Detailed information for compound 408306

Basic information

Technical information
  • Name: Unnamed compound
  • MW: 2245.74 | Formula: C104H169N35O19S
  • H donors: 32 H acceptors: 19 LogP: -4.12 Rotable bonds: 98
    Rule of 5 violations (Lipinski): 4
  • SMILES: NCCCC[C@@H](C(=O)N[C@H](C(=O)N[C@H](C(=O)N[C@H](C(=O)N[C@H](C(=O)N[C@H](C(=O)N[C@H](C(=O)N[C@H](C(=O)N[C@H](C(=O)N[C@H](C(=O)N[C@H](C(=O)N[C@H](C(=O)N[C@H](C(=O)N)CCCCN)CCCCN)Cc1c[nH]c2c1cccc2)CCCCN)CCSC)CCCNC(=N)N)CCCNC(=N)N)CC(=O)N)CCC(=O)N)Cc1ccccc1)Cc1c[nH]c2c1cccc2)[C@H](CC)C)NC(=O)[C@H]([C@H](CC)C)NC(=O)[C@@H](NC(=O)[C@H](CCCNC(=N)N)N)CCC(=O)N
  • InChi: 1S/C104H169N35O19S/c1-6-58(3)84(139-95(152)75(40-42-82(111)141)126-87(144)65(109)30-23-48-120-102(114)115)100(157)133-71(36-18-22-47-108)94(151)138-85(59(4)7-2)101(158)137-79(54-62-57-124-67-32-14-12-29-64(62)67)98(155)134-77(52-60-26-9-8-10-27-60)96(153)131-74(39-41-81(110)140)92(149)136-80(55-83(112)142)99(156)130-73(38-25-50-122-104(118)119)89(146)128-72(37-24-49-121-103(116)117)90(147)132-76(43-51-159-5)93(150)127-70(35-17-21-46-107)91(148)135-78(53-61-56-123-66-31-13-11-28-63(61)66)97(154)129-69(34-16-20-45-106)88(145)125-68(86(113)143)33-15-19-44-105/h8-14,26-29,31-32,56-59,65,68-80,84-85,123-124H,6-7,15-25,30,33-55,105-109H2,1-5H3,(H2,110,140)(H2,111,141)(H2,112,142)(H2,113,143)(H,125,145)(H,126,144)(H,127,150)(H,128,146)(H,129,154)(H,130,156)(H,131,153)(H,132,147)(H,133,157)(H,134,155)(H,135,148)(H,136,149)(H,137,158)(H,138,151)(H,139,152)(H4,114,115,120)(H4,116,117,121)(H4,118,119,122)/t58-,59-,65-,68-,69-,70-,71-,72-,73-,74-,75-,76-,77-,78-,79-,80-,84-,85-/m0/s1
  • InChiKey: MCYTYTUNNNZWOK-LCLOTLQISA-N  


