling 0.0019 0.0009 0.0018
Brugia malayi nuclear receptor NHR-88 0.0048 0.0117 0.0117
Schistosoma mansoni coup transcription factor 0.0101 0.0318 0.063
Mycobacterium tuberculosis Probable aldehyde dehydrogenase NAD dependent AldA (aldehyde dehydrogenase [NAD+]) 0.0027 0.0039 0.0085
Onchocerca volvulus 0.0082 0.0248 0.0961
Echinococcus multilocularis neuropeptide Y receptor 0.0034 0.0067 0.0255
Brugia malayi acetylcholine receptor protein, alpha-like chain, putative 0.0039 0.0085 0.0085
Echinococcus granulosus cpg binding protein 0.0155 0.052 0.1929
Echinococcus multilocularis glycine receptor subunit alpha 1 0.0039 0.0085 0.0328
Mycobacterium ulcerans succinate-semialdehyde dehydrogenase [NADP+] dependent, GabD1 0.0027 0.0039 0.0192
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0101 0.0318 0.0318
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0034 0.0067 0.0132
Giardia lamblia Kinase, PLK 0.0471 0.1711 1
Echinococcus multilocularis rhodopsin orphan GPCR 0.0034 0.0067 0.0255
Loa Loa (eye worm) hypothetical protein 0.002 0.0011 0.0007
Brugia malayi hypothetical protein 0.0048 0.0117 0.0117
Loa Loa (eye worm) hypothetical protein 0.0082 0.0247 0.0243
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0034 0.0067 0.0132
Schistosoma mansoni nAChR subunit 0.0039 0.0085 0.0169
Loa Loa (eye worm) hypothetical protein 0.0034 0.0067 0.0062
Brugia malayi sulfakinin receptor protein 0.0034 0.0067 0.0067
Schistosoma mansoni neuropeptide F-like receptor 0.0034 0.0067 0.0132
Brugia malayi Dopamine receptor protein 2 0.0034 0.0067 0.0067
Brugia malayi nuclear hormone receptor 0.0048 0.0117 0.0117
Brugia malayi Nuclear hormone receptor-like 1 0.106 0.3926 0.3926
Toxoplasma gondii non-proton pumping type-II NADH dehydrogenase I 0.0039 0.0085 0.0454
Trypanosoma cruzi Lanosterol 14-alpha demethylase 0.0018 0.0005 0.0003
Loa Loa (eye worm) doublecortin family protein 0.0039 0.0084 0.008
Brugia malayi regulator of G-protein signaling rgs-7 0.0019 0.0009 0.0009
Brugia malayi photoreceptor-specific nuclear receptor 0.0101 0.0318 0.0318
Onchocerca volvulus 0.0033 0.0061 0.0237
Schistosoma mansoni aminoadipate-semialdehyde dehydrogenase 0.0082 0.0247 0.049
Loa Loa (eye worm) hypothetical protein 0.0039 0.0085 0.008
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0109 0.0347 0.0687
Echinococcus multilocularis Ankyrin repeat domain containing protein 0.0087 0.0266 0.1034
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0101 0.0318 0.0318
Schistosoma mansoni sulfide quinone reductase 0.0039 0.0085 0.0168
Loa Loa (eye worm) hypothetical protein 0.033 0.1179 0.1175
Entamoeba histolytica disulphide oxidoreductase, putative 0.0039 0.0085 0.0489
Loa Loa (eye worm) hypothetical protein 0.0034 0.0067 0.0062
Schistosoma mansoni retinoid-x-receptor (RXR) 0.0101 0.0318 0.063
Loa Loa (eye worm) hypothetical protein 0.0034 0.0067 0.0062
Echinococcus granulosus nicotinic acetylcholine receptor a11 subunit 0.0039 0.0085 0.0312
Loa Loa (eye worm) hypothetical protein 0.0034 0.0067 0.0062
Brugia malayi glutathione reductase 0.0426 0.154 0.154
Entamoeba histolytica hypothetical protein 0.0035 0.0068 0.0392
Schistosoma mansoni multiple ankyrin repeats single kh domain protein 0.0087 0.0266 0.0527
Echinococcus granulosus nuclear receptor subfamily 4 group A 0.0048 0.0117 0.0431
Brugia malayi Intermediate filament tail domain containing protein 0.0082 0.0248 0.0248
Brugia malayi Neurotransmitter-gated ion-channel ligand binding domain containing protein 0.0039 0.0085 0.0085
Loa Loa (eye worm) PLK/PLK1 protein kinase 0.0471 0.1711 0.1707
Loa Loa (eye worm) hypothetical protein 0.0048 0.0117 0.0113
Schistosoma mansoni nAChR subunit 0.0018 0.0006 0.0011
Trypanosoma cruzi delta-1-pyrroline-5-carboxylate dehydrogenase, putative 0.0027 0.0039 0.0037
Trypanosoma brucei dihydrolipoamide dehydrogenase 0.0148 0.0493 0.0492
Trichomonas vaginalis regulator of G protein signaling 5, rgs5, putative 0.0019 0.0009 0.003
Schistosoma mansoni regulator of G protein signaling 17 19 20 (rgs17 19 20) 0.0019 0.0009 0.0018
Echinococcus granulosus axis inhibition protein axin 0.0019 0.0009 0.0029
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0125 0.0409 0.0408
Trypanosoma brucei aldehyde dehydrogenase family, putative 0.0027 0.0039 0.0037
Onchocerca volvulus 0.0039 0.0085 0.033
Schistosoma mansoni cellular tumor antigen P53 0.0049 0.0122 0.0241
Loa Loa (eye worm) neuropeptide F receptor 0.0034 0.0067 0.0062
Schistosoma mansoni nuclear receptor 2DBD-gamma 0.0101 0.0318 0.063
Trichomonas vaginalis succinate semialdehyde dehydrogenase, putative 0.0027 0.0039 0.0145
Brugia malayi Augmenter of liver regeneration 0.0034 0.0066 0.0066
Schistosoma mansoni zinc finger protein 0.0048 0.0117 0.0232
Echinococcus granulosus sulfide:quinone oxidoreductase 0.0039 0.0085 0.0311
Brugia malayi alpha keto acid dehydrogenase complex, E3 component, lipoamide dehydrogenase 0.0108 0.0345 0.0345
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0033 0.0061 0.0233
Echinococcus multilocularis nuclear receptor subfamily 1 group D 0.0053 0.0139 0.0536
Echinococcus granulosus axis inhibition protein axin 0.0019 0.0009 0.0029
Echinococcus granulosus nicotinic acetylcholine receptor subunit type 0.0039 0.0085 0.0312
Toxoplasma gondii Sodium:neurotransmitter symporter family protein 0.0081 0.0241 0.1338
Echinococcus multilocularis rhodopsin orphan GPCR 0.0034 0.0067 0.0255
Brugia malayi G-protein coupled receptor 0.0034 0.0067 0.0067
Loa Loa (eye worm) fibroinase 0.0033 0.0061 0.0057
Schistosoma mansoni retinoic acid receptor RXR 0.0101 0.0318 0.063
Echinococcus multilocularis axis inhibition protein axin 0.0019 0.0009 0.003
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0033 0.0061 0.0233
Loa Loa (eye worm) hypothetical protein 0.0048 0.0117 0.0113
Treponema pallidum thioredoxin reductase (trxB) 0.0039 0.0085 0.0354
Loa Loa (eye worm) G-protein-linked acetylcholine receptor protein 2 0.0034 0.0067 0.0062
Onchocerca volvulus Nuclear receptor subfamily 6 group A member 1 homolog 0.0048 0.0117 0.0454
Brugia malayi SET domain containing protein 0.0017 0.0003 0.0003
Trypanosoma cruzi Present in the outer mitochondrial membrane proteome 4 0.0034 0.0066 0.0064
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0033 0.0061 0.0233
Echinococcus multilocularis Nuclear hormone receptor family member nhr 41 0.0101 0.0318 0.1238
Loa Loa (eye worm) hypothetical protein 0.0021 0.0017 0.0012
Echinococcus multilocularis serotonin receptor 0.0286 0.1013 0.3951
Plasmodium vivax holo-[acyl-carrier-protein] synthase, putative 0.0023 0.0025 0.0152
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0101 0.0318 0.1178
Echinococcus multilocularis Mitotic checkpoint protein PRCC, C terminal 0.0506 0.1842 0.7192
Trypanosoma brucei dihydrolipoyl dehydrogenase 0.0148 0.0493 0.0492
Plasmodium vivax SET domain protein, putative 0.0091 0.0281 0.1816
Loa Loa (eye worm) hypothetical protein 0.0018 0.0006 0.0001
Onchocerca volvulus 0.0022 0.002 0.0079
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0091 0.0281 0.0556
Leishmania major 2-oxoglutarate dehydrogenase, e3 component, lipoamidedehydrogenase-like protein 0.0148 0.0493 0.0488
Schistosoma mansoni nAChR subunit 0.0039 0.0085 0.0169
Loa Loa (eye worm) hypothetical protein 0.0039 0.0084 0.008
Brugia malayi Neurotransmitter-gated ion-channel transmembrane region family protein 0.0021 0.0017 0.0017
Onchocerca volvulus 0.0034 0.0067 0.0258
Loa Loa (eye worm) Sodium:neurotransmitter symporter family protein 0.0081 0.0241 0.0237
Schistosoma mansoni thyroid hormone receptor 0.0607 0.2223 0.4404
Brugia malayi Dopamine receptor protein 1, putative (partial) 0.0034 0.0067 0.0067
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0022 0.002 0.0074
Loa Loa (eye worm) hypothetical protein 0.0034 0.0067 0.0062
Loa Loa (eye worm) hypothetical protein 0.0034 0.0067 0.0062
Trypanosoma cruzi aldehyde dehydrogenase family, putative 0.0027 0.0039 0.0037
Loa Loa (eye worm) hypothetical protein 0.0048 0.0117 0.0113
Onchocerca volvulus Nuclear receptor subfamily 6 group A member 1 homolog 0.0048 0.0117 0.0454
Leishmania major acetoin dehydrogenase e3 component-like protein 0.0148 0.0493 0.0488
Echinococcus granulosus serine:threonine protein kinase PLK1 0.0471 0.1711 0.6358
Loa Loa (eye worm) hypothetical protein 0.0021 0.0017 0.0012
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0125 0.0409 0.0408
Echinococcus granulosus nuclear factor of activated T cells 5 0.0073 0.0212 0.0783
Trypanosoma cruzi 2,4-dienoyl-coa reductase fadh1, putative 0.0039 0.0085 0.0084
Brugia malayi Sodium:neurotransmitter symporter family protein 1, putative 0.0081 0.0241 0.0241
Echinococcus multilocularis alpha 1A adrenergic receptor 0.0034 0.0067 0.0255
Echinococcus multilocularis retinoic acid receptor rxr beta a retinoic acid receptor rxr alpha a retinoic acid receptor rxr alpha 0.0048 0.0117 0.0452
Toxoplasma gondii NADP-dependent succinate-semialdehyde dehydrogenase 0.0027 0.0039 0.0192
Loa Loa (eye worm) hypothetical protein 0.0048 0.0117 0.0113
Schistosoma mansoni biogenic amine (5HT) receptor 0.0034 0.0067 0.0132
Schistosoma mansoni hypothetical protein 0.0018 0.0005 0.0009
Entamoeba histolytica hypothetical protein 0.0035 0.0068 0.0392
Brugia malayi Hypothetical glycine receptor like protein T20B12.9 in chromosome III 0.0039 0.0085 0.0085
Echinococcus multilocularis lamin dm0 0.0082 0.0248 0.0964
Echinococcus granulosus rhodopsin orphan GPCR 0.0034 0.0067 0.0243
Echinococcus multilocularis neuronal acetylcholine receptor subunit alpha 4 0.0039 0.0085 0.0328
Trypanosoma cruzi polo-like protein kinase, putative 0.0471 0.1711 0.171
Schistosoma mansoni sulfide quinone reductase 0.0039 0.0085 0.0168
Leishmania major dihydrolipoamide dehydrogenase, putative 0.0148 0.0493 0.0488
Trichomonas vaginalis conserved hypothetical protein 0.0029 0.0045 0.0171
Schistosoma mansoni hypothetical protein 0.0035 0.0068 0.0135
Echinococcus multilocularis nAChR subunit 0.0039 0.0085 0.0328
