TDR Targets

Basic information

Technical information

Name: Unnamed compound
MW: 2374.76 | Formula: C102H176N34O29S
H donors: 33 H acceptors: 30 LogP: -9.45 Rotable bonds: 101
Rule of 5 violations (Lipinski): 4
SMILES: CSCC[C@@H](C(=O)O)NC(=O)[C@H]([C@H](O)C)NC(=O)[C@@H](NC(=O)[C@H]([C@H](CC)C)NC(=O)CNC(=O)[C@@H](NC(=O)[C@@H](NC(=O)[C@@H](NC(=O)[C@H](CC(=O)N)NC(=O)CNC(=O)[C@@H](NC(=O)[C@@H](NC(=O)[C@@H](NC(=O)[C@@H](NC(=O)[C@@H](NC(=O)[C@@H](NC(=O)[C@@H](NC(=O)[C@@H](NC(=O)[C@@H](NC(=O)CNC(=O)[C@@H]1CCCN1C(=O)[C@@H](NC(=O)CN)CC(C)C)CCCN=C(N)N)CC(C)C)CCC(=O)N)CCCN=C(N)N)CC(C)C)CC(C)C)CCC(=O)N)C)CO)Cc1nc[nH]c1)C)C)CC(C)C
InChi: 1S/C102H176N34O29S/c1-18-53(12)80(97(161)132-67(37-51(8)9)95(159)135-81(57(16)138)98(162)127-63(100(164)165)29-33-166-17)134-79(145)45-114-82(146)54(13)118-83(147)55(14)120-90(154)68(39-58-42-111-47-117-58)131-94(158)69(40-75(106)141)122-78(144)43-115-85(149)71(46-137)133-84(148)56(15)119-86(150)61(25-27-73(104)139)125-92(156)65(35-49(4)5)130-93(157)66(36-50(6)7)129-88(152)60(23-20-31-113-102(109)110)124-89(153)62(26-28-74(105)140)126-91(155)64(34-48(2)3)128-87(151)59(22-19-30-112-101(107)108)121-77(143)44-116-96(160)72-24-21-32-136(72)99(163)70(38-52(10)11)123-76(142)41-103/h42,47-57,59-72,80-81,137-138H,18-41,43-46,103H2,1-17H3,(H2,104,139)(H2,105,140)(H2,106,141)(H,111,117)(H,114,146)(H,115,149)(H,116,160)(H,118,147)(H,119,150)(H,120,154)(H,121,143)(H,122,144)(H,123,142)(H,124,153)(H,125,156)(H,126,155)(H,127,162)(H,128,151)(H,129,152)(H,130,157)(H,131,158)(H,132,161)(H,133,148)(H,134,145)(H,135,159)(H,164,165)(H4,107,108,112)(H4,109,110,113)/t53-,54-,55-,56-,57+,59-,60-,61-,62-,63-,64-,65-,66-,67-,68-,69-,70-,71-,72-,80-,81-/m0/s1
InChiKey: OLPNUFYZIDUHQF-YQSNPDSASA-N

Network

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Target Layer

Model Organisms

Species	Viewmode
Arabidopsis thaliana
Caenorhabditis elegans
Dictyostelium discoideum
Drosophila melanogaster
Escherichia coli
Homo sapiens
Mus musculus
Oryza sativa
Saccharomyces cerevisiae
Schmidtea mediterranea
Other organisms

TDR Pathogens:

Species	Viewmode
Brugia malayi
Chlamydia trachomatis
Echinococcus granulosus
Entamoeba histolytica
Echinococcus multilocularis
Giardia lamblia
Leishmania major
Loa Loa (eye worm)
Mycobacterium leprae
Mycobacterium tuberculosis
Mycobacterium ulcerans
Onchocerca volvulus
Plasmodium falciparum
Plasmodium vivax
Schistosoma mansoni
Trypanosoma brucei
Trypanosoma cruzi
Toxoplasma gondii
Treponema pallidum
Trichomonas vaginalis
Wolbachia endosymbiont of Brugia malayi

Other Pathogens:

Species	Viewmode
Babesia bovis
Candida albicans
Cryptosporidium hominis
Cryptosporidium parvum
Leishmania braziliensis
Leishmania donovani
Leishmania infantum
Leishmania mexicana
Neospora caninum
Plasmodium berghei
Plasmodium knowlesi
Plasmodium yoelii
Schistosoma japonicum
Trypanosoma brucei gambiense
Trypanosoma congolense
Theileria parva

Compound Layer

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Clustering layers

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Synonyms

No synonyms found for this compound

Targets

Known targets for this compound

Species	Target name	Source	Bibliographic reference
Homo sapiens	hypocretin (orexin) receptor 1	Starlite/ChEMBL	References
Homo sapiens	hypocretin (orexin) receptor 2	Starlite/ChEMBL	References

Predicted pathogen targets for this compound

By orthology

Species	Potential target	Known druggable target/s	Ortholog Group
Schistosoma mansoni	neuropeptide receptor	Get druggable targets OG5_127863	All targets in OG5_127863
Echinococcus granulosus	neuropeptide receptor	Get druggable targets OG5_127863	All targets in OG5_127863
Echinococcus multilocularis	G protein coupled receptor 139	Get druggable targets OG5_127863	All targets in OG5_127863
Echinococcus multilocularis	neuropeptide receptor	Get druggable targets OG5_127863	All targets in OG5_127863
Schistosoma japonicum	ko:K04209 neuropeptide Y receptor, invertebrate, putative	Get druggable targets OG5_127863	All targets in OG5_127863

By sequence similarity to non orthologous known druggable targets

Species	Potential target	Known druggable target	Length	Alignment span	Identity
Echinococcus granulosus	sex peptide receptor	hypocretin (orexin) receptor 1	425 aa	350 aa	23.4 %