Substructure search Similarity search

Network

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Synonyms

No synonyms found for this compound

Targets

Known targets for this compound

No curated genes were found associated with this compound

Predicted pathogen targets for this compound

By orthology
No druggable targets predicted by orthology data
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Loa Loa (eye worm) hypothetical protein 0.1097 0.6766 1
Plasmodium falciparum serine repeat antigen 2 0.0033 0.0131 0.1195
Trypanosoma cruzi Protein prenyltransferase alpha subunit repeat, putative 0.0049 0.0229 0.0274
Onchocerca volvulus 0.0242 0.1436 0.382
Toxoplasma gondii cathepsin B 0.0362 0.2183 1
Brugia malayi Calcitonin receptor-like protein seb-1 0.0051 0.0243 0.0359
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0045 0.0205 0.0297
Toxoplasma gondii centrin 0.0045 0.0205 0.0937
Trichomonas vaginalis centrin, putative 0.0045 0.0205 0.0785
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0016 0.0027 0.0033
Brugia malayi GnHR receptor homolog 0.0016 0.0027 0.0039
Giardia lamblia Dipeptidyl-peptidase I precursor 0.0033 0.0131 0.0401
Giardia lamblia Rab geranylgeranyltransferase 0.0049 0.0229 0.0861
Trypanosoma cruzi I/6 autoantigen, putative 0.0045 0.0205 0.0237
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.0033 0.0131 0.0188
Leishmania major cysteine peptidase C (CPC),CPC cysteine peptidase, Clan CA, family C1, Cathepsin B-like 0.0362 0.2183 0.9937
Trypanosoma cruzi calmodulin, putative 0.0045 0.0205 0.0237
Echinococcus granulosus calcium uptake protein 1 0.0045 0.0205 0.0297
Entamoeba histolytica acyl-CoA synthetase, putative 0.0026 0.009 0.0295
Loa Loa (eye worm) papain family cysteine protease containing protein 0.0033 0.0131 0.0194
Trypanosoma cruzi protein farnesyltransferase alpha subunit, putative 0.0049 0.0229 0.0274
Schistosoma mansoni tar DNA-binding protein 0.0134 0.0764 0.1123
Schistosoma mansoni neuropeptide receptor 0.0016 0.0027 0.0033
Schistosoma mansoni ancient conserved domain protein 2 (cyclin m2) 0.0016 0.0027 0.0033
Trypanosoma cruzi calpain-like cysteine peptidase, putative 0.0104 0.0572 0.0784
Loa Loa (eye worm) hypothetical protein 0.0016 0.0027 0.0039
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD5 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0019 0.0042 0.0251
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.1097 0.6766 1
Trypanosoma cruzi FHA domain containing protein, putative 0.0021 0.0057 0.0017
Brugia malayi calpain 5 0.0261 0.155 0.2291
Echinococcus granulosus rhodopsin orphan GPCR 0.0016 0.0027 0.0033
Treponema pallidum exodeoxyribonuclease (exoA) 0.0019 0.0045 0.0418
Schistosoma mansoni hypothetical protein 0.0016 0.0026 0.0033
Leishmania major calmodulin-like protein 0.0045 0.0205 0.074
Echinococcus granulosus cathepsin b 0.1097 0.6766 1
Echinococcus granulosus peptide allatostatin:somatostatin 0.0016 0.0027 0.0033
Leishmania major cathepsin L-like protease 0.0033 0.0131 0.0398
Echinococcus multilocularis orexin receptor type 2 0.0016 0.0027 0.0023
Echinococcus multilocularis alpha 1A adrenergic receptor 0.0016 0.0027 0.0023
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0033 0.0131 0.0442
Schistosoma mansoni amine GPCR 0.0016 0.0027 0.0033
Echinococcus granulosus neuropeptides capa receptor 0.0016 0.0027 0.0033
Schistosoma mansoni hypothetical protein 0.0035 0.0143 0.0205
Loa Loa (eye worm) hypothetical protein 0.0036 0.0147 0.0218
Onchocerca volvulus Cathepsin L homolog 0.0033 0.0131 0.0348
Mycobacterium leprae PROBABLE FATTY-ACID-CoA LIGASE FADD7 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) 0.0026 0.009 1
Loa Loa (eye worm) hypothetical protein 0.0033 0.0131 0.0194
Echinococcus multilocularis pyroglutamylated rfamide peptide receptor 0.0016 0.0027 0.0023
Plasmodium falciparum replication factor C subunit 1, putative 0.0021 0.0057 0.0519
Brugia malayi eukaryotic initiation factor 4A 0.0053 0.0257 0.038
Loa Loa (eye worm) hypothetical protein 0.0016 0.0027 0.0039
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.0033 0.0131 0.0188
Trypanosoma cruzi I/6 autoantigen, putative 0.0045 0.0205 0.0237
Trypanosoma brucei protein farnesyltransferase beta subunit 0.0131 0.0743 0.3241
Entamoeba histolytica cysteine protease, putative 0.0033 0.0131 0.0569
Echinococcus multilocularis geranylgeranyl transferase type 2 subunit alpha 0.0049 0.0229 0.0225
Trichomonas vaginalis calcium binding protein, putative 0.0048 0.0227 0.089
Plasmodium vivax dipeptidyl aminopeptidase 2, putative 0.0033 0.0131 0.0597
Loa Loa (eye worm) unidentified vitellogenin-linked transcript protein 6 0.0016 0.0027 0.0039
Schistosoma mansoni rab geranylgeranyl transferase alpha subunit 0.0049 0.0229 0.0333
Schistosoma mansoni calpain C (C02 family) 0.0364 0.2197 0.3243
Echinococcus granulosus g protein linked acetylcholine receptor gar 2a 0.0016 0.0027 0.0033
Schistosoma mansoni hypothetical protein 0.0454 0.2756 0.4069
Onchocerca volvulus 0.0016 0.0027 0.0071
Plasmodium vivax vivapain-1 0.0033 0.0131 0.0597
Loa Loa (eye worm) hypothetical protein 0.0016 0.0027 0.0039
Loa Loa (eye worm) hypothetical protein 0.0021 0.0057 0.0084
Leishmania major kinesin, putative 0.0261 0.155 0.6994
Schistosoma mansoni neuropeptide f receptor 76f 0.0016 0.0027 0.0033
Schistosoma mansoni hypothetical protein 0.0016 0.0026 0.0033
Mycobacterium ulcerans long-chain fatty-acid CoA ligase 0.0026 0.009 1
Loa Loa (eye worm) Papain cysteine protease/cathepsin propeptide inhibitor-containing protein 0.0033 0.0131 0.0194
Plasmodium vivax serine-repeat antigen (SERA), putative 0.0033 0.0131 0.0597
Trichomonas vaginalis geranylgeranyl transferase type II beta subunit, putative 0.0131 0.0743 0.329
Trypanosoma brucei Calpain-like protein 2 0.0104 0.0572 0.245
Schistosoma mansoni alpha-1 adrenergic receptor 0.0016 0.0027 0.0033
Loa Loa (eye worm) hypothetical protein 0.0016 0.0027 0.0039
Leishmania major cathepsin L-like protease 0.0033 0.0131 0.0398
Toxoplasma gondii troponin c, isotype gamma, putative 0.0045 0.0205 0.0937
Echinococcus multilocularis cathepsin L cysteine protease 0.0033 0.0131 0.0127
Schistosoma mansoni calmodulin 0.0045 0.0205 0.0297
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.0364 0.2197 1
Trichomonas vaginalis RNA polymerase II ctd phosphatase, putative 0.0021 0.0057 0.0097
Trypanosoma cruzi centrin, putative 0.0048 0.0227 0.027
Trypanosoma cruzi cysteine peptidase, Clan CA, family C2, putative 0.0104 0.0572 0.0784
Leishmania major calpain protease-like protein 0.0104 0.0572 0.245
Entamoeba histolytica cysteine proteinase, putative 0.0033 0.0131 0.0569
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD2 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0026 0.009 0.2431
Schistosoma mansoni ap endonuclease 0.0019 0.0045 0.0061
Brugia malayi CHE-14 protein 0.0084 0.0451 0.0666
Echinococcus multilocularis cathepsin l cysteine peptidase 0.0033 0.0131 0.0127
Loa Loa (eye worm) hypothetical protein 0.0031 0.012 0.0177
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.0104 0.0572 0.245
Loa Loa (eye worm) hypothetical protein 0.0016 0.0027 0.0039
Giardia lamblia Cathepsin L-like protease 0.0033 0.0131 0.0401
Echinococcus multilocularis EF HAND 1, calcium binding site 0.0045 0.0205 0.0201
Loa Loa (eye worm) hypothetical protein 0.002 0.0048 0.0072
Echinococcus granulosus rhodopsin orphan GPCR 0.0016 0.0027 0.0033
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.0033 0.0131 0.0188
Echinococcus granulosus rhodopsin orphan GPCR 0.0016 0.0027 0.0033
Trypanosoma cruzi lanosterol synthase, putative 0.0036 0.0147 0.0152
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.0033 0.0131 0.0188
Echinococcus granulosus rhodopsin orphan GPCR 0.0016 0.0027 0.0033
Loa Loa (eye worm) hypothetical protein 0.0016 0.0026 0.0039
Trichomonas vaginalis conserved hypothetical protein 0.0021 0.0057 0.0097
Echinococcus granulosus g protein coupled receptor 0.0016 0.0027 0.0033
Schistosoma mansoni hypothetical protein 0.0016 0.0027 0.0033
Brugia malayi hypothetical protein 0.0016 0.0027 0.0039
Onchocerca volvulus 0.0045 0.0205 0.0544
Echinococcus multilocularis allatostatin A receptor 0.0016 0.0027 0.0023
Echinococcus multilocularis cathepsin L 0.0033 0.0131 0.0127
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0033 0.0131 0.0398
Loa Loa (eye worm) hypothetical protein 0.0033 0.0131 0.0194
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0033 0.0131 0.0398
Schistosoma mansoni histone-lysine n-methyltransferase suv9 0.0031 0.012 0.0171
Entamoeba histolytica geranylgeranyl transferase beta subunit 0.0036 0.0147 0.0678
Plasmodium falciparum cysteine proteinase falcipain 2a 0.0033 0.0131 0.1195
Trypanosoma cruzi hypothetical protein, conserved 0.0021 0.0057 0.0017
Entamoeba histolytica protein farnesyltransferase beta subunit, putative 0.0131 0.0743 0.4633
Entamoeba histolytica EF-hand calcium-binding domain containing protein 0.0045 0.0205 0.1058
Loa Loa (eye worm) RNA recognition domain-containing protein domain-containing protein 0.0134 0.0764 0.1129
Echinococcus multilocularis rhodopsin orphan GPCR 0.0016 0.0027 0.0023
Loa Loa (eye worm) hypothetical protein 0.0016 0.0027 0.0039
Echinococcus multilocularis tar DNA binding protein 0.0134 0.0764 0.076
Echinococcus multilocularis calbindin 32 0.0045 0.0205 0.0201
Entamoeba histolytica cysteine proteinase, putative 0.0033 0.0131 0.0569
Schistosoma mansoni thyrotropin-releasing hormone receptor 0.0016 0.0027 0.0033
Echinococcus multilocularis expressed conserved protein 0.0184 0.1075 0.1071
Echinococcus granulosus calumenin 0.0045 0.0205 0.0297
Entamoeba histolytica cysteine protease, putative 0.0033 0.0131 0.0569
Echinococcus multilocularis survival motor neuron protein 1 0.0471 0.2864 0.2861
Loa Loa (eye worm) hypothetical protein 0.0152 0.0876 0.1294
Echinococcus multilocularis rhodopsin orphan GPCR 0.0016 0.0027 0.0023
Entamoeba histolytica hypothetical protein 0.0021 0.0057 0.0077
Echinococcus granulosus sarcoplasmic calcium binding protein 0.0045 0.0205 0.0297
Giardia lamblia Cathepsin B precursor 0.0033 0.0131 0.0401
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0045 0.0205 0.0297
Loa Loa (eye worm) hypothetical protein 0.0026 0.009 0.0133
Loa Loa (eye worm) calpain 5 0.0261 0.155 0.2291
Loa Loa (eye worm) hypothetical protein 0.0021 0.0057 0.0084
Giardia lamblia Cathepsin B precursor 0.0033 0.0131 0.0401
Echinococcus granulosus calpain 5 0.0364 0.2197 0.3243
Loa Loa (eye worm) hypothetical protein 0.0026 0.009 0.0133
Brugia malayi ATP dependent DNA ligase C terminal region family protein 0.0021 0.0057 0.0084
Echinococcus multilocularis Basic leucine zipper (bZIP) transcription 0.0113 0.0632 0.0628
Schistosoma mansoni subfamily C1A non-peptidase homologue (C01 family) 0.0033 0.0131 0.0188
Schistosoma mansoni aminoadipate-semialdehyde dehydrogenase 0.0085 0.0454 0.0666
Trypanosoma cruzi hypothetical protein, conserved 0.0021 0.0057 0.0017
Echinococcus granulosus neuropeptide Y receptor 0.0016 0.0027 0.0033
Trypanosoma brucei Protein prenyltransferase alpha subunit repeat, putative 0.0049 0.0229 0.0855
Echinococcus granulosus neurocalcin 0.0045 0.0205 0.0297
Schistosoma mansoni cpg binding protein 0.0034 0.0136 0.0195
Trypanosoma cruzi protein farnesyltransferase alpha subunit, putative 0.0049 0.0229 0.0274
Leishmania major phosphopantetheinyl transferase-like protein 0.0024 0.0075 0.0135
Brugia malayi DKFZp564C0469 protein 0.0021 0.0057 0.0084
Schistosoma mansoni hypothetical protein 0.0016 0.0026 0.0033
Giardia lamblia Cathepsin L precursor 0.0033 0.0131 0.0401
Toxoplasma gondii poly(ADP-ribose) polymerase catalytic domain-containing protein 0.0021 0.0057 0.0261
Loa Loa (eye worm) hypothetical protein 0.0048 0.0224 0.0331
Loa Loa (eye worm) TYRA-2 protein 0.0016 0.0027 0.0039
Trichomonas vaginalis protein farnesyltransferase beta subunit, putative 0.0036 0.0147 0.0518
Loa Loa (eye worm) ctsf protein 0.0033 0.0131 0.0194
Loa Loa (eye worm) neuropeptide F receptor 0.0016 0.0027 0.0039
Mycobacterium ulcerans exodeoxyribonuclease III protein XthA 0.0019 0.0045 0.1722
Trypanosoma cruzi lanosterol synthase, putative 0.0036 0.0147 0.0152
Trypanosoma brucei calpain-like protein, putative 0.0364 0.2197 1
Toxoplasma gondii 4'-phosphopantetheinyl transferase superfamily protein 0.0024 0.0075 0.0341
Schistosoma mansoni apoferritin-2 0.0018 0.0036 0.0047
Schistosoma mansoni hypothetical protein 0.0016 0.0027 0.0033
Echinococcus multilocularis histone lysine N methyltransferase SETMAR 0.0031 0.012 0.0116
Loa Loa (eye worm) hypothetical protein 0.011 0.0609 0.09
Trypanosoma cruzi cysteine peptidase (N-terminal), putative 0.0033 0.0131 0.0127
Giardia lamblia Cysteine protease 0.0033 0.0131 0.0401
Schistosoma mansoni hypothetical protein 0.0113 0.0632 0.0929
Schistosoma mansoni calpain-7 (C02 family) 0.0364 0.2197 0.3243
Trichomonas vaginalis geranylgeranyl transferase type beta subunit, putative 0.0131 0.0743 0.329
Echinococcus multilocularis serotonin receptor 0.0016 0.0027 0.0023
Brugia malayi hypothetical protein 0.0016 0.0027 0.0039
Trichomonas vaginalis geranylgeranyl transferase type I beta subunit, putative 0.0131 0.0743 0.329
Brugia malayi RNA binding protein 0.0134 0.0764 0.1129
Schistosoma mansoni tar DNA-binding protein 0.0134 0.0764 0.1123
Loa Loa (eye worm) hypothetical protein 0.0016 0.0027 0.0039
Echinococcus multilocularis GPCR, family 2 0.0016 0.0026 0.0022
Schistosoma mansoni ap endonuclease 0.0019 0.0045 0.0061
Onchocerca volvulus Neuropeptide F receptor homolog 0.0016 0.0027 0.0071
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0045 0.0205 0.0201
Loa Loa (eye worm) hypothetical protein 0.0016 0.0027 0.0039
Plasmodium vivax serine-repeat antigen (SERA), putative 0.0033 0.0131 0.0597
Giardia lamblia Rab geranylgeranyltransferase 0.0036 0.0147 0.0477
Brugia malayi Cathepsin L-like precursor 0.0033 0.0131 0.0194
Schistosoma mansoni neuropeptide receptor 0.0016 0.0027 0.0033
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0033 0.0131 0.0442
Mycobacterium tuberculosis Probable chain -fatty-acid-CoA ligase FadD13 (fatty-acyl-CoA synthetase) 0.0026 0.009 0.2431
Schistosoma mansoni calpain-2 (C02 family) 0.0104 0.0572 0.0841
Brugia malayi exodeoxyribonuclease III family protein 0.0019 0.0045 0.0067
Trypanosoma cruzi centrin, putative 0.0048 0.0227 0.027
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0016 0.0027 0.0033
