Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Trichomonas vaginalis | CAMK family protein kinase | 0.0092 | 0.067 | 0.0458 |
Entamoeba histolytica | cysteine protease, putative | 0.0195 | 0.1668 | 0.107 |
Echinococcus granulosus | bromodomain adjacent to zinc finger domain | 0.006 | 0.0359 | 0.0359 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.0195 | 0.1668 | 0.1479 |
Brugia malayi | cathepsin L-like cysteine proteinase, identical | 0.0349 | 0.316 | 0.3144 |
Onchocerca volvulus | 0.1055 | 1 | 1 | |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.1055 | 1 | 1 |
Trypanosoma cruzi | cysteine peptidase, putative | 0.0544 | 0.5046 | 0.469 |
Trichomonas vaginalis | CAMK family protein kinase | 0.0092 | 0.067 | 0.0458 |
Loa Loa (eye worm) | papain family cysteine protease containing protein | 0.1055 | 1 | 1 |
Trypanosoma brucei | cysteine peptidase C (CPC) | 0.0195 | 0.1668 | 0.107 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0544 | 0.5046 | 0.4933 |
Entamoeba histolytica | cysteine protease, putative | 0.0544 | 0.5046 | 0.469 |
Trypanosoma cruzi | major cysteine proteinase, putative | 0.0195 | 0.1668 | 0.107 |
Brugia malayi | Papain family cysteine protease containing protein | 0.0544 | 0.5046 | 0.5034 |
Brugia malayi | serine/threonine-protein kinase plk-2 | 0.0092 | 0.067 | 0.0648 |
Giardia lamblia | Cathepsin B precursor | 0.0195 | 0.1668 | 1 |
Trypanosoma cruzi | cysteine peptidase, putative | 0.1055 | 1 | 1 |
Schistosoma mansoni | SmCL2-like peptidase (C01 family) | 0.0544 | 0.5046 | 0.5046 |
Giardia lamblia | Cysteine protease | 0.0195 | 0.1668 | 1 |
Brugia malayi | Papain family cysteine protease containing protein | 0.0195 | 0.1668 | 0.1648 |
Trichomonas vaginalis | CAMK family protein kinase | 0.0092 | 0.067 | 0.0458 |
Echinococcus multilocularis | cathepsin L cysteine protease | 0.1055 | 1 | 1 |
Trichomonas vaginalis | CAMK family protein kinase | 0.0092 | 0.067 | 0.0458 |
Brugia malayi | Cathepsin L-like precursor | 0.1055 | 1 | 1 |
Giardia lamblia | Cathepsin L precursor | 0.0195 | 0.1668 | 1 |
Brugia malayi | Papain family cysteine protease containing protein | 0.1055 | 1 | 1 |
Entamoeba histolytica | cysteine protease, putative | 0.0195 | 0.1668 | 0.107 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin F-like cysteine peptidase | 0.0195 | 0.1668 | 0.1479 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.1055 | 1 | 1 |
Giardia lamblia | Hypothetical protein | 0.0195 | 0.1668 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0349 | 0.316 | 0.3054 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0706 | 0.6622 | 0.6546 |
Brugia malayi | Cathepsin L-like precursor | 0.0706 | 0.6622 | 0.6614 |
Entamoeba histolytica | cysteine proteinase 2 | 0.0544 | 0.5046 | 0.469 |
Loa Loa (eye worm) | hypothetical protein | 0.0706 | 0.6622 | 0.6569 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.1055 | 1 | 1 |
Loa Loa (eye worm) | PLK/PLK1 protein kinase | 0.0092 | 0.067 | 0.0524 |
Loa Loa (eye worm) | hypothetical protein | 0.0041 | 0.0176 | 0.0023 |
Echinococcus multilocularis | serine:threonine protein kinase PLK1 | 0.0092 | 0.067 | 0.067 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.1055 | 1 | 1 |
Plasmodium falciparum | cysteine proteinase falcipain 2a | 0.1055 | 1 | 1 |