Ranking Plot

Putative Targets List

Species	Potential target	Raw	Global	Species
Echinococcus granulosus	cathepsin L	0.0016	0.0029	0.0024
Loa Loa (eye worm)	hypothetical protein	0.0127	0.1344	0.1344
Brugia malayi	steroid hormone receptor	0.0278	0.3134	0.3125
Schistosoma mansoni	microtubule-associated protein tau	0.0697	0.8087	0.8085
Trypanosoma cruzi	calpain-like cysteine peptidase, putative	0.0035	0.0253	0.0382
Schistosoma mansoni	SmCL2-like peptidase (C01 family)	0.0016	0.0029	0.002
Echinococcus granulosus	cathepsin L cysteine protease	0.0016	0.0029	0.0024
Leishmania major	hypothetical protein, conserved	0.003	0.0199	0.0902
Echinococcus multilocularis	retinoic acid receptor rxr beta a retinoic acid receptor rxr alpha a retinoic acid receptor rxr alpha	0.0131	0.1394	0.1457
Trypanosoma brucei	centrin, putative	0.003	0.0194	0.0965
Echinococcus granulosus	G protein coupled 5 hydroxytryptamine receptor	0.0127	0.1344	0.1405
Brugia malayi	nuclear hormone receptor	0.0278	0.3134	0.3125
Trichomonas vaginalis	conserved hypothetical protein	0.0035	0.0253	0.0234
Schistosoma mansoni	glutamate receptor NMDA	0.0062	0.0572	0.0563
Brugia malayi	intermediate filament protein	0.0029	0.0184	0.0171
Echinococcus granulosus	nmda type glutamate receptor	0.0026	0.0149	0.015
Leishmania major	hypothetical protein, conserved	0.0073	0.0708	0.3595
Trypanosoma cruzi	cysteine peptidase, Clan CA, family C2, putative	0.0035	0.0253	0.0382
Echinococcus granulosus	fmrfamide receptor	0.0127	0.1344	0.1405
Trypanosoma cruzi	cysteine peptidase, Clan CA, family C2, putative	0.0135	0.1433	0.2312
Plasmodium vivax	cysteine repeat modular protein 1, putative	0.0071	0.0679	0.4672
Loa Loa (eye worm)	calpain 5	0.01	0.102	0.102
Loa Loa (eye worm)	hypothetical protein	0.0015	0.0013	0.0013
Echinococcus granulosus	lamin dm0	0.0029	0.0184	0.0187
Brugia malayi	hypothetical protein	0.0147	0.158	0.1569
Trypanosoma cruzi	cysteine peptidase, Clan CA, family C2, putative	0.0035	0.0253	0.0382
Echinococcus granulosus	EF hand domain containing family member A2	0.003	0.0199	0.0203
Leishmania major	hypothetical protein, conserved	0.0035	0.0253	0.1184
Trypanosoma cruzi	apurinic/apyrimidinic endonuclease	0.0038	0.0286	0.0436
Schistosoma mansoni	rhodopsin-like orphan GPCR	0.0127	0.1344	0.1336
Plasmodium falciparum	dipeptidyl aminopeptidase 2	0.0016	0.0029	0.0156
Onchocerca volvulus		0.0127	0.1344	0.4264
Echinococcus multilocularis	sex peptide receptor	0.0127	0.1344	0.1405
Schistosoma mansoni	family S12 unassigned peptidase (S12 family)	0.0073	0.0708	0.0699
Loa Loa (eye worm)	hypothetical protein	0.0127	0.1344	0.1344
Echinococcus multilocularis	cathepsin b	0.0532	0.6135	0.6437
Echinococcus multilocularis	neuropeptide receptor	0.0127	0.1344	0.1405
Schistosoma mansoni	biogenic amine (5HT) receptor	0.0127	0.1344	0.1336
Loa Loa (eye worm)	hypothetical protein	0.0278	0.3134	0.3134
Onchocerca volvulus		0.0127	0.1344	0.4264
Trypanosoma cruzi	caltractin, putative	0.003	0.0194	0.0287
Brugia malayi	hypothetical protein	0.0127	0.1344	0.1332
Echinococcus granulosus	neuropeptides capa receptor	0.0127	0.1344	0.1405
Trichomonas vaginalis	Clan CA, family C1, cathepsin L-like cysteine peptidase	0.0016	0.0029	0.001
Echinococcus multilocularis	serotonin receptor	0.0372	0.4241	0.4448
Trichomonas vaginalis	Clan CA, family C1, cathepsin L-like cysteine peptidase	0.0016	0.0029	0.001
Trichomonas vaginalis	calcium binding protein, putative	0.003	0.0194	0.0176
Brugia malayi	ORL1-like opioid receptor	0.0127	0.1344	0.1332
Echinococcus multilocularis	tachykinin peptides receptor 99D	0.0127	0.1344	0.1405
Leishmania major	calpain, putative,cysteine peptidase, Clan CA, family C2, putative	0.0135	0.1433	0.7432
Plasmodium falciparum	importin beta, putative	0.003	0.0192	0.2615
Echinococcus multilocularis	g-protein coupled receptor	0.0127	0.1344	0.1405
Trypanosoma cruzi	calpain-like cysteine peptidase, putative	0.0135	0.1433	0.2312
Loa Loa (eye worm)	hypothetical protein	0.0016	0.0029	0.0029
Onchocerca volvulus		0.0015	0.0019	0.0017
Trypanosoma brucei	cysteine peptidase, Clan CA, family C2, putative	0.0035	0.0253	0.1272
Trypanosoma brucei	Present in the outer mitochondrial membrane proteome 33	0.003	0.0194	0.0965
Brugia malayi	NAD-dependent malic enzyme, mitochondrial precursor, putative	0.0025	0.0139	0.0125
Loa Loa (eye worm)	exodeoxyribonuclease III family protein	0.0038	0.0286	0.0286
Giardia lamblia	Dipeptidyl-peptidase I precursor	0.0016	0.0029	0.0054
Trypanosoma cruzi	cysteine peptidase, putative	0.0016	0.0029	0.0017
Loa Loa (eye worm)	PAN domain-containing protein	0.0015	0.0013	0.0013
Loa Loa (eye worm)	hypothetical protein	0.0127	0.1344	0.1344
Schistosoma mansoni	biogenic amine (5HT) receptor	0.0372	0.4241	0.4236
Giardia lamblia	Cathepsin L-like protease	0.0016	0.0029	0.0054
Echinococcus multilocularis	growth hormone secretagogue receptor type 1	0.0127	0.1344	0.1405
Trypanosoma cruzi	cytoskeleton-associated protein CAP5.5, putative	0.0035	0.0253	0.0382
Mycobacterium tuberculosis	Possible DNA-damage-inducible protein P DinP (DNA polymerase V) (pol IV 2) (DNA nucleotidyltransferase (DNA-directed))	0.0021	0.0086	0.0045
Brugia malayi	AKH receptor	0.0127	0.1344	0.1332
Trypanosoma brucei	calpain-like cysteine peptidase, putative	0.0035	0.0253	0.1272
Wolbachia endosymbiont of Brugia malayi	exonuclease III	0.0038	0.0286	0.5
Onchocerca volvulus		0.0047	0.0395	0.1224
Trypanosoma cruzi	kinesin, putative	0.01	0.102	0.1637
Echinococcus multilocularis	allatostatin A receptor	0.0127	0.1344	0.1405
Echinococcus multilocularis	rhodopsin orphan GPCR	0.0127	0.1344	0.1405
Schistosoma mansoni	hypothetical protein	0.0183	0.2002	0.1995
Schistosoma mansoni	retinoid-x-receptor (RXR)	0.0278	0.3134	0.3127
Echinococcus multilocularis	programmed cell death protein 6	0.0016	0.0024	0.0019
Brugia malayi	calpain 7	0.0135	0.1433	0.1421
Echinococcus granulosus	neuropeptide FF receptor 2	0.0127	0.1344	0.1405
Onchocerca volvulus	Malic enzyme homolog	0.0025	0.0139	0.0401
Entamoeba histolytica	papain family cysteine protease domain containing protein	0.0016	0.0029	0.0103
Loa Loa (eye worm)	papain family cysteine protease containing protein	0.0016	0.0029	0.0029
Brugia malayi	hypothetical protein	0.0127	0.1344	0.1332
Echinococcus multilocularis	survival motor neuron protein 1	0.023	0.2562	0.2685
Loa Loa (eye worm)	Papain cysteine protease/cathepsin propeptide inhibitor-containing protein	0.0016	0.0029	0.0029
Plasmodium falciparum	cysteine repeat modular protein 1	0.0071	0.0679	1
Leishmania major	calpain protease-like protein	0.0035	0.0253	0.1184
Echinococcus granulosus	sex peptide receptor	0.0127	0.1344	0.1405
Plasmodium falciparum	dipeptidyl aminopeptidase 1	0.0016	0.0029	0.0156
Trypanosoma cruzi	programmed cell death 6 protein-like, putative	0.003	0.0194	0.0287
Echinococcus multilocularis	family C2 unassigned peptidase (C02 family)	0.04	0.4572	0.4795
Trichomonas vaginalis	Importin beta-1 subunit, putative	0.0024	0.0125	0.0107
Loa Loa (eye worm)	hypothetical protein	0.0016	0.0029	0.0029
Echinococcus multilocularis	thyroid hormone receptor alpha	0.0278	0.3134	0.3285
Trichomonas vaginalis	Clan CA, family C1, cathepsin B-like cysteine peptidase	0.0016	0.0029	0.001
Loa Loa (eye worm)	hypothetical protein	0.0131	0.1394	0.1394
Loa Loa (eye worm)	hypothetical protein	0.0372	0.4241	0.4241
Onchocerca volvulus		0.0235	0.2626	0.8372
Brugia malayi	Dopamine receptor protein 2	0.0127	0.1344	0.1332
Leishmania major	hypothetical protein, conserved	0.003	0.0194	0.0874
Brugia malayi	Papain family cysteine protease containing protein	0.0016	0.0029	0.0016
Brugia malayi	hypothetical protein	0.0127	0.1344	0.1332
Onchocerca volvulus		0.0016	0.0029	0.005
Brugia malayi	cathepsin L precursor	0.0016	0.0029	0.0016
Loa Loa (eye worm)	hypothetical protein	0.0127	0.1344	0.1344
Entamoeba histolytica	Ran family GTPase	0.0022	0.0099	0.0799
Plasmodium falciparum	AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative	0.0038	0.0286	0.404
Echinococcus multilocularis	peptide (allatostatin:somatostatin)	0.0127	0.1344	0.1405
Brugia malayi	fibroinase precursor	0.0016	0.0029	0.0016
Loa Loa (eye worm)	melatonin receptor type 1A	0.0127	0.1344	0.1344
Onchocerca volvulus		0.0057	0.052	0.1625
Schistosoma mansoni	neuropeptide receptor	0.0127	0.1344	0.1336
Trypanosoma cruzi	calmodulin, putative	0.003	0.0194	0.0287
Trypanosoma cruzi	DNA polymerase kappa, putative	0.0021	0.0086	0.0111
Plasmodium vivax	vivapain-1	0.0016	0.0029	0.0073
Echinococcus granulosus	Nuclear hormone receptor HR96	0.0131	0.1394	0.1457
Entamoeba histolytica	cysteine proteinase, putative	0.0016	0.0029	0.0103
Loa Loa (eye worm)	hypothetical protein	0.0127	0.1344	0.1344
Trypanosoma brucei	centrin, putative	0.003	0.0194	0.0965
Loa Loa (eye worm)	hypothetical protein	0.0131	0.1394	0.1394
Onchocerca volvulus	Malic enzyme homolog	0.0025	0.0139	0.0401
Giardia lamblia	Dipeptidyl-peptidase I precursor	0.0016	0.0029	0.0054
Loa Loa (eye worm)	hypothetical protein	0.0127	0.1344	0.1344
Toxoplasma gondii	EF hand domain-containing protein	0.003	0.0194	0.0949
Brugia malayi	Iron-sulfur cluster assembly accessory protein	0.0047	0.0395	0.0383
Trypanosoma brucei	calpain-like protein, putative	0.0135	0.1433	0.7458
Schistosoma mansoni	calmodulin	0.003	0.0194	0.0185
Plasmodium vivax	vivapain-2	0.0016	0.0029	0.0073
Echinococcus granulosus	cathepsin b	0.0532	0.6135	0.6437
Echinococcus multilocularis	neuropeptides capa receptor	0.0127	0.1344	0.1405
Onchocerca volvulus		0.0127	0.1344	0.4264
Loa Loa (eye worm)	hypothetical protein	0.003	0.0192	0.0192
Toxoplasma gondii	calcium binding protein precursor, putative	0.0015	0.0019	0.0028
Brugia malayi	hypothetical protein	0.0127	0.1344	0.1332
Schistosoma mansoni	hypothetical protein	0.003	0.0194	0.0185
Schistosoma mansoni	hypothetical protein	0.0183	0.2002	0.1995
Mycobacterium tuberculosis	Probable hydrolase	0.0073	0.0708	0.1213
Schistosoma mansoni	cathepsin B-like peptidase (C01 family)	0.0016	0.0029	0.002
Leishmania major	phospholipase c-like protein	0.003	0.0194	0.0874
Trichomonas vaginalis	hypothetical protein	0.0035	0.0253	0.0234
Leishmania major	calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative	0.0035	0.0253	0.1184
Treponema pallidum	exodeoxyribonuclease (exoA)	0.0038	0.0286	1
Loa Loa (eye worm)	ImpB/MucB/SamB family protein	0.0021	0.0086	0.0086
Loa Loa (eye worm)	hypothetical protein	0.0532	0.6135	0.6135
Loa Loa (eye worm)	hypothetical protein	0.0127	0.1344	0.1344
Echinococcus multilocularis	calmodulin	0.003	0.0194	0.0197
Toxoplasma gondii	hypothetical protein	0.0035	0.0253	0.1257
Brugia malayi	Nuclear hormone receptor family member nhr-49	0.0278	0.3134	0.3125
Trichomonas vaginalis	centrin, putative	0.003	0.0194	0.0176
Echinococcus multilocularis	g protein linked acetylcholine receptor gar 2a	0.0127	0.1344	0.1405
Leishmania major	calmodulin, putative	0.003	0.0194	0.0874
Mycobacterium tuberculosis	Probable esterase/lipase LipP	0.0073	0.0708	0.1213
Schistosoma mansoni	amine GPCR	0.0127	0.1344	0.1336
Entamoeba histolytica	cysteine proteinase, putative	0.0016	0.0029	0.0103
Brugia malayi	MH2 domain containing protein	0.0121	0.1267	0.1255
Schistosoma mansoni	neuropeptide F-like receptor	0.0127	0.1344	0.1336
Trypanosoma brucei	DNA polymerase kappa, putative	0.0021	0.0086	0.0401
Echinococcus multilocularis	biogenic amine (5HT) receptor	0.0127	0.1344	0.1405
Leishmania major	calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative	0.0035	0.0253	0.1184
Schistosoma mansoni	hypothetical protein	0.0127	0.1344	0.1336
Schistosoma mansoni	family C2 unassigned peptidase (C02 family)	0.037	0.4218	0.4213
Echinococcus granulosus	programmed cell death protein 6	0.0016	0.0024	0.0019
Loa Loa (eye worm)	PAN domain-containing protein	0.0015	0.0013	0.0013
Onchocerca volvulus		0.003	0.0194	0.0579
Echinococcus multilocularis	neuropeptide Y receptor	0.0127	0.1344	0.1405
Schistosoma mansoni	rhodopsin-like orphan GPCR	0.0127	0.1344	0.1336
Leishmania major	calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative	0.0035	0.0253	0.1184
Schistosoma mansoni	subfamily C1A unassigned peptidase (C01 family)	0.0016	0.0029	0.002
Brugia malayi	cathepsin B-like cysteine proteinase	0.0532	0.6135	0.613
Trichomonas vaginalis	Clan CA, family C1, cathepsin L-like cysteine peptidase	0.0016	0.0029	0.001
Brugia malayi	G-protein coupled receptor	0.0127	0.1344	0.1332
Loa Loa (eye worm)	nuclear hormone receptor-like 1	0.0147	0.158	0.158
Brugia malayi	hypothetical protein	0.0127	0.1344	0.1332
Schistosoma mansoni	nuclear receptor nhr-48	0.0131	0.1394	0.1386
Echinococcus granulosus	G protein coupled receptor 139	0.0127	0.1344	0.1405
Schistosoma mansoni	family C2 unassigned peptidase (C02 family)	0.04	0.4572	0.4567
Onchocerca volvulus		0.0127	0.1344	0.4264
Trypanosoma cruzi	cysteine protease, putative	0.0016	0.0029	0.0017
Trypanosoma cruzi	calmodulin, putative	0.003	0.0194	0.0287
Entamoeba histolytica	cysteine protease, putative	0.0016	0.0029	0.0103
Loa Loa (eye worm)	hypothetical protein	0.0016	0.0029	0.0029
Trypanosoma cruzi	cysteine peptidase, Clan CA, family C2, putative	0.0035	0.0253	0.0382
