Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Echinococcus multilocularis | rhodopsin orphan GPCR | 0.0266 | 0.313 | 0.313 |
Loa Loa (eye worm) | hypothetical protein | 0.0266 | 0.313 | 0.8146 |
Schistosoma mansoni | opsin-like receptor | 0.0266 | 0.313 | 0.9997 |
Trypanosoma cruzi | glyceraldehyde 3-phosphate dehydrogenase, putative | 0.0266 | 0.3131 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0266 | 0.313 | 0.8146 |
Loa Loa (eye worm) | hypothetical protein | 0.0171 | 0.1873 | 0.4875 |
Echinococcus granulosus | hypothetical protein | 0.0266 | 0.313 | 0.7791 |
Loa Loa (eye worm) | RNA binding protein | 0.0064 | 0.046 | 0.1198 |
Loa Loa (eye worm) | hypothetical protein | 0.0056 | 0.0351 | 0.0915 |
Echinococcus granulosus | rhodopsin orphan GPCR | 0.0266 | 0.313 | 0.7791 |
Onchocerca volvulus | 0.0266 | 0.313 | 0.8146 | |
Onchocerca volvulus | 0.0266 | 0.313 | 0.8146 | |
Entamoeba histolytica | glyceraldehyde-3-phosphate dehydrogenase, putative | 0.0266 | 0.3131 | 0.7963 |
Brugia malayi | Dopamine receptor protein 1 | 0.0266 | 0.313 | 0.8146 |
Onchocerca volvulus | 0.0266 | 0.313 | 0.8146 | |
Schistosoma mansoni | amine GPCR | 0.0266 | 0.313 | 0.9997 |
Brugia malayi | hypothetical protein | 0.0266 | 0.313 | 0.8146 |
Schistosoma mansoni | peptide (FMRFamide/neurokinin-3)-like receptor | 0.0266 | 0.313 | 0.9997 |
Trypanosoma cruzi | tyrosyl-DNA Phosphodiesterase (Tdp1), putative | 0.0065 | 0.0477 | 0.0453 |
Brugia malayi | hypothetical protein | 0.0266 | 0.313 | 0.8146 |
Schistosoma mansoni | equilibrative nucleoside transporter | 0.0056 | 0.0351 | 0.1122 |
Brugia malayi | hypothetical protein | 0.032 | 0.3843 | 1 |
Loa Loa (eye worm) | G-protein coupled receptor | 0.0266 | 0.313 | 0.8146 |
Leishmania major | glyceraldehyde 3-phosphate dehydrogenase, glycosomal | 0.0266 | 0.3131 | 1 |
Loa Loa (eye worm) | neuropeptide F receptor | 0.0266 | 0.313 | 0.8146 |
Trypanosoma cruzi | glyceraldehyde 3-phosphate dehydrogenase, putative | 0.0266 | 0.3131 | 1 |
Echinococcus granulosus | tar DNA binding protein | 0.0064 | 0.046 | 0.1145 |
Trypanosoma brucei | glyceraldehyde 3-phosphate dehydrogenase, glycosomal | 0.0266 | 0.3131 | 1 |
Echinococcus multilocularis | thyrotropin releasing hormone receptor | 0.0266 | 0.313 | 0.313 |
Echinococcus multilocularis | neuropeptide Y receptor | 0.0266 | 0.313 | 0.313 |
Loa Loa (eye worm) | hypothetical protein | 0.0266 | 0.313 | 0.8146 |
Echinococcus granulosus | fmrfamide receptor | 0.0266 | 0.313 | 0.7791 |
Mycobacterium ulcerans | glyceraldehyde 3-phosphate dehydrogenase Gap | 0.0266 | 0.3131 | 0.5 |
Schistosoma mansoni | peptide (allatostatin)-like receptor | 0.0266 | 0.313 | 0.9997 |
Loa Loa (eye worm) | TAR-binding protein | 0.0064 | 0.046 | 0.1198 |
Echinococcus granulosus | adenosine kinase | 0.0171 | 0.1873 | 0.4662 |
Schistosoma mansoni | tar DNA-binding protein | 0.0064 | 0.046 | 0.147 |
Brugia malayi | ORL1-like opioid receptor | 0.0266 | 0.313 | 0.8146 |
Schistosoma mansoni | amine GPCR | 0.0266 | 0.313 | 0.9997 |
Schistosoma mansoni | hypothetical protein | 0.0266 | 0.313 | 0.9997 |
Loa Loa (eye worm) | pre-SET domain-containing protein family protein | 0.0202 | 0.2282 | 0.594 |
Echinococcus multilocularis | glyceraldehyde 3 phosphate dehydrogenase | 0.0174 | 0.192 | 0.192 |
Toxoplasma gondii | glyceraldehyde-3-phosphate dehydrogenase GAPDH1 | 0.0266 | 0.3131 | 1 |
Brugia malayi | glyceraldehyde 3-phosphate dehydrogenase | 0.0082 | 0.0706 | 0.1838 |
Echinococcus granulosus | growth hormone secretagogue receptor type 1 | 0.0266 | 0.313 | 0.7791 |
Echinococcus multilocularis | 7TM GPCR, rhodopsin | 0.0266 | 0.313 | 0.313 |
Echinococcus granulosus | transcription factor Dp 1 | 0.0038 | 0.0115 | 0.0287 |
Echinococcus multilocularis | rhodopsin orphan GPCR | 0.0266 | 0.313 | 0.313 |
Trypanosoma cruzi | glyceraldehyde 3-phosphate dehydrogenase, cytosolic, putative | 0.0266 | 0.3131 | 1 |
Echinococcus multilocularis | tm gpcr rhodopsin gpcr rhodopsin superfamily | 0.0266 | 0.313 | 0.313 |
Loa Loa (eye worm) | hypothetical protein | 0.0266 | 0.313 | 0.8146 |
Loa Loa (eye worm) | glyceraldehyde-3-phosphate dehydrogenase | 0.0184 | 0.2043 | 0.5316 |
Onchocerca volvulus | 0.0266 | 0.313 | 0.8146 | |
Schistosoma mansoni | rhodopsin-like orphan GPCR | 0.0266 | 0.313 | 0.9997 |
Schistosoma mansoni | peptide (FMRFamide/somatostatin)-like receptor | 0.0266 | 0.313 | 0.9997 |
Trypanosoma cruzi | adenosine kinase, putative | 0.0171 | 0.1873 | 0.5474 |