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0033 0.0131 0.0442
Brugia malayi Papain family cysteine protease containing protein 0.0033 0.0131 0.0194
Brugia malayi calpain 5 0.0104 0.0572 0.0846
Schistosoma mansoni neuronal calcium sensor 0.0045 0.0205 0.0297
Trypanosoma cruzi hypothetical protein, conserved 0.0036 0.0147 0.0152
Trichomonas vaginalis Clan CA, family C1, cathepsin H-like cysteine peptidase 0.0033 0.0131 0.0442
Trypanosoma brucei protein farnesyltransferase alpha subunit, putative 0.0049 0.0229 0.0855
Echinococcus granulosus neuropeptide s receptor 0.0976 0.6014 0.8887
Loa Loa (eye worm) hypothetical protein 0.0016 0.0027 0.0039
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0033 0.0131 0.0442
Echinococcus granulosus cathepsin l cysteine peptidase 0.0033 0.0131 0.0188
Echinococcus granulosus neuropeptides capa receptor 0.0016 0.0027 0.0033
Leishmania major hypothetical protein, conserved 0.0045 0.0205 0.074
Trichomonas vaginalis Clan CA, family C1, cathepsin B-like cysteine peptidase 0.0033 0.0131 0.0442
Loa Loa (eye worm) hypothetical protein 0.0016 0.0027 0.0039
Giardia lamblia Encystation-specific protease 0.0033 0.0131 0.0401
Plasmodium falciparum dipeptidyl aminopeptidase 1 0.0033 0.0131 0.1195
Onchocerca volvulus 0.0031 0.012 0.0319
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.0104 0.0572 0.245
Leishmania major phospholipase c-like protein 0.0045 0.0205 0.074
Echinococcus granulosus g protein coupled receptor 0.0016 0.0027 0.0033
Schistosoma mansoni transcription factor LCR-F1 0.0113 0.0632 0.0929
Trypanosoma brucei cysteine peptidase, Clan CA, family C2, putative 0.0104 0.0572 0.245
Entamoeba histolytica EF-hand calcium-binding domain containing protein 0.0045 0.0205 0.1058
Plasmodium vivax acyl-CoA synthetase, putative 0.002 0.0048 0.022
Loa Loa (eye worm) hypothetical protein 0.0021 0.0057 0.0084
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0033 0.0131 0.0442
Entamoeba histolytica cysteine protease, putative 0.0033 0.0131 0.0569
Echinococcus granulosus cadherin EGF LAG seven pass G type receptor 0.0016 0.0026 0.0033
Schistosoma mansoni biogenic amine receptor 0.0016 0.0027 0.0033
Schistosoma mansoni tar DNA-binding protein 0.0134 0.0764 0.1123
Trichomonas vaginalis Clan CA, family C1, cathepsin B-like cysteine peptidase 0.0033 0.0131 0.0442
Schistosoma mansoni adenoreceptor 0.0016 0.0027 0.0033
Echinococcus granulosus GPCR family 2 0.0016 0.0026 0.0033
Schistosoma mansoni subfamily C1A unassigned peptidase (C01 family) 0.0033 0.0131 0.0188
Trypanosoma cruzi calpain cysteine peptidase, putative 0.0104 0.0572 0.0784
Brugia malayi calpain 7 0.0364 0.2197 0.3247
Brugia malayi GTP-binding regulatory protein Gs alpha-S chain, putative 0.0045 0.0205 0.0302
Echinococcus multilocularis DNA (apurinic or apyrimidinic site) lyase 0.0019 0.0045 0.0041
Plasmodium vivax serine-repeat antigen 4 (SERA) 0.0033 0.0131 0.0597
Onchocerca volvulus Eukaryotic initiation factor 4A homolog 0.0053 0.0257 0.0684
Leishmania major calmodulin, putative 0.0045 0.0205 0.074
Schistosoma mansoni ferritin 0.0018 0.0036 0.0047
Onchocerca volvulus 0.0016 0.0027 0.0071
Mycobacterium tuberculosis Fatty-acid-AMP ligase FadD30 (fatty-acid-AMP synthetase) (fatty-acid-AMP synthase) 0.002 0.0048 0.0554
Schistosoma mansoni peptide (FMRFamide/neurokinin-3)-like receptor 0.0016 0.0027 0.0033
Brugia malayi hypothetical protein 0.0028 0.01 0.0148
Trypanosoma cruzi cysteine peptidase, putative 0.0033 0.0131 0.0127
Schistosoma mansoni histamine h1 receptor 0.0016 0.0027 0.0033
Schistosoma mansoni DNA ligase IV 0.0021 0.0057 0.0078
Trypanosoma brucei calpain, putative 0.0104 0.0572 0.245
Trypanosoma cruzi Present in the outer mitochondrial membrane proteome 33 0.0045 0.0205 0.0237
Plasmodium falciparum serine repeat antigen 5 0.0033 0.0131 0.1195
Echinococcus multilocularis neuronal calcium sensor 0.0045 0.0205 0.0201
Trypanosoma brucei Component of motile flagella 41 0.0045 0.0205 0.074
Echinococcus multilocularis calpain family protein 1, d 0.0719 0.4407 0.4405
Loa Loa (eye worm) hypothetical protein 0.0033 0.0131 0.0194
Schistosoma mansoni Sarcoplasmic calcium-binding protein (SCP). 0.0045 0.0205 0.0297
Trypanosoma brucei calpain-like protein, putative 0.0364 0.2197 1
Echinococcus granulosus neuropeptide receptor A26 0.0976 0.6014 0.8887
Trypanosoma brucei cysteine peptidase, putative 0.0104 0.0572 0.245
Brugia malayi RNA recognition motif domain containing protein 0.0134 0.0764 0.1129
Brugia malayi Protein prenyltransferase alpha subunit repeat containing protein 0.0188 0.1097 0.1621
Schistosoma mansoni family C2 unassigned peptidase (C02 family) 0.1024 0.631 0.9325
Onchocerca volvulus 0.0016 0.0027 0.0071
Brugia malayi larval opioid receptor 0.0016 0.0027 0.0039
Trichomonas vaginalis set domain proteins, putative 0.0242 0.1436 0.6521
Trichomonas vaginalis calmodulin, putative 0.0045 0.0205 0.0785
Toxoplasma gondii histone lysine methyltransferase SET/SUV39 0.0031 0.012 0.055
Echinococcus granulosus serotonin receptor 0.0016 0.0027 0.0033
Schistosoma mansoni family C2 unassigned peptidase (C02 family) 0.0979 0.6031 0.8913
Onchocerca volvulus 0.0016 0.0027 0.0071
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.0104 0.0572 0.245
Echinococcus granulosus cathepsin L 0.0033 0.0131 0.0188
Onchocerca volvulus 0.0016 0.0027 0.0071
Leishmania major geranylgeranyltransferase, putative 0.0036 0.0147 0.0474
Leishmania major cathepsin L-like protease 0.0033 0.0131 0.0398
Plasmodium vivax conserved Plasmodium protein, unknown function 0.0095 0.0521 0.2372
Leishmania major centrin, putative 0.0045 0.0205 0.074
Giardia lamblia Prenyltransferase 0.0131 0.0743 0.3261
Toxoplasma gondii hypothetical protein 0.0049 0.0229 0.1051
Schistosoma mansoni cathepsin F (C01 family) 0.0033 0.0131 0.0188
Echinococcus granulosus protein farnesyltransferase alpha subunit 0.0188 0.1097 0.1616
Onchocerca volvulus 0.0048 0.0224 0.0595
Echinococcus multilocularis Rab geranylgeranyltransferase, beta subunit 0.0036 0.0147 0.0143
Mycobacterium ulcerans NAD-dependent DNA ligase LigA 0.0021 0.0057 0.3872
Mycobacterium ulcerans 4'-phosphopantetheinyl transferase 0.0024 0.0075 0.7141
Loa Loa (eye worm) hypothetical protein 0.0016 0.0027 0.0039
Echinococcus multilocularis g protein linked acetylcholine receptor gar 2a 0.0016 0.0027 0.0023
Toxoplasma gondii prenyltransferase and squalene oxidase repeat-containing protein 0.0131 0.0743 0.3401
Echinococcus granulosus survival motor neuron protein 1 0.0471 0.2864 0.4229
Echinococcus granulosus EF hand domain containing family member A2 0.0045 0.0205 0.0297
Plasmodium falciparum serine repeat antigen 8 0.0033 0.0131 0.1195
Brugia malayi Cathepsin L-like precursor 0.0033 0.0131 0.0194
Echinococcus multilocularis cadherin EGF LAG seven pass G type receptor 0.0016 0.0026 0.0022
Loa Loa (eye worm) cysteine protease 0.0033 0.0131 0.0194
Onchocerca volvulus 0.0033 0.0131 0.0348
Trichomonas vaginalis RNA polymerase II ctd phosphatase, putative 0.0021 0.0057 0.0097
Trypanosoma cruzi calpain-like cysteine peptidase, putative 0.0104 0.0572 0.0784
Schistosoma mansoni reticulocalbin 0.0045 0.0205 0.0297
Leishmania major cytoskeleton-associated protein CAP5.5, putative,cysteine peptidase, Clan CA, family C2, putative 0.0104 0.0572 0.245
Schistosoma mansoni neuropeptide F-like receptor 0.0016 0.0027 0.0033
Schistosoma mansoni niemann-pick C1 (NPC1) 0.0199 0.1168 0.1721
Toxoplasma gondii prenyltransferase and squalene oxidase repeat-containing protein 0.0036 0.0147 0.0675
Plasmodium vivax ataxin-2 like protein, putative 0.0028 0.01 0.0456
Echinococcus granulosus rhodopsin orphan GPCR 0.0016 0.0027 0.0033
Trypanosoma brucei protein I/6 0.0045 0.0205 0.074
Echinococcus granulosus protein farnesyltransferase subunit beta 0.0131 0.0743 0.1092
Brugia malayi calpain D 0.0104 0.0572 0.0846
Trypanosoma brucei Calpain-like protein 1.1 0.0104 0.0572 0.245
Echinococcus granulosus cathepsin L cysteine proteinase 0.0033 0.0131 0.0188
Loa Loa (eye worm) cathepsin B 0.0362 0.2183 0.3227
Treponema pallidum ATP-dependent RNA helicase 0.0053 0.0257 1
Echinococcus granulosus diuretic hormone 44 receptor GPRdih2 0.0016 0.0026 0.0033
Echinococcus multilocularis nibrin 0.0021 0.0057 0.0053
Toxoplasma gondii exonuclease III APE 0.0019 0.0045 0.0208
Schistosoma mansoni hypothetical protein 0.0096 0.0525 0.077
Brugia malayi Serotonin/octopamine receptor family protein 7 0.0016 0.0027 0.0039
Leishmania major calmodulin, putative 0.0045 0.0205 0.074
Echinococcus multilocularis family C2 unassigned peptidase (C02 family) 0.1024 0.631 0.6309
Schistosoma mansoni calcium binding atopy-related autoantigen 0.0045 0.0205 0.0297
Schistosoma mansoni myosin xvIII 0.0016 0.0027 0.0033
Giardia lamblia Dipeptidyl-peptidase I precursor 0.0033 0.0131 0.0401
Trichomonas vaginalis calpain, putative 0.0104 0.0572 0.2498
Loa Loa (eye worm) hypothetical protein 0.0979 0.6031 0.8914
Plasmodium falciparum geranylgeranyl transferase type-2 subunit alpha, putative 0.0049 0.0229 0.2092
Schistosoma mansoni Mername-AA248 (C02 family) 0.0364 0.2197 0.3243
Loa Loa (eye worm) hypothetical protein 0.0053 0.0257 0.038
Loa Loa (eye worm) prenyltransferase alpha subunit repeat containing protein 0.0049 0.0229 0.0339
Trichomonas vaginalis calmodulin, putative 0.0045 0.0205 0.0785
Loa Loa (eye worm) CXXC zinc finger family protein 0.0032 0.0125 0.0184
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0033 0.0131 0.0442
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.0364 0.2197 1
Echinococcus granulosus family C2 unassigned peptidase C02 family 0.1024 0.631 0.9325
Loa Loa (eye worm) hypothetical protein 0.0016 0.0027 0.0039
Entamoeba histolytica cysteine protease, putative 0.0033 0.0131 0.0569
Echinococcus multilocularis tachykinin peptides receptor 99D 0.0016 0.0027 0.0023
Schistosoma mansoni hypothetical protein 0.0016 0.0026 0.0033
Loa Loa (eye worm) hypothetical protein 0.0016 0.0027 0.0039
Trichomonas vaginalis Clan CA, family C1, cathepsin B-like cysteine peptidase 0.0362 0.2183 1
Brugia malayi AMP-binding enzyme family protein 0.0026 0.009 0.0133
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0033 0.0131 0.0442
Schistosoma mansoni hypothetical protein 0.0104 0.0572 0.0841
Echinococcus multilocularis Niemann Pick C1 protein 0.028 0.1674 0.167
Echinococcus multilocularis rhodopsin orphan GPCR 0.0016 0.0027 0.0023
Entamoeba histolytica cysteine proteinase, putative 0.0033 0.0131 0.0569
Brugia malayi aminoadipate-semialdehyde dehydrogenase-phosphopantetheinyl transferase 0.0085 0.0454 0.0672
Onchocerca volvulus 0.0033 0.0131 0.0348
Onchocerca volvulus 0.0021 0.0057 0.0151
Echinococcus granulosus expressed protein 0.0018 0.0036 0.0047
Brugia malayi Tachykinin-like peptides receptor 99D 0.0016 0.0027 0.0039
Trypanosoma cruzi cysteine peptidase, Clan CA, family C2, putative 0.0104 0.0572 0.0784
Brugia malayi neuropeptide F receptor 0.0016 0.0027 0.0039
Echinococcus multilocularis neuropeptide Y receptor 0.0016 0.0027 0.0023
Echinococcus granulosus somatostatin receptor 0.0016 0.0027 0.0033
Plasmodium falciparum AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.0019 0.0045 0.0414
Trypanosoma cruzi cysteine peptidase, Clan CA, family C2, putative 0.0104 0.0572 0.0784
Schistosoma mansoni opsin-like receptor 0.0016 0.0027 0.0033
Toxoplasma gondii EF hand domain-containing protein 0.0045 0.0205 0.0937
Brugia malayi AKH receptor 0.0016 0.0027 0.0039
Echinococcus granulosus neuropeptide FF receptor 2 0.0016 0.0027 0.0033
Trypanosoma cruzi hypothetical protein, conserved 0.0049 0.0229 0.0274
Brugia malayi hypothetical protein 0.0021 0.0057 0.0084
Leishmania major cathepsin L-like protease 0.0033 0.0131 0.0398
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.0104 0.0572 0.245
Loa Loa (eye worm) hypothetical protein 0.0016 0.0027 0.0039
Wolbachia endosymbiont of Brugia malayi exonuclease III 0.0019 0.0045 0.2411
Brugia malayi RE15519p 0.0016 0.0027 0.0039
Echinococcus multilocularis dro:myosuppressin receptor 0.0016 0.0027 0.0023
Trichomonas vaginalis Clan CA, family C1, cathepsin B-like cysteine peptidase 0.0033 0.0131 0.0442
Schistosoma mansoni patched 1 0.0084 0.0451 0.0661
Trypanosoma brucei kinesin, putative 0.0261 0.155 0.6994
Onchocerca volvulus 0.0016 0.0027 0.0071
Loa Loa (eye worm) hypothetical protein 0.0033 0.0131 0.0194
Trypanosoma cruzi centrin-3 0.0048 0.0227 0.027
Trichomonas vaginalis Crustacean calcium-binding protein, putative 0.0045 0.0205 0.0785
Onchocerca volvulus Dopamine\/Ecdysteroid receptor homolog 0.0016 0.0027 0.0071
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD7 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0019 0.0042 0.0251
Trichomonas vaginalis conserved hypothetical protein 0.0021 0.0057 0.0097
Trypanosoma cruzi calmodulin, putative 0.0045 0.0205 0.0237
Schistosoma mansoni rab 0.0045 0.0205 0.0297
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.0104 0.0572 0.245
Toxoplasma gondii hypothetical protein 0.0139 0.0793 0.3633
Echinococcus multilocularis calpain A 0.1024 0.631 0.6309
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0045 0.0205 0.0297
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0033 0.0131 0.0442
Schistosoma mansoni cpg binding protein 0.0032 0.0125 0.0178
Schistosoma mansoni geranylgeranyl transferase type I beta subunit 0.0036 0.0147 0.0212
Brugia malayi cathepsin L-like precursor 0.0033 0.0131 0.0194
Trypanosoma cruzi cysteine peptidase C (CPC), putative 0.1097 0.6766 1
Schistosoma mansoni dipeptidyl-peptidase I (C01 family) 0.0033 0.0131 0.0188
Trypanosoma cruzi calpain-like cysteine peptidase, putative 0.0104 0.0572 0.0784
Trypanosoma cruzi calpain-like cysteine peptidase, putative 0.0104 0.0572 0.0784
Leishmania major i/6 autoantigen-like protein 0.0045 0.0205 0.074
Trichomonas vaginalis myosin light chain 1, putative 0.0045 0.0205 0.0785
Trypanosoma cruzi cytoskeleton-associated protein CAP5.5, putative 0.0104 0.0572 0.0784
Echinococcus granulosus DNA apurinic or apyrimidinic site lyase 0.0019 0.0045 0.0061
Entamoeba histolytica cysteine proteinase 1, putative 0.0033 0.0131 0.0569
Schistosoma mansoni centrin 0.0045 0.0205 0.0297
Trypanosoma cruzi protein farnesyltransferase, putative 0.0131 0.0743 0.1037
Brugia malayi Helix-loop-helix DNA-binding domain containing protein 0.011 0.0612 0.0905
Brugia malayi cathepsin F-like cysteine proteinase 0.0033 0.0131 0.0194
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0033 0.0131 0.0442
