Activity type | Activity value | Assay description | Source | Reference |
---|---|---|---|---|
MIC (functional) | = 0.5 mg l-1 | Minimum inhibitory concentration against vancomycin-sensitive Enterococcus faecalis in the presence of 30% bovine serum(n=3)(range = 0.125 | ChEMBL. | 15993054 |
MIC (functional) | = 1 mg l-1 | Minimum inhibitory concentration against methicillin-resistant Staphylococcus aureus in the presence of 30% bovine serum | ChEMBL. | 15993054 |
MIC (functional) | = 2 mg l-1 | Minimum inhibitory concentration against methicillin-sensitive Staphylococcus aureus in the presence of 30% bovine serum | ChEMBL. | 15993054 |
MIC (functional) | = 2 mg l-1 | Minimum inhibitory concentration against methicillin-sensitive Staphylococcus epidermidis in the presence of 30% bovine serum | ChEMBL. | 15993054 |
MIC (functional) | = 2 mg l-1 | Minimum inhibitory concentration against vancomycin-sensitive Enterococcus faecium in the presence of 30% bovine serum(n=1) (range = 1-8 mg/l) | ChEMBL. | 15993054 |
MIC (functional) | = 8 mg l-1 | Minimum inhibitory concentration against methicillin-resistant Staphylococcus epidermidis in the presence of 30% bovine serum | ChEMBL. | 15993054 |
MIC (functional) | = 8 mg l-1 | Minimum inhibitory concentration against vancomycin-A Enterococcus faecalis in the presence of 30% bovine serum (n=4) (Range = 1 - 8 mg/L) | ChEMBL. | 15993054 |
MIC (functional) | = 32 mg l-1 | Minimum inhibitory concentration against Staphylococcus haemolyticus in the presence of 30% bovine serum | ChEMBL. | 15993054 |
MIC (functional) | > 128 mg l-1 | Minimum inhibitory concentration against vancomycin-A Enterococcus faecium in the presence of 30% bovine serum (n=1) (range = 2 | ChEMBL. | 15993054 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.
1 literature reference was collected for this gene.