Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Echinococcus multilocularis | lysosomal alpha glucosidase | 0.016 | 0.0979 | 0.0979 |
Brugia malayi | jmjC domain containing protein | 0.0038 | 0.0085 | 0.0167 |
Trypanosoma cruzi | puromycin-sensitive aminopeptidase-like protein, putative | 0.0074 | 0.0352 | 0.3331 |
Trichomonas vaginalis | set domain proteins, putative | 0.0713 | 0.5022 | 1 |
Brugia malayi | Voltage-gated potassium channel, HERG (KCNH2)-related. C. elegans unc-103 ortholog | 0.0075 | 0.0357 | 0.0773 |
Loa Loa (eye worm) | hypothetical protein | 0.0065 | 0.0284 | 0.0275 |
Loa Loa (eye worm) | beta-lactamase | 0.0037 | 0.0084 | 0.0074 |
Echinococcus multilocularis | puromycin sensitive aminopeptidase | 0.0074 | 0.0352 | 0.0352 |
Echinococcus granulosus | hexokinase | 0.0168 | 0.1036 | 0.1036 |
Loa Loa (eye worm) | jmjC domain-containing protein | 0.0038 | 0.0085 | 0.0075 |
Loa Loa (eye worm) | hypothetical protein | 0.0038 | 0.0088 | 0.0078 |
Plasmodium vivax | proteasome subunit beta type-1, putative | 0.0063 | 0.027 | 0.2535 |
Echinococcus multilocularis | puromycin sensitive aminopeptidase | 0.0074 | 0.0352 | 0.0352 |
Loa Loa (eye worm) | proteasome subunit beta type 2 | 0.0039 | 0.0095 | 0.0085 |
Plasmodium vivax | proteasome subunit beta type-2, putative | 0.0039 | 0.0095 | 0.0832 |
Loa Loa (eye worm) | hypothetical protein | 0.0038 | 0.0085 | 0.0075 |
Echinococcus multilocularis | hexokinase | 0.0168 | 0.1036 | 0.1036 |
Onchocerca volvulus | Alhambra homolog | 0.0116 | 0.066 | 0.1167 |
Trypanosoma brucei | proteasome subunit beta type-2, putative | 0.0039 | 0.0095 | 0.0832 |
Mycobacterium ulcerans | aminopeptidase N PepN | 0.0074 | 0.0352 | 0.8419 |
Trypanosoma cruzi | metallo-peptidase, Clan MA(E) Family M1 | 0.0074 | 0.0352 | 0.3331 |
Schistosoma mansoni | voltage-gated potassium channel | 0.0082 | 0.0407 | 0.0339 |
Toxoplasma gondii | histone lysine demethylase JMJD6a | 0.0038 | 0.0085 | 0.0728 |
Loa Loa (eye worm) | aminopeptidase N | 0.0074 | 0.0352 | 0.0342 |
Trypanosoma brucei | JmjC domain, hydroxylase, putative | 0.0038 | 0.0085 | 0.0728 |
Brugia malayi | Bromodomain containing protein | 0.0116 | 0.066 | 0.1449 |
Loa Loa (eye worm) | jmjC domain-containing protein | 0.024 | 0.1565 | 0.1556 |
Echinococcus granulosus | lysine specific demethylase 6a | 0.0038 | 0.0085 | 0.0085 |
Trypanosoma cruzi | puromycin-sensitive aminopeptidase-like protein, putative | 0.0074 | 0.0352 | 0.3331 |
Brugia malayi | jmjC domain containing protein | 0.0038 | 0.0085 | 0.0167 |
Mycobacterium tuberculosis | Possible penicillin-binding protein | 0.0239 | 0.1555 | 1 |
Echinococcus granulosus | Jumonji AT rich interactive domain 1B | 0.0038 | 0.0085 | 0.0085 |
Onchocerca volvulus | 0.0092 | 0.0486 | 0.0815 | |
Loa Loa (eye worm) | hypothetical protein | 0.0114 | 0.0647 | 0.0637 |
Echinococcus multilocularis | proteasome (prosome, macropain) | 0.0081 | 0.0402 | 0.0402 |
Brugia malayi | AF-10 protein | 0.0038 | 0.0088 | 0.0174 |
Trichomonas vaginalis | D-aminoacylase, putative | 0.0037 | 0.0084 | 0.0028 |
Onchocerca volvulus | 0.009 | 0.0467 | 0.0777 | |
Schistosoma mansoni | histone-lysine n-methyltransferase setb1 | 0.009 | 0.0467 | 0.04 |
Trichomonas vaginalis | D-aminoacylase, putative | 0.0037 | 0.0084 | 0.0028 |
Echinococcus multilocularis | puromycin sensitive aminopeptidase | 0.0074 | 0.0352 | 0.0352 |
