Detailed information for compound 405824

Basic information

Technical information
  • Name: Unnamed compound
  • MW: 2539.08 | Formula: C122H180N34O22S2
  • H donors: 34 H acceptors: 22 LogP: 3.56 Rotable bonds: 95
    Rule of 5 violations (Lipinski): 4
  • SMILES: CCC[C@@H](C(=O)N[C@H](C(=O)N[C@H](C(=O)N)Cc1ccc(cc1)O)CCCN=C(N)N)NC(=O)[C@@H](NC(=O)[C@H](Cc1c[nH]c2c1cccc2)NC(=O)[C@@H](NC(=O)[C@@H](NC(=O)[C@H]([C@H](CC)C)NC(=O)[C@H](Cc1ccc(cc1)O)N)CC(C)C)CSSC[C@@H](C(=O)N[C@H](C(=O)N[C@H](C(=O)N[C@H](C(=O)N[C@H](C(=O)N[C@H](C(=O)N)Cc1ccc(cc1)O)CCCN=C(N)N)CCC)CCCN=C(N)N)Cc1c[nH]c2c1cccc2)NC(=O)[C@@H](NC(=O)[C@H]([C@H](CC)C)NC(=O)[C@H](Cc1ccc(cc1)O)N)CC(C)C)CCCN=C(N)N
  • InChi: 1S/C122H180N34O22S2/c1-11-23-85(105(165)143-89(31-21-51-137-121(131)132)109(169)147-91(101(125)161)57-71-37-45-77(159)46-38-71)141-107(167)87(29-19-49-135-119(127)128)145-113(173)95(59-73-61-139-83-27-17-15-25-79(73)83)149-115(175)97(153-111(171)93(53-65(5)6)151-117(177)99(67(9)13-3)155-103(163)81(123)55-69-33-41-75(157)42-34-69)63-179-180-64-98(154-112(172)94(54-66(7)8)152-118(178)100(68(10)14-4)156-104(164)82(124)56-70-35-43-76(158)44-36-70)116(176)150-96(60-74-62-140-84-28-18-16-26-80(74)84)114(174)146-88(30-20-50-136-120(129)130)108(168)142-86(24-12-2)106(166)144-90(32-22-52-138-122(133)134)110(170)148-92(102(126)162)58-72-39-47-78(160)48-40-72/h15-18,25-28,33-48,61-62,65-68,81-82,85-100,139-140,157-160H,11-14,19-24,29-32,49-60,63-64,123-124H2,1-10H3,(H2,125,161)(H2,126,162)(H,141,167)(H,142,168)(H,143,165)(H,144,166)(H,145,173)(H,146,174)(H,147,169)(H,148,170)(H,149,175)(H,150,176)(H,151,177)(H,152,178)(H,153,171)(H,154,172)(H,155,163)(H,156,164)(H4,127,128,135)(H4,129,130,136)(H4,131,132,137)(H4,133,134,138)/t67-,68-,81-,82-,85-,86-,87-,88-,89-,90-,91-,92-,93-,94-,95-,96-,97-,98-,99-,100-/m0/s1
  • InChiKey: SONUWJTZAPUENI-BGZCAATLSA-N  


Substructure search Similarity search

Network

Hover on a compound node to display the structore

Synonyms

No synonyms found for this compound

Targets

Known targets for this compound

Species Target name Source Bibliographic reference
Homo sapiens neuropeptide Y receptor Y2 Starlite/ChEMBL References
Homo sapiens neuropeptide Y receptor Y1 Starlite/ChEMBL References

