Detailed information for compound 407694

Basic information

Technical information
  • Name: Unnamed compound
  • MW: 1177.31 | Formula: C56H80N12O16
  • H donors: 13 H acceptors: 16 LogP: -2.87 Rotable bonds: 41
    Rule of 5 violations (Lipinski): 4
  • SMILES: OC(=O)CC[C@@H](C(=O)N[C@H](C(=O)N[C@H](C(=O)O)Cc1ccccc1)C)NC(=O)[C@@H]1CCCN1C(=O)CNC(=O)[C@H](C(C)C)NC(=O)[C@@H](NC(=O)[C@H]([C@H](O)C)NC(=O)[C@@H]1CCCN1C(=O)[C@H](C(C)C)NC(=O)[C@H](Cc1ccccc1)N)CC(=O)N
  • InChi: 1S/C56H80N12O16/c1-29(2)44(53(80)59-28-42(71)67-23-13-19-39(67)51(78)61-36(21-22-43(72)73)49(76)60-31(5)47(74)63-38(56(83)84)26-34-17-11-8-12-18-34)64-50(77)37(27-41(58)70)62-54(81)46(32(6)69)66-52(79)40-20-14-24-68(40)55(82)45(30(3)4)65-48(75)35(57)25-33-15-9-7-10-16-33/h7-12,15-18,29-32,35-40,44-46,69H,13-14,19-28,57H2,1-6H3,(H2,58,70)(H,59,80)(H,60,76)(H,61,78)(H,62,81)(H,63,74)(H,64,77)(H,65,75)(H,66,79)(H,72,73)(H,83,84)/t31-,32+,35-,36-,37-,38-,39-,40-,44-,45-,46-/m0/s1
  • InChiKey: AVBFNLYOPJPZEI-WZZBYECKSA-N  


Substructure search Similarity search

Network

Hover on a compound node to display the structore

Synonyms

No synonyms found for this compound

Targets

Known targets for this compound

Species Target name Source Bibliographic reference
Homo sapiens calcitonin receptor-like Starlite/ChEMBL References

