Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Brugia malayi | neuropeptide F receptor | 0.0955 | 0.6599 | 1 |
Echinococcus granulosus | 7tm_1 domain containing protein | 0.0955 | 0.6599 | 0.6599 |
Brugia malayi | photoreceptor-specific nuclear receptor | 0.0217 | 0.0725 | 0.0984 |
Echinococcus multilocularis | serotonin receptor | 0.0955 | 0.6599 | 0.7534 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-31 | 0.0217 | 0.0725 | 0.1099 |
Echinococcus granulosus | fmrfamide receptor | 0.0955 | 0.6599 | 0.6599 |
Brugia malayi | Immunoglobulin I-set domain containing protein | 0.015 | 0.0189 | 0.016 |
Onchocerca volvulus | 0.0955 | 0.6599 | 1 | |
Echinococcus multilocularis | rhodopsin orphan GPCR | 0.0955 | 0.6599 | 0.7534 |
Brugia malayi | Nuclear hormone receptor family member nhr-1 | 0.0217 | 0.0725 | 0.0984 |
Loa Loa (eye worm) | hypothetical protein | 0.0955 | 0.6599 | 1 |
Schistosoma mansoni | thyroid hormone receptor | 0.0217 | 0.0725 | 0.0725 |
Schistosoma mansoni | photoreceptor-specific nuclear receptor related | 0.0217 | 0.0725 | 0.0725 |
Brugia malayi | GnHR receptor homolog | 0.0955 | 0.6599 | 1 |
Onchocerca volvulus | 0.0955 | 0.6599 | 1 | |
Schistosoma mansoni | biogenic amine (dopamine) receptor | 0.0955 | 0.6599 | 0.6599 |
Brugia malayi | Dopamine receptor protein 2 | 0.0955 | 0.6599 | 1 |
Brugia malayi | Ligand-binding domain of nuclear hormone receptor family protein | 0.0217 | 0.0725 | 0.0984 |
Echinococcus multilocularis | Nuclear hormone receptor family member nhr 41 | 0.0217 | 0.0725 | 0.0742 |
Schistosoma mansoni | myosin xvIII | 0.0955 | 0.6599 | 0.6599 |
Brugia malayi | G-protein coupled receptor | 0.0955 | 0.6599 | 1 |
Schistosoma mansoni | rhodopsin-like orphan GPCR | 0.0955 | 0.6599 | 0.6599 |
Schistosoma mansoni | rhodopsin-like orphan GPCR | 0.0955 | 0.6599 | 0.6599 |
Brugia malayi | putative neuropeptide receptor NPR1 | 0.0955 | 0.6599 | 1 |
Schistosoma mansoni | rhodopsin-like orphan GPCR | 0.0955 | 0.6599 | 0.6599 |
Echinococcus multilocularis | neuropeptide receptor | 0.0955 | 0.6599 | 0.7534 |
Echinococcus granulosus | nuclear receptor 2DBD gamma | 0.0217 | 0.0725 | 0.0725 |
Brugia malayi | hypothetical protein | 0.0955 | 0.6599 | 1 |
Echinococcus multilocularis | pyroglutamylated rfamide peptide receptor | 0.0955 | 0.6599 | 0.7534 |
Echinococcus multilocularis | serotonin receptor | 0.0955 | 0.6599 | 0.7534 |
Brugia malayi | hypothetical protein | 0.0955 | 0.6599 | 1 |
Onchocerca volvulus | 0.0955 | 0.6599 | 1 | |
Echinococcus granulosus | tm gpcr rhodopsin | 0.0955 | 0.6599 | 0.6599 |
Echinococcus multilocularis | rhodopsin orphan GPCR | 0.0955 | 0.6599 | 0.7534 |
Schistosoma mansoni | alpha-1 adrenergic receptor | 0.0955 | 0.6599 | 0.6599 |
Schistosoma mansoni | retinoic acid receptor RXR | 0.1382 | 1 | 1 |
Schistosoma mansoni | amine GPCR | 0.0955 | 0.6599 | 0.6599 |
Echinococcus granulosus | tm gpcr rhodopsin | 0.0955 | 0.6599 | 0.6599 |
Loa Loa (eye worm) | hypothetical protein | 0.0955 | 0.6599 | 1 |
Echinococcus multilocularis | peptide (allatostatin:somatostatin) | 0.0955 | 0.6599 | 0.7534 |
Loa Loa (eye worm) | hypothetical protein | 0.0955 | 0.6599 | 1 |
Echinococcus granulosus | alpha 1A adrenergic receptor | 0.0955 | 0.6599 | 0.6599 |
Trichomonas vaginalis | ribonucleoside-diphosphate reductase alpha chain, putative | 0.0136 | 0.0084 | 0.5 |
Echinococcus granulosus | thyrotropin releasing hormone receptor | 0.0955 | 0.6599 | 0.6599 |
Schistosoma mansoni | rhodopsin-like orphan GPCR | 0.0955 | 0.6599 | 0.6599 |
Loa Loa (eye worm) | hypothetical protein | 0.0217 | 0.0725 | 0.1099 |
Echinococcus granulosus | biogenic amine 5HT receptor | 0.0955 | 0.6599 | 0.6599 |
Echinococcus multilocularis | neuropeptide receptor A26 | 0.0955 | 0.6599 | 0.7534 |
Brugia malayi | larval opioid receptor | 0.0955 | 0.6599 | 1 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-1 | 0.0217 | 0.0725 | 0.1099 |