Predicted pathogen targets for this compound

By orthology
Species Potential target Known druggable target/s Ortholog Group
Echinococcus multilocularis G protein coupled receptor 139 Get druggable targets OG5_127863 All targets in OG5_127863
Schistosoma japonicum ko:K04209 neuropeptide Y receptor, invertebrate, putative Get druggable targets OG5_127863 All targets in OG5_127863
Echinococcus granulosus neuropeptide receptor Get druggable targets OG5_127863 All targets in OG5_127863
Echinococcus multilocularis neuropeptide receptor Get druggable targets OG5_127863 All targets in OG5_127863
Schistosoma mansoni neuropeptide receptor Get druggable targets OG5_127863 All targets in OG5_127863
By sequence similarity to non orthologous known druggable targets
Species Potential target Known druggable target Length Alignment span Identity
Echinococcus granulosus pyroglutamylated rfamide peptide receptor neuropeptide Y receptor Y2 381 aa 388 aa 20.4 %
Brugia malayi follicle stimulating hormone receptor neuropeptide Y receptor Y1 384 aa 345 aa 22.0 %
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Brugia malayi Protein kinase domain containing protein 0.0027 0.0084 0.0239
Brugia malayi TAR-binding protein 0.0044 0.0159 0.0452
Loa Loa (eye worm) hypothetical protein 0.0008 0.0005 0.0014
Brugia malayi steroid hormone receptor 0.0156 0.0634 0.1804
Loa Loa (eye worm) hypothetical protein 0.0156 0.0634 0.1804
Loa Loa (eye worm) hypothetical protein 0.0045 0.0162 0.0461
Echinococcus granulosus Niemann Pick C1 protein 0.0069 0.0263 0.043
Echinococcus granulosus tyrosine protein kinase Src42A 0.0012 0.0021 0.0035
Echinococcus granulosus g protein coupled receptor 0.0031 0.0103 0.0168
Schistosoma mansoni kinase 0.0175 0.0717 0.1174
Plasmodium falciparum DNA topoisomerase VI, b subunit, putative 0.0009 0.0008 0.0025
Brugia malayi hypothetical protein 0.0031 0.0103 0.0292
Loa Loa (eye worm) calpain 0.0013 0.0028 0.008
Toxoplasma gondii ATPase/histidine kinase/DNA gyrase B/HSP90 domain-containing protein 0.0009 0.0008 0.0025
Echinococcus multilocularis g-protein coupled receptor 0.0031 0.0103 0.0168
Echinococcus granulosus tyrosine protein kinase Src64B 0.0012 0.0021 0.0035
Brugia malayi nuclear hormone receptor 0.0156 0.0634 0.1804
Trichomonas vaginalis DNA topoisomerase II, putative 0.0009 0.0008 0.0006
Onchocerca volvulus Protein ultraspiracle homolog 0.0156 0.0634 0.4995
Brugia malayi Steroid receptor seven-up type 2 0.0156 0.0634 0.1804
Leishmania major eukaryotic translation initiation factor-like 0.0046 0.0165 0.0264
Loa Loa (eye worm) hypothetical protein 0.0031 0.0103 0.0292
Loa Loa (eye worm) heat shock protein 75 0.004 0.0143 0.0406
Brugia malayi Type III restriction enzyme, res subunit family protein 0.0008 0.0005 0.0014
Echinococcus multilocularis Ataxin 2, N terminal,domain containing protein 0.0008 0.0005 0.0008
Mycobacterium tuberculosis Probable isocitrate dehydrogenase [NADP] Icd1 (oxalosuccinate decarboxylase) (IDH) (NADP+-specific ICDH) (IDP) 0.0011 0.0018 0.001
Echinococcus granulosus Nuclear hormone receptor family member nhr 41 0.0156 0.0634 0.1038
Loa Loa (eye worm) hypothetical protein 0.0074 0.0284 0.0808
Echinococcus granulosus calpain 5 0.0013 0.0028 0.0046
Trypanosoma brucei ATP-dependent DEAD/H DNA helicase recQ, putative 0.0009 0.0009 0.0008
Echinococcus granulosus tm gpcr rhodopsin 0.0031 0.0103 0.0168
Trypanosoma cruzi DNA repair protein, putative 0.0023 0.007 0.0107
Brugia malayi Nuclear hormone receptor family member nhr-3 0.0156 0.0634 0.1804
Brugia malayi hypothetical protein 0.0031 0.0103 0.0292
Brugia malayi DNA topoisomerase II, alpha isozyme 0.0009 0.0008 0.0024
Mycobacterium ulcerans recombinase A 0.0075 0.0291 0.0886
Trichomonas vaginalis CAMK family protein kinase 0.0163 0.0664 0.108
Plasmodium vivax ADP-dependent DNA helicase RecQ, putative 0.0011 0.0019 0.0045
Loa Loa (eye worm) hypothetical protein 0.0007 0.0002 0.0006
Schistosoma mansoni glutathione synthetase 0.0191 0.0784 0.1284
Echinococcus granulosus tyrosine protein kinase Lyn 0.0015 0.0033 0.0055
Loa Loa (eye worm) hypothetical protein 0.0031 0.0103 0.0292
Trichomonas vaginalis eukaryotic translation initiation factor 4E, putative 0.0046 0.0165 0.0263
Brugia malayi hypothetical protein 0.0018 0.0046 0.013
Schistosoma mansoni biogenic amine (5HT) receptor 0.0031 0.0103 0.0168
Mycobacterium ulcerans 4'-phosphopantetheinyl transferase 0.0016 0.0039 0.0095
Leishmania major AUT2/APG4/ATG4 cysteine peptidase, putative 0.0016 0.0039 0.0057
Loa Loa (eye worm) nuclear hormone receptor-like 1 0.0082 0.0321 0.0915
Loa Loa (eye worm) hypothetical protein 0.0031 0.0103 0.0292
Entamoeba histolytica recQ family helicase, putative 0.0009 0.0009 0.0008
Leishmania major heat shock protein, putative 0.004 0.0143 0.0226
Brugia malayi glutaminase DH11.1 0.0315 0.1309 0.3726
Brugia malayi Niemann-Pick C1 protein precursor 0.0069 0.0263 0.0747
Onchocerca volvulus 0.0011 0.0019 0.011
Trypanosoma cruzi heat shock protein, putative 0.004 0.0143 0.0226
Echinococcus multilocularis tyrosine protein kinase Src42A 0.0012 0.0021 0.0035
Trichomonas vaginalis AGC family protein kinase 0.0027 0.0084 0.0129
Plasmodium falciparum ataxin-2 like protein, putative 0.0018 0.0046 0.0142
Chlamydia trachomatis fructose-6-phosphate phosphotransferase 0.0018 0.005 0.0372
Brugia malayi Protein kinase domain containing protein 0.001 0.0014 0.004
Loa Loa (eye worm) gonadotropin-releasing hormone receptor 2 0.0031 0.0103 0.0292
Schistosoma mansoni amine GPCR 0.0031 0.0103 0.0168
Brugia malayi nuclear receptor NHR-88 0.0074 0.0284 0.0808
Brugia malayi G-protein coupled receptor 0.0031 0.0103 0.0292
Echinococcus granulosus geminin 0.0106 0.0424 0.0694
Mycobacterium ulcerans replicative DNA helicase DnaB 0.0269 0.1115 0.3474
Mycobacterium tuberculosis Possible two component transcriptional regulatory protein (probably LuxR-family) 0.054 0.2267 0.226
Leishmania major malonyl-coa decarboxylase-like protein 0.0328 0.1363 0.2227
Trypanosoma brucei isocitrate dehydrogenase, putative 0.0011 0.0018 0.0022
Entamoeba histolytica phosphofructokinase, putative 0.0068 0.0261 0.0421
Echinococcus granulosus chromodomain helicase DNA binding protein 4 0.0009 0.001 0.0016
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0031 0.0103 0.0168
Schistosoma mansoni serine/threonine protein kinase 0.0054 0.0202 0.033
Echinococcus granulosus L aminoadipate semialdehyde 0.0056 0.0211 0.0345
Entamoeba histolytica DNA topoisomerase II, putative 0.0009 0.0008 0.0006
Echinococcus multilocularis thyroid hormone receptor alpha 0.0156 0.0634 0.1038
Plasmodium vivax heat shock protein, putative 0.023 0.0949 0.296
Giardia lamblia Kinase, PLK 0.0163 0.0664 0.1086
Loa Loa (eye worm) hypothetical protein 0.0021 0.0058 0.0166
Mycobacterium ulcerans hypothetical protein 0.054 0.2267 0.7092
Brugia malayi gonadotropin-releasing hormone receptor 2 0.0031 0.0103 0.0292
Schistosoma mansoni retinoic acid receptor RXR 0.0156 0.0634 0.1038
Trypanosoma cruzi heat shock protein 85, putative 0.0061 0.0229 0.0368
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0031 0.0103 0.0168
Brugia malayi hypothetical protein 0.0011 0.0019 0.0054
Schistosoma mansoni nuclear hormone receptor 0.0156 0.0634 0.1038
Brugia malayi SEA domain containing protein 0.001 0.0016 0.0044
Echinococcus multilocularis serine threonine protein kinase 0.0027 0.0084 0.0137
Loa Loa (eye worm) TK/ABL protein kinase 0.001 0.0014 0.004
Leishmania major heat shock protein 83-1 0.0061 0.0229 0.0368
Echinococcus multilocularis bloom syndrome protein 0.0017 0.0042 0.0069
Loa Loa (eye worm) Smad1 0.0011 0.0017 0.0048
Echinococcus granulosus tar DNA binding protein 0.0044 0.0159 0.026
Trypanosoma cruzi kinesin, putative 0.0013 0.0028 0.0038
Schistosoma mansoni tyrosine kinase 0.0012 0.0021 0.0035
Schistosoma mansoni amine GPCR 0.0031 0.0103 0.0168
Schistosoma mansoni defective proboscis extension response (dpr)-related 0.0017 0.0043 0.007
Loa Loa (eye worm) hypothetical protein 0.0074 0.0284 0.0808
Echinococcus multilocularis insulin growth factor 1 receptor beta 0.0037 0.0127 0.0209
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0012 0.0024 0.0032
Echinococcus multilocularis 7TM GPCR, rhodopsin 0.0031 0.0103 0.0168
Plasmodium vivax rac-beta serine/threonine protein kinase, putative 0.0049 0.018 0.055
Toxoplasma gondii NAC domain-containing protein 0.0024 0.0075 0.0232
Schistosoma mansoni heat shock protein 0.0061 0.0229 0.0375
Loa Loa (eye worm) neuropeptide F receptor 0.0031 0.0103 0.0292
Loa Loa (eye worm) TOPoisomerase family member 0.0009 0.0008 0.0024
Loa Loa (eye worm) hypothetical protein 0.0082 0.0321 0.0915
Loa Loa (eye worm) hypothetical protein 0.0031 0.0103 0.0292
Mycobacterium ulcerans geranylgeranyl pyrophosphate synthase 0.0758 0.3193 1
Schistosoma mansoni amine GPCR 0.0031 0.0103 0.0168
Loa Loa (eye worm) hypothetical protein 0.0011 0.0019 0.0054
Schistosoma mansoni aminoadipate-semialdehyde dehydrogenase 0.0056 0.0211 0.0345
Brugia malayi GnHR receptor homolog 0.0031 0.0103 0.0292
Trichomonas vaginalis heat shock protein, putative 0.0057 0.0213 0.0341
Trypanosoma cruzi cysteine peptidase, Clan CA, family C2, putative 0.0013 0.0028 0.0038
Toxoplasma gondii chromodomain helicase DNA binding protein CHD1/SWI2/SNF2 0.0008 0.0005 0.0014
Echinococcus granulosus tyrosine protein kinase shark 0.001 0.0014 0.0023
Echinococcus granulosus chromodomain helicase DNA binding protein 1 0.0008 0.0005 0.0008
Echinococcus granulosus thyroid hormone receptor alpha 0.0074 0.0284 0.0465
Echinococcus granulosus G protein coupled 5 hydroxytryptamine receptor 0.0031 0.0103 0.0168
Echinococcus multilocularis nuclear receptor subfamily 4 group A 0.0074 0.0284 0.0465
Onchocerca volvulus 0.001 0.0014 0.0072
Schistosoma mansoni tar DNA-binding protein 0.0044 0.0159 0.026
Echinococcus granulosus dual specificity testis-specific protein kinase 0.0008 0.0005 0.0007
Echinococcus multilocularis tyrosine protein kinase Abl 0.0012 0.0021 0.0035
Onchocerca volvulus Phospholipase A2 homolog 0.0304 0.1265 1
Plasmodium falciparum heat shock protein 90 0.0061 0.0229 0.0716
Trypanosoma cruzi rac serine-threonine kinase, putative 0.0049 0.018 0.0288
Schistosoma mansoni neuropeptide receptor 0.0216 0.089 0.1457
Loa Loa (eye worm) hypothetical protein 0.0031 0.0103 0.0292
Echinococcus granulosus heat shock protein 75 kDa mitochondrial 0.004 0.0143 0.0233
Trypanosoma brucei heat shock protein 84, putative 0.004 0.0143 0.0226
Schistosoma mansoni myosin xvIII 0.0031 0.0103 0.0168
Echinococcus multilocularis transcription factor btf3 0.0024 0.0075 0.0122
Echinococcus granulosus rhodopsin orphan GPCR 0.0031 0.0103 0.0168
Schistosoma mansoni chromobox protein 0.0049 0.0177 0.0291
Loa Loa (eye worm) hypothetical protein 0.0008 0.0005 0.0014
Brugia malayi Melatonin receptor type 1A 0.0031 0.0103 0.0292
Echinococcus granulosus rhodopsin orphan GPCR 0.0031 0.0103 0.0168
Onchocerca volvulus 0.002 0.0056 0.0407
Schistosoma mansoni gcn5proteinral control of amino-acid synthesis 5-like 2 gcnl2 0.0098 0.0389 0.0637
Onchocerca volvulus 0.0021 0.0062 0.0451
Echinococcus multilocularis basement membrane specific heparan sulfate 0.0019 0.0051 0.0083
Brugia malayi Protein kinase domain containing protein 0.001 0.0014 0.004
Onchocerca volvulus 0.0031 0.0103 0.0775
Echinococcus multilocularis mitogen activated protein kinase 0.0054 0.0202 0.033
Entamoeba histolytica serine/threonine protein kinase, putative 0.0163 0.0664 0.108
Schistosoma mansoni nuclear receptor 0.0074 0.0284 0.0465
Toxoplasma gondii 6-phosphofructokinase 0.0018 0.005 0.0154
Echinococcus granulosus calcium:calmodulin dependent protein kinase 0.0049 0.018 0.0295
Trypanosoma cruzi calpain cysteine peptidase, putative 0.0013 0.0028 0.0038
Schistosoma mansoni ecdysone-induced protein 78c (dr-78) 0.0082 0.0321 0.0526
Brugia malayi heat shock protein 90 0.0061 0.0229 0.0652
Leishmania major heat shock protein 83-1 0.0061 0.0229 0.0368
Entamoeba histolytica protein kinase, putative 0.0016 0.004 0.0058
Schistosoma mansoni amine GPCR 0.0031 0.0103 0.0168
Onchocerca volvulus 0.001 0.0016 0.0084
Schistosoma mansoni survival motor neuron protein 0.0064 0.0243 0.0397
Trypanosoma brucei calpain-like cysteine peptidase, putative 0.0013 0.0028 0.0038
Onchocerca volvulus 0.0094 0.0369 0.2891
Brugia malayi RNA recognition motif domain containing protein 0.0044 0.0159 0.0452
Brugia malayi hypothetical protein 0.0031 0.0103 0.0292
Schistosoma mansoni patched 1 0.0029 0.0096 0.0158
Loa Loa (eye worm) hypothetical protein 0.0031 0.0103 0.0292
Entamoeba histolytica eukaryotic translation initiation factor 4E, putative 0.0046 0.0165 0.0264
Echinococcus multilocularis Protein kinase C, brain isozyme 0.0027 0.0084 0.0137
Echinococcus multilocularis heat shock protein 0.0061 0.0229 0.0375
Brugia malayi Furin-like cysteine rich region family protein 0.0106 0.042 0.1195
Echinococcus granulosus rhodopsin orphan GPCR 0.0031 0.0103 0.0168
Echinococcus granulosus orexin receptor type 2 0.0031 0.0103 0.0168
Trypanosoma cruzi mitogen-activated protein kinase 11, putative 0.0054 0.0202 0.0323
Brugia malayi Peptidase family C54 containing protein 0.0041 0.0146 0.0415
Loa Loa (eye worm) hypothetical protein 0.0021 0.0058 0.0166
Mycobacterium leprae RECA PROTEIN (RECOMBINASE A) [CONTAINS: Mle RECA INTEIN]. 0.0075 0.0291 0.0846
Echinococcus multilocularis serine:threonine protein kinase N2 0.0027 0.0084 0.0137
Entamoeba histolytica chromodomain-helicase-DNA-binding protein, putative 0.0008 0.0005 0.0001
Brugia malayi G protein-coupled receptor F59B2.13 0.0031 0.0103 0.0292
Plasmodium vivax isocitrate dehydrogenase [NADP], mitochondrial, putative 0.0011 0.0018 0.0041
Echinococcus granulosus eukaryotic translation initiation factor 4E 0.0046 0.0165 0.0271
Trypanosoma brucei solanesyl-diphosphate synthase, putative 0.0191 0.0784 0.1278
Toxoplasma gondii ATP-dependent DNA helicase, RecQ family protein 0.0011 0.0019 0.0057
Trichomonas vaginalis receptor histidine kinase, putative 0.0009 0.0008 0.0006
Trypanosoma brucei isocitrate dehydrogenase [NADP], mitochondrial precursor, putative 0.0011 0.0018 0.0022
Echinococcus granulosus neurotracting:lsamp:neurotrimin:obcam 0.0019 0.0052 0.0084
Brugia malayi Latrophilin receptor protein 2 0.0032 0.0107 0.0304
Schistosoma mansoni Replicative DNA helicase 0.0269 0.1115 0.1825
Echinococcus granulosus ATP dependent DNA helicase PIF1 0.1444 0.6107 1
Trypanosoma cruzi malonyl-CoA decarboxylase, mitochondrial precursor, putative 0.0328 0.1363 0.2227
Echinococcus granulosus ATP dependent DNA helicase Q5 0.0007 0.0001 0.0001
Loa Loa (eye worm) hypothetical protein 0.0008 0.0005 0.0014
Loa Loa (eye worm) hypothetical protein 0.0032 0.0107 0.0304
Loa Loa (eye worm) isocitrate dehydrogenase 0.0011 0.0018 0.0051
Schistosoma mansoni cpg binding protein 0.0021 0.0061 0.01
Echinococcus granulosus chromobox protein 1 0.0049 0.0177 0.0291
Echinococcus multilocularis tyrosine protein kinase Fyn 0.001 0.0014 0.0023
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0042 0.0152 0.0248
Echinococcus multilocularis smad 0.0011 0.0017 0.0028
Brugia malayi sulfakinin receptor protein 0.0031 0.0103 0.0292
Brugia malayi Protein kinase domain containing protein 0.0027 0.0084 0.0239
Schistosoma mansoni NADP-specific isocitrate dehydrogenase 0.0011 0.0018 0.0029
Loa Loa (eye worm) RNA recognition domain-containing protein domain-containing protein 0.0044 0.0159 0.0452
Echinococcus multilocularis nervana 2 0.0046 0.0168 0.0275
