Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Onchocerca volvulus | 0.0498 | 0.3097 | 1 | |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L or K-like cysteine peptidase | 0.0498 | 0.3097 | 1 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.0498 | 0.3097 | 1 |
Trypanosoma cruzi | cysteine peptidase C (CPC), putative | 0.1006 | 1 | 1 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.0498 | 0.3097 | 1 |
Echinococcus multilocularis | cathepsin L cysteine protease | 0.0498 | 0.3097 | 0.3097 |
Loa Loa (eye worm) | cathepsin B | 0.039 | 0.1634 | 0.072 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0498 | 0.3097 | 1 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0498 | 0.3097 | 1 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0498 | 0.3097 | 1 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0498 | 0.3097 | 1 |
Echinococcus multilocularis | cathepsin L cysteine protease | 0.0498 | 0.3097 | 0.3097 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0498 | 0.3097 | 1 |
Leishmania major | cathepsin L-like protease | 0.0498 | 0.3097 | 1 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0498 | 0.3097 | 1 |
Brugia malayi | Cathepsin L-like cysteine proteinase | 0.0342 | 0.0985 | 0.0985 |
Echinococcus multilocularis | cysteine protease | 0.0498 | 0.3097 | 0.3097 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0498 | 0.3097 | 1 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0342 | 0.0985 | 0.3182 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0498 | 0.3097 | 1 |
Brugia malayi | Cathepsin L-like precursor | 0.0342 | 0.0985 | 0.0985 |
Entamoeba histolytica | cysteine protease, putative | 0.0498 | 0.3097 | 1 |
Giardia lamblia | Cathepsin B precursor | 0.039 | 0.1634 | 0.5 |
Onchocerca volvulus | Cathepsin L homolog | 0.0498 | 0.3097 | 1 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.0498 | 0.3097 | 1 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.0498 | 0.3097 | 1 |
Onchocerca volvulus | 0.0498 | 0.3097 | 1 | |
Onchocerca volvulus | 0.0498 | 0.3097 | 1 | |
Loa Loa (eye worm) | hypothetical protein | 0.0498 | 0.3097 | 0.2342 |
Schistosoma mansoni | cathepsin B-like peptidase (C01 family) | 0.039 | 0.1634 | 0.1634 |
Echinococcus granulosus | cathepsin l cysteine peptidase | 0.0498 | 0.3097 | 0.3097 |
Trypanosoma cruzi | cruzipain precursor, putative | 0.0498 | 0.3097 | 0.3097 |
Trypanosoma cruzi | cysteine peptidase, putative | 0.0498 | 0.3097 | 0.3097 |
Echinococcus multilocularis | cathepsin b | 0.1006 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.1006 | 1 | 1 |
Leishmania major | cathepsin L-like protease | 0.0498 | 0.3097 | 1 |
Trypanosoma cruzi | cysteine peptidase, putative | 0.0498 | 0.3097 | 0.3097 |
Entamoeba histolytica | cysteine proteinase, putative | 0.0498 | 0.3097 | 1 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0498 | 0.3097 | 1 |
Loa Loa (eye worm) | Papain cysteine protease/cathepsin propeptide inhibitor-containing protein | 0.0498 | 0.3097 | 0.2342 |
Plasmodium falciparum | cysteine proteinase falcipain 2b | 0.0498 | 0.3097 | 1 |
Echinococcus granulosus | cathepsin b | 0.1006 | 1 | 1 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0498 | 0.3097 | 1 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin B-like cysteine peptidase | 0.039 | 0.1634 | 0.5278 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0498 | 0.3097 | 1 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.0498 | 0.3097 | 1 |
Schistosoma mansoni | cathepsin B-like peptidase (C01 family) | 0.1006 | 1 | 1 |
Loa Loa (eye worm) | ctsf protein | 0.0498 | 0.3097 | 0.2342 |
Entamoeba histolytica | cysteine proteinase, putative | 0.0498 | 0.3097 | 1 |
Schistosoma mansoni | cathepsin B-like peptidase (C01 family) | 0.1006 | 1 | 1 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0498 | 0.3097 | 1 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0498 | 0.3097 | 1 |
Toxoplasma gondii | cathepsin CPL | 0.0498 | 0.3097 | 1 |
Leishmania major | cathepsin L-like protease | 0.0498 | 0.3097 | 1 |
Loa Loa (eye worm) | cysteine protease | 0.0498 | 0.3097 | 0.2342 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0498 | 0.3097 | 1 |
Leishmania major | cathepsin L-like protease | 0.0498 | 0.3097 | 1 |
Schistosoma mansoni | cathepsin F (C01 family) | 0.0498 | 0.3097 | 0.3097 |
Giardia lamblia | Cathepsin B precursor | 0.039 | 0.1634 | 0.5 |
Echinococcus multilocularis | cathepsin l cysteine peptidase | 0.0498 | 0.3097 | 0.3097 |
Brugia malayi | Cathepsin L-like precursor | 0.0498 | 0.3097 | 0.3097 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0498 | 0.3097 | 1 |