Schistosoma mansoni | tyrosine kinase | 0.0221 | 0.0761 | 0.0761 |
Brugia malayi | Immunoglobulin I-set domain containing protein | 0.0769 | 0.5118 | 0.7726 |
Echinococcus multilocularis | FTZ F1 alpha | 0.0217 | 0.0725 | 0.0742 |
Loa Loa (eye worm) | hypothetical protein | 0.0955 | 0.6599 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0955 | 0.6599 | 1 |
Schistosoma mansoni | rhodopsin-like orphan GPCR | 0.0955 | 0.6599 | 0.6599 |
Schistosoma mansoni | ancient conserved domain protein 2 (cyclin m2) | 0.0955 | 0.6599 | 0.6599 |
Echinococcus multilocularis | tm gpcr rhodopsin gpcr rhodopsin superfamily | 0.0955 | 0.6599 | 0.7534 |
Onchocerca volvulus | 0.0955 | 0.6599 | 1 | |
Echinococcus granulosus | dro:myosuppressin receptor | 0.0955 | 0.6599 | 0.6599 |
Echinococcus multilocularis | 0.0206 | 0.0637 | 0.0639 | |
Schistosoma mansoni | peptide (FMRFamide/somatostatin)-like receptor | 0.0955 | 0.6599 | 0.6599 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-40 | 0.0217 | 0.0725 | 0.1099 |
Brugia malayi | Nuclear hormone receptor family member nhr-25 | 0.0217 | 0.0725 | 0.0984 |
Brugia malayi | ORL1-like opioid receptor | 0.0955 | 0.6599 | 1 |
Echinococcus granulosus | melanoma receptor tyrosine protein kinase | 0.0366 | 0.1913 | 0.1913 |
Brugia malayi | neuropeptide F receptor | 0.0955 | 0.6599 | 1 |
Brugia malayi | hypothetical protein | 0.0159 | 0.0266 | 0.0279 |
Schistosoma mansoni | nuclear receptor 2DBD-gamma | 0.0217 | 0.0725 | 0.0725 |
Plasmodium falciparum | ribonucleoside-diphosphate reductase large subunit, putative | 0.0136 | 0.0084 | 0.5 |
Brugia malayi | Nuclear hormone receptor family member nhr-14 | 0.0217 | 0.0725 | 0.0984 |
Echinococcus multilocularis | biogenic amine (5HT) receptor | 0.0955 | 0.6599 | 0.7534 |
Loa Loa (eye worm) | hypothetical protein | 0.0955 | 0.6599 | 1 |
Brugia malayi | nuclear receptor NHR-88 | 0.0217 | 0.0725 | 0.0984 |
Schistosoma mansoni | growth hormone secretagogue receptor | 0.0955 | 0.6599 | 0.6599 |
Echinococcus granulosus | neuropeptides capa receptor | 0.0955 | 0.6599 | 0.6599 |
Leishmania major | ribonucleoside-diphosphate reductase large chain, putative | 0.0136 | 0.0084 | 0.5 |
Echinococcus granulosus | serotonin receptor | 0.0955 | 0.6599 | 0.6599 |
Schistosoma mansoni | neuropeptide f receptor 76f | 0.0955 | 0.6599 | 0.6599 |
Schistosoma mansoni | histamine h1 receptor | 0.0955 | 0.6599 | 0.6599 |
Echinococcus multilocularis | g protein coupled receptor | 0.0955 | 0.6599 | 0.7534 |
Loa Loa (eye worm) | hypothetical protein | 0.0955 | 0.6599 | 1 |
Treponema pallidum | ribonucleotide-diphosphate reductase subunit alpha | 0.0136 | 0.0084 | 0.5 |
Loa Loa (eye worm) | hypothetical protein | 0.0955 | 0.6599 | 1 |
Schistosoma mansoni | amine GPCR | 0.0955 | 0.6599 | 0.6599 |
Echinococcus granulosus | nuclear receptor subfamily 1 group D | 0.0159 | 0.0266 | 0.0266 |
Schistosoma mansoni | peptide (FMRFamide/somatostatin)-like receptor | 0.0955 | 0.6599 | 0.6599 |
Schistosoma mansoni | tyrosine kinase | 0.0221 | 0.0761 | 0.0761 |
Brugia malayi | G-protein-linked acetylcholine receptor protein 2, putative | 0.0955 | 0.6599 | 1 |
Brugia malayi | Melatonin receptor type 1A | 0.0955 | 0.6599 | 1 |
Echinococcus multilocularis | allatostatin A receptor | 0.0955 | 0.6599 | 0.7534 |
Echinococcus multilocularis | neuropeptide Y receptor | 0.0955 | 0.6599 | 0.7534 |
Loa Loa (eye worm) | hypothetical protein | 0.0955 | 0.6599 | 1 |
Onchocerca volvulus | 0.0955 | 0.6599 | 1 | |
Toxoplasma gondii | ribonucleoside-diphosphate reductase large chain | 0.0136 | 0.0084 | 0.5 |
Echinococcus granulosus | neuropeptide receptor | 0.0955 | 0.6599 | 0.6599 |
Trypanosoma brucei | ribonucleoside-diphosphate reductase large chain | 0.0136 | 0.0084 | 0.5 |