Echinococcus multilocularis orexin receptor type 2 0.0034 0.0067 0.0255
Loa Loa (eye worm) hypothetical protein 0.0039 0.0085 0.0081
Trichomonas vaginalis disulfide oxidoreductase, putative 0.0039 0.0085 0.0325
Mycobacterium leprae PROBABLE NADH DEHYDROGENASE NDH 0.0971 0.3593 0.8979
Loa Loa (eye worm) hypothetical protein 0.0053 0.0139 0.0134
Onchocerca volvulus 0.0018 0.0006 0.0022
Onchocerca volvulus 0.0021 0.0017 0.0066
Brugia malayi Bromodomain containing protein 0.0085 0.0259 0.0259
Schistosoma mansoni opsin-like receptor 0.0034 0.0067 0.0132
Echinococcus multilocularis Nuclear hormone receptor HR96 0.0048 0.0117 0.0452
Trypanosoma brucei hypothetical protein, conserved 0.0039 0.0085 0.0084
Echinococcus granulosus neuropeptide s receptor 0.0034 0.0067 0.0243
Brugia malayi Serotonin receptor 0.0034 0.0067 0.0067
Echinococcus multilocularis cathepsin l cysteine peptidase 0.0033 0.0061 0.0234
Mycobacterium tuberculosis Probable reductase 0.0971 0.3593 0.8979
Trypanosoma brucei 2,4-dienoyl-coa reductase-like protein 0.0039 0.0085 0.0084
Echinococcus multilocularis cytoplasmic intermediate filament protein 0.004 0.0087 0.0336
Loa Loa (eye worm) hypothetical protein 0.0053 0.0139 0.0134
Brugia malayi hypothetical protein 0.0039 0.0084 0.0084
Mycobacterium tuberculosis Probable dehydrogenase 0.0971 0.3593 0.8979
Mycobacterium tuberculosis Probable NADH-dependent glutamate synthase (small subunit) GltD (L-glutamate synthase) (L-glutamate synthetase) (NADH-glutamate 0.0039 0.0085 0.0201
Echinococcus granulosus sodium dependent neurotransmitter transporter 0.0081 0.0241 0.0892
Leishmania major cathepsin L-like protease 0.0033 0.0061 0.0057
Echinococcus granulosus growth hormone secretagogue receptor type 1 0.0034 0.0067 0.0243
Schistosoma mansoni regulator of G protein signaling 0.0019 0.0009 0.0018
Toxoplasma gondii NADPH-glutathione reductase 0.0148 0.0493 0.2761
Loa Loa (eye worm) hypothetical protein 0.0039 0.0085 0.0081
Mycobacterium ulcerans NADPH:adrenodoxin oxidoreductase FprA 0.0039 0.0085 0.0454
Schistosoma mansoni neuropeptide f receptor 76f 0.0034 0.0067 0.0132
Entamoeba histolytica glutamate synthase beta subunit, putative 0.0039 0.0085 0.0489
Loa Loa (eye worm) hypothetical protein 0.0018 0.0006 0.0001
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0125 0.0409 0.0408
Schistosoma mansoni glutamate synthase 0.0039 0.0085 0.0168
Brugia malayi Neurotransmitter-gated ion-channel ligand binding domain containing protein 0.0039 0.0085 0.0085
Brugia malayi Cation transporter family protein 0.0039 0.0085 0.0085
Loa Loa (eye worm) hypothetical protein 0.0018 0.0006 0.0001
Mycobacterium ulcerans NADH dehydrogenase Ndh 0.0039 0.0085 0.0454
Schistosoma mansoni cytochrome P450 0.0018 0.0005 0.0009
Echinococcus multilocularis sodium and chloride dependent glycine 0.0081 0.0241 0.0937
Brugia malayi hypothetical protein 0.0035 0.0068 0.0068
Plasmodium falciparum apurinic/apyrimidinic endonuclease Apn1, putative 0.0074 0.0218 0.1406
Echinococcus granulosus serotonin transporter 0.0475 0.1726 0.6413
Echinococcus multilocularis glycine receptor subunit beta 0.0039 0.0085 0.0328
Echinococcus granulosus nicotinic acetylcholine receptor alpha subunit 0.0039 0.0085 0.0312
Loa Loa (eye worm) 5-hydroxytryptamine 2C receptor 0.0034 0.0067 0.0062
Echinococcus granulosus rhodopsin orphan GPCR 0.0034 0.0067 0.0243
Echinococcus multilocularis Basic leucine zipper (bZIP) transcription 0.0035 0.0068 0.0262
Mycobacterium tuberculosis Probable aldehyde dehydrogenase 0.0027 0.0039 0.0085
Loa Loa (eye worm) nuclear hormone receptor family member nhr-31 0.0101 0.0318 0.0314
Mycobacterium tuberculosis Probable methylmalonate-semialdehyde dehydrogenase MmsA (methylmalonic acid semialdehyde dehydrogenase) (MMSDH) 0.0027 0.0039 0.0085
Schistosoma mansoni nuclear receptor 0.0048 0.0117 0.0232
Echinococcus multilocularis serotonin transporter 0.0475 0.1726 0.6736
Mycobacterium tuberculosis Dihydrolipoamide dehydrogenase LpdC (lipoamide reductase (NADH)) (lipoyl dehydrogenase) (dihydrolipoyl dehydrogenase) (diaphoras 0.108 0.4 1
Echinococcus multilocularis nicotinic acetylcholine receptor beta 1 subunit 0.0039 0.0085 0.0328
Onchocerca volvulus 0.0033 0.0061 0.0237
Echinococcus granulosus mixed lineage leukemia protein mll 0.0039 0.0085 0.0311
Brugia malayi glutamate-gated chloride channel alpha3A subunit, putative 0.0018 0.0006 0.0006
Brugia malayi glutamate synthase 0.0039 0.0085 0.0085
Entamoeba histolytica glutamate synthase beta subunit, putative 0.0039 0.0085 0.0489
Loa Loa (eye worm) hypothetical protein 0.0053 0.0139 0.0134
Echinococcus multilocularis thyroid hormone receptor alpha 0.0607 0.2223 0.8678
Loa Loa (eye worm) hypothetical protein 0.0027 0.0039 0.0034
Echinococcus multilocularis Cys loop ligand gated ion channel subunit 0.0039 0.0085 0.0328
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0044 0.0102 0.0393
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0034 0.0067 0.0255
Onchocerca volvulus Putative nachr subunit 0.0039 0.0085 0.033
Echinococcus granulosus 5'partial|histone lysine N methyltransferase SETDB2 0.0085 0.0257 0.095
Trichomonas vaginalis dihydroorotate dehydrogenase, putative 0.0039 0.0085 0.0325
Schistosoma mansoni aldehyde dehydrogenase 0.0027 0.0039 0.0076
Echinococcus granulosus cathepsin l cysteine peptidase 0.0033 0.0061 0.0223
Brugia malayi Regulator of G protein signaling domain containing protein 0.0019 0.0009 0.0009
Schistosoma mansoni regulator of G protein signaling 0.0019 0.0009 0.0018
Loa Loa (eye worm) hypothetical protein 0.0019 0.0009 0.0004
Loa Loa (eye worm) cytochrome P450 family protein 0.0037 0.0076 0.0071
Loa Loa (eye worm) nicotinic acetylcholine receptor non-alpha subunit 0.0039 0.0085 0.0081
Loa Loa (eye worm) hypothetical protein 0.0034 0.0067 0.0062
Schistosoma mansoni muscarinic acetylcholine (GAR) receptor 0.0034 0.0067 0.0132
Echinococcus multilocularis ecdysone induced protein 78C 0.0101 0.0318 0.1238
Schistosoma mansoni cpg binding protein 0.0145 0.0481 0.0954
Plasmodium falciparum ferrodoxin reductase-like protein 0.0039 0.0085 0.0544
Loa Loa (eye worm) hypothetical protein 0.0042 0.0095 0.0091
Onchocerca volvulus 0.0039 0.0085 0.0329
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0125 0.0409 0.0408
Loa Loa (eye worm) hypothetical protein 0.0022 0.002 0.0016
Echinococcus granulosus cytochrome P450 2K1 0.0018 0.0005 0.0012
Echinococcus multilocularis nuclear factor of activated T cells 5 0.0073 0.0212 0.0823
Mycobacterium ulcerans aldehyde dehydrogenase 0.0027 0.0039 0.0192
Schistosoma mansoni hypothetical protein 0.05 0.1819 0.3604
Entamoeba histolytica hypothetical protein 0.0023 0.0025 0.0137
Schistosoma mansoni sodium/chloride dependent neurotransmitter transporter 0.0081 0.0241 0.0478
Loa Loa (eye worm) hypothetical protein 0.033 0.1179 0.1175
Trypanosoma brucei NADPH:adrenodoxin oxidoreductase, mitochondrial, putative 0.0039 0.0085 0.0084
Loa Loa (eye worm) hypothetical protein 0.0101 0.0318 0.0314
Brugia malayi RE15519p 0.0034 0.0067 0.0067
Echinococcus multilocularis cathepsin L cysteine protease 0.0033 0.0061 0.0234
Leishmania major cathepsin L-like protease 0.0033 0.0061 0.0057
Schistosoma mansoni biogenic amine (5HT) receptor 0.0286 0.1013 0.2007
Echinococcus multilocularis zinc finger protein 0.0028 0.0044 0.0168
Schistosoma mansoni glutamate synthase 0.0039 0.0085 0.0168
Loa Loa (eye worm) hypothetical protein 0.0475 0.1726 0.1722
Echinococcus multilocularis 0.0018 0.0005 0.0013
Onchocerca volvulus 0.0081 0.0241 0.0935
Trypanosoma cruzi major cysteine proteinase, putative 0.0098 0.0308 0.0307
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0125 0.0409 0.0408
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0044 0.0102 0.0393
Schistosoma mansoni methyl-cpg binding protein mbd 0.0018 0.0004 0.0007
Schistosoma mansoni chromodomain helicase DNA binding protein 0.0021 0.0018 0.0035
Echinococcus granulosus histone lysine methyltransferase setb 0.0109 0.0347 0.1285
Loa Loa (eye worm) hypothetical protein 0.0034 0.0067 0.0062
Trichomonas vaginalis disulfide oxidoreductase, putative 0.0039 0.0085 0.0325
Loa Loa (eye worm) hypothetical protein 0.0109 0.0347 0.0342
Mycobacterium tuberculosis Probable gamma-glutamyl phosphate reductase protein ProA (GPR) (glutamate-5-semialdehyde dehydrogenase) (glutamyl-gamma-semialde 0.0027 0.0039 0.0085
Echinococcus granulosus Mitotic checkpoint protein PRCC C terminal 0.0506 0.1842 0.6847
Echinococcus granulosus glycine receptor subunit beta 0.0039 0.0085 0.0312
Schistosoma mansoni amine GPCR 0.0034 0.0067 0.0132
Wolbachia endosymbiont of Brugia malayi NADPH-dependent glutamate synthase beta chain 0.0039 0.0085 0.1287
Schistosoma mansoni axis inhibition protein axin 0.0019 0.0009 0.0018
Brugia malayi ecdysteroid receptor 0.0101 0.0318 0.0318
Mycobacterium ulcerans dihydrolipoamide dehydrogenase, LpdB 0.0148 0.0493 0.2761
Trypanosoma brucei aldehyde dehydrogenase, putative 0.0027 0.0039 0.0037
Echinococcus granulosus rhodopsin orphan GPCR 0.0034 0.0067 0.0243
Echinococcus multilocularis g-protein coupled receptor 0.0034 0.0067 0.0255
Loa Loa (eye worm) solute carrier family 6 member 4 0.0475 0.1726 0.1722
Loa Loa (eye worm) hypothetical protein 0.0034 0.0067 0.0062
Mycobacterium ulcerans cytochrome P450 185A4 Cyp185A4 0.0026 0.0037 0.0185
Trypanosoma brucei dihydrolipoamide dehydrogenase, point mutation 0.0148 0.0493 0.0492
Echinococcus granulosus fetal alzheimer antigen falz 0.0031 0.0056 0.0203
Schistosoma mansoni SmCL2-like peptidase (C01 family) 0.0017 0.0001 0.0002
Echinococcus multilocularis regulator of G protein signaling 7 0.0019 0.0009 0.003
Trypanosoma cruzi pyrroline-5-carboxylate synthetase-like protein, putative 0.0027 0.0039 0.0037
Schistosoma mansoni rab6-interacting 0.0039 0.0084 0.0167
Loa Loa (eye worm) CYP4Cod1 0.0026 0.0037 0.0033
Schistosoma mansoni disulfide oxidoreductase 0.0039 0.0085 0.0168
Schistosoma mansoni multiple ankyrin repeats single kh domain protein 0.0087 0.0266 0.0527