Brugia malayi | Cathepsin L-like precursor | 0.0706 | 0.6622 | 0.6614 |
Loa Loa (eye worm) | hypothetical protein | 0.0195 | 0.1668 | 0.1538 |
Onchocerca volvulus | 0.0195 | 0.1668 | 0.107 | |
Trypanosoma cruzi | cysteine proteinase, putative | 0.0544 | 0.5046 | 0.469 |
Entamoeba histolytica | cysteine protease, putative | 0.0195 | 0.1668 | 0.107 |
Onchocerca volvulus | Cathepsin F homolog | 0.1055 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0195 | 0.1668 | 0.1538 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.1055 | 1 | 1 |
Onchocerca volvulus | Cathepsin L homolog | 0.0195 | 0.1668 | 0.107 |
Leishmania major | cathepsin L-like protease | 0.1055 | 1 | 1 |
Leishmania major | cathepsin L-like protease | 0.1055 | 1 | 1 |
Entamoeba histolytica | cysteine proteinase, putative | 0.0706 | 0.6622 | 0.638 |
Onchocerca volvulus | Cathepsin L homolog | 0.1055 | 1 | 1 |
Giardia lamblia | Cathepsin B precursor | 0.0195 | 0.1668 | 1 |
Echinococcus multilocularis | cathepsin l cysteine peptidase | 0.1055 | 1 | 1 |
Entamoeba histolytica | cysteine protease, putative | 0.0544 | 0.5046 | 0.469 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.0195 | 0.1668 | 0.1479 |
Schistosoma mansoni | SmCL2-like peptidase (C01 family) | 0.0544 | 0.5046 | 0.5046 |
Brugia malayi | Cathepsin L-like precursor | 0.0349 | 0.316 | 0.3144 |
Loa Loa (eye worm) | hypothetical protein | 0.0043 | 0.0194 | 0.0042 |
Leishmania major | cysteine peptidase C (CPC),CPC cysteine peptidase, Clan CA, family C1, Cathepsin B-like | 0.0195 | 0.1668 | 0.107 |
Echinococcus granulosus | cathepsin L | 0.0544 | 0.5046 | 0.5046 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.1055 | 1 | 1 |
Entamoeba histolytica | cysteine proteinase, putative | 0.0544 | 0.5046 | 0.469 |
Schistosoma mansoni | hypothetical protein | 0.0334 | 0.3014 | 0.3014 |
Brugia malayi | Cathepsin L-like precursor | 0.1055 | 1 | 1 |
Schistosoma mansoni | cathepsin B-like peptidase (C01 family) | 0.0195 | 0.1668 | 0.1668 |
Entamoeba histolytica | cysteine protease, putative | 0.0544 | 0.5046 | 0.469 |
Plasmodium vivax | vivapain-2 | 0.1055 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0195 | 0.1668 | 0.1538 |
Plasmodium falciparum | cysteine proteinase falcipain 1 | 0.0544 | 0.5046 | 0.4054 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.1055 | 1 | 1 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.1055 | 1 | 1 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0195 | 0.1668 | 0.1479 |
Entamoeba histolytica | cysteine protease, putative | 0.0195 | 0.1668 | 0.107 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin B-like cysteine peptidase | 0.0195 | 0.1668 | 0.1479 |
Plasmodium falciparum | cysteine proteinase falcipain 3 | 0.1055 | 1 | 1 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin B-like cysteine peptidase | 0.0195 | 0.1668 | 0.1479 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.1055 | 1 | 1 |
Leishmania major | cathepsin L-like protease | 0.1055 | 1 | 1 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.0195 | 0.1668 | 0.1479 |
Onchocerca volvulus | 0.0706 | 0.6622 | 0.638 | |
Trypanosoma cruzi | cysteine peptidase, putative | 0.0349 | 0.316 | 0.2669 |
