Species | Target name | Source | Bibliographic reference |
---|---|---|---|
Homo sapiens | integrin, beta 3 (platelet glycoprotein IIIa, antigen CD61) | Starlite/ChEMBL | References |
Species | Potential target | Known druggable target/s | Ortholog Group |
---|---|---|---|
Schistosoma japonicum | Integrin beta-3 precursor, putative | Get druggable targets OG5_127959 | All targets in OG5_127959 |
Schistosoma mansoni | integrin beta subunit | Get druggable targets OG5_127959 | All targets in OG5_127959 |
Brugia malayi | Integrin beta pat-3 precursor | Get druggable targets OG5_127959 | All targets in OG5_127959 |
Loa Loa (eye worm) | integrin beta-2 | Get druggable targets OG5_127959 | All targets in OG5_127959 |
Schistosoma japonicum | ko:K06464 integrin beta 2, putative | Get druggable targets OG5_127959 | All targets in OG5_127959 |
Schistosoma japonicum | Integrin beta-PS precursor, putative | Get druggable targets OG5_127959 | All targets in OG5_127959 |
Echinococcus granulosus | integrin beta 2 | Get druggable targets OG5_127959 | All targets in OG5_127959 |
Echinococcus multilocularis | integrin beta 2 | Get druggable targets OG5_127959 | All targets in OG5_127959 |
Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Treponema pallidum | adenosine deaminase | 0.0544 | 1 | 0.5 |
Toxoplasma gondii | Adenosine/AMP deaminase domain-containing protein | 0.0544 | 1 | 0.5 |
Schistosoma mansoni | adenosine deaminase-related | 0.0544 | 1 | 1 |
Loa Loa (eye worm) | integrin beta-2 | 0.0378 | 0.4847 | 0.0662 |
Mycobacterium tuberculosis | Probable adenosine deaminase Add (adenosine aminohydrolase) | 0.0544 | 1 | 0.5 |
Echinococcus granulosus | adenosine deaminase | 0.0544 | 1 | 1 |
Entamoeba histolytica | adenosine deaminase, putative | 0.0544 | 1 | 0.5 |
Toxoplasma gondii | Adenosine/AMP deaminase domain-containing protein | 0.0544 | 1 | 0.5 |
Trichomonas vaginalis | adenosine deaminase, putative | 0.0544 | 1 | 0.5 |
Mycobacterium leprae | Probable adenosine deaminase Add (ADENOSINE AMINOHYDROLASE) | 0.0544 | 1 | 0.5 |
Leishmania major | adenine aminohydrolase | 0.0544 | 1 | 0.5 |
Echinococcus multilocularis | adenosine deaminase | 0.0544 | 1 | 1 |
Plasmodium vivax | adenosine deaminase, putative | 0.0544 | 1 | 0.5 |
Loa Loa (eye worm) | hypothetical protein | 0.0544 | 1 | 1 |
Trichomonas vaginalis | adenosine deaminase, putative | 0.0544 | 1 | 0.5 |
Onchocerca volvulus | Adenosine deaminase homolog | 0.0544 | 1 | 0.5 |
Mycobacterium ulcerans | adenosine deaminase | 0.0544 | 1 | 0.5 |
Schistosoma mansoni | adenosine deaminase | 0.0544 | 1 | 1 |
Plasmodium falciparum | adenosine deaminase | 0.0544 | 1 | 0.5 |
Entamoeba histolytica | adenosine deaminase, putative | 0.0544 | 1 | 0.5 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.
1 literature reference was collected for this gene.