Brugia malayi Serotonin receptor 0.0479 0.291 0.43
Schistosoma mansoni peptide (FMRFamide/somatostatin)-like receptor 0.0016 0.0027 0.0033
Echinococcus multilocularis protein prenyltransferase alpha subunit 0.0049 0.0229 0.0225
Trypanosoma cruzi cysteine proteinase, putative 0.0033 0.0131 0.0127
Onchocerca volvulus 0.0016 0.0027 0.0071
Trypanosoma brucei calpain-like cysteine peptidase, putative 0.0104 0.0572 0.245
Mycobacterium ulcerans hypothetical protein 0.0026 0.009 1
Trypanosoma cruzi conserved protein 0.0104 0.0572 0.0784
Echinococcus granulosus calpain 0.0364 0.2197 0.3243
Giardia lamblia Cathepsin B precursor 0.0362 0.2183 1
Brugia malayi programmed cell death protein 6 0.0045 0.0205 0.0302
Loa Loa (eye worm) hypothetical protein 0.0016 0.0027 0.0039
Echinococcus granulosus neuropeptide Y receptor 0.0016 0.0027 0.0033
Loa Loa (eye worm) hypothetical protein 0.0028 0.01 0.0148
Echinococcus multilocularis sex peptide receptor 0.0016 0.0027 0.0023
Giardia lamblia Cathepsin L precursor 0.0033 0.0131 0.0401
Mycobacterium ulcerans acyl-CoA synthetase 0.0026 0.009 1
Giardia lamblia Cathepsin B precursor 0.0362 0.2183 1
Echinococcus multilocularis ferritin 0.0018 0.0036 0.0032
Onchocerca volvulus Cathepsin L homolog 0.0033 0.0131 0.0348
Leishmania major calpain-like protein, putative,cysteine peptidase, Clan CA, family C2, putative 0.0104 0.0572 0.245
Echinococcus multilocularis programmed cell death protein 0.0048 0.0227 0.0223
Loa Loa (eye worm) hypothetical protein 0.0051 0.0243 0.0359
Schistosoma mansoni ferritin light chain 0.0018 0.0036 0.0047
Trypanosoma cruzi cruzipain precursor, putative 0.0033 0.0131 0.0127
Trichomonas vaginalis Clan CA, family C2, calpain-like cysteine peptidase 0.0104 0.0572 0.2498
Loa Loa (eye worm) hypothetical protein 0.0016 0.0027 0.0039
Loa Loa (eye worm) hypothetical protein 0.0016 0.0027 0.0039
Entamoeba histolytica hypothetical protein 0.0033 0.0131 0.0569
Leishmania major protein farnesyltransferase alpha subunit, putative 0.0049 0.0229 0.0855
Loa Loa (eye worm) hypothetical protein 0.0016 0.0027 0.0039
Brugia malayi sulfakinin receptor protein 0.0016 0.0027 0.0039
Schistosoma mansoni biogenic amine (octopamine/dopamine) receptor 0.0016 0.0027 0.0033
Loa Loa (eye worm) hypothetical protein 0.0033 0.0131 0.0194
Echinococcus granulosus orexin receptor type 2 0.0016 0.0027 0.0033
Echinococcus multilocularis neuropeptide Y receptor 0.0016 0.0027 0.0023
Entamoeba histolytica cysteine proteinase, putative 0.0033 0.0131 0.0569
Trichomonas vaginalis calmodulin, putative 0.0045 0.0205 0.0785
Echinococcus multilocularis neurocalcin 0.0045 0.0205 0.0201
Loa Loa (eye worm) G-protein coupled receptor 0.0016 0.0027 0.0039
Brugia malayi Pax transcription activation domain interacting protein 0.0021 0.0057 0.0084
Trichomonas vaginalis calmodulin-2, putative 0.0045 0.0205 0.0785
Echinococcus granulosus biogenic amine 5HT receptor 0.0016 0.0027 0.0033
Loa Loa (eye worm) hypothetical protein 0.002 0.0048 0.0072
Leishmania major eukaryotic initiation factor 4a, putative 0.0053 0.0257 0.0984
Plasmodium falciparum holo-[acyl-carrier-protein] synthase, putative 0.0024 0.0075 0.0679
Onchocerca volvulus 0.0016 0.0027 0.0071
Echinococcus multilocularis calumenin 0.0045 0.0205 0.0201
Echinococcus multilocularis protein farnesyltransferase alpha subunit 0.0188 0.1097 0.1093
Leishmania major hypothetical protein, conserved 0.0104 0.0572 0.245
Trypanosoma brucei centrin, putative 0.0045 0.0205 0.074
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.0104 0.0572 0.245
Echinococcus granulosus cathepsin b 0.1097 0.6766 1
Echinococcus multilocularis rhodopsin orphan GPCR 0.0016 0.0027 0.0023
Schistosoma mansoni neuropeptide receptor 0.0016 0.0027 0.0033
Plasmodium vivax hypothetical protein, conserved 0.0045 0.0205 0.0932
Trypanosoma brucei calpain-like cysteine peptidase, putative 0.0364 0.2197 1
Brugia malayi Dopamine receptor 0.0016 0.0027 0.0039
Brugia malayi calpain family protein 1 0.0979 0.6031 0.8914
Loa Loa (eye worm) hypothetical protein 0.0016 0.0027 0.0039
Echinococcus granulosus EF HAND 1 calcium binding site 0.0045 0.0205 0.0297
Echinococcus granulosus muscleblind protein 0.0152 0.0876 0.1289
Mycobacterium tuberculosis Halimadienyl diphosphate synthase 0.0036 0.0147 0.5034
Brugia malayi calcium-independent alpha-latrotoxin receptor 2, putative 0.0016 0.0026 0.0039
Trichomonas vaginalis calcium binding protein, putative 0.0045 0.0205 0.0785
Schistosoma mansoni neuronal calcium sensor 0.0045 0.0205 0.0297
Loa Loa (eye worm) hypothetical protein 0.0016 0.0027 0.0039
Brugia malayi hypothetical protein 0.0016 0.0027 0.0039
Leishmania major eukaryotic initiation factor 4a, putative 0.0053 0.0257 0.0984
Brugia malayi cathepsin B-like cysteine proteinase 0.1097 0.6766 1
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0033 0.0131 0.0442
Mycobacterium ulcerans fatty-acid-CoA ligase 0.0026 0.009 1
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0016 0.0027 0.0023
Echinococcus multilocularis neuropeptides capa receptor 0.0016 0.0027 0.0023
Schistosoma mansoni topbp1 0.0021 0.0057 0.0078
Echinococcus multilocularis neuropeptides capa receptor 0.0016 0.0027 0.0023
Trypanosoma cruzi cysteine peptidase, Clan CA, family C2, putative 0.0104 0.0572 0.0784
Loa Loa (eye worm) helix-loop-helix DNA-binding domain-containing protein 0.011 0.0609 0.09
Entamoeba histolytica calcium binding family protein 0.0045 0.0205 0.1058
Brugia malayi hypothetical protein 0.0018 0.0038 0.0057
Echinococcus multilocularis cathepsin b 0.1097 0.6766 0.6765
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0033 0.0131 0.0442
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0031 0.012 0.0171
Schistosoma mansoni neuronal calcium sensor 0.0045 0.0205 0.0297
Trichomonas vaginalis protein farnesyltransferase alpha subunit/RAB geranylgeranyl transferase alpha subunit, putative 0.0188 0.1097 0.4939
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0033 0.0131 0.0442
Echinococcus granulosus calbindin 32 0.0045 0.0205 0.0297
Brugia malayi Dopamine receptor protein 2 0.0016 0.0027 0.0039
Schistosoma mansoni biogenic amine receptor 0.0016 0.0027 0.0033
Echinococcus multilocularis calcium uptake protein 1 0.0045 0.0205 0.0201
Entamoeba histolytica cysteine protease, putative 0.0033 0.0131 0.0569
Schistosoma mansoni subfamily C1A unassigned peptidase (C01 family) 0.0033 0.0131 0.0188
Trypanosoma brucei lanosterol synthase 0.0036 0.0147 0.0474
Echinococcus multilocularis g protein coupled receptor 0.0016 0.0027 0.0023
Plasmodium falciparum dipeptidyl aminopeptidase 3 0.0033 0.0131 0.1195
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.0033 0.0131 0.0188
Loa Loa (eye worm) hypothetical protein 0.0016 0.0027 0.0039
Entamoeba histolytica cysteine protease, putative 0.0033 0.0131 0.0569
Echinococcus multilocularis programmed cell death protein 0.0048 0.0227 0.0223
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0033 0.0131 0.0442
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0033 0.0131 0.0442
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.0104 0.0572 0.245
Loa Loa (eye worm) papain family cysteine protease containing protein 0.0033 0.0131 0.0194
Onchocerca volvulus 0.0016 0.0027 0.0071
Onchocerca volvulus 0.0085 0.0454 0.1209
Loa Loa (eye worm) hypothetical protein 0.0016 0.0027 0.0039
Echinococcus multilocularis calmodulin 0.0045 0.0205 0.0201
Leishmania major cathepsin L-like protease 0.0033 0.0131 0.0398
Plasmodium vivax AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.0019 0.0045 0.0207
Brugia malayi Dopamine receptor protein 1, putative (partial) 0.0016 0.0027 0.0039
Loa Loa (eye worm) hypothetical protein 0.0471 0.2864 0.4232
Echinococcus granulosus calmodulin 0.0045 0.0205 0.0297
Trichomonas vaginalis DEAD box ATP-dependent RNA helicase, putative 0.0053 0.0257 0.1029
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0045 0.0205 0.0201
Echinococcus granulosus allatostatin A receptor 0.0016 0.0027 0.0033
Plasmodium falciparum serine repeat antigen 3 0.0033 0.0131 0.1195
Mycobacterium tuberculosis Probable cold-shock DeaD-box protein A homolog DeaD (ATP-dependent RNA helicase dead homolog) 0.0053 0.0257 1
Brugia malayi Melatonin receptor type 1A 0.0016 0.0027 0.0039
Echinococcus multilocularis calmodulin 0.0045 0.0205 0.0201
Loa Loa (eye worm) hypothetical protein 0.0016 0.0027 0.0039
Echinococcus multilocularis g protein linked acetylcholine receptor gar 2a 0.0016 0.0027 0.0023
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0033 0.0131 0.0398
Echinococcus multilocularis somatostatin receptor 0.0016 0.0027 0.0023
Mycobacterium tuberculosis Probable exodeoxyribonuclease III protein XthA (exonuclease III) (EXO III) (AP endonuclease VI) 0.0019 0.0045 0.0418
Trichomonas vaginalis calmodulin, putative 0.0045 0.0205 0.0785
Entamoeba histolytica acyl-coA synthetase, putative 0.0026 0.009 0.0295
Leishmania major calmodulin-like protein 0.0045 0.0205 0.074
Onchocerca volvulus Cathepsin F homolog 0.0033 0.0131 0.0348
Trichomonas vaginalis conserved hypothetical protein 0.0045 0.0205 0.0785
Brugia malayi Calmodulin-like protein 0.0045 0.0205 0.0302
Trypanosoma cruzi major cysteine proteinase, putative 0.0033 0.0131 0.0127
Trypanosoma cruzi cysteine peptidase, putative 0.0033 0.0131 0.0127
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0033 0.0131 0.0442
Echinococcus granulosus g-protein coupled receptor 0.0016 0.0027 0.0033
Mycobacterium ulcerans long-chain-fatty-acid-CoA ligase 0.0026 0.009 1
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD3 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0019 0.0042 0.0251
Leishmania major programmed cell death 6 protein-like protein 0.0045 0.0205 0.074
Trypanosoma brucei cysteine peptidase C (CPC) 0.0362 0.2183 0.9937
Loa Loa (eye worm) hypothetical protein 0.0036 0.0147 0.0218
Leishmania major cathepsin L-like protease 0.0033 0.0131 0.0398
Echinococcus granulosus tm gpcr rhodopsin 0.0016 0.0027 0.0033
Trypanosoma brucei calmodulin, putative 0.0045 0.0205 0.074
Plasmodium falciparum acyl-CoA synthetase 0.002 0.0048 0.0441
Plasmodium vivax serine-repeat antigen 4 (SERA), putative 0.0033 0.0131 0.0597
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0033 0.0131 0.0442
Schistosoma mansoni centrin-related 0.0045 0.0205 0.0297
Brugia malayi Protein prenyltransferase alpha subunit repeat containing protein 0.0049 0.0229 0.0339
Schistosoma mansoni cellular tumor antigen P53 0.0048 0.0224 0.0325
Loa Loa (eye worm) calpain family protein 1 0.0719 0.4407 0.6513
Entamoeba histolytica Rab geranylgeranyltransferase beta subunit, putative 0.0036 0.0147 0.0678
Plasmodium vivax vivapain-2 0.0033 0.0131 0.0597
Onchocerca volvulus 0.0032 0.0125 0.0331
Leishmania major 4-coumarate:coa ligase-like protein 0.0026 0.009 0.0207
Echinococcus multilocularis expressed protein 0.0018 0.0036 0.0032
Trypanosoma brucei hypothetical protein 0.0104 0.0572 0.245
Echinococcus multilocularis eukaryotic initiation factor 4A 0.0053 0.0257 0.0253
Echinococcus granulosus Niemann Pick C1 protein 0.028 0.1674 0.2469
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.0362 0.2183 0.3222
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0033 0.0131 0.0398
Trypanosoma cruzi cysteine protease, putative 0.0033 0.0131 0.0127
Giardia lamblia Cathepsin B-like cysteine proteinase 3 precursor 0.0033 0.0131 0.0401
Leishmania major centrin, putative,caltractin, putative 0.0045 0.0205 0.074
Trypanosoma cruzi cysteine peptidase, Clan CA, family C2, putative 0.0364 0.2197 0.3201
Plasmodium vivax unspecified product 0.0033 0.0131 0.0597
Schistosoma mansoni ferritin 0.0018 0.0036 0.0047
Trichomonas vaginalis calcineurin B subunit, putative 0.0045 0.0205 0.0785
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0033 0.0131 0.0398
Schistosoma mansoni neuronal calcium sensor 0.0045 0.0205 0.0297
Loa Loa (eye worm) prenyltransferase and squalene oxidase repeat family protein 0.0036 0.0147 0.0218
Trypanosoma brucei cysteine peptidase, Clan CA, family C2, putative 0.0104 0.0572 0.245
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD35 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0019 0.0042 0.0251
Trichomonas vaginalis calcineurin B subunit, putative 0.0045 0.0205 0.0785
Giardia lamblia Cysteine protease 0.0033 0.0131 0.0401
Trichomonas vaginalis protein farnesyltransferase alpha subunit/RAB geranylgeranyl transferase alpha subunit, putative 0.0139 0.0793 0.3525
Mycobacterium leprae conserved hypothetical protein 0.0024 0.0075 0.7141
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0016 0.0027 0.0033
Echinococcus granulosus dro:myosuppressin receptor 0.0016 0.0027 0.0033
Brugia malayi G protein-coupled receptor 0.0016 0.0027 0.0039
Trypanosoma brucei Calpain-like protein 1.2 0.0104 0.0572 0.245
Schistosoma mansoni amine GPCR 0.0016 0.0027 0.0033
Echinococcus multilocularis protein dispatched 1 0.0096 0.0525 0.0521
Schistosoma mansoni topbp1 0.0021 0.0057 0.0078
Echinococcus multilocularis fmrfamide receptor 0.0016 0.0027 0.0023
Loa Loa (eye worm) cysteine proteinase cathepsin Z 0.0033 0.0131 0.0194
Echinococcus multilocularis dnaJ subfamily B 0.0454 0.2756 0.2753
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.1097 0.6766 1
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0033 0.0131 0.0442
Echinococcus granulosus thyrotropin releasing hormone receptor 0.0016 0.0027 0.0033
Echinococcus granulosus geranylgeranyl transferase type 2 subunit alpha 0.0049 0.0229 0.0333
Plasmodium vivax vivapain-3 0.0033 0.0131 0.0597
Echinococcus multilocularis peptide (allatostatin:somatostatin) 0.0016 0.0027 0.0023
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0033 0.0131 0.0442
Onchocerca volvulus 0.0033 0.0131 0.0348
Entamoeba histolytica protein kinase, putative 0.0261 0.155 1
Schistosoma mansoni cathepsin F (C01 family) 0.0033 0.0131 0.0188
Loa Loa (eye worm) hypothetical protein 0.002 0.0048 0.0072
Brugia malayi hypothetical protein 0.0021 0.0057 0.0084
Trypanosoma cruzi kinesin, putative 0.0261 0.155 0.2239
Echinococcus granulosus L aminoadipate semialdehyde 0.0085 0.0454 0.0666
Schistosoma mansoni hypothetical protein 0.0016 0.0027 0.0033
Brugia malayi Prenyltransferase and squalene oxidase repeat family protein 0.0036 0.0147 0.0218
Brugia malayi Muscleblind-like protein 0.0152 0.0876 0.1294
Loa Loa (eye worm) hypothetical protein 0.0016 0.0027 0.0039