Giardia lamblia | Cathepsin L precursor | 0.0195 | 0.1668 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0195 | 0.1668 | 0.1538 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L or K-like cysteine peptidase | 0.1055 | 1 | 1 |
Schistosoma mansoni | cathepsin B-like peptidase (C01 family) | 0.0195 | 0.1668 | 0.1668 |
Giardia lamblia | Cathepsin L precursor | 0.0195 | 0.1668 | 1 |
Plasmodium vivax | vivapain-2 | 0.1055 | 1 | 1 |
Onchocerca volvulus | 0.1055 | 1 | 1 | |
Giardia lamblia | Cathepsin B precursor | 0.0195 | 0.1668 | 1 |
Trypanosoma cruzi | cysteine peptidase, putative | 0.1055 | 1 | 1 |
Brugia malayi | cahepsin L-like non-peptiedase homolog | 0.0195 | 0.1668 | 0.1648 |
Plasmodium vivax | vivapain-1 | 0.0544 | 0.5046 | 0.4054 |
Echinococcus granulosus | cathepsin l1 | 0.1055 | 1 | 1 |
Echinococcus multilocularis | geminin | 0.0334 | 0.3014 | 0.3014 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.1055 | 1 | 1 |
Echinococcus granulosus | cathepsin b | 0.0195 | 0.1668 | 0.1668 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.1055 | 1 | 1 |
Loa Loa (eye worm) | papain family cysteine protease containing protein | 0.0349 | 0.316 | 0.3054 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L or H-like cysteine peptidase | 0.0195 | 0.1668 | 0.1479 |
Entamoeba histolytica | cysteine protease, putative | 0.0544 | 0.5046 | 0.469 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.1055 | 1 | 1 |
Onchocerca volvulus | Cathepsin L homolog | 0.1055 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.1055 | 1 | 1 |
Entamoeba histolytica | cysteine protease, putative | 0.0544 | 0.5046 | 0.469 |
Schistosoma mansoni | subfamily C1A non-peptidase homologue (C01 family) | 0.0195 | 0.1668 | 0.1668 |
Entamoeba histolytica | cysteine proteinase, putative | 0.1055 | 1 | 1 |
Entamoeba histolytica | cysteine protease, putative | 0.0544 | 0.5046 | 0.469 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.1055 | 1 | 1 |
Trichomonas vaginalis | CAMK family protein kinase | 0.0092 | 0.067 | 0.0458 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.1055 | 1 | 1 |
Echinococcus granulosus | bromodomain adjacent to zinc finger domain | 0.0036 | 0.013 | 0.013 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.1055 | 1 | 1 |
Entamoeba histolytica | cysteine proteinase, putative | 0.1055 | 1 | 1 |
Brugia malayi | Cathepsin L-like precursor | 0.1055 | 1 | 1 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.1055 | 1 | 1 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.1055 | 1 | 1 |
Schistosoma mansoni | cathepsin B-like peptidase (C01 family) | 0.0195 | 0.1668 | 0.1668 |
Leishmania major | cathepsin L-like protease | 0.1055 | 1 | 1 |
Entamoeba histolytica | cysteine proteinase 1, putative | 0.0544 | 0.5046 | 0.469 |
Entamoeba histolytica | cysteine protease, putative | 0.1055 | 1 | 1 |
Brugia malayi | Cathepsin L-like precursor | 0.1055 | 1 | 1 |
Plasmodium falciparum | cysteine proteinase falcipain 2b | 0.1055 | 1 | 1 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.1055 | 1 | 1 |
Trypanosoma cruzi | cysteine peptidase C (CPC), putative | 0.0195 | 0.1668 | 0.107 |
Schistosoma mansoni | bromodomain containing protein | 0.0063 | 0.0394 | 0.0394 |
Loa Loa (eye worm) | cysteine proteinase cathepsin Z | 0.0195 | 0.1668 | 0.1538 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.1055 | 1 | 1 |
Onchocerca volvulus | 0.1055 | 1 | 1 | |