Treponema pallidum HPr kinase/phosphorylase 0.0552 0.2318 1
Echinococcus multilocularis survival motor neuron protein 1 0.0313 0.1302 0.2132
Trypanosoma cruzi AUT2/APG4/ATG4 cysteine peptidase, putative 0.0041 0.0146 0.0231
Echinococcus granulosus protein kinase C gamma type 0.0027 0.0084 0.0137
Onchocerca volvulus 0.0031 0.0103 0.0775
Echinococcus multilocularis nuclear factor of activated T cells 5 0.0037 0.013 0.0213
Loa Loa (eye worm) TK/FER protein kinase 0.001 0.0014 0.004
Loa Loa (eye worm) endoplasmin 0.0061 0.0229 0.0652
Echinococcus granulosus COUP TF:Svp nuclear hormone receptor 0.0156 0.0634 0.1038
Loa Loa (eye worm) hypothetical protein 0.0011 0.0019 0.0054
Entamoeba histolytica Niemann-Pick C1 protein, putative 0.0069 0.0263 0.0423
Onchocerca volvulus 0.0156 0.0634 0.4995
Brugia malayi nuclear hormone receptor 0.0074 0.0284 0.0808
Schistosoma mansoni chromodomain helicase DNA binding protein 0.0008 0.0005 0.0008
Trypanosoma brucei heat shock protein, putative 0.0061 0.0229 0.0368
Brugia malayi Associated with TFs and helicases family protein 0.0008 0.0005 0.0014
Loa Loa (eye worm) hypothetical protein 0.0017 0.0043 0.0122
Trichomonas vaginalis glutaminase, putative 0.0315 0.1309 0.2137
Schistosoma mansoni tar DNA-binding protein 0.0044 0.0159 0.026
Brugia malayi chromobox protein homolog 3 0.0027 0.0087 0.0247
Brugia malayi conserved hypotetical protein 0.0074 0.0284 0.0808
Echinococcus multilocularis tyrosine protein kinase lyn tyrosine protein kinase blk 0.0012 0.0021 0.0035
Echinococcus granulosus insulin growth factor 1 receptor beta 0.0037 0.0127 0.0209
Plasmodium vivax DNA topoisomerase II, putative 0.0009 0.0008 0.0011
Leishmania major mitochondrial DNA topoisomerase II 0.0009 0.0008 0.0006
Schistosoma mansoni hypothetical protein 0.0008 0.0005 0.0008
Echinococcus granulosus farnesyl pyrophosphate synthase 0.0758 0.3193 0.5228
Loa Loa (eye worm) hypothetical protein 0.0033 0.0112 0.032
Brugia malayi AKH receptor 0.0031 0.0103 0.0292
Echinococcus granulosus ecdysone induced protein 78C 0.0156 0.0634 0.1038
Brugia malayi putative malonyl-CoA decarboxylase 0.0834 0.3514 1
Echinococcus multilocularis c src tyrosine kinase 0.0012 0.0021 0.0035
Echinococcus granulosus biogenic amine 5HT receptor 0.0031 0.0103 0.0168
Echinococcus granulosus FTZ F1 alpha 0.0156 0.0634 0.1038
Echinococcus multilocularis Immunoglobulin 0.0017 0.0043 0.007
Leishmania major heat shock protein 83-1 0.0061 0.0229 0.0368
Loa Loa (eye worm) hypothetical protein 0.0031 0.0103 0.0292
Trypanosoma brucei heat shock protein, putative 0.0061 0.0229 0.0368
Trichomonas vaginalis heat shock protein, putative 0.0061 0.0229 0.0367
Brugia malayi hypothetical protein 0.0031 0.0103 0.0292
Brugia malayi hypothetical protein 0.0313 0.1302 0.3706
Entamoeba histolytica heat shock protein 90, putative 0.0061 0.0229 0.0368
Echinococcus granulosus retinoic acid receptor rxr beta a 0.0156 0.0634 0.1038
Brugia malayi Corticotropin releasing factor receptor 2 precursor, putative 0.0101 0.0399 0.1136
Schistosoma mansoni hypothetical protein 0.0028 0.0092 0.015
Plasmodium vivax heat shock protein 90, putative 0.004 0.0143 0.0432
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0031 0.0103 0.0168
Toxoplasma gondii calcium dependent protein kinase CDPK8 0.0008 0.0005 0.0012
Onchocerca volvulus Bile acid receptor homolog 0.0156 0.0634 0.4995
Trypanosoma brucei Eukaryotic translation initiation factor 4E-1 0.0046 0.0165 0.0264
Chlamydia trachomatis recombinase RecA 0.0075 0.0291 0.255
Echinococcus granulosus twitchin 0.0021 0.0062 0.0101
Echinococcus multilocularis nervana 2 0.0046 0.0168 0.0275
Leishmania major heat shock protein 83-1 0.0061 0.0229 0.0368
Loa Loa (eye worm) nuclear receptor nhr-7B 0.0074 0.0284 0.0808
Mycobacterium tuberculosis Probable multifunctional geranylgeranyl pyrophosphate synthetase IdsA1 (GGPP synthetase) (ggppsase) (geranylgeranyl diphosphate 0.0191 0.0784 0.0776
Trichomonas vaginalis AGC family protein kinase 0.0027 0.0084 0.0129
Toxoplasma gondii phosphofructokinase PFKII 0.0018 0.005 0.0154
Trypanosoma brucei heat shock protein, putative 0.0061 0.0229 0.0368
Giardia lamblia Pms1-like protein 0.0009 0.0008 0.0013
Entamoeba histolytica acetyltransferase, GNAT family 0.0027 0.0084 0.013
Onchocerca volvulus 0.001 0.0016 0.0084
Chlamydia trachomatis fructose-6-phosphate phosphotransferase 0.0018 0.005 0.0372
Schistosoma mansoni opsin-like receptor 0.0031 0.0103 0.0168
Loa Loa (eye worm) hypothetical protein 0.0082 0.0321 0.0915
Schistosoma mansoni hypothetical protein 0.0028 0.0092 0.015
Echinococcus multilocularis nuclear receptor nhr 48 0.0074 0.0284 0.0465
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0031 0.0103 0.0168
Echinococcus granulosus 7tm_1 domain containing protein 0.0031 0.0103 0.0168
Loa Loa (eye worm) hypothetical protein 0.0156 0.0634 0.1804
Loa Loa (eye worm) AGC/PKN protein kinase 0.0027 0.0084 0.0239
Entamoeba histolytica DNA repair and recombination protein, putative 0.1444 0.6107 1
Echinococcus multilocularis serine threonine protein kinase nrc serine threonine protein kinase gad 0.0049 0.018 0.0295
Trypanosoma cruzi cysteine peptidase, Clan CA, family C2, putative 0.0013 0.0028 0.0038
Brugia malayi hypothetical protein 0.0218 0.0897 0.2551
Brugia malayi calpain 7 0.0013 0.0028 0.008
Echinococcus granulosus neuropeptide FF receptor 2 0.0031 0.0103 0.0168
Echinococcus multilocularis growth hormone secretagogue receptor type 1 0.0031 0.0103 0.0168
Echinococcus granulosus Nuclear hormone receptor HR96 0.0074 0.0284 0.0465
Brugia malayi SH2 domain containing protein 0.001 0.0014 0.004
Echinococcus granulosus calpain A 0.0013 0.0028 0.0046
Leishmania major PIF1 helicase-like protein, putative,DNA repair and recombination protein, mitochondrial precursor, putative 0.1444 0.6107 1
Trypanosoma brucei heat shock protein, putative 0.0061 0.0229 0.0368
Trichomonas vaginalis receptor histidine kinase, putative 0.0009 0.0008 0.0006
Brugia malayi nuclear receptor RXR 0.0082 0.0321 0.0915
Leishmania major ATP-dependent DEAD/H DNA helicase recQ, putative 0.0009 0.0009 0.0008
Echinococcus multilocularis atpase aaa+ type core atpase aaa type core 0.0565 0.2371 0.3882
Schistosoma mansoni hypothetical protein 0.0031 0.0103 0.0168
Schistosoma mansoni nuclear receptor 0.0074 0.0284 0.0465
Brugia malayi RE15519p 0.0031 0.0103 0.0292
Echinococcus multilocularis thyrotropin releasing hormone receptor 0.0031 0.0103 0.0168
Leishmania major mitogen activated protein kinase, putative,map kinase, putative 0.0054 0.0202 0.0323
Brugia malayi orphan nuclear receptor NR2E1 0.0074 0.0284 0.0808
Echinococcus multilocularis g protein coupled receptor 0.0031 0.0103 0.0168
Leishmania major hypothetical protein, conserved 0.0009 0.0008 0.0006
Echinococcus multilocularis allatostatin A receptor 0.0031 0.0103 0.0168
Brugia malayi ecdysone receptor 0.0074 0.0284 0.0808
Loa Loa (eye worm) G-protein coupled receptor 0.0031 0.0103 0.0292
Trichomonas vaginalis CMGC family protein kinase 0.0054 0.0202 0.0322
Brugia malayi hypothetical protein 0.0031 0.0103 0.0292
Echinococcus multilocularis calpain family protein 1, d 0.0032 0.0105 0.0172
Brugia malayi Tyrosine-protein kinase abl-1 0.0012 0.0021 0.006
Onchocerca volvulus 0.0031 0.0103 0.0775
Trypanosoma cruzi DNA repair and recombination helicase protein PIF6, putative 0.1444 0.6107 1
Echinococcus multilocularis epidermal growth factor receptor 0.0106 0.042 0.0688
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0061 0.0229 0.0375
Loa Loa (eye worm) hypothetical protein 0.0031 0.0103 0.0292
Echinococcus granulosus Chromo domain 0.0008 0.0005 0.0008
Schistosoma mansoni biogenic amine receptor 0.0031 0.0103 0.0168
Trichomonas vaginalis conserved hypothetical protein 0.1444 0.6107 1
Mycobacterium ulcerans 6-phosphofructokinase 0.0068 0.0261 0.0794
Schistosoma mansoni geranylgeranyl pyrophosphate synthase 0.0191 0.0784 0.1284
Trichomonas vaginalis eukaryotic translation initiation factor 4E, putative 0.0046 0.0165 0.0263
Loa Loa (eye worm) hypothetical protein 0.0018 0.0046 0.013
Brugia malayi Nuclear hormone receptor E75 0.0074 0.0284 0.0808
Loa Loa (eye worm) hypothetical protein 0.0032 0.0105 0.0299
Echinococcus granulosus family C2 unassigned peptidase C02 family 0.0047 0.0172 0.0281
Toxoplasma gondii CMGC kinase, MAPK family (ERK) MAPK-1 0.0054 0.0202 0.063
Echinococcus granulosus nervana 2 0.0046 0.0168 0.0275
Mycobacterium leprae PROBABLE REPLICATIVE DNA HELICASE DNAB replicative DNA helicase 0.0269 0.1115 0.3318
Echinococcus multilocularis mothers against decapentaplegic 5 0.0011 0.0017 0.0028
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0012 0.0024 0.0032
Loa Loa (eye worm) hypothetical protein 0.0074 0.0284 0.0808
Schistosoma mansoni calpain C (C02 family) 0.0013 0.0028 0.0046
Loa Loa (eye worm) hypothetical protein 0.0031 0.0103 0.0292
Echinococcus granulosus nuclear receptor subfamily 4 group A 0.0074 0.0284 0.0465
Toxoplasma gondii ATPase/histidine kinase/DNA gyrase B/HSP90 domain-containing protein 0.0009 0.0008 0.0025
Schistosoma mansoni smad1 5 8 and 0.0011 0.0017 0.0028
Brugia malayi Dopamine receptor protein 2 0.0031 0.0103 0.0292
Echinococcus granulosus heat shock protein 0.0061 0.0229 0.0375
Brugia malayi Immunoglobulin I-set domain containing protein 0.0009 0.0011 0.0031
Loa Loa (eye worm) hypothetical protein 0.0008 0.0005 0.0014
Echinococcus granulosus endoplasmin 0.0057 0.0213 0.0349
Brugia malayi Protein kinase domain containing protein 0.0218 0.09 0.256
Echinococcus granulosus NADP dependent isocitrate dehydrogenase 0.0011 0.0018 0.0029
Echinococcus multilocularis Chromo domain 0.0008 0.0005 0.0008
Mycobacterium leprae PROBABLE TRANSCRIPTIONAL REGULATORY PROTEIN 0.054 0.2267 0.6773
Schistosoma mansoni thyroid hormone receptor 0.0156 0.0634 0.1038
Onchocerca volvulus Tyrosine kinase homolog 0.01 0.0397 0.3113
Loa Loa (eye worm) abnormal chemotaxis protein 14 0.0029 0.0096 0.0274
Schistosoma mansoni photoreceptor-specific nuclear receptor related 0.0156 0.0634 0.1038
Schistosoma mansoni DNA helicase recq5 0.0007 0.0001 0.0001
Echinococcus granulosus nervana 2 0.0046 0.0168 0.0275
Leishmania major heat shock protein 83-1 0.0061 0.0229 0.0368
Echinococcus multilocularis pyroglutamylated rfamide peptide receptor 0.0031 0.0103 0.0168
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0156 0.0634 0.1038
Echinococcus granulosus sterol regulatory element binding protein 0.0029 0.0096 0.0158
Plasmodium falciparum cysteine protease ATG4, putative 0.0016 0.0039 0.0121
Schistosoma mansoni Tr4/Tr2 (homologue) 0.0156 0.0634 0.1038
Echinococcus multilocularis cadherin EGF LAG seven pass G type receptor 0.0032 0.0107 0.0175
Loa Loa (eye worm) hypothetical protein 0.0017 0.0043 0.0122
Loa Loa (eye worm) GTP-binding regulatory protein Gs alpha-S chain 0.0061 0.0229 0.0651
Echinococcus multilocularis neuropeptide receptor 0.0216 0.089 0.1457
Onchocerca volvulus Heterochromatin protein 1 homolog 0.0027 0.0087 0.065
Plasmodium falciparum geranylgeranyl pyrophosphate synthase, putative 0.0758 0.3193 1
Entamoeba histolytica eukaryotic translation initiation factor 4E, putative 0.0046 0.0165 0.0264
Loa Loa (eye worm) translation initiation factor 4E 0.0046 0.0165 0.0471
Schistosoma mansoni tyrosine kinase 0.0054 0.02 0.0327
Echinococcus granulosus neuropeptide Y receptor 0.0031 0.0103 0.0168
Leishmania major eukaryotic translation initiation factor-like protein 0.0046 0.0165 0.0264
Schistosoma mansoni hypothetical protein 0.1444 0.6107 1
Loa Loa (eye worm) heat shock protein 90 0.0061 0.0229 0.0652
Onchocerca volvulus 0.0031 0.0103 0.0775
Brugia malayi hypothetical protein 0.0085 0.0334 0.095
Brugia malayi Dopamine receptor 0.0031 0.0103 0.0292
Brugia malayi putative neuropeptide receptor 0.0031 0.0103 0.0292
Echinococcus multilocularis endoplasmin 0.0057 0.0213 0.0349
Brugia malayi Polyprenyl synthetase family protein 0.0758 0.3193 0.9085
Schistosoma mansoni hypothetical protein 0.026 0.1077 0.1763
Plasmodium falciparum chromodomain-helicase-DNA-binding protein 1 homolog, putative 0.0008 0.0005 0.0014
Echinococcus multilocularis cysteine protease atg4b 0.0041 0.0146 0.0239
Loa Loa (eye worm) nuclear receptor NHR-67 0.0074 0.0284 0.0808
Schistosoma mansoni histamine h1 receptor 0.0031 0.0103 0.0168
Mycobacterium tuberculosis Possible transcriptional regulatory protein 0.054 0.2267 0.226
Loa Loa (eye worm) glutaminase 2 0.0315 0.1309 0.3726
Schistosoma mansoni smad1 5 8 and 0.0011 0.0017 0.0028
Onchocerca volvulus 0.0031 0.0103 0.0775
Loa Loa (eye worm) hypothetical protein 0.0036 0.0124 0.0354
Echinococcus multilocularis serotonin receptor 0.0031 0.0103 0.0168
Echinococcus granulosus g protein coupled receptor 0.0031 0.0103 0.0168
Toxoplasma gondii autophagy-related cysteine peptidase atg4, putative 0.0016 0.0039 0.0121
Toxoplasma gondii heat shock protein 90, putative 0.0061 0.0229 0.0716
Schistosoma mansoni neuropeptide receptor 0.0031 0.0103 0.0168
Echinococcus granulosus cysteine protease atg4b 0.0041 0.0146 0.0239
Echinococcus granulosus prenyl decaprenyl diphosphate synthase 0.0191 0.0784 0.1284
Loa Loa (eye worm) hypothetical protein 0.0085 0.0334 0.095
Echinococcus granulosus tyrosine protein kinase Btk29A 0.0102 0.0404 0.0661
Echinococcus multilocularis heat shock protein 90 0.0061 0.0229 0.0375
Onchocerca volvulus Huntingtin homolog 0.0085 0.0334 0.261
Brugia malayi beta-NAC-like protein 0.0024 0.0075 0.0213
Echinococcus granulosus tyrosine protein kinase Fyn 0.0012 0.0021 0.0035
Echinococcus granulosus serine:threonine protein kinase PLK1 0.0163 0.0664 0.1087
Loa Loa (eye worm) hypothetical protein 0.0031 0.0103 0.0292
Onchocerca volvulus 0.0011 0.0019 0.011
Loa Loa (eye worm) hypothetical protein 0.0031 0.0103 0.0292
Echinococcus granulosus Niemann Pick C1 protein 0.0098 0.0388 0.0635
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0012 0.0024 0.0032
Echinococcus multilocularis peptide (allatostatin:somatostatin) 0.0031 0.0103 0.0168
Onchocerca volvulus 0.0031 0.0103 0.0775
Trypanosoma cruzi mitogen activated protein kinase 2, putative 0.0054 0.0202 0.0323
Echinococcus multilocularis mitogen activated protein kinase 3 0.0054 0.0202 0.033
Schistosoma mansoni family C2 unassigned peptidase (C02 family) 0.0047 0.0172 0.0281
Brugia malayi DNA gyrase/topoisomerase IV, A subunit family protein 0.0009 0.0008 0.0024
Toxoplasma gondii LsmAD domain-containing protein 0.0018 0.0046 0.0142
Echinococcus granulosus Smad4 0.0011 0.0017 0.0028
Onchocerca volvulus Nuclear receptor subfamily 6 group A member 1 homolog 0.0074 0.0284 0.2215
Loa Loa (eye worm) hypothetical protein 0.0017 0.0043 0.0122
Entamoeba histolytica peptidase, C54 family 0.0016 0.0039 0.0057
Plasmodium falciparum DNA gyrase subunit B 0.0009 0.0008 0.0025
Loa Loa (eye worm) hypothetical protein 0.0031 0.0103 0.0292
Trypanosoma cruzi developmentally regulated phosphoprotein, putative 0.0009 0.0008 0.0006
Schistosoma mansoni cpg binding protein 0.0021 0.0061 0.01
Brugia malayi larval opioid receptor 0.0031 0.0103 0.0292
Echinococcus multilocularis serine:threonine protein kinase 38 0.0027 0.0084 0.0137
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0031 0.0103 0.0168
Echinococcus multilocularis DNA topoisomerase 2 alpha 0.0009 0.0008 0.0014
Loa Loa (eye worm) glutaminase 0.0315 0.1309 0.3726
Echinococcus granulosus tyrosine protein kinase Fps85D 0.001 0.0014 0.0023
Loa Loa (eye worm) nuclear hormone receptor family member nhr-14 0.0156 0.0634 0.1804
Loa Loa (eye worm) hypothetical protein 0.0064 0.0244 0.0693