Echinococcus multilocularis | potassium voltage gated channel subfamily H | 0.0075 | 0.0357 | 0.0357 |
Leishmania major | hexokinase, putative | 0.0168 | 0.1036 | 1 |
Brugia malayi | Corticotropin releasing factor receptor 2 precursor, putative | 0.0054 | 0.0205 | 0.0435 |
Echinococcus multilocularis | leukotriene A 4 hydrolase | 0.1394 | 1 | 1 |
Brugia malayi | TATA binding protein associated factor | 0.0074 | 0.0352 | 0.0762 |
Trypanosoma brucei | metallo-peptidase, Clan MA(E) Family M1 | 0.0074 | 0.0352 | 0.3331 |
Echinococcus multilocularis | neutral alpha glucosidase AB | 0.0035 | 0.007 | 0.007 |
Trypanosoma cruzi | metallo-peptidase, clan MA(E), family M1, putative | 0.0074 | 0.0352 | 0.3331 |
Echinococcus granulosus | 5'partial|histone lysine N methyltransferase SETDB2 | 0.0087 | 0.0443 | 0.0443 |
Trypanosoma brucei | PHD-zinc-finger like domain containing protein, putative | 0.0038 | 0.0088 | 0.0762 |
Brugia malayi | jmjC domain containing protein | 0.0141 | 0.0839 | 0.1848 |
Echinococcus multilocularis | peregrin | 0.0116 | 0.066 | 0.066 |
Onchocerca volvulus | 0.0168 | 0.1036 | 0.193 | |
Trypanosoma brucei | PHD-zinc-finger like domain containing protein, putative | 0.0038 | 0.0088 | 0.0762 |
Toxoplasma gondii | histone lysine methyltransferase SET/SUV39 | 0.009 | 0.0467 | 0.4455 |
Echinococcus granulosus | peregrin | 0.0116 | 0.066 | 0.066 |
Loa Loa (eye worm) | beta-LACTamase domain containing family member | 0.0037 | 0.0084 | 0.0074 |
Plasmodium vivax | M1-family alanyl aminopeptidase, putative | 0.0074 | 0.0352 | 0.3331 |
Schistosoma mansoni | hypothetical protein | 0.0116 | 0.066 | 0.0594 |
Loa Loa (eye worm) | hypothetical protein | 0.0037 | 0.0084 | 0.0074 |
Echinococcus granulosus | puromycin sensitive aminopeptidase | 0.0074 | 0.0352 | 0.0352 |
Schistosoma mansoni | family S12 unassigned peptidase (S12 family) | 0.0037 | 0.0084 | 0.0014 |
Echinococcus multilocularis | aminopeptidase N | 0.0074 | 0.0352 | 0.0352 |
Schistosoma mansoni | ubiquitously transcribed sex (X/Y) chromosome tetratricopeptide repeat protein-related | 0.0038 | 0.0085 | 0.0015 |
Trypanosoma cruzi | proteasome subunit beta type-5, putative | 0.0081 | 0.0402 | 0.3821 |
Leishmania major | alpha glucosidase II subunit, putative | 0.0035 | 0.007 | 0.0583 |
Trypanosoma cruzi | hexokinase, putative | 0.0168 | 0.1036 | 1 |
Brugia malayi | Proteasome A-type and B-type family protein | 0.0081 | 0.0402 | 0.0875 |
Trypanosoma cruzi | metallo-peptidase, clan MA(E), family M1, putative | 0.0074 | 0.0352 | 0.3331 |
Brugia malayi | beta-lactamase family protein | 0.0037 | 0.0084 | 0.0164 |
Plasmodium vivax | M1-family alanyl aminopeptidase, putative | 0.0074 | 0.0352 | 0.3331 |
Brugia malayi | Hexokinase family protein | 0.0168 | 0.1036 | 0.2289 |
Loa Loa (eye worm) | peptidase family M1 containing protein | 0.0074 | 0.0352 | 0.0342 |
Toxoplasma gondii | ABC1 family protein | 0.0037 | 0.0084 | 0.0717 |
Loa Loa (eye worm) | hypothetical protein | 0.0037 | 0.0084 | 0.0074 |
Brugia malayi | latrophilin 2 splice variant baaae | 0.0037 | 0.008 | 0.0157 |
Leishmania major | proteasome beta 6 subunit, putative,20S proteasome beta 6 subunit, putative | 0.0063 | 0.027 | 0.2535 |
Trichomonas vaginalis | voltage and ligand gated potassium channel, putative | 0.007 | 0.0321 | 0.0507 |
Brugia malayi | hypothetical protein | 0.0641 | 0.4495 | 1 |
Onchocerca volvulus | 0.0713 | 0.5022 | 1 | |