Brugia malayi | G-protein-linked acetylcholine receptor protein 2, putative | 0.0266 | 0.313 | 0.8146 |
Echinococcus multilocularis | neuropeptide Y receptor | 0.0266 | 0.313 | 0.313 |
Loa Loa (eye worm) | hypothetical protein | 0.0266 | 0.313 | 0.8146 |
Schistosoma mansoni | hypothetical protein | 0.0266 | 0.313 | 0.9997 |
Echinococcus multilocularis | g protein linked acetylcholine receptor gar 2a | 0.0266 | 0.313 | 0.313 |
Echinococcus granulosus | glyceraldehyde 3 phosphate dehydrogenase | 0.0266 | 0.3131 | 0.7793 |
Onchocerca volvulus | 0.0049 | 0.0262 | 0.0681 | |
Echinococcus granulosus | somatostatin receptor | 0.0266 | 0.313 | 0.7791 |
Loa Loa (eye worm) | hypothetical protein | 0.0266 | 0.313 | 0.8146 |
Echinococcus multilocularis | fmrfamide receptor | 0.0266 | 0.313 | 0.313 |
Onchocerca volvulus | 0.0266 | 0.313 | 0.8146 | |
Brugia malayi | hypothetical protein | 0.0266 | 0.313 | 0.8146 |
Loa Loa (eye worm) | hypothetical protein | 0.0266 | 0.313 | 0.8146 |
Echinococcus multilocularis | tumor protein p63 | 0.0333 | 0.4018 | 0.4018 |
Echinococcus granulosus | rhodopsin orphan GPCR | 0.0266 | 0.313 | 0.7791 |
Onchocerca volvulus | 0.0266 | 0.313 | 0.8146 | |
Brugia malayi | Melatonin receptor type 1A | 0.0266 | 0.313 | 0.8146 |
Echinococcus multilocularis | transcription factor Dp 1 | 0.0038 | 0.0115 | 0.0115 |
Echinococcus multilocularis | g-protein coupled receptor | 0.0266 | 0.313 | 0.313 |
Loa Loa (eye worm) | hypothetical protein | 0.0266 | 0.313 | 0.8146 |
Brugia malayi | hypothetical protein | 0.0266 | 0.313 | 0.8146 |
Echinococcus multilocularis | rhodopsin orphan GPCR | 0.0266 | 0.313 | 0.313 |
Brugia malayi | G-protein coupled receptor | 0.0266 | 0.313 | 0.8146 |
Echinococcus granulosus | glyceraldehyde 3 phosphate dehydrogenase | 0.0174 | 0.192 | 0.4778 |
Echinococcus multilocularis | rhodopsin orphan GPCR | 0.0266 | 0.313 | 0.313 |
Brugia malayi | gonadotropin-releasing hormone receptor 2 | 0.0266 | 0.313 | 0.8146 |
Echinococcus multilocularis | fmrfamide receptor | 0.0266 | 0.313 | 0.313 |
Echinococcus multilocularis | allatostatin A receptor | 0.0266 | 0.313 | 0.313 |
Brugia malayi | putative neuropeptide receptor NPR1 | 0.0266 | 0.313 | 0.8146 |
Schistosoma mansoni | hypothetical protein | 0.0266 | 0.313 | 0.9997 |
Brugia malayi | hypothetical protein | 0.0266 | 0.313 | 0.8146 |
Echinococcus granulosus | rhodopsin orphan GPCR | 0.0266 | 0.313 | 0.7791 |
Trypanosoma cruzi | glyceraldehyde 3-phosphate dehydrogenase, C-terminal domain, putative | 0.0082 | 0.0706 | 0.1276 |
Brugia malayi | Dopamine receptor protein 2 | 0.0266 | 0.313 | 0.8146 |
Echinococcus multilocularis | neuropeptide receptor A26 | 0.0266 | 0.313 | 0.313 |
Echinococcus multilocularis | peptide (allatostatin:somatostatin) | 0.0266 | 0.313 | 0.313 |
Schistosoma mansoni | rhodopsin-like orphan GPCR | 0.0266 | 0.313 | 0.9997 |
Echinococcus granulosus | G protein coupled 5 hydroxytryptamine receptor | 0.0266 | 0.313 | 0.7791 |
Loa Loa (eye worm) | glyceraldehyde-3-phosphate dehydrogenase | 0.0184 | 0.2043 | 0.5316 |
Schistosoma mansoni | neuropeptide F-like receptor | 0.0266 | 0.313 | 0.9997 |
Loa Loa (eye worm) | hypothetical protein | 0.0266 | 0.313 | 0.8146 |
Treponema pallidum | glyceraldehyde 3-phosphate dehydrogenase (gap) | 0.0266 | 0.3131 | 0.5 |
Echinococcus multilocularis | serotonin receptor | 0.0266 | 0.313 | 0.313 |
Brugia malayi | RNA binding protein | 0.0064 | 0.046 | 0.1198 |
Loa Loa (eye worm) | hypothetical protein | 0.0266 | 0.313 | 0.8146 |
Schistosoma mansoni | biogenic amine receptor | 0.0266 | 0.313 | 0.9997 |
Schistosoma mansoni | peptide (allatostatin/somatostatin)-like receptor | 0.0266 | 0.313 | 0.9997 |
Echinococcus multilocularis | sex peptide receptor | 0.0266 | 0.313 | 0.313 |
Brugia malayi | RE15519p | 0.0266 | 0.313 | 0.8146 |
Schistosoma mansoni | rhodopsin-like orphan GPCR | 0.0266 | 0.313 | 0.9997 |
Schistosoma mansoni | rhodopsin-like orphan GPCR | 0.0266 | 0.313 | 0.9997 |
Echinococcus granulosus | dro:myosuppressin receptor | 0.0266 | 0.313 | 0.7791 |
Chlamydia trachomatis | glyceraldehyde-3-phosphate dehydrogenase | 0.0266 | 0.3131 | 0.5 |
Echinococcus granulosus | thyrotropin releasing hormone receptor | 0.0266 | 0.313 | 0.7791 |
Echinococcus multilocularis | rhodopsin orphan GPCR | 0.0266 | 0.313 | 0.313 |
Echinococcus multilocularis | equilibrative nucleoside transporter 3 | 0.032 | 0.3843 | 0.3843 |
Loa Loa (eye worm) | hypothetical protein | 0.0266 | 0.313 | 0.8146 |
Echinococcus multilocularis | glyceraldehyde 3 phosphate dehydrogenase | 0.0266 | 0.3131 | 0.3131 |