Toxoplasma gondii histone lysine methyltransferase SET1 0.004 0.0142 0.0445
Loa Loa (eye worm) hypothetical protein 0.0017 0.0043 0.0122
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0012 0.0024 0.0032
Loa Loa (eye worm) hypothetical protein 0.0031 0.0103 0.0292
Schistosoma mansoni biogenic amine receptor 0.0031 0.0103 0.0168
Trichomonas vaginalis sensory transduction histidine kinase bacterial, putative 0.0009 0.0008 0.0006
Toxoplasma gondii polyprenyl synthetase superfamily protein 0.0191 0.0784 0.2455
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0156 0.0634 0.1804
Toxoplasma gondii Hsp90 domain-containing protein 0.023 0.0949 0.297
Trypanosoma cruzi calpain-like cysteine peptidase, putative 0.0013 0.0028 0.0038
Entamoeba histolytica hypothetical protein 0.0008 0.0005 0.0001
Loa Loa (eye worm) hypothetical protein 0.0009 0.0008 0.0024
Loa Loa (eye worm) hypothetical protein 0.0031 0.0103 0.0292
Loa Loa (eye worm) nuclear hormone receptor family member nhr-31 0.0156 0.0634 0.1804
Brugia malayi Nuclear hormone receptor E75 0.0074 0.0284 0.0808
Echinococcus granulosus tyrosine protein kinase Blk 0.001 0.0014 0.0023
Echinococcus granulosus sodium:potassium dependent atpase beta subunit 0.0046 0.0168 0.0275
Toxoplasma gondii ATPase/histidine kinase/DNA gyrase B/HSP90 domain-containing protein 0.0009 0.0008 0.0025
Echinococcus granulosus Pyruvate dehydrogenase lipoamide kinase 0.0009 0.0008 0.0014
Brugia malayi hypothetical protein 0.0082 0.0321 0.0915
Trichomonas vaginalis AGC family protein kinase 0.003 0.01 0.0155
Brugia malayi hypothetical protein 0.0031 0.0103 0.0292
Loa Loa (eye worm) TK protein kinase 0.001 0.0014 0.004
Brugia malayi hypothetical protein 0.0074 0.0284 0.0808
Plasmodium falciparum endoplasmin, putative 0.0044 0.0158 0.0495
Schistosoma mansoni hypothetical protein 0.0011 0.0019 0.0031
Schistosoma mansoni DNA helicase recq1 0.0007 0.0001 0.0001
Onchocerca volvulus 0.0031 0.0103 0.0775
Trichomonas vaginalis conserved hypothetical protein 0.0027 0.0087 0.0134
Brugia malayi Bloom's syndrome protein homolog 0.0017 0.0042 0.012
Loa Loa (eye worm) polyprenyl synthetase 0.0191 0.0784 0.2231
Plasmodium vivax DNA gyrase subunit B, putative 0.0009 0.0008 0.0011
Schistosoma mansoni thyrotropin-releasing hormone receptor 0.0031 0.0103 0.0168
Entamoeba histolytica protein kinase, putative 0.0077 0.0297 0.0479
Trypanosoma cruzi mitogen activated protein kinase 4, putative 0.0054 0.0202 0.0323
Onchocerca volvulus 0.0031 0.0103 0.0775
Brugia malayi Protein kinase domain containing protein 0.0037 0.0127 0.0362
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0031 0.0103 0.0168
Loa Loa (eye worm) hypothetical protein 0.0031 0.0103 0.0292
Loa Loa (eye worm) CAMK/CAMKL/CHK1 protein kinase 0.0116 0.0465 0.1322
Trichomonas vaginalis AGC family protein kinase 0.0077 0.0297 0.0478
Loa Loa (eye worm) hypothetical protein 0.0017 0.0043 0.0122
Echinococcus granulosus DNA topoisomerase 2 alpha 0.0009 0.0008 0.0014
Trypanosoma cruzi mitochondrial DNA topoisomerase II, putative 0.0009 0.0008 0.0006
Schistosoma mansoni peptide (FMRFamide/somatostatin)-like receptor 0.0031 0.0103 0.0168
Echinococcus granulosus tachykinin peptides receptor 99D 0.0031 0.0103 0.0168
Giardia lamblia Pyrophosphate-fructose 6-phosphate 1-phosphotransferase alpha subunit 0.0018 0.005 0.008
Mycobacterium ulcerans phosphopantetheinyl transferase, PptII 0.0016 0.0039 0.0095
Echinococcus multilocularis proto oncogene tyrosine protein kinase LCK 0.0012 0.0021 0.0035
Brugia malayi ecdysteroid receptor 0.0156 0.0634 0.1804
Loa Loa (eye worm) twinkle helicase 0.0077 0.0298 0.0848
Schistosoma mansoni neuropeptide F-like receptor 0.0031 0.0103 0.0168
Echinococcus multilocularis Chromobox protein 3 0.0008 0.0005 0.0008
Loa Loa (eye worm) hypothetical protein 0.0101 0.0399 0.1136
Leishmania major hypothetical protein, conserved 0.0018 0.0046 0.0068
Loa Loa (eye worm) AGC/NDR protein kinase 0.0027 0.0084 0.0239
Entamoeba histolytica hypothetical protein 0.0008 0.0005 0.0001
Onchocerca volvulus Serine\/threonine protein kinase homolog 0.0218 0.09 0.7104
Loa Loa (eye worm) hypothetical protein 0.0031 0.0103 0.0292
Mycobacterium tuberculosis Probable transcriptional regulatory protein 0.054 0.2267 0.226
Entamoeba histolytica protein kinase 2, putative 0.0049 0.018 0.0288
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0031 0.0103 0.0168
Leishmania major heat shock protein 83-1 0.0061 0.0229 0.0368
Loa Loa (eye worm) hypothetical protein 0.0007 0.0001 0.0002
Onchocerca volvulus Serine\/threonine kinase homolog 0.0163 0.0664 0.5231
Trichomonas vaginalis two component sensor and regulator histidine kinase bacteria, putative 0.0009 0.0008 0.0006
Echinococcus multilocularis ribosomal protein S6 kinase alpha 3 0.0027 0.0084 0.0137
Mycobacterium tuberculosis Probable chaperone protein HtpG (heat shock protein) (HSP90 family protein) (high temperature protein G) 0.0057 0.0213 0.0205
Echinococcus granulosus neuropeptide receptor A26 0.0031 0.0103 0.0168
Echinococcus multilocularis g protein linked acetylcholine receptor gar 2a 0.0031 0.0103 0.0168
Schistosoma mansoni hypothetical protein 0.0201 0.0824 0.1349
Schistosoma mansoni Mername-AA248 (C02 family) 0.0013 0.0028 0.0046
Echinococcus granulosus rhodopsin orphan GPCR 0.0031 0.0103 0.0168
Loa Loa (eye worm) hypothetical protein 0.0031 0.0103 0.0292
Echinococcus granulosus GPCR family 2 0.0032 0.0107 0.0175
Brugia malayi hypothetical protein 0.0031 0.0103 0.0292
Loa Loa (eye worm) AGC/DMPK/GEK protein kinase 0.0027 0.0084 0.0239
Echinococcus multilocularis Ankyrin 0.0007 0.0003 0.0004
Loa Loa (eye worm) hypothetical protein 0.0031 0.0103 0.0292
Toxoplasma gondii 4'-phosphopantetheinyl transferase domain-containing protein 0.0016 0.0039 0.0119
Schistosoma mansoni hypothetical protein 0.0028 0.0092 0.015
Echinococcus granulosus Protein patched homolog 1 0.0029 0.0096 0.0158
Plasmodium falciparum conserved Plasmodium protein, unknown function 0.0008 0.0005 0.0014
Loa Loa (eye worm) DR-78 0.0074 0.0284 0.0808
Schistosoma mansoni niemann-pick C1 (NPC1) 0.007 0.0267 0.0437
Trichomonas vaginalis phosphofructokinase, putative 0.0068 0.0261 0.042
Entamoeba histolytica pyrophosphate-dependent phosphofructokinase 0.0018 0.005 0.0074
Schistosoma mansoni hypothetical protein 0.0008 0.0005 0.0008
Trypanosoma cruzi polo-like protein kinase, putative 0.0163 0.0664 0.108
Entamoeba histolytica geranylgeranyl pyrophosphate synthase, putative 0.0191 0.0784 0.1278
Mycobacterium ulcerans heat shock protein 90 0.0057 0.0213 0.0643
Mycobacterium tuberculosis Probable transcriptional regulatory protein (probably LuxR/UhpA-family) 0.054 0.2267 0.226
Brugia malayi ATP-dependent DNA helicase, RecQ family protein 0.0007 0.0001 0.0002
Echinococcus multilocularis neuropeptide Y receptor 0.0031 0.0103 0.0168
Echinococcus granulosus mothers against decapentaplegic 5 0.0011 0.0017 0.0028
Brugia malayi calpain family protein 1 0.0045 0.0162 0.0461
Giardia lamblia Kinase, AGC PKA 0.0049 0.018 0.0295
Schistosoma mansoni hypothetical protein 0.0285 0.1182 0.1935
Treponema pallidum 4'-phosphopantetheinyl transferase 0.0016 0.0039 0.0131
Loa Loa (eye worm) ICD-1 protein 0.0024 0.0075 0.0213
Brugia malayi Muscle positioning protein 4 0.001 0.0016 0.0044
Brugia malayi SET domain containing protein 0.0008 0.0007 0.0019
Loa Loa (eye worm) TK/FER protein kinase 0.001 0.0014 0.004
Echinococcus granulosus transcription factor btf3 0.0024 0.0075 0.0122
Schistosoma mansoni chromobox protein-related (chromobox 1) (heterochromatin 1) 0.0008 0.0005 0.0008
Entamoeba histolytica PH domain containing protein kinase, putative 0.0053 0.0196 0.0314
Trichomonas vaginalis AGC family protein kinase 0.0077 0.0297 0.0478
Loa Loa (eye worm) hypothetical protein 0.0031 0.0103 0.0292
Brugia malayi Valyl-tRNA synthetase 0.0008 0.0005 0.0014
Brugia malayi GTP-binding regulatory protein Gs alpha-S chain, putative 0.0061 0.0229 0.0651
Loa Loa (eye worm) hypothetical protein 0.0031 0.0103 0.0292
Onchocerca volvulus 0.001 0.0014 0.0072
Loa Loa (eye worm) hypothetical protein 0.0265 0.1098 0.3125
Brugia malayi SH2 domain containing protein 0.001 0.0014 0.004
Brugia malayi Protein kinase domain containing protein 0.001 0.0014 0.004
Echinococcus multilocularis alpha 1A adrenergic receptor 0.0031 0.0103 0.0168
Schistosoma mansoni serine/threonine-protein kinase 0.0053 0.0196 0.0321
Trypanosoma cruzi PAB1-binding protein , putative 0.0018 0.0046 0.0068
Schistosoma mansoni smad 0.0011 0.0017 0.0028
Brugia malayi neuropeptide F receptor 0.0031 0.0103 0.0292
Onchocerca volvulus 0.001 0.0014 0.0072
Echinococcus granulosus Serine:threonine protein kinase PLK4 0.0078 0.0304 0.0498
Brugia malayi Isocitrate dehydrogenase 0.0011 0.0018 0.0051
Plasmodium vivax endoplasmin, putative 0.0061 0.0229 0.0703
Trichomonas vaginalis heat shock protein, putative 0.0035 0.0121 0.019
Trypanosoma cruzi calpain-like cysteine peptidase, putative 0.0013 0.0028 0.0038
Mycobacterium ulcerans geranylgeranyl pyrophosphate synthase 0.0758 0.3193 1
Loa Loa (eye worm) hypothetical protein 0.0041 0.0146 0.0415
Loa Loa (eye worm) TK/FER protein kinase 0.001 0.0014 0.004
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.0013 0.0028 0.0038
Echinococcus granulosus dnaJ subfamily B 0.0285 0.1182 0.1935
Entamoeba histolytica protein kinase, putative 0.0008 0.0005 0.0001
Plasmodium falciparum protein kinase, putative 0.0008 0.0005 0.0012
Trypanosoma brucei Heat shock protein 83, putative 0.0061 0.0229 0.0368
Toxoplasma gondii DNA topoisomerase 2, putative 0.0009 0.0008 0.0025
Schistosoma mansoni cpg binding protein 0.002 0.0056 0.0092
Brugia malayi MH2 domain containing protein 0.0011 0.0017 0.0048
Trypanosoma cruzi polyprenyl synthase, putative 0.0191 0.0784 0.1278
Echinococcus granulosus roundabout 2 0.0021 0.0058 0.0096
Onchocerca volvulus Heterochromatin protein 1 homolog 0.0029 0.0096 0.0719
Entamoeba histolytica hypothetical protein, conserved 0.1444 0.6107 1
Loa Loa (eye worm) hypothetical protein 0.0084 0.0329 0.0936
Schistosoma mansoni opsin-like receptor 0.0031 0.0103 0.0168
Brugia malayi CXXC zinc finger family protein 0.002 0.0056 0.016
Brugia malayi Nuclear hormone receptor family member nhr-40 0.0156 0.0634 0.1804
Schistosoma mansoni neuropeptide receptor 0.0031 0.0103 0.0168
Brugia malayi MH1 domain containing protein 0.0011 0.0017 0.0048
Schistosoma mansoni family C2 unassigned peptidase (C02 family) 0.0047 0.0172 0.0281
Onchocerca volvulus Steroid hormone receptor family member cnr14 homolog 0.0156 0.0634 0.4995
Chlamydia trachomatis geranylgeranyl pyrophosphate synthase 0.0191 0.0784 0.7011
Schistosoma mansoni serine/threonine protein kinase 0.0218 0.09 0.1473
Trypanosoma cruzi heat shock protein 90, putative 0.0052 0.0192 0.0307
Echinococcus multilocularis ATP dependent DNA helicase PIF1 0.1444 0.6107 1
Onchocerca volvulus Netrin receptor homolog 0.0009 0.0009 0.0033
Echinococcus granulosus smad 0.0011 0.0017 0.0028
Schistosoma mansoni tyrosine kinase 0.0059 0.0221 0.0362
Brugia malayi Nuclear hormone receptor-like 1 0.0082 0.0321 0.0915
Echinococcus multilocularis g protein coupled receptor 0.0031 0.0103 0.0168
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0074 0.0284 0.0465
Schistosoma mansoni histamine-responsive GPCR (AAF21638) 0.0031 0.0103 0.0168
Brugia malayi Polyprenyl synthetase family protein 0.0191 0.0784 0.2231
Trichomonas vaginalis cat eye syndrome critical region protein 2, cscr2, putative 0.0029 0.0094 0.0146
Entamoeba histolytica phosphofructokinase, putative 0.0068 0.0261 0.0421
Echinococcus granulosus allatostatin A receptor 0.0031 0.0103 0.0168
Brugia malayi neuropeptide F receptor 0.0031 0.0103 0.0292
Echinococcus multilocularis ATP dependent DNA helicase Q5 0.0007 0.0001 0.0001
Entamoeba histolytica PH domain containing protein kinase, putative 0.0053 0.0196 0.0314
Echinococcus granulosus defective proboscis extension response 0.0017 0.0043 0.007
Brugia malayi Serotonin receptor 0.0031 0.0103 0.0292
Echinococcus granulosus ankyrin repeat and death domain containing protein 0.0007 0.0002 0.0004
Brugia malayi MH2 domain containing protein 0.0158 0.0643 0.183
Schistosoma mansoni cell adhesion molecule 0.0019 0.0052 0.0084
Loa Loa (eye worm) hypothetical protein 0.0009 0.0008 0.0024
Echinococcus granulosus ribosomal protein s6 kinase beta 1 0.0027 0.0084 0.0137
Loa Loa (eye worm) hypothetical protein 0.0031 0.0103 0.0292
Loa Loa (eye worm) hypothetical protein 0.0074 0.0284 0.0808
Brugia malayi nuclear receptor NHR-88 0.0156 0.0634 0.1804
Loa Loa (eye worm) hypothetical protein 0.0074 0.0284 0.0808
Loa Loa (eye worm) hypothetical protein 0.0304 0.1265 0.3598
Trichomonas vaginalis phosphofructokinase, putative 0.0068 0.0261 0.042
Echinococcus multilocularis protein patched 0.0029 0.0096 0.0158
Onchocerca volvulus 0.001 0.0014 0.0072
Echinococcus granulosus rhodopsin orphan GPCR 0.0031 0.0103 0.0168
Trichomonas vaginalis AGC family protein kinase 0.0077 0.0297 0.0478
Echinococcus multilocularis G protein coupled 5 hydroxytryptamine receptor 0.0031 0.0103 0.0168
Echinococcus granulosus activin receptor type 0.0008 0.0005 0.0007
Trypanosoma cruzi DNA topoisomerase II, putative 0.0009 0.0008 0.0006
Leishmania major heat shock protein 83-1 0.0061 0.0229 0.0368
Onchocerca volvulus 0.0031 0.0103 0.0775
Onchocerca volvulus 0.0074 0.0284 0.2215
Brugia malayi Immunoglobulin I-set domain containing protein 0.0017 0.0043 0.0122
Schistosoma mansoni family C54 unassigned peptidase (C54 family) 0.0041 0.0146 0.0239
Leishmania major isocitrate dehydrogenase [NADP], mitochondrial precursor, putative 0.0011 0.0018 0.0022
Echinococcus granulosus nuclear receptor nhr 48 0.0074 0.0284 0.0465
Brugia malayi phosphofructokinase 0.0068 0.0261 0.0744
Trichomonas vaginalis conserved hypothetical protein 0.0019 0.0053 0.0079
Echinococcus granulosus g protein linked acetylcholine receptor gar 2a 0.0031 0.0103 0.0168
Trichomonas vaginalis phosphofructokinase, putative 0.0018 0.005 0.0073
Echinococcus multilocularis dro:myosuppressin receptor 0.0031 0.0103 0.0168
Mycobacterium leprae Conserved hypothetical protein 0.0793 0.3343 1
Schistosoma mansoni family C54 unassigned peptidase (C54 family) 0.0041 0.0146 0.0239
Loa Loa (eye worm) nuclear Hormone Receptor family member 0.0156 0.0634 0.1804
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0012 0.0024 0.0032
Onchocerca volvulus 0.0008 0.0007 0.0015
Echinococcus multilocularis rhodopsin orphan GPCR 0.0031 0.0103 0.0168
Trypanosoma brucei recA bacterial DNA recombination protein, putative 0.0023 0.007 0.0107
Loa Loa (eye worm) CHromoDomain protein family member 0.0009 0.001 0.0028
Brugia malayi Nuclear hormone receptor-like 1 0.0156 0.0634 0.1804
Echinococcus multilocularis Immunoglobulin 0.0017 0.0043 0.007
Brugia malayi Uncoordinated protein 44 0.0007 0.0002 0.0006
Loa Loa (eye worm) hypothetical protein 0.0031 0.0103 0.0292
Schistosoma mansoni hypothetical protein 0.0007 0.0002 0.0004
Trichomonas vaginalis eukaryotic translation initiation factor 4E, putative 0.0046 0.0165 0.0263
Onchocerca volvulus 0.0008 0.0005 0.000000014274
Echinococcus granulosus nuclear factor of activated T cells 5 0.0037 0.013 0.0213
Loa Loa (eye worm) hypothetical protein 0.0031 0.0103 0.0292
Trypanosoma cruzi solanesyl-diphosphate synthase, putative 0.0191 0.0784 0.1278
Echinococcus granulosus X box binding protein 1 0.0201 0.0824 0.1349
Toxoplasma gondii heat shock protein HSP90 0.0061 0.0229 0.0716