Echinococcus multilocularis nicotinic acetylcholine receptor a11 subunit 0.0039 0.0085 0.0328
Leishmania major phosphopantetheinyl transferase-like protein 0.0023 0.0025 0.002
Onchocerca volvulus 0.0039 0.0085 0.033
Echinococcus multilocularis beta adrenergic receptor kinase 0.0021 0.0015 0.0053
Brugia malayi Neuronal acetylcholine receptor protein, alpha-2 chain precursor 0.0018 0.0006 0.0006
Brugia malayi hypothetical protein 0.0034 0.0067 0.0067
Loa Loa (eye worm) intermediate filament tail domain-containing protein 0.0082 0.0248 0.0243
Brugia malayi Sodium:neurotransmitter symporter family protein 0.0081 0.0241 0.0241
Echinococcus multilocularis mixed lineage leukemia protein mll 0.0039 0.0085 0.0327
Trichomonas vaginalis conserved hypothetical protein 0.0033 0.0061 0.0231
Brugia malayi Serotonin/octopamine receptor family protein 7 0.033 0.1179 0.1179
Echinococcus granulosus sodium:chloride dependent neurotransmitter 0.0081 0.0241 0.0892
Echinococcus multilocularis neuropeptide receptor 0.0034 0.0067 0.0255
Echinococcus granulosus tm gpcr rhodopsin 0.0034 0.0067 0.0243
Onchocerca volvulus 0.0081 0.0241 0.0935
Echinococcus granulosus FTZ F1 nuclear receptor protein 0.0101 0.0318 0.1178
Mycobacterium ulcerans short-chain type dehydrogenase/reductase 0.0061 0.0165 0.091
Toxoplasma gondii hypothetical protein 0.0081 0.0241 0.1338
Loa Loa (eye worm) hypothetical protein 0.0039 0.0085 0.0081
Echinococcus granulosus g protein coupled receptor 0.0034 0.0067 0.0243
Entamoeba histolytica pyridine nucleotide-disulfide oxidoreductase family protein 0.0039 0.0085 0.0489
Loa Loa (eye worm) hypothetical protein 0.0019 0.0009 0.0004
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0026 0.0036 0.0136
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0148 0.0493 0.0492
Loa Loa (eye worm) hypothetical protein 0.0018 0.0006 0.0001
Echinococcus granulosus methyl CpG binding domain protein 2 0.0018 0.0004 0.0009
Chlamydia trachomatis dihydrolipoyl dehydrogenase 0.0148 0.0493 1
Entamoeba histolytica cysteine proteinase, putative 0.0033 0.0061 0.0351
Echinococcus granulosus glutamate synthase 0.0039 0.0085 0.0311
Echinococcus multilocularis RUN 0.0039 0.0084 0.0325
Echinococcus multilocularis pyridine nucleotide disulfide oxidoreductase 0.0039 0.0085 0.0327
Toxoplasma gondii Sodium:neurotransmitter symporter family protein 0.0081 0.0241 0.1338
Echinococcus granulosus RUN 0.0039 0.0084 0.0309
Echinococcus granulosus dihydropyrimidine dehydrogenase NADP 0.0039 0.0085 0.0311
Mycobacterium leprae Probable NADH-dependent glutamate synthase (small subunit) GltD (L-glutamate synthase) (L-glutamate synthetase) (NADH-glutamate 0.0039 0.0085 0.0201
Schistosoma mansoni histamine h1 receptor 0.0034 0.0067 0.0132
Loa Loa (eye worm) RecQ helicase 0.0021 0.0015 0.0011
Echinococcus multilocularis aldehyde dehydrogenase, mitochondrial 0.0488 0.1773 0.692
Schistosoma mansoni kinase 0.024 0.0839 0.1662
Loa Loa (eye worm) hypothetical protein 0.0034 0.0067 0.0062
Plasmodium falciparum dihydrolipoyl dehydrogenase, mitochondrial 0.0148 0.0493 0.3195
Schistosoma mansoni histamine-responsive GPCR (AAF21638) 0.0034 0.0067 0.0132
Mycobacterium tuberculosis Probable pyrroline-5-carboxylate dehydrogenase RocA 0.0027 0.0039 0.0085
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0034 0.0067 0.0132
Leishmania major aldehyde dehydrogenase, putative 0.0027 0.0039 0.0034
Mycobacterium ulcerans sugar phosphate isomerases/epimerases 0.002 0.0011 0.0037
Onchocerca volvulus 0.0034 0.0067 0.0258
Echinococcus multilocularis aldehyde dehydrogenase family 3 member B1 0.0027 0.0039 0.0146
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0033 0.0061 0.0233
Mycobacterium ulcerans ferredoxin reductase 0.0039 0.0085 0.0454
Mycobacterium ulcerans pyrroline-5-carboxylate dehydrogenase, RocA 0.0027 0.0039 0.0192
Schistosoma mansoni Cys-loop ligand gated ion channel subunit 0.0039 0.0085 0.0169
Wolbachia endosymbiont of Brugia malayi dihydrolipoamide dehydrogenase E3 component 0.0148 0.0493 1
Brugia malayi Neurotransmitter-gated ion-channel transmembrane region family protein 0.0021 0.0017 0.0017
Echinococcus granulosus biogenic amine 5HT receptor 0.0034 0.0067 0.0243
Echinococcus multilocularis succinate semialdehyde dehydrogenase 0.0027 0.0039 0.0146
Echinococcus granulosus cathepsin l1 0.0033 0.0061 0.0223
Trypanosoma cruzi delta-1-pyrroline-5-carboxylate dehydrogenase, putative 0.0027 0.0039 0.0037
Brugia malayi neuropeptide F receptor 0.0034 0.0067 0.0067
Schistosoma mansoni serine/threonine protein kinase 0.0021 0.0015 0.0029
Trichomonas vaginalis hypothetical protein 0.0018 0.0004 0.0009
Brugia malayi hypothetical protein 0.0053 0.0139 0.0139
Onchocerca volvulus 0.0702 0.2579 1
Trypanosoma cruzi 2,4-dienoyl-coa reductase-like protein, putative 0.0039 0.0085 0.0084
Onchocerca volvulus 0.0098 0.0307 0.1193
Plasmodium falciparum glutathione reductase 0.0148 0.0493 0.3195
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0101 0.0318 0.1238
Brugia malayi steroid hormone receptor 0.0101 0.0318 0.0318
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0048 0.0117 0.0452
Schistosoma mansoni sodium/chloride dependent transporter 0.0082 0.0247 0.0489
Onchocerca volvulus 0.0033 0.0061 0.0237
Loa Loa (eye worm) hypothetical protein 0.0039 0.0085 0.0081
Loa Loa (eye worm) nuclear hormone receptor-like 1 0.1012 0.3746 0.3744
Plasmodium falciparum holo-[acyl-carrier-protein] synthase, putative 0.0023 0.0025 0.0152
Loa Loa (eye worm) programmed cell death 8 0.0039 0.0085 0.008
Schistosoma mansoni sodium/chloride dependent neurotransmitter transporter 0.0081 0.0241 0.0478
Brugia malayi Serotonin receptor 0.0494 0.1797 0.1797
Mycobacterium tuberculosis Possible succinate-semialdehyde dehydrogenase [NADP+] dependent (SSDH) GabD2 0.0027 0.0039 0.0085
Brugia malayi hypothetical protein 0.0019 0.0009 0.0009
Echinococcus granulosus allatostatin A receptor 0.0034 0.0067 0.0243
Plasmodium vivax apurinic/apyrimidinic endonuclease Apn1, putative 0.0074 0.0218 0.1406
Echinococcus granulosus tumor protein p63 0.0335 0.1197 0.4445
Onchocerca volvulus 0.0034 0.0067 0.0258
Onchocerca volvulus 0.0034 0.0067 0.0258
Echinococcus granulosus COUP TF:Svp nuclear hormone receptor 0.0101 0.0318 0.1178
Trichomonas vaginalis conserved hypothetical protein 0.0033 0.0061 0.0231
Schistosoma mansoni hypothetical protein 0.0027 0.0039 0.0076
Loa Loa (eye worm) nuclear hormone receptor family member nhr-14 0.0101 0.0318 0.0314
Loa Loa (eye worm) ctsf protein 0.0033 0.0061 0.0057
Brugia malayi hypothetical protein 0.0098 0.0308 0.0308
Loa Loa (eye worm) hypothetical protein 0.0039 0.0084 0.008
Echinococcus multilocularis neuropeptide Y receptor 0.0034 0.0067 0.0255
Giardia lamblia NADH oxidase lateral transfer candidate 0.0148 0.0493 0.2716
Schistosoma mansoni sodium-dependent neurotransmitter transporter 0.0081 0.0241 0.0478
Loa Loa (eye worm) glutathione reductase 0.0426 0.154 0.1536
Loa Loa (eye worm) hypothetical protein 0.0081 0.0241 0.0237
Entamoeba histolytica hypothetical protein 0.0019 0.0009 0.0045
Brugia malayi AKH receptor 0.0034 0.0067 0.0067
Brugia malayi Cation transporter family protein 0.0039 0.0085 0.0085
Brugia malayi cytochrome P450 0.0018 0.0005 0.0005
Brugia malayi follicle stimulating hormone receptor 0.0034 0.0067 0.0067
Wolbachia endosymbiont of Brugia malayi dihydrolipoamide dehydrogenase E3 component 0.0148 0.0493 1
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0034 0.0067 0.0132
Schistosoma mansoni polycystin 1-related 0.0039 0.0084 0.0167
Brugia malayi Melatonin receptor type 1A 0.0034 0.0067 0.0067
Mycobacterium ulcerans short-chain type dehydrogenase/reductase 0.0061 0.0165 0.091
Schistosoma mansoni sodium/chloride dependent neurotransmitter transporter 0.0081 0.0241 0.0478
Loa Loa (eye worm) CHromoDomain protein family member 0.0021 0.0018 0.0013
Chlamydia trachomatis thioredoxin reductase 0.0039 0.0085 0.1287
Schistosoma mansoni biogenic amine receptor 0.0034 0.0067 0.0132
Loa Loa (eye worm) hypothetical protein 0.0101 0.0318 0.0314
Echinococcus granulosus nicotinic acetylcholine receptor beta 1 subunit 0.0039 0.0085 0.0312
Brugia malayi DNA-(Apurinic or apyrimidinic site) lyase 0.0074 0.0218 0.0218
Schistosoma mansoni axis inhibition protein axin 0.0019 0.0009 0.0018
Echinococcus granulosus Nuclear hormone receptor HR96 0.0048 0.0117 0.0431
Echinococcus granulosus rhodopsin orphan GPCR 0.0034 0.0067 0.0243
Mycobacterium ulcerans thioredoxin reductase TrxB2 0.0039 0.0085 0.0454
Loa Loa (eye worm) hypothetical protein 0.0034 0.0067 0.0062
Schistosoma mansoni neuropeptide receptor 0.0034 0.0067 0.0132
Plasmodium falciparum NAD(P)H-dependent glutamate synthase, putative 0.0039 0.0085 0.0544
Brugia malayi hypothetical protein 0.0039 0.0084 0.0084
Loa Loa (eye worm) hypothetical protein 0.0475 0.1726 0.1722
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0048 0.0117 0.0431
Echinococcus multilocularis rhodopsin orphan GPCR 0.0034 0.0067 0.0255
Schistosoma mansoni regulator of G protein signaling 0.0019 0.0009 0.0018
Leishmania major hypothetical protein, conserved 0.0039 0.0085 0.008
Trichomonas vaginalis set domain proteins, putative 0.0702 0.2578 1
Echinococcus multilocularis bloom syndrome protein 0.0021 0.0015 0.0056
Mycobacterium ulcerans dehydrogenase 0.0039 0.0085 0.0454
Brugia malayi hypothetical protein 0.0034 0.0067 0.0067
Entamoeba histolytica aldehyde-alcohol dehydrogenase 2, putative 0.0027 0.0039 0.0218
Brugia malayi hypothetical protein 0.0034 0.0067 0.0067
Brugia malayi CHD4 protein 0.0021 0.0018 0.0018
Mycobacterium ulcerans gamma-aminobutyraldehyde dehydrogenase 0.0027 0.0039 0.0192
Brugia malayi Tachykinin-like peptides receptor 99D 0.0034 0.0067 0.0067
Loa Loa (eye worm) LGC-31 protein 0.0039 0.0085 0.0081
Schistosoma mansoni cathepsin F (C01 family) 0.0033 0.0061 0.0121
Brugia malayi hypothetical protein 0.0034 0.0067 0.0067
Echinococcus multilocularis dihydropyrimidine dehydrogenase (NADP+) 0.0039 0.0085 0.0327