Predicted pathogen targets for this compound

By orthology
No druggable targets predicted by orthology data
By sequence similarity to non orthologous known druggable targets
Species Potential target Known druggable target Length Alignment span Identity
Loa Loa (eye worm) pigment dispersing factor receptor c calcitonin receptor-like 461 aa 434 aa 28.6 %
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Loa Loa (eye worm) nuclear hormone receptor family member nhr-49 0.0136 0.0333 0.0743
Loa Loa (eye worm) hypothetical protein 0.0059 0.0095 0.0213
Echinococcus granulosus rhodopsin orphan GPCR 0.0059 0.0095 0.0432
Echinococcus multilocularis acetylcholine receptor subunit beta 1 0.0043 0.0045 0.0171
Loa Loa (eye worm) hypothetical protein 0.0063 0.0106 0.0238
Schistosoma mansoni thyroid hormone receptor 0.088 0.2625 1
Loa Loa (eye worm) hypothetical protein 0.0059 0.0095 0.0213
Loa Loa (eye worm) nuclear Hormone Receptor family member 0.0136 0.0333 0.0743
Schistosoma mansoni cercarial elastase (S01 family) 0.0137 0.0335 0.1278
Echinococcus granulosus notch 0.0229 0.0618 0.2802
Echinococcus multilocularis laminin 0.0095 0.0205 0.0782
Echinococcus multilocularis glycoprotein Antigen 5 0.0137 0.0335 0.1278
Brugia malayi nuclear hormone receptor family member odr-7 0.0064 0.011 0.0236
Loa Loa (eye worm) hypothetical protein 0.0059 0.0095 0.0213
Loa Loa (eye worm) hypothetical protein 0.0229 0.0618 0.138
Echinococcus granulosus neuropeptide s receptor 0.0509 0.1483 0.6731
Echinococcus multilocularis rhodopsin orphan GPCR 0.0059 0.0095 0.0362
Toxoplasma gondii kringle domain-containing protein 0.0194 0.051 0.8259
Schistosoma mansoni hypothetical protein 0.0059 0.0095 0.0362
Schistosoma mansoni ancient conserved domain protein 2 (cyclin m2) 0.0059 0.0095 0.0362
Echinococcus multilocularis nicotinic acetylcholine receptor alpha subunit 0.0043 0.0045 0.0171
Schistosoma mansoni Tr4/Tr2 (homologue) 0.0136 0.0333 0.1267
Echinococcus multilocularis G protein coupled 5 hydroxytryptamine receptor 0.0059 0.0095 0.0362
Brugia malayi RNA recognition motif domain containing protein 0.0128 0.0307 0.0657
Brugia malayi nuclear receptor subfamily 1, group D, member 1, putative 0.0064 0.011 0.0236
Echinococcus multilocularis slit 2 protein 0.0229 0.0618 0.2353
Brugia malayi Hypothetical 52.5 kDa protein ZK945.1 in chromosome II, putative 0.0072 0.0134 0.0286
Schistosoma mansoni peptide (FMRFamide/somatostatin)-like receptor 0.0059 0.0095 0.0362
Brugia malayi Transmembrane cell adhesion receptor mua-3 precursor, putative 0.0229 0.0618 0.1321
Loa Loa (eye worm) hypothetical protein 0.0059 0.0095 0.0213
Brugia malayi hypothetical protein 0.0059 0.0095 0.0204
Brugia malayi Neurotransmitter-gated ion-channel ligand binding domain containing protein 0.0043 0.0045 0.0096
Schistosoma mansoni RAR-like nuclear receptor 0.0136 0.0333 0.1267
Echinococcus granulosus hypothetical protein 0.0059 0.0095 0.0432
Brugia malayi Calcium binding EGF domain containing protein 0.0229 0.0618 0.1321
Echinococcus multilocularis neuronal acetylcholine receptor subunit alpha 4 0.0043 0.0045 0.0171
Loa Loa (eye worm) hypothetical protein 0.0229 0.0618 0.138
Brugia malayi nuclear receptor NHR-88 0.0136 0.0333 0.0712
Echinococcus multilocularis neuropeptide receptor 0.0059 0.0095 0.0362
Schistosoma mansoni hypothetical protein 0.0136 0.0332 0.1267
Loa Loa (eye worm) melatonin receptor type 1A 0.0059 0.0095 0.0213
Onchocerca volvulus Putative cubilin 0.0229 0.0618 0.0575
Leishmania major alpha glucosidase II subunit, putative 0.0035 0.002 0.0396
Loa Loa (eye worm) beta-LACTamase domain containing family member 0.0072 0.0134 0.0299
Schistosoma mansoni cercarial elastase (S01 family) 0.0137 0.0335 0.1278
Echinococcus granulosus biogenic amine 5HT receptor 0.0059 0.0095 0.0432
Echinococcus granulosus glycine receptor subunit alpha 1 0.0043 0.0045 0.0203
Loa Loa (eye worm) hypothetical protein 0.0064 0.011 0.0246
Echinococcus granulosus fmrfamide receptor 0.0059 0.0095 0.0432
Brugia malayi steroid hormone receptor 0.0136 0.0333 0.0712
Echinococcus multilocularis somatostatin receptor 0.0059 0.0095 0.0362
Schistosoma mansoni cercarial elastase (S01 family) 0.0137 0.0335 0.1278
Brugia malayi notch-like transmembrane receptor 0.0229 0.0618 0.1321
Echinococcus multilocularis rhodopsin orphan GPCR 0.0059 0.0095 0.0362
Schistosoma mansoni hypothetical protein 0.0043 0.0043 0.0163
Loa Loa (eye worm) hypothetical protein 0.0229 0.0618 0.138
Schistosoma mansoni steroid hormone receptor ad4bp 0.0136 0.0333 0.1267
Echinococcus granulosus Basic leucine zipper bZIP transcription 0.0035 0.0021 0.0094
Loa Loa (eye worm) hypothetical protein 0.0059 0.0095 0.0213
Schistosoma mansoni retinoid-x-receptor (RXR) 0.0136 0.0333 0.1267
Onchocerca volvulus 0.0229 0.0618 0.0575
Brugia malayi EGF-like domain containing protein 0.0229 0.0618 0.1321
Brugia malayi nuclear hormone receptor family member nhr-6 0.0064 0.011 0.0236
Schistosoma mansoni notch 0.0229 0.0618 0.2353
Echinococcus granulosus nAChR subunit 0.0043 0.0045 0.0203
Brugia malayi Latrophilin receptor protein 2 0.0063 0.0106 0.0228
Onchocerca volvulus Nuclear receptor subfamily 6 group A member 1 homolog 0.0064 0.011 0.0066
Loa Loa (eye worm) hypothetical protein 0.0043 0.0045 0.01
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0136 0.0333 0.0712
Echinococcus granulosus beta LACTamase domain containing family member 0.0072 0.0134 0.0607
Echinococcus multilocularis notch 0.0229 0.0618 0.2353
Brugia malayi gonadotropin-releasing hormone receptor 2 0.0059 0.0095 0.0204
Loa Loa (eye worm) hypothetical protein 0.0136 0.0333 0.0743
Trichomonas vaginalis D-aminoacylase, putative 0.0072 0.0134 0.1464
Mycobacterium tuberculosis Probable hydrolase 0.0072 0.0134 0.1005
Brugia malayi Dopamine receptor protein 2 0.0059 0.0095 0.0204
Loa Loa (eye worm) hypothetical protein 0.02 0.0527 0.1178
Brugia malayi neuropeptide F receptor 0.0059 0.0095 0.0204
Brugia malayi Nuclear hormone receptor E75 0.0064 0.011 0.0236
Mycobacterium leprae conserved hypothetical protein 0.0072 0.0134 0.5
Loa Loa (eye worm) hypothetical protein 0.0059 0.0095 0.0213
Loa Loa (eye worm) nuclear hormone receptor family member nhr-31 0.0136 0.0333 0.0743
Echinococcus granulosus growth hormone secretagogue receptor type 1 0.0059 0.0095 0.0432
Echinococcus multilocularis sex peptide receptor 0.0059 0.0095 0.0362
Brugia malayi Neurotransmitter-gated ion-channel ligand binding domain containing protein 0.0043 0.0045 0.0096
Brugia malayi AKH receptor 0.0059 0.0095 0.0204
Echinococcus multilocularis alpha 1A adrenergic receptor 0.0059 0.0095 0.0362
Echinococcus granulosus nuclear receptor subfamily 4 group A 0.0064 0.011 0.05
Schistosoma mansoni hypothetical protein 0.0229 0.0618 0.2353
Echinococcus multilocularis tar DNA binding protein 0.0128 0.0307 0.1169
Brugia malayi EGF-like domain containing protein 0.0229 0.0618 0.1321
Mycobacterium tuberculosis Conserved protein 0.0072 0.0134 0.1005
Brugia malayi ORL1-like opioid receptor 0.0059 0.0095 0.0204
Schistosoma mansoni histamine h1 receptor 0.0059 0.0095 0.0362
Loa Loa (eye worm) hypothetical protein 0.0059 0.0095 0.0213
Onchocerca volvulus 0.0229 0.0618 0.0575
Echinococcus multilocularis Tolloid protein 1 0.0095 0.0205 0.0782
Echinococcus multilocularis FTZ F1 alpha 0.0136 0.0333 0.1267
Loa Loa (eye worm) hypothetical protein 0.0043 0.0045 0.01
Echinococcus multilocularis nuclear receptor subfamily 4 group A 0.0064 0.011 0.042
Loa Loa (eye worm) hypothetical protein 0.0059 0.0095 0.0213
Schistosoma mansoni cercarial elastase (S01 family) 0.0137 0.0335 0.1278
Echinococcus multilocularis neural cadherin 0.0229 0.0618 0.2353
Brugia malayi Trypsin family protein 0.0137 0.0335 0.0718
Mycobacterium ulcerans glutaminase 0.0287 0.0797 1
Schistosoma mansoni hypothetical protein 0.0137 0.0335 0.1278
Brugia malayi G-protein coupled receptor 0.0059 0.0095 0.0204
Onchocerca volvulus 0.0059 0.0095 0.0051
Brugia malayi Cadherin domain containing protein 0.0229 0.0618 0.1321
Trichomonas vaginalis CMGC family protein kinase 0.005 0.0066 0.0592
Onchocerca volvulus 0.0137 0.0335 0.0292
Brugia malayi Serotonin receptor 0.0059 0.0095 0.0204
Loa Loa (eye worm) hypothetical protein 0.0059 0.0095 0.0213
Brugia malayi Neurotransmitter-gated ion-channel ligand binding domain containing protein 0.0043 0.0045 0.0096
Echinococcus multilocularis Mitotic checkpoint protein PRCC, C terminal 0.0743 0.2204 0.8396
Echinococcus multilocularis glycine receptor subunit beta 0.0043 0.0045 0.0171
Trichomonas vaginalis CMGC family protein kinase 0.005 0.0066 0.0592