Echinococcus multilocularis sarcoplasmic calcium binding protein 0.0045 0.0205 0.0201
Loa Loa (eye worm) hypothetical protein 0.0104 0.0572 0.0846
Echinococcus granulosus calpain A 0.0364 0.2197 0.3243
Echinococcus granulosus neuropeptide receptor 0.0016 0.0027 0.0033
Echinococcus granulosus Niemann Pick C1 protein 0.0196 0.1149 0.1693
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0016 0.0027 0.0033
Plasmodium vivax prenyltransferase alpha subunit, putative 0.0188 0.1097 0.4992
Chlamydia trachomatis DNA ligase 0.0021 0.0057 0.3277
Trypanosoma brucei Eukaryotic initiation factor 4A-1 0.0053 0.0257 0.0984
Brugia malayi fibroinase precursor 0.0033 0.0131 0.0194
Loa Loa (eye worm) hypothetical protein 0.0016 0.0027 0.0039
Trichomonas vaginalis Clan CA, family C2, calpain-like cysteine peptidase 0.0104 0.0572 0.2498
Loa Loa (eye worm) hypothetical protein 0.0016 0.0027 0.0039
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0031 0.012 0.0171
Loa Loa (eye worm) calpain 0.0364 0.2197 0.3247
Giardia lamblia Cathepsin B precursor 0.0033 0.0131 0.0401
Brugia malayi putative neuropeptide receptor 0.0016 0.0027 0.0039
Echinococcus granulosus rhodopsin orphan GPCR 0.0016 0.0027 0.0033
Trichomonas vaginalis conserved hypothetical protein 0.0104 0.0572 0.2498
Toxoplasma gondii calcium-dependent protein kinase 0.0045 0.0205 0.0937
Trichomonas vaginalis protein farnesyltransferase alpha subunit, putative 0.0049 0.0229 0.09
Leishmania major calcineurin B subunit, putative 0.0045 0.0205 0.074
Loa Loa (eye worm) hypothetical protein 0.002 0.0048 0.0072
Loa Loa (eye worm) hypothetical protein 0.0016 0.0027 0.0039
Loa Loa (eye worm) hypothetical protein 0.0152 0.0876 0.1294
Loa Loa (eye worm) hypothetical protein 0.0188 0.1097 0.1621
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0033 0.0131 0.0442
Loa Loa (eye worm) hypothetical protein 0.0016 0.0027 0.0039
Echinococcus granulosus geranylgeranyl transferase type I beta subunit 0.0036 0.0147 0.0212
Trichomonas vaginalis Clan CA, family C2, calpain-like cysteine peptidase 0.0104 0.0572 0.2498
Loa Loa (eye worm) fibroinase 0.0033 0.0131 0.0194
Giardia lamblia Cathepsin B precursor 0.0033 0.0131 0.0401
Loa Loa (eye worm) hypothetical protein 0.0033 0.0131 0.0194
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0016 0.0027 0.0033
Plasmodium falciparum serine repeat antigen 7 0.0033 0.0131 0.1195
Trypanosoma cruzi calpain-like cysteine peptidase, putative 0.0104 0.0572 0.0784
Brugia malayi Cathepsin L-like precursor 0.0033 0.0131 0.0194
Plasmodium vivax calcium-dependent protein kinase 3, putative 0.0045 0.0205 0.0932
Giardia lamblia Replication factor C, subunit 1 0.0021 0.0057 0.0054
Trichomonas vaginalis type I geranylgeranyltransferase beta subunit, putative 0.0131 0.0743 0.329
Plasmodium falciparum ataxin-2 like protein, putative 0.0028 0.01 0.0914
Trypanosoma cruzi cysteine peptidase, clan CA, family C1, cathepsin L-like, putative 0.0033 0.0131 0.0127
Brugia malayi cahepsin L-like non-peptiedase homolog 0.0033 0.0131 0.0194
Loa Loa (eye worm) calpain family protein 1 0.0979 0.6031 0.8914
Schistosoma mansoni hypothetical protein 0.0016 0.0027 0.0033
Entamoeba histolytica Niemann-Pick C1 protein, putative 0.0196 0.1149 0.7334
Leishmania major hypothetical protein, conserved 0.0028 0.01 0.0255
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0033 0.0131 0.0442
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.0104 0.0572 0.245
Plasmodium falciparum serine repeat antigen 6 0.0033 0.0131 0.1195
Entamoeba histolytica hypothetical protein 0.0113 0.0632 0.3898
Echinococcus granulosus pyroglutamylated rfamide peptide receptor 0.0016 0.0027 0.0033
Trichomonas vaginalis DEAD box ATP-dependent RNA helicase, putative 0.0053 0.0257 0.1029
Trypanosoma brucei Calpain-like protein CALP1.3 0.0104 0.0572 0.245
Entamoeba histolytica cysteine proteinase, putative 0.0033 0.0131 0.0569
Mycobacterium leprae PROBABLE DNA LIGASE [NAD DEPENDENT] LIGA (POLYDEOXYRIBONUCLEOTIDE SYNTHASE [NAD+]) 0.0021 0.0057 0.3872
Echinococcus multilocularis g protein coupled receptor 0.0016 0.0027 0.0023
Trichomonas vaginalis Clan CA, family C2, calpain-like cysteine peptidase 0.0104 0.0572 0.2498
Loa Loa (eye worm) pre-SET domain-containing protein family protein 0.0213 0.1253 0.1853
Echinococcus multilocularis neuropeptide receptor 0.0016 0.0027 0.0023
Echinococcus multilocularis G protein coupled 5 hydroxytryptamine receptor 0.0016 0.0027 0.0023
Treponema pallidum DNA ligase (lig) 0.0021 0.0057 0.0941
Loa Loa (eye worm) G-protein-linked acetylcholine receptor protein 2 0.0016 0.0027 0.0039
Trypanosoma brucei cysteine peptidase, Clan CA, family C2, putative 0.0364 0.2197 1
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0033 0.0131 0.0442
Entamoeba histolytica cysteine proteinase, putative 0.0033 0.0131 0.0569
Trypanosoma brucei hypothetical protein, conserved 0.0045 0.0205 0.074
Trypanosoma brucei cytoskeleton-associated protein CAP5.5, putative 0.0104 0.0572 0.245
Trypanosoma brucei PAB1-binding protein , putative 0.0028 0.01 0.0255
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0033 0.0131 0.0442
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.1097 0.6766 1
Trypanosoma brucei centrin, putative 0.0045 0.0205 0.074
Trichomonas vaginalis DNA-dependent protein kinase catalytic subunit-interacting protein, putative 0.0045 0.0205 0.0785
Plasmodium falciparum cysteine proteinase falcipain 1 0.0033 0.0131 0.1195
Entamoeba histolytica hypothetical protein 0.0113 0.0632 0.3898
Schistosoma mansoni calmodulin related calcium binding protein 0.0045 0.0205 0.0297
Schistosoma mansoni muscarinic acetylcholine (GAR) receptor 0.0016 0.0027 0.0033
Trypanosoma brucei geranylgeranyl transferase type II beta subunit, putative 0.0036 0.0147 0.0474
Schistosoma mansoni neuropeptide F-like receptor 0.0016 0.0027 0.0033
Onchocerca volvulus 0.0016 0.0027 0.0071
Trichomonas vaginalis conserved hypothetical protein 0.0084 0.0451 0.1931
Loa Loa (eye worm) EF hand family protein 0.0045 0.0205 0.0302
Echinococcus multilocularis serotonin receptor 0.0016 0.0027 0.0023
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0033 0.0131 0.0442
Toxoplasma gondii eukaryotic initiation factor-4A, putative 0.0053 0.0257 0.1178
Loa Loa (eye worm) abnormal chemotaxis protein 14 0.0084 0.0451 0.0666
Leishmania major hypothetical protein, unknown function 0.0104 0.0572 0.245
Echinococcus granulosus protein prenyltransferase alpha subunit 0.0049 0.0229 0.0333
Brugia malayi G-protein coupled receptor 0.0016 0.0027 0.0039
Schistosoma mansoni hypothetical protein 0.0045 0.0205 0.0297
Loa Loa (eye worm) hypothetical protein 0.0021 0.0057 0.0084
Giardia lamblia Cathepsin L precursor 0.0033 0.0131 0.0401
Trypanosoma cruzi programmed cell death 6 protein-like, putative 0.0045 0.0205 0.0237
Trichomonas vaginalis Clan CA, family C2, calpain-like cysteine peptidase 0.0104 0.0572 0.2498
Toxoplasma gondii EFHC1, putative 0.0045 0.0205 0.0937
Brugia malayi Serotonin receptor 0.0016 0.0027 0.0039
Trichomonas vaginalis Clan CA, family C1, cathepsin F-like cysteine peptidase 0.0033 0.0131 0.0442
Giardia lamblia Cathepsin L precursor 0.0033 0.0131 0.0401
Schistosoma mansoni hypothetical protein 0.0081 0.0432 0.0633
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0033 0.0131 0.0442
Trypanosoma cruzi CAMK/CAMKL family protein kinase, putative 0.0045 0.0205 0.0237
Schistosoma mansoni peptide (allatostatin/somatostatin)-like receptor 0.0016 0.0027 0.0033
Trypanosoma cruzi cysteine peptidase, Clan CA, family C2, putative 0.0364 0.2197 0.3201
Giardia lamblia Rab geranylgeranyltransferase 0.0188 0.1097 0.4917
Entamoeba histolytica DEAD/DEAH box helicase, putative 0.0053 0.0257 0.1407
Trypanosoma brucei Protein prenyltransferase alpha subunit repeat, putative 0.0049 0.0229 0.0855
Toxoplasma gondii cathepsin CPL 0.0033 0.0131 0.06
Echinococcus granulosus growth hormone secretagogue receptor type 1 0.0016 0.0027 0.0033
Entamoeba histolytica cysteine protease, putative 0.0033 0.0131 0.0569
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0033 0.0131 0.0442
Echinococcus multilocularis thyrotropin releasing hormone receptor 0.0016 0.0027 0.0023
Entamoeba histolytica cysteine protease, putative 0.0033 0.0131 0.0569
Toxoplasma gondii hypothetical protein 0.0104 0.0572 0.2622
Brugia malayi Cathepsin L-like cysteine proteinase 0.0033 0.0131 0.0194
Schistosoma mansoni cathepsin C 0.0033 0.0131 0.0188
Brugia malayi Latrophilin receptor protein 2 0.0016 0.0026 0.0039
Entamoeba histolytica cysteine protease, putative 0.0033 0.0131 0.0569
Schistosoma mansoni hypothetical protein 0.0081 0.0432 0.0633
Trypanosoma cruzi cysteine proteinase, putative 0.0033 0.0131 0.0127
Onchocerca volvulus 0.0033 0.0131 0.0348
Toxoplasma gondii ATPase, AAA family protein 0.0021 0.0057 0.0261
Schistosoma mansoni opsin-like receptor 0.0016 0.0027 0.0033
Loa Loa (eye worm) hypothetical protein 0.0016 0.0027 0.0039
Trichomonas vaginalis calcium binding protein, putative 0.0045 0.0205 0.0785
Brugia malayi Papain family cysteine protease containing protein 0.0033 0.0131 0.0194
Trichomonas vaginalis calmodulin, putative 0.0045 0.0205 0.0785
Loa Loa (eye worm) prenyltransferase and squalene oxidase repeat family protein 0.0131 0.0743 0.1097
Echinococcus multilocularis tumor protein p63 0.0326 0.1961 0.1958
Giardia lamblia Cysteine protease 0.0033 0.0131 0.0401
Echinococcus granulosus cathepsin l1 0.0033 0.0131 0.0188
Loa Loa (eye worm) follicle stimulating hormone receptor 0.0016 0.0027 0.0039
Plasmodium falciparum cysteine proteinase falcipain 3 0.0033 0.0131 0.1195
Echinococcus multilocularis muscleblind protein 1 0.0152 0.0876 0.0872
Echinococcus granulosus tumor protein p63 0.0326 0.1961 0.2894
Wolbachia endosymbiont of Brugia malayi NAD-dependent DNA ligase, Lig 0.0021 0.0057 0.5422
Schistosoma mansoni family C2 unassigned peptidase (C02 family) 0.1024 0.631 0.9325
Echinococcus multilocularis transcription factor eb 0.011 0.0612 0.0608
Onchocerca volvulus 0.0096 0.0525 0.1396
Echinococcus granulosus sex peptide receptor 0.0016 0.0027 0.0033
Brugia malayi follicle stimulating hormone receptor 0.0016 0.0027 0.0039
Brugia malayi Corticotropin releasing factor receptor 2 precursor, putative 0.0051 0.0243 0.0359
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.0104 0.0572 0.245
Echinococcus multilocularis neuropeptide receptor 0.0016 0.0027 0.0023
Trichomonas vaginalis calmodulin, putative 0.0048 0.0227 0.089
Schistosoma mansoni biogenic amine (5HT) receptor 0.0016 0.0027 0.0033
Leishmania major cathepsin L-like protease 0.0033 0.0131 0.0398
Schistosoma mansoni cathepsin B (C01 family) 0.0033 0.0131 0.0188
Trichomonas vaginalis calmodulin, putative 0.0045 0.0205 0.0785
Trypanosoma cruzi caltractin, putative 0.0045 0.0205 0.0237
Brugia malayi G-protein coupled receptor 0.0016 0.0027 0.0039
Echinococcus granulosus neuronal calcium sensor 0.0045 0.0205 0.0297
Trichomonas vaginalis chromosome transmission fidelity factor, putative 0.0021 0.0057 0.0097
Leishmania major farnesyltransferase beta subunit 0.0131 0.0743 0.3241
Loa Loa (eye worm) hypothetical protein 0.0016 0.0027 0.0039
Trypanosoma cruzi calpain-like cysteine peptidase, putative 0.0364 0.2197 0.3201
Plasmodium falciparum serine repeat antigen 1 0.0033 0.0131 0.1195
Echinococcus granulosus G protein coupled 5 hydroxytryptamine receptor 0.0016 0.0027 0.0033
Brugia malayi cathepsin Z-like cysteine proteinase 0.0033 0.0131 0.0194
Echinococcus granulosus G protein coupled receptor 139 0.0016 0.0027 0.0033
Schistosoma mansoni tar DNA-binding protein 0.0134 0.0764 0.1123
Plasmodium vivax RNA helicase-1, putative 0.0053 0.0257 0.117
Entamoeba histolytica acyl-CoA synthetase, putative 0.0026 0.009 0.0295
Trypanosoma cruzi CAMK/CAMKL family protein kinase, putative 0.0045 0.0205 0.0237
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0033 0.0131 0.0442
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.0104 0.0572 0.245
Brugia malayi EF hand family protein 0.0045 0.0205 0.0302
Entamoeba histolytica papain family cysteine protease domain containing protein 0.0033 0.0131 0.0569
Brugia malayi Cathepsin L-like precursor 0.0033 0.0131 0.0194
Trypanosoma brucei hypothetical protein, conserved 0.0024 0.0075 0.0135
Trichomonas vaginalis protein farnesyltransferase alpha subunit, putative 0.0188 0.1097 0.4939
Echinococcus multilocularis rhodopsin orphan GPCR 0.0016 0.0027 0.0023
Mycobacterium ulcerans acyl-CoA synthetase 0.0026 0.009 1
Trichomonas vaginalis conserved hypothetical protein 0.0021 0.0057 0.0097
Echinococcus multilocularis cathepsin L 0.0033 0.0131 0.0127
Giardia lamblia Translation initiation factor eIF-4A, putative 0.0053 0.0257 0.099
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0033 0.0131 0.0442
Loa Loa (eye worm) hypothetical protein 0.0085 0.0454 0.0672
Echinococcus multilocularis cathepsin b 0.1097 0.6766 0.6765
Echinococcus granulosus tm gpcr rhodopsin 0.0016 0.0027 0.0033
Loa Loa (eye worm) hypothetical protein 0.0719 0.4407 0.6513
Loa Loa (eye worm) hypothetical protein 0.0035 0.0143 0.0211
Loa Loa (eye worm) hypothetical protein 0.0016 0.0027 0.0039
Leishmania major cysteine peptidase A (CPA) 0.0033 0.0131 0.0398
Loa Loa (eye worm) GTP-binding regulatory protein Gs alpha-S chain 0.0045 0.0205 0.0302
Entamoeba histolytica cysteine protease, putative 0.0033 0.0131 0.0569
Entamoeba histolytica cysteine proteinase, putative 0.0033 0.0131 0.0569
Brugia malayi CXXC zinc finger family protein 0.0032 0.0125 0.0184
Brugia malayi cathepsin Z-like cysteine proteinase 0.0033 0.0131 0.0194
Echinococcus granulosus fmrfamide receptor 0.0016 0.0027 0.0033
Brugia malayi hypothetical protein 0.0016 0.0027 0.0039
Entamoeba histolytica cysteine protease, putative 0.0033 0.0131 0.0569
Schistosoma mansoni amine GPCR 0.0016 0.0027 0.0033
Loa Loa (eye worm) hypothetical protein 0.0016 0.0027 0.0039
Plasmodium vivax holo-[acyl-carrier-protein] synthase, putative 0.0024 0.0075 0.0339
Schistosoma mansoni DEAD box ATP-dependent RNA helicase 0.0053 0.0257 0.0374
Entamoeba histolytica calmodulin, putative 0.0045 0.0205 0.1058
Echinococcus granulosus eukaryotic initiation factor 4A 0.0053 0.0257 0.0374
Echinococcus granulosus alpha 1A adrenergic receptor 0.0016 0.0027 0.0033
Entamoeba histolytica hypothetical protein 0.0113 0.0632 0.3898
Echinococcus granulosus hypothetical protein 0.0016 0.0027 0.0033
Echinococcus granulosus 7TM GPCR rhodopsin 0.0016 0.0027 0.0033