Echinococcus multilocularis | Jumonji, AT rich interactive domain 1B | 0.0038 | 0.0085 | 0.0085 |
Schistosoma mansoni | hexokinase | 0.0168 | 0.1036 | 0.0974 |
Onchocerca volvulus | 0.0074 | 0.0352 | 0.0543 | |
Trypanosoma brucei | Aminopeptidase M1, putative | 0.0074 | 0.0352 | 0.3331 |
Loa Loa (eye worm) | hypothetical protein | 0.0116 | 0.066 | 0.0651 |
Toxoplasma gondii | proteasome subunit beta type 2, putative | 0.0039 | 0.0095 | 0.0832 |
Echinococcus granulosus | proteasome prosome macropain | 0.0081 | 0.0402 | 0.0402 |
Mycobacterium ulcerans | aminopeptidase N PepN | 0.0074 | 0.0352 | 0.8419 |
Echinococcus granulosus | JmjC domain containing protein 4 | 0.0038 | 0.0085 | 0.0085 |
Trypanosoma brucei | hypothetical protein, conserved | 0.0037 | 0.0084 | 0.0717 |
Trypanosoma brucei | aminopeptidase, putative | 0.0074 | 0.0352 | 0.3331 |
Loa Loa (eye worm) | pre-SET domain-containing protein family protein | 0.0627 | 0.4389 | 0.4384 |
Toxoplasma gondii | PHD-finger domain-containing protein | 0.0116 | 0.066 | 0.6333 |
Plasmodium falciparum | JmjC domain-containing protein, putative | 0.0038 | 0.0085 | 0.0728 |
Brugia malayi | Pre-SET motif family protein | 0.009 | 0.0467 | 0.102 |
Loa Loa (eye worm) | PHD-finger family protein | 0.0116 | 0.066 | 0.0651 |
Loa Loa (eye worm) | hexokinase | 0.0105 | 0.058 | 0.057 |
Echinococcus multilocularis | jumonji domain containing 1A | 0.0038 | 0.0085 | 0.0085 |
Loa Loa (eye worm) | glycosyl hydrolase family 31 protein | 0.0035 | 0.007 | 0.006 |
Echinococcus granulosus | hexokinase | 0.0168 | 0.1036 | 0.1036 |
Plasmodium falciparum | hexokinase | 0.0168 | 0.1036 | 1 |
Echinococcus multilocularis | lysine specific demethylase 6a | 0.0038 | 0.0085 | 0.0085 |
Plasmodium vivax | JmjC domain containing protein | 0.0038 | 0.0085 | 0.0728 |
Trypanosoma cruzi | 20S proteasome subunit | 0.0039 | 0.0095 | 0.0832 |
Echinococcus granulosus | puromycin sensitive aminopeptidase | 0.0074 | 0.0352 | 0.0352 |
Schistosoma mansoni | jumonji domain containing protein | 0.0038 | 0.0085 | 0.0015 |
Schistosoma mansoni | voltage-gated potassium channel | 0.0082 | 0.0407 | 0.0339 |
Schistosoma mansoni | bromodomain-containing nuclear protein 1 brd1 | 0.0116 | 0.066 | 0.0594 |
Echinococcus granulosus | proteasome prosome macropain subunit beta | 0.0063 | 0.027 | 0.027 |
Loa Loa (eye worm) | hypothetical protein | 0.0074 | 0.0352 | 0.0342 |
Trypanosoma cruzi | hexokinase, putative | 0.0168 | 0.1036 | 1 |
Toxoplasma gondii | aminopeptidase n, putative | 0.0074 | 0.0352 | 0.3331 |
Loa Loa (eye worm) | hexokinase | 0.0168 | 0.1036 | 0.1028 |
Schistosoma mansoni | alpha-glucosidase | 0.0138 | 0.0816 | 0.0752 |
Leishmania major | proteasome beta 2 subunit, putative | 0.0039 | 0.0095 | 0.0832 |
Entamoeba histolytica | probable proteasome subunit beta type 2, putative | 0.0039 | 0.0095 | 0.0265 |
Trypanosoma brucei | glucosidase, putative | 0.0035 | 0.007 | 0.0583 |
Onchocerca volvulus | 0.0168 | 0.1036 | 0.193 | |
Echinococcus granulosus | geminin | 0.0166 | 0.102 | 0.102 |
Entamoeba histolytica | proteasome subunit beta type 5 precursor, putative | 0.0081 | 0.0402 | 0.3439 |
Echinococcus granulosus | microtubule associated protein 2 | 0.0747 | 0.5271 | 0.5271 |
Echinococcus multilocularis | PHD finger protein rhinoceros | 0.0116 | 0.066 | 0.066 |
Plasmodium falciparum | proteasome subunit beta type-2, putative | 0.0039 | 0.0095 | 0.0832 |
Trypanosoma brucei | hexokinase | 0.0168 | 0.1036 | 1 |