Echinococcus granulosus | rhodopsin orphan GPCR | 0.0955 | 0.6599 | 0.6599 |
Loa Loa (eye worm) | hypothetical protein | 0.0217 | 0.0725 | 0.1099 |
Echinococcus granulosus | tm gpcr rhodopsin | 0.0955 | 0.6599 | 0.6599 |
Schistosoma mansoni | amine GPCR | 0.0955 | 0.6599 | 0.6599 |
Brugia malayi | putative neuropeptide receptor | 0.0955 | 0.6599 | 1 |
Echinococcus multilocularis | g protein coupled receptor | 0.0955 | 0.6599 | 0.7534 |
Loa Loa (eye worm) | neuropeptide F receptor | 0.0955 | 0.6599 | 1 |
Echinococcus granulosus | g protein coupled receptor | 0.0955 | 0.6599 | 0.6599 |
Schistosoma mansoni | rhodopsin-like orphan GPCR | 0.0955 | 0.6599 | 0.6599 |
Echinococcus multilocularis | nuclear receptor 2DBD gamma | 0.0217 | 0.0725 | 0.0742 |
Brugia malayi | nuclear receptor RXR | 0.0159 | 0.0266 | 0.0279 |
Brugia malayi | Furin-like cysteine rich region family protein | 0.0674 | 0.4363 | 0.6567 |
Brugia malayi | Dopamine receptor protein 1 | 0.0955 | 0.6599 | 1 |
Echinococcus granulosus | sex peptide receptor | 0.0955 | 0.6599 | 0.6599 |
Echinococcus multilocularis | nuclear receptor 2DBD gamma | 0.0217 | 0.0725 | 0.0742 |
Echinococcus granulosus | neuropeptide Y receptor | 0.0955 | 0.6599 | 0.6599 |
Brugia malayi | Nuclear hormone receptor family member nhr-25 | 0.0217 | 0.0725 | 0.0984 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-41 | 0.0217 | 0.0725 | 0.1099 |
Brugia malayi | Serotonin receptor | 0.0955 | 0.6599 | 1 |
Echinococcus multilocularis | somatostatin receptor | 0.0955 | 0.6599 | 0.7534 |
Loa Loa (eye worm) | hypothetical protein | 0.0955 | 0.6599 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0955 | 0.6599 | 1 |
Schistosoma mansoni | rhodopsin-like orphan GPCR | 0.0955 | 0.6599 | 0.6599 |
Echinococcus multilocularis | nuclear receptor subfamily 1 group D | 0.0159 | 0.0266 | 0.021 |
Schistosoma mansoni | tyrosine kinase | 0.0674 | 0.4363 | 0.4363 |
Echinococcus multilocularis | G-protein coupled receptor, putative | 0.0955 | 0.6599 | 0.7534 |
Echinococcus granulosus | epidermal growth factor receptor | 0.0366 | 0.1913 | 0.1913 |
Brugia malayi | Nuclear hormone receptor family member nhr-49 | 0.0217 | 0.0725 | 0.0984 |
Onchocerca volvulus | 0.0955 | 0.6599 | 1 | |
Echinococcus multilocularis | roundabout 2 | 0.0151 | 0.02 | 0.0134 |
Loa Loa (eye worm) | hypothetical protein | 0.0955 | 0.6599 | 1 |
Brugia malayi | hypothetical protein | 0.0955 | 0.6599 | 1 |
Schistosoma mansoni | biogenic amine receptor | 0.0955 | 0.6599 | 0.6599 |
Brugia malayi | Nuclear hormone receptor-like 1 | 0.0159 | 0.0266 | 0.0279 |
Brugia malayi | G-protein coupled receptor | 0.0955 | 0.6599 | 1 |
Schistosoma mansoni | ecdysone-induced protein 78c (dr-78) | 0.0159 | 0.0266 | 0.0266 |
Brugia malayi | Nuclear hormone receptor family member nhr-19 | 0.0217 | 0.0725 | 0.0984 |
Brugia malayi | Dopamine receptor protein 1, putative (partial) | 0.0955 | 0.6599 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0217 | 0.0725 | 0.1099 |
Brugia malayi | hypothetical protein | 0.0955 | 0.6599 | 1 |
Schistosoma mansoni | coup transcription factor | 0.0217 | 0.0725 | 0.0725 |
Brugia malayi | Tachykinin-like peptides receptor 99D | 0.0955 | 0.6599 | 1 |
Brugia malayi | Unidentified vitellogenin-linked transcript protein 6, putative | 0.0955 | 0.6599 | 1 |
Schistosoma mansoni | neuropeptide receptor | 0.0955 | 0.6599 | 0.6599 |
Brugia malayi | ecdysteroid receptor | 0.0366 | 0.1913 | 0.2807 |
Echinococcus multilocularis | growth hormone secretagogue receptor type 1 | 0.0955 | 0.6599 | 0.7534 |
Onchocerca volvulus | 0.0955 | 0.6599 | 1 | |
Schistosoma mansoni | retinoid-x-receptor (RXR) | 0.0159 | 0.0266 | 0.0266 |
Brugia malayi | hypothetical protein | 0.0955 | 0.6599 | 1 |
Schistosoma mansoni | Tr4/Tr2 (homologue) | 0.0217 | 0.0725 | 0.0725 |
Onchocerca volvulus | Tyrosine kinase homolog | 0.0668 | 0.4315 | 0.6112 |