Schistosoma mansoni | cathepsin C | 0.0195 | 0.1668 | 0.1668 |
Loa Loa (eye worm) | papain family cysteine protease containing protein | 0.0195 | 0.1668 | 0.1538 |
Plasmodium vivax | unspecified product | 0.0349 | 0.316 | 0.1791 |
Onchocerca volvulus | 0.1055 | 1 | 1 | |
Leishmania major | cysteine peptidase A (CPA) | 0.1055 | 1 | 1 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.1055 | 1 | 1 |
Entamoeba histolytica | papain family cysteine protease domain containing protein | 0.0195 | 0.1668 | 0.107 |
Giardia lamblia | Dipeptidyl-peptidase I precursor | 0.0195 | 0.1668 | 1 |
Giardia lamblia | Cathepsin B-like cysteine proteinase 3 precursor | 0.0195 | 0.1668 | 1 |
Schistosoma mansoni | kinase | 0.0047 | 0.0233 | 0.0233 |
Brugia malayi | Papain family cysteine protease containing protein | 0.0195 | 0.1668 | 0.1648 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0195 | 0.1668 | 0.1479 |
Echinococcus multilocularis | bromodomain adjacent to zinc finger domain | 0.006 | 0.0359 | 0.0359 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0195 | 0.1668 | 0.1479 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0195 | 0.1668 | 0.1479 |
Schistosoma mansoni | cathepsin B-like peptidase (C01 family) | 0.0195 | 0.1668 | 0.1668 |
Entamoeba histolytica | cysteine proteinase, putative | 0.0544 | 0.5046 | 0.469 |
Giardia lamblia | Cathepsin L-like protease | 0.0195 | 0.1668 | 1 |
Brugia malayi | cathepsin F-like cysteine proteinase | 0.0195 | 0.1668 | 0.1648 |
Entamoeba histolytica | cysteine protease, putative | 0.0544 | 0.5046 | 0.469 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.1055 | 1 | 1 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L or K-like cysteine peptidase | 0.1055 | 1 | 1 |
Schistosoma mansoni | cathepsin B-like peptidase (C01 family) | 0.0195 | 0.1668 | 0.1668 |
Echinococcus granulosus | cathepsin l1 | 0.0706 | 0.6622 | 0.6622 |
Brugia malayi | fibroinase precursor | 0.0195 | 0.1668 | 0.1648 |
Giardia lamblia | Cathepsin B precursor | 0.0195 | 0.1668 | 1 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.1055 | 1 | 1 |
Trypanosoma cruzi | cysteine peptidase, putative | 0.1055 | 1 | 1 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin B-like cysteine peptidase | 0.0195 | 0.1668 | 0.1479 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.1055 | 1 | 1 |
Brugia malayi | Cathepsin L-like precursor | 0.1055 | 1 | 1 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0195 | 0.1668 | 0.1479 |
Leishmania major | cathepsin L-like protease | 0.1055 | 1 | 1 |
Trypanosoma cruzi | cysteine protease, putative | 0.0544 | 0.5046 | 0.469 |
Plasmodium vivax | unspecified product | 0.0544 | 0.5046 | 0.4054 |
Echinococcus multilocularis | cathepsin L cysteine protease | 0.1055 | 1 | 1 |
Echinococcus multilocularis | cathepsin l cysteine peptidase | 0.1055 | 1 | 1 |
Giardia lamblia | Cathepsin B precursor | 0.0195 | 0.1668 | 1 |
Trypanosoma cruzi | cysteine peptidase (N-terminal), putative | 0.0544 | 0.5046 | 0.469 |
Schistosoma mansoni | cathepsin B-like peptidase (C01 family) | 0.0195 | 0.1668 | 0.1668 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0544 | 0.5046 | 0.4933 |
Loa Loa (eye worm) | hypothetical protein | 0.0706 | 0.6622 | 0.6569 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin B-like cysteine peptidase | 0.0195 | 0.1668 | 0.1479 |