Plasmodium falciparum | phd finger protein, putative | 0.0116 | 0.066 | 0.6333 |
Schistosoma mansoni | leukotriene A4 hydrolase (M01 family) | 0.1394 | 1 | 1 |
Brugia malayi | Pre-SET motif family protein | 0.0627 | 0.4389 | 0.9764 |
Echinococcus granulosus | Transcription factor JmjC domain containing protein | 0.0381 | 0.2593 | 0.2593 |
Toxoplasma gondii | WD domain, G-beta repeat-containing protein | 0.0038 | 0.0088 | 0.0762 |
Echinococcus multilocularis | Transcription factor, JmjC domain containing protein | 0.0381 | 0.2593 | 0.2593 |
Leishmania major | hypothetical protein, conserved | 0.0037 | 0.0084 | 0.0717 |
Schistosoma mansoni | jumonji domain containing protein | 0.0302 | 0.2021 | 0.1965 |
Schistosoma mansoni | alpha-glucosidase | 0.0138 | 0.0816 | 0.0752 |
Toxoplasma gondii | proteasome subunit beta type, putative | 0.0081 | 0.0402 | 0.3821 |
Toxoplasma gondii | glycosyl hydrolase, family 31 protein | 0.0035 | 0.007 | 0.0583 |
Echinococcus granulosus | hexokinase type 2 | 0.0168 | 0.1036 | 0.1036 |
Schistosoma mansoni | transcription factor LCR-F1 | 0.0039 | 0.0095 | 0.0026 |
Brugia malayi | beta-lactamase family protein | 0.0037 | 0.0084 | 0.0164 |
Loa Loa (eye worm) | hypothetical protein | 0.0037 | 0.008 | 0.007 |
Schistosoma mansoni | jumonji/arid domain-containing protein | 0.0141 | 0.0839 | 0.0774 |
Trypanosoma cruzi | proteasome beta 6 subunit, putative | 0.0063 | 0.027 | 0.2535 |
Brugia malayi | jmjC domain containing protein | 0.0038 | 0.0085 | 0.0167 |
Loa Loa (eye worm) | MH2 domain-containing protein | 0.0124 | 0.0716 | 0.0707 |
Plasmodium vivax | hypothetical protein, conserved | 0.0116 | 0.066 | 0.6333 |
Schistosoma mansoni | proteasome subunit beta 2 (T01 family) | 0.0039 | 0.0095 | 0.0026 |
Leishmania major | hexokinase, putative | 0.0168 | 0.1036 | 1 |
Mycobacterium leprae | proteasome (beta subunit) PrcB | 0.0081 | 0.0402 | 1 |
Trypanosoma brucei | hexokinase, putative | 0.0168 | 0.1036 | 1 |
Trichomonas vaginalis | D-aminoacylase, putative | 0.0037 | 0.0084 | 0.0028 |
Trichomonas vaginalis | penicillin-binding protein, putative | 0.0037 | 0.0084 | 0.0028 |
Brugia malayi | Calcitonin receptor-like protein seb-1 | 0.0054 | 0.0205 | 0.0435 |
Trypanosoma cruzi | hypothetical protein, conserved | 0.0037 | 0.0084 | 0.0717 |
Brugia malayi | jmjC domain containing protein | 0.0381 | 0.2593 | 0.5759 |
Brugia malayi | hexokinase type II | 0.0053 | 0.02 | 0.0424 |
Echinococcus multilocularis | proteasome (prosome, macropain) subunit, beta | 0.0063 | 0.027 | 0.027 |
Trichomonas vaginalis | Family T1, proteasome beta subunit, threonine peptidase | 0.0039 | 0.0095 | 0.0052 |
Onchocerca volvulus | 0.0074 | 0.0352 | 0.0543 | |
Echinococcus granulosus | puromycin sensitive aminopeptidase | 0.0074 | 0.0352 | 0.0352 |
Echinococcus granulosus | hexokinase | 0.0168 | 0.1036 | 0.1036 |
Toxoplasma gondii | PHD-finger domain-containing protein | 0.0116 | 0.066 | 0.6333 |
Schistosoma mansoni | proteasome catalytic subunit 3 (T01 family) | 0.0081 | 0.0402 | 0.0335 |
Brugia malayi | hypothetical protein | 0.0074 | 0.0352 | 0.0762 |
Brugia malayi | Hexokinase family protein | 0.0052 | 0.019 | 0.0401 |
Schistosoma mansoni | Tata binding protein associated factor (M01 family) | 0.0074 | 0.0352 | 0.0284 |
Brugia malayi | Peptidase family M1 containing protein | 0.0074 | 0.0352 | 0.0762 |
Plasmodium falciparum | proteasome subunit beta type-1, putative | 0.0063 | 0.027 | 0.2535 |