Mycobacterium tuberculosis Probable polyprenyl-diphosphate synthase GrcC2 (polyprenyl pyrophosphate synthetase) 0.0191 0.0784 0.0776
Echinococcus multilocularis calpain 7 (C02 family) 0.0013 0.0028 0.0046
Trypanosoma cruzi cysteine peptidase, Clan CA, family C54, putative 0.0016 0.0039 0.0057
Brugia malayi Nuclear hormone receptor family member nhr-41 0.0156 0.0634 0.1804
Echinococcus multilocularis rhodopsin orphan GPCR 0.0031 0.0103 0.0168
Loa Loa (eye worm) hypothetical protein 0.001 0.0014 0.004
Echinococcus granulosus 6 phosphofructokinase 0.0068 0.0261 0.0428
Schistosoma mansoni tar DNA-binding protein 0.0044 0.0159 0.026
Echinococcus multilocularis tyrosine protein kinase Fps85D 0.001 0.0014 0.0023
Loa Loa (eye worm) hypothetical protein 0.0007 0.0003 0.0007
Loa Loa (eye worm) hypothetical protein 0.0031 0.0103 0.0292
Trypanosoma brucei mitogen activated protein kinase 4, putative 0.0054 0.0202 0.0323
Brugia malayi Hr1 repeat family protein 0.0027 0.0084 0.0239
Brugia malayi protein kinase C II. 0.0027 0.0084 0.0239
Trichomonas vaginalis geranylgeranyl pyrophosphate synthase, putative 0.0758 0.3193 0.5224
Schistosoma mansoni calpain-7 (C02 family) 0.0013 0.0028 0.0046
Trypanosoma cruzi malonyl-CoA decarboxylase, mitochondrial precursor, putative 0.0328 0.1363 0.2227
Echinococcus multilocularis FTZ F1 alpha 0.0156 0.0634 0.1038
Loa Loa (eye worm) hypothetical protein 0.0009 0.0009 0.0025
Schistosoma mansoni retinoblastoma-binding protein 4 (rbbp4) 0.0007 0.0003 0.0004
Echinococcus multilocularis tyrosine protein kinase Fyn 0.0012 0.0021 0.0035
Leishmania major heat shock protein 83-1 0.0061 0.0229 0.0368
Echinococcus multilocularis ATP dependent DNA helicase Q1 0.0007 0.0001 0.0001
Echinococcus granulosus FTZ F1 nuclear receptor protein 0.0156 0.0634 0.1038
Echinococcus granulosus epidermal growth factor receptor 0.0106 0.042 0.0688
Loa Loa (eye worm) hypothetical protein 0.0156 0.0634 0.1804
Brugia malayi isocitrate dehydrogenase 0.0011 0.0018 0.0051
Loa Loa (eye worm) TK/FER protein kinase 0.001 0.0014 0.004
Leishmania major heat shock protein 83-1 0.0061 0.0229 0.0368
Trypanosoma brucei cysteine peptidase, Clan CA, family C54, putative 0.0016 0.0039 0.0057
Echinococcus granulosus tyrosine protein kinase Srms 0.001 0.0014 0.0023
Trichomonas vaginalis chromobox protein, putative 0.0029 0.0096 0.0148
Echinococcus multilocularis TGF beta signal transducer SmadC 0.0011 0.0017 0.0028
Loa Loa (eye worm) TK/KIN16 protein kinase 0.0117 0.0471 0.1339
Loa Loa (eye worm) hypothetical protein 0.0074 0.0284 0.0808
Loa Loa (eye worm) CMGC/MAPK/ERK1 protein kinase 0.0054 0.0202 0.0574
Echinococcus granulosus ATP dependent DNA helicase Q1 0.0007 0.0001 0.0001
Trypanosoma brucei DNA topoisomerase ii 0.0009 0.0008 0.0006
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0012 0.0024 0.0032
Loa Loa (eye worm) hypothetical protein 0.0313 0.1302 0.3706
Echinococcus granulosus serine threonine protein kinase nrc 0.0049 0.018 0.0295
Chlamydia trachomatis holo [acyl-carrier protein] synthase 0.0016 0.0039 0.0273
Brugia malayi nuclear hormone receptor family member nhr-6 0.0074 0.0284 0.0808
Schistosoma mansoni transcription factor LCR-F1 0.0218 0.0897 0.1468
Schistosoma mansoni pyruvate dehydrogenase 0.0009 0.0008 0.0014
Schistosoma mansoni chromobox protein 0.0008 0.0005 0.0008
Entamoeba histolytica protein kinase, putative 0.0027 0.0084 0.013
Trichomonas vaginalis eukaryotic translation initiation factor 4E, putative 0.0046 0.0165 0.0263
Onchocerca volvulus Putative DNA topoisomerase 2, mitochondrial 0.0009 0.0008 0.0028
Echinococcus granulosus 7TM GPCR rhodopsin 0.0031 0.0103 0.0168
Trypanosoma brucei DNA repair and recombination helicase protein PIF7 0.1444 0.6107 1
Leishmania major heat shock protein 83-1 0.0061 0.0229 0.0368
Loa Loa (eye worm) MH2 domain-containing protein 0.0011 0.0017 0.0048
Echinococcus granulosus sex peptide receptor 0.0031 0.0103 0.0168
Plasmodium vivax holo-[acyl-carrier-protein] synthase, putative 0.0016 0.0039 0.0106
Trypanosoma cruzi solanesyl-diphosphate synthase, putative 0.0191 0.0784 0.1278
Leishmania major heat shock protein 83-1 0.0061 0.0229 0.0368
Trypanosoma brucei heat shock protein, putative 0.0061 0.0229 0.0368
Plasmodium vivax geranylgeranyl pyrophosphate synthase 0.0758 0.3193 1
Schistosoma mansoni smad1 5 8 and 0.0011 0.0017 0.0028
Echinococcus granulosus diuretic hormone 44 receptor GPRdih2 0.0032 0.0107 0.0175
Schistosoma mansoni nuclear hormone receptor nor-1/nor-2 0.0156 0.0634 0.1038
Echinococcus granulosus mitogen activated protein kinase 0.0054 0.0202 0.033
Entamoeba histolytica bifunctional short chain isoprenyl diphosphate synthase, putative 0.0191 0.0784 0.1278
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0156 0.0634 0.1038
Plasmodium falciparum ATP-dependent 6-phosphofructokinase 0.0018 0.005 0.0154
Schistosoma mansoni serine/threonine protein kinase 0.0027 0.0084 0.0137
Trypanosoma brucei antigen, putative 0.0013 0.0028 0.0038
Trypanosoma brucei calpain-like protein, putative 0.0013 0.0028 0.0038
Onchocerca volvulus 0.0031 0.0103 0.0775
Mycobacterium ulcerans glutaminase 0.0315 0.1309 0.4085
Schistosoma mansoni nuclear hormone receptor 0.0074 0.0284 0.0465
Echinococcus granulosus somatostatin receptor 0.0031 0.0103 0.0168
Loa Loa (eye worm) AGC/RSK/MSK protein kinase 0.0027 0.0084 0.0239
Echinococcus multilocularis roundabout 2 0.0021 0.0058 0.0096
Wolbachia endosymbiont of Brugia malayi replicative DNA helicase 0.0269 0.1115 0.3156
Loa Loa (eye worm) hypothetical protein 0.001 0.0016 0.0044
Trypanosoma cruzi heat shock protein 85, putative 0.0061 0.0229 0.0368
Trypanosoma brucei calpain-like protein, putative 0.0013 0.0028 0.0038
Plasmodium falciparum ADP-dependent DNA helicase RecQ 0.0015 0.0034 0.0104
Brugia malayi follicle stimulating hormone receptor 0.0031 0.0103 0.0292
Schistosoma mansoni neuropeptide receptor 0.0031 0.0103 0.0168
Loa Loa (eye worm) RecQ helicase 0.0017 0.0042 0.012
Plasmodium vivax basic transcription factor 3b, putative 0.0024 0.0075 0.0219
Trypanosoma brucei DNA topoisomerase II beta, putative 0.0009 0.0008 0.0006
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0031 0.0103 0.0168
Echinococcus multilocularis diuretic hormone 44 receptor GPRdih2 0.0032 0.0107 0.0175
Plasmodium vivax heat shock protein 86, putative 0.0061 0.0229 0.0703
Toxoplasma gondii histone lysine acetyltransferase GCN5-B 0.0029 0.0094 0.0293
Schistosoma mansoni vesicular amine transporter 0.0017 0.0043 0.007
Loa Loa (eye worm) CAMK/PIM protein kinase 0.0218 0.09 0.256
Brugia malayi Nuclear hormone receptor family member nhr-1 0.0156 0.0634 0.1804
Loa Loa (eye worm) hypothetical protein 0.0156 0.0634 0.1804
Loa Loa (eye worm) hypothetical protein 0.0082 0.0321 0.0915
Trypanosoma brucei kinesin, putative 0.0013 0.0028 0.0038
Entamoeba histolytica phosphofructokinase, putative 0.0068 0.0261 0.0421
Echinococcus multilocularis tyrosine protein kinase Fgr 0.0012 0.0021 0.0035
Loa Loa (eye worm) hypothetical protein 0.0029 0.0096 0.0274
Entamoeba histolytica SH2-protein kinase domain containing protein 0.0008 0.0005 0.0001
Schistosoma mansoni serine/threonine kinase 0.0027 0.0084 0.0137
Onchocerca volvulus DNA topoisomerase 2 homolog 0.0009 0.0008 0.0028
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0156 0.0634 0.1804
Giardia lamblia Histone acetyltransferase GCN5 0.0027 0.0084 0.0136
Echinococcus multilocularis rhodopsin orphan GPCR 0.0031 0.0103 0.0168
Schistosoma mansoni tyrosine kinase 0.0054 0.02 0.0327
Schistosoma mansoni Smad4 0.0011 0.0017 0.0028
Toxoplasma gondii ATP-dependent DNA helicase, RecQ family protein 0.0007 0.0001 0.000000000041835
Loa Loa (eye worm) hypothetical protein 0.0031 0.0103 0.0292
Entamoeba histolytica peptidase, C54 family 0.0016 0.0039 0.0057
Echinococcus granulosus tm gpcr rhodopsin 0.0031 0.0103 0.0168
Loa Loa (eye worm) variant SH3 domain-containing protein 0.0009 0.0009 0.0025
Loa Loa (eye worm) hypothetical protein 0.0019 0.0052 0.0147
Loa Loa (eye worm) hypothetical protein 0.0069 0.0264 0.0751
Brugia malayi nuclear receptor RXR 0.0074 0.0284 0.0808
Loa Loa (eye worm) TK/ALK protein kinase 0.0016 0.004 0.0114
Trichomonas vaginalis chromobox protein, putative 0.0029 0.0096 0.0148
Echinococcus multilocularis activin receptor type 0.0008 0.0005 0.0007
Loa Loa (eye worm) 6-phosphofructokinase 0.0068 0.0261 0.0744
Schistosoma mansoni atypical protein kinase C 0.0027 0.0084 0.0137
Loa Loa (eye worm) hypothetical protein 0.0031 0.0103 0.0292
Chlamydia trachomatis replicative DNA helicase 0.0269 0.1115 1
Schistosoma mansoni proto-oncogene tyrosine-protein kinase src 0.0012 0.0021 0.0035
Brugia malayi Dopamine receptor protein 1 0.0031 0.0103 0.0292
Schistosoma mansoni netrin receptor unc5 0.0009 0.0011 0.0018
Echinococcus multilocularis 0.0031 0.0104 0.0171
Echinococcus granulosus chromobox protein 1 0.0049 0.0177 0.0291
Echinococcus multilocularis retinoic acid receptor rxr beta a retinoic acid receptor rxr alpha a retinoic acid receptor rxr alpha 0.0074 0.0284 0.0465
Trypanosoma cruzi calpain-like cysteine peptidase, putative 0.0013 0.0028 0.0038
Loa Loa (eye worm) DEAH box polypeptide 35 0.0033 0.0112 0.032
Brugia malayi Unidentified vitellogenin-linked transcript protein 6, putative 0.0031 0.0103 0.0292
Loa Loa (eye worm) hypothetical protein 0.0017 0.0043 0.0122
Entamoeba histolytica hypothetical protein 0.0024 0.0075 0.0115
Brugia malayi 6-phosphofructokinase 0.0068 0.0261 0.0744
Loa Loa (eye worm) hypothetical protein 0.0056 0.0211 0.06
Loa Loa (eye worm) hypothetical protein 0.0008 0.0005 0.0014
Mycobacterium leprae conserved hypothetical protein 0.0016 0.0039 0.009
Brugia malayi hypothetical protein 0.001 0.0014 0.004
Schistosoma mansoni protein kinase 0.0008 0.0005 0.0007
Echinococcus multilocularis somatostatin receptor 0.0031 0.0103 0.0168
Plasmodium vivax octaprenyl pyrophosphate synthase, putative 0.0191 0.0784 0.2444
Echinococcus multilocularis protein kinase c epsilon type 0.0027 0.0084 0.0137
Brugia malayi calpain family protein 1 0.0045 0.0162 0.0461
Plasmodium falciparum DNA topoisomerase 2 0.0009 0.0008 0.0025
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0074 0.0284 0.0465
Wolbachia endosymbiont of Brugia malayi geranylgeranyl pyrophosphate synthase 0.0191 0.0784 0.2213
Loa Loa (eye worm) hypothetical protein 0.0074 0.0284 0.0808
Echinococcus granulosus dro:myosuppressin receptor 0.0031 0.0103 0.0168
Trichomonas vaginalis serine/threonine-protein kinase sgk, putative 0.0024 0.0072 0.0109
Toxoplasma gondii polyprenyl synthetase superfamily protein 0.0758 0.3193 1
Toxoplasma gondii eukaryotic initiation factor-4E, putative 0.0046 0.0165 0.0516
Loa Loa (eye worm) AGC/RSK/P70 protein kinase 0.0073 0.0281 0.0799
Schistosoma mansoni serine/threonine protein kinase 0.0163 0.0664 0.1087
Schistosoma mansoni tyrosine kinase 0.0106 0.042 0.0688
Trichomonas vaginalis phosphofructokinase, putative 0.0068 0.0261 0.042
Leishmania major polyprenyl synthase, putative 0.0191 0.0784 0.1278
Leishmania major heat shock protein 83-1 0.0061 0.0229 0.0368
Entamoeba histolytica calpain large subunit domain III containing protein 0.0013 0.0028 0.0038
Brugia malayi nuclear receptor subfamily 1, group D, member 1, putative 0.0074 0.0284 0.0808
Echinococcus granulosus death domain containing protein 0.0007 0.0002 0.0004
Echinococcus granulosus rhodopsin orphan GPCR 0.0031 0.0103 0.0168
Brugia malayi calpain 5 0.0013 0.0028 0.008
Echinococcus multilocularis hypothetical protein 0.0013 0.0028 0.0046
Echinococcus multilocularis prenyl (decaprenyl) diphosphate synthase 0.0191 0.0784 0.1284
Brugia malayi Serotonin/octopamine receptor family protein 7 0.0031 0.0103 0.0292
Echinococcus granulosus Peptidase C54 0.0041 0.0146 0.0239
Entamoeba histolytica protein kinase, putative 0.0077 0.0297 0.0479
Trichomonas vaginalis endoplasmin, putative 0.0044 0.0158 0.0251
Brugia malayi hypothetical protein 0.0074 0.0284 0.0808
Wolbachia endosymbiont of Brugia malayi malonyl-CoA decarboxylase 0.0834 0.3514 1
Loa Loa (eye worm) hypothetical protein 0.0027 0.0087 0.0247
Loa Loa (eye worm) polyprenyl synthetase 0.0758 0.3193 0.9085
Schistosoma mansoni hypothetical protein 0.0031 0.0103 0.0168
Echinococcus multilocularis Nuclear hormone receptor family member nhr 41 0.0156 0.0634 0.1038
Trichomonas vaginalis AGC family protein kinase 0.0077 0.0297 0.0478
Echinococcus multilocularis Pyruvate dehydrogenase (lipoamide) kinase 0.0009 0.0008 0.0014
Mycobacterium ulcerans putative regulatory protein 0.054 0.2267 0.7092
Schistosoma mansoni transcription factor btf3 0.0024 0.0075 0.0122
Loa Loa (eye worm) hypothetical protein 0.0074 0.0284 0.0808
Trichomonas vaginalis DNA helicase recq, putative 0.0009 0.0009 0.0007
Loa Loa (eye worm) acetyltransferase 0.0098 0.0389 0.1107
Loa Loa (eye worm) follicle stimulating hormone receptor 0.0031 0.0103 0.0292
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0031 0.0103 0.0168
Schistosoma mansoni trans-prenyltransferase 0.0191 0.0784 0.1284
Schistosoma mansoni glutaminase 0.0315 0.1309 0.2144
Leishmania major mitogen activated protein kinase 4, putative;with=GeneDB:LmxM19.1440 0.0054 0.0202 0.0323
Echinococcus multilocularis tyrosine protein kinase shark 0.001 0.0014 0.0023
Loa Loa (eye worm) helicase 0.0008 0.0005 0.0014
Trichomonas vaginalis geranylgeranyl diphosphate synthase, putative 0.0758 0.3193 0.5224
Echinococcus multilocularis dual specificity testis specific protein kinase 0.0008 0.0005 0.0007
Brugia malayi Protein kinase domain containing protein 0.001 0.0014 0.004
Echinococcus granulosus Ataxin 2 N terminaldomain containing protein 0.0008 0.0005 0.0008
Trichomonas vaginalis heat shock protein, putative 0.0052 0.0192 0.0306
Brugia malayi Serotonin receptor 0.0031 0.0103 0.0292
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0031 0.0103 0.0168
Echinococcus multilocularis Basic leucine zipper (bZIP) transcription 0.0218 0.0897 0.1468
Trypanosoma brucei heat shock protein 90, putative 0.0061 0.0229 0.0368
Schistosoma mansoni hypothetical protein 0.0106 0.0424 0.0694
Loa Loa (eye worm) TYRA-2 protein 0.0031 0.0103 0.0292
Brugia malayi Heterochromatin protein 1 0.0049 0.0177 0.0505
Echinococcus granulosus tyrosine kinase 0.001 0.0014 0.0023
Echinococcus granulosus serine:threonine protein kinase N2 0.0027 0.0084 0.0137
Loa Loa (eye worm) hypothetical protein 0.0011 0.0019 0.0054
Echinococcus multilocularis sex peptide receptor 0.0031 0.0103 0.0168
Entamoeba histolytica heat shock protein 90, putative 0.0061 0.0229 0.0368
Loa Loa (eye worm) nuclear hormone receptor family member nhr-41 0.0156 0.0634 0.1804
Loa Loa (eye worm) hypothetical protein 0.0021 0.0062 0.0176
Brugia malayi Endoplasmin precursor 0.0061 0.0229 0.0652
Brugia malayi photoreceptor-specific nuclear receptor 0.0156 0.0634 0.1804
Brugia malayi Death domain containing protein 0.0007 0.0002 0.0006
Echinococcus granulosus hypothetical protein 0.0031 0.0103 0.0168
Loa Loa (eye worm) hypothetical protein 0.0027 0.0084 0.0239
Trypanosoma cruzi Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase, putative 0.0009 0.0008 0.0006
Echinococcus granulosus peptide allatostatin:somatostatin 0.0031 0.0103 0.0168
Loa Loa (eye worm) hypothetical protein 0.0031 0.0103 0.0292
Echinococcus multilocularis G-protein coupled receptor, putative 0.0031 0.0103 0.0168
Schistosoma mansoni serine/threonine protein kinase 0.0027 0.0084 0.0137
Schistosoma mansoni peptide (allatostatin)-like receptor 0.0031 0.0103 0.0168
Onchocerca volvulus 0.001 0.0014 0.0072