Schistosoma mansoni | cathepsin B-like peptidase (C01 family) | 0.0195 | 0.1668 | 0.1668 |
Loa Loa (eye worm) | hypothetical protein | 0.0706 | 0.6622 | 0.6569 |
Entamoeba histolytica | cysteine protease, putative | 0.0544 | 0.5046 | 0.469 |
Giardia lamblia | Encystation-specific protease | 0.0195 | 0.1668 | 1 |
Loa Loa (eye worm) | papain family cysteine protease containing protein | 0.0195 | 0.1668 | 0.1538 |
Trichomonas vaginalis | CAMK family protein kinase | 0.0092 | 0.067 | 0.0458 |
Entamoeba histolytica | cysteine protease, putative | 0.0195 | 0.1668 | 0.107 |
Brugia malayi | cathepsin L-like cysteine proteinase | 0.0195 | 0.1668 | 0.1648 |
Loa Loa (eye worm) | hypothetical protein | 0.0195 | 0.1668 | 0.1538 |
Schistosoma mansoni | cathepsin F (C01 family) | 0.0706 | 0.6622 | 0.6622 |
Onchocerca volvulus | 0.1055 | 1 | 1 | |
Brugia malayi | cathepsin L-like precursor | 0.0706 | 0.6622 | 0.6614 |
Schistosoma mansoni | cathepsin B-like peptidase (C01 family) | 0.0195 | 0.1668 | 0.1668 |
Schistosoma mansoni | SmCL2-like peptidase (C01 family) | 0.0544 | 0.5046 | 0.5046 |
Echinococcus granulosus | cathepsin l cysteine peptidase | 0.1055 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0071 | 0.0466 | 0.0318 |
Giardia lamblia | Cathepsin L precursor | 0.0195 | 0.1668 | 1 |
Onchocerca volvulus | 0.1055 | 1 | 1 | |
Brugia malayi | Cathepsin L-like cysteine proteinase | 0.0706 | 0.6622 | 0.6614 |
Echinococcus multilocularis | bromodomain adjacent to zinc finger domain | 0.0036 | 0.013 | 0.013 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.1055 | 1 | 1 |
Loa Loa (eye worm) | Papain cysteine protease/cathepsin propeptide inhibitor-containing protein | 0.1055 | 1 | 1 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.1055 | 1 | 1 |
Entamoeba histolytica | papain family cysteine protease domain containing protein | 0.0195 | 0.1668 | 0.107 |
Trypanosoma cruzi | cysteine peptidase, clan CA, family C1, cathepsin L-like, putative | 0.0706 | 0.6622 | 0.638 |
Schistosoma mansoni | cathepsin S (C01 family) | 0.0195 | 0.1668 | 0.1668 |
Giardia lamblia | Cysteine protease | 0.0195 | 0.1668 | 1 |
Entamoeba histolytica | hypothetical protein | 0.0195 | 0.1668 | 0.107 |
Brugia malayi | Bromodomain containing protein | 0.0075 | 0.0507 | 0.0486 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.1055 | 1 | 1 |
Trypanosoma cruzi | cysteine peptidase C (CPC), putative | 0.0195 | 0.1668 | 0.107 |
Loa Loa (eye worm) | fibroinase | 0.1055 | 1 | 1 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.1055 | 1 | 1 |
Echinococcus multilocularis | cathepsin L | 0.0544 | 0.5046 | 0.5046 |
Loa Loa (eye worm) | hypothetical protein | 0.0195 | 0.1668 | 0.1538 |
Entamoeba histolytica | cysteine protease, putative | 0.0544 | 0.5046 | 0.469 |
Plasmodium vivax | vivapain-3 | 0.0544 | 0.5046 | 0.4054 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.1055 | 1 | 1 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0195 | 0.1668 | 0.1479 |
Echinococcus multilocularis | cathepsin L | 0.0195 | 0.1668 | 0.1668 |
Entamoeba histolytica | cysteine protease, putative | 0.0544 | 0.5046 | 0.469 |
Schistosoma mansoni | cathepsin B-like peptidase (C01 family) | 0.0195 | 0.1668 | 0.1668 |