Trichomonas vaginalis	Clan CA, family C1, papain-like cysteine peptidase	0.0016	0.0029	0.001
Mycobacterium ulcerans	fusion of enoyl-CoA hydratase, EchA21 and lipase, LipE	0.0073	0.0708	0.0649
Trichomonas vaginalis	Clan CA, family C1, cathepsin B-like cysteine peptidase	0.0176	0.1918	0.1902
Loa Loa (eye worm)	cysteine protease	0.0016	0.0029	0.0029
Echinococcus multilocularis	calcium uptake protein 1	0.003	0.0199	0.0203
Trichomonas vaginalis	Clan CA, family C1, cathepsin L-like cysteine peptidase	0.0016	0.0029	0.001
Plasmodium falciparum	cysteine proteinase falcipain 2a	0.0016	0.0029	0.0156
Trichomonas vaginalis	Clan CA, family C1, cathepsin L-like cysteine peptidase	0.0016	0.0029	0.001
Brugia malayi	cytoplasmic intermediate filament protein	0.0016	0.0025	0.0011
Entamoeba histolytica	cysteine protease, putative	0.0016	0.0029	0.0103
Schistosoma mansoni	myosin light chain	0.0015	0.0019	0.001
Entamoeba histolytica	EF-hand calcium-binding domain containing protein	0.003	0.0194	0.175
Echinococcus multilocularis	orexin receptor type 2	0.0127	0.1344	0.1405
Plasmodium vivax	hypothetical protein, conserved	0.0073	0.0708	0.4874
Brugia malayi	Nuclear hormone receptor family member nhr-14	0.0278	0.3134	0.3125
Loa Loa (eye worm)	hypothetical protein	0.0127	0.1344	0.1344
Echinococcus granulosus	dna polymerase eta	0.0021	0.0086	0.0084
Loa Loa (eye worm)	hypothetical protein	0.0015	0.0013	0.0013
Loa Loa (eye worm)	hypothetical protein	0.0015	0.0019	0.0019
Loa Loa (eye worm)	hypothetical protein	0.0127	0.1344	0.1344
Loa Loa (eye worm)	hypothetical protein	0.0029	0.0178	0.0178
Trypanosoma cruzi	cytoskeleton-associated protein CAP5.5, putative	0.0035	0.0253	0.0382
Echinococcus multilocularis	NADP dependent malic enzyme	0.0025	0.0139	0.0139
Onchocerca volvulus		0.0131	0.1394	0.4424
Echinococcus granulosus	peptide allatostatin:somatostatin	0.0127	0.1344	0.1405
Trypanosoma brucei	centrin-3	0.0045	0.0373	0.1901
Leishmania major	hypothetical protein, conserved	0.0071	0.0679	0.3444
Schistosoma mansoni	calmodulin	0.003	0.0194	0.0185
Echinococcus granulosus	neuropeptide Y receptor	0.0127	0.1344	0.1405
Schistosoma mansoni	rhodopsin-like orphan GPCR	0.0127	0.1344	0.1336
Echinococcus multilocularis	cathepsin L cysteine protease	0.0016	0.0029	0.0024
Echinococcus granulosus	Basic leucine zipper bZIP transcription	0.0036	0.027	0.0277
Echinococcus granulosus	calcium uptake protein 1	0.003	0.0199	0.0203
Brugia malayi	Importin beta-1 subunit	0.003	0.0192	0.0178
Loa Loa (eye worm)	cathepsin B	0.0176	0.1918	0.1918
Schistosoma mansoni	calcium binding atopy-related autoantigen	0.003	0.0199	0.019
Loa Loa (eye worm)	hypothetical protein	0.0147	0.158	0.158
Schistosoma mansoni	biogenic amine (dopamine) receptor	0.0127	0.1344	0.1336
Loa Loa (eye worm)	hypothetical protein	0.0278	0.3134	0.3134
Echinococcus granulosus	g protein coupled receptor	0.0127	0.1344	0.1405
Schistosoma mansoni	centrin	0.003	0.0194	0.0185
Entamoeba histolytica	protein kinase, putative	0.01	0.102	1
Plasmodium vivax	serine-repeat antigen (SERA)	0.0016	0.0029	0.0073
Brugia malayi	G protein-coupled receptor F59B2.13	0.0127	0.1344	0.1332
Leishmania major	calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative	0.0035	0.0253	0.1184
Trypanosoma brucei	DNA polymerase kappa, putative	0.0021	0.0086	0.0401
Echinococcus granulosus	biogenic amine 5HT receptor	0.0127	0.1344	0.1405
Loa Loa (eye worm)	nuclear hormone receptor family member nhr-1	0.0278	0.3134	0.3134
Plasmodium falciparum	serine repeat antigen 6	0.0016	0.0029	0.0156
Plasmodium falciparum	serine repeat antigen 4	0.0016	0.0029	0.0156
Loa Loa (eye worm)	hypothetical protein	0.0131	0.1394	0.1394
Plasmodium vivax	serine-repeat antigen 5 (SERA)	0.0016	0.0029	0.0073
Giardia lamblia	Hypothetical protein	0.0016	0.0029	0.0054
Echinococcus multilocularis	Nuclear hormone receptor HR96	0.0131	0.1394	0.1457
Toxoplasma gondii	calpain family cysteine protease domain-containing protein	0.0035	0.0253	0.1257
Trypanosoma brucei	calpain, putative	0.0035	0.0253	0.1272
Trichomonas vaginalis	Clan CA, family C1, papain-like cysteine peptidase	0.0016	0.0029	0.001
Toxoplasma gondii	calmodulin CAM2	0.0015	0.0019	0.0028
Leishmania major	centrin, putative	0.003	0.0194	0.0874
Schistosoma mansoni	biogenic amine (dopamine) receptor	0.0127	0.1344	0.1336
Mycobacterium ulcerans	esterase/lipase LipP	0.0073	0.0708	0.0649
Trichomonas vaginalis	Clan CA, family C1, papain-like cysteine peptidase	0.0016	0.0029	0.001
Onchocerca volvulus		0.0071	0.0679	0.2134
Brugia malayi	GnHR receptor homolog	0.0127	0.1344	0.1332
Onchocerca volvulus		0.0029	0.0184	0.0548
Giardia lamblia	Cathepsin B precursor	0.0016	0.0029	0.0054
Giardia lamblia	DINP protein human, muc B family	0.0021	0.0086	0.0356
Brugia malayi	Nuclear hormone receptor family member nhr-1	0.0278	0.3134	0.3125
Echinococcus multilocularis	nmda type glutamate receptor	0.0026	0.0149	0.015
Trichomonas vaginalis	Clan CA, family C1, cathepsin B-like cysteine peptidase	0.0016	0.0029	0.001
Loa Loa (eye worm)	hypothetical protein	0.023	0.2562	0.2562
Schistosoma mansoni	cathepsin F (C01 family)	0.0016	0.0029	0.002
Entamoeba histolytica	cysteine protease, putative	0.0016	0.0029	0.0103
Loa Loa (eye worm)	PAN domain-containing protein	0.0015	0.0013	0.0013
Leishmania major	kinesin, putative	0.01	0.102	0.5248
Trypanosoma brucei	calpain-like protein, putative	0.0135	0.1433	0.7458
Brugia malayi	nuclear receptor NHR-88	0.0131	0.1394	0.1382
Loa Loa (eye worm)	hypothetical protein	0.0016	0.0029	0.0029
Echinococcus multilocularis	calpain 5	0.0135	0.1433	0.1498
Trypanosoma cruzi	GTP-binding nuclear protein rtb2, putative	0.0022	0.0099	0.0131
Echinococcus multilocularis	hypothetical protein	0.0135	0.1433	0.1498
Brugia malayi	hypothetical protein	0.0036	0.027	0.0257
Echinococcus granulosus	cathepsin L	0.0016	0.0029	0.0024
Loa Loa (eye worm)	hypothetical protein	0.0372	0.4241	0.4241
Entamoeba histolytica	grainin 2	0.0045	0.0373	0.3534
Trichomonas vaginalis	conserved hypothetical protein	0.003	0.0194	0.0176
Brugia malayi	follicle stimulating hormone receptor	0.0127	0.1344	0.1332
Echinococcus multilocularis	pyroglutamylated rfamide peptide receptor	0.0127	0.1344	0.1405
Trypanosoma cruzi	calpain-like cysteine peptidase, putative	0.0135	0.1433	0.2312
Toxoplasma gondii	preprocathepsin c precursor, putative	0.0016	0.0029	0.0082
Echinococcus multilocularis	beta LACTamase domain containing family member	0.0073	0.0708	0.0737
Brugia malayi	Nuclear hormone receptor family member nhr-31	0.0278	0.3134	0.3125
Echinococcus granulosus	tm gpcr rhodopsin	0.0127	0.1344	0.1405
Plasmodium vivax	vivapain-3	0.0016	0.0029	0.0073
Trypanosoma brucei	cysteine peptidase, Clan CA, family C1, Cathepsin L-like	0.0016	0.0029	0.01
Echinococcus multilocularis	ecdysone induced protein 78C	0.0278	0.3134	0.3285
Echinococcus multilocularis	G protein coupled receptor 139	0.0251	0.2804	0.2939
Entamoeba histolytica	calmodulin, putative	0.003	0.0194	0.175
Echinococcus granulosus	cathepsin l1	0.0016	0.0029	0.0024
Trichomonas vaginalis	calmodulin, putative	0.003	0.0194	0.0176
Brugia malayi	Nuclear hormone receptor family member nhr-25	0.0278	0.3134	0.3125
Onchocerca volvulus	Cathepsin L homolog	0.0016	0.0029	0.005
Echinococcus multilocularis	Nuclear hormone receptor family member nhr 41	0.0278	0.3134	0.3285
Echinococcus multilocularis	NADP dependent malic enzyme	0.0025	0.0139	0.0139
Trichomonas vaginalis	D-aminoacylase, putative	0.0073	0.0708	0.069
Trichomonas vaginalis	calcineurin B subunit, putative	0.003	0.0199	0.0181
Loa Loa (eye worm)	hypothetical protein	0.0147	0.158	0.158
Echinococcus granulosus	programmed cell death protein	0.0045	0.0373	0.0385
Trypanosoma cruzi	cysteine peptidase, putative	0.0016	0.0029	0.0017
Trichomonas vaginalis	Clan CA, family C2, calpain-like cysteine peptidase	0.0035	0.0253	0.0234
Trichomonas vaginalis	calpain, putative	0.0035	0.0253	0.0234
Schistosoma mansoni	peptide (allatostatin)-like receptor	0.0127	0.1344	0.1336
Schistosoma mansoni	cpg binding protein	0.0061	0.0559	0.0551
Schistosoma mansoni	cpg binding protein	0.0061	0.0559	0.0551
Trypanosoma cruzi	apurinic/apyrimidinic endonuclease, putative	0.0038	0.0286	0.0436
Trypanosoma cruzi	cysteine peptidase C (CPC), putative	0.0176	0.1918	0.3104
Trichomonas vaginalis	Clan CA, family C1, papain-like cysteine peptidase	0.0016	0.0029	0.001
Echinococcus granulosus	rhodopsin orphan GPCR	0.0127	0.1344	0.1405
Loa Loa (eye worm)	hypothetical protein	0.0131	0.1394	0.1394
Echinococcus granulosus	rhodopsin orphan GPCR	0.0127	0.1344	0.1405
Schistosoma mansoni	biogenic amine receptor	0.0127	0.1344	0.1336
Leishmania major	calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative	0.0035	0.0253	0.1184
Echinococcus granulosus	intermediate filament protein	0.0029	0.0184	0.0187
Schistosoma mansoni	histamine h1 receptor	0.0127	0.1344	0.1336
Echinococcus multilocularis	dna polymerase eta	0.0021	0.0086	0.0084
Echinococcus multilocularis	calmodulin	0.003	0.0194	0.0197
Schistosoma mansoni	biogenic amine receptor	0.0127	0.1344	0.1336
Trichomonas vaginalis	calpain, putative	0.0035	0.0253	0.0234
Brugia malayi	Probable myosin regulatory light chain	0.0016	0.0024	0.0011
Loa Loa (eye worm)	hypothetical protein	0.0278	0.3134	0.3134
Loa Loa (eye worm)	ctsf protein	0.0016	0.0029	0.0029
Schistosoma mansoni	nuclear hormone receptor	0.0131	0.1394	0.1386
Schistosoma mansoni	survival motor neuron protein	0.0047	0.0395	0.0387
Echinococcus granulosus	sarcoplasmic calcium binding protein	0.003	0.0194	0.0197
Loa Loa (eye worm)	gonadotropin-releasing hormone receptor 2	0.0127	0.1344	0.1344
Brugia malayi	beta-lactamase family protein	0.0073	0.0708	0.0695
Loa Loa (eye worm)	hypothetical protein	0.0073	0.0708	0.0708
Echinococcus granulosus	calpain A	0.0135	0.1433	0.1498
Echinococcus multilocularis	calumenin	0.003	0.0199	0.0203
Mycobacterium ulcerans	exodeoxyribonuclease III protein XthA	0.0038	0.0286	0.0225
Mycobacterium tuberculosis	Probable esterase LipL	0.0073	0.0708	0.1213
Echinococcus multilocularis	lamin dm0	0.0029	0.0184	0.0187
Entamoeba histolytica	cysteine protease, putative	0.0016	0.0029	0.0103
Entamoeba histolytica	deoxycytidyl transferase, putative	0.0021	0.0086	0.0676
Echinococcus multilocularis	G-protein coupled receptor, putative	0.0127	0.1344	0.1405
Trypanosoma brucei	DNA polymerase kappa, putative	0.0021	0.0086	0.0401
Brugia malayi	Cathepsin L-like precursor	0.0016	0.0029	0.0016
Entamoeba histolytica	cysteine protease, putative	0.0016	0.0029	0.0103
Trichomonas vaginalis	Clan CA, family C1, cathepsin L-like cysteine peptidase	0.0016	0.0029	0.001
Loa Loa (eye worm)	calpain family protein 1	0.027	0.3038	0.3038
Trypanosoma cruzi	calpain-like cysteine peptidase, putative	0.0035	0.0253	0.0382
Echinococcus granulosus	g-protein coupled receptor	0.0127	0.1344	0.1405
Trypanosoma cruzi	calpain-like cysteine peptidase, putative	0.0035	0.0253	0.0382
Giardia lamblia	Cathepsin L precursor	0.0016	0.0029	0.0054
Mycobacterium ulcerans	DNA polymerase IV	0.0021	0.0086	0.0024
Brugia malayi	neuropeptide F receptor	0.0127	0.1344	0.1332
Echinococcus granulosus	growth hormone secretagogue receptor type 1	0.0127	0.1344	0.1405
Entamoeba histolytica	hypothetical protein	0.0036	0.027	0.251
Trichomonas vaginalis	ap endonuclease, putative	0.0038	0.0286	0.0267
Toxoplasma gondii	cathepsin B	0.0176	0.1918	1
Toxoplasma gondii	cathepsin CPC1	0.0016	0.0029	0.0082
Echinococcus multilocularis	neuropeptide s receptor	0.0127	0.1344	0.1405
Schistosoma mansoni	cathepsin B-like peptidase (C01 family)	0.0532	0.6135	0.6132
Brugia malayi	orphan nuclear receptor NR2E1	0.0131	0.1394	0.1382
Brugia malayi	hypothetical protein	0.0127	0.1344	0.1332
Brugia malayi	Ligand-binding domain of nuclear hormone receptor family protein	0.0278	0.3134	0.3125
Trichomonas vaginalis	Clan CA, family C1, cathepsin L-like cysteine peptidase	0.0016	0.0029	0.001
Giardia lamblia	Endonuclease/Exonuclease/phosphatase	0.0038	0.0286	0.1405
Echinococcus multilocularis	cathepsin L cysteine protease	0.0016	0.0029	0.0024
Brugia malayi	Cathepsin L-like precursor	0.0016	0.0029	0.0016
Trichomonas vaginalis	ap endonuclease, putative	0.0038	0.0286	0.0267
Brugia malayi	sulfakinin receptor protein	0.0127	0.1344	0.1332
Trichomonas vaginalis	conserved hypothetical protein	0.0016	0.0029	0.001
Echinococcus granulosus	nuclear receptor subfamily 1 group D	0.0147	0.158	0.1653
Trichomonas vaginalis	Clan CA, family C1, cathepsin L-like cysteine peptidase	0.0016	0.0029	0.001
Echinococcus multilocularis	lamin	0.0029	0.0184	0.0187
Schistosoma mansoni	ap endonuclease	0.0038	0.0286	0.0277
Entamoeba histolytica	cysteine protease, putative	0.0016	0.0029	0.0103
Trypanosoma brucei	DNA polymerase IV, putative	0.0021	0.0086	0.0401
Brugia malayi	Dopamine receptor protein 1	0.0127	0.1344	0.1332
Schistosoma mansoni	mixed-lineage leukemia protein mll	0.0122	0.1283	0.1275
Schistosoma mansoni	rhodopsin-like orphan GPCR	0.0127	0.1344	0.1336
Trichomonas vaginalis	Clan CA, family C1, papain-like cysteine peptidase	0.0016	0.0029	0.001
Toxoplasma gondii	cathepsin CPL	0.0016	0.0029	0.0082