Echinococcus multilocularis muscleblind protein 0.0152 0.0876 0.0872
Plasmodium vivax serine-repeat antigen 2 (SERA) 0.0033 0.0131 0.0597
Loa Loa (eye worm) G-protein coupled receptor 0.0016 0.0027 0.0039
Schistosoma mansoni DEAD box ATP-dependent RNA helicase 0.0053 0.0257 0.0374
Schistosoma mansoni cathepsin S (C01 family) 0.0033 0.0131 0.0188
Echinococcus multilocularis G protein coupled receptor 139 0.0016 0.0027 0.0023
Loa Loa (eye worm) calmodulin-like protein 0.0045 0.0205 0.0302
Brugia malayi Probable protein farnesyltransferase beta subunit, putative 0.0036 0.0147 0.0218
Onchocerca volvulus 0.0033 0.0131 0.0348
Echinococcus multilocularis rhodopsin orphan GPCR 0.0016 0.0027 0.0023
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.0104 0.0572 0.245
Echinococcus multilocularis EF hand domain containing family member A2 0.0045 0.0205 0.0201
Entamoeba histolytica Activator 1 140 kDa subunit, putative 0.0021 0.0057 0.0077
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.0104 0.0572 0.245
Schistosoma mansoni biogenic amine (5HT) receptor 0.0016 0.0027 0.0033
Onchocerca volvulus 0.0045 0.0205 0.0544
Trichomonas vaginalis calmodulin, putative 0.0045 0.0205 0.0785
Plasmodium vivax serine-repeat antigen 3 (SERA) 0.0033 0.0131 0.0597
Echinococcus multilocularis L aminoadipate semialdehyde 0.0085 0.0454 0.0451
Echinococcus multilocularis g-protein coupled receptor 0.0016 0.0027 0.0023
Mycobacterium leprae PROBABLE FATTY-ACID-CoA LIGASE FADD2 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) 0.0026 0.009 1
Echinococcus granulosus rhodopsin orphan GPCR 0.0016 0.0027 0.0033
Entamoeba histolytica cysteine protease, putative 0.0033 0.0131 0.0569
Echinococcus granulosus histone lysine methyltransferase setb 0.0031 0.012 0.0171
Entamoeba histolytica hypothetical protein 0.0024 0.0075 0.0193
Trichomonas vaginalis Clan CA, family C1, cathepsin L or K-like cysteine peptidase 0.0033 0.0131 0.0442
Loa Loa (eye worm) hypothetical protein 0.0033 0.0131 0.0194
Echinococcus granulosus programmed cell death protein 0.0048 0.0227 0.033
Plasmodium vivax calpain, putative 0.0364 0.2197 1
Echinococcus granulosus tar DNA binding protein 0.0134 0.0764 0.1123
Trypanosoma cruzi cysteine peptidase, Clan CA, family C2, putative 0.0104 0.0572 0.0784
Echinococcus multilocularis calpain 0.0364 0.2197 0.2194
Trypanosoma cruzi Eukaryotic initiation factor 4A-1 0.0053 0.0257 0.0315
Trypanosoma cruzi calpain cysteine peptidase, putative 0.0364 0.2197 0.3201
Echinococcus granulosus g protein linked acetylcholine receptor gar 2a 0.0016 0.0027 0.0033
Plasmodium vivax geranylgeranyltransferase, putative 0.0036 0.0147 0.0671
Loa Loa (eye worm) hypothetical protein 0.0103 0.0569 0.0841
Onchocerca volvulus 0.0033 0.0131 0.0348
Brugia malayi Pre-SET motif family protein 0.0213 0.1253 0.1853
Schistosoma mansoni peptide (FMRFamide/somatostatin)-like receptor 0.0016 0.0027 0.0033
Trypanosoma cruzi cysteine peptidase, putative 0.0033 0.0131 0.0127
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0033 0.0131 0.0398
Loa Loa (eye worm) hypothetical protein 0.0033 0.0131 0.0194
Onchocerca volvulus 0.0049 0.0229 0.061
Echinococcus granulosus nibrin 0.0021 0.0057 0.0078
Entamoeba histolytica cysteine protease, putative 0.0033 0.0131 0.0569
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.0104 0.0572 0.245
Loa Loa (eye worm) hypothetical protein 0.0016 0.0027 0.0039
Plasmodium vivax vivapain-2 0.0033 0.0131 0.0597
Loa Loa (eye worm) pigment dispersing factor receptor c 0.0051 0.0243 0.0359
Toxoplasma gondii preprocathepsin c precursor, putative 0.0033 0.0131 0.06
Trichomonas vaginalis protein farnesyltransferase alpha subunit, putative 0.0188 0.1097 0.4939
Leishmania major calpain, putative,cysteine peptidase, Clan CA, family C2, putative 0.0364 0.2197 1
Loa Loa (eye worm) prenyltransferase alpha subunit repeat containing protein 0.0188 0.1097 0.1621
Trypanosoma brucei calmodulin, putative 0.0045 0.0205 0.074
Schistosoma mansoni hypothetical protein 0.0045 0.0205 0.0297
Loa Loa (eye worm) 5-hydroxytryptamine 2C receptor 0.0016 0.0027 0.0039
Echinococcus multilocularis EF hand domain containing family member A2 0.0045 0.0205 0.0201
Toxoplasma gondii Rab geranylgeranyl transferase type II beta subunit, putative 0.0036 0.0147 0.0675
Echinococcus multilocularis Niemann Pick C1 protein 0.0196 0.1149 0.1145
Toxoplasma gondii 4'-phosphopantetheinyl transferase domain-containing protein 0.0024 0.0075 0.0341
Trypanosoma cruzi PAB1-binding protein , putative 0.0028 0.01 0.0082
Schistosoma mansoni calpain (C02 family) 0.0364 0.2197 0.3243
Brugia malayi hypothetical protein 0.0016 0.0027 0.0039
Trypanosoma brucei caltractin, putative 0.0048 0.0227 0.0845
Plasmodium falciparum serine repeat antigen 4 0.0033 0.0131 0.1195
Giardia lamblia Hypothetical protein 0.0033 0.0131 0.0401
Giardia lamblia Cathepsin L-like protease 0.0033 0.0131 0.0401
Echinococcus multilocularis 7TM GPCR, rhodopsin 0.0016 0.0027 0.0023
Trypanosoma cruzi protein farnesyltransferase, putative 0.0131 0.0743 0.1037
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0016 0.0027 0.0033
Echinococcus multilocularis histone lysine methyltransferase setb histone lysine methyltransferase eggless 0.0031 0.012 0.0116
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0016 0.0027 0.0033
Trypanosoma cruzi BRCA1 C Terminus (BRCT) domain containing protein, putative 0.0021 0.0057 0.0017
Schistosoma mansoni tar DNA-binding protein 0.0134 0.0764 0.1123
Entamoeba histolytica cysteine protease, putative 0.0033 0.0131 0.0569
Brugia malayi cathepsin L precursor 0.0033 0.0131 0.0194
Plasmodium vivax unspecified product 0.0033 0.0131 0.0597
Loa Loa (eye worm) hypothetical protein 0.0016 0.0027 0.0039
Plasmodium vivax dipeptidyl aminopeptidase 3, putative 0.0033 0.0131 0.0597
Trypanosoma cruzi calpain-like cysteine peptidase, putative 0.0364 0.2197 0.3201
Trypanosoma brucei calpain, putative 0.0104 0.0572 0.245
Trypanosoma cruzi cysteine peptidase C (CPC), putative 0.0362 0.2183 0.3181
Onchocerca volvulus 0.0033 0.0131 0.0348
Echinococcus granulosus calpain 7 C02 family 0.0364 0.2197 0.3243
Onchocerca volvulus Cathepsin L homolog 0.0033 0.0131 0.0348
Leishmania major protein kinase, putative 0.0045 0.0205 0.074
Plasmodium vivax protein prenyltransferase alpha subunit, putative 0.0049 0.0229 0.1044
Plasmodium falciparum cysteine proteinase falcipain 2b 0.0033 0.0131 0.1195
Echinococcus multilocularis cpg binding protein 0.0034 0.0136 0.0132
Giardia lamblia Cathepsin B precursor 0.0362 0.2183 1
Brugia malayi Niemann-Pick C1 protein precursor 0.0196 0.1149 0.1698
Schistosoma mansoni neuropeptide receptor 0.0016 0.0027 0.0033
Loa Loa (eye worm) hypothetical protein 0.0016 0.0027 0.0039
Loa Loa (eye worm) hypothetical protein 0.0021 0.0057 0.0084
Giardia lamblia Cathepsin B precursor 0.0033 0.0131 0.0401
Entamoeba histolytica calpain family cysteine protease, putative 0.0104 0.0572 0.3502
Brugia malayi Papain family cysteine protease containing protein 0.0033 0.0131 0.0194
Trypanosoma brucei hypothetical protein, conserved 0.0049 0.0229 0.0855
Trypanosoma cruzi calpain-like cysteine peptidase, putative 0.0364 0.2197 0.3201
Schistosoma mansoni protein farnesyltransferase alpha subunit 0.0188 0.1097 0.1616
Echinococcus granulosus EF hand domain containing family member A2 0.0045 0.0205 0.0297
Entamoeba histolytica cysteine proteinase 2 0.0033 0.0131 0.0569
Echinococcus multilocularis eukaryotic initiation factor 4A III 0.0053 0.0257 0.0253
Loa Loa (eye worm) hypothetical protein 0.0016 0.0027 0.0039
Mycobacterium ulcerans acyl-CoA synthetase 0.0026 0.009 1
Loa Loa (eye worm) hypothetical protein 0.0045 0.0205 0.0302
Plasmodium vivax centrin-1, putative 0.0045 0.0205 0.0932
Entamoeba histolytica Rab geranylgeranyltransferase alpha subunit, putative 0.0049 0.0229 0.1223
Echinococcus multilocularis hypothetical protein 0.0364 0.2197 0.2194
Trypanosoma brucei CAMK/CAMKL family protein kinase, putative 0.0045 0.0205 0.074
Plasmodium vivax geranylgeranyl transferase type2 beta subunit, putative 0.0036 0.0147 0.0671
Plasmodium falciparum geranylgeranyltransferase, putative 0.0036 0.0147 0.1344
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0016 0.0027 0.0023
Trichomonas vaginalis Clan CA, family C1, cathepsin L, S or H-like cysteine peptidase 0.0033 0.0131 0.0442
Loa Loa (eye worm) hypothetical protein 0.0016 0.0027 0.0039
Trypanosoma cruzi major cysteine proteinase, putative 0.0033 0.0131 0.0127
Trypanosoma brucei cysteine peptidase, Clan CA, family C2, putative 0.0104 0.0572 0.245
Echinococcus multilocularis diuretic hormone 44 receptor GPRdih2 0.0016 0.0026 0.0022
Schistosoma mansoni hypothetical protein 0.0081 0.0432 0.0633
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0016 0.0027 0.0033
Trypanosoma cruzi Eukaryotic initiation factor 4A-1 0.0053 0.0257 0.0315
Trypanosoma cruzi kinesin, putative 0.0261 0.155 0.2239
Trypanosoma cruzi cysteine peptidase, Clan CA, family C2, putative 0.0104 0.0572 0.0784
Entamoeba histolytica grainin 2 0.0048 0.0227 0.1208
Plasmodium vivax farnesyltransferase beta subunit, putative 0.0131 0.0743 0.338
Leishmania major 4-coumarate:coa ligase-like protein 0.0026 0.009 0.0207
Entamoeba histolytica calpain large subunit domain III containing protein 0.0261 0.155 1
Trypanosoma cruzi cysteine peptidase, Clan CA, family C2, putative 0.0364 0.2197 0.3201
Leishmania major 4-coumarate:coa ligase-like protein 0.0026 0.009 0.0207
Echinococcus multilocularis protein patched 0.0084 0.0451 0.0447
Loa Loa (eye worm) calpain D 0.0104 0.0572 0.0846
Leishmania major hypothetical protein, conserved 0.0045 0.0205 0.074
Echinococcus multilocularis growth hormone secretagogue receptor type 1 0.0016 0.0027 0.0023
Schistosoma mansoni calmodulin 0.0045 0.0205 0.0297
Giardia lamblia Dipeptidyl-peptidase I precursor 0.0033 0.0131 0.0401
Toxoplasma gondii cathepsin CPC2 0.0033 0.0131 0.06
Loa Loa (eye worm) hypothetical protein 0.0876 0.5385 0.7958
Echinococcus multilocularis fmrfamide receptor 0.0016 0.0027 0.0023
Echinococcus multilocularis G-protein coupled receptor, putative 0.0016 0.0027 0.0023
Echinococcus granulosus transcription factor eb 0.011 0.0612 0.0899
Giardia lamblia Cathepsin L precursor 0.0033 0.0131 0.0401
Schistosoma mansoni apoferritin-2 0.0018 0.0036 0.0047
Brugia malayi hypothetical protein 0.0016 0.0027 0.0039
Echinococcus multilocularis calpain 5 0.0364 0.2197 0.2194
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0016 0.0027 0.0033
Trichomonas vaginalis geranylgeranyl transferase type I beta subunit, putative 0.0036 0.0147 0.0518
Onchocerca volvulus 0.0016 0.0027 0.0071
Toxoplasma gondii centrin, putative 0.0045 0.0205 0.0937
Giardia lamblia Cathepsin L precursor 0.0033 0.0131 0.0401
Loa Loa (eye worm) gonadotropin-releasing hormone receptor 2 0.0016 0.0027 0.0039
Plasmodium vivax replication factor C subunit 1, putative 0.0021 0.0057 0.0259
Schistosoma mansoni mitochondrial solute carrier 0.0045 0.0205 0.0297
Loa Loa (eye worm) hypothetical protein 0.0045 0.0205 0.0302
Brugia malayi ORL1-like opioid receptor 0.0016 0.0027 0.0039
Loa Loa (eye worm) hypothetical protein 0.0084 0.0451 0.0666
Giardia lamblia Cysteine protease 0.0033 0.0131 0.0401
Plasmodium falciparum serine repeat antigen 9 0.0033 0.0131 0.1195
Schistosoma mansoni ferritin light chain 0.0018 0.0036 0.0047
Entamoeba histolytica calcium-binding protein, putative 0.0045 0.0205 0.1058
Trypanosoma brucei I/6 autoantigen 0.0045 0.0205 0.074
Trypanosoma brucei calpain-like protein, putative 0.0364 0.2197 1
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0033 0.0131 0.0398
Trichomonas vaginalis ap endonuclease, putative 0.0019 0.0045 0.0043
Schistosoma mansoni SmCL2-like peptidase (C01 family) 0.0033 0.0131 0.0188
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0033 0.0131 0.0442
Trichomonas vaginalis calmodulin, putative 0.0045 0.0205 0.0785
Entamoeba histolytica hypothetical protein 0.0113 0.0632 0.3898
Onchocerca volvulus 0.0016 0.0027 0.0071
Loa Loa (eye worm) hypothetical protein 0.0016 0.0027 0.0039
Brugia malayi hypothetical protein 0.0016 0.0027 0.0039
Brugia malayi calpain family protein 1 0.0979 0.6031 0.8914
Schistosoma mansoni histamine-responsive GPCR (AAF21638) 0.0016 0.0027 0.0033
Mycobacterium ulcerans long-chain-fatty-acid--CoA ligase 0.0026 0.009 1
Trichomonas vaginalis conserved hypothetical protein 0.0021 0.0057 0.0097
Plasmodium vivax serine-repeat antigen (SERA) 0.0033 0.0131 0.0597
Plasmodium falciparum eukaryotic initiation factor 4A 0.0053 0.0257 0.2345
Schistosoma mansoni SmCL2-like peptidase (C01 family) 0.0033 0.0131 0.0188
Brugia malayi topoisomerase 0.0021 0.0057 0.0084
Onchocerca volvulus 0.0615 0.376 1
Brugia malayi hypothetical protein 0.0016 0.0027 0.0039
Giardia lamblia Hypothetical protein 0.0045 0.0205 0.0745
Entamoeba histolytica protein farnesyltransferase alpha subunit, putative 0.0188 0.1097 0.6986
Trypanosoma brucei antigen, putative 0.0364 0.2197 1
Echinococcus multilocularis calpain 7 (C02 family) 0.0364 0.2197 0.2194
Brugia malayi Papain family cysteine protease containing protein 0.0033 0.0131 0.0194
Trichomonas vaginalis centrin, putative 0.0045 0.0205 0.0785
Loa Loa (eye worm) latrophilin receptor protein 2 0.0016 0.0026 0.0039
Trichomonas vaginalis Clan CA, family C1, cathepsin B-like cysteine peptidase 0.0033 0.0131 0.0442
Loa Loa (eye worm) hypothetical protein 0.0026 0.009 0.0133
Onchocerca volvulus 0.0016 0.0027 0.0071
Schistosoma mansoni ef hand domain family member A2 0.0045 0.0205 0.0297
Loa Loa (eye worm) hypothetical protein 0.0021 0.0057 0.0084
Loa Loa (eye worm) exodeoxyribonuclease III family protein 0.0019 0.0045 0.0067
Entamoeba histolytica cysteine protease, putative 0.0033 0.0131 0.0569
Brugia malayi EF hand family protein 0.0045 0.0205 0.0302
Trypanosoma cruzi calpain-like cysteine peptidase, putative 0.0364 0.2197 0.3201
Trypanosoma cruzi mitochondrial calcium uptake 1, putative 0.0045 0.0205 0.0237
Brugia malayi Papain family cysteine protease containing protein 0.0033 0.0131 0.0194
Schistosoma mansoni biogenic amine receptor 0.0016 0.0027 0.0033
Echinococcus multilocularis neuropeptide receptor A26 0.0976 0.6014 0.6012
Schistosoma mansoni survival motor neuron protein 0.0096 0.0525 0.077
Echinococcus granulosus eukaryotic initiation factor 4A III 0.0053 0.0257 0.0374
Trichomonas vaginalis geranylgeranyl transferase type II beta subunit, putative 0.0131 0.0743 0.329