Trypanosoma cruzi | glyceraldehyde 3-phosphate dehydrogenase, C-terminal domain, putative | 0.0082 | 0.0706 | 0.1276 |
Leishmania major | glyceraldehyde 3-phosphate dehydrogenase, glycosomal | 0.0266 | 0.3131 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0266 | 0.313 | 0.8146 |
Plasmodium falciparum | glyceraldehyde-3-phosphate dehydrogenase | 0.0266 | 0.3131 | 0.5 |
Loa Loa (eye worm) | hypothetical protein | 0.0266 | 0.313 | 0.8146 |
Loa Loa (eye worm) | hypothetical protein | 0.0266 | 0.313 | 0.8146 |
Echinococcus granulosus | G protein coupled receptor 139 | 0.0266 | 0.313 | 0.7791 |
Onchocerca volvulus | 0.0266 | 0.313 | 0.8146 | |
Schistosoma mansoni | tar DNA-binding protein | 0.0064 | 0.046 | 0.147 |
Loa Loa (eye worm) | hypothetical protein | 0.0266 | 0.313 | 0.8146 |
Brugia malayi | AKH receptor | 0.0266 | 0.313 | 0.8146 |
Echinococcus multilocularis | g protein coupled receptor | 0.0266 | 0.313 | 0.313 |
Trypanosoma cruzi | glyceraldehyde 3-phosphate dehydrogenase, putative | 0.0266 | 0.3131 | 1 |
Schistosoma mansoni | hypothetical protein | 0.0266 | 0.313 | 0.9997 |
Schistosoma mansoni | opsin-like receptor | 0.0266 | 0.313 | 0.9997 |
Echinococcus multilocularis | dro:myosuppressin receptor | 0.0266 | 0.313 | 0.313 |
Loa Loa (eye worm) | hypothetical protein | 0.0266 | 0.313 | 0.8146 |
Brugia malayi | Pre-SET motif family protein | 0.0202 | 0.2282 | 0.594 |
Loa Loa (eye worm) | RNA recognition domain-containing protein domain-containing protein | 0.0064 | 0.046 | 0.1198 |
Loa Loa (eye worm) | hypothetical protein | 0.0266 | 0.313 | 0.8146 |
Echinococcus granulosus | 7tm_1 domain containing protein | 0.0266 | 0.313 | 0.7791 |
Schistosoma mansoni | amine GPCR | 0.0266 | 0.313 | 0.9997 |
Echinococcus granulosus | neuropeptides capa receptor | 0.0266 | 0.313 | 0.7791 |
Loa Loa (eye worm) | hypothetical protein | 0.0266 | 0.313 | 0.8146 |
Onchocerca volvulus | 0.0266 | 0.313 | 0.8146 | |
Onchocerca volvulus | 0.0266 | 0.313 | 0.8146 | |
Toxoplasma gondii | nucleoside transporter protein | 0.0056 | 0.0351 | 0.1122 |
Loa Loa (eye worm) | follicle stimulating hormone receptor | 0.0266 | 0.313 | 0.8146 |
Brugia malayi | sulfakinin receptor protein | 0.0266 | 0.313 | 0.8146 |
Trypanosoma cruzi | glyceraldehyde 3-phosphate dehydrogenase, cytosolic, putative | 0.0266 | 0.3131 | 1 |
Loa Loa (eye worm) | unidentified vitellogenin-linked transcript protein 6 | 0.0266 | 0.313 | 0.8146 |
Echinococcus granulosus | g protein coupled receptor | 0.0266 | 0.313 | 0.7791 |
Loa Loa (eye worm) | hypothetical protein | 0.0266 | 0.313 | 0.8146 |
Echinococcus granulosus | neuropeptides capa receptor | 0.0266 | 0.313 | 0.7791 |
Echinococcus multilocularis | tm gpcr rhodopsin gpcr rhodopsin superfamily | 0.0266 | 0.313 | 0.313 |
Loa Loa (eye worm) | hypothetical protein | 0.0266 | 0.313 | 0.8146 |
Echinococcus granulosus | glyceraldehyde 3 phosphate dehydrogenase | 0.0266 | 0.3131 | 0.7793 |
Loa Loa (eye worm) | hypothetical protein | 0.0266 | 0.313 | 0.8146 |
Loa Loa (eye worm) | hypothetical protein | 0.0266 | 0.313 | 0.8146 |
Echinococcus granulosus | neuropeptide receptor | 0.0266 | 0.313 | 0.7791 |
Leishmania major | adenosine kinase, putative | 0.0171 | 0.1873 | 0.5474 |
Schistosoma mansoni | myosin xvIII | 0.0266 | 0.313 | 0.9997 |
Echinococcus multilocularis | tyrosyl DNA phosphodiesterase 1 | 0.0065 | 0.0477 | 0.0477 |
Onchocerca volvulus | 0.0266 | 0.313 | 0.8146 | |
Schistosoma mansoni | histamine h1 receptor | 0.0266 | 0.313 | 0.9997 |
Onchocerca volvulus | 0.0266 | 0.313 | 0.8146 | |
Brugia malayi | hypothetical protein | 0.0266 | 0.313 | 0.8146 |
Schistosoma mansoni | glyceraldehyde-3-phosphate dehydrogenase (phosphorylating) | 0.0266 | 0.3131 | 1 |
Schistosoma mansoni | neuropeptide F-like receptor | 0.0266 | 0.313 | 0.9997 |
Echinococcus granulosus | tm gpcr rhodopsin | 0.0266 | 0.313 | 0.7791 |
Schistosoma mansoni | neuropeptide f receptor 76f | 0.0266 | 0.313 | 0.9997 |
Echinococcus multilocularis | rhodopsin orphan GPCR | 0.0266 | 0.313 | 0.313 |
Trichomonas vaginalis | glyceraldehyde 3-phosphate dehydrogenase, putative | 0.0174 | 0.192 | 0.4492 |
Loa Loa (eye worm) | hypothetical protein | 0.0174 | 0.192 | 0.4996 |
Brugia malayi | TAR-binding protein | 0.0064 | 0.046 | 0.1198 |
Schistosoma mansoni | biogenic amine (octopamine/dopamine) receptor | 0.0266 | 0.313 | 0.9997 |
Entamoeba histolytica | tyrosyl-DNA phosphodiesterase, putative | 0.0065 | 0.0477 | 0.0361 |
Brugia malayi | Serotonin receptor | 0.0266 | 0.313 | 0.8146 |