Loa Loa (eye worm) | hypothetical protein | 0.0955 | 0.6599 | 1 |
Echinococcus multilocularis | rhodopsin orphan GPCR | 0.0955 | 0.6599 | 0.7534 |
Echinococcus granulosus | epidermal growth factor receptor | 0.0674 | 0.4363 | 0.4363 |
Loa Loa (eye worm) | hypothetical protein | 0.0955 | 0.6599 | 1 |
Onchocerca volvulus | Dopamine\/Ecdysteroid receptor homolog | 0.0955 | 0.6599 | 1 |
Echinococcus granulosus | biogenic amine 5HT receptor | 0.0955 | 0.6599 | 0.6599 |
Echinococcus multilocularis | G protein coupled receptor 139 | 0.0955 | 0.6599 | 0.7534 |
Echinococcus granulosus | 7TM GPCR rhodopsin | 0.0955 | 0.6599 | 0.6599 |
Loa Loa (eye worm) | hypothetical protein | 0.0955 | 0.6599 | 1 |
Brugia malayi | hypothetical protein | 0.0955 | 0.6599 | 1 |
Schistosoma mansoni | opsin-like receptor | 0.0955 | 0.6599 | 0.6599 |
Echinococcus multilocularis | rhodopsin orphan GPCR | 0.0955 | 0.6599 | 0.7534 |
Echinococcus granulosus | ribonucleoside diphosphate reductase large | 0.0136 | 0.0084 | 0.0084 |
Onchocerca volvulus | 0.0955 | 0.6599 | 1 | |
Echinococcus multilocularis | neuropeptide s receptor | 0.0955 | 0.6599 | 0.7534 |
Schistosoma mansoni | tyrosine kinase | 0.0353 | 0.1812 | 0.1812 |
Loa Loa (eye worm) | unidentified vitellogenin-linked transcript protein 6 | 0.0955 | 0.6599 | 1 |
Schistosoma mansoni | tyrosine kinase | 0.0366 | 0.1913 | 0.1913 |
Echinococcus granulosus | g protein coupled receptor | 0.0955 | 0.6599 | 0.6599 |
Mycobacterium leprae | SECRETED ANTIGEN 85-C FBPC (85C) (ANTIGEN 85 COMPLEX C) (AG58C) (MYCOLYL TRANSFERASE 85C) (FIBRONECTIN-BINDING PROTEIN C) | 0.0826 | 0.5577 | 1 |
Echinococcus granulosus | roundabout 2 | 0.0151 | 0.02 | 0.02 |
Brugia malayi | Nuclear hormone receptor family member nhr-41 | 0.0217 | 0.0725 | 0.0984 |
Echinococcus multilocularis | neuropeptide Y receptor | 0.0955 | 0.6599 | 0.7534 |
Echinococcus granulosus | pyroglutamylated rfamide peptide receptor | 0.0955 | 0.6599 | 0.6599 |
Loa Loa (eye worm) | hypothetical protein | 0.0366 | 0.1913 | 0.2898 |
Mycobacterium tuberculosis | Secreted antigen 85-C FbpC (85C) (antigen 85 complex C) (AG58C) (mycolyl transferase 85C) (fibronectin-binding protein C) | 0.0826 | 0.5577 | 1 |
Schistosoma mansoni | muscarinic acetylcholine (GAR) receptor | 0.0955 | 0.6599 | 0.6599 |
Schistosoma mansoni | rhodopsin-like orphan GPCR | 0.0955 | 0.6599 | 0.6599 |
Schistosoma mansoni | hypothetical protein | 0.0955 | 0.6599 | 0.6599 |
Loa Loa (eye worm) | hypothetical protein | 0.0151 | 0.02 | 0.0302 |
Echinococcus granulosus | rhodopsin orphan GPCR | 0.0955 | 0.6599 | 0.6599 |
Echinococcus multilocularis | tm gpcr rhodopsin gpcr rhodopsin superfamily | 0.0955 | 0.6599 | 0.7534 |
Echinococcus multilocularis | rhodopsin orphan GPCR | 0.0955 | 0.6599 | 0.7534 |
Echinococcus multilocularis | g protein coupled receptor | 0.0955 | 0.6599 | 0.7534 |
Echinococcus multilocularis | tm gpcr rhodopsin gpcr rhodopsin superfamily | 0.0955 | 0.6599 | 0.7534 |
Schistosoma mansoni | peptide (allatostatin/somatostatin)-like receptor | 0.0955 | 0.6599 | 0.6599 |
Echinococcus multilocularis | fmrfamide receptor | 0.0955 | 0.6599 | 0.7534 |
Schistosoma mansoni | biogenic amine (5HT) receptor | 0.0955 | 0.6599 | 0.6599 |
Echinococcus granulosus | hepatocyte nuclear factor 4 alpha | 0.0217 | 0.0725 | 0.0725 |
Schistosoma mansoni | rhodopsin-like orphan GPCR | 0.0955 | 0.6599 | 0.6599 |
Loa Loa (eye worm) | hypothetical protein | 0.0955 | 0.6599 | 1 |
Echinococcus granulosus | somatostatin receptor | 0.0955 | 0.6599 | 0.6599 |
Loa Loa (eye worm) | hypothetical protein | 0.0955 | 0.6599 | 1 |
Echinococcus granulosus | g protein linked acetylcholine receptor gar 2a | 0.0955 | 0.6599 | 0.6599 |
Schistosoma mansoni | biogenic amine (octopamine/dopamine) receptor | 0.0955 | 0.6599 | 0.6599 |
Echinococcus granulosus | rhodopsin orphan GPCR | 0.0955 | 0.6599 | 0.6599 |