Echinococcus granulosus calpain 7 C02 family 0.0013 0.0028 0.0046
Onchocerca volvulus DNA topoisomerase 2 homolog 0.0009 0.0008 0.0028
Brugia malayi CHE-14 protein 0.0029 0.0096 0.0274
Echinococcus granulosus fmrfamide receptor 0.0031 0.0103 0.0168
Echinococcus multilocularis neuropeptides capa receptor 0.0031 0.0103 0.0168
Echinococcus granulosus proto oncogene tyrosine protein kinase LCK 0.0012 0.0021 0.0035
Plasmodium falciparum heat shock protein 90, putative 0.0035 0.0121 0.0378
Schistosoma mansoni opsin-like receptor 0.0031 0.0103 0.0168
Trichomonas vaginalis CMGC family protein kinase 0.0054 0.0202 0.0322
Loa Loa (eye worm) TAR-binding protein 0.0044 0.0159 0.0452
Entamoeba histolytica protein kinase, putative 0.0073 0.0281 0.0453
Trypanosoma cruzi calpain-like cysteine peptidase, putative 0.0013 0.0028 0.0038
Echinococcus multilocularis neuropeptide s receptor 0.0031 0.0103 0.0168
Echinococcus multilocularis Ribosomal protein S6 kinase beta 2 0.0027 0.0084 0.0137
Loa Loa (eye worm) hypothetical protein 0.0074 0.0284 0.0808
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0061 0.0229 0.0375
Loa Loa (eye worm) pigment dispersing factor receptor c 0.0101 0.0399 0.1136
Loa Loa (eye worm) calpain 5 0.0013 0.0028 0.008
Plasmodium falciparum basic transcription factor 3b, putative 0.0024 0.0075 0.0232
Brugia malayi translation initiation factor 4E 0.0046 0.0165 0.0471
Schistosoma mansoni endoplasmin 0.0061 0.0229 0.0375
Trichomonas vaginalis conserved hypothetical protein 0.0019 0.0053 0.0079
Trypanosoma cruzi mitochondrial DNA topoisomerase II, putative 0.0009 0.0008 0.0006
Echinococcus granulosus serotonin receptor 0.0031 0.0103 0.0168
Echinococcus granulosus epidermal growth factor receptor 0.0059 0.0221 0.0362
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0156 0.0634 0.1804
Echinococcus granulosus NDR protein kinase 0.0027 0.0084 0.0137
Schistosoma mansoni FTZ-F1 nuclear receptor-like protein 0.0156 0.0634 0.1038
Loa Loa (eye worm) MH2 domain-containing protein 0.0158 0.0643 0.183
Trichomonas vaginalis AGC family protein kinase 0.0077 0.0297 0.0478
Brugia malayi Nuclear hormone receptor family member nhr-14 0.0156 0.0634 0.1804
Leishmania major heat shock protein 83-1 0.0061 0.0229 0.0368
Schistosoma mansoni hypothetical protein 0.0031 0.0103 0.0168
Mycobacterium tuberculosis Probable geranylgeranyl pyrophosphate synthetase IdsA2 (ggppsase) (GGPP synthetase) (geranylgeranyl diphosphate synthase) 0.0758 0.3193 0.3187
Brugia malayi MH2 domain containing protein 0.0011 0.0017 0.0048
Echinococcus multilocularis NADP dependent isocitrate dehydrogenase 0.0011 0.0018 0.0029
Loa Loa (eye worm) hypothetical protein 0.0031 0.0103 0.0292
Schistosoma mansoni hypothetical protein 0.0011 0.0019 0.0031
Loa Loa (eye worm) TK/FER protein kinase 0.001 0.0014 0.004
Echinococcus multilocularis tyrosine protein kinase ABL1 0.001 0.0014 0.0023
Onchocerca volvulus 0.001 0.0016 0.0084
Loa Loa (eye worm) hypothetical protein 0.0156 0.0634 0.1804
Echinococcus multilocularis sterol regulatory element binding protein 0.0029 0.0096 0.0158
Echinococcus granulosus rhodopsin orphan GPCR 0.0031 0.0103 0.0168
Trichomonas vaginalis conserved hypothetical protein 0.0024 0.0075 0.0114
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0061 0.0229 0.0375
Trichomonas vaginalis CAMK family protein kinase 0.0066 0.0251 0.0404
Schistosoma mansoni blooms syndrome DNA helicase 0.0013 0.0027 0.0045
Trichomonas vaginalis DNA helicase recq, putative 0.0017 0.0042 0.0061
Schistosoma mansoni serine/threonine protein kinase 0.0116 0.0465 0.0761
Loa Loa (eye worm) hypothetical protein 0.0045 0.0162 0.0461
Echinococcus multilocularis tyrosine protein kinase Src64B 0.0012 0.0021 0.0035
Mycobacterium ulcerans two component transcriptional regulatory protein DevR 0.054 0.2267 0.7092
Loa Loa (eye worm) hypothetical protein 0.0156 0.0634 0.1804
Loa Loa (eye worm) 6-phosphofructokinase 0.0068 0.0261 0.0744
Loa Loa (eye worm) hypothetical protein 0.0031 0.0103 0.0292
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0156 0.0634 0.1804
Mycobacterium tuberculosis RecA protein (recombinase A) [contains: endonuclease PI-MTUI (MTU RecA intein)]. 0.2166 0.9176 0.9175
Echinococcus granulosus Glutaredoxin protein 5 0.0046 0.0168 0.0275
Echinococcus granulosus tyrosine kinase|tyrosine protein kinase Fyn 0.001 0.0014 0.0023
Trypanosoma brucei heat shock protein, putative 0.0061 0.0229 0.0368
Echinococcus multilocularis neuropeptide FF receptor 2 0.0031 0.0103 0.0168
Trichomonas vaginalis conserved hypothetical protein 0.0027 0.0087 0.0134
Leishmania major AUT2/APG4/ATG4 cysteine peptidase, putative 0.0041 0.0146 0.0231
Trypanosoma cruzi cysteine peptidase, Clan CA, family C2, putative 0.0013 0.0028 0.0038
Echinococcus multilocularis isocitrate dehydrogenase 0.0011 0.0018 0.0029
Schistosoma mansoni hypothetical protein 0.001 0.0016 0.0025
Echinococcus multilocularis L aminoadipate semialdehyde 0.0056 0.0211 0.0345
Loa Loa (eye worm) hypothetical protein 0.0008 0.0005 0.0014
Echinococcus multilocularis Serine:threonine protein kinase PLK4 0.0078 0.0304 0.0498
Echinococcus granulosus Chromobox protein 3 0.0008 0.0005 0.0008
Loa Loa (eye worm) nuclear hormone receptor family member nhr-49 0.0156 0.0634 0.1804
Echinococcus granulosus geranylgeranyl pyrophosphate synthase 0.0191 0.0784 0.1284
Loa Loa (eye worm) hypothetical protein 0.0031 0.0103 0.0292
Echinococcus granulosus protein kinase c iota type 0.0027 0.0084 0.0137
Onchocerca volvulus Heat shock protein 75 kDa, mitochondrial homolog 0.004 0.0143 0.1092
Echinococcus granulosus c src tyrosine kinase 0.0012 0.0021 0.0035
Loa Loa (eye worm) hypothetical protein 0.0074 0.0284 0.0808
Schistosoma mansoni serine/threonine protein kinase 0.0027 0.0084 0.0137
Onchocerca volvulus 0.0031 0.0103 0.0775
Brugia malayi hypothetical protein 0.0082 0.0321 0.0915
Plasmodium falciparum RAC-beta serine/threonine protein kinase 0.0049 0.018 0.0563
Schistosoma mansoni calpain (C02 family) 0.0013 0.0028 0.0046
Brugia malayi Probable DNA topoisomerase II 0.0009 0.0008 0.0024
Schistosoma mansoni tyrosine kinase 0.0012 0.0021 0.0035
Echinococcus granulosus pyroglutamylated rfamide peptide receptor 0.0031 0.0103 0.0168
Echinococcus multilocularis MAM 0.0011 0.0019 0.0031
Echinococcus multilocularis tyrosine protein kinase Blk 0.001 0.0014 0.0023
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.001 0.0014 0.0015
Schistosoma mansoni peptide (FMRFamide/neurokinin-3)-like receptor 0.0031 0.0103 0.0168
Echinococcus multilocularis protein kinase c iota type 0.0027 0.0084 0.0137
Echinococcus multilocularis sodium:potassium dependent atpase beta subunit 0.0046 0.0168 0.0275
Leishmania major DNA topoisomerase ii 0.0009 0.0008 0.0006
Mycobacterium tuberculosis holo-[acyl-carrier protein] synthase AcpS (holo-ACP synthase) (CoA:APO-[ACP]pantetheinephosphotransferase) (CoA:APO-[acyl-carrie 0.0016 0.0039 0.003
Trypanosoma cruzi polyprenyl synthase, putative 0.0191 0.0784 0.1278
Plasmodium falciparum ataxin-2 like protein, putative 0.0018 0.0046 0.0142
Echinococcus granulosus calpain 0.0013 0.0028 0.0046
Echinococcus granulosus calpain A 0.0047 0.0172 0.0281
Trypanosoma cruzi Eukaryotic translation initiation factor 4E-1 0.0046 0.0165 0.0264
Schistosoma mansoni biogenic amine (5HT) receptor 0.0031 0.0103 0.0168
Leishmania major ATP-dependent phosphofructokinase 0.0068 0.0261 0.0421
Loa Loa (eye worm) hypothetical protein 0.0031 0.0103 0.0292
Loa Loa (eye worm) TK/FER protein kinase 0.001 0.0014 0.004
Trypanosoma brucei farnesyl pyrophosphate synthase 0.0758 0.3193 0.5225
Echinococcus multilocularis Peptidase C54 0.0041 0.0146 0.0239
Onchocerca volvulus Huntingtin homolog 0.0085 0.0334 0.261
Brugia malayi Nuclear hormone receptor family member nhr-31 0.0156 0.0634 0.1804
Schistosoma mansoni retinoid-x-receptor (RXR) 0.0082 0.0321 0.0526
Echinococcus multilocularis insulin receptor 0.0037 0.0127 0.0209
Brugia malayi G protein-coupled receptor 0.0031 0.0103 0.0292
Plasmodium falciparum heat shock protein 90, putative 0.023 0.0949 0.297
Plasmodium vivax histone acetyltransferase GCN5, putative 0.0029 0.0094 0.028
Trypanosoma cruzi isocitrate dehydrogenase [NADP], mitochondrial precursor, putative 0.0011 0.0018 0.0022
Schistosoma mansoni peptide (FMRFamide/somatostatin)-like receptor 0.0031 0.0103 0.0168
Onchocerca volvulus 0.001 0.0016 0.0084
Mycobacterium leprae PROBABLE CHAPERONE PROTEIN HTPG (HEAT SHOCK PROTEIN) (HSP90 FAMILY PROTEIN) (HIGH TEMPERATURE PROTEIN G) 0.0057 0.0213 0.0614
Loa Loa (eye worm) nuclear hormone receptor family member nhr-40 0.0156 0.0634 0.1804
Schistosoma mansoni chromobox protein 0.0008 0.0005 0.0008
Loa Loa (eye worm) hypothetical protein 0.0031 0.0103 0.0292
Schistosoma mansoni tyrosine kinase 0.0037 0.0127 0.0209
Echinococcus multilocularis NADP dependent isocitrate dehydrogenase 0.0011 0.0018 0.0029
Echinococcus multilocularis tyrosine protein kinase Fyn 0.0012 0.0021 0.0035
Schistosoma mansoni nuclear hormone receptor superfamily protein-related 0.0074 0.0284 0.0465
Schistosoma mansoni tyrosine kinase 0.0012 0.0021 0.0035
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0156 0.0634 0.1038
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0156 0.0634 0.1804
Brugia malayi Variant SH3 domain containing protein 0.0009 0.0009 0.0025
Leishmania major lipophosphoglycan biosynthetic protein, putative,heat shock protein 90, putative,glucose regulated protein 94, putative 0.0057 0.0213 0.0342
Schistosoma mansoni DNA topoisomerase II 0.0009 0.0008 0.0014
Echinococcus multilocularis biogenic amine (5HT) receptor 0.0031 0.0103 0.0168
Plasmodium vivax hypothetical protein, conserved 0.0008 0.0005 0.00000000003793
Echinococcus granulosus neuropeptide Y receptor 0.0031 0.0103 0.0168
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0031 0.0103 0.0168
Echinococcus multilocularis dnaJ subfamily B 0.0285 0.1182 0.1935
Toxoplasma gondii isocitrate dehydrogenase 0.0011 0.0018 0.0055
Trypanosoma cruzi farnesyl pyrophosphate synthase 0.0758 0.3193 0.5225
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.001 0.0015 0.0017
Echinococcus granulosus histone acetyltransferase KAT2B 0.0096 0.0377 0.0618
Schistosoma mansoni nuclear hormone receptor 0.0074 0.0284 0.0465
Brugia malayi Protein cec-1. 0.0008 0.0005 0.0014
Schistosoma mansoni histone-lysine n-methyltransferase suv9 0.0008 0.0007 0.0011
Loa Loa (eye worm) hypothetical protein 0.0031 0.0103 0.0292
Wolbachia endosymbiont of Brugia malayi heat shock protein 90 0.0057 0.0213 0.0584
Echinococcus multilocularis heat shock protein 75 kDa, mitochondrial 0.004 0.0143 0.0233
Brugia malayi hypothetical protein 0.0011 0.0019 0.0055
Schistosoma mansoni tyrosine kinase 0.001 0.0014 0.0023
Leishmania major basic transcription factor 3a, putative 0.0024 0.0075 0.0115
Brugia malayi SRC-1 0.0012 0.0021 0.006
Trypanosoma cruzi heat shock protein 90, putative 0.0025 0.0079 0.0122
Treponema pallidum diphosphate--fructose-6-phosphate 1-phosphotransferase 0.0018 0.005 0.0178
Toxoplasma gondii 4'-phosphopantetheinyl transferase superfamily protein 0.0016 0.0039 0.0119
Schistosoma mansoni nuclear receptor nhr-48 0.0074 0.0284 0.0465
Loa Loa (eye worm) geranylgeranyl pyrophosphate synthetase 0.0191 0.0784 0.2231
Leishmania major developmentally regulated phosphoprotein-like protein 0.0009 0.0008 0.0006
Trypanosoma cruzi isocitrate dehydrogenase, putative 0.0011 0.0018 0.0022
Entamoeba histolytica hypothetical protein 0.0218 0.0897 0.1462
Giardia lamblia Grp94/Hsp90 0.0057 0.0213 0.0348
Loa Loa (eye worm) TK/FER protein kinase 0.001 0.0014 0.004
Echinococcus granulosus g protein coupled receptor 0.0031 0.0103 0.0168
Loa Loa (eye worm) hypothetical protein 0.0032 0.0105 0.0299
Brugia malayi tailless protein 0.0074 0.0284 0.0808
Loa Loa (eye worm) unidentified vitellogenin-linked transcript protein 6 0.0031 0.0103 0.0292
Echinococcus multilocularis chromobox protein 2 0.0008 0.0005 0.0008
Trypanosoma cruzi rac serine-threonine kinase, putative 0.0053 0.0196 0.0314
Loa Loa (eye worm) ATP-dependent DNA helicase 0.0007 0.0001 0.0002
Trypanosoma brucei cysteine peptidase, Clan CA, family C2, putative 0.0013 0.0028 0.0038
Plasmodium vivax hypothetical protein, conserved 0.0009 0.0008 0.0011
Echinococcus multilocularis eukaryotic translation initiation factor 4E 0.0046 0.0165 0.0271
Entamoeba histolytica hypothetical protein 0.0218 0.0897 0.1462
Echinococcus multilocularis tyrosine protein kinase Srms 0.001 0.0014 0.0023
Brugia malayi putative neuropeptide receptor NPR1 0.0031 0.0103 0.0292
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0061 0.0229 0.0375
Trypanosoma brucei AUT2/APG4/ATG4 cysteine peptidase, putative 0.0041 0.0146 0.0231
Loa Loa (eye worm) melatonin receptor type 1A 0.0031 0.0103 0.0292
Echinococcus multilocularis Niemann Pick C1 protein 0.0069 0.0263 0.043
Schistosoma mansoni coup transcription factor 0.0156 0.0634 0.1038
Trypanosoma cruzi heat shock protein 85, putative 0.0052 0.0192 0.0307
Plasmodium falciparum holo-[acyl-carrier-protein] synthase, putative 0.0016 0.0039 0.0119
Giardia lamblia Rrm3p helicase 0.1444 0.6107 1
Leishmania major farnesyl pyrophosphate synthase 0.0758 0.3193 0.5225
Onchocerca volvulus 0.0031 0.0103 0.0775
Toxoplasma gondii isocitrate dehydrogenase 0.0011 0.0018 0.0055
Trichomonas vaginalis geranylgeranyl pyrophosphate synthase, putative 0.0758 0.3193 0.5224
Toxoplasma gondii 'chromo' (CHRromatin Organization MOdifier) domain-containing protein 0.0008 0.0005 0.0014
Trypanosoma cruzi polo-like protein kinase, putative 0.0163 0.0664 0.108
Echinococcus granulosus thyrotropin releasing hormone receptor 0.0031 0.0103 0.0168
Echinococcus multilocularis tachykinin peptides receptor 99D 0.0031 0.0103 0.0168
Schistosoma mansoni chromobox protein 0.0049 0.0177 0.0291
Brugia malayi G-protein-linked acetylcholine receptor protein 2, putative 0.0031 0.0103 0.0292
Trichomonas vaginalis heat shock protein, putative 0.0044 0.0158 0.0251
Trypanosoma brucei heat shock protein, putative 0.0061 0.0229 0.0368
Entamoeba histolytica peptidase, C54 family 0.0016 0.0039 0.0057
Echinococcus granulosus netrin receptor unc 5 0.0009 0.0011 0.0018
Schistosoma mansoni endoplasmin 0.0061 0.0229 0.0375
Loa Loa (eye worm) TK/FER protein kinase 0.001 0.0014 0.004
Echinococcus multilocularis rhodopsin orphan GPCR 0.0031 0.0103 0.0168
Giardia lamblia Kinase, CMGC MAPK 0.0054 0.0202 0.0329
Schistosoma mansoni nephrin 0.0018 0.005 0.0081
Echinococcus multilocularis epidermal growth factor receptor 0.0059 0.0221 0.0362
Schistosoma mansoni ankyrin 23/unc44 0.0007 0.0002 0.0004
Echinococcus multilocularis NADP dependent isocitrate dehydrogenase 0.0011 0.0018 0.0029
Schistosoma mansoni hypothetical protein 0.0032 0.0107 0.0175
Loa Loa (eye worm) nuclear hormone receptor 0.0074 0.0284 0.0808
Plasmodium falciparum heterochromatin protein 1 0.0008 0.0005 0.0014
Plasmodium falciparum isocitrate dehydrogenase [NADP], mitochondrial 0.0011 0.0018 0.0055
Trypanosoma brucei heat shock protein 90, putative 0.0061 0.0229 0.0368
Echinococcus granulosus tyrosine protein kinase ABL1 0.001 0.0014 0.0023
Entamoeba histolytica hypothetical protein 0.0008 0.0005 0.0001
Leishmania major heat shock protein 83-1 0.0061 0.0229 0.0368
Mycobacterium ulcerans polyprenyl diphosphate synthetase, GrcC1 0.0191 0.0784 0.2436
Loa Loa (eye worm) TK/FER protein kinase 0.001 0.0014 0.004
Onchocerca volvulus Nuclear receptor subfamily 6 group A member 1 homolog 0.0074 0.0284 0.2215