Echinococcus multilocularis neuropeptide receptor A26 0.0509 0.1483 0.5651
Schistosoma mansoni hypothetical protein 0.0137 0.0335 0.1278
Brugia malayi Cation transporter family protein 0.0043 0.0045 0.0096
Loa Loa (eye worm) hypothetical protein 0.0043 0.0045 0.01
Loa Loa (eye worm) hypothetical protein 0.0137 0.0335 0.075
Schistosoma mansoni notch 0.0229 0.0618 0.2353
Echinococcus multilocularis thyroid hormone receptor alpha 0.088 0.2625 1
Echinococcus multilocularis glycine receptor subunit alpha 1 0.0043 0.0045 0.0171
Brugia malayi Delta serrate ligand family protein 0.0229 0.0618 0.1321
Echinococcus multilocularis protein jagged 2 0.0229 0.0618 0.2353
Loa Loa (eye worm) hypothetical protein 0.0043 0.0045 0.01
Schistosoma mansoni alpha-1 adrenergic receptor 0.0059 0.0095 0.0362
Loa Loa (eye worm) LGC-31 protein 0.0043 0.0045 0.01
Echinococcus multilocularis GPCR, family 2 0.0063 0.0106 0.0406
Toxoplasma gondii histone lysine methyltransferase SET1 0.0053 0.0076 0.1227
Loa Loa (eye worm) hypothetical protein 0.0059 0.0095 0.0213
Schistosoma mansoni subfamily S1A unassigned peptidase (S01 family) 0.0137 0.0335 0.1278
Loa Loa (eye worm) hypothetical protein 0.0059 0.0095 0.0213
Trypanosoma cruzi mitogen activated protein kinase 2, putative 0.005 0.0066 0.1296
Echinococcus multilocularis dro:myosuppressin receptor 0.0059 0.0095 0.0362
Onchocerca volvulus 0.0064 0.011 0.0066
Loa Loa (eye worm) hypothetical protein 0.0136 0.0333 0.0743
Brugia malayi hypothetical protein 0.0059 0.0095 0.0204
Schistosoma mansoni peptide (allatostatin)-like receptor 0.0059 0.0095 0.0362
Loa Loa (eye worm) TK/ROR protein kinase 0.0194 0.051 0.114
Entamoeba histolytica hypothetical protein 0.0035 0.0021 1
Loa Loa (eye worm) hypothetical protein 0.0229 0.0618 0.138
Loa Loa (eye worm) nuclear hormone receptor family member nhr-14 0.0136 0.0333 0.0743
Brugia malayi Calcium binding EGF domain containing protein 0.0229 0.0618 0.1321
Onchocerca volvulus 0.0229 0.0618 0.0575
Brugia malayi Cation transporter family protein 0.0043 0.0045 0.0096
Trypanosoma brucei glucosidase, putative 0.0035 0.002 0.1508
Loa Loa (eye worm) hypothetical protein 0.0059 0.0095 0.0213
Schistosoma mansoni egf-like domain protein 0.0095 0.0205 0.0782
Schistosoma mansoni aminopeptidase PILS (M01 family) 0.0137 0.0335 0.1278
Onchocerca volvulus 0.0064 0.011 0.0066
Brugia malayi nuclear receptor NHR-67 0.0064 0.011 0.0236
Echinococcus granulosus tm gpcr rhodopsin 0.0059 0.0095 0.0432
Loa Loa (eye worm) hypothetical protein 0.0229 0.0618 0.138
Onchocerca volvulus 0.0059 0.0095 0.0051
Loa Loa (eye worm) trypsin family protein 0.0137 0.0335 0.075
Onchocerca volvulus 0.0059 0.0095 0.0051
Loa Loa (eye worm) hypothetical protein 0.0043 0.0045 0.01
Loa Loa (eye worm) hypothetical protein 0.0137 0.0335 0.075
Brugia malayi Nuclear hormone receptor-like 1 0.1479 0.4475 0.9575
Loa Loa (eye worm) hypothetical protein 0.0072 0.0134 0.0299
Loa Loa (eye worm) hypothetical protein 0.0059 0.0095 0.0213
Onchocerca volvulus Steroid hormone receptor family member cnr14 homolog 0.0136 0.0333 0.0289
Echinococcus multilocularis COUP TF:Svp nuclear hormone receptor 0.0136 0.0333 0.1267
Echinococcus multilocularis subfamily S1A unassigned peptidase (S01 family) 0.0137 0.0335 0.1278
Schistosoma mansoni notch 0.0229 0.0618 0.2353
Loa Loa (eye worm) hypothetical protein 0.0064 0.011 0.0246
Brugia malayi nuclear hormone receptor 0.0136 0.0333 0.0712
Brugia malayi putative neuropeptide receptor 0.0059 0.0095 0.0204
Loa Loa (eye worm) hypothetical protein 0.0059 0.0095 0.0213
Brugia malayi G-protein coupled receptor 0.0059 0.0095 0.0204
Loa Loa (eye worm) hypothetical protein 0.0229 0.0618 0.138
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0059 0.0095 0.0362
Loa Loa (eye worm) glutamate-gated chloride channel alpha3A subunit 0.0043 0.0045 0.01
Loa Loa (eye worm) hypothetical protein 0.0137 0.0335 0.075
Onchocerca volvulus 0.0059 0.0095 0.0051
Echinococcus granulosus delta-like protein 1 0.0229 0.0618 0.2802
Brugia malayi EGF-like domain containing protein 0.0229 0.0618 0.1321
Schistosoma mansoni muscarinic acetylcholine (GAR) receptor 0.0059 0.0095 0.0362
Loa Loa (eye worm) unidentified vitellogenin-linked transcript protein 6 0.0059 0.0095 0.0213
Plasmodium vivax cysteine repeat modular protein 1, putative 0.0194 0.051 1
Loa Loa (eye worm) hypothetical protein 0.0059 0.0095 0.0213
Brugia malayi nuclear receptor RXR 0.0064 0.011 0.0236
Schistosoma mansoni hypothetical protein 0.0229 0.0618 0.2353
Brugia malayi hypothetical protein 0.0064 0.011 0.0236
Schistosoma mansoni nAChR subunit 0.0043 0.0045 0.0171
Onchocerca volvulus Neurogenic locus notch protein homolog 0.0229 0.0618 0.0575
Schistosoma mansoni peptide (FMRFamide/neurokinin-3)-like receptor 0.0059 0.0095 0.0362
Onchocerca volvulus 0.0229 0.0618 0.0575
Schistosoma mansoni mixed-lineage leukemia protein mll 0.006 0.0095 0.0364
Brugia malayi Mitochondrial import inner membrane translocase subunit Tim17 family protein 0.0043 0.0043 0.0092
Onchocerca volvulus 0.0059 0.0095 0.0051
Schistosoma mansoni septate junction protein 0.0229 0.0618 0.2353
Echinococcus multilocularis fibrillin 1 0.0095 0.0205 0.0782
Schistosoma mansoni neuropeptide f receptor 76f 0.0059 0.0095 0.0362
Loa Loa (eye worm) hypothetical protein 0.0059 0.0095 0.0213
Echinococcus multilocularis Cys loop ligand gated ion channel subunit 0.0043 0.0045 0.0171
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0136 0.0333 0.0712
Brugia malayi hypothetical protein 0.0038 0.003 0.0064
Toxoplasma gondii ABC1 family protein 0.0072 0.0134 0.2167
Echinococcus multilocularis Peptidase S1 S6, chymotrypsin Hap 0.0137 0.0335 0.1278
Echinococcus granulosus Cys loop ligand gated ion channel subunit 0.0043 0.0045 0.0203
Mycobacterium tuberculosis Probable lipase LipD 0.0072 0.0134 0.1005
Trypanosoma cruzi mitogen activated protein kinase 4, putative 0.005 0.0066 0.1296
Echinococcus granulosus laminin 0.0095 0.0205 0.0931
Echinococcus multilocularis lysosomal alpha glucosidase 0.0159 0.0401 0.1527
Echinococcus granulosus mitogen activated protein kinase 3 0.005 0.0066 0.03
Schistosoma mansoni nuclear receptor 2DBD-gamma 0.0136 0.0333 0.1267
Loa Loa (eye worm) hypothetical protein 0.0095 0.0205 0.0459
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0136 0.0333 0.1267
Brugia malayi Nuclear hormone receptor-like 1 0.1544 0.4674 1
Loa Loa (eye worm) notch protein 0.0229 0.0618 0.138
Echinococcus granulosus hepatocyte nuclear factor 4 alpha 0.0136 0.0333 0.1509
Echinococcus multilocularis pyroglutamylated rfamide peptide receptor 0.0059 0.0095 0.0362
Schistosoma mansoni ecdysone-induced protein 78c (dr-78) 0.0072 0.0134 0.0511
Schistosoma mansoni nuclear hormone receptor 0.0064 0.011 0.042
Echinococcus granulosus rhodopsin orphan GPCR 0.0059 0.0095 0.0432
Mycobacterium tuberculosis Possible conserved lipoprotein LpqK 0.0072 0.0134 0.1005
Schistosoma mansoni coup transcription factor 0.0136 0.0333 0.1267
Loa Loa (eye worm) ACC-1 protein 0.0043 0.0045 0.01
Echinococcus multilocularis rhodopsin orphan GPCR 0.0059 0.0095 0.0362
Brugia malayi conserved hypotetical protein 0.0064 0.011 0.0236
Brugia malayi hypothetical protein 0.0059 0.0095 0.0204
Echinococcus multilocularis Nuclear hormone receptor HR96 0.0064 0.011 0.042
Echinococcus granulosus rhodopsin orphan GPCR 0.0059 0.0095 0.0432
Echinococcus multilocularis rhodopsin orphan GPCR 0.0059 0.0095 0.0362
Echinococcus granulosus expressed protein 0.005 0.0066 0.03
Brugia malayi calcium-independent alpha-latrotoxin receptor 2, putative 0.0063 0.0106 0.0228
Echinococcus multilocularis diuretic hormone 44 receptor GPRdih2 0.0063 0.0106 0.0406
Brugia malayi Nuclear hormone receptor-like 1 0.1479 0.4475 0.9575
Onchocerca volvulus 0.0059 0.0095 0.0051
Echinococcus granulosus Nuclear hormone receptor family member nhr 41 0.0136 0.0333 0.1509
Echinococcus multilocularis neurogenic locus protein delta 0.0229 0.0618 0.2353
Brugia malayi EGF-like domain containing protein 0.0229 0.0618 0.1321
Loa Loa (eye worm) nuclear receptor nhr-7B 0.0064 0.011 0.0246
Echinococcus granulosus slit 2 protein 0.0229 0.0618 0.2802
Schistosoma mansoni nAChR subunit 0.0043 0.0045 0.0171
Loa Loa (eye worm) hypothetical protein 0.0043 0.0045 0.01
Schistosoma mansoni amine GPCR 0.0059 0.0095 0.0362
Echinococcus granulosus thyrotropin releasing hormone receptor 0.0059 0.0095 0.0432
Loa Loa (eye worm) hypothetical protein 0.0043 0.0045 0.01
Schistosoma mansoni hypothetical protein 0.04 0.1146 0.4365
Loa Loa (eye worm) DR-78 0.0064 0.011 0.0246