Trypanosoma brucei | Aminopeptidase M1, putative | 0.0074 | 0.0352 | 0.3331 |
Loa Loa (eye worm) | jmjC domain-containing protein | 0.0038 | 0.0085 | 0.0075 |
Echinococcus multilocularis | jumonji domain containing protein | 0.0162 | 0.0993 | 0.0993 |
Schistosoma mansoni | hypothetical protein | 0.0037 | 0.008 | 0.001 |
Schistosoma mansoni | family S12 unassigned peptidase (S12 family) | 0.0037 | 0.0084 | 0.0014 |
Schistosoma mansoni | histone-lysine n-methyltransferase setb1 | 0.009 | 0.0467 | 0.04 |
Schistosoma mansoni | phd/f-box containing protein | 0.0038 | 0.0085 | 0.0015 |
Loa Loa (eye worm) | proteasome subunit beta type 1 | 0.0063 | 0.027 | 0.0261 |
Loa Loa (eye worm) | pigment dispersing factor receptor c | 0.0054 | 0.0205 | 0.0195 |
Echinococcus multilocularis | beta LACTamase domain containing family member | 0.0037 | 0.0084 | 0.0084 |
Echinococcus granulosus | beta LACTamase domain containing family member | 0.0037 | 0.0084 | 0.0084 |
Trypanosoma brucei | proteasome subunit beta type-5, putative | 0.0081 | 0.0402 | 0.3821 |
Onchocerca volvulus | Hexokinase homolog | 0.0105 | 0.058 | 0.1004 |
Plasmodium vivax | hypothetical protein, conserved | 0.0037 | 0.0084 | 0.0717 |
Entamoeba histolytica | hexokinase 1 | 0.0168 | 0.1036 | 1 |
Echinococcus granulosus | puromycin sensitive aminopeptidase | 0.0074 | 0.0352 | 0.0352 |
Loa Loa (eye worm) | hexokinase type II | 0.0168 | 0.1036 | 0.1028 |
Echinococcus granulosus | Basic leucine zipper bZIP transcription | 0.0039 | 0.0095 | 0.0095 |
Echinococcus multilocularis | hexokinase | 0.0168 | 0.1036 | 0.1036 |
Trichomonas vaginalis | Clan MA, family M1, aminopeptidase N-like metallopeptidase | 0.0074 | 0.0352 | 0.057 |
Loa Loa (eye worm) | leukotriene A4 hydrolase | 0.1394 | 1 | 1 |
Loa Loa (eye worm) | voltage and ligand gated potassium channel | 0.0075 | 0.0357 | 0.0347 |
Toxoplasma gondii | aminopeptidase N protein | 0.0074 | 0.0352 | 0.3331 |
Echinococcus granulosus | PHD finger protein rhinoceros | 0.0116 | 0.066 | 0.066 |
Leishmania major | aminopeptidase, putative,metallo-peptidase, Clan MA(E), Family M1 | 0.0074 | 0.0352 | 0.3331 |
Brugia malayi | MH2 domain containing protein | 0.0124 | 0.0716 | 0.1574 |
Loa Loa (eye worm) | jmjC domain-containing protein | 0.0141 | 0.0839 | 0.083 |
Schistosoma mansoni | mixed-lineage leukemia protein mll | 0.0041 | 0.0112 | 0.0043 |
Echinococcus multilocularis | histone lysine N methyltransferase SETMAR | 0.009 | 0.0467 | 0.0467 |
Entamoeba histolytica | hypothetical protein | 0.0039 | 0.0095 | 0.0263 |
Trichomonas vaginalis | Family T1, proteasome beta subunit, threonine peptidase | 0.0081 | 0.0402 | 0.0671 |
Trypanosoma cruzi | hypothetical protein, conserved | 0.0035 | 0.007 | 0.0583 |
Leishmania major | puromycin-sensitive aminopeptidase-like protein,metallo-peptidase, Clan MA(E), Family M1 | 0.0074 | 0.0352 | 0.3331 |
Onchocerca volvulus | 0.0074 | 0.0352 | 0.0543 | |
Loa Loa (eye worm) | hypothetical protein | 0.0053 | 0.02 | 0.0191 |
Loa Loa (eye worm) | hypothetical protein | 0.009 | 0.0467 | 0.0458 |
Echinococcus multilocularis | histone lysine methyltransferase setb histone lysine methyltransferase eggless | 0.009 | 0.0467 | 0.0467 |
Echinococcus multilocularis | lysine specific demethylase 5A | 0.0141 | 0.0839 | 0.0839 |
Plasmodium vivax | SET domain protein, putative | 0.009 | 0.0467 | 0.4455 |