Echinococcus multilocularis rac serine:threonine kinase 0.0053 0.0196 0.0321
Schistosoma mansoni autophagin-1 (C54 family) 0.0041 0.0146 0.0239
Leishmania major heat shock protein 83-1 0.0061 0.0229 0.0368
Schistosoma mansoni serine/threonine protein kinase 0.0027 0.0084 0.0137
Echinococcus multilocularis G protein coupled receptor 139 0.0216 0.089 0.1457
Echinococcus multilocularis serine:threonine protein kinase PLK1 0.0163 0.0664 0.1087
Loa Loa (eye worm) AGC/RSK/RSK protein kinase 0.0027 0.0084 0.0239
Schistosoma mansoni steroid hormone receptor ad4bp 0.0156 0.0634 0.1038
Echinococcus granulosus heat shock protein 90 0.0061 0.0229 0.0375
Entamoeba histolytica transcription factor BTF3, putative 0.0024 0.0075 0.0115
Echinococcus granulosus nuclear receptor subfamily 1 group D 0.0082 0.0321 0.0526
Giardia lamblia Heat shock protein HSP 90-alpha 0.0052 0.0192 0.0313
Loa Loa (eye worm) transcription factor SMAD2 0.0158 0.0643 0.183
Schistosoma mansoni tar DNA-binding protein 0.0044 0.0159 0.026
Schistosoma mansoni tyrosine kinase 0.0012 0.0021 0.0035
Schistosoma mansoni eukaryotic translation initiation factor 4e 0.0046 0.0165 0.0271
Plasmodium vivax 6-phosphofructokinase, putative 0.0018 0.005 0.014
Trypanosoma brucei protein kinase, putative 0.0054 0.0202 0.0323
Loa Loa (eye worm) hypothetical protein 0.0074 0.0284 0.0808
Schistosoma mansoni 6-phosphofructokinase 0.0068 0.0261 0.0428
Echinococcus granulosus cadherin EGF LAG seven pass G type receptor 0.0032 0.0107 0.0175
Brugia malayi hypothetical protein 0.0031 0.0103 0.0292
Echinococcus granulosus neuropeptides capa receptor 0.0031 0.0103 0.0168
Schistosoma mansoni tyrosine kinase 0.0054 0.02 0.0327
Trichomonas vaginalis Clan CA, family C54, ATG4-like cysteine peptidase 0.0041 0.0146 0.0231
Schistosoma mansoni hypothetical protein 0.0106 0.0424 0.0694
Trypanosoma cruzi ATP-dependent DEAD/H DNA helicase recQ, putative 0.0009 0.0009 0.0008
Schistosoma mansoni chromobox protein-related (chromobox 1) (heterochromatin 1) 0.0008 0.0005 0.0008
Echinococcus granulosus ribosomal protein S6 kinase alpha 3 0.0027 0.0084 0.0137
Loa Loa (eye worm) hypothetical protein 0.0069 0.0263 0.0747
Schistosoma mansoni hypothetical protein 0.0069 0.0264 0.0432
Schistosoma mansoni family C2 unassigned peptidase (C02 family) 0.0045 0.0162 0.0265
Giardia lamblia Farnesyl diphosphate synthase 0.0758 0.3193 0.5228
Schistosoma mansoni protein kinase 0.0008 0.0005 0.0007
Schistosoma mansoni Neurotrimin precursor (hNT) 0.0017 0.0043 0.007
Brugia malayi Protein kinase domain containing protein 0.001 0.0014 0.004
Trypanosoma cruzi DNA repair and recombination helicase protein PIF7, putative 0.1444 0.6107 1
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.0013 0.0028 0.0038
Trichomonas vaginalis Clan CA, family C54, ATG4-like cysteine peptidase 0.0041 0.0146 0.0231
Schistosoma mansoni biogenic amine (octopamine/dopamine) receptor 0.0031 0.0103 0.0168
Loa Loa (eye worm) calpain family protein 1 0.0045 0.0162 0.0461
Trichomonas vaginalis CAMK family protein kinase 0.0163 0.0664 0.108
Loa Loa (eye worm) neuropeptide F receptor 0.0031 0.0103 0.0292
Echinococcus granulosus histone acetyltransferase KAT2B 0.0029 0.0094 0.0154
Schistosoma mansoni TGF-beta signal transducer Smad2 0.0011 0.0017 0.0028
Echinococcus granulosus neuropeptides capa receptor 0.0031 0.0103 0.0168
Trypanosoma cruzi solanesyl-diphosphate synthase 0.0191 0.0784 0.1278
Echinococcus granulosus heat shock protein 90 0.0052 0.0192 0.0314
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0031 0.0103 0.0168
Echinococcus granulosus neuropeptide s receptor 0.0031 0.0103 0.0168
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0156 0.0634 0.1804
Plasmodium falciparum histone acetyltransferase GCN5 0.0027 0.0084 0.0261
Plasmodium vivax ataxin-2 like protein, putative 0.0018 0.0046 0.0128
Echinococcus multilocularis g protein coupled receptor 0.0031 0.0103 0.0168
Trypanosoma cruzi ATP-dependent 6-phosphofructokinase, glycosomal 0.0068 0.0261 0.0421
Schistosoma mansoni hypothetical protein 0.0032 0.0107 0.0175
Schistosoma mansoni hypothetical protein 0.0031 0.0103 0.0168
Schistosoma mansoni ancient conserved domain protein 2 (cyclin m2) 0.0031 0.0103 0.0168
Echinococcus granulosus tm gpcr rhodopsin 0.0031 0.0103 0.0168
Trichomonas vaginalis Clan CA, family C54, ATG4-like cysteine peptidase 0.0041 0.0146 0.0231
Entamoeba histolytica peptidase, C54 family 0.0016 0.0039 0.0057
Trichomonas vaginalis CAMK family protein kinase 0.0163 0.0664 0.108
Echinococcus multilocularis orexin receptor type 2 0.0031 0.0103 0.0168
Onchocerca volvulus Neuropeptide F receptor homolog 0.0031 0.0103 0.0775
Trichomonas vaginalis conserved hypothetical protein 0.001 0.0015 0.0017
Echinococcus multilocularis Nuclear hormone receptor HR96 0.0074 0.0284 0.0465
Echinococcus multilocularis ribosomal protein s6 kinase beta 1 0.0027 0.0084 0.0137
Loa Loa (eye worm) latrophilin receptor protein 2 0.0032 0.0107 0.0304
Echinococcus granulosus melanoma receptor tyrosine protein kinase 0.0059 0.0221 0.0362
Echinococcus granulosus Nuclear hormone receptor HR96 0.0074 0.0284 0.0465
Brugia malayi Probable ATP-dependent helicase DHX35 0.0033 0.0112 0.032
Echinococcus granulosus neuropeptide receptor 0.0216 0.089 0.1457
Schistosoma mansoni amine GPCR 0.0031 0.0103 0.0168
Brugia malayi Smad1 0.0011 0.0017 0.0048
Echinococcus multilocularis rhodopsin orphan GPCR 0.0031 0.0103 0.0168
Trypanosoma cruzi calpain-like cysteine peptidase, putative 0.0013 0.0028 0.0038
Schistosoma mansoni tyrosine kinase 0.0037 0.0127 0.0209
Brugia malayi hypothetical protein 0.0008 0.0005 0.0015
Echinococcus multilocularis Smad4 0.0011 0.0017 0.0028
Echinococcus multilocularis tyrosine kinase 0.001 0.0014 0.0023
Echinococcus granulosus serine/threonine protein kinase 0.0053 0.0196 0.0321
Loa Loa (eye worm) hypothetical protein 0.0031 0.0103 0.0292
Loa Loa (eye worm) DOMON domain-containing protein 0.001 0.0016 0.0044
Trypanosoma cruzi heat shock protein 85, putative 0.0061 0.0229 0.0368
Mycobacterium tuberculosis Possible nitrate/nitrite response transcriptional regulatory protein NarL 0.054 0.2267 0.226
Onchocerca volvulus 0.0031 0.0103 0.0775
Leishmania major calpain, putative,cysteine peptidase, Clan CA, family C2, putative 0.0013 0.0028 0.0038
Loa Loa (eye worm) heterochromatin protein 1 0.0049 0.0177 0.0505
Trypanosoma cruzi mitogen-activated protein kinase 11, putative 0.0054 0.0202 0.0323
Onchocerca volvulus Phospholipase A2 homolog 0.0064 0.0244 0.1894
Trichomonas vaginalis chromobox protein, putative 0.0049 0.0177 0.0283
Echinococcus granulosus decaprenyl diphosphate synthase subunit 1 0.0191 0.0784 0.1284
Loa Loa (eye worm) hypothetical protein 0.0082 0.0321 0.0915
Trypanosoma brucei PAB1-binding protein , putative 0.0018 0.0046 0.0068
Echinococcus multilocularis serotonin receptor 0.0031 0.0103 0.0168
Schistosoma mansoni hypothetical protein 0.0064 0.0243 0.0397
Mycobacterium tuberculosis Probable transcriptional regulatory protein (LuxR-family) 0.054 0.2267 0.226
Echinococcus granulosus survival motor neuron protein 1 0.0313 0.1302 0.2132
Loa Loa (eye worm) hypothetical protein 0.0834 0.3514 1
Schistosoma mansoni RAR-like nuclear receptor 0.0156 0.0634 0.1038
Echinococcus granulosus expressed conserved protein 0.0064 0.0245 0.0401
Loa Loa (eye worm) hypothetical protein 0.0031 0.0103 0.0292
Echinococcus granulosus insulin receptor 0.0037 0.0127 0.0209
Onchocerca volvulus 0.0056 0.0211 0.1635
Echinococcus granulosus proto oncogene serine:threonine protein kinase 0.0218 0.09 0.1473
Loa Loa (eye worm) hypothetical protein 0.0031 0.0103 0.0292
Trichomonas vaginalis conserved hypothetical protein 0.0024 0.0075 0.0114
Trichomonas vaginalis phosphofructokinase, putative 0.0068 0.0261 0.042
Schistosoma mansoni hypothetical protein 0.0218 0.0897 0.1468
Loa Loa (eye worm) hypothetical protein 0.0031 0.0103 0.0292
Loa Loa (eye worm) CAMK/PIM protein kinase 0.0218 0.09 0.256
Schistosoma mansoni thyroid hormone receptor 0.0156 0.0634 0.1038
Brugia malayi Dopamine receptor protein 1, putative (partial) 0.0031 0.0103 0.0292
Trypanosoma brucei Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase, putative 0.0009 0.0008 0.0006
Trichomonas vaginalis conserved hypothetical protein 0.0024 0.0075 0.0114
Leishmania major eukaryotic translation initiation factor eIF-4E, putative 0.0046 0.0165 0.0264
Brugia malayi acetyltransferase, GNAT family protein 0.0098 0.0389 0.1107
Echinococcus multilocularis expressed conserved protein 0.0064 0.0245 0.0401
Brugia malayi G-protein coupled receptor 0.0031 0.0103 0.0292
Trichomonas vaginalis CMGC family protein kinase 0.0054 0.0202 0.0322
Echinococcus granulosus growth hormone secretagogue receptor type 1 0.0031 0.0103 0.0168
Schistosoma mansoni neuropeptide F-like receptor 0.0031 0.0103 0.0168
Schistosoma mansoni tyrosine kinase 0.0059 0.0221 0.0362
Trichomonas vaginalis sensor histidine kinase, putative 0.0009 0.0008 0.0006
Brugia malayi aminoadipate-semialdehyde dehydrogenase-phosphopantetheinyl transferase 0.0056 0.0211 0.06
Trypanosoma brucei rac serine-threonine kinase, putative 0.0077 0.0297 0.0479
Wolbachia endosymbiont of Brugia malayi geranylgeranyl pyrophosphate synthase 0.0191 0.0784 0.2213
Brugia malayi Phospholipase A2 family protein 0.0064 0.0244 0.0693
Brugia malayi ATP-dependent DNA helicase, RecQ family protein 0.0007 0.0001 0.0002
Schistosoma mansoni tar DNA-binding protein 0.0044 0.0159 0.026
Loa Loa (eye worm) hypothetical protein 0.0085 0.0334 0.095
Leishmania major kinesin, putative 0.0013 0.0028 0.0038
Brugia malayi MH1 domain containing protein 0.0011 0.0017 0.0048
Echinococcus multilocularis Pyruvate dehydrogenase (lipoamide) kinase 0.0009 0.0008 0.0014
Echinococcus granulosus neuroglian 0.0018 0.005 0.0081
Schistosoma mansoni serine/threonine protein kinase 0.0027 0.0084 0.0137
Schistosoma mansoni neuropeptide f receptor 76f 0.0031 0.0103 0.0168
Trypanosoma brucei heat shock protein, putative 0.0061 0.0229 0.0368
Echinococcus multilocularis geranylgeranyl pyrophosphate synthase 0.0191 0.0784 0.1284
Leishmania major heat shock protein 83-1 0.0061 0.0229 0.0368
Entamoeba histolytica geranylgeranyl pyrophosphate synthetase, putative 0.0191 0.0784 0.1278
Schistosoma mansoni 6-phosphofructokinase 0.0068 0.0261 0.0428
Entamoeba histolytica hypothetical protein 0.0218 0.0897 0.1462
Loa Loa (eye worm) hypothetical protein 0.0031 0.0103 0.0292
Trichomonas vaginalis Clan CA, family C54, ATG4-like cysteine peptidase 0.0041 0.0146 0.0231
Trichomonas vaginalis phosphofructokinase, putative 0.0018 0.005 0.0073
Brugia malayi Protein kinase domain containing protein 0.0116 0.0465 0.1322
Plasmodium vivax 6-phosphofructokinase, putative 0.0018 0.005 0.014
Schistosoma mansoni nuclear receptor 2DBD-gamma 0.0156 0.0634 0.1038
Echinococcus multilocularis calpain 0.0013 0.0028 0.0046
Entamoeba histolytica peptidase, C54 family 0.0041 0.0146 0.0231
Trypanosoma cruzi transcription factor btf3, putative 0.0024 0.0075 0.0115
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0031 0.0103 0.0168
Mycobacterium ulcerans polyprenyl synthetase IdsB 0.0191 0.0784 0.2436
Echinococcus multilocularis neuropeptide receptor 0.0031 0.0103 0.0168
Echinococcus multilocularis family C2 unassigned peptidase (C02 family) 0.0047 0.0172 0.0281
Trypanosoma cruzi cysteine peptidase, Clan CA, family C2, putative 0.0013 0.0028 0.0038
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0061 0.0229 0.0375
Echinococcus multilocularis calpain 5 0.0013 0.0028 0.0046
Schistosoma mansoni tyrosine kinase 0.01 0.0397 0.0649
Trypanosoma brucei transcription factor BTF3, putative 0.0024 0.0075 0.0115
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0031 0.0103 0.0168
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0012 0.0024 0.0032
Toxoplasma gondii 'chromo' (CHRromatin Organization MOdifier) domain-containing protein 0.0008 0.0005 0.0014
Brugia malayi Calcitonin receptor-like protein seb-1 0.0101 0.0399 0.1136
Schistosoma mansoni alpha-1 adrenergic receptor 0.0031 0.0103 0.0168
Brugia malayi Protein kinase domain containing protein 0.0016 0.004 0.0114
Schistosoma mansoni hypothetical protein 0.0032 0.0107 0.0175
Echinococcus multilocularis hepatocyte nuclear factor 4 alpha 0.0156 0.0634 0.1038
Trypanosoma brucei malonyl-CoA decarboxylase, mitochondrial precursor, putative 0.0328 0.1363 0.2227
Trypanosoma brucei DNA repair and recombination helicase protein PIF6 0.1444 0.6107 1
Loa Loa (eye worm) PLK/PLK1 protein kinase 0.0163 0.0664 0.1889
Leishmania major PIF1 helicase-like protein, putative,DNA repair and recombination protein, mitochondrial precursor, putative 0.1444 0.6107 1
Toxoplasma gondii AGC kinase 0.0073 0.0281 0.0878
Wolbachia endosymbiont of Brugia malayi 4'-phosphopantetheinyl transferase 0.0016 0.0039 0.0086
Loa Loa (eye worm) hypothetical protein 0.0156 0.0634 0.1804
Schistosoma mansoni heat shock protein 0.0061 0.0229 0.0375
Schistosoma mansoni tyrosine kinase 0.0009 0.0008 0.0013
Onchocerca volvulus 0.001 0.0016 0.0084
Echinococcus multilocularis GPCR, family 2 0.0032 0.0107 0.0175
Trypanosoma brucei polo-like protein kinase 0.0163 0.0664 0.108
Loa Loa (eye worm) hypothetical protein 0.0008 0.0005 0.0015
Loa Loa (eye worm) MH1 domain-containing protein 0.0011 0.0017 0.0048
Entamoeba histolytica SH2-protein kinase domain containing protein 0.001 0.0014 0.0016
Loa Loa (eye worm) TK/FER protein kinase 0.001 0.0014 0.004
Echinococcus multilocularis chromobox protein 1 0.0049 0.0177 0.0291
Schistosoma mansoni chromodomain helicase DNA binding protein 0.0009 0.001 0.0016
Trypanosoma cruzi DNA topoisomerase II, putative 0.0009 0.0008 0.0006
Echinococcus multilocularis calpain A 0.0047 0.0172 0.0281
Echinococcus multilocularis tar DNA binding protein 0.0044 0.0159 0.026
Schistosoma mansoni heat shock protein 0.004 0.0143 0.0233
Schistosoma mansoni muscarinic acetylcholine (GAR) receptor 0.0031 0.0103 0.0168
Mycobacterium leprae PROBABLE 6-PHOSPHOFRUCTOKINASE PFKA (PHOSPHOHEXOKINASE) (PHOSPHOFRUCTOKINASE) 0.0068 0.0261 0.0758
Mycobacterium tuberculosis Probable 6-phosphofructokinase PfkA (phosphohexokinase) (phosphofructokinase) 0.0068 0.0261 0.0253
Loa Loa (eye worm) hypothetical protein 0.0031 0.0103 0.0292
Loa Loa (eye worm) calpain family protein 1 0.0032 0.0105 0.0299
Trichomonas vaginalis DNA helicase recq1, putative 0.0017 0.0042 0.0061
Echinococcus multilocularis chromodomain helicase DNA binding protein 1 0.0008 0.0005 0.0008
Echinococcus multilocularis neuropeptide receptor A26 0.0031 0.0103 0.0168
Trypanosoma brucei ATP-dependent 6-phosphofructokinase, glycosomal 0.0068 0.0261 0.0421
Trichomonas vaginalis sensory transduction histidine kinase bacterial, putative 0.0009 0.0008 0.0006
Trypanosoma cruzi heat shock protein 90, putative 0.0061 0.0229 0.0368
Echinococcus multilocularis proto oncogene serine:threonine protein kinase 0.0218 0.09 0.1473
Onchocerca volvulus Dopamine\/Ecdysteroid receptor homolog 0.0031 0.0103 0.0775
Echinococcus granulosus tyrosine protein kinase Fyn 0.0012 0.0021 0.0035
Entamoeba histolytica chromodomain-helicase-DNA-binding protein, putative 0.0008 0.0005 0.0001
Echinococcus granulosus 3'partial|tyrosine protein kinase Fgr 0.0012 0.0021 0.0035
Trichomonas vaginalis conserved hypothetical protein 0.0029 0.0096 0.015
Loa Loa (eye worm) TK/EGFR protein kinase 0.0106 0.042 0.1195
Treponema pallidum recombinase A 0.0075 0.0291 0.1221
Schistosoma mansoni peptide (allatostatin/somatostatin)-like receptor 0.0031 0.0103 0.0168