Schistosoma mansoni	photoreceptor-specific nuclear receptor related	0.0278	0.3134	0.3127
Trichomonas vaginalis	Clan CA, family C1, cathepsin L-like cysteine peptidase	0.0016	0.0029	0.001
Echinococcus granulosus	alpha 1A adrenergic receptor	0.0127	0.1344	0.1405
Leishmania major	calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative	0.0035	0.0253	0.1184
Brugia malayi	hypothetical protein	0.0127	0.1344	0.1332
Echinococcus multilocularis	glutamate (NMDA) receptor subunit	0.0062	0.0572	0.0594
Mycobacterium tuberculosis	Probable lipase LipE	0.0073	0.0708	0.1213
Schistosoma mansoni	ap endonuclease	0.0038	0.0286	0.0277
Schistosoma mansoni	opsin-like receptor	0.0127	0.1344	0.1336
Brugia malayi	cahepsin L-like non-peptiedase homolog	0.0016	0.0029	0.0016
Echinococcus granulosus	dro:myosuppressin receptor	0.0127	0.1344	0.1405
Chlamydia trachomatis	glutamine binding protein	0.0019	0.0063	0.5
Schistosoma mansoni	rhodopsin-like orphan GPCR	0.0127	0.1344	0.1336
Entamoeba histolytica	cysteine proteinase, putative	0.0016	0.0029	0.0103
Entamoeba histolytica	hypothetical protein	0.0016	0.0029	0.0103
Loa Loa (eye worm)	hypothetical protein	0.0127	0.1344	0.1344
Toxoplasma gondii	exonuclease III APE	0.0038	0.0286	0.143
Loa Loa (eye worm)	hypothetical protein	0.0131	0.1394	0.1394
Schistosoma mansoni	peptide (FMRFamide/somatostatin)-like receptor	0.0127	0.1344	0.1336
Loa Loa (eye worm)	hypothetical protein	0.0278	0.3134	0.3134
Schistosoma mansoni	nuclear hormone receptor superfamily protein-related	0.0131	0.1394	0.1386
Plasmodium vivax	centrin-1, putative	0.003	0.0194	0.124
Entamoeba histolytica	cysteine protease, putative	0.0016	0.0029	0.0103
Onchocerca volvulus	Malic enzyme homolog	0.0025	0.0139	0.0401
Brugia malayi	Dopamine receptor protein 1, putative (partial)	0.0127	0.1344	0.1332
Loa Loa (eye worm)	programmed cell death protein 6	0.003	0.0199	0.0199
Trypanosoma cruzi	Present in the outer mitochondrial membrane proteome 33	0.003	0.0199	0.0295
Echinococcus granulosus	ecdysone induced protein 78C	0.0278	0.3134	0.3285
Echinococcus granulosus	snurportin 1	0.0317	0.3591	0.3765
Echinococcus granulosus	EF HAND 1 calcium binding site	0.003	0.0194	0.0197
Brugia malayi	Steroid receptor seven-up type 2	0.0278	0.3134	0.3125
Brugia malayi	putative neuropeptide receptor	0.0127	0.1344	0.1332
Onchocerca volvulus	Dopamine\/Ecdysteroid receptor homolog	0.0127	0.1344	0.4264
Trypanosoma cruzi	calpain-like cysteine peptidase, putative	0.0135	0.1433	0.2312
Onchocerca volvulus		0.0127	0.1344	0.4264
Loa Loa (eye worm)	papain family cysteine protease containing protein	0.0016	0.0029	0.0029
Trypanosoma cruzi	cysteine peptidase, Clan CA, family C2, putative	0.0135	0.1433	0.2312
Trypanosoma brucei	DNA polymerase kappa, putative	0.0021	0.0086	0.0401
Plasmodium falciparum	dipeptidyl aminopeptidase 3	0.0016	0.0029	0.0156
Onchocerca volvulus	Cathepsin L homolog	0.0016	0.0029	0.005
Brugia malayi	Papain family cysteine protease containing protein	0.0016	0.0029	0.0016
Brugia malayi	Serotonin receptor	0.0127	0.1344	0.1332
Schistosoma mansoni	Mername-AA248 (C02 family)	0.0135	0.1433	0.1425
Brugia malayi	Nuclear hormone receptor family member nhr-19	0.0278	0.3134	0.3125
Echinococcus granulosus	survival motor neuron protein 1	0.023	0.2562	0.2685
Brugia malayi	calpain 5	0.0035	0.0253	0.024
Echinococcus multilocularis	centrin 2	0.003	0.0194	0.0197
Echinococcus granulosus	nuclear receptor nhr 48	0.0131	0.1394	0.1457
Loa Loa (eye worm)	hypothetical protein	0.0127	0.1344	0.1344
Trypanosoma brucei	caltractin, putative	0.0045	0.0373	0.1901
Trypanosoma brucei	calpain-like protein, putative	0.0135	0.1433	0.7458
Trichomonas vaginalis	Importin beta-1 subunit, putative	0.0024	0.0125	0.0107
Loa Loa (eye worm)	nuclear hormone receptor family member nhr-31	0.0278	0.3134	0.3134
Loa Loa (eye worm)	hypothetical protein	0.0127	0.1344	0.1344
Trypanosoma brucei	antigen, putative	0.0135	0.1433	0.7458
Trypanosoma brucei	protein I/6	0.003	0.0194	0.0965
Schistosoma mansoni	cathepsin B-like peptidase (C01 family)	0.0532	0.6135	0.6132
Brugia malayi	photoreceptor-specific nuclear receptor	0.0278	0.3134	0.3125
Schistosoma mansoni	hypothetical protein	0.0819	0.9528	0.9528
Schistosoma mansoni	rab	0.003	0.0194	0.0185
Schistosoma mansoni	Tr4/Tr2 (homologue)	0.0278	0.3134	0.3127
Echinococcus granulosus	Myosin regulatory light chain	0.0015	0.0019	0.0013
Echinococcus multilocularis	calpain	0.0135	0.1433	0.1498
Entamoeba histolytica	cysteine proteinase, putative	0.0016	0.0029	0.0103
Echinococcus multilocularis	neuropeptide receptor A26	0.0127	0.1344	0.1405
Echinococcus multilocularis	nuclear receptor subfamily 1 group D	0.0147	0.158	0.1653
Trichomonas vaginalis	calmodulin, putative	0.003	0.0194	0.0176
Trypanosoma cruzi	GTP-binding nuclear protein rtb2, putative	0.0022	0.0099	0.0131
Echinococcus multilocularis	microtubule associated protein 2	0.0697	0.8087	0.8487
Echinococcus granulosus	importin subunit beta 1	0.003	0.0192	0.0195
Echinococcus multilocularis	somatostatin receptor	0.0127	0.1344	0.1405
Trypanosoma brucei	Component of motile flagella 41	0.003	0.0194	0.0965
Trypanosoma brucei	calpain-like cysteine peptidase, putative	0.0135	0.1433	0.7458
Schistosoma mansoni	nuclear receptor 2DBD-gamma	0.0278	0.3134	0.3127
Loa Loa (eye worm)	hypothetical protein	0.0127	0.1344	0.1344
Loa Loa (eye worm)	DR-78	0.0131	0.1394	0.1394
Loa Loa (eye worm)	beta-LACTamase domain containing family member	0.0073	0.0708	0.0708
Brugia malayi	nuclear receptor RXR	0.0131	0.1394	0.1382
Brugia malayi	glutaminase DH11.1	0.0859	1	1
Schistosoma mansoni	peptide (allatostatin/somatostatin)-like receptor	0.0127	0.1344	0.1336
Trypanosoma cruzi	DNA polymerase kappa, putative	0.0021	0.0086	0.0111
Echinococcus multilocularis	nuclear receptor 2DBD gamma	0.0131	0.1394	0.1457
Trypanosoma cruzi	major cysteine proteinase, putative	0.0016	0.0029	0.0017
Trypanosoma brucei	CAMK/CAMKL family protein kinase, putative	0.003	0.0194	0.0965
Echinococcus multilocularis	tissue type plasminogen activator	0.0071	0.0679	0.0707
Loa Loa (eye worm)	calpain D	0.0035	0.0253	0.0253
Schistosoma mansoni	hypothetical protein	0.0127	0.1344	0.1336
Schistosoma mansoni	opsin-like receptor	0.0127	0.1344	0.1336
Trypanosoma brucei	calpain, putative	0.0035	0.0253	0.1272
Giardia lamblia	Cathepsin B precursor	0.0176	0.1918	1
Leishmania major	DNA polymerase kappa, putative,DNA polymerase IV, putative	0.0021	0.0086	0.0304
Onchocerca volvulus		0.0029	0.0184	0.0548
Echinococcus granulosus	neuropeptides capa receptor	0.0127	0.1344	0.1405
Trichomonas vaginalis	calmodulin, putative	0.003	0.0194	0.0176
Echinococcus multilocularis	calpain family protein 1, d	0.027	0.3038	0.3184
Echinococcus multilocularis	DNA (apurinic or apyrimidinic site) lyase	0.0038	0.0286	0.0293
Echinococcus multilocularis	nuclear receptor 2DBD gamma	0.0278	0.3134	0.3285
Entamoeba histolytica	hypothetical protein	0.0036	0.027	0.251
Loa Loa (eye worm)	hypothetical protein	0.0016	0.0029	0.0029
Schistosoma mansoni	growth hormone secretagogue receptor	0.0127	0.1344	0.1336
Leishmania major	calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative	0.0035	0.0253	0.1184
Trypanosoma brucei	cysteine peptidase C (CPC)	0.0176	0.1918	1
Echinococcus multilocularis	cathepsin L	0.0016	0.0029	0.0024
Loa Loa (eye worm)	hypothetical protein	0.0127	0.1344	0.1344
Schistosoma mansoni	thyroid hormone receptor	0.0278	0.3134	0.3127
Chlamydia trachomatis	arginine ABC transporter substrate-binding protein ArtJ	0.0019	0.0063	0.5
Plasmodium falciparum	serine repeat antigen 2	0.0016	0.0029	0.0156
Echinococcus multilocularis	thyrotropin releasing hormone receptor	0.0127	0.1344	0.1405
Loa Loa (eye worm)	beta-lactamase	0.0073	0.0708	0.0708
Leishmania major	calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative	0.0035	0.0253	0.1184
Echinococcus multilocularis	serotonin receptor	0.0372	0.4241	0.4448
Echinococcus multilocularis	neuropeptides capa receptor	0.0127	0.1344	0.1405
Schistosoma mansoni	subfamily C1A non-peptidase homologue (C01 family)	0.0016	0.0029	0.002
Trypanosoma cruzi	cysteine peptidase, putative	0.0016	0.0029	0.0017
Giardia lamblia	Cathepsin B precursor	0.0016	0.0029	0.0054
Echinococcus multilocularis	neuropeptide Y receptor	0.0127	0.1344	0.1405
Onchocerca volvulus		0.0127	0.1344	0.4264
Echinococcus granulosus	family C2 unassigned peptidase C02 family	0.04	0.4572	0.4795
Schistosoma mansoni	calpain-7 (C02 family)	0.0135	0.1433	0.1425
Schistosoma mansoni	RAR-like nuclear receptor	0.0278	0.3134	0.3127
Trichomonas vaginalis	DNA polymerase eta, putative	0.0021	0.0086	0.0068
Schistosoma mansoni	calmodulin-related	0.0015	0.0019	0.001
Loa Loa (eye worm)	hypothetical protein	0.0127	0.1344	0.1344
Schistosoma mansoni	rhodopsin-like orphan GPCR	0.0127	0.1344	0.1336
Trypanosoma cruzi	hypothetical protein, conserved	0.0073	0.0708	0.1127
Loa Loa (eye worm)	hypothetical protein	0.0021	0.0086	0.0086
Trypanosoma cruzi	calpain cysteine peptidase, putative	0.0035	0.0253	0.0382
Schistosoma mansoni	neuropeptide receptor	0.0251	0.2804	0.2798
Trichomonas vaginalis	Clan CA, family C1, cathepsin L-like cysteine peptidase	0.0016	0.0029	0.001
Brugia malayi	ecdysone receptor	0.0131	0.1394	0.1382
Echinococcus granulosus	centrin 2	0.003	0.0194	0.0197
Onchocerca volvulus	Mitochondrial Rho GTPase homolog	0.0015	0.0019	0.0017
Loa Loa (eye worm)	hypothetical protein	0.0127	0.1344	0.1344
Echinococcus granulosus	cysteine protease	0.0016	0.0029	0.0024
Loa Loa (eye worm)	hypothetical protein	0.0131	0.1394	0.1394
Schistosoma mansoni	myosin xvIII	0.0127	0.1344	0.1336
Loa Loa (eye worm)	hypothetical protein	0.0073	0.0708	0.0708
Trypanosoma cruzi	mitochondrial calcium uptake 1, putative	0.003	0.0194	0.0287
Plasmodium falciparum	cysteine proteinase falcipain 2b	0.0016	0.0029	0.0156
Mycobacterium tuberculosis	Probable conserved lipoprotein	0.0073	0.0708	0.1213
Echinococcus granulosus	g protein coupled receptor	0.0127	0.1344	0.1405
Trypanosoma brucei	calmodulin, putative	0.003	0.0194	0.0965
Echinococcus granulosus	rhodopsin orphan GPCR	0.0127	0.1344	0.1405
Trypanosoma brucei	DNA polymerase IV, putative	0.0021	0.0086	0.0401
Loa Loa (eye worm)	hypothetical protein	0.0015	0.0013	0.0013
Echinococcus granulosus	COUP TF:Svp nuclear hormone receptor	0.0278	0.3134	0.3285
Schistosoma mansoni	cathepsin C	0.0016	0.0029	0.002
Trichomonas vaginalis	DNA-dependent protein kinase catalytic subunit-interacting protein, putative	0.003	0.0194	0.0176
Echinococcus granulosus	tissue type plasminogen activator	0.0071	0.0679	0.0707
Trichomonas vaginalis	Clan CA, family C1, papain-like cysteine peptidase	0.0016	0.0029	0.001
Schistosoma mansoni	glutaminase	0.0859	1	1
Trypanosoma cruzi	centrin, putative	0.0045	0.0373	0.0579
Giardia lamblia	Cysteine protease	0.0016	0.0029	0.0054
Brugia malayi	beta-lactamase	0.0073	0.0708	0.0695
Loa Loa (eye worm)	TYRA-2 protein	0.0127	0.1344	0.1344
Plasmodium falciparum	centrin-1	0.003	0.0194	0.2653
Loa Loa (eye worm)	hypothetical protein	0.0015	0.0013	0.0013
Onchocerca volvulus	Myosin regulatory light chain 2 homolog	0.0015	0.0019	0.0017
Trypanosoma cruzi	cysteine peptidase, Clan CA, family C2, putative	0.0135	0.1433	0.2312
Brugia malayi	calpain 5	0.01	0.102	0.1008
Schistosoma mansoni	coup transcription factor	0.0278	0.3134	0.3127
Brugia malayi	putative neuropeptide receptor NPR1	0.0127	0.1344	0.1332
Echinococcus multilocularis	rhodopsin orphan GPCR	0.0127	0.1344	0.1405
Brugia malayi	hypothetical protein	0.023	0.2562	0.2552
Entamoeba histolytica	cysteine protease, putative	0.0016	0.0029	0.0103
Schistosoma mansoni	malic enzyme	0.0025	0.0139	0.013
Echinococcus granulosus	nuclear receptor 2DBD gamma	0.0278	0.3134	0.3285
Leishmania major	i/6 autoantigen-like protein	0.003	0.0194	0.0874
Brugia malayi	Dopamine receptor	0.0127	0.1344	0.1332
Loa Loa (eye worm)	hypothetical protein	0.0127	0.1344	0.1344
Schistosoma mansoni	nuclear receptor	0.0131	0.1394	0.1386
Loa Loa (eye worm)	hypothetical protein	0.0278	0.3134	0.3134
Trypanosoma cruzi	hypothetical protein, conserved	0.0071	0.0679	0.108
Leishmania major	apurinic/apyrimidinic endonuclease-redox protein	0.0038	0.0286	0.1359
Trichomonas vaginalis	importin beta-1, putative	0.0024	0.0125	0.0107
Trypanosoma brucei	malic enzyme	0.0025	0.0139	0.0674
Echinococcus granulosus	Nuclear hormone receptor HR96	0.0131	0.1394	0.1457
Echinococcus granulosus	cpg binding protein	0.0061	0.0559	0.0581
Schistosoma mansoni	rhodopsin-like orphan GPCR	0.0127	0.1344	0.1336
Schistosoma mansoni	cathepsin B-like peptidase (C01 family)	0.0016	0.0029	0.002
Leishmania major	calpain family cysteine protease-like protein	0.0035	0.0253	0.1184
Brugia malayi	G protein-coupled receptor	0.0127	0.1344	0.1332
Loa Loa (eye worm)	calpain	0.0135	0.1433	0.1433
Trypanosoma brucei	cysteine peptidase, Clan CA, family C2, putative	0.0035	0.0253	0.1272
Loa Loa (eye worm)	PAN domain-containing protein	0.0015	0.0013	0.0013
Brugia malayi	nuclear hormone receptor family member nhr-6	0.0131	0.1394	0.1382
Toxoplasma gondii	EFHC1, putative	0.003	0.0194	0.0949
Loa Loa (eye worm)	hypothetical protein	0.0127	0.1344	0.1344
Echinococcus granulosus	microtubule associated protein 2	0.0697	0.8087	0.8487