Schistosoma mansoni | hypothetical protein | 0.0955 | 0.6599 | 0.6599 |
Echinococcus multilocularis | G protein coupled 5 hydroxytryptamine receptor | 0.0955 | 0.6599 | 0.7534 |
Brugia malayi | hypothetical protein | 0.0955 | 0.6599 | 1 |
Echinococcus granulosus | peptide allatostatin:somatostatin | 0.0955 | 0.6599 | 0.6599 |
Echinococcus granulosus | insulin growth factor 1 receptor beta | 0.0221 | 0.0761 | 0.0761 |
Echinococcus multilocularis | thyrotropin releasing hormone receptor | 0.0955 | 0.6599 | 0.7534 |
Schistosoma mansoni | opsin-like receptor | 0.0955 | 0.6599 | 0.6599 |
Onchocerca volvulus | 0.0955 | 0.6599 | 1 | |
Schistosoma mansoni | opsin-like receptor | 0.0955 | 0.6599 | 0.6599 |
Brugia malayi | Protein kinase domain containing protein | 0.0221 | 0.0761 | 0.1038 |
Loa Loa (eye worm) | hypothetical protein | 0.0955 | 0.6599 | 1 |
Loa Loa (eye worm) | G-protein coupled receptor | 0.0955 | 0.6599 | 1 |
Brugia malayi | Nuclear hormone receptor family member nhr-40 | 0.0217 | 0.0725 | 0.0984 |
Schistosoma mansoni | biogenic amine (dopamine) receptor | 0.0955 | 0.6599 | 0.6599 |
Schistosoma mansoni | nuclear hormone receptor nor-1/nor-2 | 0.0217 | 0.0725 | 0.0725 |
Loa Loa (eye worm) | hypothetical protein | 0.0955 | 0.6599 | 1 |
Echinococcus multilocularis | fmrfamide receptor | 0.0955 | 0.6599 | 0.7534 |
Schistosoma mansoni | neuropeptide F-like receptor | 0.0955 | 0.6599 | 0.6599 |
Schistosoma mansoni | tyrosine kinase | 0.0353 | 0.1812 | 0.1812 |
Echinococcus granulosus | rhodopsin orphan GPCR | 0.0955 | 0.6599 | 0.6599 |
Brugia malayi | Serotonin/octopamine receptor family protein 7 | 0.0955 | 0.6599 | 1 |
Echinococcus multilocularis | insulin growth factor 1 receptor beta | 0.0221 | 0.0761 | 0.0782 |
Schistosoma mansoni | tyrosine kinase | 0.0353 | 0.1812 | 0.1812 |
Loa Loa (eye worm) | hypothetical protein | 0.0955 | 0.6599 | 1 |
Echinococcus multilocularis | neuropeptides capa receptor | 0.0955 | 0.6599 | 0.7534 |
Brugia malayi | nuclear hormone receptor | 0.0217 | 0.0725 | 0.0984 |
Brugia malayi | hypothetical protein | 0.0955 | 0.6599 | 1 |
Echinococcus multilocularis | rhodopsin orphan GPCR | 0.0955 | 0.6599 | 0.7534 |
Loa Loa (eye worm) | nuclear Hormone Receptor family member | 0.0217 | 0.0725 | 0.1099 |
Brugia malayi | Nuclear hormone receptor-like 1 | 0.0159 | 0.0266 | 0.0279 |
Onchocerca volvulus | Neuropeptide F receptor homolog | 0.0955 | 0.6599 | 1 |
Echinococcus multilocularis | FTZ F1 nuclear receptor protein | 0.0217 | 0.0725 | 0.0742 |
Onchocerca volvulus | 0.0955 | 0.6599 | 1 | |
Echinococcus multilocularis | g-protein coupled receptor | 0.0955 | 0.6599 | 0.7534 |
Echinococcus multilocularis | orexin receptor type 2 | 0.0955 | 0.6599 | 0.7534 |
Schistosoma mansoni | tyrosine kinase | 0.0366 | 0.1913 | 0.1913 |
Echinococcus multilocularis | g protein linked acetylcholine receptor gar 2a | 0.0955 | 0.6599 | 0.7534 |
Loa Loa (eye worm) | hypothetical protein | 0.0955 | 0.6599 | 1 |
Brugia malayi | hypothetical protein | 0.0159 | 0.0266 | 0.0279 |
Loa Loa (eye worm) | TK/EGFR protein kinase | 0.0674 | 0.4363 | 0.6611 |
Schistosoma mansoni | neuropeptide receptor | 0.0955 | 0.6599 | 0.6599 |
Onchocerca volvulus | Bile acid receptor homolog | 0.0366 | 0.1913 | 0.2022 |
Loa Loa (eye worm) | hypothetical protein | 0.0955 | 0.6599 | 1 |
Echinococcus granulosus | FTZ F1 alpha | 0.0217 | 0.0725 | 0.0725 |
Echinococcus multilocularis | epidermal growth factor receptor | 0.0674 | 0.4363 | 0.4947 |
Schistosoma mansoni | histamine-responsive GPCR (AAF21638) | 0.0955 | 0.6599 | 0.6599 |
Loa Loa (eye worm) | gonadotropin-releasing hormone receptor 2 | 0.0955 | 0.6599 | 1 |
Echinococcus multilocularis | neuropeptides capa receptor | 0.0955 | 0.6599 | 0.7534 |
Onchocerca volvulus | 0.063 | 0.4015 | 0.56 | |