Echinococcus multilocularis protein jagged 1 0.0229 0.0618 0.2353
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0059 0.0095 0.0362
Mycobacterium tuberculosis Probable lipase LipE 0.0072 0.0134 0.1005
Loa Loa (eye worm) excitatory GABA receptor EXP-1A 0.0043 0.0045 0.01
Echinococcus multilocularis neuropeptides capa receptor 0.0059 0.0095 0.0362
Echinococcus granulosus neutral alpha glucosidase AB 0.0035 0.002 0.0092
Leishmania major mitogen activated protein kinase 4, putative;with=GeneDB:LmxM19.1440 0.005 0.0066 0.1296
Trichomonas vaginalis D-aminoacylase, putative 0.0072 0.0134 0.1464
Loa Loa (eye worm) hypothetical protein 0.0059 0.0095 0.0213
Loa Loa (eye worm) hypothetical protein 0.0043 0.0043 0.0096
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0059 0.0095 0.0362
Echinococcus multilocularis cpg binding protein 0.003 0.0003 0.0012
Onchocerca volvulus Nuclear receptor subfamily 6 group A member 1 homolog 0.0064 0.011 0.0066
Schistosoma mansoni retinoic acid receptor RXR 0.0136 0.0333 0.1267
Echinococcus multilocularis nicotinic acetylcholine receptor beta 1 subunit 0.0043 0.0045 0.0171
Echinococcus granulosus neuronal acetylcholine receptor subunit alpha 4 0.0043 0.0045 0.0203
Echinococcus multilocularis nuclear receptor nhr 48 0.0064 0.011 0.042
Schistosoma mansoni histamine-responsive GPCR (AAF21638) 0.0059 0.0095 0.0362
Loa Loa (eye worm) hypothetical protein 0.0064 0.011 0.0246
Echinococcus granulosus Bcl 2 ous antagonist:killer 0.0057 0.0087 0.0396
Echinococcus multilocularis g protein coupled receptor 0.0059 0.0095 0.0362
Echinococcus granulosus pyroglutamylated rfamide peptide receptor 0.0059 0.0095 0.0432
Brugia malayi acetylcholine receptor alpha subunit precursor, putative 0.0043 0.0045 0.0096
Echinococcus multilocularis mitochondrial import inner membrane translocase subunit TIM23, putative 0.0043 0.0043 0.0163
Brugia malayi Calcium binding EGF domain containing protein 0.0095 0.0205 0.0439
Brugia malayi hypothetical protein 0.0059 0.0095 0.0204
Echinococcus multilocularis neurogenic locus notch protein 0.0229 0.0618 0.2353
Loa Loa (eye worm) hypothetical protein 0.0059 0.0095 0.0213
Schistosoma mansoni glutaminase 0.0287 0.0797 0.3035
Echinococcus multilocularis peptide (allatostatin:somatostatin) 0.0059 0.0095 0.0362
Echinococcus multilocularis glycine receptor subunit alpha 1 0.0043 0.0045 0.0171
Brugia malayi Trypsin family protein 0.0137 0.0335 0.0718
Echinococcus multilocularis glycine receptor subunit alpha 1 0.0043 0.0045 0.0171
Schistosoma mansoni hypothetical protein 0.0229 0.0618 0.2353
Brugia malayi ecdysone receptor 0.0064 0.011 0.0236
Schistosoma mansoni subfamily M12A unassigned peptidase (M12 family) 0.0095 0.0205 0.0782
Echinococcus granulosus neuropeptide Y receptor 0.0059 0.0095 0.0432
Echinococcus granulosus nicotinic acetylcholine receptor beta 1 subunit 0.0043 0.0045 0.0203
Brugia malayi Nuclear hormone receptor E75 0.0064 0.011 0.0236
Schistosoma mansoni Pro-neuregulin-4 membrane-bound isoform (Pro-NRG4) [Contains: Neuregulin-4 (NRG-4)] 0.0229 0.0618 0.2353
Brugia malayi Neurotransmitter-gated ion-channel ligand binding domain containing protein 0.0043 0.0045 0.0096
Schistosoma mansoni nAChR subunit 0.0043 0.0045 0.0171
Schistosoma mansoni nuclear hormone receptor 0.0064 0.011 0.042
Loa Loa (eye worm) hypothetical protein 0.0064 0.011 0.0246
Schistosoma mansoni nAChR subunit 0.0043 0.0045 0.0171
Echinococcus multilocularis neuropeptide Y receptor 0.0059 0.0095 0.0362
Schistosoma mansoni hypothetical protein 0.0743 0.2204 0.8396
Loa Loa (eye worm) hypothetical protein 0.0059 0.0095 0.0213
Brugia malayi Nuclear hormone receptor family member nhr-40 0.0136 0.0333 0.0712
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0059 0.0095 0.0362
Echinococcus multilocularis rhodopsin orphan GPCR 0.0059 0.0095 0.0362
Schistosoma mansoni biogenic amine (5HT) receptor 0.0059 0.0095 0.0362
Schistosoma mansoni serine/threonine protein kinase 0.005 0.0066 0.0252
Loa Loa (eye worm) low-density lipoprotein receptor repeat class B containing protein 0.0095 0.0205 0.0459
Echinococcus multilocularis neutral alpha glucosidase AB 0.0035 0.002 0.0077
Schistosoma mansoni cercarial elastase (S01 family) 0.0137 0.0335 0.1278
Loa Loa (eye worm) TAR-binding protein 0.0128 0.0307 0.0686
Plasmodium vivax mitochondrial import inner membrane translocase subunit TIM10, putative 0.005 0.0066 0.1297
Echinococcus granulosus peptide allatostatin:somatostatin 0.0059 0.0095 0.0432
Brugia malayi Calcitonin receptor-like protein seb-1 0.02 0.0527 0.1128
Schistosoma mansoni biogenic amine (5HT) receptor 0.0059 0.0095 0.0362
Loa Loa (eye worm) hypothetical protein 0.0229 0.0618 0.138
Loa Loa (eye worm) hypothetical protein 0.0136 0.0333 0.0743
Brugia malayi Dopamine receptor 0.0059 0.0095 0.0204
Loa Loa (eye worm) hypothetical protein 0.0136 0.0333 0.0743
Loa Loa (eye worm) hypothetical protein 0.0229 0.0618 0.138
Schistosoma mansoni hypothetical protein 0.0057 0.0087 0.0333
Loa Loa (eye worm) RNA binding protein 0.0128 0.0307 0.0686
Brugia malayi hypothetical protein 0.0059 0.0095 0.0204
Schistosoma mansoni hypothetical protein 0.0063 0.0106 0.0406
Trypanosoma cruzi mitogen-activated protein kinase 11, putative 0.005 0.0066 0.1296
Loa Loa (eye worm) hypothetical protein 0.0229 0.0618 0.138
Plasmodium falciparum cysteine repeat modular protein 1 0.0194 0.051 1
Echinococcus multilocularis G protein coupled receptor 139 0.0059 0.0095 0.0362
Echinococcus multilocularis tachykinin peptides receptor 99D 0.0059 0.0095 0.0362
Brugia malayi EGF-like domain containing protein 0.0229 0.0618 0.1321
Brugia malayi Fibulin-1 precursor 0.0095 0.0205 0.0439
Loa Loa (eye worm) hypothetical protein 0.0059 0.0095 0.0213
Echinococcus granulosus nicotinic acetylcholine receptor a11 subunit 0.0043 0.0045 0.0203
Brugia malayi EGF-like domain containing protein 0.0229 0.0618 0.1321
Loa Loa (eye worm) hypothetical protein 0.0059 0.0095 0.0213
Loa Loa (eye worm) hypothetical protein 0.0137 0.0335 0.075
Echinococcus multilocularis Basic leucine zipper (bZIP) transcription 0.0035 0.0021 0.0079
Schistosoma mansoni retinoid-x-receptor (RXR) 0.0072 0.0134 0.0511
Echinococcus granulosus retinoic acid receptor rxr beta a 0.0136 0.0333 0.1509
Schistosoma mansoni neuropeptide receptor 0.0059 0.0095 0.0362
Schistosoma mansoni Cys-loop ligand gated ion channel subunit 0.0043 0.0045 0.0171
Toxoplasma gondii CMGC kinase, MAPK family (ERK) MAPK-1 0.005 0.0066 0.1071
Loa Loa (eye worm) beta-lactamase 0.0072 0.0134 0.0299
Loa Loa (eye worm) hypothetical protein 0.0059 0.0095 0.0213
Echinococcus multilocularis mitogen activated protein kinase 0.005 0.0066 0.0252
Loa Loa (eye worm) multiple epidermal growth factor-like domains 6 0.0095 0.0205 0.0459
Brugia malayi RE15519p 0.0059 0.0095 0.0204
Brugia malayi Glycosyl hydrolases family 31 protein 0.0035 0.002 0.0043
Schistosoma mansoni photoreceptor-specific nuclear receptor related 0.0136 0.0333 0.1267
Loa Loa (eye worm) hypothetical protein 0.0229 0.0618 0.138
Brugia malayi orphan nuclear receptor NR2E1 0.0064 0.011 0.0236
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0059 0.0095 0.0362
Brugia malayi Nuclear hormone receptor family member nhr-14 0.0136 0.0333 0.0712
Schistosoma mansoni hypothetical protein 0.0057 0.0087 0.0333
Echinococcus granulosus somatostatin receptor 0.0059 0.0095 0.0432
Brugia malayi Steroid receptor seven-up type 2 0.0136 0.0333 0.0712
Loa Loa (eye worm) hypothetical protein 0.0072 0.0134 0.0299
Brugia malayi hypothetical protein 0.0059 0.0095 0.0204
Echinococcus granulosus neuropeptides capa receptor 0.0059 0.0095 0.0432
Echinococcus granulosus neuropeptide receptor A26 0.0509 0.1483 0.6731
Brugia malayi G-protein-linked acetylcholine receptor protein 2, putative 0.0059 0.0095 0.0204
Echinococcus multilocularis dnaJ subfamily B 0.04 0.1146 0.4365
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0136 0.0333 0.0712
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0072 0.0134 0.051
Brugia malayi hypothetical protein 0.0035 0.0021 0.0044
Loa Loa (eye worm) G-protein coupled receptor 0.0059 0.0095 0.0213
Leishmania major mitogen activated protein kinase, putative,map kinase, putative 0.005 0.0066 0.1296
Brugia malayi hypothetical protein 0.0059 0.0095 0.0204
Onchocerca volvulus 0.0137 0.0335 0.0292
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0059 0.0095 0.0362
Echinococcus granulosus neuropeptide receptor 0.0059 0.0095 0.0432
Schistosoma mansoni nuclear receptor nhr-48 0.0064 0.011 0.042
Brugia malayi GCC2 and GCC3 family protein 0.0229 0.0618 0.1321