Brugia malayi | Tachykinin-like peptides receptor 99D | 0.0266 | 0.313 | 0.8146 |
Onchocerca volvulus | Dopamine\/Ecdysteroid receptor homolog | 0.0266 | 0.313 | 0.8146 |
Brugia malayi | RNA recognition motif domain containing protein | 0.0064 | 0.046 | 0.1198 |
Echinococcus multilocularis | G-protein coupled receptor, putative | 0.0266 | 0.313 | 0.313 |
Schistosoma mansoni | neuropeptide receptor | 0.0266 | 0.313 | 0.9997 |
Mycobacterium tuberculosis | Probable glyceraldehyde 3-phosphate dehydrogenase Gap (GAPDH) | 0.0092 | 0.0831 | 0.5 |
Loa Loa (eye worm) | hypothetical protein | 0.0266 | 0.313 | 0.8146 |
Echinococcus granulosus | neuropeptide s receptor | 0.0266 | 0.313 | 0.7791 |
Trypanosoma cruzi | glyceraldehyde 3-phosphate dehydrogenase, putative | 0.0082 | 0.0706 | 0.1276 |
Trypanosoma cruzi | glyceraldehyde 3-phosphate dehydrogenase, cytosolic, putative | 0.0266 | 0.3131 | 1 |
Onchocerca volvulus | Equilibrative nucleoside transporter, putative homolog | 0.032 | 0.3843 | 1 |
Echinococcus granulosus | equilibrative nucleoside transporter 3 | 0.032 | 0.3843 | 0.9563 |
Echinococcus multilocularis | tm gpcr rhodopsin gpcr rhodopsin superfamily | 0.0266 | 0.313 | 0.313 |
Echinococcus multilocularis | g protein linked acetylcholine receptor gar 2a | 0.0266 | 0.313 | 0.313 |
Trichomonas vaginalis | glyceraldehyde 3-phosphate dehydrogenase, putative | 0.0092 | 0.0829 | 0.1369 |
Trypanosoma cruzi | glyceraldehyde 3-phosphate dehydrogenase, cytosolic, putative | 0.0082 | 0.0706 | 0.1276 |
Echinococcus granulosus | tm gpcr rhodopsin | 0.0266 | 0.313 | 0.7791 |
Onchocerca volvulus | 0.023 | 0.2651 | 0.6898 | |
Schistosoma mansoni | glyceraldehyde-3-phosphate dehydrogenase (phosphorylating) | 0.0266 | 0.3131 | 1 |
Brugia malayi | neuropeptide F receptor | 0.0266 | 0.313 | 0.8146 |
Schistosoma mansoni | amine GPCR | 0.0266 | 0.313 | 0.9997 |
Schistosoma mansoni | tar DNA-binding protein | 0.0064 | 0.046 | 0.147 |
Brugia malayi | Unidentified vitellogenin-linked transcript protein 6, putative | 0.0266 | 0.313 | 0.8146 |
Schistosoma mansoni | histamine-responsive GPCR (AAF21638) | 0.0266 | 0.313 | 0.9997 |
Echinococcus granulosus | biogenic amine 5HT receptor | 0.0266 | 0.313 | 0.7791 |
Onchocerca volvulus | 0.0266 | 0.313 | 0.8146 | |
Schistosoma mansoni | tyrosyl-DNA phosphodiesterase | 0.0065 | 0.0477 | 0.1525 |
Loa Loa (eye worm) | hypothetical protein | 0.0266 | 0.313 | 0.8146 |
Trypanosoma brucei | glyceraldehyde-3-phosphate dehydrogenase, putative | 0.0174 | 0.1918 | 0.5635 |
Schistosoma mansoni | adenosine kinase | 0.0171 | 0.1873 | 0.5982 |
Loa Loa (eye worm) | tyrosyl-DNA phosphodiesterase | 0.0065 | 0.0477 | 0.1243 |
Echinococcus granulosus | tachykinin peptides receptor 99D | 0.0266 | 0.313 | 0.7791 |
Echinococcus multilocularis | G protein coupled receptor 139 | 0.0266 | 0.313 | 0.313 |
Loa Loa (eye worm) | hypothetical protein | 0.0266 | 0.313 | 0.8146 |
Brugia malayi | Dopamine receptor protein 1, putative (partial) | 0.0266 | 0.313 | 0.8146 |
Brugia malayi | Glyceraldehyde 3-phosphate dehydrogenase | 0.0266 | 0.3131 | 0.8149 |
Schistosoma mansoni | biogenic amine (5HT) receptor | 0.0266 | 0.313 | 0.9997 |
Loa Loa (eye worm) | hypothetical protein | 0.0266 | 0.313 | 0.8146 |
Loa Loa (eye worm) | hypothetical protein | 0.0266 | 0.313 | 0.8146 |
Trypanosoma cruzi | glyceraldehyde-3-phosphate dehydrogenase, putative | 0.0174 | 0.1918 | 0.5635 |
Echinococcus granulosus | tm gpcr rhodopsin | 0.0266 | 0.313 | 0.7791 |
Schistosoma mansoni | neuropeptide receptor | 0.0266 | 0.313 | 0.9997 |
Trichomonas vaginalis | glyceraldehyde 3-phosphate dehydrogenase, putative | 0.0174 | 0.192 | 0.4492 |
Echinococcus multilocularis | neuropeptide receptor | 0.0266 | 0.313 | 0.313 |
Onchocerca volvulus | 0.0266 | 0.313 | 0.8146 | |
Echinococcus multilocularis | neuropeptides capa receptor | 0.0266 | 0.313 | 0.313 |
Echinococcus multilocularis | tar DNA binding protein | 0.0064 | 0.046 | 0.046 |
Schistosoma mansoni | tar DNA-binding protein | 0.0064 | 0.046 | 0.147 |
Trypanosoma cruzi | tyrosyl-DNA Phosphodiesterase (Tdp1), putative | 0.0065 | 0.0477 | 0.0453 |
Schistosoma mansoni | biogenic amine (5HT) receptor | 0.0266 | 0.313 | 0.9997 |
Echinococcus granulosus | rhodopsin orphan GPCR | 0.0266 | 0.313 | 0.7791 |
Trichomonas vaginalis | glyceraldehyde 3-phosphate dehydrogenase, putative | 0.0266 | 0.3131 | 0.7963 |
Schistosoma mansoni | biogenic amine (dopamine) receptor | 0.0266 | 0.313 | 0.9997 |
Loa Loa (eye worm) | hypothetical protein | 0.0266 | 0.313 | 0.8146 |