Echinococcus granulosus | rhodopsin orphan GPCR | 0.0955 | 0.6599 | 0.6599 |
Brugia malayi | Serotonin receptor | 0.0955 | 0.6599 | 1 |
Echinococcus granulosus | rhodopsin orphan GPCR | 0.0955 | 0.6599 | 0.6599 |
Loa Loa (eye worm) | steroid hormone receptor | 0.0217 | 0.0725 | 0.1099 |
Loa Loa (eye worm) | hypothetical protein | 0.0159 | 0.0266 | 0.0403 |
Echinococcus granulosus | neuropeptide receptor | 0.0955 | 0.6599 | 0.6599 |
Echinococcus multilocularis | COUP TF:Svp nuclear hormone receptor | 0.0217 | 0.0725 | 0.0742 |
Loa Loa (eye worm) | hypothetical protein | 0.0217 | 0.0725 | 0.1099 |
Schistosoma mansoni | amine GPCR | 0.0955 | 0.6599 | 0.6599 |
Schistosoma mansoni | biogenic amine receptor | 0.0955 | 0.6599 | 0.6599 |
Brugia malayi | AKH receptor | 0.0955 | 0.6599 | 1 |
Echinococcus multilocularis | retinoic acid receptor rxr beta a retinoic acid receptor rxr alpha a retinoic acid receptor rxr alpha | 0.1223 | 0.8732 | 1 |
Loa Loa (eye worm) | neuropeptide F receptor | 0.0955 | 0.6599 | 1 |
Echinococcus granulosus | orexin receptor type 2 | 0.0955 | 0.6599 | 0.6599 |
Brugia malayi | G protein-coupled receptor | 0.0955 | 0.6599 | 1 |
Echinococcus granulosus | rhodopsin orphan GPCR | 0.0955 | 0.6599 | 0.6599 |
Onchocerca volvulus | 0.0955 | 0.6599 | 1 | |
Echinococcus granulosus | insulin receptor | 0.0221 | 0.0761 | 0.0761 |
Loa Loa (eye worm) | hypothetical protein | 0.0159 | 0.0266 | 0.0403 |
Loa Loa (eye worm) | hypothetical protein | 0.0151 | 0.02 | 0.0302 |
Loa Loa (eye worm) | TK protein kinase | 0.015 | 0.0189 | 0.0286 |
Onchocerca volvulus | 0.0955 | 0.6599 | 1 | |
Loa Loa (eye worm) | G-protein-linked acetylcholine receptor protein 2 | 0.0955 | 0.6599 | 1 |
Echinococcus multilocularis | dro:myosuppressin receptor | 0.0955 | 0.6599 | 0.7534 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-49 | 0.0217 | 0.0725 | 0.1099 |
Schistosoma mansoni | FTZ-F1 nuclear receptor-like protein | 0.0217 | 0.0725 | 0.0725 |
Echinococcus granulosus | COUP TF:Svp nuclear hormone receptor | 0.0217 | 0.0725 | 0.0725 |
Loa Loa (eye worm) | follicle stimulating hormone receptor | 0.0955 | 0.6599 | 1 |
Brugia malayi | steroid hormone receptor | 0.0217 | 0.0725 | 0.0984 |
Loa Loa (eye worm) | hypothetical protein | 0.0955 | 0.6599 | 1 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-14 | 0.0217 | 0.0725 | 0.1099 |
Schistosoma mansoni | peptide (FMRFamide/neurokinin-3)-like receptor | 0.0955 | 0.6599 | 0.6599 |
Echinococcus granulosus | g protein linked acetylcholine receptor gar 2a | 0.0955 | 0.6599 | 0.6599 |
Echinococcus multilocularis | g protein linked acetylcholine receptor gar 2a | 0.0955 | 0.6599 | 0.7534 |
Echinococcus granulosus | FTZ F1 nuclear receptor protein | 0.0217 | 0.0725 | 0.0725 |
Loa Loa (eye worm) | hypothetical protein | 0.0955 | 0.6599 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0159 | 0.0266 | 0.0403 |
Brugia malayi | Steroid receptor seven-up type 2 | 0.0217 | 0.0725 | 0.0984 |
Schistosoma mansoni | RAR-like nuclear receptor | 0.0217 | 0.0725 | 0.0725 |
Loa Loa (eye worm) | hypothetical protein | 0.0955 | 0.6599 | 1 |
Onchocerca volvulus | 0.0955 | 0.6599 | 1 | |
Loa Loa (eye worm) | hypothetical protein | 0.0159 | 0.0266 | 0.0403 |
Echinococcus multilocularis | 7TM GPCR, rhodopsin | 0.0955 | 0.6599 | 0.7534 |
Echinococcus granulosus | neuropeptide FF receptor 2 | 0.0955 | 0.6599 | 0.6599 |
Echinococcus granulosus | g-protein coupled receptor | 0.0955 | 0.6599 | 0.6599 |
Wolbachia endosymbiont of Brugia malayi | ribonucleotide-diphosphate reductase subunit alpha | 0.0136 | 0.0084 | 0.5 |
Schistosoma mansoni | ribonucleoside-diphosphate reductase alpha subunit | 0.0136 | 0.0084 | 0.0084 |
Loa Loa (eye worm) | melatonin receptor type 1A | 0.0955 | 0.6599 | 1 |
Echinococcus multilocularis | ecdysone induced protein 78C | 0.0217 | 0.0725 | 0.0742 |