Brugia malayi Serotonin receptor 0.0059 0.0095 0.0204
Loa Loa (eye worm) hypothetical protein 0.0137 0.0335 0.075
Toxoplasma gondii TIM10 family protein, putative 0.005 0.0066 0.1072
Mycobacterium tuberculosis Possible penicillin-binding protein 0.046 0.1331 1
Schistosoma mansoni neuropeptide receptor 0.0059 0.0095 0.0362
Loa Loa (eye worm) hypothetical protein 0.0043 0.0045 0.01
Echinococcus multilocularis serotonin receptor 0.0059 0.0095 0.0362
Echinococcus granulosus GPCR family 2 0.0063 0.0106 0.0483
Echinococcus granulosus g protein linked acetylcholine receptor gar 2a 0.0059 0.0095 0.0432
Loa Loa (eye worm) hypothetical protein 0.0229 0.0618 0.138
Echinococcus granulosus serotonin receptor 0.0059 0.0095 0.0432
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0136 0.0333 0.1267
Onchocerca volvulus 0.0137 0.0335 0.0292
Echinococcus granulosus protein jagged 2 0.0229 0.0618 0.2802
Loa Loa (eye worm) hypothetical protein 0.0072 0.0134 0.0299
Loa Loa (eye worm) hypothetical protein 0.0229 0.0618 0.138
Loa Loa (eye worm) G-protein-linked acetylcholine receptor protein 2 0.0059 0.0095 0.0213
Schistosoma mansoni hypothetical protein 0.0229 0.0618 0.2353
Loa Loa (eye worm) hypothetical protein 0.0059 0.0095 0.0213
Onchocerca volvulus Arrow homolog 0.0095 0.0205 0.0161
Onchocerca volvulus 0.0059 0.0095 0.0051
Mycobacterium leprae Probable lipase LipE 0.0072 0.0134 0.5
Schistosoma mansoni bcl-2 homologous antagonist/killer (bak) 0.0057 0.0087 0.0333
Loa Loa (eye worm) hypothetical protein 0.0059 0.0095 0.0213
Brugia malayi Trypsin family protein 0.0137 0.0335 0.0718
Schistosoma mansoni alpha-glucosidase 0.0137 0.0333 0.1268
Schistosoma mansoni nAChR subunit 0.0043 0.0045 0.0171
Echinococcus multilocularis fat cadherin tumor suppressor 0.0229 0.0618 0.2353
Brugia malayi Nuclear hormone receptor family member nhr-41 0.0136 0.0333 0.0712
Loa Loa (eye worm) hypothetical protein 0.0064 0.011 0.0246
Echinococcus multilocularis g-protein coupled receptor 0.0059 0.0095 0.0362
Brugia malayi acetylcholine receptor protein, alpha-like chain, putative 0.0043 0.0045 0.0096
Echinococcus granulosus glycine receptor subunit beta 0.0043 0.0045 0.0203
Echinococcus granulosus alpha 1A adrenergic receptor 0.0059 0.0095 0.0432
Brugia malayi sulfakinin receptor protein 0.0059 0.0095 0.0204
Brugia malayi ecdysteroid receptor 0.0136 0.0333 0.0712
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0059 0.0095 0.0362
Schistosoma mansoni laminin gamma-3 chain 0.0229 0.0618 0.2353
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0059 0.0095 0.0362
Echinococcus multilocularis FTZ F1 nuclear receptor protein 0.0136 0.0333 0.1267
Echinococcus multilocularis enteropeptidase 0.0137 0.0335 0.1278
Loa Loa (eye worm) hypothetical protein 0.0229 0.0618 0.138
Echinococcus multilocularis nAChR subunit 0.0043 0.0045 0.0171
Brugia malayi nuclear receptor RXR 0.0072 0.0134 0.0287
Brugia malayi Mitochondrial import inner membrane translocase subunit Tim17 family protein 0.0043 0.0043 0.0092
Schistosoma mansoni opsin-like receptor 0.0059 0.0095 0.0362
Loa Loa (eye worm) hypothetical protein 0.0059 0.0095 0.0213
Onchocerca volvulus Neuropeptide F receptor homolog 0.0059 0.0095 0.0051
Loa Loa (eye worm) apoptosis regulator protein 0.0057 0.0087 0.0195
Schistosoma mansoni opsin-like receptor 0.0059 0.0095 0.0362
Loa Loa (eye worm) hypothetical protein 0.0229 0.0618 0.138
Loa Loa (eye worm) hypothetical protein 0.0072 0.0134 0.03
Brugia malayi hypothetical protein 0.0064 0.011 0.0236
Loa Loa (eye worm) hypothetical protein 0.0043 0.0045 0.01
Onchocerca volvulus 0.0092 0.0195 0.015
Echinococcus multilocularis fmrfamide receptor 0.0059 0.0095 0.0362
Trypanosoma cruzi hypothetical protein, conserved 0.0072 0.0134 0.2624
Mycobacterium tuberculosis Probable conserved lipoprotein 0.0072 0.0134 0.1005
Echinococcus granulosus neural cadherin 0.0229 0.0618 0.2802
Loa Loa (eye worm) neuropeptide F receptor 0.0059 0.0095 0.0213
Onchocerca volvulus 0.0059 0.0095 0.0051
Onchocerca volvulus 0.0059 0.0095 0.0051
Schistosoma mansoni cell polarity protein 0.0229 0.0618 0.2353
Brugia malayi Tachykinin-like peptides receptor 99D 0.0059 0.0095 0.0204
Brugia malayi neuropeptide F receptor 0.0059 0.0095 0.0204
Schistosoma mansoni cpg binding protein 0.003 0.0003 0.0012
Loa Loa (eye worm) glutaminase 0.0287 0.0797 0.178
Echinococcus multilocularis G-protein coupled receptor, putative 0.0059 0.0095 0.0362
Loa Loa (eye worm) hypothetical protein 0.0064 0.011 0.0246
Brugia malayi hypothetical protein 0.0072 0.0134 0.0287
Schistosoma mansoni cercarial elastase (S01 family) 0.0137 0.0335 0.1278
Brugia malayi nuclear hormone receptor 0.0064 0.011 0.0236
Brugia malayi nicotinic acetylcholine receptor alpha subunit, putative 0.0043 0.0045 0.0096
Loa Loa (eye worm) hypothetical protein 0.0136 0.0333 0.0743
Echinococcus granulosus 7TM GPCR rhodopsin 0.0059 0.0095 0.0432
Schistosoma mansoni cercarial elastase (S01 family) 0.0137 0.0335 0.1278
Echinococcus multilocularis nicotinic acetylcholine receptor subunit alpha 8 0.0043 0.0045 0.0171
Echinococcus granulosus G protein coupled 5 hydroxytryptamine receptor 0.0059 0.0095 0.0432
Brugia malayi Hypothetical glycine receptor like protein T20B12.9 in chromosome III 0.0043 0.0045 0.0096
Schistosoma mansoni biogenic amine receptor 0.0059 0.0095 0.0362
Schistosoma mansoni neuropeptide F-like receptor 0.0059 0.0095 0.0362
Echinococcus granulosus neuropeptide Y receptor 0.0059 0.0095 0.0432
Onchocerca volvulus 0.0137 0.0335 0.0292
Schistosoma mansoni nuclear receptor 0.0064 0.011 0.042
Loa Loa (eye worm) hypothetical protein 0.0059 0.0095 0.0213
Loa Loa (eye worm) hypothetical protein 0.0059 0.0095 0.0213
Echinococcus granulosus Peptidase S1 S6 chymotrypsin Hap 0.0137 0.0335 0.1522
Loa Loa (eye worm) hypothetical protein 0.0059 0.0095 0.0213
Echinococcus multilocularis biogenic amine (5HT) receptor 0.0059 0.0095 0.0362
Loa Loa (eye worm) hypothetical protein 0.0072 0.0134 0.03
Echinococcus granulosus tar DNA binding protein 0.0128 0.0307 0.1393
Echinococcus granulosus rhodopsin orphan GPCR 0.0059 0.0095 0.0432
Schistosoma mansoni notch 0.0229 0.0618 0.2353
Echinococcus granulosus g-protein coupled receptor 0.0059 0.0095 0.0432
Echinococcus multilocularis nuclear receptor subfamily 1 group D 0.0072 0.0134 0.0511
Echinococcus granulosus mitogen activated protein kinase 0.005 0.0066 0.03
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0059 0.0095 0.0362
Onchocerca volvulus 0.0072 0.0134 0.0089
Schistosoma mansoni apoptosis regulator bax 0.0057 0.0087 0.0333
Schistosoma mansoni hypothetical protein 0.0057 0.0087 0.0333
Brugia malayi Nuclear hormone receptor family member nhr-1 0.0136 0.0333 0.0712
Trypanosoma cruzi mitogen-activated protein kinase 11, putative 0.005 0.0066 0.1296
Loa Loa (eye worm) hypothetical protein 0.0064 0.011 0.0246
Loa Loa (eye worm) follicle stimulating hormone receptor 0.0059 0.0095 0.0213
Schistosoma mansoni notch 0.0229 0.0618 0.2353
Schistosoma mansoni zinc finger protein 0.0064 0.011 0.042
Brugia malayi G protein-coupled receptor F59B2.13 0.0059 0.0095 0.0204
Echinococcus granulosus Mitotic checkpoint protein PRCC C terminal 0.0743 0.2204 1
Brugia malayi Unidentified vitellogenin-linked transcript protein 6, putative 0.0059 0.0095 0.0204
Echinococcus granulosus g protein coupled receptor 0.0059 0.0095 0.0432
Loa Loa (eye worm) hypothetical protein 0.0057 0.0087 0.0195
Echinococcus granulosus rhodopsin orphan GPCR 0.0059 0.0095 0.0432
Loa Loa (eye worm) nuclear hormone receptor-like 1 0.1479 0.4475 1
Echinococcus granulosus Nuclear hormone receptor HR96 0.0064 0.011 0.05
Loa Loa (eye worm) neuropeptide F receptor 0.0059 0.0095 0.0213
Echinococcus granulosus neurogenic locus notch protein 4 0.0229 0.0618 0.2802
Brugia malayi Neurotransmitter-gated ion-channel transmembrane region family protein 0.0043 0.0045 0.0096
Brugia malayi tailless protein 0.0064 0.011 0.0236
Brugia malayi TAR-binding protein 0.0128 0.0307 0.0657
Trypanosoma brucei mitogen activated protein kinase 4, putative 0.005 0.0066 0.4939
Echinococcus granulosus neurogenic locus notch protein 0.0229 0.0618 0.2802
Echinococcus multilocularis neuropeptide FF receptor 2 0.0059 0.0095 0.0362
Brugia malayi follicle stimulating hormone receptor 0.0059 0.0095 0.0204
Schistosoma mansoni hypothetical protein 0.0059 0.0095 0.0362
Schistosoma mansoni biogenic amine (octopamine/dopamine) receptor 0.0059 0.0095 0.0362
Echinococcus multilocularis g protein linked acetylcholine receptor gar 2a 0.0059 0.0095 0.0362