Loa Loa (eye worm)	hypothetical protein	0.0073	0.0708	0.0708
Onchocerca volvulus		0.0073	0.0708	0.2226
Trichomonas vaginalis	calmodulin-2, putative	0.003	0.0194	0.0176
Trichomonas vaginalis	malic enzyme, putative	0.0025	0.0139	0.012
Schistosoma mansoni	neuronal calcium sensor	0.003	0.0194	0.0185
Brugia malayi	Calmodulin-like protein	0.003	0.0194	0.0181
Echinococcus multilocularis	hepatocyte nuclear factor 4 alpha	0.0278	0.3134	0.3285
Brugia malayi	Papain family cysteine protease containing protein	0.0016	0.0029	0.0016
Brugia malayi	NAD-dependent malic enzyme, mitochondrial precursor, putative	0.0025	0.0139	0.0125
Loa Loa (eye worm)	hypothetical protein	0.0127	0.1344	0.1344
Giardia lamblia	Hypothetical protein	0.003	0.0199	0.0952
Loa Loa (eye worm)	MH2 domain-containing protein	0.0121	0.1267	0.1267
Leishmania major	calpain-like protein, putative,cysteine peptidase, Clan CA, family C2, putative	0.0035	0.0253	0.1184
Brugia malayi	Papain family cysteine protease containing protein	0.0016	0.0029	0.0016
Loa Loa (eye worm)	hypothetical protein	0.0147	0.158	0.158
Loa Loa (eye worm)	hypothetical protein	0.0335	0.3806	0.3806
Loa Loa (eye worm)	hypothetical protein	0.0127	0.1344	0.1344
Plasmodium falciparum	serine repeat antigen 9	0.0016	0.0029	0.0156
Trypanosoma cruzi	calpain-like cysteine peptidase, putative	0.0135	0.1433	0.2312
Trypanosoma brucei	hypothetical protein, conserved	0.003	0.0194	0.0965
Entamoeba histolytica	hypothetical protein	0.0036	0.027	0.251
Schistosoma mansoni	myosin regulatory light chain	0.0015	0.0019	0.001
Schistosoma mansoni	ran	0.0022	0.0099	0.009
Trypanosoma brucei	importin beta-1 subunit, putative	0.003	0.0192	0.0952
Plasmodium falciparum	cysteine proteinase falcipain 3	0.0016	0.0029	0.0156
Brugia malayi	Nuclear hormone receptor-like 1	0.0147	0.158	0.1569
Schistosoma mansoni	myosin regulatory light chain	0.0015	0.0019	0.001
Echinococcus multilocularis	fmrfamide receptor	0.0127	0.1344	0.1405
Brugia malayi	Nuclear hormone receptor E75	0.0131	0.1394	0.1382
Echinococcus granulosus	cathepsin b	0.0532	0.6135	0.6437
Echinococcus multilocularis	EF hand domain containing family member A2	0.003	0.0199	0.0203
Loa Loa (eye worm)	G-protein-linked acetylcholine receptor protein 2	0.0127	0.1344	0.1344
Loa Loa (eye worm)	hypothetical protein	0.0016	0.0029	0.0029
Entamoeba histolytica	cysteine proteinase, putative	0.0016	0.0029	0.0103
Plasmodium vivax	vivapain-2	0.0016	0.0029	0.0073
Entamoeba histolytica	calpain family cysteine protease, putative	0.0035	0.0253	0.2336
Brugia malayi	neuropeptide F receptor	0.0127	0.1344	0.1332
Mycobacterium ulcerans	beta-lactamase	0.0073	0.0708	0.0649
Schistosoma mansoni	neuropeptide f receptor 76f	0.0127	0.1344	0.1336
Leishmania major	calmodulin, putative	0.003	0.0194	0.0874
Echinococcus granulosus	g protein linked acetylcholine receptor gar 2a	0.0127	0.1344	0.1405
Onchocerca volvulus	Nuclear receptor subfamily 6 group A member 1 homolog	0.0131	0.1394	0.4424
Loa Loa (eye worm)	hypothetical protein	0.0127	0.1344	0.1344
Trypanosoma brucei	cytoskeleton-associated protein CAP5.5, putative	0.0035	0.0253	0.1272
Schistosoma mansoni	hypothetical protein	0.0036	0.027	0.0261
Trypanosoma brucei	importin beta-1 subunit, putative	0.003	0.0192	0.0952
Onchocerca volvulus		0.0016	0.0029	0.005
Echinococcus multilocularis	calbindin 32	0.003	0.0199	0.0203
Entamoeba histolytica	calmodulin, putative	0.003	0.0194	0.175
Loa Loa (eye worm)	hypothetical protein	0.0131	0.1394	0.1394
Giardia lamblia	Cathepsin B-like cysteine proteinase 3 precursor	0.0016	0.0029	0.0054
Plasmodium vivax	serine-repeat antigen 4 (SERA), putative	0.0016	0.0029	0.0073
Onchocerca volvulus		0.0127	0.1344	0.4264
Loa Loa (eye worm)	hypothetical protein	0.027	0.3038	0.3038
Schistosoma mansoni	intermediate filament proteins	0.0029	0.0184	0.0175
Mycobacterium ulcerans	hypothetical protein	0.0073	0.0708	0.0649
Brugia malayi	Myosin regulatory light chain 1	0.0015	0.0019	0.0005
Toxoplasma gondii	calcium-dependent protein kinase	0.003	0.0199	0.0977
Echinococcus granulosus	dna polymerase kappa	0.0021	0.0086	0.0084
Schistosoma mansoni	muscarinic acetylcholine (GAR) receptor	0.0127	0.1344	0.1336
Plasmodium vivax	serine-repeat antigen (SERA), putative	0.0016	0.0029	0.0073
Echinococcus multilocularis	G protein coupled 5 hydroxytryptamine receptor	0.0127	0.1344	0.1405
Schistosoma mansoni	cathepsin B-like peptidase (C01 family)	0.0016	0.0029	0.002
Plasmodium vivax	calcium-dependent protein kinase 3, putative	0.003	0.0194	0.124
Trichomonas vaginalis	Clan CA, family C1, cathepsin L-like cysteine peptidase	0.0016	0.0029	0.001
Loa Loa (eye worm)	calpain family protein 1	0.037	0.4218	0.4218
Loa Loa (eye worm)	nuclear receptor NHR-67	0.0131	0.1394	0.1394
Trichomonas vaginalis	esterase, putative	0.0073	0.0708	0.069
Trypanosoma brucei	DNA polymerase eta, putative	0.0021	0.0086	0.0401
Schistosoma mansoni	hypothetical protein	0.0071	0.0679	0.0671
Brugia malayi	tailless protein	0.0131	0.1394	0.1382
Leishmania major	calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative	0.0035	0.0253	0.1184
Trichomonas vaginalis	calmodulin, putative	0.003	0.0194	0.0176
Leishmania major	calmodulin-like protein	0.003	0.0194	0.0874
Schistosoma mansoni	ancient conserved domain protein 2 (cyclin m2)	0.0127	0.1344	0.1336
Trypanosoma brucei	DNA polymerase kappa, putative	0.0021	0.0086	0.0401
Schistosoma mansoni	nuclear hormone receptor nor-1/nor-2	0.0278	0.3134	0.3127
Brugia malayi	Cathepsin L-like precursor	0.0016	0.0029	0.0016
Mycobacterium tuberculosis	Conserved protein	0.0073	0.0708	0.1213
Schistosoma mansoni	hypothetical protein	0.0127	0.1344	0.1336
Trypanosoma cruzi	malic enzyme	0.0025	0.0139	0.0196
Trichomonas vaginalis	calpain, putative	0.0035	0.0253	0.0234
Onchocerca volvulus		0.0127	0.1344	0.4264
Loa Loa (eye worm)	hypothetical protein	0.0127	0.1344	0.1344
Trichomonas vaginalis	Clan CA, family C1, cathepsin L-like cysteine peptidase	0.0016	0.0029	0.001
Echinococcus multilocularis	nuclear factor of activated T cells 5	0.0053	0.0466	0.0483
Trypanosoma brucei	cysteine peptidase, Clan CA, family C1, Cathepsin L-like	0.0016	0.0029	0.01
Echinococcus granulosus	7tm_1 domain containing protein	0.0127	0.1344	0.1405
Mycobacterium tuberculosis	Conserved protein	0.0073	0.0708	0.1213
Leishmania major	calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative	0.0135	0.1433	0.7432
Leishmania major	DNA polymerase eta, putative	0.0021	0.0086	0.0304
Brugia malayi	hypothetical protein	0.0127	0.1344	0.1332
Mycobacterium ulcerans	malate dehydrogenase	0.0025	0.0139	0.0077
Echinococcus granulosus	mixed lineage leukemia protein mll	0.0014	0.0009	0.0003
Loa Loa (eye worm)	hypothetical protein	0.0127	0.1344	0.1344
Trichomonas vaginalis	ran, putative	0.0022	0.0099	0.008
Entamoeba histolytica	cysteine protease, putative	0.0016	0.0029	0.0103
Echinococcus granulosus	beta LACTamase domain containing family member	0.0073	0.0708	0.0737
Entamoeba histolytica	EF-hand calcium-binding domain containing protein	0.003	0.0194	0.175
Echinococcus granulosus	g protein coupled receptor	0.0127	0.1344	0.1405
Loa Loa (eye worm)	hypothetical protein	0.0131	0.1394	0.1394
Trypanosoma cruzi	malic enzyme	0.0025	0.0139	0.0196
Brugia malayi	cathepsin L-like precursor	0.0016	0.0029	0.0016
Schistosoma mansoni	calpain-7 (C02 family)	0.0135	0.1433	0.1425
Trypanosoma cruzi	Present in the outer mitochondrial membrane proteome 33	0.003	0.0194	0.0287
Trichomonas vaginalis	calmodulin, putative	0.0045	0.0373	0.0355
Schistosoma mansoni	ran	0.0022	0.0099	0.009
Brugia malayi	Nuclear hormone receptor family member nhr-19	0.0278	0.3134	0.3125
Mycobacterium tuberculosis	Probable lipase LipD	0.0073	0.0708	0.1213
Trypanosoma brucei	kinesin, putative	0.01	0.102	0.5295
Trypanosoma cruzi	DNA polymerase eta, putative	0.0021	0.0086	0.0111
Trichomonas vaginalis	Clan CA, family C1, cathepsin L-like cysteine peptidase	0.0016	0.0029	0.001
Onchocerca volvulus		0.003	0.0199	0.0596
Entamoeba histolytica	cysteine protease, putative	0.0016	0.0029	0.0103
Leishmania major	calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative	0.0035	0.0253	0.1184
Onchocerca volvulus	Neuropeptide F receptor homolog	0.0127	0.1344	0.4264
Entamoeba histolytica	hypothetical protein	0.0024	0.0125	0.1062
Loa Loa (eye worm)	neuropeptide F receptor	0.0127	0.1344	0.1344
Entamoeba histolytica	cysteine protease, putative	0.0016	0.0029	0.0103
Loa Loa (eye worm)	calmodulin-like protein	0.003	0.0194	0.0194
Loa Loa (eye worm)	G-protein coupled receptor	0.0127	0.1344	0.1344
Trichomonas vaginalis	Clan CA, family C1, cathepsin L-like cysteine peptidase	0.0016	0.0029	0.001
Echinococcus granulosus	histone lysine N methyltransferase MLL3	0.0014	0.0009	0.0003
Onchocerca volvulus	Nuclear receptor subfamily 6 group A member 1 homolog	0.0131	0.1394	0.4424
Giardia lamblia	Cathepsin B precursor	0.0176	0.1918	1
Loa Loa (eye worm)	hypothetical protein	0.037	0.4218	0.4218
Echinococcus granulosus	rhodopsin orphan GPCR	0.0127	0.1344	0.1405
Leishmania major	hypothetical protein, unknown function	0.0035	0.0253	0.1184
Leishmania major	calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative	0.0035	0.0253	0.1184
Echinococcus multilocularis	g protein coupled receptor	0.0127	0.1344	0.1405
Trypanosoma cruzi	calpain cysteine peptidase, putative	0.0135	0.1433	0.2312
Onchocerca volvulus		0.0127	0.1344	0.4264
Brugia malayi	hypothetical protein	0.0147	0.158	0.1569
Trypanosoma cruzi	cruzipain precursor, putative	0.0016	0.0029	0.0017
Mycobacterium ulcerans	DNA polymerase IV	0.0021	0.0086	0.0024
Leishmania major	calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative	0.0035	0.0253	0.1184
Trypanosoma brucei	NADP-dependent malic enzyme, cytosolic	0.0025	0.0139	0.0674
Trichomonas vaginalis	Clan CA, family C1, cathepsin L-like cysteine peptidase	0.0016	0.0029	0.001
Trypanosoma brucei	hypothetical protein, conserved	0.0073	0.0708	0.3659
Leishmania major	protein kinase, putative	0.003	0.0194	0.0874
Brugia malayi	Nuclear hormone receptor family member nhr-3	0.0278	0.3134	0.3125
Entamoeba histolytica	papain family cysteine protease domain containing protein	0.0016	0.0029	0.0103
Trichomonas vaginalis	Clan CA, family C2, calpain-like cysteine peptidase	0.0035	0.0253	0.0234
Brugia malayi	Hypothetical 52.5 kDa protein ZK945.1 in chromosome II, putative	0.0073	0.0708	0.0695
Echinococcus granulosus	thyrotropin releasing hormone receptor	0.0127	0.1344	0.1405
Loa Loa (eye worm)	glutaminase	0.0859	1	1
Trypanosoma cruzi	cysteine peptidase (N-terminal), putative	0.0016	0.0029	0.0017
Giardia lamblia	Hypothetical protein	0.0016	0.0029	0.0054
Trichomonas vaginalis	conserved hypothetical protein	0.0016	0.0029	0.001
Echinococcus multilocularis	dna polymerase kappa	0.0021	0.0086	0.0084
Trichomonas vaginalis	Clan CA, family C1, cathepsin L or K-like cysteine peptidase	0.0016	0.0029	0.001
Giardia lamblia	GTP-binding nuclear protein RAN/TC4	0.0022	0.0099	0.0421
Brugia malayi	calpain D	0.0035	0.0253	0.024
Brugia malayi	ImpB/MucB/SamB family protein	0.0021	0.0086	0.0073
Plasmodium vivax	serine-repeat antigen 4 (SERA)	0.0016	0.0029	0.0073
Trypanosoma brucei	I/6 autoantigen	0.003	0.0194	0.0965
Entamoeba histolytica	cysteine protease, putative	0.0016	0.0029	0.0103
Trypanosoma brucei	calpain-like protein, putative	0.0135	0.1433	0.7458
Plasmodium vivax	calpain, putative	0.0135	0.1433	1
Leishmania major	calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative	0.0135	0.1433	0.7432
Brugia malayi	Cathepsin L-like cysteine proteinase	0.0016	0.0029	0.0016
Echinococcus granulosus	neuropeptide receptor	0.0251	0.2804	0.2939
Loa Loa (eye worm)	hypothetical protein	0.0015	0.0019	0.0019
Schistosoma mansoni	peptide (FMRFamide/neurokinin-3)-like receptor	0.0127	0.1344	0.1336
Brugia malayi	calpain family protein 1	0.037	0.4218	0.421
Echinococcus granulosus	neuropeptide s receptor	0.0127	0.1344	0.1405
Schistosoma mansoni	opsin-like receptor	0.0127	0.1344	0.1336
Echinococcus granulosus	hepatocyte nuclear factor 4 alpha	0.0278	0.3134	0.3285
Brugia malayi	Papain family cysteine protease containing protein	0.0016	0.0029	0.0016
Schistosoma mansoni	retinoid-x-receptor (RXR)	0.0147	0.158	0.1572
Trichomonas vaginalis	malic enzyme, putative	0.0025	0.0139	0.012
Echinococcus granulosus	NADP dependent malic enzyme	0.0025	0.0139	0.0139
Schistosoma mansoni	reticulocalbin	0.003	0.0199	0.019
Brugia malayi	EF hand family protein	0.003	0.0194	0.0181
Schistosoma mansoni	amine GPCR	0.0127	0.1344	0.1336
Onchocerca volvulus		0.0016	0.0029	0.005
Echinococcus multilocularis	FTZ F1 alpha	0.0278	0.3134	0.3285
Loa Loa (eye worm)	hypothetical protein	0.0278	0.3134	0.3134
Giardia lamblia	Dipeptidyl-peptidase I precursor	0.0016	0.0029	0.0054
Schistosoma mansoni	dipeptidyl-peptidase I (C01 family)	0.0016	0.0029	0.002
Brugia malayi	Melatonin receptor type 1A	0.0127	0.1344	0.1332
Loa Loa (eye worm)	hypothetical protein	0.0016	0.0029	0.0029
Entamoeba histolytica	cysteine protease, putative	0.0016	0.0029	0.0103
Schistosoma mansoni	thyrotropin-releasing hormone receptor	0.0127	0.1344	0.1336