Plasmodium falciparum dipeptidyl aminopeptidase 2 0.0033 0.0131 0.1195
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.0104 0.0572 0.245
Giardia lamblia Hypothetical protein 0.0033 0.0131 0.0401
Echinococcus granulosus g protein coupled receptor 0.0016 0.0027 0.0033
Brugia malayi Papain family cysteine protease containing protein 0.0033 0.0131 0.0194
Loa Loa (eye worm) hypothetical protein 0.0016 0.0027 0.0039
Trypanosoma cruzi calpain-like cysteine peptidase, putative 0.0364 0.2197 0.3201
Schistosoma mansoni growth hormone secretagogue receptor 0.0016 0.0027 0.0033
Brugia malayi Iron-sulfur cluster assembly accessory protein 0.0096 0.0525 0.0776
Echinococcus multilocularis geranylgeranyl transferase type I beta subunit 0.0036 0.0147 0.0143
Brugia malayi hypothetical protein 0.0113 0.0632 0.0934
Leishmania major calpain family cysteine protease-like protein 0.0104 0.0572 0.245
Echinococcus multilocularis replication factor c subunit 1 0.0021 0.0057 0.0053
Entamoeba histolytica hypothetical protein, conserved 0.0045 0.0205 0.1058
Entamoeba histolytica grainin, putative 0.0045 0.0205 0.1058
Trypanosoma cruzi calpain-like cysteine peptidase, putative 0.0104 0.0572 0.0784
Brugia malayi Cathepsin L-like precursor 0.0033 0.0131 0.0194
Brugia malayi gonadotropin-releasing hormone receptor 2 0.0016 0.0027 0.0039
Trypanosoma cruzi cytoskeleton-associated protein CAP5.5, putative 0.0104 0.0572 0.0784
Echinococcus multilocularis biogenic amine (5HT) receptor 0.0016 0.0027 0.0023
Brugia malayi G protein-coupled receptor F59B2.13 0.0016 0.0027 0.0039
Brugia malayi TAR-binding protein 0.0134 0.0764 0.1129
Brugia malayi hypothetical protein 0.0471 0.2864 0.4232
Loa Loa (eye worm) hypothetical protein 0.0615 0.376 0.5557
Plasmodium falciparum ataxin-2 like protein, putative 0.0028 0.01 0.0914
Mycobacterium ulcerans phosphopantetheinyl transferase, PptII 0.0024 0.0075 0.7141
Trichomonas vaginalis calcium binding proteins, putative 0.0045 0.0205 0.0785
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0033 0.0131 0.0442
Loa Loa (eye worm) TAR-binding protein 0.0134 0.0764 0.1129
Trichomonas vaginalis protein farnesyltransferase beta subunit, putative 0.0036 0.0147 0.0518
Trypanosoma brucei mitochondrial calcium uptake 1 0.0045 0.0205 0.074
Toxoplasma gondii calpain family cysteine protease domain-containing protein 0.0104 0.0572 0.2622
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0033 0.0131 0.0398
Entamoeba histolytica cysteine protease, putative 0.0033 0.0131 0.0569
Loa Loa (eye worm) hypothetical protein 0.0033 0.0131 0.0194
Schistosoma mansoni calpain-7 (C02 family) 0.0364 0.2197 0.3243
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0033 0.0131 0.0398
Brugia malayi putative neuropeptide receptor NPR1 0.0016 0.0027 0.0039
Echinococcus granulosus replication factor c subunit 1 0.0021 0.0057 0.0078
Echinococcus granulosus Basic leucine zipper bZIP transcription 0.0113 0.0632 0.0929
Trichomonas vaginalis geranylgeranyl transferase type II beta subunit, putative 0.0131 0.0743 0.329
Brugia malayi Cathepsin L-like precursor 0.0033 0.0131 0.0194
Plasmodium falciparum geranylgeranyl transferase type2 beta subunit, putative 0.0036 0.0147 0.1344
Leishmania major cathepsin L-like protease 0.0033 0.0131 0.0398
Trypanosoma cruzi cysteine peptidase, Clan CA, family C2, putative 0.0364 0.2197 0.3201
Schistosoma mansoni geranylgeranyl transferase type II beta subunit 0.0036 0.0147 0.0212
Treponema pallidum 4'-phosphopantetheinyl transferase 0.0024 0.0075 0.1736
Onchocerca volvulus 0.0016 0.0027 0.0071
Trichomonas vaginalis conserved hypothetical protein 0.0033 0.0131 0.0442
Schistosoma mansoni protein farnesyltransferase subunit beta 0.0131 0.0743 0.1092
Echinococcus granulosus neuropeptide receptor 0.0016 0.0027 0.0033
Loa Loa (eye worm) programmed cell death protein 6 0.0045 0.0205 0.0302
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0045 0.0205 0.0297
Echinococcus granulosus ferritin 0.0018 0.0036 0.0047
Onchocerca volvulus 0.0033 0.0131 0.0348
Loa Loa (eye worm) hypothetical protein 0.0196 0.1149 0.1698
Trichomonas vaginalis chromosome transmission fidelity factor, putative 0.0021 0.0057 0.0097
Trypanosoma brucei glucosamine 6-phosphate n-acetyltransferase 0.0104 0.0572 0.245
Trichomonas vaginalis Clan CA, family C1, cathepsin L or H-like cysteine peptidase 0.0033 0.0131 0.0442
Echinococcus granulosus Protein patched homolog 1 0.0084 0.0451 0.0661
Onchocerca volvulus 0.0033 0.0131 0.0348
Echinococcus granulosus sterol regulatory element binding protein 0.0084 0.0451 0.0661
Loa Loa (eye worm) RNA binding protein 0.0134 0.0764 0.1129
Brugia malayi hypothetical protein 0.0016 0.0027 0.0039
Schistosoma mansoni geranylgeranyl transferase type I beta subunit 0.0036 0.0147 0.0212
Trichomonas vaginalis ap endonuclease, putative 0.0019 0.0045 0.0043
Trypanosoma cruzi calmodulin, putative 0.0045 0.0205 0.0237
Loa Loa (eye worm) hypothetical protein 0.0016 0.0027 0.0039
Echinococcus granulosus tm gpcr rhodopsin 0.0016 0.0027 0.0033
Brugia malayi latrophilin 2 splice variant baaae 0.0035 0.0143 0.0211
Trichomonas vaginalis conserved hypothetical protein 0.0033 0.0131 0.0442
Echinococcus multilocularis cathepsin l cysteine peptidase 0.0033 0.0131 0.0127
Trichomonas vaginalis DEAD box ATP-dependent RNA helicase, putative 0.0053 0.0257 0.1029
Brugia malayi calcium-binding protein 0.0045 0.0205 0.0302
Schistosoma mansoni cpg binding protein 0.0034 0.0136 0.0195
Trichomonas vaginalis calpain, putative 0.0104 0.0572 0.2498
Echinococcus multilocularis neuropeptide FF receptor 2 0.0016 0.0027 0.0023
Trypanosoma brucei calpain-like protein, putative 0.0364 0.2197 1
Mycobacterium ulcerans fatty-acid-CoA ligase 0.002 0.0048 0.2278
Trypanosoma cruzi cysteine peptidase, Clan CA, family C2, putative 0.0104 0.0572 0.0784
Plasmodium vivax dipeptidyl aminopeptidase 1, putative 0.0033 0.0131 0.0597
Onchocerca volvulus 0.0016 0.0027 0.0071
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0069 0.0354 0.0518
Trichomonas vaginalis hypothetical protein 0.0104 0.0572 0.2498
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0033 0.0131 0.0398
Echinococcus multilocularis cysteine protease 0.0033 0.0131 0.0127
Loa Loa (eye worm) hypothetical protein 0.0016 0.0027 0.0039
Echinococcus granulosus cpg binding protein 0.0034 0.0136 0.0195
Loa Loa (eye worm) hypothetical protein 0.0016 0.0027 0.0039
Schistosoma mansoni ferritin 0.0018 0.0036 0.0047
Toxoplasma gondii calmodulin CAM1 0.0045 0.0205 0.0937
Leishmania major centrin, putative 0.0045 0.0205 0.074
Loa Loa (eye worm) hypothetical protein 0.0016 0.0027 0.0039
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0033 0.0131 0.0398
Echinococcus granulosus cathepsin L cysteine protease 0.0033 0.0131 0.0188
Echinococcus granulosus tachykinin peptides receptor 99D 0.0016 0.0027 0.0033
Onchocerca volvulus 0.0045 0.0205 0.0544
Schistosoma mansoni amine GPCR 0.0016 0.0027 0.0033
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0016 0.0027 0.0033
Echinococcus granulosus biogenic amine 5HT receptor 0.0016 0.0027 0.0033
Brugia malayi Cathepsin L-like precursor 0.0033 0.0131 0.0194
Echinococcus multilocularis cysteine protease 0.0033 0.0131 0.0127
Brugia malayi Dopamine receptor protein 1 0.0016 0.0027 0.0039
Echinococcus multilocularis rhodopsin orphan GPCR 0.0016 0.0027 0.0023
Mycobacterium tuberculosis holo-[acyl-carrier protein] synthase AcpS (holo-ACP synthase) (CoA:APO-[ACP]pantetheinephosphotransferase) (CoA:APO-[acyl-carrie 0.0024 0.0075 0.1736
Trypanosoma cruzi PAB1-binding protein , putative 0.0028 0.01 0.0082
Entamoeba histolytica cysteine protease, putative 0.0033 0.0131 0.0569
Trichomonas vaginalis calcium binding protein, putative 0.0045 0.0205 0.0785
Trichomonas vaginalis Clan CA, family C1, cathepsin L or K-like cysteine peptidase 0.0033 0.0131 0.0442
Toxoplasma gondii cathepsin CPC1 0.0033 0.0131 0.06
Echinococcus multilocularis g protein coupled receptor 0.0016 0.0027 0.0023
Loa Loa (eye worm) hypothetical protein 0.0033 0.0131 0.0194
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0033 0.0131 0.0442
Trichomonas vaginalis Clan CA, family C2, calpain-like cysteine peptidase 0.0104 0.0572 0.2498
Plasmodium vivax serine-repeat antigen (SERA) 0.0033 0.0131 0.0597
Loa Loa (eye worm) neuropeptide F receptor 0.0016 0.0027 0.0039
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0033 0.0131 0.0442
Trypanosoma brucei BRCA1 C Terminus (BRCT) domain containing protein, putative 0.0021 0.0057 0.0054
Schistosoma mansoni hypothetical protein 0.0081 0.0432 0.0633
Trypanosoma cruzi Present in the outer mitochondrial membrane proteome 33 0.0045 0.0205 0.0237
Plasmodium falciparum calpain 0.0104 0.0572 0.522
Chlamydia trachomatis holo [acyl-carrier protein] synthase 0.0024 0.0075 1
Echinococcus multilocularis centrin 2 0.0045 0.0205 0.0201
Plasmodium falciparum protein farnesyltransferase subunit beta 0.0131 0.0743 0.6771
Toxoplasma gondii LsmAD domain-containing protein 0.0028 0.01 0.0459
Trypanosoma brucei centrin-3 0.0048 0.0227 0.0845
Brugia malayi neuropeptide F receptor 0.0016 0.0027 0.0039
Loa Loa (eye worm) hypothetical protein 0.002 0.0048 0.0072
Echinococcus granulosus calpain A 0.1024 0.631 0.9325
Onchocerca volvulus 0.0016 0.0027 0.0071
Schistosoma mansoni SmCL2-like peptidase (C01 family) 0.0033 0.0131 0.0188
Brugia malayi Prenyltransferase and squalene oxidase repeat family protein 0.0131 0.0743 0.1097
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0031 0.012 0.0171
Echinococcus multilocularis neuropeptide s receptor 0.0976 0.6014 0.6012
Echinococcus granulosus cysteine protease 0.0033 0.0131 0.0188
Echinococcus granulosus cathepsin L 0.0033 0.0131 0.0188
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0033 0.0131 0.0398
Loa Loa (eye worm) hypothetical protein 0.0016 0.0027 0.0039
Schistosoma mansoni chromosome transmission fidelity factor 0.0021 0.0057 0.0078
Echinococcus multilocularis cathepsin L cysteine protease 0.0033 0.0131 0.0127
Entamoeba histolytica cysteine protease, putative 0.0033 0.0131 0.0569
Plasmodium falciparum centrin-1 0.0045 0.0205 0.1866
Trichomonas vaginalis conserved hypothetical protein 0.0045 0.0205 0.0785
Brugia malayi AMP-binding enzyme family protein 0.0026 0.009 0.0133
Brugia malayi AMP-binding enzyme family protein 0.0026 0.009 0.0133
Entamoeba histolytica papain family cysteine protease domain containing protein 0.0033 0.0131 0.0569
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0033 0.0131 0.0442
Trypanosoma cruzi hypothetical protein, conserved 0.0036 0.0147 0.0152
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0016 0.0027 0.0023
Plasmodium vivax SET domain protein, putative 0.0031 0.012 0.0546
Trypanosoma brucei Present in the outer mitochondrial membrane proteome 33 0.0045 0.0205 0.074
Trypanosoma cruzi cysteine peptidase, putative 0.0033 0.0131 0.0127
Trypanosoma cruzi cysteine peptidase, putative 0.0033 0.0131 0.0127
Schistosoma mansoni reticulocalbin 0.0045 0.0205 0.0297
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0016 0.0027 0.0033
Echinococcus granulosus dnaJ subfamily B 0.0454 0.2756 0.4069
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0016 0.0027 0.0033
Echinococcus granulosus 7tm_1 domain containing protein 0.0016 0.0027 0.0033
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0033 0.0131 0.0442
Schistosoma mansoni opsin-like receptor 0.0016 0.0027 0.0033
Trypanosoma cruzi hypothetical protein, conserved 0.0049 0.0229 0.0274
Trichomonas vaginalis calpain, putative 0.0104 0.0572 0.2498
Trichomonas vaginalis replication factor C large subunit, putative 0.0021 0.0057 0.0097
Echinococcus multilocularis protein farnesyltransferase subunit beta 0.0131 0.0743 0.0739
Brugia malayi Cathepsin L-like precursor 0.0033 0.0131 0.0194
Trypanosoma cruzi cysteine peptidase, Clan CA, family C2, putative 0.0104 0.0572 0.0784
Schistosoma mansoni ferritin 0.0018 0.0036 0.0047
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0033 0.0131 0.0442
Brugia malayi G-protein-linked acetylcholine receptor protein 2, putative 0.0016 0.0027 0.0039
Loa Loa (eye worm) papain family cysteine protease containing protein 0.0033 0.0131 0.0194
Toxoplasma gondii histone lysine methyltransferase SET1 0.0061 0.0309 0.1417
Schistosoma mansoni amine GPCR 0.0016 0.0027 0.0033
Schistosoma mansoni peptide (allatostatin)-like receptor 0.0016 0.0027 0.0033
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0033 0.0131 0.0442
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0033 0.0131 0.0442
Onchocerca volvulus 0.0016 0.0027 0.0071
Trichomonas vaginalis conserved hypothetical protein 0.0021 0.0057 0.0097
Plasmodium vivax serine-repeat antigen 5 (SERA) 0.0033 0.0131 0.0597
Trypanosoma cruzi geranylgeranyl transferase type II beta subunit, putative 0.0036 0.0147 0.0152
Brugia malayi Pre-SET motif family protein 0.0031 0.012 0.0177
Trypanosoma cruzi cytoskeleton-associated protein CAP5.5, putative 0.0104 0.0572 0.0784
Entamoeba histolytica cysteine protease, putative 0.0033 0.0131 0.0569
Onchocerca volvulus 0.0026 0.009 0.0239
Echinococcus granulosus expressed conserved protein 0.0184 0.1075 0.1583
Brugia malayi Unidentified vitellogenin-linked transcript protein 6, putative 0.0016 0.0027 0.0039
Schistosoma mansoni cathepsin F (C01 family) 0.0033 0.0131 0.0188
Echinococcus granulosus cathepsin l1 0.0033 0.0131 0.0188
Entamoeba histolytica calmodulin, putative 0.0045 0.0205 0.1058
Echinococcus granulosus centrin 2 0.0045 0.0205 0.0297
Plasmodium falciparum protein farnesyltransferase subunit alpha 0.0188 0.1097 1
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0033 0.0131 0.0398
Echinococcus multilocularis sterol regulatory element binding protein 0.0084 0.0451 0.0447
Brugia malayi hypothetical protein 0.0016 0.0027 0.0039
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0045 0.0205 0.0297
Entamoeba histolytica cysteine protease, putative 0.0033 0.0131 0.0569
Schistosoma mansoni SmCB2 peptidase (C01 family) 0.1097 0.6766 1
Loa Loa (eye worm) hypothetical protein 0.0016 0.0027 0.0039
Echinococcus granulosus 5'partial|histone lysine N methyltransferase SETDB2 0.0029 0.0109 0.0155
Loa Loa (eye worm) melatonin receptor type 1A 0.0016 0.0027 0.0039
Brugia malayi cathepsin L-like cysteine proteinase 0.0033 0.0131 0.0194
Wolbachia endosymbiont of Brugia malayi 4'-phosphopantetheinyl transferase 0.0024 0.0075 1
Echinococcus multilocularis rhodopsin orphan GPCR 0.0016 0.0027 0.0023