Onchocerca volvulus | 0.0266 | 0.313 | 0.8146 | |
Brugia malayi | Serotonin receptor | 0.0266 | 0.313 | 0.8146 |
Echinococcus granulosus | tumor protein p63 | 0.0333 | 0.4018 | 1 |
Schistosoma mansoni | amine GPCR | 0.0266 | 0.313 | 0.9997 |
Echinococcus multilocularis | serotonin receptor | 0.0266 | 0.313 | 0.313 |
Trypanosoma cruzi | glyceraldehyde-3-phosphate dehydrogenase, putative | 0.0174 | 0.1918 | 0.5635 |
Echinococcus granulosus | rhodopsin orphan GPCR | 0.0266 | 0.313 | 0.7791 |
Loa Loa (eye worm) | 5-hydroxytryptamine 2C receptor | 0.0266 | 0.313 | 0.8146 |
Brugia malayi | Tyrosyl-DNA phosphodiesterase family protein | 0.0065 | 0.0477 | 0.1243 |
Trichomonas vaginalis | set domain proteins, putative | 0.023 | 0.2651 | 0.6585 |
Echinococcus granulosus | neuropeptide FF receptor 2 | 0.0266 | 0.313 | 0.7791 |
Echinococcus multilocularis | glyceraldehyde 3 phosphate dehydrogenase | 0.0266 | 0.3131 | 0.3131 |
Loa Loa (eye worm) | hypothetical protein | 0.0266 | 0.313 | 0.8146 |
Schistosoma mansoni | glyceraldehyde-3-phosphate dehydrogenase (phosphorylating) | 0.0266 | 0.3131 | 1 |
Echinococcus multilocularis | G protein coupled 5 hydroxytryptamine receptor | 0.0266 | 0.313 | 0.313 |
Echinococcus granulosus | equilibrative nucleoside transporter | 0.032 | 0.3843 | 0.9563 |
Echinococcus multilocularis | g protein coupled receptor | 0.0266 | 0.313 | 0.313 |
Schistosoma mansoni | rhodopsin-like orphan GPCR | 0.0266 | 0.313 | 0.9997 |
Onchocerca volvulus | Equilibrative nucleoside transporter, putative homolog | 0.032 | 0.3843 | 1 |
Echinococcus multilocularis | adenosine kinase | 0.0171 | 0.1873 | 0.1873 |
Echinococcus granulosus | sex peptide receptor | 0.0266 | 0.313 | 0.7791 |
Brugia malayi | putative neuropeptide receptor | 0.0266 | 0.313 | 0.8146 |
Echinococcus granulosus | 7TM GPCR rhodopsin | 0.0266 | 0.313 | 0.7791 |
Leishmania major | tyrosyl-DNA phosphodiesterase 1 | 0.0065 | 0.0477 | 0.0453 |
Trichomonas vaginalis | glyceraldehyde 3-phosphate dehydrogenase, putative | 0.0266 | 0.3131 | 0.7963 |
Loa Loa (eye worm) | hypothetical protein | 0.0266 | 0.313 | 0.8146 |
Schistosoma mansoni | opsin-like receptor | 0.0266 | 0.313 | 0.9997 |
Entamoeba histolytica | glyceraldehyde-3-phosphate dehydrogenase, putative | 0.0266 | 0.3131 | 0.7963 |
Echinococcus granulosus | orexin receptor type 2 | 0.0266 | 0.313 | 0.7791 |
Echinococcus multilocularis | g protein coupled receptor | 0.0266 | 0.313 | 0.313 |
Schistosoma mansoni | neuropeptide receptor | 0.0266 | 0.313 | 0.9997 |
Echinococcus multilocularis | rhodopsin orphan GPCR | 0.0266 | 0.313 | 0.313 |
Schistosoma mansoni | tar DNA-binding protein | 0.0064 | 0.046 | 0.147 |
Schistosoma mansoni | muscarinic acetylcholine (GAR) receptor | 0.0266 | 0.313 | 0.9997 |
Echinococcus multilocularis | tachykinin peptides receptor 99D | 0.0266 | 0.313 | 0.313 |
Loa Loa (eye worm) | TYRA-2 protein | 0.0266 | 0.313 | 0.8146 |
Echinococcus granulosus | g protein coupled receptor | 0.0266 | 0.313 | 0.7791 |
Brugia malayi | GnHR receptor homolog | 0.0266 | 0.313 | 0.8146 |
Loa Loa (eye worm) | hypothetical protein | 0.0266 | 0.313 | 0.8146 |
Schistosoma mansoni | rhodopsin-like orphan GPCR | 0.0266 | 0.313 | 0.9997 |
Schistosoma mansoni | rhodopsin-like orphan GPCR | 0.0266 | 0.313 | 0.9997 |
Schistosoma mansoni | rhodopsin-like orphan GPCR | 0.0266 | 0.313 | 0.9997 |
Schistosoma mansoni | biogenic amine (dopamine) receptor | 0.0266 | 0.313 | 0.9997 |
Echinococcus granulosus | neuropeptide receptor A26 | 0.0266 | 0.313 | 0.7791 |
Echinococcus multilocularis | somatostatin receptor | 0.0266 | 0.313 | 0.313 |
Echinococcus multilocularis | neuropeptide receptor | 0.0266 | 0.313 | 0.313 |
Giardia lamblia | Hypothetical protein | 0.032 | 0.3843 | 1 |
Schistosoma mansoni | adenosine kinase | 0.0171 | 0.1873 | 0.5982 |
Brugia malayi | G protein-coupled receptor F59B2.13 | 0.0266 | 0.313 | 0.8146 |
Onchocerca volvulus | 0.0151 | 0.1616 | 0.4206 | |
Loa Loa (eye worm) | hypothetical protein | 0.0266 | 0.313 | 0.8146 |
Schistosoma mansoni | adenoreceptor | 0.0266 | 0.313 | 0.9997 |
Loa Loa (eye worm) | hypothetical protein | 0.0266 | 0.313 | 0.8146 |
Echinococcus multilocularis | neuropeptide s receptor | 0.0266 | 0.313 | 0.313 |
Echinococcus multilocularis | alpha 1A adrenergic receptor | 0.0266 | 0.313 | 0.313 |
Brugia malayi | Serotonin/octopamine receptor family protein 7 | 0.0266 | 0.313 | 0.8146 |
Loa Loa (eye worm) | G-protein-linked acetylcholine receptor protein 2 | 0.0266 | 0.313 | 0.8146 |