Schistosoma mansoni	lamin	0.0029	0.0184	0.0175
Brugia malayi	conserved hypotetical protein	0.0131	0.1394	0.1382
Trichomonas vaginalis	calmodulin, putative	0.003	0.0199	0.0181
Giardia lamblia	Cathepsin B precursor	0.0176	0.1918	1
Leishmania major	importin beta-1 subunit, putative	0.0024	0.0125	0.0509
Echinococcus multilocularis	calpain A	0.04	0.4577	0.4801
Schistosoma mansoni	subfamily C1A unassigned peptidase (C01 family)	0.0016	0.0029	0.002
Plasmodium vivax	AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative	0.0038	0.0286	0.1888
Trypanosoma brucei	cysteine peptidase, Clan CA, family C1, Cathepsin L-like	0.0016	0.0029	0.01
Echinococcus granulosus	tm gpcr rhodopsin	0.0127	0.1344	0.1405
Onchocerca volvulus		0.0131	0.1394	0.4424
Brugia malayi	EF hand family protein	0.003	0.0199	0.0186
Mycobacterium tuberculosis	Conserved protein	0.0073	0.0708	0.1213
Entamoeba histolytica	exodeoxyribonuclease III, putative	0.0038	0.0286	0.2665
Echinococcus granulosus	histone lysine N methyltransferase MLL3	0.0018	0.0051	0.0047
Trypanosoma cruzi	cysteine peptidase, Clan CA, family C2, putative	0.0035	0.0253	0.0382
Giardia lamblia	Encystation-specific protease	0.0016	0.0029	0.0054
Echinococcus multilocularis	g protein coupled receptor	0.0127	0.1344	0.1405
Echinococcus granulosus	geminin	0.0183	0.2002	0.2096
Echinococcus multilocularis	FTZ F1 nuclear receptor protein	0.0278	0.3134	0.3285
Trichomonas vaginalis	Crustacean calcium-binding protein, putative	0.003	0.0194	0.0176
Trypanosoma brucei	mitochondrial calcium uptake 1	0.003	0.0194	0.0965
Schistosoma mansoni	nuclear receptor	0.0131	0.1394	0.1386
Echinococcus multilocularis	musashi	0.0029	0.0184	0.0187
Plasmodium vivax	dipeptidyl aminopeptidase 1, putative	0.0016	0.0029	0.0073
Loa Loa (eye worm)	PAN domain-containing protein	0.0015	0.0013	0.0013
Trichomonas vaginalis	D-aminoacylase, putative	0.0073	0.0708	0.069
Onchocerca volvulus		0.0127	0.1344	0.4264
Trypanosoma cruzi	major cysteine proteinase, putative	0.0016	0.0029	0.0017
Echinococcus multilocularis	calpain 7 (C02 family)	0.0135	0.1433	0.1498
Echinococcus multilocularis	rhodopsin orphan GPCR	0.0127	0.1344	0.1405
Schistosoma mansoni	hypothetical protein	0.0047	0.0395	0.0387
Schistosoma mansoni	cathepsin F (C01 family)	0.0016	0.0029	0.002
Echinococcus multilocularis	alpha 1A adrenergic receptor	0.0127	0.1344	0.1405
Loa Loa (eye worm)	unidentified vitellogenin-linked transcript protein 6	0.0127	0.1344	0.1344
Loa Loa (eye worm)	hypothetical protein	0.0014	0.0006	0.0006
Toxoplasma gondii	histone lysine methyltransferase SET1	0.0109	0.1129	0.5858
Toxoplasma gondii	ABC1 family protein	0.0073	0.0708	0.3647
Trichomonas vaginalis	Clan CA, family C1, cathepsin L-like cysteine peptidase	0.0016	0.0029	0.001
Echinococcus multilocularis	histone lysine N methyltransferase MLL3	0.0018	0.0051	0.0047
Trypanosoma cruzi	calmodulin, putative	0.003	0.0194	0.0287
Trypanosoma cruzi	conserved protein	0.0035	0.0253	0.0382
Schistosoma mansoni	neuropeptide F-like receptor	0.0127	0.1344	0.1336
Brugia malayi	G-protein coupled receptor	0.0127	0.1344	0.1332
Trichomonas vaginalis	DNA polymerase IV / kappa, putative	0.0021	0.0086	0.0068
Echinococcus multilocularis	cysteine protease	0.0016	0.0029	0.0024
Trypanosoma cruzi	cysteine peptidase, Clan CA, family C2, putative	0.0135	0.1433	0.2312
Echinococcus multilocularis	g protein linked acetylcholine receptor gar 2a	0.0127	0.1344	0.1405
Echinococcus multilocularis	cathepsin L	0.0016	0.0029	0.0024
Schistosoma mansoni	neuronal calcium sensor	0.003	0.0194	0.0185
Entamoeba histolytica	cysteine proteinase 2	0.0016	0.0029	0.0103
Schistosoma mansoni	SmCL2-like peptidase (C01 family)	0.0016	0.0029	0.002
Brugia malayi	calcium-binding protein	0.003	0.0194	0.0181
Echinococcus multilocularis	Calcium binding protein	0.0015	0.0019	0.0013
Echinococcus multilocularis	histone lysine N methyltransferase MLL3	0.0014	0.0009	0.0003
Trypanosoma brucei	cysteine peptidase, Clan CA, family C1, Cathepsin L-like	0.0016	0.0029	0.01
Trypanosoma brucei	cysteine peptidase, Clan CA, family C1, Cathepsin L-like	0.0016	0.0029	0.01
Echinococcus granulosus	calpain	0.0135	0.1433	0.1498
Trichomonas vaginalis	Clan CA, family C1, cathepsin L-like cysteine peptidase	0.0016	0.0029	0.001
Trypanosoma cruzi	calpain-like cysteine peptidase, putative	0.0035	0.0253	0.0382
Echinococcus multilocularis	g protein coupled receptor	0.0127	0.1344	0.1405
Onchocerca volvulus	Cathepsin F homolog	0.0016	0.0029	0.005
Trypanosoma cruzi	I/6 autoantigen, putative	0.003	0.0194	0.0287
Brugia malayi	CXXC zinc finger family protein	0.0057	0.052	0.0508
Schistosoma mansoni	biogenic amine (octopamine/dopamine) receptor	0.0127	0.1344	0.1336
Echinococcus multilocularis	nuclear receptor 2DBD gamma	0.0278	0.3134	0.3285
Plasmodium vivax	serine-repeat antigen (SERA), putative	0.0016	0.0029	0.0073
Echinococcus multilocularis	rhodopsin orphan GPCR	0.0127	0.1344	0.1405
Brugia malayi	Protein kinase domain containing protein	0.0071	0.0679	0.0667
Trichomonas vaginalis	calcium binding protein, putative	0.0045	0.0373	0.0355
Plasmodium falciparum	cysteine proteinase falcipain 1	0.0016	0.0029	0.0156
Trypanosoma brucei	cysteine peptidase, Clan CA, family C1, Cathepsin L-like	0.0016	0.0029	0.01
Leishmania major	cysteine peptidase C (CPC),CPC cysteine peptidase, Clan CA, family C1, Cathepsin B-like	0.0176	0.1918	1
Brugia malayi	Cathepsin L-like precursor	0.0016	0.0029	0.0016
Loa Loa (eye worm)	hypothetical protein	0.0127	0.1344	0.1344
Trichomonas vaginalis	Clan CA, family C1, cathepsin L-like cysteine peptidase	0.0016	0.0029	0.001
Schistosoma mansoni	adenoreceptor	0.0127	0.1344	0.1336
Loa Loa (eye worm)	hypothetical protein	0.003	0.0194	0.0194
Schistosoma mansoni	calmodulin related calcium binding protein	0.003	0.0194	0.0185
Schistosoma mansoni	biogenic amine (dopamine) receptor	0.0127	0.1344	0.1336
Loa Loa (eye worm)	nuclear hormone receptor	0.0131	0.1394	0.1394
Echinococcus multilocularis	importin subunit beta 1	0.003	0.0192	0.0195
Trypanosoma cruzi	CAMK/CAMKL family protein kinase, putative	0.003	0.0194	0.0287
Loa Loa (eye worm)	hypothetical protein	0.0131	0.1394	0.1394
Schistosoma mansoni	alpha-1 adrenergic receptor	0.0127	0.1344	0.1336
Echinococcus granulosus	calpain 5	0.0135	0.1433	0.1498
Brugia malayi	nuclear hormone receptor	0.0131	0.1394	0.1382
Onchocerca volvulus		0.0127	0.1344	0.4264
Trypanosoma brucei	DNA polymerase kappa, putative	0.0021	0.0086	0.0401
Loa Loa (eye worm)	hypothetical protein	0.0127	0.1344	0.1344
Trichomonas vaginalis	calcium binding protein, putative	0.003	0.0194	0.0176
Plasmodium vivax	unspecified product	0.0016	0.0029	0.0073
Loa Loa (eye worm)	histone methyltransferase	0.0018	0.0051	0.0051
Trypanosoma brucei	DNA polymerase kappa, putative	0.0021	0.0086	0.0401
Trichomonas vaginalis	myosin light chain 1, putative	0.003	0.0194	0.0176
Giardia lamblia	Cathepsin B precursor	0.0016	0.0029	0.0054
Brugia malayi	Ligand-binding domain of nuclear hormone receptor family protein	0.0278	0.3134	0.3125
Trichomonas vaginalis	Clan CA, family C1, cathepsin L-like cysteine peptidase	0.0016	0.0029	0.001
Echinococcus granulosus	nuclear receptor 2DBD gamma	0.0131	0.1394	0.1457
Entamoeba histolytica	calcium binding family protein	0.003	0.0194	0.175
Loa Loa (eye worm)	TK/ROR protein kinase	0.0071	0.0679	0.0679
Trypanosoma cruzi	malic enzyme, putative	0.0025	0.0139	0.0196
Echinococcus granulosus	somatostatin receptor	0.0127	0.1344	0.1405
Echinococcus multilocularis	rhodopsin orphan GPCR	0.0127	0.1344	0.1405
Loa Loa (eye worm)	myosin regulatory light chain 1	0.0015	0.0019	0.0019
Echinococcus granulosus	cathepsin l cysteine peptidase	0.0016	0.0029	0.0024
Trypanosoma brucei	DNA polymerase kappa, putative	0.0021	0.0086	0.0401
Plasmodium vivax	serine-repeat antigen 3 (SERA)	0.0016	0.0029	0.0073
Entamoeba histolytica	calpain large subunit domain III containing protein	0.01	0.102	1
Trypanosoma cruzi	cysteine peptidase, putative	0.0016	0.0029	0.0017
Brugia malayi	ImpB/MucB/SamB family protein	0.0021	0.0086	0.0073
Plasmodium falciparum	GTP-binding nuclear protein RAN/TC4	0.0022	0.0099	0.1211
Trypanosoma brucei	cysteine peptidase, Clan CA, family C1, Cathepsin L-like	0.0016	0.0029	0.01
Toxoplasma gondii	centrin family protein	0.0015	0.0019	0.0028
Loa Loa (eye worm)	hypothetical protein	0.0127	0.1344	0.1344
Trypanosoma brucei	cysteine peptidase, Clan CA, family C1, Cathepsin L-like	0.0016	0.0029	0.01
Leishmania major	DNA polymerase kappa, putative	0.0021	0.0086	0.0304
Brugia malayi	Papain family cysteine protease containing protein	0.0016	0.0029	0.0016
Echinococcus granulosus	lamin	0.0029	0.0184	0.0187
Loa Loa (eye worm)	hypothetical protein	0.0029	0.0184	0.0184
Loa Loa (eye worm)	GTP-binding nuclear protein RAN/TC4	0.0022	0.0099	0.0099
Loa Loa (eye worm)	nuclear hormone receptor family member nhr-40	0.0278	0.3134	0.3134
Plasmodium vivax	serine-repeat antigen (SERA)	0.0016	0.0029	0.0073
Schistosoma mansoni	cathepsin B-like peptidase (C01 family)	0.0176	0.1918	0.191
Schistosoma mansoni	SmCL2-like peptidase (C01 family)	0.0016	0.0029	0.002
Schistosoma mansoni	biogenic amine receptor	0.0127	0.1344	0.1336
Schistosoma mansoni	calpain C (C02 family)	0.0135	0.1433	0.1425
Loa Loa (eye worm)	hypothetical protein	0.0127	0.1344	0.1344
Trypanosoma cruzi	DNA polymerase kappa, putative	0.0021	0.0086	0.0111
Echinococcus multilocularis	calcyphosin protein	0.0015	0.0019	0.0013
Loa Loa (eye worm)	hypothetical protein	0.0147	0.158	0.158
Plasmodium falciparum	serine repeat antigen 8	0.0016	0.0029	0.0156
Trypanosoma brucei	Calpain-like protein 1.2	0.0035	0.0253	0.1272
Schistosoma mansoni	family S12 unassigned peptidase (S12 family)	0.0073	0.0708	0.0699
Echinococcus multilocularis	dnaJ subfamily B	0.0819	0.9528	1
Schistosoma mansoni	histamine-responsive GPCR (AAF21638)	0.0127	0.1344	0.1336
Echinococcus multilocularis	7TM GPCR, rhodopsin	0.0127	0.1344	0.1405
Brugia malayi	larval opioid receptor	0.0127	0.1344	0.1332
Echinococcus multilocularis	neurocalcin	0.003	0.0194	0.0197
Plasmodium falciparum	serine repeat antigen 3	0.0016	0.0029	0.0156
Trypanosoma brucei	cysteine peptidase, Clan CA, family C1, Cathepsin L-like	0.0016	0.0029	0.01
Trichomonas vaginalis	calcium binding protein, putative	0.003	0.0194	0.0176
Echinococcus multilocularis	snurportin 1	0.0317	0.3591	0.3765
Loa Loa (eye worm)	nucleolar RNA-associated protein alpha	0.0317	0.3591	0.3591
Loa Loa (eye worm)	hypothetical protein	0.0131	0.1394	0.1394
Entamoeba histolytica	hypothetical protein, conserved	0.003	0.0199	0.1804
Schistosoma mansoni	thyroid hormone receptor	0.0278	0.3134	0.3127
Trypanosoma brucei	cysteine peptidase, Clan CA, family C1, Cathepsin L-like	0.0016	0.0029	0.01
Loa Loa (eye worm)	intermediate filament protein	0.0029	0.0184	0.0184
Trichomonas vaginalis	Clan CA, family C1, cathepsin L-like cysteine peptidase	0.0016	0.0029	0.001
Echinococcus granulosus	NADP dependent malic enzyme	0.0025	0.0139	0.0139
Entamoeba histolytica	cysteine protease, putative	0.0016	0.0029	0.0103
Brugia malayi	Nuclear hormone receptor family member nhr-25	0.0278	0.3134	0.3125
Echinococcus granulosus	tm gpcr rhodopsin	0.0127	0.1344	0.1405
Trichomonas vaginalis	Clan CA, family C1, cathepsin H-like cysteine peptidase	0.0016	0.0029	0.001
Trypanosoma brucei	Calpain-like protein 1.1	0.0035	0.0253	0.1272
Trypanosoma cruzi	cytoskeleton-associated protein CAP5.5, putative	0.0035	0.0253	0.0382
Toxoplasma gondii	kringle domain-containing protein	0.0071	0.0679	0.3498
Echinococcus multilocularis	programmed cell death protein	0.0045	0.0373	0.0385
Brugia malayi	Tachykinin-like peptides receptor 99D	0.0127	0.1344	0.1332
Trypanosoma brucei	cysteine peptidase, Clan CA, family C1, Cathepsin L-like	0.0016	0.0029	0.01
Trichomonas vaginalis	penicillin-binding protein, putative	0.0073	0.0708	0.069
Trichomonas vaginalis	Clan CA, family C2, calpain-like cysteine peptidase	0.0035	0.0253	0.0234
Echinococcus multilocularis	mixed lineage leukemia protein mll	0.0014	0.0009	0.0003
Brugia malayi	RE15519p	0.0127	0.1344	0.1332
Schistosoma mansoni	cathepsin S (C01 family)	0.0016	0.0029	0.002
Echinococcus granulosus	neurocalcin	0.003	0.0194	0.0197
Loa Loa (eye worm)	CXXC zinc finger family protein	0.0057	0.052	0.052
Onchocerca volvulus		0.0016	0.0029	0.005
Onchocerca volvulus		0.0127	0.1344	0.4264
Mycobacterium ulcerans	glutaminase	0.0859	1	1
Schistosoma mansoni	hypothetical protein	0.0317	0.3591	0.3585
Echinococcus granulosus	DNA apurinic or apyrimidinic site lyase	0.0038	0.0286	0.0293
Loa Loa (eye worm)	EF hand family protein	0.003	0.0194	0.0194
Loa Loa (eye worm)	hypothetical protein	0.0127	0.1344	0.1344
Schistosoma mansoni	hepatocyte nuclear factor 4-alpha (hnf-4-alpha)	0.0131	0.1394	0.1386
Schistosoma mansoni	hypothetical protein	0.0127	0.1344	0.1336
Brugia malayi	cathepsin Z-like cysteine proteinase	0.0016	0.0029	0.0016
Mycobacterium ulcerans	lipase LipD	0.0073	0.0708	0.0649
Trichomonas vaginalis	calcium binding proteins, putative	0.003	0.0194	0.0176
Schistosoma mansoni	importin beta-1	0.003	0.0192	0.0183
Entamoeba histolytica	grainin, putative	0.003	0.0199	0.1804