Echinococcus multilocularis | cysteine protease | 0.1055 | 1 | 1 |
Brugia malayi | cathepsin Z-like cysteine proteinase | 0.0195 | 0.1668 | 0.1648 |
Schistosoma mansoni | dipeptidyl-peptidase I (C01 family) | 0.0195 | 0.1668 | 0.1668 |
Schistosoma mansoni | cathepsin F (C01 family) | 0.1055 | 1 | 1 |
Echinococcus granulosus | cysteine protease | 0.0544 | 0.5046 | 0.5046 |
Giardia lamblia | Cathepsin B precursor | 0.0195 | 0.1668 | 1 |
Giardia lamblia | Cathepsin L precursor | 0.0195 | 0.1668 | 1 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0706 | 0.6622 | 0.6546 |
Giardia lamblia | Cathepsin L precursor | 0.0195 | 0.1668 | 1 |
Entamoeba histolytica | cysteine protease, putative | 0.0544 | 0.5046 | 0.469 |
Entamoeba histolytica | cysteine protease, putative | 0.0544 | 0.5046 | 0.469 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.1055 | 1 | 1 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.1055 | 1 | 1 |
Brugia malayi | cathepsin L precursor | 0.0195 | 0.1668 | 0.1648 |
Trypanosoma cruzi | major cysteine proteinase, putative | 0.0195 | 0.1668 | 0.107 |
Echinococcus granulosus | geminin | 0.0334 | 0.3014 | 0.3014 |
Brugia malayi | Bromodomain containing protein | 0.0038 | 0.0152 | 0.013 |
Brugia malayi | cathepsin B-like cysteine proteinase | 0.0195 | 0.1668 | 0.1648 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.1055 | 1 | 1 |
Giardia lamblia | Cathepsin B precursor | 0.0195 | 0.1668 | 1 |
Leishmania major | cathepsin L-like protease | 0.1055 | 1 | 1 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0195 | 0.1668 | 0.1479 |
Entamoeba histolytica | cysteine protease, putative | 0.0195 | 0.1668 | 0.107 |
Giardia lamblia | Cysteine protease | 0.0195 | 0.1668 | 1 |
Schistosoma mansoni | cathepsin F (C01 family) | 0.1055 | 1 | 1 |
Entamoeba histolytica | cysteine proteinase, putative | 0.0544 | 0.5046 | 0.469 |
Trypanosoma cruzi | cruzipain precursor, putative | 0.1055 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0349 | 0.316 | 0.3054 |
Echinococcus granulosus | cathepsin L cysteine protease | 0.0544 | 0.5046 | 0.5046 |
Giardia lamblia | Cathepsin B precursor | 0.0195 | 0.1668 | 1 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0195 | 0.1668 | 0.1479 |
Brugia malayi | cathepsin Z-like cysteine proteinase | 0.0195 | 0.1668 | 0.1648 |
Echinococcus granulosus | serine:threonine protein kinase PLK1 | 0.0092 | 0.067 | 0.067 |
Entamoeba histolytica | cysteine protease, putative | 0.0544 | 0.5046 | 0.469 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0544 | 0.5046 | 0.469 |
Echinococcus granulosus | cathepsin L | 0.0195 | 0.1668 | 0.1668 |
Loa Loa (eye worm) | hypothetical protein | 0.0195 | 0.1668 | 0.1538 |
Echinococcus granulosus | cathepsin b | 0.0195 | 0.1668 | 0.1668 |
Schistosoma mansoni | subfamily C1A unassigned peptidase (C01 family) | 0.0195 | 0.1668 | 0.1668 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L, S or H-like cysteine peptidase | 0.0195 | 0.1668 | 0.1479 |
Giardia lamblia | Hypothetical protein | 0.0195 | 0.1668 | 1 |
Giardia lamblia | Dipeptidyl-peptidase I precursor | 0.0195 | 0.1668 | 1 |
Giardia lamblia | Cysteine protease | 0.0195 | 0.1668 | 1 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.1055 | 1 | 1 |
Onchocerca volvulus | 0.1055 | 1 | 1 | |