Loa Loa (eye worm) hypothetical protein 0.0039 0.0085 0.0081
Loa Loa (eye worm) DR-78 0.0048 0.0117 0.0113
Entamoeba histolytica hypothetical protein 0.0035 0.0068 0.0392
Trichomonas vaginalis Clan CA, family C1, cathepsin L or K-like cysteine peptidase 0.0033 0.0061 0.0233
Trichomonas vaginalis conserved hypothetical protein 0.0019 0.0009 0.003
Plasmodium vivax type II NADH:ubiquinone oxidoreductase, putative 0.0039 0.0085 0.0544
Echinococcus granulosus neuropeptides capa receptor 0.0034 0.0067 0.0243
Loa Loa (eye worm) hypothetical protein 0.0098 0.0307 0.0303
Plasmodium falciparum glutathione reductase 0.0426 0.154 1
Plasmodium falciparum thioredoxin reductase 0.0426 0.154 1
Loa Loa (eye worm) hypothetical protein 0.0034 0.0067 0.0062
Echinococcus multilocularis rhodopsin orphan GPCR 0.0034 0.0067 0.0255
Echinococcus granulosus tachykinin peptides receptor 99D 0.0034 0.0067 0.0243
Loa Loa (eye worm) hypothetical protein 0.0021 0.0017 0.0012
Schistosoma mansoni amine GPCR 0.0034 0.0067 0.0132
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0033 0.0061 0.0233
Onchocerca volvulus 0.0034 0.0067 0.0258
Brugia malayi F/Y-rich N-terminus family protein 0.0049 0.0123 0.0123
Brugia malayi Pyridine nucleotide-disulphide oxidoreductase family protein 0.0039 0.0085 0.0085
Loa Loa (eye worm) thioredoxin reductase 0.0426 0.154 0.1536
Entamoeba histolytica NAD(FAD)-dependent dehydrogenase, putative 0.0039 0.0085 0.0489
Onchocerca volvulus 0.0049 0.0122 0.0472
Schistosoma mansoni sodium-dependent neurotransmitter transporter 0.0081 0.0241 0.0478
Trypanosoma cruzi C-8 sterol isomerase, putative 0.2674 1 1
Trypanosoma brucei pyridine nucleotide-disulphide oxidoreductase, putative 0.0039 0.0085 0.0084
Brugia malayi G protein-coupled receptor 0.0034 0.0067 0.0067
Echinococcus multilocularis G protein coupled receptor 139 0.0034 0.0067 0.0255
Schistosoma mansoni Tr4/Tr2 (homologue) 0.0101 0.0318 0.063
Loa Loa (eye worm) hypothetical protein 0.0034 0.0067 0.0062
Onchocerca volvulus Bile acid receptor homolog 0.0101 0.0318 0.1234
Echinococcus granulosus nAChR subunit 0.0021 0.0017 0.0059
Echinococcus multilocularis FTZ F1 nuclear receptor protein 0.0101 0.0318 0.1238
Echinococcus granulosus nuclear receptor subfamily 1 group D 0.0053 0.0139 0.0511
Trypanosoma cruzi Present in the outer mitochondrial membrane proteome 4 0.0034 0.0066 0.0064
Trichomonas vaginalis CAMK family protein kinase 0.0233 0.0815 0.316
Toxoplasma gondii gamma-glutamyl phosphate reductase, putative 0.0027 0.0039 0.0192
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0125 0.0409 0.0408
Loa Loa (eye worm) hypothetical protein 0.0018 0.0006 0.0001
Echinococcus granulosus glycine receptor subunit alpha 1 0.0039 0.0085 0.0312
Echinococcus multilocularis serotonin receptor 0.0286 0.1013 0.3951
Schistosoma mansoni delta 1-pyrroline-5-carboxylate synthetase 0.0027 0.0039 0.0076
Loa Loa (eye worm) hypothetical protein 0.0073 0.0211 0.0207
Schistosoma mansoni hypothetical protein 0.0506 0.1842 0.365
Loa Loa (eye worm) hypothetical protein 0.0022 0.002 0.0016
Schistosoma mansoni peptide (FMRFamide/somatostatin)-like receptor 0.0034 0.0067 0.0132
Loa Loa (eye worm) hypothetical protein 0.004 0.0087 0.0083
Loa Loa (eye worm) hypothetical protein 0.0048 0.0117 0.0113
Brugia malayi Dopamine receptor 0.0034 0.0067 0.0067
Brugia malayi Regulator of G protein signaling domain containing protein 0.0019 0.0009 0.0009
Loa Loa (eye worm) hypothetical protein 0.0101 0.0318 0.0314
Schistosoma mansoni biogenic amine receptor 0.0034 0.0067 0.0132
Trichomonas vaginalis glutamate synthase, putative 0.0039 0.0085 0.0325
Schistosoma mansoni lamin 0.0082 0.0248 0.0491
Mycobacterium ulcerans phosphopantetheinyl transferase, PptII 0.0023 0.0025 0.0114
Loa Loa (eye worm) MH2 domain-containing protein 0.0118 0.0383 0.0379
Brugia malayi G-protein coupled receptor 0.0034 0.0067 0.0067
Loa Loa (eye worm) nuclear hormone receptor family member nhr-49 0.0101 0.0318 0.0314
Schistosoma mansoni norepinephrine/norepinephrine transporter 0.0081 0.0241 0.0478
Echinococcus granulosus arachidonate 5 lipoxygenase 0.0171 0.0583 0.2162
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0034 0.0067 0.0132
Mycobacterium ulcerans succinate-semialdehyde dehydrogenase 0.0027 0.0039 0.0192
Plasmodium vivax vivapain-2 0.0033 0.0061 0.039
Toxoplasma gondii aldehyde dehydrogenase (NAD) family protein 0.0027 0.0039 0.0192
Loa Loa (eye worm) hypothetical protein 0.0048 0.0117 0.0113
Mycobacterium leprae DIHYDROLIPOAMIDE DEHYDROGENASE LPD (LIPOAMIDE REDUCTASE (NADH)) (LIPOYL DEHYDROGENASE) (DIHYDROLIPOYL DEHYDROGENASE) (DIAPHORASE 0.108 0.4 1
Loa Loa (eye worm) ligand-Gated ion Channel family member 0.0039 0.0085 0.0081
Schistosoma mansoni myst-related protein 0.0019 0.0009 0.0018
Brugia malayi CXXC zinc finger family protein 0.0145 0.0481 0.0481
Entamoeba histolytica aldehyde-alcohol dehydrogenase 2, putative 0.0027 0.0039 0.0218
Plasmodium vivax dihydrolipoyl dehydrogenase, mitochondrial, putative 0.0148 0.0493 0.3195
Loa Loa (eye worm) bromodomain containing protein 0.0018 0.0006 0.0001
Trypanosoma cruzi Lanosterol 14-alpha demethylase 0.0018 0.0005 0.0003
Onchocerca volvulus 0.0018 0.0006 0.0022
Loa Loa (eye worm) aldehyde dehydrogenase 4 0.0027 0.0039 0.0034
Mycobacterium tuberculosis Probable thioredoxin reductase TrxB2 (TRXR) (TR) 0.0039 0.0085 0.0201
Echinococcus multilocularis tumor protein p63 0.0335 0.1197 0.4669
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0101 0.0318 0.0318
Echinococcus multilocularis neuropeptides capa receptor 0.0034 0.0067 0.0255
Toxoplasma gondii Erv1 / Alr family protein 0.0034 0.0066 0.0345
Brugia malayi Nuclear hormone receptor E75 0.0048 0.0117 0.0117
Plasmodium vivax thioredoxin reductase, putative 0.0426 0.154 1
Loa Loa (eye worm) hypothetical protein 0.0034 0.0067 0.0062
Loa Loa (eye worm) hypothetical protein 0.0048 0.0117 0.0113
Echinococcus multilocularis G-protein coupled receptor, putative 0.0034 0.0067 0.0255
Schistosoma mansoni neuropeptide F-like receptor 0.0034 0.0067 0.0132
Loa Loa (eye worm) papain family cysteine protease containing protein 0.0033 0.0061 0.0057
Loa Loa (eye worm) glutamate-gated chloride channel alpha3A subunit 0.0039 0.0085 0.0081
Loa Loa (eye worm) hypothetical protein 0.0034 0.0067 0.0062
Brugia malayi Pre-SET motif family protein 0.0617 0.2259 0.2259
Loa Loa (eye worm) follicle stimulating hormone receptor 0.0034 0.0067 0.0062
Schistosoma mansoni rab6-interacting 0.0039 0.0084 0.0167
Schistosoma mansoni steroid hormone receptor ad4bp 0.0101 0.0318 0.063
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0101 0.0318 0.0318
Echinococcus multilocularis FTZ F1 alpha 0.0101 0.0318 0.1238
Mycobacterium ulcerans aldehyde dehydrogenase 0.0488 0.1773 1
Schistosoma mansoni neuropeptide receptor 0.0034 0.0067 0.0132
Echinococcus granulosus sodium and chloride dependent glycine 0.0081 0.0241 0.0892
Treponema pallidum gamma-glutamyl phosphate reductase 0.0027 0.0039 0.0081
Mycobacterium tuberculosis NADPH-dependent mycothiol reductase Mtr 0.0426 0.154 0.3842
Trichomonas vaginalis glutathione reductase, putative 0.0148 0.0493 0.1908
Echinococcus multilocularis sex peptide receptor 0.0034 0.0067 0.0255
Brugia malayi cathepsin L-like precursor 0.0022 0.002 0.002
Trichomonas vaginalis CAMK family protein kinase 0.0471 0.1711 0.6635
Loa Loa (eye worm) hypothetical protein 0.0018 0.0006 0.0001
Echinococcus multilocularis NADPH:adrenodoxin oxidoreductase 0.0039 0.0085 0.0327
Leishmania major 3-oxoacyl-(acyl-carrier protein) reductase, putative 0.0061 0.0165 0.0161
Onchocerca volvulus 0.0021 0.0017 0.0066
Mycobacterium leprae PROBABLE ALDEHYDE DEHYDROGENASE (NAD+) DEPENDENT 0.0027 0.0039 0.0085
Echinococcus granulosus expressed protein 0.037 0.1328 0.4935
Echinococcus granulosus thyrotropin releasing hormone receptor 0.0034 0.0067 0.0243
Schistosoma mansoni nuclear hormone receptor 0.0048 0.0117 0.0232
Loa Loa (eye worm) hypothetical protein 0.0027 0.0039 0.0034
Loa Loa (eye worm) hypothetical protein 0.0034 0.0067 0.0062
Trypanosoma brucei aldehyde dehydrogenase family, putative 0.0027 0.0039 0.0037
Mycobacterium tuberculosis Probable soluble pyridine nucleotide transhydrogenase SthA (STH) (NAD(P)(+) transhydrogenase [B-specific]) (nicotinamide nucleot 0.0148 0.0493 0.1222
Treponema pallidum oxidoreductase 0.0039 0.0085 0.0354
Echinococcus granulosus cathepsin l1 0.0022 0.002 0.0071
Brugia malayi conserved hypotetical protein 0.0048 0.0117 0.0117
Loa Loa (eye worm) hypothetical protein 0.0048 0.0117 0.0113
Onchocerca volvulus Cathepsin L homolog 0.0033 0.0061 0.0237
Mycobacterium ulcerans gamma-glutamyl phosphate reductase 0.0027 0.0039 0.0192
Schistosoma mansoni alpha-1 adrenergic receptor 0.0034 0.0067 0.0132
Echinococcus granulosus aldehyde dehydrogenase family 3 member B1 0.0027 0.0039 0.0139
Onchocerca volvulus Cathepsin L homolog 0.0033 0.0061 0.0237
Loa Loa (eye worm) hypothetical protein 0.0034 0.0067 0.0062
Onchocerca volvulus 0.0034 0.0067 0.0258
Toxoplasma gondii pyridine nucleotide-disulfide oxidoreductase domain-containing protein 0.0039 0.0085 0.0454
Echinococcus multilocularis fmrfamide receptor 0.0034 0.0067 0.0255
Loa Loa (eye worm) hypothetical protein 0.0034 0.0067 0.0062
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0033 0.0061 0.0233
Leishmania major protein kinase, putative,polo-like protein kinase, putative 0.0471 0.1711 0.1707
Trypanosoma cruzi pyridine nucleotide-disulphide oxidoreductase, putative 0.0039 0.0085 0.0084
Brugia malayi orphan nuclear receptor NR2E1 0.0048 0.0117 0.0117
Schistosoma mansoni nuclear hormone receptor nor-1/nor-2 0.0101 0.0318 0.063
Brugia malayi G-protein-linked acetylcholine receptor protein 2, putative 0.0034 0.0067 0.0067
Leishmania major hypothetical protein, conserved 0.0039 0.0085 0.008
Echinococcus granulosus intermediate filament protein 0.0082 0.0248 0.0917
Echinococcus multilocularis thioredoxin glutathione reductase 0.0426 0.154 0.601
Leishmania major trypanothione reductase 0.0426 0.154 0.1536