Loa Loa (eye worm) hypothetical protein 0.0137 0.0335 0.075
Schistosoma mansoni cercarial elastase (S01 family) 0.0137 0.0335 0.1278
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0059 0.0095 0.0362
Loa Loa (eye worm) hypothetical protein 0.0059 0.0095 0.0213
Schistosoma mansoni mitochondrial import inner membrane translocase subunit tim10 0.005 0.0066 0.0252
Schistosoma mansoni nuclear hormone receptor superfamily protein-related 0.0064 0.011 0.042
Echinococcus granulosus subfamily S1A unassigned peptidase S01 family 0.0137 0.0335 0.1522
Echinococcus granulosus G protein coupled receptor 139 0.0059 0.0095 0.0432
Schistosoma mansoni thyrotropin-releasing hormone receptor 0.0059 0.0095 0.0362
Onchocerca volvulus 0.0059 0.0095 0.0051
Loa Loa (eye worm) hypothetical protein 0.0043 0.0045 0.01
Loa Loa (eye worm) nuclear hormone receptor family member nhr-40 0.0136 0.0333 0.0743
Loa Loa (eye worm) hypothetical protein 0.0137 0.0335 0.075
Echinococcus multilocularis mitogen activated protein kinase 3 0.005 0.0066 0.0252
Loa Loa (eye worm) hypothetical protein 0.0059 0.0095 0.0213
Loa Loa (eye worm) hypothetical protein 0.0059 0.0095 0.0213
Loa Loa (eye worm) hypothetical protein 0.0229 0.0618 0.138
Echinococcus multilocularis ecdysone induced protein 78C 0.0136 0.0333 0.1267
Echinococcus multilocularis lysosomal alpha glucosidase 0.0159 0.0401 0.1527
Echinococcus granulosus nuclear receptor nhr 48 0.0064 0.011 0.05
Echinococcus granulosus neurogenic locus notch protein 0.0229 0.0618 0.2802
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0064 0.011 0.042
Loa Loa (eye worm) hypothetical protein 0.0229 0.0618 0.138
Echinococcus multilocularis allatostatin A receptor 0.0059 0.0095 0.0362
Brugia malayi Melatonin receptor type 1A 0.0059 0.0095 0.0204
Loa Loa (eye worm) hypothetical protein 0.0072 0.0134 0.0299
Loa Loa (eye worm) ligand-Gated ion Channel family member 0.0043 0.0045 0.01
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0136 0.0333 0.0712
Trypanosoma cruzi hypothetical protein, conserved 0.0035 0.002 0.0396
Echinococcus granulosus cadherin EGF LAG seven pass G type receptor 0.0063 0.0106 0.0483
Onchocerca volvulus 0.0059 0.0095 0.0051
Loa Loa (eye worm) latrophilin receptor protein 2 0.0063 0.0106 0.0238
Plasmodium vivax mitochondrial import inner membrane translocase subunit TIM23, putative 0.0043 0.0043 0.084
Brugia malayi Nuclear hormone receptor family member nhr-49 0.0136 0.0333 0.0712
Loa Loa (eye worm) hypothetical protein 0.0064 0.011 0.0246
Brugia malayi Mitochondrial import inner membrane translocase subunit TIM10 0.005 0.0066 0.0142
Brugia malayi Trypsin-like protease protein 5 0.0137 0.0335 0.0718
Brugia malayi larval opioid receptor 0.0059 0.0095 0.0204
Schistosoma mansoni amine GPCR 0.0059 0.0095 0.0362
Echinococcus granulosus protein jagged 2 0.0229 0.0618 0.2802
Echinococcus granulosus nuclear receptor subfamily 1 group D 0.0072 0.0134 0.0608
Echinococcus granulosus neuropeptides capa receptor 0.0059 0.0095 0.0432
Onchocerca volvulus 0.0072 0.0134 0.0089
Echinococcus multilocularis retinoic acid receptor rxr beta a retinoic acid receptor rxr alpha a retinoic acid receptor rxr alpha 0.0064 0.011 0.042
Brugia malayi Glycosyl hydrolases family 31 protein 0.0159 0.0401 0.0858
Loa Loa (eye worm) nuclear hormone receptor family member nhr-1 0.0136 0.0333 0.0743
Echinococcus multilocularis nicotinic acetylcholine receptor a11 subunit 0.0043 0.0045 0.0171
Onchocerca volvulus 0.0137 0.0335 0.0292
Echinococcus granulosus glycine receptor subunit beta 0.0043 0.0045 0.0203
Echinococcus multilocularis neurogenic locus protein delta 0.0229 0.0618 0.2353
Onchocerca volvulus Slit protein homolog 0.0229 0.0618 0.0575
Mycobacterium tuberculosis Conserved protein 0.0072 0.0134 0.1005
Plasmodium falciparum mitochondrial import inner membrane translocase subunit TIM23, putative 0.0043 0.0043 0.084
Echinococcus multilocularis neuropeptides capa receptor 0.0059 0.0095 0.0362
Echinococcus granulosus orexin receptor type 2 0.0059 0.0095 0.0432
Schistosoma mansoni tar DNA-binding protein 0.0128 0.0307 0.1169
Schistosoma mansoni hypothetical protein 0.0063 0.0106 0.0406
Onchocerca volvulus 0.0136 0.0333 0.0289
Schistosoma mansoni subfamily S1A unassigned peptidase (S01 family) 0.0137 0.0335 0.1278
Brugia malayi Neurotransmitter-gated ion-channel ligand binding domain containing protein 0.0043 0.0045 0.0096
Loa Loa (eye worm) hypothetical protein 0.0043 0.0045 0.01
Loa Loa (eye worm) pigment dispersing factor receptor c 0.02 0.0527 0.1178
Echinococcus granulosus neurogenic locus protein delta 0.0229 0.0618 0.2802
Loa Loa (eye worm) hypothetical protein 0.0229 0.0618 0.138
Loa Loa (eye worm) hypothetical protein 0.0136 0.0333 0.0743
Loa Loa (eye worm) hypothetical protein 0.0229 0.0618 0.138
Brugia malayi Muscle positioning protein 4 0.0229 0.0618 0.1321
Mycobacterium tuberculosis Probable esterase LipL 0.0072 0.0134 0.1005
Trypanosoma cruzi hypothetical protein, conserved 0.0072 0.0134 0.2624
Schistosoma mansoni tar DNA-binding protein 0.0128 0.0307 0.1169
Brugia malayi RNA binding protein 0.0128 0.0307 0.0657
Loa Loa (eye worm) hypothetical protein 0.0043 0.0045 0.01
Echinococcus granulosus Tolloid protein 1 0.0095 0.0205 0.0931
Echinococcus granulosus fibropellin Ia 0.0229 0.0618 0.2802
Loa Loa (eye worm) hypothetical protein 0.0072 0.0134 0.0299
Schistosoma mansoni amine GPCR 0.0059 0.0095 0.0362
Echinococcus multilocularis neurogenic locus notch protein 4 0.0229 0.0618 0.2353
Schistosoma mansoni growth hormone secretagogue receptor 0.0059 0.0095 0.0362
Brugia malayi Kringle domain containing protein 0.0194 0.051 0.1091
Schistosoma mansoni subfamily S1A unassigned peptidase (S01 family) 0.0137 0.0335 0.1278
Mycobacterium ulcerans hypothetical protein 0.0137 0.0335 0.3043
Echinococcus multilocularis transmembrane protease serine 3 0.0137 0.0335 0.1278
Loa Loa (eye worm) hypothetical protein 0.0059 0.0095 0.0213
Schistosoma mansoni peptide (allatostatin/somatostatin)-like receptor 0.0059 0.0095 0.0362
Echinococcus multilocularis orexin receptor type 2 0.0059 0.0095 0.0362
Loa Loa (eye worm) hypothetical protein 0.0064 0.011 0.0246
Trichomonas vaginalis CMGC family protein kinase 0.005 0.0066 0.0592
Echinococcus granulosus transmembrane protease serine 3 0.0137 0.0335 0.1522
Echinococcus granulosus protein jagged 1 0.0229 0.0618 0.2802
Brugia malayi Protein kinase domain containing protein 0.0194 0.051 0.1091
Trypanosoma brucei hypothetical protein, conserved 0.0072 0.0134 1
Echinococcus multilocularis thyrotropin releasing hormone receptor 0.0059 0.0095 0.0362
Echinococcus multilocularis rhodopsin orphan GPCR 0.0059 0.0095 0.0362
Echinococcus multilocularis Mastin 0.0137 0.0335 0.1278
Toxoplasma gondii mitochondrial inner membrane translocase subunit TIM17, putative 0.0043 0.0043 0.0694
Loa Loa (eye worm) transport to inner mitochondrial membrane family member 0.005 0.0066 0.0148
Loa Loa (eye worm) nicotinic acetylcholine receptor alpha subunit 0.0043 0.0045 0.01
Echinococcus granulosus COUP TF:Svp nuclear hormone receptor 0.0136 0.0333 0.1509
Echinococcus multilocularis neuropeptide Y receptor 0.0059 0.0095 0.0362
Schistosoma mansoni nAChR subunit 0.0043 0.0045 0.0171
Loa Loa (eye worm) hypothetical protein 0.0059 0.0095 0.0213
Loa Loa (eye worm) hypothetical protein 0.0095 0.0205 0.0459
Loa Loa (eye worm) hypothetical protein 0.0059 0.0095 0.0213
Echinococcus granulosus enteropeptidase 0.0137 0.0335 0.1522
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0059 0.0095 0.0362
Echinococcus multilocularis Bcl 2 ous antagonist:killer 0.0057 0.0087 0.0333
Entamoeba histolytica hypothetical protein 0.0035 0.0021 1
Loa Loa (eye worm) TYRA-2 protein 0.0059 0.0095 0.0213
Brugia malayi Calcium binding EGF domain containing protein 0.0229 0.0618 0.1321
Loa Loa (eye worm) hypothetical protein 0.0095 0.0205 0.0459
Schistosoma mansoni neuropeptide receptor 0.0059 0.0095 0.0362
Loa Loa (eye worm) hypothetical protein 0.0043 0.0045 0.01
Loa Loa (eye worm) hypothetical protein 0.0059 0.0095 0.0213
Echinococcus granulosus EGFP:Bcl2 fusion protein 0.0057 0.0087 0.0396
Echinococcus multilocularis expressed protein 0.005 0.0066 0.0252
Brugia malayi hypothetical protein 0.0059 0.0095 0.0204
Schistosoma mansoni peptide (FMRFamide/somatostatin)-like receptor 0.0059 0.0095 0.0362
Loa Loa (eye worm) hypothetical protein 0.0194 0.051 0.114
Echinococcus granulosus g protein linked acetylcholine receptor gar 2a 0.0059 0.0095 0.0432
Brugia malayi Dopamine receptor protein 1, putative (partial) 0.0059 0.0095 0.0204