Activities

Activity type Activity value Assay description Source Reference
GI (functional) = 0 % Antifungal activity against Candida albicans ATCC 10231 assessed as inhibition of fungal growth at 6.25 uM ChEMBL. 20620056
GI (functional) = 4 % Antifungal activity against Candida albicans ATCC 10231 assessed as inhibition of fungal growth at 12.5 uM ChEMBL. 20620056
GI (functional) = 60 % Antifungal activity against Cryptococcus neoformans ATCC 32264 assessed as inhibition of fungal growth at 6.25 uM ChEMBL. 20620056
GI (functional) = 90 % Antifungal activity against Cryptococcus neoformans ATCC 32264 assessed as inhibition of fungal growth at 12.5 uM ChEMBL. 20620056
GI (functional) = 91 % Antifungal activity against Candida albicans ATCC 10231 assessed as inhibition of fungal growth at 25 uM ChEMBL. 20620056
GI (functional) = 95 % Antifungal activity against Candida albicans ATCC 10231 assessed as inhibition of fungal growth at 50 uM ChEMBL. 20620056
GI (functional) = 100 % Antifungal activity against Cryptococcus neoformans ATCC 32264 assessed as inhibition of fungal growth at 25 uM ChEMBL. 20620056
GI (functional) = 100 % Antifungal activity against Cryptococcus neoformans ATCC 32264 assessed as inhibition of fungal growth at 50 uM ChEMBL. 20620056
GI (functional) = 100 % Antifungal activity against Cryptococcus neoformans ATCC 32264 assessed as inhibition of fungal growth at 100 uM ChEMBL. 20620056
GI (functional) = 100 % Antifungal activity against Cryptococcus neoformans ATCC 32264 assessed as inhibition of fungal growth at 200 uM ChEMBL. 20620056
GI (functional) = 100 % Antifungal activity against Candida albicans ATCC 10231 assessed as inhibition of fungal growth at 100 uM ChEMBL. 20620056
GI (functional) = 100 % Antifungal activity against Candida albicans ATCC 10231 assessed as inhibition of fungal growth at 200 uM ChEMBL. 20620056
IC50 (functional) 0 Antiproliferative activity against human MCF7 cell line by MTT assay after 72 hrs ChEMBL. 16513344
IC50 (functional) 0 Antiproliferative activity against human A549 cell line by MTT assay after 72 hrs ChEMBL. 16513344
Inhibition (functional) = 4 % Antifungal activity against Candida albicans ATCC 10231 assessed as growth inhibition at 12.5 uM after 24 hrs ChEMBL. 18430492
Inhibition (functional) = 90 % Antifungal activity against Cryptococcus neoformans ATCC 32264 assessed as growth inhibition at 12.5 uM after 48 hrs ChEMBL. 18430492
Inhibition (functional) = 91 % Antifungal activity against Candida albicans ATCC 10231 assessed as growth inhibition at 25 uM after 24 hrs ChEMBL. 18430492
Inhibition (functional) = 95 % Antifungal activity against Candida albicans ATCC 10231 assessed as growth inhibition at 50 uM after 24 hrs ChEMBL. 18430492
Inhibition (functional) = 100 % Antifungal activity against Candida albicans ATCC 10231 assessed as growth inhibition at 100 uM after 24 hrs ChEMBL. 18430492
Inhibition (functional) = 100 % Antifungal activity against Cryptococcus neoformans ATCC 32264 assessed as growth inhibition at 200 uM after 48 hrs ChEMBL. 18430492
Inhibition (functional) = 100 % Antifungal activity against Cryptococcus neoformans ATCC 32264 assessed as growth inhibition at 100 uM after 48 hrs ChEMBL. 18430492
Inhibition (functional) = 100 % Antifungal activity against Cryptococcus neoformans ATCC 32264 assessed as growth inhibition at 50 uM after 48 hrs ChEMBL. 18430492
Inhibition (functional) = 100 % Antifungal activity against Cryptococcus neoformans ATCC 32264 assessed as growth inhibition at 25 uM after 48 hrs ChEMBL. 18430492
Inhibition (functional) = 100 % Antifungal activity against Candida albicans ATCC 10231 assessed as growth inhibition at 200 uM after 24 hrs ChEMBL. 18430492
MIC (functional) = 2 uM Antimicrobial activity against Escherichia coli ChEMBL. 20696877

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
In any case, if you have information about papers containing relevant validation data for this target, please log in using your TDR Targets username and password and send them to us using the corresponding form in this page (only visible to registered users) or contact us.

External resources for this compound

Bibliographic References

1 literature reference was collected for this gene.

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