Schistosoma mansoni nicotinic acetylcholine receptor alpha 0.0021 0.0017 0.0034
Brugia malayi Probable G protein-coupled receptor kinase F19C6.1, putative 0.0021 0.0015 0.0015
Brugia malayi Nuclear hormone receptor family member nhr-41 0.0101 0.0318 0.0318
Brugia malayi Cathepsin L-like precursor 0.0033 0.0061 0.0061
Mycobacterium ulcerans glutamate synthase subunit beta 0.0039 0.0085 0.0454
Schistosoma mansoni sodium/chloride dependent transporter 0.0081 0.0241 0.0478
Schistosoma mansoni cathepsin F (C01 family) 0.0033 0.0061 0.0121
Echinococcus multilocularis Polycystic kidney disease protein 0.0039 0.0084 0.0325
Entamoeba histolytica hypothetical protein 0.0035 0.0068 0.0392
Trypanosoma cruzi trypanothione reductase, putative 0.0426 0.154 0.1539
Echinococcus multilocularis hepatocyte nuclear factor 4 alpha 0.0101 0.0318 0.1238
Loa Loa (eye worm) hypothetical protein 0.0034 0.0067 0.0062
Brugia malayi Cation transporter family protein 0.0039 0.0085 0.0085
Schistosoma mansoni glutamate synthase 0.0039 0.0085 0.0168
Onchocerca volvulus 0.0081 0.0241 0.0935
Mycobacterium leprae PROBABLE NADPH:ADRENODOXIN OXIDOREDUCTASE FPRB (ADRENODOXIN REDUCTASE) (AR) (FERREDOXIN-NADP(+) REDUCTASE) 0.0039 0.0085 0.0201
Brugia malayi Nuclear hormone receptor-like 1 0.1012 0.3746 0.3746
Onchocerca volvulus 0.0034 0.0067 0.0258
Loa Loa (eye worm) AGC/GRK/GRK protein kinase 0.0021 0.0015 0.001
Loa Loa (eye worm) Sodium:neurotransmitter symporter family protein 0.0081 0.0241 0.0237
Loa Loa (eye worm) pyridine nucleotide-disufhide oxidoreductase 0.0039 0.0085 0.008
Echinococcus multilocularis G protein coupled 5 hydroxytryptamine receptor 0.0034 0.0067 0.0255
Loa Loa (eye worm) unidentified vitellogenin-linked transcript protein 6 0.0034 0.0067 0.0062
Schistosoma mansoni z-protein (S1r protein) 0.0019 0.0009 0.0018
Schistosoma mansoni Cys-loop ligand gated ion channel subunit 0.0039 0.0085 0.0169
Mycobacterium tuberculosis Probable membrane NADH dehydrogenase NdhA 0.0971 0.3593 0.8979
Echinococcus multilocularis thyrotropin releasing hormone receptor 0.0034 0.0067 0.0255
Plasmodium falciparum cysteine proteinase falcipain 3 0.0033 0.0061 0.039
Echinococcus granulosus lipoxygenase domain containing protein 0.0039 0.0084 0.0309
Entamoeba histolytica serine/threonine protein kinase, putative 0.0471 0.1711 1
Leishmania major delta-1-pyrroline-5-carboxylate dehydrogenase, putative 0.0027 0.0039 0.0034
Loa Loa (eye worm) hypothetical protein 0.0034 0.0067 0.0062
Loa Loa (eye worm) hypothetical protein 0.0034 0.0067 0.0062
Entamoeba histolytica thioredoxin reductase, putative 0.0039 0.0085 0.0489
Loa Loa (eye worm) hypothetical protein 0.0101 0.0318 0.0314
Brugia malayi Thioredoxin reductase 0.0426 0.154 0.154
Trypanosoma cruzi cytochrome p450-like protein, putative 0.0018 0.0005 0.0003
Brugia malayi excitatory GABA receptor EXP-1A 0.0039 0.0085 0.0085
Echinococcus multilocularis sodium and chloride dependent glycine 0.0081 0.0241 0.0937
Echinococcus multilocularis apoptosis inducing factor 1 mitochondrial 0.0039 0.0085 0.0327
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0044 0.0102 0.0393
Onchocerca volvulus 0.0034 0.0067 0.0258
Brugia malayi Cathepsin L-like precursor 0.0033 0.0061 0.0061
Mycobacterium tuberculosis Conserved hypothetical protein 0.002 0.0011 0.0017
Brugia malayi Neurotransmitter-gated ion-channel ligand binding domain containing protein 0.0039 0.0085 0.0085
Schistosoma mansoni lipoxygenase 0.0171 0.0583 0.1154
Trypanosoma cruzi aldehyde dehydrogenase family, putative 0.0027 0.0039 0.0037
Plasmodium vivax dihydrolipoyl dehydrogenase, apicoplast, putative 0.0148 0.0493 0.3195
Schistosoma mansoni histone-lysine n-methyltransferase suv9 0.0102 0.0322 0.0639
Brugia malayi cytoplasmic intermediate filament protein 0.0044 0.0104 0.0104
Brugia malayi neuropeptide F receptor 0.0034 0.0067 0.0067
Echinococcus granulosus 3 hydroxyacyl coenzyme A dehydrogenase type 2 0.0061 0.0165 0.061
Loa Loa (eye worm) hypothetical protein 0.0101 0.0318 0.0314
Onchocerca volvulus 0.0475 0.1726 0.6693
Loa Loa (eye worm) hypothetical protein 0.0018 0.0006 0.0001
Mycobacterium ulcerans NAD-dependent aldehyde dehydrogenase AldA 0.0027 0.0039 0.0192
Loa Loa (eye worm) hypothetical protein 0.0034 0.0067 0.0062
Loa Loa (eye worm) hypothetical protein 0.0034 0.0067 0.0062
Trypanosoma cruzi cysteine peptidase, putative 0.0125 0.0409 0.0408
Loa Loa (eye worm) hypothetical protein 0.0034 0.0067 0.0062
Echinococcus granulosus histone lysine N methyltransferase MLL3 0.0039 0.0085 0.0311
Mycobacterium ulcerans piperideine-6-carboxilic acid dehydrogenase Pcd 0.0027 0.0039 0.0192
Toxoplasma gondii hypothetical protein 0.0081 0.0241 0.1338
Mycobacterium tuberculosis Succinate-semialdehyde dehydrogenase [NADP+] dependent (SSDH) GabD1 0.0027 0.0039 0.0085
Mycobacterium ulcerans succinate-semialdehyde dehydrogenase [NADP+] dependent, PutA_2 0.0027 0.0039 0.0192
Loa Loa (eye worm) hypothetical protein 0.0021 0.0017 0.0012
Toxoplasma gondii Erv1 / Alr family protein 0.0034 0.0066 0.0345
Trypanosoma cruzi hypothetical protein, conserved 0.0039 0.0085 0.0084
Entamoeba histolytica dihydropyrimidine dehydrogenase, putative 0.0039 0.0085 0.0489
Echinococcus multilocularis A kinase anchor protein 10, mitochondrial 0.0019 0.0009 0.003
Echinococcus multilocularis lipoxygenase domain containing protein 0.0039 0.0084 0.0325
Schistosoma mansoni retinoid-x-receptor (RXR) 0.0053 0.0139 0.0275
Onchocerca volvulus 0.0082 0.0247 0.0959
Loa Loa (eye worm) cytochrome P450 family protein 0.0026 0.0037 0.0033
Echinococcus multilocularis geminin 0.05 0.1819 0.7101
Brugia malayi glutamate-gated chloride channel alpha3A subunit, putative 0.0021 0.0017 0.0017
Loa Loa (eye worm) hypothetical protein 0.0081 0.0241 0.0237
Toxoplasma gondii endonuclease IV APN 0.0074 0.0218 0.1204
Brugia malayi Neurotransmitter-gated ion-channel transmembrane region family protein 0.0039 0.0085 0.0085
Loa Loa (eye worm) hypothetical protein 0.0049 0.0122 0.0117
Mycobacterium ulcerans endonuclease IV 0.0074 0.0218 0.1204
Brugia malayi aldehyde dehydrogenase 0.0027 0.0039 0.0039
Onchocerca volvulus 0.0048 0.0117 0.0454
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0033 0.0061 0.0233
Echinococcus granulosus thyroid hormone receptor alpha 0.0048 0.0117 0.0431
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0033 0.0061 0.0233
Loa Loa (eye worm) neuronal acetylcholine receptor protein 0.0018 0.0006 0.0001
Plasmodium vivax glutathione reductase, putative 0.0426 0.154 1
Mycobacterium ulcerans 4'-phosphopantetheinyl transferase 0.0023 0.0025 0.0114
Brugia malayi Nuclear hormone receptor family member nhr-31 0.0101 0.0318 0.0318
Loa Loa (eye worm) hypothetical protein 0.0034 0.0067 0.0062
Mycobacterium tuberculosis NADPH:adrenodoxin oxidoreductase FprA (NADPH-ferredoxin reductase) 0.0039 0.0085 0.0201
Echinococcus granulosus Fatty aldehyde dehydrogenase 0.0027 0.0039 0.0139
Schistosoma mansoni neuropeptide receptor 0.0034 0.0067 0.0132
Mycobacterium ulcerans aldehyde dehydrogenase 0.0488 0.1773 1
Brugia malayi serine/threonine-protein kinase plk-2 0.0471 0.1711 0.1711
Brugia malayi 3-hydroxyacyl-CoA dehydrogenase type II 0.0061 0.0165 0.0165
Brugia malayi hypothetical protein 0.0018 0.0006 0.0006
Loa Loa (eye worm) hypothetical protein 0.0039 0.0085 0.0081
Schistosoma mansoni nAChR subunit 0.0018 0.0006 0.0011
Mycobacterium tuberculosis Probable nitrite reductase [NAD(P)H] large subunit [FAD flavoprotein] NirB 0.0971 0.3593 0.8979
Schistosoma mansoni opsin-like receptor 0.0034 0.0067 0.0132
Echinococcus multilocularis uncharacterized sodium dependent transporter 0.0081 0.0241 0.0937
Loa Loa (eye worm) hypothetical protein 0.0039 0.0085 0.0081
Schistosoma mansoni hypothetical protein 0.0021 0.0017 0.0034
Leishmania major hypothetical protein, conserved 0.0034 0.0066 0.0061
Loa Loa (eye worm) hypothetical protein 0.0052 0.0134 0.0129
Echinococcus granulosus dro:myosuppressin receptor 0.0034 0.0067 0.0243
Schistosoma mansoni nAChR subunit 0.0039 0.0085 0.0169
Echinococcus granulosus neuropeptide receptor 0.0034 0.0067 0.0243
Brugia malayi nicotinic acetylcholine receptor beta-1 chain precursor 0.0039 0.0085 0.0085
Echinococcus multilocularis nicotinic acetylcholine receptor alpha subunit 0.0039 0.0085 0.0328
Mycobacterium ulcerans NADPH:adrenodoxin oxidoreductase FprB 0.0039 0.0085 0.0454
Brugia malayi nuclear receptor RXR 0.0048 0.0117 0.0117
Loa Loa (eye worm) aldehyde dehydrogenase 0.0027 0.0039 0.0034
Schistosoma mansoni ancient conserved domain protein 2 (cyclin m2) 0.0034 0.0067 0.0132
Schistosoma mansoni neuropeptide receptor 0.0034 0.0067 0.0132
Trichomonas vaginalis DNA helicase recq, putative 0.0021 0.0015 0.0055
Schistosoma mansoni peptide (FMRFamide/somatostatin)-like receptor 0.0034 0.0067 0.0132
Schistosoma mansoni hypothetical protein 0.0034 0.0067 0.0132
Echinococcus granulosus neuronal acetylcholine receptor subunit alpha 4 0.0039 0.0085 0.0312
Leishmania major aldehyde dehydrogenase, putative 0.0027 0.0039 0.0034
Mycobacterium ulcerans hypothetical protein 0.0039 0.0085 0.0454
Echinococcus granulosus hypothetical protein 0.0732 0.269 1
Entamoeba histolytica hypothetical protein 0.0019 0.0009 0.0046
Mycobacterium leprae conserved hypothetical protein 0.0023 0.0025 0.005
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0034 0.0067 0.0132
Schistosoma mansoni acetyl-CoA C-acetyltransferase 0.0031 0.0056 0.0111
Schistosoma mansoni myst-related protein 0.0019 0.0009 0.0018
Schistosoma mansoni serine/threonine protein kinase 0.0471 0.1711 0.339
Brugia malayi Acetylcholine receptor protein, alpha-like chain 1 precursor 0.0018 0.0006 0.0006
Loa Loa (eye worm) hypothetical protein 0.0074 0.0218 0.0213
Echinococcus multilocularis g protein coupled receptor 0.0034 0.0067 0.0255
Schistosoma mansoni aldehyde dehydrogenase 0.0027 0.0039 0.0076
Brugia malayi nuclear receptor RXR 0.0053 0.0139 0.0139
Schistosoma mansoni aldehyde dehydrogenase 0.0027 0.0039 0.0076