Schistosoma mansoni nuclear receptor 0.0064 0.011 0.042
Brugia malayi nuclear receptor NHR-88 0.0064 0.011 0.0236
Onchocerca volvulus 0.0059 0.0095 0.0051
Brugia malayi glutaminase DH11.1 0.0287 0.0797 0.1704
Brugia malayi Chymotrypsin-like protease CTRL-1 precursor 0.0137 0.0335 0.0718
Schistosoma mansoni hypothetical protein 0.0059 0.0095 0.0362
Brugia malayi Serotonin/octopamine receptor family protein 7 0.0059 0.0095 0.0204
Loa Loa (eye worm) CMGC/MAPK/ERK1 protein kinase 0.005 0.0066 0.0148
Brugia malayi Nuclear hormone receptor family member nhr-31 0.0136 0.0333 0.0712
Brugia malayi Neurotransmitter-gated ion-channel transmembrane region family protein 0.0043 0.0045 0.0096
Schistosoma mansoni tar DNA-binding protein 0.0128 0.0307 0.1169
Onchocerca volvulus Neurogenic locus notch homolog 0.0229 0.0618 0.0575
Echinococcus multilocularis 7TM GPCR, rhodopsin 0.0059 0.0095 0.0362
Echinococcus multilocularis tissue type plasminogen activator 0.0194 0.051 0.1943
Onchocerca volvulus 0.0059 0.0095 0.0051
Toxoplasma gondii glycosyl hydrolase, family 31 protein 0.0035 0.002 0.0327
Schistosoma mansoni nAChR subunit (ShAR1-beta-like) 0.0043 0.0045 0.0171
Echinococcus multilocularis serotonin receptor 0.0059 0.0095 0.0362
Loa Loa (eye worm) ACC-1 protein 0.0043 0.0045 0.01
Brugia malayi latrophilin 2 splice variant baaae 0.0136 0.0332 0.0711
Echinococcus granulosus allatostatin A receptor 0.0059 0.0095 0.0432
Loa Loa (eye worm) hypothetical protein 0.0043 0.0045 0.01
Loa Loa (eye worm) hypothetical protein 0.0064 0.011 0.0246
Loa Loa (eye worm) hypothetical protein 0.0059 0.0095 0.0213
Echinococcus granulosus dnaJ subfamily B 0.04 0.1146 0.5199
Brugia malayi hypothetical protein 0.0059 0.0095 0.0204
Onchocerca volvulus 0.0059 0.0095 0.0051
Loa Loa (eye worm) hypothetical protein 0.0064 0.011 0.0246
Schistosoma mansoni nuclear hormone receptor nor-1/nor-2 0.0136 0.0333 0.1267
Schistosoma mansoni slit 0.0229 0.0618 0.2353
Echinococcus granulosus nicotinic acetylcholine receptor subunit alpha 8 0.0043 0.0045 0.0203
Echinococcus granulosus glycine receptor subunit alpha 1 0.0043 0.0045 0.0203
Brugia malayi G protein-coupled receptor 0.0059 0.0095 0.0204
Echinococcus granulosus thyroid hormone receptor alpha 0.0064 0.011 0.05
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0136 0.0333 0.0712
Echinococcus granulosus lysosomal alpha glucosidase 0.0159 0.0401 0.1819
Onchocerca volvulus Dopamine\/Ecdysteroid receptor homolog 0.0059 0.0095 0.0051
Echinococcus granulosus neuropeptide FF receptor 2 0.0059 0.0095 0.0432
Loa Loa (eye worm) gonadotropin-releasing hormone receptor 2 0.0059 0.0095 0.0213
Schistosoma mansoni cercarial elastase (S01 family) 0.0137 0.0335 0.1278
Schistosoma mansoni nAChR subunit (ShAR1-alpha-like) 0.0043 0.0045 0.0171
Echinococcus granulosus cpg binding protein 0.003 0.0003 0.0015
Echinococcus granulosus ecdysone induced protein 78C 0.0136 0.0333 0.1509
Schistosoma mansoni Cys-loop ligand gated ion channel subunit 0.0043 0.0045 0.0171
Loa Loa (eye worm) nicotinic acetylcholine receptor non-alpha subunit 0.0043 0.0045 0.01
Schistosoma mansoni alpha glucosidase 0.0035 0.002 0.0077
Brugia malayi Low-density lipoprotein receptor repeat class B containing protein 0.0095 0.0205 0.0439
Loa Loa (eye worm) nuclear receptor NHR-67 0.0064 0.011 0.0246
Brugia malayi beta-lactamase family protein 0.0072 0.0134 0.0286
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0136 0.0333 0.0712
Echinococcus multilocularis rhodopsin orphan GPCR 0.0059 0.0095 0.0362
Trichomonas vaginalis glutaminase, putative 0.0287 0.0797 1
Mycobacterium tuberculosis Conserved protein 0.0072 0.0134 0.1005
Schistosoma mansoni FTZ-F1 nuclear receptor-like protein 0.0136 0.0333 0.1267
Schistosoma mansoni nuclear hormone receptor 0.0136 0.0333 0.1267
Schistosoma mansoni cercarial elastase (S01 family) 0.0137 0.0335 0.1278
Brugia malayi gamma-aminobutyric-acid receptor beta subunit precursor 0.0043 0.0045 0.0096
Loa Loa (eye worm) hypothetical protein 0.0136 0.0333 0.0743
Trypanosoma cruzi hypothetical protein, conserved 0.0035 0.002 0.0396
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0059 0.0095 0.0362
Loa Loa (eye worm) bone morphogenetic protein 1b 0.0095 0.0205 0.0459
Echinococcus granulosus biogenic amine 5HT receptor 0.0059 0.0095 0.0432
Onchocerca volvulus 0.0059 0.0095 0.0051
Echinococcus multilocularis g protein coupled receptor 0.0059 0.0095 0.0362
Echinococcus multilocularis neurogenic locus notch protein 0.0229 0.0618 0.2353
Leishmania major hypothetical protein, conserved 0.0194 0.051 1
Echinococcus multilocularis Nuclear hormone receptor HR96 0.0064 0.011 0.042
Echinococcus multilocularis neuropeptide s receptor 0.0509 0.1483 0.5651
Schistosoma mansoni biogenic amine receptor 0.0059 0.0095 0.0362
Loa Loa (eye worm) hypothetical protein 0.0059 0.0095 0.0213
Schistosoma mansoni neuropeptide F-like receptor 0.0059 0.0095 0.0362
Loa Loa (eye worm) hypothetical protein 0.0229 0.0618 0.138
Brugia malayi beta-lactamase 0.0072 0.0134 0.0286
Schistosoma mansoni biogenic amine receptor 0.0059 0.0095 0.0362
Schistosoma mansoni cpg binding protein 0.003 0.0003 0.0012
Toxoplasma gondii calcium binding egf domain-containing protein 0.0095 0.0205 0.3324
Echinococcus granulosus acetylcholine receptor subunit beta 1 0.0043 0.0045 0.0203
Schistosoma mansoni adenoreceptor 0.0059 0.0095 0.0362
Schistosoma mansoni hypothetical protein 0.0229 0.0618 0.2353
Loa Loa (eye worm) hypothetical protein 0.0229 0.0618 0.138
Trichomonas vaginalis penicillin-binding protein, putative 0.0072 0.0134 0.1464
Loa Loa (eye worm) nuclear hormone receptor family member nhr-41 0.0136 0.0333 0.0743
Brugia malayi Cation transporter family protein 0.0043 0.0045 0.0096
Toxoplasma gondii EGF family domain-containing protein 0.0229 0.0618 1
Brugia malayi Nuclear hormone receptor family member nhr-3 0.0136 0.0333 0.0712
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0136 0.0333 0.1509
Onchocerca volvulus Bile acid receptor homolog 0.0136 0.0333 0.0289
Schistosoma mansoni tar DNA-binding protein 0.0128 0.0307 0.1169
Schistosoma mansoni hypothetical protein 0.0035 0.0021 0.0079
Brugia malayi EGF-like domain containing protein 0.0229 0.0618 0.1321
Schistosoma mansoni amine GPCR 0.0059 0.0095 0.0362
Schistosoma mansoni Cys-loop ligand gated ion channel subunit 0.0043 0.0045 0.0171
Echinococcus multilocularis g protein coupled receptor 0.0059 0.0095 0.0362
Schistosoma mansoni thyroid hormone receptor 0.088 0.2625 1
Loa Loa (eye worm) hypothetical protein 0.0072 0.0134 0.03
Loa Loa (eye worm) hypothetical protein 0.0059 0.0095 0.0213
Echinococcus multilocularis protein jagged 1 0.0229 0.0618 0.2353
Onchocerca volvulus 0.0072 0.0134 0.0089
Onchocerca volvulus 0.0137 0.0335 0.0292
Schistosoma mansoni subfamily S1A unassigned peptidase (S01 family) 0.0137 0.0335 0.1278
Loa Loa (eye worm) hypothetical protein 0.0059 0.0095 0.0213
Loa Loa (eye worm) hypothetical protein 0.0059 0.0095 0.0213
Loa Loa (eye worm) hypothetical protein 0.0043 0.0045 0.01
Echinococcus multilocularis beta LACTamase domain containing family member 0.0072 0.0134 0.051
Schistosoma mansoni hepatocyte nuclear factor 4-alpha (hnf-4-alpha) 0.0064 0.011 0.042
Schistosoma mansoni subfamily S1A unassigned peptidase (S01 family) 0.0137 0.0335 0.1278
Brugia malayi hypothetical protein 0.0072 0.0134 0.0287
Loa Loa (eye worm) acetylcholine receptor alpha subunit 0.0043 0.0045 0.01
Brugia malayi Mitochondrial import inner membrane translocase subunit Tim17 family protein 0.0043 0.0043 0.0092
Loa Loa (eye worm) glycosyl hydrolase family 31 protein 0.0159 0.0401 0.0896
Loa Loa (eye worm) hypothetical protein 0.0043 0.0045 0.01
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0064 0.011 0.05
Echinococcus granulosus dro:myosuppressin receptor 0.0059 0.0095 0.0432
Brugia malayi Neurotransmitter-gated ion-channel ligand binding domain containing protein 0.0043 0.0045 0.0096
Schistosoma mansoni amine GPCR 0.0059 0.0095 0.0362
Echinococcus granulosus tissue type plasminogen activator 0.0194 0.051 0.2315
Echinococcus multilocularis fibropellin Ia 0.0229 0.0618 0.2353
Brugia malayi beta-lactamase family protein 0.0072 0.0134 0.0286
Schistosoma mansoni hypothetical protein 0.0063 0.0106 0.0406
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0136 0.0333 0.1509
Echinococcus granulosus sex peptide receptor 0.0059 0.0095 0.0432
Mycobacterium tuberculosis Probable esterase/lipase LipP 0.0072 0.0134 0.1005
Echinococcus granulosus diuretic hormone 44 receptor GPRdih2 0.0063 0.0106 0.0483
Loa Loa (eye worm) hypothetical protein 0.0059 0.0095 0.0213