Trypanosoma cruzi | proteasome subunit beta type-2, putative | 0.0039 | 0.0095 | 0.0832 |
Plasmodium falciparum | M1-family alanyl aminopeptidase | 0.0074 | 0.0352 | 0.3331 |
Toxoplasma gondii | PHD-finger domain-containing protein | 0.0038 | 0.0088 | 0.0762 |
Entamoeba histolytica | proteasome subunit beta type 1, putative | 0.0063 | 0.027 | 0.2074 |
Schistosoma mansoni | cytosol alanyl aminopeptidase (M01 family) | 0.0074 | 0.0352 | 0.0284 |
Echinococcus granulosus | neutral alpha glucosidase AB | 0.0035 | 0.007 | 0.007 |
Loa Loa (eye worm) | hypothetical protein | 0.0037 | 0.0084 | 0.0074 |
Trypanosoma brucei | hexokinase | 0.0168 | 0.1036 | 1 |
Echinococcus granulosus | histone lysine methyltransferase setb | 0.009 | 0.0467 | 0.0467 |
Loa Loa (eye worm) | hypothetical protein | 0.0037 | 0.0084 | 0.0074 |
Echinococcus granulosus | aminopeptidase N | 0.0074 | 0.0352 | 0.0352 |
Loa Loa (eye worm) | hypothetical protein | 0.0037 | 0.0084 | 0.0074 |
Treponema pallidum | hexokinase (hxk) | 0.0168 | 0.1036 | 0.5 |
Schistosoma mansoni | protein phosphatase 2C | 0.0038 | 0.0085 | 0.0015 |
Brugia malayi | jmjC domain containing protein | 0.0038 | 0.0085 | 0.0167 |
Brugia malayi | F/Y-rich N-terminus family protein | 0.0041 | 0.0112 | 0.0228 |
Echinococcus multilocularis | lysosomal alpha glucosidase | 0.016 | 0.0979 | 0.0979 |
Brugia malayi | Hexokinase family protein | 0.0105 | 0.058 | 0.127 |
Entamoeba histolytica | aminopeptidase, putative | 0.0074 | 0.0352 | 0.2918 |
Trichomonas vaginalis | voltage and ligand gated potassium channel, putative | 0.007 | 0.0321 | 0.0507 |
Loa Loa (eye worm) | hypothetical protein | 0.0074 | 0.0352 | 0.0342 |
Trypanosoma cruzi | proteasome subunit beta type-5, putative | 0.0081 | 0.0402 | 0.3821 |
Brugia malayi | proteasome subunit beta type 1 | 0.0063 | 0.027 | 0.058 |
Echinococcus multilocularis | Basic leucine zipper (bZIP) transcription | 0.0039 | 0.0095 | 0.0095 |
Loa Loa (eye worm) | jmjC domain-containing protein | 0.0038 | 0.0085 | 0.0075 |
Schistosoma mansoni | amine GPCR | 0.034 | 0.2292 | 0.2238 |
Leishmania major | aminopeptidase-like protein,metallo-peptidase, Clan MA(E), Family M1 | 0.0074 | 0.0352 | 0.3331 |
Loa Loa (eye worm) | hexokinase | 0.0168 | 0.1036 | 0.1028 |
Trichomonas vaginalis | Family T1, proteasome beta subunit, threonine peptidase | 0.0063 | 0.027 | 0.0405 |
Schistosoma mansoni | histone-lysine n-methyltransferase setb1 | 0.009 | 0.0467 | 0.04 |
Echinococcus granulosus | proteasome prosome macropain subunit beta | 0.0039 | 0.0095 | 0.0095 |
Echinococcus multilocularis | geminin | 0.0166 | 0.102 | 0.102 |
Echinococcus granulosus | lysosomal alpha glucosidase | 0.016 | 0.0979 | 0.0979 |
Plasmodium vivax | hexokinase, putative | 0.0168 | 0.1036 | 1 |
Trypanosoma cruzi | hypothetical protein, conserved | 0.0037 | 0.0084 | 0.0717 |
Trichomonas vaginalis | esterase, putative | 0.0037 | 0.0084 | 0.0028 |
Trichomonas vaginalis | Clan MA, family M1, aminopeptidase N-like metallopeptidase | 0.0074 | 0.0352 | 0.057 |
Loa Loa (eye worm) | hexokinase | 0.0052 | 0.019 | 0.018 |
Brugia malayi | hypothetical protein | 0.0039 | 0.0095 | 0.019 |
Trichomonas vaginalis | Clan MA, family M1, aminopeptidase N-like metallopeptidase | 0.0074 | 0.0352 | 0.057 |
Entamoeba histolytica | hexokinase 2 | 0.0168 | 0.1036 | 1 |
Entamoeba histolytica | hypothetical protein | 0.0039 | 0.0095 | 0.0263 |
Plasmodium vivax | hypothetical protein, conserved | 0.0038 | 0.0088 | 0.0762 |