Loa Loa (eye worm) | hypothetical protein | 0.0266 | 0.313 | 0.8146 |
Echinococcus granulosus | g-protein coupled receptor | 0.0266 | 0.313 | 0.7791 |
Brugia malayi | hypothetical protein | 0.0266 | 0.313 | 0.8146 |
Entamoeba histolytica | glyceraldehyde-3-phosphate dehydrogenase, putative | 0.0266 | 0.3131 | 0.7963 |
Trichomonas vaginalis | glyceraldehyde 3-phosphate dehydrogenase, putative | 0.0266 | 0.3131 | 0.7963 |
Echinococcus granulosus | neuropeptide Y receptor | 0.0266 | 0.313 | 0.7791 |
Loa Loa (eye worm) | hypothetical protein | 0.0266 | 0.313 | 0.8146 |
Brugia malayi | neuropeptide F receptor | 0.0266 | 0.313 | 0.8146 |
Echinococcus multilocularis | neuropeptide FF receptor 2 | 0.0266 | 0.313 | 0.313 |
Loa Loa (eye worm) | hypothetical protein | 0.0266 | 0.313 | 0.8146 |
Loa Loa (eye worm) | neuropeptide F receptor | 0.0266 | 0.313 | 0.8146 |
Loa Loa (eye worm) | glyceraldehyde 3-phosphate dehydrogenase | 0.0174 | 0.192 | 0.4996 |
Brugia malayi | G-protein coupled receptor | 0.0266 | 0.313 | 0.8146 |
Echinococcus granulosus | serotonin receptor | 0.0266 | 0.313 | 0.7791 |
Echinococcus granulosus | g protein linked acetylcholine receptor gar 2a | 0.0266 | 0.313 | 0.7791 |
Echinococcus granulosus | neuropeptide receptor | 0.0266 | 0.313 | 0.7791 |
Brugia malayi | Dopamine receptor | 0.0266 | 0.313 | 0.8146 |
Echinococcus granulosus | pyroglutamylated rfamide peptide receptor | 0.0266 | 0.313 | 0.7791 |
Loa Loa (eye worm) | hypothetical protein | 0.032 | 0.3843 | 1 |
Brugia malayi | follicle stimulating hormone receptor | 0.0266 | 0.313 | 0.8146 |
Schistosoma mansoni | growth hormone secretagogue receptor | 0.0266 | 0.313 | 0.9997 |
Schistosoma mansoni | ancient conserved domain protein 2 (cyclin m2) | 0.0266 | 0.313 | 0.9997 |
Loa Loa (eye worm) | hypothetical protein | 0.0266 | 0.313 | 0.8146 |
Echinococcus multilocularis | rhodopsin orphan GPCR | 0.0266 | 0.313 | 0.313 |
Echinococcus multilocularis | biogenic amine (5HT) receptor | 0.0266 | 0.313 | 0.313 |
Echinococcus granulosus | alpha 1A adrenergic receptor | 0.0266 | 0.313 | 0.7791 |
Schistosoma mansoni | neuropeptide receptor | 0.0266 | 0.313 | 0.9997 |
Schistosoma mansoni | biogenic amine receptor | 0.0266 | 0.313 | 0.9997 |
Echinococcus multilocularis | equilibrative nucleoside transporter 3 | 0.0264 | 0.3109 | 0.3109 |
Brugia malayi | Glyceraldehyde 3-phosphate dehydrogenase | 0.0092 | 0.0829 | 0.2158 |
Schistosoma mansoni | peptide (FMRFamide/somatostatin)-like receptor | 0.0266 | 0.313 | 0.9997 |
Echinococcus granulosus | tyrosyl DNA phosphodiesterase 1 | 0.0065 | 0.0477 | 0.1188 |
Loa Loa (eye worm) | hypothetical protein | 0.0266 | 0.313 | 0.8146 |
Onchocerca volvulus | 0.0266 | 0.313 | 0.8146 | |
Loa Loa (eye worm) | hypothetical protein | 0.0266 | 0.313 | 0.8146 |
Brugia malayi | Adenosine kinase-like | 0.0171 | 0.1873 | 0.4875 |
Loa Loa (eye worm) | hypothetical protein | 0.032 | 0.3843 | 1 |
Brugia malayi | hypothetical protein | 0.0056 | 0.0351 | 0.0915 |
Trypanosoma brucei | adenosine kinase, putative | 0.0171 | 0.1873 | 0.5474 |
Trypanosoma cruzi | glyceraldehyde 3-phosphate dehydrogenase, putative | 0.0266 | 0.3131 | 1 |
Loa Loa (eye worm) | glyceraldehyde 3-phosphate dehydrogenase | 0.0174 | 0.192 | 0.4996 |
Schistosoma mansoni | biogenic amine (dopamine) receptor | 0.0266 | 0.313 | 0.9997 |
Trichomonas vaginalis | equilibrative nucleoside transporter, putative | 0.032 | 0.3843 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0049 | 0.0262 | 0.0681 |
Schistosoma mansoni | thyrotropin-releasing hormone receptor | 0.0266 | 0.313 | 0.9997 |
Trichomonas vaginalis | equilibrative nucleoside transporter, putative | 0.032 | 0.3843 | 1 |
Trichomonas vaginalis | equilibrative nucleoside transporter, putative | 0.032 | 0.3843 | 1 |
Onchocerca volvulus | 0.0266 | 0.313 | 0.8146 | |
Echinococcus granulosus | allatostatin A receptor | 0.0266 | 0.313 | 0.7791 |
Brugia malayi | larval opioid receptor | 0.0266 | 0.313 | 0.8146 |
Plasmodium vivax | glyceraldehyde-3-phosphate dehydrogenase, putative | 0.0266 | 0.3131 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.032 | 0.3843 | 1 |
Giardia lamblia | Glyceraldehyde 3-phosphate dehydrogenase | 0.0266 | 0.3131 | 0.6305 |
Loa Loa (eye worm) | melatonin receptor type 1A | 0.0266 | 0.313 | 0.8146 |
Brugia malayi | Nucleoside transporter family protein | 0.032 | 0.3843 | 1 |
Trypanosoma cruzi | glyceraldehyde 3-phosphate dehydrogenase, cytosolic, putative | 0.0082 | 0.0706 | 0.1276 |