Brugia malayi Hypothetical glycine receptor like protein T20B12.9 in chromosome III 0.0021 0.0017 0.0017
Onchocerca volvulus 0.0033 0.0061 0.0237
Echinococcus multilocularis FAD linked sulfhydryl oxidase ALR 0.0034 0.0066 0.0251
Echinococcus multilocularis histone lysine N methyltransferase MLL3 0.0048 0.0118 0.0456
Loa Loa (eye worm) hypothetical protein 0.0034 0.0067 0.0062
Onchocerca volvulus 0.0039 0.0084 0.0328
Loa Loa (eye worm) nuclear hormone receptor 0.0048 0.0117 0.0113
Echinococcus granulosus bromodomain adjacent to zinc finger domain 0.0037 0.0077 0.028
Brugia malayi Succinate semialdehyde dehydrogenase, mitochondrial precursor 0.0027 0.0039 0.0039
Echinococcus granulosus rhodopsin orphan GPCR 0.0034 0.0067 0.0243
Loa Loa (eye worm) AGC/GRK/BARK protein kinase 0.0021 0.0015 0.001
Plasmodium falciparum dihydrolipoyl dehydrogenase, apicoplast 0.0148 0.0493 0.3195
Brugia malayi Cytochrome P450 family protein 0.0026 0.0037 0.0037
Entamoeba histolytica hypothetical protein 0.0019 0.0009 0.0045
Echinococcus multilocularis glycine receptor subunit alpha 1 0.0039 0.0085 0.0328
Trichomonas vaginalis CAMK family protein kinase 0.0233 0.0815 0.316
Mycobacterium ulcerans NADPH:adrenodoxin oxidoreductase FprA 0.0039 0.0085 0.0454
Loa Loa (eye worm) hypothetical protein 0.0021 0.0017 0.0012
Brugia malayi gamma-aminobutyric-acid receptor beta subunit precursor 0.0039 0.0085 0.0085
Plasmodium vivax FAD-linked sulfhydryl oxidase ERV1, putative 0.0034 0.0066 0.0418
Echinococcus multilocularis pyroglutamylated rfamide peptide receptor 0.0034 0.0067 0.0255
Trichomonas vaginalis conserved hypothetical protein 0.0033 0.0061 0.0231
Onchocerca volvulus 0.0034 0.0067 0.0258
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0033 0.0061 0.0233
Brugia malayi regulator of G-protein signaling egl-10 0.0019 0.0009 0.0009
Loa Loa (eye worm) ACC-1 protein 0.0039 0.0085 0.0081
Treponema pallidum sodium- and chloride- dependent transporter 0.0475 0.1726 1
Loa Loa (eye worm) hypothetical protein 0.0034 0.0067 0.0062
Schistosoma mansoni thyroid hormone receptor 0.0607 0.2223 0.4404
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0029 0.0045 0.0171
Giardia lamblia Glycerol-3-phosphate dehydrogenase 0.0039 0.0085 0.0277
Entamoeba histolytica cysteine proteinase, putative 0.0022 0.002 0.0112
Echinococcus multilocularis gamma aminobutyric acid receptor subunit 0.0018 0.0006 0.0017
Toxoplasma gondii methylmalonate-semialdehyde dehydrogenase [acylating], putative 0.0027 0.0039 0.0192
Echinococcus granulosus neuropeptide receptor 0.0034 0.0067 0.0243
Brugia malayi Sodium:neurotransmitter symporter family protein 0.0081 0.0241 0.0241
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0101 0.0318 0.0318
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0034 0.0067 0.0132
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0148 0.0493 0.0492
Brugia malayi G protein-coupled receptor F59B2.13 0.0034 0.0067 0.0067
Plasmodium vivax amine transporter, putative 0.0081 0.0241 0.1559
Loa Loa (eye worm) GABA receptor subunit 0.0021 0.0017 0.0012
Toxoplasma gondii histone lysine methyltransferase SET1 0.028 0.0989 0.557
Echinococcus granulosus thioredoxin glutathione reductase 0.0426 0.154 0.5721
Echinococcus multilocularis cathepsin L cysteine protease 0.0033 0.0061 0.0234
Echinococcus granulosus succinate semialdehyde dehydrogenase 0.0027 0.0039 0.0139
Schistosoma mansoni neurotransmitter gated ion channel 0.0021 0.0017 0.0034
Brugia malayi aminoadipate-semialdehyde dehydrogenase-phosphopantetheinyl transferase 0.0082 0.0247 0.0247
Trichomonas vaginalis conserved hypothetical protein 0.0033 0.0061 0.0231
Schistosoma mansoni dihydrolipoamide dehydrogenase 0.0148 0.0493 0.0976
Loa Loa (eye worm) hypothetical protein 0.0034 0.0067 0.0062
Loa Loa (eye worm) hypothetical protein 0.0034 0.0067 0.0062
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0034 0.0067 0.0132
Echinococcus granulosus geminin 0.05 0.1819 0.676
Loa Loa (eye worm) hypothetical protein 0.0081 0.0241 0.0237
Onchocerca volvulus Serine\/threonine kinase homolog 0.0471 0.1711 0.6636
Echinococcus granulosus sodium and chloride dependent glycine 0.0081 0.0241 0.0892
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0033 0.0061 0.0233
Echinococcus multilocularis cpg binding protein 0.0155 0.052 0.2026
Brugia malayi PXA domain containing protein 0.0019 0.0009 0.0009
Echinococcus multilocularis L aminoadipate semialdehyde 0.0082 0.0247 0.0961
Trypanosoma cruzi cysteine peptidase, clan CA, family C1, cathepsin L-like, putative 0.0114 0.0368 0.0367
Leishmania major cathepsin L-like protease 0.0125 0.0409 0.0404
Loa Loa (eye worm) CXXC zinc finger family protein 0.0145 0.0481 0.0477
Echinococcus multilocularis acetylcholine receptor subunit beta 1 0.0039 0.0085 0.0328
Loa Loa (eye worm) cytochrome P450 family protein 0.0026 0.0037 0.0033
Loa Loa (eye worm) hypothetical protein 0.0034 0.0067 0.0062
Echinococcus multilocularis neuropeptide s receptor 0.0034 0.0067 0.0255
Loa Loa (eye worm) hypothetical protein 0.0033 0.0061 0.0057
Onchocerca volvulus 0.0039 0.0085 0.033
Leishmania major pyrroline-5-carboxylate synthetase-like protein 0.0027 0.0039 0.0034
Leishmania major cathepsin L-like protease 0.0033 0.0061 0.0057
Echinococcus granulosus A kinase anchor protein 10 mitochondrial 0.0019 0.0009 0.0029
Brugia malayi Cytochrome P450 family protein 0.0018 0.0005 0.0005
Brugia malayi MH2 domain containing protein 0.0118 0.0383 0.0383
Trypanosoma cruzi cysteine peptidase, putative 0.0033 0.0061 0.006
Brugia malayi PHD-finger family protein 0.0034 0.0065 0.0065
Schistosoma mansoni regulator of G protein signaling 3 rgs3 0.0019 0.0009 0.0018
Loa Loa (eye worm) hypothetical protein 0.0101 0.0318 0.0314
Echinococcus multilocularis regulator of G protein signaling 3 0.0019 0.0009 0.003
Echinococcus granulosus chromodomain helicase DNA binding protein 4 0.0021 0.0018 0.0061
Echinococcus multilocularis rhodopsin orphan GPCR 0.0034 0.0067 0.0255
Loa Loa (eye worm) acetylcholine receptor protein 0.0018 0.0006 0.0001
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0125 0.0409 0.0408
Loa Loa (eye worm) hypothetical protein 0.0048 0.0117 0.0113
Schistosoma mansoni growth hormone secretagogue receptor 0.0034 0.0067 0.0132
Echinococcus granulosus bloom syndrome protein 0.0021 0.0015 0.0053
Leishmania major aldehyde dehydrogenase, putative 0.0027 0.0039 0.0034
Echinococcus multilocularis fetal alzheimer antigen, falz 0.0031 0.0056 0.0213
Wolbachia endosymbiont of Brugia malayi thioredoxin reductase 0.0039 0.0085 0.1287
Schistosoma mansoni SmCL2-like peptidase (C01 family) 0.0017 0.0001 0.0002
Brugia malayi nicotinic acetylcholine receptor alpha subunit, putative 0.0039 0.0085 0.0085
Mycobacterium ulcerans bifunctional acetaldehyde-CoA/alcohol dehydrogenase 0.0027 0.0039 0.0192
Loa Loa (eye worm) hypothetical protein 0.0018 0.0006 0.0001
Onchocerca volvulus Dopamine\/Ecdysteroid receptor homolog 0.0034 0.0067 0.0258
Brugia malayi hypothetical protein 0.0034 0.0067 0.0067
Mycobacterium ulcerans NADPH dependent 2,4-dienoyl-CoA reductase FadH 0.0039 0.0085 0.0454
Echinococcus granulosus L aminoadipate semialdehyde 0.0082 0.0247 0.0915
Loa Loa (eye worm) glutamate-gated chloride channel alpha3A subunit 0.0018 0.0006 0.0001
Toxoplasma gondii selenide, water dikinase 0.0039 0.0085 0.0454
Leishmania major 2,4-dienoyl-coa reductase fadh1, putative 0.0039 0.0085 0.008
Toxoplasma gondii cathepsin CPL 0.0033 0.0061 0.032
Brugia malayi Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain containing protein 0.0108 0.0345 0.0345
Echinococcus granulosus cytoplasmic intermediate filament protein 0.004 0.0087 0.032
Onchocerca volvulus Cathepsin F homolog 0.0033 0.0061 0.0237
Echinococcus multilocularis nuclear receptor subfamily 4 group A 0.0048 0.0117 0.0452
Echinococcus granulosus glycine receptor subunit alpha 1 0.0039 0.0085 0.0312
Brugia malayi nuclear receptor subfamily 1, group D, member 1, putative 0.0048 0.0117 0.0117
Echinococcus granulosus regulator of G protein signaling 3 0.0019 0.0009 0.0029
Brugia malayi Nuclear hormone receptor family member nhr-40 0.0101 0.0318 0.0318
Schistosoma mansoni transcription factor LCR-F1 0.0035 0.0068 0.0135
Echinococcus granulosus G protein coupled receptor 139 0.0034 0.0067 0.0243
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0033 0.0061 0.0233
Brugia malayi A-kinase anchor protein 10, precursor 0.0019 0.0009 0.0009
Loa Loa (eye worm) delta-1-pyrroline-5-carboxylate dehydrogenase 0.0027 0.0039 0.0034
Onchocerca volvulus 0.0048 0.0117 0.0454
Leishmania major dihydrolipoamide dehydrogenase, putative 0.0148 0.0493 0.0488
Loa Loa (eye worm) hypothetical protein 0.0286 0.1013 0.1009
Echinococcus granulosus neuropeptides capa receptor 0.0034 0.0067 0.0243
Echinococcus granulosus bromodomain adjacent to zinc finger domain 0.007 0.02 0.0738
Brugia malayi gonadotropin-releasing hormone receptor 2 0.0034 0.0067 0.0067
Loa Loa (eye worm) nuclear hormone receptor family member nhr-40 0.0101 0.0318 0.0314
Schistosoma mansoni nAChR subunit (ShAR1-beta2-like) 0.0039 0.0085 0.0169
Trichomonas vaginalis disulfide oxidoreductase, putative 0.0039 0.0085 0.0325
Echinococcus multilocularis histone lysine N methyltransferase MLL3 0.0039 0.0085 0.0327
Onchocerca volvulus 0.0034 0.0067 0.0258
Schistosoma mansoni nAChR subunit 0.0039 0.0085 0.0169
Loa Loa (eye worm) norepinephrine transporter 0.0475 0.1726 0.1722
Wolbachia endosymbiont of Brugia malayi thioredoxin reductase 0.0039 0.0085 0.1287
Echinococcus multilocularis rhodopsin orphan GPCR 0.0034 0.0067 0.0255
Mycobacterium tuberculosis holo-[acyl-carrier protein] synthase AcpS (holo-ACP synthase) (CoA:APO-[ACP]pantetheinephosphotransferase) (CoA:APO-[acyl-carrie 0.0023 0.0025 0.005
Echinococcus granulosus neuropeptide Y receptor 0.0034 0.0067 0.0243
Loa Loa (eye worm) hypothetical protein 0.0034 0.0067 0.0062
Loa Loa (eye worm) nuclear hormone receptor family member nhr-41 0.0101 0.0318 0.0314