Echinococcus multilocularis growth hormone secretagogue receptor type 1 0.0059 0.0095 0.0362
Loa Loa (eye worm) G-protein coupled receptor 0.0059 0.0095 0.0213
Onchocerca volvulus 0.0059 0.0095 0.0051
Echinococcus granulosus nicotinic acetylcholine receptor alpha subunit 0.0043 0.0045 0.0203
Echinococcus multilocularis cadherin EGF LAG seven pass G type receptor 0.0063 0.0106 0.0406
Schistosoma mansoni hypothetical protein 0.0229 0.0618 0.2353
Entamoeba histolytica hypothetical protein 0.0035 0.0021 1
Schistosoma mansoni hypothetical protein 0.0063 0.0106 0.0406
Brugia malayi Trypsin family protein 0.0137 0.0335 0.0718
Loa Loa (eye worm) glutaminase 2 0.0287 0.0797 0.178
Onchocerca volvulus 0.0229 0.0618 0.0575
Echinococcus multilocularis neuropeptide receptor 0.0059 0.0095 0.0362
Plasmodium vivax hypothetical protein, conserved 0.0072 0.0134 0.2624
Schistosoma mansoni subfamily S1A unassigned peptidase (S01 family) 0.0137 0.0335 0.1278
Loa Loa (eye worm) hypothetical protein 0.0059 0.0095 0.0213
Trichomonas vaginalis D-aminoacylase, putative 0.0072 0.0134 0.1464
Schistosoma mansoni hypothetical protein 0.0229 0.0618 0.2353
Loa Loa (eye worm) 5-hydroxytryptamine 2C receptor 0.0059 0.0095 0.0213
Echinococcus multilocularis Nuclear hormone receptor family member nhr 41 0.0136 0.0333 0.1267
Echinococcus multilocularis fmrfamide receptor 0.0059 0.0095 0.0362
Echinococcus granulosus rhodopsin orphan GPCR 0.0059 0.0095 0.0432
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0072 0.0134 0.051
Onchocerca volvulus 0.0059 0.0095 0.0051
Echinococcus granulosus glycoprotein Antigen 5 0.0137 0.0335 0.1522
Onchocerca volvulus Protein ultraspiracle homolog 0.0136 0.0333 0.0289
Loa Loa (eye worm) hypothetical protein 0.0059 0.0095 0.0213
Schistosoma mansoni alpha-glucosidase 0.0137 0.0333 0.1268
Echinococcus granulosus Mastin 0.0137 0.0335 0.1522
Brugia malayi nicotinic acetylcholine receptor beta-1 chain precursor 0.0043 0.0045 0.0096
Brugia malayi acetylcholine receptor, alpha-type subunit unc-38 precursor 0.0043 0.0045 0.0096
Echinococcus granulosus glycine receptor subunit alpha 1 0.0043 0.0045 0.0203
Echinococcus granulosus g protein coupled receptor 0.0059 0.0095 0.0432
Echinococcus granulosus protein jagged 1 0.0229 0.0618 0.2802
Loa Loa (eye worm) hypothetical protein 0.0043 0.0045 0.01
Schistosoma mansoni cercarial elastase (S01 family) 0.0137 0.0335 0.1278
Loa Loa (eye worm) hypothetical protein 0.0229 0.0618 0.138
Echinococcus granulosus tm gpcr rhodopsin 0.0059 0.0095 0.0432
Brugia malayi hypothetical protein 0.0137 0.0335 0.0718
Loa Loa (eye worm) hypothetical protein 0.1472 0.4451 0.9947
Loa Loa (eye worm) hypothetical protein 0.0059 0.0095 0.0213
Schistosoma mansoni neuropeptide receptor 0.0059 0.0095 0.0362
Loa Loa (eye worm) hypothetical protein 0.0095 0.0205 0.0459
Brugia malayi photoreceptor-specific nuclear receptor 0.0136 0.0333 0.0712
Schistosoma mansoni transcription factor LCR-F1 0.0035 0.0021 0.0079
Loa Loa (eye worm) nuclear hormone receptor 0.0064 0.011 0.0246
Loa Loa (eye worm) hypothetical protein 0.0136 0.0333 0.0743
Brugia malayi Cadherin domain containing protein 0.0229 0.0618 0.1321
Brugia malayi MAP kinase sur-1 0.005 0.0066 0.0141
Brugia malayi hypothetical protein 0.0059 0.0095 0.0204
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0059 0.0095 0.0362
Onchocerca volvulus 0.0194 0.051 0.0467
Echinococcus granulosus nicotinic acetylcholine receptor subunit type 0.0043 0.0045 0.0203
Schistosoma mansoni hypothetical protein 0.0059 0.0095 0.0362
Brugia malayi putative neuropeptide receptor NPR1 0.0059 0.0095 0.0204
Schistosoma mansoni tar DNA-binding protein 0.0128 0.0307 0.1169
Loa Loa (eye worm) hypothetical protein 0.0059 0.0095 0.0213
Echinococcus granulosus g protein coupled receptor 0.0059 0.0095 0.0432
Echinococcus granulosus tachykinin peptides receptor 99D 0.0059 0.0095 0.0432
Loa Loa (eye worm) RNA recognition domain-containing protein domain-containing protein 0.0128 0.0307 0.0686
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0059 0.0095 0.0362
Trichomonas vaginalis CMGC family protein kinase 0.005 0.0066 0.0592
Echinococcus multilocularis EGFP:Bcl2 fusion protein 0.0057 0.0087 0.0333
Leishmania major hypothetical protein, conserved 0.0072 0.0134 0.2624
Schistosoma mansoni notch 0.0229 0.0618 0.2353
Loa Loa (eye worm) hypothetical protein 0.0095 0.0205 0.0459
Echinococcus multilocularis glycine receptor subunit beta 0.0043 0.0045 0.0171
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0059 0.0095 0.0362
Trichomonas vaginalis penicillin-binding protein, putative 0.0072 0.0134 0.1464
Loa Loa (eye worm) glycosyl hydrolase family 31 protein 0.0035 0.002 0.0045
Echinococcus granulosus FTZ F1 nuclear receptor protein 0.0136 0.0333 0.1509
Loa Loa (eye worm) hypothetical protein 0.0229 0.0618 0.138
Schistosoma mansoni myosin xvIII 0.0059 0.0095 0.0362
Toxoplasma gondii calcium binding egf domain-containing protein 0.0095 0.0205 0.3324
Toxoplasma gondii mitochondrial import inner membrane translocase subunit TIM10, putative 0.005 0.0066 0.1072
Trichomonas vaginalis esterase, putative 0.0072 0.0134 0.1464
Entamoeba histolytica hypothetical protein 0.0035 0.0021 1
Schistosoma mansoni nAChR subunit 0.0043 0.0045 0.0171
Loa Loa (eye worm) hypothetical protein 0.0072 0.0134 0.03
Brugia malayi Dopamine receptor protein 1 0.0059 0.0095 0.0204
Brugia malayi hypothetical protein 0.0038 0.003 0.0064
Loa Loa (eye worm) hypothetical protein 0.0064 0.011 0.0246
Loa Loa (eye worm) hypothetical protein 0.0136 0.0332 0.0743
Loa Loa (eye worm) hypothetical protein 0.0072 0.0134 0.03
Schistosoma mansoni opsin-like receptor 0.0059 0.0095 0.0362
Echinococcus multilocularis rhodopsin orphan GPCR 0.0059 0.0095 0.0362
Trypanosoma cruzi hypothetical protein, conserved 0.0194 0.051 1
Schistosoma mansoni hypothetical protein 0.0194 0.051 0.1943
Echinococcus granulosus 7tm_1 domain containing protein 0.0059 0.0095 0.0432
Loa Loa (eye worm) hypothetical protein 0.0072 0.0134 0.0299
Brugia malayi Apoptosis regulator proteins, Bcl-2 family protein 0.0057 0.0087 0.0187
Trypanosoma brucei protein kinase, putative 0.005 0.0066 0.4939
Echinococcus granulosus neuropeptide receptor 0.0059 0.0095 0.0432
Schistosoma mansoni subfamily S1A unassigned peptidase (S01 family) 0.0137 0.0335 0.1278
Echinococcus granulosus tm gpcr rhodopsin 0.0059 0.0095 0.0432
Brugia malayi GnHR receptor homolog 0.0059 0.0095 0.0204
Plasmodium falciparum mitochondrial import inner membrane translocase subunit TIM10, putative 0.005 0.0066 0.1297
Loa Loa (eye worm) steroid hormone receptor 0.0136 0.0333 0.0743
Echinococcus multilocularis g protein linked acetylcholine receptor gar 2a 0.0059 0.0095 0.0362
Brugia malayi excitatory GABA receptor EXP-1A 0.0043 0.0045 0.0096
Echinococcus multilocularis hepatocyte nuclear factor 4 alpha 0.0136 0.0333 0.1267
Giardia lamblia High cysteine protein 0.0229 0.0618 1
Echinococcus granulosus rhodopsin orphan GPCR 0.0059 0.0095 0.0432
Echinococcus granulosus Nuclear hormone receptor HR96 0.0064 0.011 0.05
Loa Loa (eye worm) Notch2 0.0229 0.0618 0.138
Brugia malayi Neurotransmitter-gated ion-channel transmembrane region family protein 0.0043 0.0045 0.0096
Brugia malayi Corticotropin releasing factor receptor 2 precursor, putative 0.02 0.0527 0.1128
Loa Loa (eye worm) hypothetical protein 0.0043 0.0045 0.01
Echinococcus granulosus FTZ F1 alpha 0.0136 0.0333 0.1509
Schistosoma mansoni nAChR subunit (ShAR1-beta2-like) 0.0043 0.0045 0.0171
Loa Loa (eye worm) hypothetical protein 0.0043 0.0045 0.01

Activities

Activity type Activity value Assay description Source Reference
IC50 (binding) = 280 nM CGRP1 receptor affinity on human neuroblastoma cells SK-N-MC, which selectively express the human CGRP1 receptor. ChEMBL. 9438028
IC50 (binding) = 280 nM CGRP1 receptor affinity on human neuroblastoma cells SK-N-MC, which selectively express the human CGRP1 receptor. ChEMBL. 9438028

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
In any case, if you have information about papers containing relevant validation data for this target, please log in using your TDR Targets username and password and send them to us using the corresponding form in this page (only visible to registered users) or contact us.

External resources for this compound

No external resources registered for this compound

Bibliographic References

1 literature reference was collected for this gene.

If you have references for this compound, please enter them in a user comment (below) or Contact us.