Trypanosoma brucei | glyceraldehyde 3-phosphate dehydrogenase, cytosolic | 0.0266 | 0.3131 | 1 |
Trypanosoma brucei | tyrosyl-DNA Phosphodiesterase (Tdp1), putative | 0.0065 | 0.0477 | 0.0453 |
Trypanosoma brucei | adenosine kinase, putative | 0.0171 | 0.1873 | 0.5474 |
Leishmania major | glyceraldehyde-3-phosphate dehydrogenase-like protein | 0.0174 | 0.1918 | 0.5635 |
Echinococcus granulosus | rhodopsin orphan GPCR | 0.0266 | 0.313 | 0.7791 |
Toxoplasma gondii | nucleoside transporter protein | 0.0056 | 0.0351 | 0.1122 |
Loa Loa (eye worm) | hypothetical protein | 0.0266 | 0.313 | 0.8146 |
Loa Loa (eye worm) | hypothetical protein | 0.0266 | 0.313 | 0.8146 |
Brugia malayi | hypothetical protein | 0.0266 | 0.313 | 0.8146 |
Onchocerca volvulus | Neuropeptide F receptor homolog | 0.0266 | 0.313 | 0.8146 |
Loa Loa (eye worm) | hypothetical protein | 0.0266 | 0.313 | 0.8146 |
Echinococcus multilocularis | neuropeptides capa receptor | 0.0266 | 0.313 | 0.313 |
Loa Loa (eye worm) | hypothetical protein | 0.0266 | 0.313 | 0.8146 |
Schistosoma mansoni | cellular tumor antigen P53 | 0.0049 | 0.0262 | 0.0836 |
Echinococcus granulosus | biogenic amine 5HT receptor | 0.0266 | 0.313 | 0.7791 |
Wolbachia endosymbiont of Brugia malayi | glyceraldehyde-3-phosphate dehydrogenase, GapA | 0.0266 | 0.3131 | 0.5 |
Loa Loa (eye worm) | hypothetical protein | 0.0266 | 0.313 | 0.8146 |
Echinococcus multilocularis | growth hormone secretagogue receptor type 1 | 0.0266 | 0.313 | 0.313 |
Schistosoma mansoni | glyceraldehyde-3-phosphate dehydrogenase (phosphorylating) | 0.0266 | 0.3131 | 1 |
Schistosoma mansoni | alpha-1 adrenergic receptor | 0.0266 | 0.313 | 0.9997 |
Trichomonas vaginalis | glyceraldehyde 3-phosphate dehydrogenase, putative | 0.0266 | 0.3131 | 0.7963 |
Trypanosoma cruzi | adenosine kinase, putative | 0.0171 | 0.1873 | 0.5474 |
Schistosoma mansoni | biogenic amine receptor | 0.0266 | 0.313 | 0.9997 |
Onchocerca volvulus | 0.0266 | 0.313 | 0.8146 | |
Loa Loa (eye worm) | gonadotropin-releasing hormone receptor 2 | 0.0266 | 0.313 | 0.8146 |
Echinococcus multilocularis | pyroglutamylated rfamide peptide receptor | 0.0266 | 0.313 | 0.313 |
Trypanosoma brucei | glyceraldehyde 3-phosphate dehydrogenase, glycosomal | 0.0266 | 0.3131 | 1 |
Echinococcus granulosus | neuropeptide Y receptor | 0.0266 | 0.313 | 0.7791 |
Mycobacterium leprae | Probable glyceraldehyde 3-phosphate dehydrogenase Gap (GAPDH) | 0.0092 | 0.0831 | 0.5 |
Schistosoma mansoni | rhodopsin-like orphan GPCR | 0.0266 | 0.313 | 0.9997 |
Brugia malayi | G protein-coupled receptor | 0.0266 | 0.313 | 0.8146 |
Entamoeba histolytica | nucleoside transporter, putative | 0.032 | 0.3843 | 1 |
Toxoplasma gondii | kinase, pfkB family protein | 0.0171 | 0.1873 | 0.5982 |
Brugia malayi | hypothetical protein | 0.0266 | 0.313 | 0.8146 |
Echinococcus multilocularis | equilibrative nucleoside transporter protein | 0.032 | 0.3843 | 0.3843 |
Trichomonas vaginalis | glyceraldehyde 3-phosphate dehydrogenase, putative | 0.0266 | 0.3131 | 0.7963 |
Echinococcus granulosus | g protein linked acetylcholine receptor gar 2a | 0.0266 | 0.313 | 0.7791 |
Echinococcus granulosus | rhodopsin orphan GPCR | 0.0266 | 0.313 | 0.7791 |
Toxoplasma gondii | glyceraldehyde-3-phosphate dehydrogenase GAPDH2 | 0.0266 | 0.3131 | 1 |
Loa Loa (eye worm) | G-protein coupled receptor | 0.0266 | 0.313 | 0.8146 |
Echinococcus granulosus | g protein coupled receptor | 0.0266 | 0.313 | 0.7791 |
Echinococcus granulosus | peptide allatostatin:somatostatin | 0.0266 | 0.313 | 0.7791 |
Trichomonas vaginalis | equilibrative nucleoside transporter, putative | 0.032 | 0.3843 | 1 |
Schistosoma mansoni | protein kinase | 0.0056 | 0.0351 | 0.1122 |
Toxoplasma gondii | nucleoside transporter protein | 0.0056 | 0.0351 | 0.1122 |
Brugia malayi | hypothetical protein | 0.0266 | 0.313 | 0.8146 |
Loa Loa (eye worm) | hypothetical protein | 0.0266 | 0.313 | 0.8146 |
Echinococcus multilocularis | orexin receptor type 2 | 0.0266 | 0.313 | 0.313 |
Activity type | Activity value | Assay description | Source | Reference |
---|---|---|---|---|
MST (functional) | ND 0 day | Antimalarial effect measured in trophozoite induced P. berghei mice at dose of 320 mg/kg after sc administration. | ChEMBL. | 7009867 |
MST (functional) | 0 day | Antimalarial effect measured against trophozoite induced Plasmodium berghei in mice at dosage of 80 mg/kg after sc administration; no data | ChEMBL. | 7009867 |
MST (functional) | 0 day | Antimalarial effect measured against trophozoite induced P. berghei in mice at dosage of 20 mg/kg after sc administration; no data | ChEMBL. | 7009867 |