Trypanosoma brucei RNA helicase, putative 0.026 0.1077 0.1757
Schistosoma mansoni serine/threonine protein kinase 0.0027 0.0084 0.0137
Echinococcus multilocularis rhodopsin orphan GPCR 0.0031 0.0103 0.0168
Treponema pallidum diphosphate--fructose-6-phosphate 1-phosphotransferase 0.0068 0.0261 0.1095
Brugia malayi Immunoglobulin I-set domain containing protein 0.0117 0.0471 0.1339
Loa Loa (eye worm) AGC/AKT protein kinase 0.0077 0.0297 0.0844
Trypanosoma brucei developmentally regulated phosphoprotein 0.0009 0.0008 0.0006
Trichomonas vaginalis phosphofructokinase, putative 0.0018 0.005 0.0073
Echinococcus granulosus neuropeptide receptor 0.0031 0.0103 0.0168
Loa Loa (eye worm) hypothetical protein 0.0031 0.0103 0.0292
Trypanosoma brucei calpain-like protein, putative 0.0013 0.0028 0.0038
Trichomonas vaginalis CAMK family protein kinase 0.0163 0.0664 0.108
Brugia malayi serine/threonine-protein kinase plk-2 0.0163 0.0664 0.1889
Echinococcus granulosus g-protein coupled receptor 0.0031 0.0103 0.0168
Brugia malayi geranylgeranyl pyrophosphate synthetase 0.0191 0.0784 0.2231
Trichomonas vaginalis CAMK family protein kinase 0.0163 0.0664 0.108
Loa Loa (eye worm) hypothetical protein 0.0031 0.0103 0.0292
Loa Loa (eye worm) SRC-1 0.0012 0.0021 0.006
Trichomonas vaginalis phosphofructokinase, putative 0.0018 0.005 0.0073
Echinococcus granulosus tyrosine kinase 0.001 0.0014 0.0023
Plasmodium falciparum ATP-dependent 6-phosphofructokinase 0.0018 0.005 0.0154
Echinococcus granulosus mitogen activated protein kinase 3 0.0054 0.0202 0.033
Echinococcus granulosus chromobox protein 2 0.0008 0.0005 0.0008
Brugia malayi Nuclear hormone receptor-like 1 0.0082 0.0321 0.0915
Toxoplasma gondii heat shock protein 75, putative 0.004 0.0143 0.0445
Echinococcus granulosus G protein coupled receptor 139 0.0031 0.0103 0.0168
Treponema pallidum heat shock protein 90 0.0057 0.0213 0.0887
Brugia malayi latrophilin 2 splice variant baaae 0.0069 0.0264 0.0751
Trichomonas vaginalis AGC family protein kinase 0.0027 0.0084 0.0129
Loa Loa (eye worm) steroid hormone receptor 0.0156 0.0634 0.1804
Trypanosoma cruzi DNA repair and recombination helicase protein PIF7, putative 0.1444 0.6107 1
Loa Loa (eye worm) hypothetical protein 0.0031 0.0103 0.0292
Trichomonas vaginalis mismatch repair protein Mlh1C (mutL homolog) 0.0009 0.0008 0.0006
Trichomonas vaginalis phosphofructokinase, putative 0.0018 0.005 0.0073
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0012 0.0024 0.0032
Mycobacterium leprae PROBABLE POLYPRENYL-DIPHOSPHATE SYNTHASE GRCC1 (POLYPRENYL PYROPHOSPHATE SYNTHETASE) 0.0191 0.0784 0.2326
Trypanosoma cruzi farnesyl pyrophosphate synthase, putative 0.0758 0.3193 0.5225
Loa Loa (eye worm) G-protein-linked acetylcholine receptor protein 2 0.0031 0.0103 0.0292
Trypanosoma cruzi DNA repair protein, putative 0.0023 0.007 0.0107
Echinococcus multilocularis neuropeptides capa receptor 0.0031 0.0103 0.0168
Loa Loa (eye worm) hypothetical protein 0.0074 0.0284 0.0808
Loa Loa (eye worm) TK/INSR protein kinase 0.0037 0.0127 0.0362
Echinococcus multilocularis serine:threonine protein kinase N2 0.0027 0.0084 0.0137
Trichomonas vaginalis CAMK family protein kinase 0.0066 0.0251 0.0404
Loa Loa (eye worm) hypothetical protein 0.0074 0.0284 0.0808
Echinococcus multilocularis FTZ F1 nuclear receptor protein 0.0156 0.0634 0.1038
Echinococcus granulosus Immunoglobulin 0.0017 0.0043 0.007
Echinococcus granulosus protein kinase c epsilon type 0.0027 0.0084 0.0137
Brugia malayi RNA binding protein 0.0044 0.0159 0.0452
Echinococcus granulosus tyrosine protein kinase Fyn 0.0012 0.0021 0.0035
Echinococcus multilocularis farnesyl pyrophosphate synthase 0.0758 0.3193 0.5228
Echinococcus multilocularis Glutaredoxin protein 5 0.0046 0.0168 0.0275
Schistosoma mansoni retinoid-x-receptor (RXR) 0.0156 0.0634 0.1038
Echinococcus multilocularis ankyrin repeat and death domain containing protein 0.0007 0.0002 0.0004
Trichomonas vaginalis CAMK family protein kinase 0.0163 0.0664 0.108
Brugia malayi ORL1-like opioid receptor 0.0031 0.0103 0.0292
Loa Loa (eye worm) hypothetical protein 0.0156 0.0634 0.1804
Echinococcus granulosus Ribosomal protein S6 kinase beta 2 0.0027 0.0084 0.0137
Echinococcus granulosus cpg binding protein 0.0021 0.0061 0.01
Echinococcus multilocularis ecdysone induced protein 78C 0.0156 0.0634 0.1038
Brugia malayi protein-tyrosine kinase 0.001 0.0014 0.004
Entamoeba histolytica hypothetical protein 0.0218 0.0897 0.1462
Loa Loa (eye worm) phosphofructokinase 0.0068 0.0261 0.0744
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0008 0.0005 0.000000000019816
Brugia malayi M-phase phosphoprotein, mpp8 0.0008 0.0005 0.0014
Onchocerca volvulus 0.0031 0.0103 0.0775
Trypanosoma brucei DNA topoisomerase II alpha, putative 0.0009 0.0008 0.0006
Schistosoma mansoni adenoreceptor 0.0031 0.0103 0.0168
Trichomonas vaginalis AGC family protein kinase 0.0077 0.0297 0.0478
Brugia malayi calcium-independent alpha-latrotoxin receptor 2, putative 0.0032 0.0107 0.0304
Loa Loa (eye worm) hypothetical protein 0.0009 0.0008 0.0024
Echinococcus granulosus TGF beta signal transducer SmadC 0.0011 0.0017 0.0028
Schistosoma mansoni vav2 0.0009 0.0009 0.0014
Leishmania major phosphopantetheinyl transferase-like protein 0.0016 0.0039 0.0056
Echinococcus multilocularis X box binding protein 1 0.0201 0.0824 0.1349
Echinococcus granulosus MAM 0.0011 0.0019 0.0031
Echinococcus multilocularis cpg binding protein 0.0021 0.0061 0.01
Leishmania major heat shock protein 83-1 0.0061 0.0229 0.0368
Echinococcus granulosus bloom syndrome protein 0.0017 0.0042 0.0069
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0008 0.0005 0.000000000019816
Treponema pallidum octaprenyl-diphosphate synthase 0.0191 0.0784 0.3358
Trichomonas vaginalis chromobox protein, putative 0.0049 0.0177 0.0283
Brugia malayi nuclear hormone receptor family member odr-7 0.0074 0.0284 0.0808
Loa Loa (eye worm) hypothetical protein 0.0031 0.0103 0.0292
Trypanosoma brucei calpain-like protein, putative 0.0013 0.0028 0.0038
Trichomonas vaginalis CMGC family protein kinase 0.0054 0.0202 0.0322
Schistosoma mansoni biogenic amine receptor 0.0031 0.0103 0.0168
Echinococcus multilocularis g protein linked acetylcholine receptor gar 2a 0.0031 0.0103 0.0168
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0156 0.0634 0.1038
Brugia malayi 6-phosphofructokinase 0.0068 0.0261 0.0744
Loa Loa (eye worm) 5-hydroxytryptamine 2C receptor 0.0031 0.0103 0.0292
Trichomonas vaginalis sensory transduction histidine kinase, putative 0.0009 0.0008 0.0006
Onchocerca volvulus 0.0031 0.0103 0.0775
Echinococcus multilocularis nuclear receptor subfamily 1 group D 0.0082 0.0321 0.0526
Echinococcus multilocularis tyrosine protein kinase Fyn 0.0012 0.0021 0.0035
Trypanosoma cruzi kinesin, putative 0.0013 0.0028 0.0038
Brugia malayi hypothetical protein 0.0031 0.0103 0.0292
Schistosoma mansoni growth hormone secretagogue receptor 0.0031 0.0103 0.0168
Schistosoma mansoni hypothetical protein 0.0028 0.0092 0.015
Loa Loa (eye worm) nuclear hormone receptor family member nhr-1 0.0156 0.0634 0.1804
Echinococcus granulosus g protein linked acetylcholine receptor gar 2a 0.0031 0.0103 0.0168
Loa Loa (eye worm) AGC/PKC/ETA protein kinase 0.0027 0.0084 0.0239
Echinococcus multilocularis 6 phosphofructokinase 0.0068 0.0261 0.0428
Echinococcus multilocularis decaprenyl diphosphate synthase subunit 1 0.0191 0.0784 0.1284
Brugia malayi Nuclear hormone receptor family member nhr-49 0.0156 0.0634 0.1804
Loa Loa (eye worm) RNA binding protein 0.0044 0.0159 0.0452
Leishmania major solanesyl-diphosphate synthase, putative 0.0191 0.0784 0.1278
Echinococcus multilocularis rhodopsin orphan GPCR 0.0031 0.0103 0.0168
Giardia lamblia Heat shock protein HSP 90-alpha 0.0061 0.0229 0.0374
Onchocerca volvulus 0.001 0.0014 0.0072
Echinococcus granulosus Ankyrin 0.0007 0.0003 0.0004
Brugia malayi small heat shock protein 0.0265 0.1098 0.3125
Brugia malayi nuclear receptor NHR-67 0.0074 0.0284 0.0808
Echinococcus multilocularis rhodopsin orphan GPCR 0.0031 0.0103 0.0168
Trichomonas vaginalis CAMK family protein kinase 0.0163 0.0664 0.108
Echinococcus multilocularis netrin receptor unc 5 0.0009 0.0011 0.0018
Schistosoma mansoni serine/threonine-protein kinase 0.0053 0.0196 0.0321
Toxoplasma gondii histone lysine acetyltransferase GCN5-A 0.0029 0.0094 0.0293
Onchocerca volvulus 0.0074 0.0284 0.2215
Brugia malayi Protein kinase domain containing protein 0.0077 0.0297 0.0844
Trypanosoma cruzi Eukaryotic translation initiation factor 4E-1 0.0046 0.0165 0.0264
Schistosoma mansoni hepatocyte nuclear factor 4-alpha (hnf-4-alpha) 0.0074 0.0284 0.0465
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0008 0.0005 0.000000000019816
Trichomonas vaginalis Clan CA, family C54, ATG4-like cysteine peptidase 0.0041 0.0146 0.0231
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0061 0.0229 0.0375
Brugia malayi Iron-sulfur cluster assembly accessory protein 0.0064 0.0243 0.0691
Schistosoma mansoni protein kinase 0.0008 0.0005 0.0007
Trichomonas vaginalis AGC family protein kinase 0.0077 0.0297 0.0478
Echinococcus granulosus heat shock protein heat shock protein 90 alpha 0.0052 0.0192 0.0314
Loa Loa (eye worm) immunoglobulin I-set domain-containing protein 0.0007 0.0002 0.0006
Echinococcus multilocularis protein dispatched 1 0.0034 0.0114 0.0187
Onchocerca volvulus 0.0064 0.0243 0.1887
Loa Loa (eye worm) hypothetical protein 0.001 0.0016 0.0044
Brugia malayi kinase, mitochondrial precursor 0.0009 0.0008 0.0024
Trypanosoma cruzi PAB1-binding protein , putative 0.0018 0.0046 0.0068
Echinococcus granulosus biogenic amine 5HT receptor 0.0031 0.0103 0.0168
Echinococcus multilocularis geminin 0.0106 0.0424 0.0694
Brugia malayi hypothetical protein 0.0031 0.0103 0.0292
Mycobacterium tuberculosis Possible polyprenyl synthetase IdsB (polyprenyl transferase) (polyprenyl diphosphate synthase) 0.0191 0.0784 0.0776
Echinococcus multilocularis chromodomain helicase DNA binding protein 4 0.0009 0.001 0.0016
Loa Loa (eye worm) G-protein coupled receptor 0.0031 0.0103 0.0292
Brugia malayi CHD4 protein 0.0009 0.001 0.0028
Leishmania major protein kinase, putative,polo-like protein kinase, putative 0.0163 0.0664 0.108
Echinococcus multilocularis tyrosine protein kinase lyn lyn a protein tyrosine kinase lymphocyte specific protein tyrosine kinase 0.0012 0.0021 0.0035
Plasmodium falciparum octaprenyl pyrophosphate synthase 0.0191 0.0784 0.2455
Echinococcus multilocularis Niemann Pick C1 protein 0.0098 0.0388 0.0635
Brugia malayi Tachykinin-like peptides receptor 99D 0.0031 0.0103 0.0292
Brugia malayi p70 ribosomal S6 kinase beta 0.0073 0.0281 0.0799
Treponema pallidum replicative DNA helicase (dnaB) 0.0269 0.1115 0.479
Brugia malayi Serine/threonine-protein kinase Pim-3 0.0218 0.09 0.256
Onchocerca volvulus 0.0031 0.0103 0.0775
Echinococcus granulosus Basic leucine zipper bZIP transcription 0.0218 0.0897 0.1468
Echinococcus granulosus Protein kinase C brain isozyme 0.0027 0.0084 0.0137
Trichomonas vaginalis bromodomain-containing protein, putative 0.0029 0.0094 0.0146
Loa Loa (eye worm) hypothetical protein 0.0031 0.0103 0.0292
Trypanosoma cruzi Heat shock protein 83, putative 0.0061 0.0229 0.0368
Schistosoma mansoni zinc finger protein 0.0074 0.0284 0.0465
Echinococcus multilocularis tyrosine protein kinase Btk29A 0.0102 0.0404 0.0661
Schistosoma mansoni hypothetical protein 0.0032 0.0107 0.0175
Echinococcus multilocularis gcn5proteinral control of amino acid synthesis 0.0098 0.0389 0.0637
Trypanosoma brucei hypothetical protein, conserved 0.0016 0.0039 0.0056
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0061 0.0229 0.0375
Brugia malayi Hsp90 protein 0.004 0.0143 0.0406
Plasmodium vivax calpain, putative 0.0013 0.0028 0.0072
Loa Loa (eye worm) hypothetical protein 0.0082 0.0321 0.0915
Trichomonas vaginalis heat shock protein, putative 0.0057 0.0213 0.0341
Loa Loa (eye worm) CXXC zinc finger family protein 0.002 0.0056 0.016
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0031 0.0103 0.0168
Mycobacterium ulcerans two component transcriptional regulator 0.054 0.2267 0.7092
Trypanosoma cruzi transcription factor btf3, putative 0.0024 0.0075 0.0115
Echinococcus multilocularis Nuclear hormone receptor HR96 0.0074 0.0284 0.0465
Toxoplasma gondii phosphofructokinase domain-containing protein 0.0018 0.005 0.0154
Mycobacterium ulcerans nitrate/nitrite response regulator protein NarL 0.054 0.2267 0.7092
Echinococcus multilocularis neuroglian 0.0018 0.005 0.0081
Echinococcus multilocularis fmrfamide receptor 0.0031 0.0103 0.0168
Echinococcus granulosus hepatocyte nuclear factor 4 alpha 0.0156 0.0634 0.1038
Trypanosoma cruzi AUT2/APG4/ATG4 cysteine peptidase, putative 0.0016 0.0039 0.0057
Brugia malayi Protein kinase domain containing protein 0.001 0.0014 0.0041
Trichomonas vaginalis 6-phosphofructokinase, putative 0.0018 0.005 0.0073
Echinococcus multilocularis isocitrate dehydrogenase 2 (NADP+) 0.0011 0.0018 0.0029
Echinococcus multilocularis fmrfamide receptor 0.0031 0.0103 0.0168
Schistosoma mansoni farnesyl pyrophosphate synthase 0.0758 0.3193 0.5228
Echinococcus granulosus alpha 1A adrenergic receptor 0.0031 0.0103 0.0168
Loa Loa (eye worm) hypothetical protein 0.0031 0.0103 0.0292
Echinococcus multilocularis COUP TF:Svp nuclear hormone receptor 0.0156 0.0634 0.1038
Wolbachia endosymbiont of Brugia malayi recombinase A 0.0075 0.0291 0.0805
Schistosoma mansoni serine/threonine protein kinase 0.0027 0.0084 0.0137
Entamoeba histolytica 90 kDa heat shock protein, putative 0.004 0.0143 0.0226
Trypanosoma cruzi Protein kinase B 0.0053 0.0196 0.0314
Onchocerca volvulus 0.0032 0.0105 0.0795
Brugia malayi Fibronectin type III domain containing protein 0.0017 0.0043 0.0122
Entamoeba histolytica hypothetical protein 0.0016 0.0039 0.0056
Onchocerca volvulus 0.0031 0.0103 0.0775
Schistosoma mansoni calpain-7 (C02 family) 0.0013 0.0028 0.0046
Echinococcus multilocularis neuropeptide Y receptor 0.0031 0.0103 0.0168
Entamoeba histolytica chromodomain-helicase-DNA-binding protein, putative 0.0008 0.0005 0.0001
Trichomonas vaginalis phosphofructokinase, putative 0.0018 0.005 0.0073
Brugia malayi MAP kinase sur-1 0.0054 0.0202 0.0574
Echinococcus multilocularis heat shock protein 90 0.0052 0.0192 0.0314
Brugia malayi hypothetical protein 0.0017 0.0043 0.0122
Echinococcus multilocularis chromobox protein 1 0.0049 0.0177 0.0291

Activities

Activity type Activity value Assay description Source Reference
Ki (binding) = 95 nM Compound was tested for the displacement of [125I]-PYY (SK-N-MC) from Neuropeptide Y receptor type 1 in the membranes prepared from cells ChEMBL. 8632403
Ki (binding) = 95 nM Compound was tested for the displacement of [125I]-PYY (SK-N-MC) from Neuropeptide Y receptor type 1 in the membranes prepared from cells ChEMBL. 8632403
Ki (binding) = 988 nM Compound was tested for the displacement of [125I]-PYY(3-36) (SK-N-BE2) from Neuropeptide Y receptor type 2 in the membranes prepared from cells ChEMBL. 8632403
Ki (binding) = 988 nM Compound was tested for the displacement of [125I]-PYY(3-36) (SK-N-BE2) from Neuropeptide Y receptor type 2 in the membranes prepared from cells ChEMBL. 8632403

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
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External resources for this compound

Bibliographic References

1 literature reference was collected for this gene.

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