Trichomonas vaginalis	Clan CA, family C1, cathepsin B-like cysteine peptidase	0.0016	0.0029	0.001
Echinococcus granulosus	g protein linked acetylcholine receptor gar 2a	0.0127	0.1344	0.1405
Brugia malayi	Cathepsin L-like precursor	0.0016	0.0029	0.0016
Trypanosoma brucei	cysteine peptidase, putative	0.0035	0.0253	0.1272
Schistosoma mansoni	ecdysone-induced protein 78c (dr-78)	0.0147	0.158	0.1572
Trichomonas vaginalis	D-aminoacylase, putative	0.0073	0.0708	0.069
Echinococcus granulosus	NADP dependent malic enzyme	0.0025	0.0139	0.0139
Schistosoma mansoni	nuclear hormone receptor	0.0131	0.1394	0.1386
Trypanosoma cruzi	cysteine peptidase, Clan CA, family C2, putative	0.0035	0.0253	0.0382
Trichomonas vaginalis	Clan CA, family C1, cathepsin L or K-like cysteine peptidase	0.0016	0.0029	0.001
Schistosoma mansoni	family C2 unassigned peptidase (C02 family)	0.04	0.4572	0.4567
Brugia malayi	nuclear hormone receptor family member odr-7	0.0131	0.1394	0.1382
Loa Loa (eye worm)	follicle stimulating hormone receptor	0.0127	0.1344	0.1344
Echinococcus multilocularis	neuronal calcium sensor	0.003	0.0194	0.0197
Echinococcus granulosus	tachykinin peptides receptor 99D	0.0127	0.1344	0.1405
Loa Loa (eye worm)	hypothetical protein	0.0073	0.0708	0.0708
Plasmodium vivax	hypothetical protein, conserved	0.003	0.0199	0.1278
Brugia malayi	Neuronal calcium sensor family protein 1	0.0015	0.0019	0.0005
Toxoplasma gondii	centrin	0.003	0.0194	0.0949
Loa Loa (eye worm)	hypothetical protein	0.0131	0.1394	0.1394
Loa Loa (eye worm)	hypothetical protein	0.0015	0.0019	0.0019
Trypanosoma cruzi	centrin, putative	0.0045	0.0373	0.0579
Loa Loa (eye worm)	hypothetical protein	0.0131	0.1394	0.1394
Trichomonas vaginalis	Clan CA, family C1, cathepsin B-like cysteine peptidase	0.0016	0.0029	0.001
Loa Loa (eye worm)	hypothetical protein	0.0127	0.1344	0.1344
Brugia malayi	Serotonin/octopamine receptor family protein 7	0.0127	0.1344	0.1332
Echinococcus granulosus	calcyphosin protein	0.0015	0.0019	0.0013
Loa Loa (eye worm)	myosin Light Chain family member	0.0016	0.0024	0.0024
Onchocerca volvulus		0.0016	0.0029	0.005
Brugia malayi	cathepsin L-like cysteine proteinase	0.0016	0.0029	0.0016
Leishmania major	centrin, putative,caltractin, putative	0.003	0.0194	0.0874
Echinococcus multilocularis	geminin	0.0183	0.2002	0.2096
Loa Loa (eye worm)	hypothetical protein	0.0127	0.1344	0.1344
Brugia malayi	GTP-binding nuclear protein RAN/TC4	0.0022	0.0099	0.0086
Trypanosoma brucei	cysteine peptidase, Clan CA, family C1, Cathepsin L-like	0.0016	0.0029	0.01
Brugia malayi	Cathepsin L-like precursor	0.0016	0.0029	0.0016
Entamoeba histolytica	cysteine protease, putative	0.0016	0.0029	0.0103
Trichomonas vaginalis	conserved hypothetical protein	0.003	0.0194	0.0176
Plasmodium vivax	unspecified product	0.0016	0.0029	0.0073
Schistosoma mansoni	mitochondrial solute carrier	0.003	0.0194	0.0185
Echinococcus granulosus	glutamate NMDA receptor subunit	0.0062	0.0572	0.0594
Loa Loa (eye worm)	NADP-malic enzyme	0.0019	0.0061	0.0061
Echinococcus multilocularis	cathepsin l cysteine peptidase	0.0016	0.0029	0.0024
Brugia malayi	Intermediate filament tail domain containing protein	0.0029	0.0184	0.0171
Toxoplasma gondii	EF hand domain-containing protein	0.0015	0.0019	0.0028
Schistosoma mansoni	amine GPCR	0.0127	0.1344	0.1336
Echinococcus multilocularis	Basic leucine zipper (bZIP) transcription	0.0036	0.027	0.0277
Loa Loa (eye worm)	hypothetical protein	0.0131	0.1394	0.1394
Echinococcus multilocularis	EF HAND 1, calcium binding site	0.003	0.0194	0.0197
Trichomonas vaginalis	Clan CA, family C1, cathepsin L, S or H-like cysteine peptidase	0.0016	0.0029	0.001
Schistosoma mansoni	retinoic acid receptor RXR	0.0278	0.3134	0.3127
Schistosoma mansoni	amine GPCR	0.0127	0.1344	0.1336
Giardia lamblia	Cysteine protease	0.0016	0.0029	0.0054
Echinococcus granulosus	FTZ F1 nuclear receptor protein	0.0278	0.3134	0.3285
Loa Loa (eye worm)	hypothetical protein	0.0147	0.158	0.158
Trypanosoma brucei	DNA polymerase kappa, putative	0.0021	0.0086	0.0401
Loa Loa (eye worm)	hypothetical protein	0.0071	0.0679	0.0679
Schistosoma mansoni	zinc finger protein	0.0131	0.1394	0.1386
Plasmodium vivax	GTP-binding nuclear protein RAN/TC4, putative	0.0022	0.0099	0.0566
Brugia malayi	hypothetical protein	0.0131	0.1394	0.1382
Brugia malayi	hypothetical protein	0.0127	0.1344	0.1332
Brugia malayi	ecdysteroid receptor	0.0278	0.3134	0.3125
Schistosoma mansoni	neuronal calcium sensor	0.003	0.0194	0.0185
Schistosoma mansoni	terminal deoxycytidyl transferase	0.0021	0.0086	0.0077
Plasmodium vivax	serine-repeat antigen 2 (SERA)	0.0016	0.0029	0.0073
Echinococcus granulosus	calumenin	0.003	0.0199	0.0203
Trichomonas vaginalis	malic enzyme, putative	0.0025	0.0139	0.012
Leishmania major	cytoskeleton-associated protein CAP5.5, putative,cysteine peptidase, Clan CA, family C2, putative	0.0035	0.0253	0.1184
Echinococcus granulosus	calpain A	0.04	0.4577	0.4801
Brugia malayi	hypothetical protein	0.0131	0.1394	0.1382
Trichomonas vaginalis	calcineurin B subunit, putative	0.003	0.0194	0.0176
Echinococcus granulosus	terminal deoxycytidyl transferase rev1	0.0021	0.0086	0.0084
Loa Loa (eye worm)	hypothetical protein	0.0278	0.3134	0.3134
Leishmania major	GTP-binding protein, putative	0.0022	0.0099	0.0369
Loa Loa (eye worm)	hypothetical protein	0.0127	0.1344	0.1344
Echinococcus multilocularis	tm gpcr rhodopsin gpcr rhodopsin superfamily	0.0127	0.1344	0.1405
Giardia lamblia	Cathepsin L precursor	0.0016	0.0029	0.0054
Onchocerca volvulus		0.0127	0.1344	0.4264
Loa Loa (eye worm)	hypothetical protein	0.0278	0.3134	0.3134
Trypanosoma brucei	glucosamine 6-phosphate n-acetyltransferase	0.0035	0.0253	0.1272
Loa Loa (eye worm)	hypothetical protein	0.0015	0.0013	0.0013
Giardia lamblia	Cysteine protease	0.0016	0.0029	0.0054
Trypanosoma brucei	cysteine peptidase, Clan CA, family C2, putative	0.0135	0.1433	0.7458
Brugia malayi	Nuclear hormone receptor-like 1	0.0147	0.158	0.1569
Schistosoma mansoni	neuronal calcium sensor	0.003	0.0194	0.0185
Trichomonas vaginalis	Clan CA, family C1, cathepsin L or H-like cysteine peptidase	0.0016	0.0029	0.001
Trypanosoma cruzi	cysteine proteinase, putative	0.0016	0.0029	0.0017
Entamoeba histolytica	cysteine protease, putative	0.0016	0.0029	0.0103
Echinococcus granulosus	dnaJ subfamily B	0.0819	0.9528	1
Loa Loa (eye worm)	hypothetical protein	0.0127	0.1344	0.1344
Echinococcus granulosus	Nuclear hormone receptor family member nhr 41	0.0278	0.3134	0.3285
Loa Loa (eye worm)	cytoplasmic intermediate filament protein	0.0016	0.0025	0.0025
Loa Loa (eye worm)	fibroinase	0.0016	0.0029	0.0029
Brugia malayi	nuclear receptor NHR-67	0.0131	0.1394	0.1382
Loa Loa (eye worm)	transcription factor SMAD2	0.0121	0.1267	0.1267
Trypanosoma cruzi	CAMK/CAMKL family protein kinase, putative	0.003	0.0194	0.0287
Loa Loa (eye worm)	G-protein coupled receptor	0.0127	0.1344	0.1344
Echinococcus granulosus	nuclear receptor subfamily 4 group A	0.0131	0.1394	0.1457
Schistosoma mansoni	rhodopsin-like orphan GPCR	0.0127	0.1344	0.1336
Loa Loa (eye worm)	nuclear hormone receptor family member nhr-14	0.0278	0.3134	0.3134
Onchocerca volvulus		0.0127	0.1344	0.4264
Trypanosoma brucei	DNA polymerase kappa, putative	0.0021	0.0086	0.0401
Mycobacterium tuberculosis	Probable [NAD] dependent malate oxidoreductase Mez (malic enzyme) (NAD-malic enzyme) (malate dehydrogenase (oxaloacetate decarbo	0.0025	0.0139	0.0143
Toxoplasma gondii	cathepsin CPC2	0.0016	0.0029	0.0082
Brugia malayi	Nuclear hormone receptor family member nhr-40	0.0278	0.3134	0.3125
Schistosoma mansoni	cathepsin B-like peptidase (C01 family)	0.0016	0.0029	0.002
Leishmania major	malic enzyme, putative	0.0025	0.0139	0.058
Plasmodium falciparum	serine repeat antigen 5	0.0016	0.0029	0.0156
Loa Loa (eye worm)	hypothetical protein	0.0073	0.0708	0.0708
Echinococcus multilocularis	fmrfamide receptor	0.0127	0.1344	0.1405
Schistosoma mansoni	cathepsin B-like peptidase (C01 family)	0.0016	0.0029	0.002
Trichomonas vaginalis	Clan CA, family C1, papain-like cysteine peptidase	0.0016	0.0029	0.001
Echinococcus granulosus	calbindin 32	0.003	0.0199	0.0203
Giardia lamblia	Cathepsin L precursor	0.0016	0.0029	0.0054
Loa Loa (eye worm)	hypothetical protein	0.0235	0.2626	0.2626
Echinococcus multilocularis	programmed cell death protein	0.0045	0.0373	0.0385
Trichomonas vaginalis	Clan CA, family C1, cathepsin F-like cysteine peptidase	0.0016	0.0029	0.001
Loa Loa (eye worm)	hypothetical protein	0.0127	0.1344	0.1344
Loa Loa (eye worm)	hypothetical protein	0.0127	0.1344	0.1344
Giardia lamblia	Cysteine protease	0.0016	0.0029	0.0054
Echinococcus granulosus	GTP binding nuclear protein Ran	0.0022	0.0099	0.0097
Echinococcus granulosus	cathepsin L cysteine proteinase	0.0016	0.0029	0.0024
Trypanosoma cruzi	calpain-like cysteine peptidase, putative	0.0035	0.0253	0.0382
Toxoplasma gondii	calmodulin, putative	0.0015	0.0019	0.0028
Echinococcus granulosus	rhodopsin orphan GPCR	0.0127	0.1344	0.1405
Entamoeba histolytica	cysteine proteinase 1, putative	0.0016	0.0029	0.0103
Loa Loa (eye worm)	intermediate filament tail domain-containing protein	0.0029	0.0184	0.0184
Loa Loa (eye worm)	nuclear hormone receptor family member nhr-49	0.0278	0.3134	0.3134
Loa Loa (eye worm)	steroid hormone receptor	0.0278	0.3134	0.3134
Mycobacterium tuberculosis	Probable exodeoxyribonuclease III protein XthA (exonuclease III) (EXO III) (AP endonuclease VI)	0.0038	0.0286	0.0419
Loa Loa (eye worm)	hypothetical protein	0.0127	0.1344	0.1344
Schistosoma mansoni	amine GPCR	0.0127	0.1344	0.1336
Trichomonas vaginalis	glutaminase, putative	0.0859	1	1
Plasmodium vivax	importin-beta 2, putative	0.003	0.0192	0.1222
Onchocerca volvulus		0.0127	0.1344	0.4264
Trypanosoma cruzi	DNA polymerase kappa, putative	0.0021	0.0086	0.0111
Brugia malayi	Cathepsin L-like precursor	0.0016	0.0029	0.0016
Trichomonas vaginalis	malic enzyme, putative	0.0019	0.0061	0.0043
Loa Loa (eye worm)	hypothetical protein	0.0127	0.1344	0.1344
Mycobacterium leprae	conserved hypothetical protein	0.0073	0.0708	0.5
Brugia malayi	gonadotropin-releasing hormone receptor 2	0.0127	0.1344	0.1332
Echinococcus granulosus	nuclear receptor 2DBD gamma	0.0278	0.3134	0.3285
Toxoplasma gondii	GTP-binding nuclear protein ran/tc4	0.0022	0.0099	0.0448
Echinococcus granulosus	FTZ F1 alpha	0.0278	0.3134	0.3285
Echinococcus multilocularis	sarcoplasmic calcium binding protein	0.003	0.0194	0.0197
Echinococcus multilocularis	GTP binding nuclear protein Ran	0.0022	0.0099	0.0097
Onchocerca volvulus		0.0016	0.0029	0.005
Trichomonas vaginalis	calmodulin, putative	0.003	0.0194	0.0176
Loa Loa (eye worm)	hypothetical protein	0.0073	0.0708	0.0708
Schistosoma mansoni	lamin	0.0029	0.0184	0.0175
Trypanosoma brucei	hypothetical protein	0.0035	0.0253	0.1272
Echinococcus multilocularis	tm gpcr rhodopsin gpcr rhodopsin superfamily	0.0127	0.1344	0.1405
Leishmania major	calcineurin B subunit, putative	0.003	0.0194	0.0874
Brugia malayi	Cathepsin L-like precursor	0.0016	0.0029	0.0016
Trypanosoma cruzi	cysteine peptidase, clan CA, family C1, cathepsin L-like, putative	0.0016	0.0029	0.0017
Entamoeba histolytica	hypothetical protein	0.0036	0.027	0.251
Trichomonas vaginalis	Clan CA, family C1, cathepsin L-like cysteine peptidase	0.0016	0.0029	0.001
Toxoplasma gondii	calmodulin CAM1	0.003	0.0199	0.0977
Toxoplasma gondii	HEAT repeat-containing protein	0.003	0.0192	0.0936
Trichomonas vaginalis	Clan CA, family C2, calpain-like cysteine peptidase	0.0035	0.0253	0.0234
Loa Loa (eye worm)	papain family cysteine protease containing protein	0.0016	0.0029	0.0029
Brugia malayi	programmed cell death protein 6	0.003	0.0194	0.0181
Giardia lamblia	Cathepsin B precursor	0.0016	0.0029	0.0054
Schistosoma mansoni	centrin-related	0.003	0.0194	0.0185
Onchocerca volvulus		0.0127	0.1344	0.4264
Brugia malayi	RasGEF domain containing protein	0.0015	0.0019	0.0005
Mycobacterium tuberculosis	Possible penicillin-binding protein	0.0469	0.5384	1
Trypanosoma cruzi	cysteine peptidase, Clan CA, family C2, putative	0.0035	0.0253	0.0382
Schistosoma mansoni	peptide (FMRFamide/somatostatin)-like receptor	0.0127	0.1344	0.1336
Onchocerca volvulus	Bile acid receptor homolog	0.0278	0.3134	1
Brugia malayi	Serotonin receptor	0.0127	0.1344	0.1332
Trichomonas vaginalis	Clan CA, family C1, papain-like cysteine peptidase	0.0016	0.0029	0.001
Trypanosoma cruzi	I/6 autoantigen, putative	0.003	0.0194	0.0287
Echinococcus granulosus	calpain 7 C02 family	0.0135	0.1433	0.1498
Echinococcus multilocularis	Nuclear hormone receptor HR96	0.0131	0.1394	0.1457
Loa Loa (eye worm)	nuclear receptor nhr-7B	0.0131	0.1394	0.1394
Echinococcus granulosus	EF hand domain containing family member A2	0.003	0.0194	0.0197
Schistosoma mansoni	transcription factor LCR-F1	0.0036	0.027	0.0261
Loa Loa (eye worm)	cysteine proteinase cathepsin Z	0.0016	0.0029	0.0029
Echinococcus granulosus	biogenic amine 5HT receptor	0.0372	0.4241	0.4448
Echinococcus granulosus	calmodulin	0.003	0.0194	0.0197
Echinococcus multilocularis	rhodopsin orphan GPCR	0.0127	0.1344	0.1405
Loa Loa (eye worm)	hypothetical protein	0.0127	0.1344	0.1344
Loa Loa (eye worm)	hypothetical protein	0.0015	0.0013	0.0013