MST (functional) | = 1.3 day | Antimalarial effect of the compound was measured against trophozoite induced Plasmodium berghei in mice at dosage of 20 mg/kg after subcutaneous administration. | ChEMBL. | 7009867 |
MST (functional) | = 1.3 day | Antimalarial effect of the compound was measured against trophozoite induced Plasmodium berghei in mice at dosage of 20 mg/kg after subcutaneous administration. | ChEMBL. | 7009867 |
MST (functional) | = 12.9 day | Antimalarial effect of the compound was measured against trophozoite induced P. berghei in mice at dosage of 640 mg/kg after sc administration; No. of mice surviving after 60 days 4 | ChEMBL. | 7009867 |
MST (functional) | = 12.9 day | Antimalarial activity against trophozoite induced P. berghei in mice at dosage of 160 mg/kg after sc administration | ChEMBL. | 7009867 |
MST (functional) | = 12.9 day | Antimalarial effect of the compound was measured against trophozoite induced Plasmodium berghei in mice after subcutaneous administration at 40 mg/kg | ChEMBL. | 7009867 |
MST (functional) | = 12.9 day | Antimalarial effect of the compound was measured against trophozoite induced P. berghei in mice at dosage of 640 mg/kg after sc administration; No. of mice surviving after 60 days 4 | ChEMBL. | 7009867 |
MST (functional) | = 12.9 day | Antimalarial activity against trophozoite induced P. berghei in mice at dosage of 160 mg/kg after sc administration | ChEMBL. | 7009867 |
MST (functional) | = 12.9 day | Antimalarial effect of the compound was measured against trophozoite induced Plasmodium berghei in mice after subcutaneous administration at 40 mg/kg | ChEMBL. | 7009867 |
MST (functional) | = 13.3 day | Antimalarial effect of the compound was measured against trophozoite induced Plasmodium berghei in mice after subcutaneous administration at 40 mg/kg | ChEMBL. | 7009867 |
MST (functional) | = 13.3 day | Antimalarial effect of the compound was measured against trophozoite induced Plasmodium berghei in mice after subcutaneous administration at 40 mg/kg | ChEMBL. | 7009867 |
MST (functional) | = 13.9 day | Antimalarial effect of the compound was measured against trophozoite induced P. berghei in mice at dosage of 160 mg/kg after sc administration; No. of mice surviving after 60 days 1 | ChEMBL. | 7009867 |
MST (functional) | = 13.9 day | Antimalarial effect of the compound was measured against trophozoite induced P. berghei in mice at dosage of 160 mg/kg after sc administration; No. of mice surviving after 60 days 1 | ChEMBL. | 7009867 |
MST (functional) | = 14.9 day | Antimalarial effect measured in trophozoite induced P. berghei mice at dose of 80 mg/kg after sc administration. | ChEMBL. | 7009867 |
MST (functional) | = 14.9 day | Antimalarial effect measured in trophozoite induced P. berghei mice at dose of 80 mg/kg after sc administration. | ChEMBL. | 7009867 |
MST (functional) | = 18.4 day | Antimalarial effect was measured against trophozoite induced Plasmodium berghei in mice at dosage of 640 mg/kg after subcutaneous administration. | ChEMBL. | 7009867 |
MST (functional) | = 18.4 day | Antimalarial effect was measured against trophozoite induced Plasmodium berghei in mice at dosage of 640 mg/kg after subcutaneous administration. | ChEMBL. | 7009867 |
MST (functional) | = 27.2 day | Antimalarial effect of the compound was measured against trophozoite induced P. berghei in mice at dosage of 320 mg/kg after sc administration; No. of mice surviving after 60 days 2 | ChEMBL. | 7009867 |
MST (functional) | = 27.2 day | Antimalarial effect of the compound was measured against trophozoite induced P. berghei in mice at dosage of 320 mg/kg after sc administration; No. of mice surviving after 60 days 2 | ChEMBL. | 7009867 |
No. of survivals (functional) | = 1 | Number of mice cured at a subcutaneous dose of 160 mg/kg. | ChEMBL. | 7009867 |
No. of survivals (functional) | = 2 | Number of mice cured at a subcutaneous dose of 320 mg/kg. | ChEMBL. | 7009867 |
No. of survivals (functional) | 3 | Number of mice cured at a dose of 640 mg/kg sc | ChEMBL. | 7009867 |
No. of survivals (functional) | = 4 | Number of mice cured at a dose of 640 mg/kg sc | ChEMBL. | 7009867 |
Ratio (functional) | ND 0 | The ratio of SD90 of the quinine hydrocloride, to the SD90 of the test substance for the Dose of mg/kg | ChEMBL. | 7009867 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.
1 literature reference was collected for this gene.