Mycobacterium tuberculosis Probable short-chain type dehydrogenase/reductase 0.0061 0.0165 0.0402
Schistosoma mansoni amine GPCR 0.0034 0.0067 0.0132
Loa Loa (eye worm) melatonin receptor type 1A 0.0034 0.0067 0.0062
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0033 0.0061 0.0233
Loa Loa (eye worm) hypothetical protein 0.0018 0.0006 0.0001
Echinococcus granulosus regulator of G protein signaling 3 0.0019 0.0009 0.0029
Brugia malayi Unidentified vitellogenin-linked transcript protein 6, putative 0.0034 0.0067 0.0067
Trypanosoma cruzi cysteine peptidase, putative 0.0125 0.0409 0.0408
Echinococcus granulosus NADPH:adrenodoxin oxidoreductase 0.0039 0.0085 0.0311
Loa Loa (eye worm) G-protein coupled receptor 0.0034 0.0067 0.0062
Loa Loa (eye worm) hypothetical protein 0.0053 0.0139 0.0134
Echinococcus granulosus regulator of G protein signaling 7 0.0019 0.0009 0.0029
Loa Loa (eye worm) neuropeptide F receptor 0.0034 0.0067 0.0062
Wolbachia endosymbiont of Brugia malayi bifunctional proline dehydrogenase/pyrroline-5-carboxylate dehydrogenase 0.0027 0.0039 0.0296
Brugia malayi Neurotransmitter-gated ion-channel ligand binding domain containing protein 0.0039 0.0085 0.0085
Brugia malayi Doublecortin family protein 0.0039 0.0084 0.0084
Onchocerca volvulus 0.0145 0.0481 0.1867
Echinococcus multilocularis biogenic amine (5HT) receptor 0.0034 0.0067 0.0255
Onchocerca volvulus 0.0098 0.0307 0.1193
Echinococcus granulosus nAChR subunit 0.0039 0.0085 0.0312
Brugia malayi Cathepsin L-like precursor 0.0033 0.0061 0.0061
Loa Loa (eye worm) hypothetical protein 0.0081 0.0242 0.0238
Echinococcus multilocularis glutamate synthase 0.0039 0.0085 0.0327
Leishmania major hypothetical protein, conserved 0.0039 0.0085 0.008
Loa Loa (eye worm) hypothetical protein 0.0018 0.0006 0.0001
Brugia malayi Nuclear hormone receptor E75 0.0048 0.0117 0.0117
Toxoplasma gondii 4'-phosphopantetheinyl transferase domain-containing protein 0.0023 0.0025 0.0114
Trichomonas vaginalis conserved hypothetical protein 0.0019 0.0009 0.003
Echinococcus multilocularis nicotinic acetylcholine receptor subunit type 0.0018 0.0006 0.0017
Brugia malayi Neurotransmitter-gated ion-channel ligand binding domain containing protein 0.0018 0.0006 0.0006
Loa Loa (eye worm) hypothetical protein 0.0034 0.0067 0.0062
Plasmodium vivax vivapain-2 0.0033 0.0061 0.039
Schistosoma mansoni aldehyde dehydrogenase 0.0027 0.0039 0.0076
Echinococcus multilocularis neuropeptide receptor A26 0.0034 0.0067 0.0255
Toxoplasma gondii 4'-phosphopantetheinyl transferase superfamily protein 0.0023 0.0025 0.0114
Trypanosoma brucei aldehyde dehydrogenase, putative 0.0027 0.0039 0.0037
Brugia malayi hypothetical protein 0.0018 0.0006 0.0006
Echinococcus multilocularis glycine receptor subunit beta 0.0039 0.0085 0.0328
Brugia malayi Neurotransmitter-gated ion-channel ligand binding domain containing protein 0.0039 0.0085 0.0085
Schistosoma mansoni 3-hydroxyacyl-CoA dehydrogenase 0.0061 0.0165 0.0328
Loa Loa (eye worm) hypothetical protein 0.0019 0.0009 0.0004
Loa Loa (eye worm) hypothetical protein 0.2674 1 1
Trypanosoma brucei ERV/ALR sulfhydryl oxidase domain-containing protein 0.0034 0.0066 0.0064
Schistosoma mansoni sodium/chloride dependent transporter 0.0475 0.1726 0.3419
Entamoeba histolytica cysteine proteinase, putative 0.0033 0.0061 0.0351
Loa Loa (eye worm) hypothetical protein 0.0039 0.0085 0.0081
Echinococcus multilocularis neuropeptide FF receptor 2 0.0034 0.0067 0.0255
Brugia malayi Cathepsin L-like cysteine proteinase 0.0022 0.002 0.002
Loa Loa (eye worm) gonadotropin-releasing hormone receptor 2 0.0034 0.0067 0.0062
Brugia malayi Neurotransmitter-gated ion-channel ligand binding domain containing protein 0.0039 0.0085 0.0085
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0125 0.0409 0.0408
Trypanosoma cruzi pyridine nucleotide-disulphide oxidoreductase, putative 0.0039 0.0085 0.0084
Brugia malayi dihydrolipoyl dehydrogenase, mitochondrial precursor, putative 0.0148 0.0493 0.0493
Loa Loa (eye worm) hypothetical protein 0.0039 0.0085 0.0081
Loa Loa (eye worm) hypothetical protein 0.0039 0.0085 0.0081
Brugia malayi hypothetical protein 0.0053 0.0139 0.0139
Echinococcus multilocularis Nuclear hormone receptor HR96 0.0048 0.0117 0.0452
Echinococcus multilocularis Cys loop ligand gated ion channel subunit 0.0018 0.0006 0.0017
Echinococcus granulosus Regulator of G protein signaling 20 0.0019 0.0009 0.0029
Leishmania major aldehyde dehydrogenase, mitochondrial precursor 0.0488 0.1773 0.1769
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0148 0.0493 0.0492
Loa Loa (eye worm) nuclear hormone receptor family member nhr-1 0.0101 0.0318 0.0314
Mycobacterium leprae PROBABLE SUCCINATE-SEMIALDEHYDE DEHYDROGENASE [NADP+] DEPENDENT (SSDH) GABD 0.0027 0.0039 0.0085
Trypanosoma cruzi NADH dehydrogenase, putative 0.0039 0.0085 0.0084
Loa Loa (eye worm) hypothetical protein 0.0039 0.0086 0.0082
Trypanosoma cruzi pyrroline-5-carboxylate synthetase-like protein, putative 0.0027 0.0039 0.0037
Loa Loa (eye worm) hepatopoietin HPO2 0.0034 0.0066 0.0061
Schistosoma mansoni nuclear receptor nhr-48 0.0048 0.0117 0.0232
Trypanosoma cruzi cytochrome P450, putative 0.0026 0.0037 0.0036
Echinococcus granulosus 7TM GPCR rhodopsin 0.0034 0.0067 0.0243
Echinococcus granulosus Nuclear hormone receptor HR96 0.0048 0.0117 0.0431
Echinococcus multilocularis conserved hypothetical protein 0.0697 0.2561 1
Onchocerca volvulus 0.0102 0.0322 0.125
Loa Loa (eye worm) nuclear receptor NHR-67 0.0048 0.0117 0.0113
Echinococcus granulosus tm gpcr rhodopsin 0.0034 0.0067 0.0243
Echinococcus multilocularis sodium:chloride dependent neurotransmitter 0.0081 0.0241 0.0937
Plasmodium vivax ferrodoxin reductase, putative 0.0039 0.0085 0.0544
Loa Loa (eye worm) hypothetical protein 0.0039 0.0085 0.0081
Echinococcus granulosus dihydrolipoamide dehydrogenase 0.0148 0.0493 0.1828
Mycobacterium leprae THIOREDOXIN TRXC (TRX) (MPT46) 0.0039 0.0085 0.0201
Loa Loa (eye worm) hypothetical protein 0.0034 0.0067 0.0062
Brugia malayi Steroid receptor seven-up type 2 0.0101 0.0318 0.0318
Mycobacterium ulcerans monoxygenase 0.0039 0.0085 0.0454
Leishmania major cytochrome p450-like protein 0.0026 0.0037 0.0033
Loa Loa (eye worm) hypothetical protein 0.0018 0.0006 0.0001
Trypanosoma brucei hypothetical protein, conserved 0.0023 0.0025 0.0023
Entamoeba histolytica hypothetical protein 0.0019 0.0009 0.0045
Loa Loa (eye worm) hypothetical protein 0.0081 0.0241 0.0237
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0033 0.0061 0.0233
Schistosoma mansoni amine GPCR 0.0034 0.0067 0.0132
Schistosoma mansoni hypothetical protein 0.0034 0.0067 0.0132
Schistosoma mansoni peptide (allatostatin/somatostatin)-like receptor 0.0034 0.0067 0.0132
Echinococcus multilocularis axis inhibition protein axin 0.0019 0.0009 0.003
Loa Loa (eye worm) hypothetical protein 0.1367 0.5081 0.5078
Trichomonas vaginalis glutamate synthase, putative 0.0039 0.0085 0.0325
Schistosoma mansoni aldehyde dehydrogenase 0.0488 0.1773 0.3512
Schistosoma mansoni ecdysone-induced protein 78c (dr-78) 0.0053 0.0139 0.0275
Echinococcus granulosus g protein linked acetylcholine receptor gar 2a 0.0034 0.0067 0.0243
Schistosoma mansoni nuclear hormone receptor 0.0101 0.0318 0.063
Schistosoma mansoni acetylcholine receptor-related 0.0018 0.0006 0.0011
Trichomonas vaginalis Clan CA, family C1, cathepsin L or K-like cysteine peptidase 0.0033 0.0061 0.0233
Echinococcus multilocularis lamin 0.0082 0.0248 0.0964
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0039 0.0085 0.0168
Echinococcus multilocularis nicotinic acetylcholine receptor subunit alpha 8 0.0039 0.0085 0.0328
Echinococcus granulosus regulator of G protein signaling 7 0.0019 0.0009 0.0029
Onchocerca volvulus Protein ultraspiracle homolog 0.0101 0.0318 0.1234
Onchocerca volvulus 0.0033 0.0061 0.0237
Schistosoma mansoni amine GPCR 0.0034 0.0067 0.0132
Loa Loa (eye worm) hypothetical protein 0.0021 0.0017 0.0012
Leishmania major 2,4-dienoyl-coa reductase-like protein 0.0039 0.0085 0.008
Echinococcus granulosus glycine receptor subunit alpha 1 0.0039 0.0085 0.0312
Brugia malayi Neurotransmitter-gated ion-channel ligand binding domain containing protein 0.0018 0.0006 0.0006
Mycobacterium ulcerans NADH dehydrogenase 0.0039 0.0085 0.0454
Schistosoma mansoni nAChR subunit (ShAR1-beta-like) 0.0039 0.0085 0.0169
Brugia malayi Cathepsin L-like precursor 0.0033 0.0061 0.0061
Echinococcus multilocularis histone lysine N methyltransferase SETMAR 0.0091 0.0281 0.1092
Echinococcus granulosus acetylcholine receptor subunit beta 1 0.0039 0.0085 0.0312
Mycobacterium leprae Probable NADPH:adrenodoxin oxidoreductase FprA (NADPH-FERREDOXIN REDUCTASE) 0.0039 0.0085 0.0201
Loa Loa (eye worm) hypothetical protein 0.0475 0.1726 0.1722
Mycobacterium leprae PROBABLE ENDONUCLEASE IV END (ENDODEOXYRIBONUCLEASE IV) (APURINASE) 0.0074 0.0218 0.0533
Trypanosoma cruzi aldehyde dehydrogenase family, putative 0.0027 0.0039 0.0037
Schistosoma mansoni cathepsin F (C01 family) 0.0022 0.002 0.004
Loa Loa (eye worm) hypothetical protein 0.0039 0.0085 0.0081
Mycobacterium leprae conserved hypothetical protein 0.002 0.0011 0.0017
Schistosoma mansoni lamin 0.0082 0.0248 0.0491
Loa Loa (eye worm) acetylcholine receptor alpha subunit 0.0039 0.0085 0.0081
Echinococcus granulosus ecdysone induced protein 78C 0.0101 0.0318 0.1178
Echinococcus granulosus G protein coupled 5 hydroxytryptamine receptor 0.0034 0.0067 0.0243
Echinococcus granulosus somatostatin receptor 0.0034 0.0067 0.0243
Echinococcus granulosus sex peptide receptor 0.0034 0.0067 0.0243
Schistosoma mansoni zinc finger protein 0.0028 0.0044 0.0088
Echinococcus granulosus Polycystic kidney disease protein 0.0039 0.0084 0.0309
Brugia malayi putative neuropeptide receptor NPR1 0.0034 0.0067 0.0067
Trichomonas vaginalis DNA helicase recq1, putative 0.0021 0.0015 0.0055
Onchocerca volvulus 0.0034 0.0067 0.0258
Loa Loa (eye worm) hypothetical protein 0.0048 0.0117 0.0113
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0148 0.0493 0.0492