Schistosoma mansoni | hypothetical protein | 0.0166 | 0.102 | 0.0957 |
Toxoplasma gondii | aminopeptidase N, putative | 0.0074 | 0.0352 | 0.3331 |
Echinococcus multilocularis | proteasome (prosome, macropain) subunit, beta | 0.0039 | 0.0095 | 0.0095 |
Echinococcus multilocularis | microtubule associated protein 2 | 0.0747 | 0.5271 | 0.5271 |
Schistosoma mansoni | microtubule-associated protein tau | 0.0747 | 0.5271 | 0.5237 |
Giardia lamblia | Proteasome subunit beta type 1 | 0.0063 | 0.027 | 0.3097 |
Leishmania major | proteasome beta 5 subunit, putative | 0.0081 | 0.0402 | 0.3821 |
Loa Loa (eye worm) | proteasome A-type and B-type family protein | 0.0081 | 0.0402 | 0.0393 |
Echinococcus granulosus | jumonji domain containing 1A | 0.0038 | 0.0085 | 0.0085 |
Leishmania major | hypothetical protein, conserved | 0.0038 | 0.0085 | 0.0728 |
Schistosoma mansoni | histone-lysine n-methyltransferase suv9 | 0.009 | 0.0467 | 0.04 |
Brugia malayi | beta-lactamase | 0.0037 | 0.0084 | 0.0164 |
Schistosoma mansoni | jumonji/arid domain-containing protein | 0.0141 | 0.0839 | 0.0774 |
Loa Loa (eye worm) | hypothetical protein | 0.0054 | 0.0205 | 0.0195 |
Plasmodium falciparum | conserved Plasmodium membrane protein, unknown function | 0.0038 | 0.0088 | 0.0762 |
Trichomonas vaginalis | penicillin-binding protein, putative | 0.0037 | 0.0084 | 0.0028 |
Brugia malayi | PHD-finger family protein | 0.0116 | 0.066 | 0.1449 |
Trichomonas vaginalis | Family T1, proteasome beta subunit, threonine peptidase | 0.0039 | 0.0095 | 0.0052 |
Schistosoma mansoni | phosphatidylserine receptor | 0.0038 | 0.0085 | 0.0015 |
Trypanosoma cruzi | aminopeptidase, putative | 0.0074 | 0.0352 | 0.3331 |
Schistosoma mansoni | aminopeptidase PILS (M01 family) | 0.0074 | 0.0352 | 0.0284 |
Trypanosoma brucei | proteasome beta 6 subunit | 0.0063 | 0.027 | 0.2535 |
Mycobacterium ulcerans | proteasome PrcB | 0.0081 | 0.0402 | 1 |
Brugia malayi | PHD-finger family protein | 0.0038 | 0.0088 | 0.0174 |
Giardia lamblia | Proteasome subunit beta type 5 precursor | 0.0081 | 0.0402 | 0.5434 |
Echinococcus multilocularis | JmjC domain containing protein 4 | 0.0038 | 0.0085 | 0.0085 |
Plasmodium falciparum | proteasome subunit beta type-5 | 0.0081 | 0.0402 | 0.3821 |
Echinococcus granulosus | lysine specific demethylase 5A | 0.0141 | 0.0839 | 0.0839 |
Echinococcus multilocularis | puromycin sensitive aminopeptidase | 0.0074 | 0.0352 | 0.0352 |
Trypanosoma cruzi | JmjC domain, hydroxylase, putative | 0.0038 | 0.0085 | 0.0728 |
Loa Loa (eye worm) | hypothetical protein | 0.0074 | 0.0352 | 0.0342 |
Echinococcus multilocularis | phd:f box containing protein | 0.0038 | 0.0085 | 0.0085 |
Echinococcus multilocularis | hexokinase type 2 | 0.0168 | 0.1036 | 0.1036 |
Schistosoma mansoni | proteasome subunit beta 1 (T01 family) | 0.0063 | 0.027 | 0.0202 |
Brugia malayi | Peptidase family M1 containing protein | 0.0074 | 0.0352 | 0.0762 |
Trypanosoma cruzi | proteasome beta 6 subunit, putative | 0.0063 | 0.027 | 0.2535 |
Brugia malayi | Hypothetical 52.5 kDa protein ZK945.1 in chromosome II, putative | 0.0037 | 0.0084 | 0.0164 |
Loa Loa (eye worm) | hypothetical protein | 0.0053 | 0.02 | 0.0191 |
Toxoplasma gondii | proteasome subunit beta type 1, putative | 0.0063 | 0.027 | 0.2535 |
Brugia malayi | hypothetical protein | 0.0074 | 0.0352 | 0.0762 |
Brugia malayi | Glycosyl hydrolases family 31 protein | 0.0035 | 0.007 | 0.0133 |