Plasmodium vivax | vivapain-2 | 0.0498 | 0.3097 | 1 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0498 | 0.3097 | 1 |
Brugia malayi | Papain family cysteine protease containing protein | 0.0498 | 0.3097 | 0.3097 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0498 | 0.3097 | 1 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.0498 | 0.3097 | 1 |
Trypanosoma brucei | cysteine peptidase C (CPC) | 0.039 | 0.1634 | 0.5278 |
Trypanosoma cruzi | cysteine peptidase, clan CA, family C1, cathepsin L-like, putative | 0.0342 | 0.0985 | 0.0985 |
Onchocerca volvulus | 0.0498 | 0.3097 | 1 | |
Brugia malayi | Cathepsin L-like precursor | 0.0498 | 0.3097 | 0.3097 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0498 | 0.3097 | 1 |
Echinococcus granulosus | cathepsin L cysteine proteinase | 0.0498 | 0.3097 | 0.3097 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0498 | 0.3097 | 1 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0498 | 0.3097 | 1 |
Entamoeba histolytica | cysteine proteinase, putative | 0.0342 | 0.0985 | 0.3182 |
Leishmania major | cysteine peptidase A (CPA) | 0.0498 | 0.3097 | 1 |
Brugia malayi | Cathepsin L-like precursor | 0.0498 | 0.3097 | 0.3097 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.0498 | 0.3097 | 1 |
Onchocerca volvulus | 0.0498 | 0.3097 | 1 | |
Giardia lamblia | Cathepsin B precursor | 0.039 | 0.1634 | 0.5 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0498 | 0.3097 | 1 |
Brugia malayi | cathepsin L-like precursor | 0.0342 | 0.0985 | 0.0985 |
Echinococcus granulosus | cathepsin l1 | 0.0498 | 0.3097 | 0.3097 |
Echinococcus granulosus | cathepsin l1 | 0.0342 | 0.0985 | 0.0985 |
Echinococcus multilocularis | cathepsin l cysteine peptidase | 0.0498 | 0.3097 | 0.3097 |
Brugia malayi | Cathepsin L-like precursor | 0.0342 | 0.0985 | 0.0985 |
Echinococcus multilocularis | cathepsin b | 0.1006 | 1 | 1 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0498 | 0.3097 | 1 |
Leishmania major | cathepsin L-like protease | 0.0498 | 0.3097 | 1 |
Loa Loa (eye worm) | papain family cysteine protease containing protein | 0.0498 | 0.3097 | 0.2342 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L or K-like cysteine peptidase | 0.0498 | 0.3097 | 1 |
Loa Loa (eye worm) | fibroinase | 0.0498 | 0.3097 | 0.2342 |
Onchocerca volvulus | 0.0498 | 0.3097 | 1 | |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0498 | 0.3097 | 1 |
Plasmodium falciparum | cysteine proteinase falcipain 2a | 0.0498 | 0.3097 | 1 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0498 | 0.3097 | 1 |
Brugia malayi | Cathepsin L-like precursor | 0.0498 | 0.3097 | 0.3097 |
Onchocerca volvulus | 0.0498 | 0.3097 | 1 | |
Leishmania major | cathepsin L-like protease | 0.0498 | 0.3097 | 1 |
Trypanosoma cruzi | cysteine peptidase, putative | 0.0498 | 0.3097 | 0.3097 |
Brugia malayi | Cathepsin L-like precursor | 0.0498 | 0.3097 | 0.3097 |
Brugia malayi | Cathepsin L-like precursor | 0.0498 | 0.3097 | 0.3097 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.0498 | 0.3097 | 1 |
Leishmania major | cathepsin L-like protease | 0.0498 | 0.3097 | 1 |
Onchocerca volvulus | Cathepsin L homolog | 0.0498 | 0.3097 | 1 |
Schistosoma mansoni | cathepsin F (C01 family) | 0.0342 | 0.0985 | 0.0985 |
Onchocerca volvulus | Cathepsin F homolog | 0.0498 | 0.3097 | 1 |
Schistosoma mansoni | SmCB2 peptidase (C01 family) | 0.1006 | 1 | 1 |
Schistosoma mansoni | cathepsin B-like peptidase (C01 family) | 0.1006 | 1 | 1 |
Plasmodium vivax | vivapain-2 | 0.0498 | 0.3097 | 1 |
Echinococcus multilocularis | cysteine protease | 0.0498 | 0.3097 | 0.3097 |
Trypanosoma cruzi | cysteine peptidase C (CPC), putative | 0.039 | 0.1634 | 0.1634 |
Echinococcus granulosus | cathepsin b | 0.1006 | 1 | 1 |
Schistosoma mansoni | cathepsin F (C01 family) | 0.0498 | 0.3097 | 0.3097 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.0498 | 0.3097 | 1 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0498 | 0.3097 | 1 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0342 | 0.0985 | 0.3182 |
Leishmania major | cathepsin L-like protease | 0.0498 | 0.3097 | 1 |
Trypanosoma cruzi | cysteine peptidase, putative | 0.0498 | 0.3097 | 0.3097 |
Plasmodium falciparum | cysteine proteinase falcipain 3 | 0.0498 | 0.3097 | 1 |
Species name | Source | Reference | Is orphan |
---|---|---|---|
Mus musculus | ChEMBL23 | 17149877 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.
1 literature reference was collected for this gene.