Toxoplasma gondii	centrin, putative	0.003	0.0194	0.0949
Giardia lamblia	Cathepsin L precursor	0.0016	0.0029	0.0054
Echinococcus granulosus	neuropeptide receptor	0.0127	0.1344	0.1405
Schistosoma mansoni	cpg binding protein	0.0057	0.052	0.0512
Echinococcus multilocularis	COUP TF:Svp nuclear hormone receptor	0.0278	0.3134	0.3285
Leishmania major	calmodulin-like protein	0.003	0.0194	0.0874
Onchocerca volvulus	Steroid hormone receptor family member cnr14 homolog	0.0278	0.3134	1
Entamoeba histolytica	cysteine protease, putative	0.0016	0.0029	0.0103
Trypanosoma cruzi	calpain-like cysteine peptidase, putative	0.0135	0.1433	0.2312
Echinococcus granulosus	thyroid hormone receptor alpha	0.0131	0.1394	0.1457
Giardia lamblia	Malic enzyme	0.0025	0.0139	0.0631
Echinococcus multilocularis	cathepsin l cysteine peptidase	0.0016	0.0029	0.0024
Brugia malayi	hypothetical protein	0.0127	0.1344	0.1332
Brugia malayi	Unidentified vitellogenin-linked transcript protein 6, putative	0.0127	0.1344	0.1332
Loa Loa (eye worm)	hypothetical protein	0.0127	0.1344	0.1344
Onchocerca volvulus		0.0015	0.0019	0.0017
Schistosoma mansoni	cathepsin B (C01 family)	0.0016	0.0029	0.002
Entamoeba histolytica	cysteine protease, putative	0.0016	0.0029	0.0103
Echinococcus multilocularis	cathepsin b	0.0532	0.6135	0.6437
Trypanosoma cruzi	calpain-like cysteine peptidase, putative	0.0035	0.0253	0.0382
Trichomonas vaginalis	Clan CA, family C1, papain-like cysteine peptidase	0.0016	0.0029	0.001
Schistosoma mansoni	ef hand domain family member A2	0.003	0.0194	0.0185
Brugia malayi	beta-lactamase family protein	0.0073	0.0708	0.0695
Trichomonas vaginalis	Clan CA, family C2, calpain-like cysteine peptidase	0.0035	0.0253	0.0234
Leishmania major	calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative	0.0035	0.0253	0.1184
Schistosoma mansoni	hypothetical protein	0.003	0.0194	0.0185
Giardia lamblia	Cathepsin L-like protease	0.0016	0.0029	0.0054
Loa Loa (eye worm)	hypothetical protein	0.0127	0.1344	0.1344
Entamoeba histolytica	calcium-binding protein, putative	0.003	0.0194	0.175
Echinococcus multilocularis	cysteine protease	0.0016	0.0029	0.0024
Echinococcus granulosus	neuronal calcium sensor	0.003	0.0194	0.0197
Trichomonas vaginalis	centrin, putative	0.003	0.0194	0.0176
Echinococcus granulosus	nuclear factor of activated T cells 5	0.0053	0.0466	0.0483
Onchocerca volvulus		0.003	0.0194	0.0579
Onchocerca volvulus		0.0073	0.0708	0.2226
Leishmania major	centrin, putative	0.003	0.0194	0.0874
Loa Loa (eye worm)	hypothetical protein	0.0127	0.1344	0.1344
Loa Loa (eye worm)	hypothetical protein	0.003	0.0194	0.0194
Schistosoma mansoni	cathepsin B-like peptidase (C01 family)	0.0532	0.6135	0.6132
Trichomonas vaginalis	calmodulin, putative	0.003	0.0194	0.0176
Echinococcus granulosus	rhodopsin orphan GPCR	0.0127	0.1344	0.1405
Trypanosoma brucei	Calpain-like protein 2	0.0035	0.0253	0.1272
Loa Loa (eye worm)	hypothetical protein	0.0016	0.0029	0.0029
Trichomonas vaginalis	calmodulin, putative	0.003	0.0194	0.0176
Giardia lamblia	Cathepsin B precursor	0.0016	0.0029	0.0054
Brugia malayi	Nuclear hormone receptor family member nhr-41	0.0278	0.3134	0.3125
Schistosoma mansoni	nuclear hormone receptor	0.0278	0.3134	0.3127
Echinococcus granulosus	hypothetical protein	0.0127	0.1344	0.1405
Trypanosoma brucei	Calpain-like protein CALP1.3	0.0035	0.0253	0.1272
Brugia malayi	cathepsin Z-like cysteine proteinase	0.0016	0.0029	0.0016
Trichomonas vaginalis	Clan CA, family C1, cathepsin L-like cysteine peptidase	0.0016	0.0029	0.001
Loa Loa (eye worm)	nuclear hormone receptor family member nhr-41	0.0278	0.3134	0.3134
Brugia malayi	nuclear receptor subfamily 1, group D, member 1, putative	0.0131	0.1394	0.1382
Echinococcus multilocularis	neuropeptide FF receptor 2	0.0127	0.1344	0.1405
Onchocerca volvulus	Malic enzyme homolog	0.0025	0.0139	0.0401
Loa Loa (eye worm)	hypothetical protein	0.0127	0.1344	0.1344
Mycobacterium leprae	Probable lipase LipE	0.0073	0.0708	0.5
Echinococcus granulosus	allatostatin A receptor	0.0127	0.1344	0.1405
Entamoeba histolytica	cysteine protease, putative	0.0016	0.0029	0.0103
Echinococcus multilocularis	rhodopsin orphan GPCR	0.0127	0.1344	0.1405
Plasmodium vivax	dipeptidyl aminopeptidase 2, putative	0.0016	0.0029	0.0073
Loa Loa (eye worm)	hypothetical protein	0.0127	0.1344	0.1344
Plasmodium vivax	dipeptidyl aminopeptidase 3, putative	0.0016	0.0029	0.0073
Mycobacterium tuberculosis	Conserved hypothetical protein	0.0021	0.0086	0.0045
Brugia malayi	cathepsin F-like cysteine proteinase	0.0016	0.0029	0.0016
Loa Loa (eye worm)	hypothetical protein	0.0015	0.0013	0.0013
Trypanosoma brucei	cysteine peptidase, Clan CA, family C2, putative	0.0035	0.0253	0.1272
Brugia malayi	nuclear receptor NHR-88	0.0278	0.3134	0.3125
Onchocerca volvulus		0.0016	0.0029	0.005
Mycobacterium tuberculosis	Possible conserved lipoprotein LpqK	0.0073	0.0708	0.1213
Schistosoma mansoni	Sarcoplasmic calcium-binding protein (SCP).	0.003	0.0194	0.0185
Schistosoma mansoni	DNA polymerase eta	0.0021	0.0086	0.0077
Onchocerca volvulus		0.0278	0.3134	1
Schistosoma mansoni	hypothetical protein	0.0035	0.0253	0.0244
Trypanosoma cruzi	cysteine peptidase, Clan CA, family C2, putative	0.0035	0.0253	0.0382
Echinococcus multilocularis	neuropeptide receptor	0.0251	0.2804	0.2939
Trichomonas vaginalis	Clan CA, family C1, papain-like cysteine peptidase	0.0016	0.0029	0.001
Trichomonas vaginalis	malic enzyme, putative	0.0025	0.0139	0.012
Loa Loa (eye worm)	hypothetical protein	0.0035	0.0253	0.0253
Loa Loa (eye worm)	neuropeptide F receptor	0.0127	0.1344	0.1344
Trypanosoma brucei	calmodulin, putative	0.003	0.0199	0.0993
Entamoeba histolytica	cysteine proteinase, putative	0.0016	0.0029	0.0103
Echinococcus multilocularis	EF hand domain containing family member A2	0.003	0.0194	0.0197
Onchocerca volvulus		0.0016	0.0029	0.005
Echinococcus multilocularis	dro:myosuppressin receptor	0.0127	0.1344	0.1405
Loa Loa (eye worm)	hypothetical protein	0.0016	0.0029	0.0029
Schistosoma mansoni	cathepsin F (C01 family)	0.0016	0.0029	0.002
Echinococcus multilocularis	terminal deoxycytidyl transferase rev1	0.0021	0.0086	0.0084
Schistosoma mansoni	steroid hormone receptor ad4bp	0.0278	0.3134	0.3127
Echinococcus granulosus	neuropeptide Y receptor	0.0127	0.1344	0.1405
Schistosoma mansoni	rab geranylgeranyl transferase alpha subunit	0.0021	0.0086	0.0077
Giardia lamblia	Cathepsin L precursor	0.0016	0.0029	0.0054
Loa Loa (eye worm)	hypothetical protein	0.0127	0.1344	0.1344
Giardia lamblia	Cathepsin L precursor	0.0016	0.0029	0.0054
Plasmodium falciparum	serine repeat antigen 1	0.0016	0.0029	0.0156
Trypanosoma cruzi	centrin-3	0.0045	0.0373	0.0579
Entamoeba histolytica	cysteine protease, putative	0.0016	0.0029	0.0103
Schistosoma mansoni	FTZ-F1 nuclear receptor-like protein	0.0278	0.3134	0.3127
Trypanosoma brucei	GTP-binding nuclear protein rtb2, putative	0.0022	0.0099	0.0465
Echinococcus multilocularis	nuclear receptor nhr 48	0.0131	0.1394	0.1457
Echinococcus multilocularis	NADP dependent malic enzyme	0.0025	0.0139	0.0139
Brugia malayi	exodeoxyribonuclease III family protein	0.0038	0.0286	0.0273
Trichomonas vaginalis	malic enzyme, putative	0.0025	0.0139	0.012
Echinococcus multilocularis	Myosin regulatory light chain	0.0015	0.0019	0.0013
Brugia malayi	Kringle domain containing protein	0.0071	0.0679	0.0667
Schistosoma mansoni	SmCB2 peptidase (C01 family)	0.0532	0.6135	0.6132
Trypanosoma brucei	DNA polymerase IV, putative	0.0021	0.0086	0.0401
Plasmodium falciparum	calpain	0.0035	0.0253	0.3541
Trypanosoma brucei	unspecified product	0.0021	0.0086	0.0401
Trichomonas vaginalis	penicillin-binding protein, putative	0.0073	0.0708	0.069
Trypanosoma cruzi	cysteine peptidase C (CPC), putative	0.0532	0.6135	1
Plasmodium falciparum	serine repeat antigen 7	0.0016	0.0029	0.0156
Onchocerca volvulus		0.0016	0.0029	0.005
Echinococcus granulosus	7TM GPCR rhodopsin	0.0127	0.1344	0.1405
Trypanosoma cruzi	hypothetical protein, conserved	0.0073	0.0708	0.1127
Onchocerca volvulus		0.0073	0.0708	0.2226
Echinococcus granulosus	serotonin receptor	0.0127	0.1344	0.1405
Brugia malayi	G-protein-linked acetylcholine receptor protein 2, putative	0.0127	0.1344	0.1332
Trypanosoma cruzi	importin beta-1 subunit, putative	0.0024	0.0125	0.0174
Trypanosoma cruzi	cysteine peptidase, putative	0.0016	0.0029	0.0017
Trypanosoma cruzi	cysteine peptidase, Clan CA, family C2, putative	0.0035	0.0253	0.0382
Leishmania major	programmed cell death 6 protein-like protein	0.003	0.0194	0.0874
Echinococcus granulosus	retinoic acid receptor rxr beta a	0.0278	0.3134	0.3285
Trypanosoma cruzi	cysteine proteinase, putative	0.0016	0.0029	0.0017
Leishmania major	calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative	0.0035	0.0253	0.1184
Schistosoma mansoni	neuropeptide receptor	0.0127	0.1344	0.1336
Schistosoma mansoni	rhodopsin-like orphan GPCR	0.0127	0.1344	0.1336
Trichomonas vaginalis	Clan CA, family C1, cathepsin L-like cysteine peptidase	0.0016	0.0029	0.001
Brugia malayi	calpain family protein 1	0.037	0.4218	0.421
Loa Loa (eye worm)	hypothetical protein	0.0016	0.0029	0.0029
Echinococcus granulosus	orexin receptor type 2	0.0127	0.1344	0.1405
Echinococcus granulosus	rhodopsin orphan GPCR	0.0127	0.1344	0.1405
Trichomonas vaginalis	Clan CA, family C2, calpain-like cysteine peptidase	0.0035	0.0253	0.0234
Loa Loa (eye worm)	5-hydroxytryptamine 2C receptor	0.0127	0.1344	0.1344
Echinococcus granulosus	cathepsin l1	0.0016	0.0029	0.0024
Schistosoma mansoni	neuropeptide receptor	0.0127	0.1344	0.1336
Trichomonas vaginalis	Clan CA, family C1, papain-like cysteine peptidase	0.0016	0.0029	0.001
Onchocerca volvulus	Cathepsin L homolog	0.0016	0.0029	0.005
Schistosoma mansoni	reticulocalbin	0.003	0.0194	0.0185
Trypanosoma brucei	apurinic/apyrimidinic endonuclease, putative	0.0038	0.0286	0.1445
Onchocerca volvulus		0.0127	0.1344	0.4264
Echinococcus multilocularis	Glutamate receptor, ionotropic kainate 3	0.0026	0.0149	0.015
Schistosoma mansoni	calpain (C02 family)	0.0135	0.1433	0.1425
Trypanosoma cruzi	malic enzyme, putative	0.0025	0.0139	0.0196
Echinococcus multilocularis	cpg binding protein	0.0061	0.0559	0.0581
Trichomonas vaginalis	Clan CA, family C1, papain-like cysteine peptidase	0.0016	0.0029	0.001
Toxoplasma gondii	troponin c, isotype gamma, putative	0.003	0.0194	0.0949
Echinococcus multilocularis	rhodopsin orphan GPCR	0.0127	0.1344	0.1405
Echinococcus granulosus	neuropeptide receptor A26	0.0127	0.1344	0.1405
Echinococcus multilocularis	nuclear receptor subfamily 4 group A	0.0131	0.1394	0.1457
Brugia malayi	Nuclear hormone receptor-like 1	0.0278	0.3134	0.3125
Trichomonas vaginalis	Clan CA, family C1, cathepsin L-like cysteine peptidase	0.0016	0.0029	0.001
Trichomonas vaginalis	malic enzyme, putative	0.0025	0.0139	0.012
Echinococcus granulosus	Calcium binding protein	0.0015	0.0019	0.0013
Brugia malayi	RNA, U transporter 1	0.0084	0.0839	0.0827
Entamoeba histolytica	cysteine proteinase, putative	0.0016	0.0029	0.0103
Onchocerca volvulus	Protein ultraspiracle homolog	0.0278	0.3134	1
Brugia malayi	nuclear receptor RXR	0.0147	0.158	0.1569
Brugia malayi	Nuclear hormone receptor E75	0.0131	0.1394	0.1382
Schistosoma mansoni	calpain-2 (C02 family)	0.0035	0.0253	0.0244
Echinococcus granulosus	pyroglutamylated rfamide peptide receptor	0.0127	0.1344	0.1405
Echinococcus multilocularis	tm gpcr rhodopsin gpcr rhodopsin superfamily	0.0127	0.1344	0.1405
Brugia malayi	F/Y-rich N-terminus family protein	0.0018	0.0048	0.0035
Trypanosoma brucei	cysteine peptidase, Clan CA, family C1, Cathepsin L-like	0.0016	0.0029	0.01
Loa Loa (eye worm)	nuclear Hormone Receptor family member	0.0278	0.3134	0.3134
Trypanosoma cruzi	kinesin, putative	0.01	0.102	0.1637

Activities

Activity type	Activity value	Assay description	Source	Reference
EC50 (functional)	= 0.16 uM	Effective agonist concentration to the human Orexin receptor type 2 was determined using the Xlfit program	ChEMBL.	14971895
EC50 (functional)	= 0.16 uM	Effective agonist concentration to the human Orexin receptor type 2 was determined using the Xlfit program	ChEMBL.	14971895
EC50 (functional)	= 1.2 uM	Effective agonist concentration to human orexin receptor type 1 determined using the Xlfit program	ChEMBL.	14971895
EC50 (functional)	= 1.2 uM	Effective agonist concentration to human orexin receptor type 1 determined using the Xlfit program	ChEMBL.	14971895
Ratio (binding)	= 7.5	Ratio of orexin-1 receptor to orexin-2 receptor in human	ChEMBL.	14971895

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?

In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.

In any case, if you have information about papers containing relevant validation data for this target, please log in using your TDR Targets username and password and send them to us using the corresponding form in this page (only visible to registered users) or contact us.

External resources for this compound

ChEMBL: CHEMBL441924

Bibliographic References

1 literature reference was collected for this gene.

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Detailed information for compound 406591