Echinococcus multilocularis | rhodopsin orphan GPCR | 0.0955 | 0.6599 | 0.7534 |
Loa Loa (eye worm) | TK/KIN16 protein kinase | 0.0769 | 0.5118 | 0.7755 |
Schistosoma mansoni | neuropeptide F-like receptor | 0.0955 | 0.6599 | 0.6599 |
Echinococcus multilocularis | neuropeptide FF receptor 2 | 0.0955 | 0.6599 | 0.7534 |
Mycobacterium ulcerans | secreted antigen 85-C FbpC | 0.0826 | 0.5577 | 1 |
Echinococcus granulosus | allatostatin A receptor | 0.0955 | 0.6599 | 0.6599 |
Loa Loa (eye worm) | hypothetical protein | 0.0955 | 0.6599 | 1 |
Schistosoma mansoni | biogenic amine receptor | 0.0955 | 0.6599 | 0.6599 |
Loa Loa (eye worm) | hypothetical protein | 0.0217 | 0.0725 | 0.1099 |
Loa Loa (eye worm) | hypothetical protein | 0.0955 | 0.6599 | 1 |
Brugia malayi | hypothetical protein | 0.0955 | 0.6599 | 1 |
Brugia malayi | RE15519p | 0.0955 | 0.6599 | 1 |
Echinococcus multilocularis | hepatocyte nuclear factor 4 alpha | 0.0217 | 0.0725 | 0.0742 |
Echinococcus granulosus | growth hormone secretagogue receptor type 1 | 0.0955 | 0.6599 | 0.6599 |
Schistosoma mansoni | biogenic amine (5HT) receptor | 0.0955 | 0.6599 | 0.6599 |
Onchocerca volvulus | 0.0955 | 0.6599 | 1 | |
Loa Loa (eye worm) | hypothetical protein | 0.0955 | 0.6599 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0955 | 0.6599 | 1 |
Schistosoma mansoni | thyrotropin-releasing hormone receptor | 0.0955 | 0.6599 | 0.6599 |
Schistosoma mansoni | nuclear hormone receptor | 0.0217 | 0.0725 | 0.0725 |
Brugia malayi | hypothetical protein | 0.0955 | 0.6599 | 1 |
Echinococcus granulosus | neuropeptide s receptor | 0.0955 | 0.6599 | 0.6599 |
Schistosoma mansoni | amine GPCR | 0.0955 | 0.6599 | 0.6599 |
Onchocerca volvulus | 0.0955 | 0.6599 | 1 | |
Echinococcus multilocularis | neuropeptide receptor | 0.0955 | 0.6599 | 0.7534 |
Brugia malayi | gonadotropin-releasing hormone receptor 2 | 0.0955 | 0.6599 | 1 |
Echinococcus granulosus | neuropeptide receptor A26 | 0.0955 | 0.6599 | 0.6599 |
Chlamydia trachomatis | ribonucleoside-diphosphate reductase subunit alpha | 0.0136 | 0.0084 | 0.5 |
Loa Loa (eye worm) | hypothetical protein | 0.0955 | 0.6599 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0955 | 0.6599 | 1 |
Loa Loa (eye worm) | TYRA-2 protein | 0.0955 | 0.6599 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0955 | 0.6599 | 1 |
Schistosoma mansoni | peptide (allatostatin)-like receptor | 0.0955 | 0.6599 | 0.6599 |
Loa Loa (eye worm) | hypothetical protein | 0.0955 | 0.6599 | 1 |
Loa Loa (eye worm) | G-protein coupled receptor | 0.0955 | 0.6599 | 1 |
Trypanosoma cruzi | ribonucleoside-diphosphate reductase large chain, putative | 0.0136 | 0.0084 | 0.5 |
Echinococcus multilocularis | epidermal growth factor receptor | 0.0366 | 0.1913 | 0.2115 |
Loa Loa (eye worm) | hypothetical protein | 0.0217 | 0.0725 | 0.1099 |
Brugia malayi | Nuclear hormone receptor-like 1 | 0.0217 | 0.0725 | 0.0984 |
Schistosoma mansoni | hypothetical protein | 0.0955 | 0.6599 | 0.6599 |
Loa Loa (eye worm) | hypothetical protein | 0.0159 | 0.0266 | 0.0403 |
Schistosoma mansoni | steroid hormone receptor ad4bp | 0.0217 | 0.0725 | 0.0725 |
Loa Loa (eye worm) | hypothetical protein | 0.0955 | 0.6599 | 1 |
Echinococcus multilocularis | tachykinin peptides receptor 99D | 0.0955 | 0.6599 | 0.7534 |
Loa Loa (eye worm) | hypothetical protein | 0.0955 | 0.6599 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0955 | 0.6599 | 1 |
Echinococcus multilocularis | sex peptide receptor | 0.0955 | 0.6599 | 0.7534 |
Schistosoma mansoni | neuropeptide receptor | 0.0955 | 0.6599 | 0.6599 |
Echinococcus granulosus | neuropeptide Y receptor | 0.0955 | 0.6599 | 0.6599 |
Loa Loa (eye worm) | hypothetical protein | 0.0955 | 0.6599 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0955 | 0.6599 | 1 |
Loa Loa (eye worm) | ribonucleoside-diphosphate reductase large subunit | 0.0136 | 0.0084 | 0.0127 |