Loa Loa (eye worm) G-protein coupled receptor 0.0034 0.0067 0.0062
Brugia malayi Cathepsin L-like precursor 0.0033 0.0061 0.0061
Trichomonas vaginalis helicase, putative 0.0033 0.0061 0.0231
Trypanosoma cruzi aldehyde dehydrogenase, putative 0.0027 0.0039 0.0037
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0033 0.0061 0.0233
Echinococcus granulosus Basic leucine zipper bZIP transcription 0.0035 0.0068 0.0249
Loa Loa (eye worm) PXA domain-containing protein 0.0019 0.0009 0.0004
Brugia malayi M-phase phosphoprotein, mpp8 0.0098 0.0307 0.0307
Plasmodium falciparum zinc finger protein, putative 0.0019 0.0009 0.0051
Loa Loa (eye worm) hypothetical protein 0.0022 0.002 0.0016
Loa Loa (eye worm) hypothetical protein 0.0021 0.0017 0.0012
Loa Loa (eye worm) RGS-3 protein 0.0019 0.0009 0.0004
Echinococcus granulosus nicotinic acetylcholine receptor subunit alpha 8 0.0039 0.0085 0.0312
Schistosoma mansoni neurotransmitter gated ion channel 0.0018 0.0006 0.0011
Echinococcus granulosus hepatocyte nuclear factor 4 alpha 0.0101 0.0318 0.1178
Brugia malayi tailless protein 0.0048 0.0117 0.0117
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0024 0.0028 0.0055
Brugia malayi GnHR receptor homolog 0.0034 0.0067 0.0067
Brugia malayi hypothetical protein 0.0034 0.0067 0.0067
Echinococcus multilocularis chromodomain helicase DNA binding protein 4 0.0021 0.0018 0.0064
Schistosoma mansoni regulator of G protein signaling 0.0019 0.0009 0.0018
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0101 0.0318 0.1178
Schistosoma mansoni bromodomain containing protein 0.0073 0.0213 0.0423
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0044 0.0102 0.0393
Mycobacterium tuberculosis Probable aldehyde dehydrogenase (NAD+) dependent 0.0027 0.0039 0.0085
Brugia malayi hypothetical protein 0.0019 0.0009 0.0009
Echinococcus multilocularis dro:myosuppressin receptor 0.0034 0.0067 0.0255
Echinococcus granulosus g-protein coupled receptor 0.0034 0.0067 0.0243
Echinococcus granulosus betaine aldehyde dehydrogenase 0.0027 0.0039 0.0139
Loa Loa (eye worm) hypothetical protein 0.0019 0.0009 0.0004
Schistosoma mansoni RAR-like nuclear receptor 0.0101 0.0318 0.063
Loa Loa (eye worm) serotonin transporter b 0.0475 0.1726 0.1722
Trypanosoma brucei cytochrome P450, putative 0.0026 0.0037 0.0036
Schistosoma mansoni hypothetical protein 0.0039 0.0084 0.0167
Schistosoma mansoni biogenic amine receptor 0.0034 0.0067 0.0132
Loa Loa (eye worm) hypothetical protein 0.0034 0.0067 0.0062
Loa Loa (eye worm) transcription factor SMAD2 0.0118 0.0383 0.0379
Trypanosoma brucei NADH dehydrogenase 0.0039 0.0085 0.0084
Brugia malayi nuclear hormone receptor 0.0101 0.0318 0.0318
Brugia malayi nuclear hormone receptor family member nhr-6 0.0048 0.0117 0.0117
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0034 0.0067 0.0255
Onchocerca volvulus 0.0034 0.0067 0.0258
Echinococcus granulosus zinc finger protein 0.0028 0.0044 0.016
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0034 0.0067 0.0132
Echinococcus multilocularis neuropeptide receptor 0.0034 0.0067 0.0255
Echinococcus granulosus serotonin receptor 0.0034 0.0067 0.0243
Brugia malayi hypothetical protein 0.0034 0.0067 0.0067
Loa Loa (eye worm) nuclear Hormone Receptor family member 0.0101 0.0318 0.0314
Schistosoma mansoni neurotransmitter gated ion channel 0.0018 0.0006 0.0011
Echinococcus multilocularis musashi 0.0082 0.0248 0.0964
Loa Loa (eye worm) hypothetical protein 0.0019 0.0009 0.0004
Chlamydia trachomatis Ssodium-dependent amino acid transporter 0.0081 0.0241 0.4624
Echinococcus granulosus FTZ F1 alpha 0.0101 0.0318 0.1178
Mycobacterium tuberculosis Probable aldehyde dehydrogenase AldC 0.0027 0.0039 0.0085
Schistosoma mansoni sodium-dependent neurotransmitter transporter 0.0081 0.0241 0.0478
Echinococcus granulosus rhodopsin orphan GPCR 0.0034 0.0067 0.0243
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0034 0.0067 0.0132
Plasmodium falciparum ADP-dependent DNA helicase RecQ 0.0018 0.0006 0.0031
Echinococcus granulosus biogenic amine 5HT receptor 0.0286 0.1013 0.3762
Mycobacterium tuberculosis Probable NADPH dependent 2,4-dienoyl-CoA reductase FadH (2,4-dienoyl coenzyme A reductase) (4-enoyl-CoA reductase) 0.0039 0.0085 0.0201
Loa Loa (eye worm) Papain cysteine protease/cathepsin propeptide inhibitor-containing protein 0.0033 0.0061 0.0057
Schistosoma mansoni nAChR subunit (ShAR1-alpha-like) 0.0039 0.0085 0.0169
Echinococcus granulosus Cys loop ligand gated ion channel subunit 0.0039 0.0085 0.0312
Onchocerca volvulus 0.0034 0.0067 0.0258
Leishmania major cysteine peptidase A (CPA) 0.0033 0.0061 0.0057
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0033 0.0061 0.0233
Schistosoma mansoni nuclear receptor 0.0048 0.0117 0.0232
Trypanosoma cruzi dihydrolipoyl dehydrogenase, putative 0.0148 0.0493 0.0492
Brugia malayi Cathepsin L-like precursor 0.0022 0.002 0.002
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0044 0.0102 0.0393
Loa Loa (eye worm) hypothetical protein 0.0021 0.0017 0.0012
Mycobacterium ulcerans NADH dehydrogenase Ndh1 0.0039 0.0085 0.0454
Loa Loa (eye worm) hypothetical protein 0.0019 0.0009 0.0004
Echinococcus granulosus glycine receptor subunit beta 0.0039 0.0085 0.0312
Brugia malayi hypothetical protein 0.0034 0.0067 0.0067
Loa Loa (eye worm) hypothetical protein 0.0082 0.0248 0.0243
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0034 0.0067 0.0132
Schistosoma mansoni lipoxygenase 0.0101 0.0318 0.063
Echinococcus granulosus aldehyde dehydrogenase mitochondrial 0.0488 0.1773 0.6587
Trichomonas vaginalis CAMK family protein kinase 0.0471 0.1711 0.6635
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0022 0.002 0.0074
Echinococcus multilocularis Fatty aldehyde dehydrogenase 0.0027 0.0039 0.0146
Echinococcus granulosus neuropeptide receptor A26 0.0034 0.0067 0.0243
Loa Loa (eye worm) hypothetical protein 0.0034 0.0067 0.0062
Brugia malayi Pre-SET motif family protein 0.0091 0.0281 0.0281
Echinococcus granulosus fmrfamide receptor 0.0034 0.0067 0.0243
Onchocerca volvulus Neuropeptide F receptor homolog 0.0034 0.0067 0.0258
Leishmania major cathepsin L-like protease 0.0033 0.0061 0.0057
Echinococcus granulosus FAD linked sulfhydryl oxidase ALR 0.0034 0.0066 0.0239
Echinococcus multilocularis regulator of G protein signaling 0.0019 0.0009 0.003
Mycobacterium ulcerans aldehyde dehydrogenase 0.0488 0.1773 1
Plasmodium falciparum thioredoxin reductase 0.0148 0.0493 0.3195
Mycobacterium ulcerans methylmalonate semialdehyde dehydrogenase, MmsA 0.0027 0.0039 0.0192
Trichomonas vaginalis conserved hypothetical protein 0.0019 0.0009 0.003
Loa Loa (eye worm) hypothetical protein 0.0039 0.0085 0.0081
Brugia malayi Neurotransmitter-gated ion-channel transmembrane region family protein 0.0039 0.0085 0.0085
Mycobacterium tuberculosis NAD(P)H quinone reductase LpdA 0.108 0.4 1
Brugia malayi Sodium:neurotransmitter symporter family protein 0.0081 0.0241 0.0241
Loa Loa (eye worm) cytoplasmic intermediate filament protein 0.0044 0.0104 0.0099
Trypanosoma brucei Lanosterol 14-alpha demethylase 0.0018 0.0005 0.0003
Trypanosoma cruzi cruzipain precursor, putative 0.0125 0.0409 0.0408
Plasmodium falciparum amino acid transporter, putative 0.0081 0.0241 0.1559
Echinococcus multilocularis cysteine protease 0.0033 0.0061 0.0234
Schistosoma mansoni nuclear hormone receptor superfamily protein-related 0.0048 0.0117 0.0232
Echinococcus multilocularis g protein coupled receptor 0.0034 0.0067 0.0255
Schistosoma mansoni regulator of G protein signaling 17 19 20 (rgs17 19 20) 0.0019 0.0009 0.0018
Echinococcus multilocularis fmrfamide receptor 0.0034 0.0067 0.0255
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0033 0.0061 0.0233
Schistosoma mansoni biogenic amine (octopamine/dopamine) receptor 0.033 0.1179 0.2335
Trypanosoma cruzi trypanothione reductase, putative 0.0148 0.0493 0.0492
Brugia malayi Neurotransmitter-gated ion-channel ligand binding domain containing protein 0.0018 0.0006 0.0006
Brugia malayi Hypothetical 29.7 kDa protein C05D11.5 in chromosome III 0.002 0.0011 0.0011
Echinococcus granulosus histone lysine N methyltransferase MLL3 0.0048 0.0118 0.0434
Brugia malayi Cathepsin L-like precursor 0.0033 0.0061 0.0061
Echinococcus multilocularis peptide (allatostatin:somatostatin) 0.0034 0.0067 0.0255
Trichomonas vaginalis conserved hypothetical protein 0.0033 0.0061 0.0231
Echinococcus granulosus neuropeptide Y receptor 0.0034 0.0067 0.0243
Echinococcus granulosus tm gpcr rhodopsin 0.0034 0.0067 0.0243
Leishmania major cathepsin L-like protease 0.0033 0.0061 0.0057
Echinococcus multilocularis cysteine protease 0.0033 0.0061 0.0234
Brugia malayi Neurotransmitter-gated ion-channel transmembrane region family protein 0.0039 0.0085 0.0085
Entamoeba histolytica cysteine protease, putative 0.0033 0.0061 0.0351
Echinococcus multilocularis growth hormone secretagogue receptor type 1 0.0034 0.0067 0.0255
Loa Loa (eye worm) TYRA-2 protein 0.0034 0.0067 0.0062

Activities

Activity type Activity value Assay description Source Reference
Effect (functional) = 15 % Compound is measured for oral antihypertensive activity in groups of 6-12 conscious spontaneously hypertensive rats at 1 mg/kg; Range is 15-20% ChEMBL. 7452693
Effect (functional) > 20 % Compound is measured for oral antihypertensive activity in groups of 6-12 deoxy-corticosterone-sodium hypertensive (DOCA-Na) rats at 10 mg/kg(fall in systolic blood pressure 6-24 h after dosing) ChEMBL. 7452693
Effect (functional) > 20 % Compound is measured for oral antihypertensive activity in groups of 6-12 conscious spontaneously hypertensive rats at 10 mg/kg(fall in systolic blood pressure 6-24 h after dosing) ChEMBL. 7452693

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
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External resources for this compound

Bibliographic References

1 literature reference was collected for this gene.

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