Trypanosoma cruzi | hypothetical protein, conserved | 0.0035 | 0.007 | 0.0583 |
Schistosoma mansoni | hypothetical protein | 0.0166 | 0.102 | 0.0957 |
Trypanosoma cruzi | aminopeptidase, putative | 0.0074 | 0.0352 | 0.3331 |
Loa Loa (eye worm) | hypothetical protein | 0.0037 | 0.0084 | 0.0074 |
Echinococcus granulosus | jumonji domain containing protein | 0.0162 | 0.0993 | 0.0993 |
Echinococcus granulosus | phd:f box containing protein | 0.0038 | 0.0085 | 0.0085 |
Toxoplasma gondii | histone lysine demethylase JMJC1/KDM5D/JARID1D | 0.0038 | 0.0085 | 0.0728 |
Onchocerca volvulus | 0.0168 | 0.1036 | 0.193 | |
Loa Loa (eye worm) | hypothetical protein | 0.0038 | 0.0085 | 0.0075 |
Trypanosoma cruzi | JmjC domain, hydroxylase, putative | 0.0038 | 0.0085 | 0.0728 |
Brugia malayi | Glycosyl hydrolases family 31 protein | 0.016 | 0.0979 | 0.216 |
Toxoplasma gondii | hexokinase | 0.0168 | 0.1036 | 1 |
Echinococcus granulosus | puromycin sensitive aminopeptidase | 0.0074 | 0.0352 | 0.0352 |
Mycobacterium tuberculosis | Proteasome beta subunit PrcB; assembles with alpha subunit PrcA. | 0.0081 | 0.0402 | 0.2165 |
Plasmodium vivax | proteasome subunit beta type-5, putative | 0.0081 | 0.0402 | 0.3821 |
Schistosoma mansoni | hypothetical protein | 0.0039 | 0.0095 | 0.0026 |
Echinococcus multilocularis | puromycin sensitive aminopeptidase | 0.0074 | 0.0352 | 0.0352 |
Entamoeba histolytica | hypothetical protein | 0.0039 | 0.0095 | 0.0263 |
Brugia malayi | hexokinase | 0.0168 | 0.1036 | 0.2289 |
Brugia malayi | Peptidase family M1 containing protein | 0.0074 | 0.0352 | 0.0762 |
Loa Loa (eye worm) | TATA binding protein associated factor | 0.0074 | 0.0352 | 0.0342 |
Schistosoma mansoni | proteasome subunit beta 2 (T01 family) | 0.0039 | 0.0095 | 0.0026 |
Schistosoma mansoni | aminopeptidase A (M01 family) | 0.0074 | 0.0352 | 0.0284 |
Loa Loa (eye worm) | transcription factor SMAD2 | 0.0124 | 0.0716 | 0.0707 |
Giardia lamblia | PHD finger protein 15 | 0.0116 | 0.066 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0199 | 0.1267 | 0.1258 |
Plasmodium falciparum | M1-family alanyl aminopeptidase, putative | 0.0074 | 0.0352 | 0.3331 |
Loa Loa (eye worm) | glycosyl hydrolase family 31 protein | 0.016 | 0.0979 | 0.097 |
Echinococcus multilocularis | hexokinase | 0.0168 | 0.1036 | 0.1036 |
Leishmania major | aminopeptidase, putative,metallo-peptidase, Clan MA(E), Family M1 | 0.0074 | 0.0352 | 0.3331 |
Trypanosoma cruzi | Aminopeptidase M1, putative | 0.0074 | 0.0352 | 0.3331 |
Brugia malayi | proteasome subunit beta type 2 | 0.0039 | 0.0095 | 0.019 |
Schistosoma mansoni | hypothetical protein | 0.0038 | 0.0088 | 0.0019 |
Entamoeba histolytica | hypothetical protein | 0.0039 | 0.0095 | 0.0263 |
Echinococcus granulosus | puromycin sensitive aminopeptidase | 0.0074 | 0.0352 | 0.0352 |
Onchocerca volvulus | 0.0105 | 0.058 | 0.1004 | |
Echinococcus multilocularis | Peptidase M1, membrane alanine aminopeptidase, N terminal | 0.0074 | 0.0352 | 0.0352 |
Echinococcus granulosus | potassium voltage gated channel subfamily H | 0.0075 | 0.0357 | 0.0357 |
Activity type | Activity value | Assay description | Source | Reference |
---|---|---|---|---|
Ki (binding) | = 61 uM | Inhibition of Hepatitis C virus NS3 serine protease | ChEMBL. | 15501035 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.
1 literature reference was collected for this gene.