Brugia malayi | Nuclear hormone receptor family member nhr-3 | 0.0217 | 0.0725 | 0.0984 |
Loa Loa (eye worm) | hypothetical protein | 0.0955 | 0.6599 | 1 |
Loa Loa (eye worm) | TK/INSR protein kinase | 0.0221 | 0.0761 | 0.1153 |
Loa Loa (eye worm) | hypothetical protein | 0.0955 | 0.6599 | 1 |
Echinococcus granulosus | nuclear receptor 2DBD gamma | 0.0217 | 0.0725 | 0.0725 |
Schistosoma mansoni | adenoreceptor | 0.0955 | 0.6599 | 0.6599 |
Brugia malayi | Nuclear hormone receptor family member nhr-19 | 0.0217 | 0.0725 | 0.0984 |
Plasmodium vivax | ribonucleoside-diphosphate reductase large chain, putative | 0.0136 | 0.0084 | 0.5 |
Loa Loa (eye worm) | hypothetical protein | 0.0955 | 0.6599 | 1 |
Echinococcus granulosus | tachykinin peptides receptor 99D | 0.0955 | 0.6599 | 0.6599 |
Brugia malayi | Ligand-binding domain of nuclear hormone receptor family protein | 0.0217 | 0.0725 | 0.0984 |
Onchocerca volvulus | 0.0955 | 0.6599 | 1 | |
Loa Loa (eye worm) | hypothetical protein | 0.0955 | 0.6599 | 1 |
Loa Loa (eye worm) | nuclear hormone receptor-like 1 | 0.0159 | 0.0266 | 0.0403 |
Echinococcus multilocularis | thyroid hormone receptor alpha | 0.0217 | 0.0725 | 0.0742 |
Schistosoma mansoni | retinoid-x-receptor (RXR) | 0.0217 | 0.0725 | 0.0725 |
Echinococcus granulosus | ecdysone induced protein 78C | 0.0217 | 0.0725 | 0.0725 |
Echinococcus granulosus | Nuclear hormone receptor family member nhr 41 | 0.0217 | 0.0725 | 0.0725 |
Brugia malayi | sulfakinin receptor protein | 0.0955 | 0.6599 | 1 |
Echinococcus granulosus | neuropeptides capa receptor | 0.0955 | 0.6599 | 0.6599 |
Schistosoma mansoni | neuropeptide receptor | 0.0955 | 0.6599 | 0.6599 |
Echinococcus multilocularis | alpha 1A adrenergic receptor | 0.0955 | 0.6599 | 0.7534 |
Loa Loa (eye worm) | hypothetical protein | 0.0955 | 0.6599 | 1 |
Brugia malayi | G protein-coupled receptor F59B2.13 | 0.0955 | 0.6599 | 1 |
Brugia malayi | Dopamine receptor | 0.0955 | 0.6599 | 1 |
Echinococcus granulosus | g protein coupled receptor | 0.0955 | 0.6599 | 0.6599 |
Loa Loa (eye worm) | 5-hydroxytryptamine 2C receptor | 0.0955 | 0.6599 | 1 |
Brugia malayi | Nuclear hormone receptor family member nhr-31 | 0.0217 | 0.0725 | 0.0984 |
Echinococcus granulosus | G protein coupled receptor 139 | 0.0955 | 0.6599 | 0.6599 |
Brugia malayi | follicle stimulating hormone receptor | 0.0955 | 0.6599 | 1 |
Echinococcus multilocularis | insulin receptor | 0.0221 | 0.0761 | 0.0782 |
Schistosoma mansoni | thyroid hormone receptor | 0.0217 | 0.0725 | 0.0725 |
Schistosoma mansoni | biogenic amine (dopamine) receptor | 0.0955 | 0.6599 | 0.6599 |
Loa Loa (eye worm) | hypothetical protein | 0.0217 | 0.0725 | 0.1099 |
Loa Loa (eye worm) | hypothetical protein | 0.0955 | 0.6599 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0955 | 0.6599 | 1 |
Onchocerca volvulus | 0.0955 | 0.6599 | 1 | |
Echinococcus granulosus | G protein coupled 5 hydroxytryptamine receptor | 0.0955 | 0.6599 | 0.6599 |
Schistosoma mansoni | hypothetical protein | 0.0955 | 0.6599 | 0.6599 |
Echinococcus granulosus | hypothetical protein | 0.0955 | 0.6599 | 0.6599 |
Echinococcus multilocularis | rhodopsin orphan GPCR | 0.0955 | 0.6599 | 0.7534 |
Activity type | Activity value | Assay description | Source | Reference |
---|---|---|---|---|
IC50 (binding) | = 42 uM | Inhibitory activity was determined against HSV-1 Ribonucleoside diphosphate reductase | ChEMBL. | 2153825 |
IC50 (binding) | = 60 uM | Inhibitory activity against HSV-1 Ribonucleoside diphosphate reductase was determined | ChEMBL. | 2153825 |
Relative inhibition (binding) | = 183 % | Relative inhibition of Ribonucleoside diphosphate reductase by the compound compared to HSV-R2-(329-337) | ChEMBL. | 2153825 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.
1 literature reference was collected for this gene.