Schistosoma mansoni | serine/threonine protein kinase | 0.0092 | 0.067 | 0.067 |
Trichomonas vaginalis | CAMK family protein kinase | 0.0092 | 0.067 | 0.0458 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.1055 | 1 | 1 |
Schistosoma mansoni | hypothetical protein | 0.0334 | 0.3014 | 0.3014 |
Giardia lamblia | Dipeptidyl-peptidase I precursor | 0.0195 | 0.1668 | 1 |
Trypanosoma cruzi | cysteine proteinase, putative | 0.0544 | 0.5046 | 0.469 |
Brugia malayi | Papain family cysteine protease containing protein | 0.0195 | 0.1668 | 0.1648 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0544 | 0.5046 | 0.469 |
Entamoeba histolytica | cysteine proteinase, putative | 0.0544 | 0.5046 | 0.469 |
Schistosoma mansoni | cathepsin s | 0.0349 | 0.316 | 0.316 |
Loa Loa (eye worm) | ctsf protein | 0.1055 | 1 | 1 |
Echinococcus multilocularis | cysteine protease | 0.1055 | 1 | 1 |
Toxoplasma gondii | cathepsin CPL | 0.1055 | 1 | 1 |
Leishmania major | cathepsin L-like protease | 0.1055 | 1 | 1 |
Loa Loa (eye worm) | cysteine protease | 0.1055 | 1 | 1 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin H-like cysteine peptidase | 0.0195 | 0.1668 | 0.1479 |
Loa Loa (eye worm) | cathepsin B | 0.0195 | 0.1668 | 0.1538 |
Leishmania major | cathepsin L-like protease | 0.1055 | 1 | 1 |
Echinococcus multilocularis | cathepsin b | 0.0195 | 0.1668 | 0.1668 |
Loa Loa (eye worm) | hypothetical protein | 0.0349 | 0.316 | 0.3054 |
Schistosoma mansoni | SmCB2 peptidase (C01 family) | 0.0195 | 0.1668 | 0.1668 |
Echinococcus granulosus | cathepsin L cysteine proteinase | 0.1055 | 1 | 1 |
Trypanosoma cruzi | cysteine peptidase, putative | 0.1055 | 1 | 1 |
Trypanosoma cruzi | cruzipain precursor, putative | 0.0349 | 0.316 | 0.2669 |
Brugia malayi | Papain family cysteine protease containing protein | 0.0544 | 0.5046 | 0.5034 |
Schistosoma mansoni | subfamily C1A unassigned peptidase (C01 family) | 0.0195 | 0.1668 | 0.1668 |
Brugia malayi | cathepsin F-like cysteine proteinase | 0.0349 | 0.316 | 0.3144 |
Schistosoma mansoni | cathepsin B (C01 family) | 0.0195 | 0.1668 | 0.1668 |
Giardia lamblia | Cathepsin L-like protease | 0.0195 | 0.1668 | 1 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.1055 | 1 | 1 |
Echinococcus multilocularis | cathepsin b | 0.0195 | 0.1668 | 0.1668 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin B-like cysteine peptidase | 0.0195 | 0.1668 | 0.1479 |
Activity type | Activity value | Assay description | Source | Reference |
---|---|---|---|---|
IC50 (binding) | = 32 uM | Inhibition of Rev binding to Rev response element RNA in absence of competitor RNA | ChEMBL. | 16875816 |
IC50 (binding) | = 45 uM | Inhibition of Rev binding to Rev response element RNA in presence of competitor RNA | ChEMBL. | 16875816 |
Kd (binding) | = 0.03 uM | Binding affinity to Rev response element RNA | ChEMBL. | 16875816 |
Kd (binding) | = 0.21 uM | Binding affinity to tRNA | ChEMBL. | 16875816 |
Ratio (binding) | = 1.4 | Ratio of inhibition of Rev binding to Rev response element RNA in presence to absence of competitor RNA | ChEMBL. | 16875816 |
Ratio (binding) | = 7 | Discrimination factor, Kd for tRNA/Kd for Rev response element RNA | ChEMBL. | 16875816 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.
1 literature reference was collected for this gene.