Detailed information for compound 410028

Basic information

Technical information
  • Name: Unnamed compound
  • MW: 334.413 | Formula: C24H18N2
  • H donors: 0 H acceptors: 0 LogP: 5.77 Rotable bonds: 4
    Rule of 5 violations (Lipinski): 1
  • SMILES: c1ccc2c(c1)c(/N=C/c1ccccc1)ccc2/N=C/c1ccccc1
  • InChi: 1S/C24H18N2/c1-3-9-19(10-4-1)17-25-23-15-16-24(22-14-8-7-13-21(22)23)26-18-20-11-5-2-6-12-20/h1-18H/b25-17+,26-18+
  • InChiKey: VWCZXIIPPIWFIV-RPCRKUJJSA-N  

Network

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Synonyms

No synonyms found for this compound

Targets

Known targets for this compound

No curated genes were found associated with this compound

Predicted pathogen targets for this compound

By orthology
No druggable targets predicted by orthology data
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity

Obtained from network model

Ranking Plot


Putative Targets List


Species Potential target Raw Global Species
Schistosoma mansoni tar DNA-binding protein 0.0062 0.0249 0.0571
Trypanosoma cruzi hypothetical protein, conserved 0.0035 0.0108 0.0151
Echinococcus multilocularis Alpha N acetylgalactosaminidase 0.0102 0.0451 0.1041
Trypanosoma cruzi cysteine peptidase, putative 0.1312 0.6651 1
Schistosoma mansoni hypothetical protein 0.0015 0.001 0.0015
Trypanosoma cruzi mitogen activated protein kinase 2, putative 0.0051 0.019 0.0274
Trypanosoma cruzi cysteine peptidase, clan CA, family C1, cathepsin L-like, putative 0.0128 0.0585 0.087
Echinococcus multilocularis mothers against decapentaplegic 5 0.0024 0.0056 0.0121
Trypanosoma cruzi P-type H+-ATPase, putative 0.0064 0.0257 0.0376
Giardia lamblia GTOR 0.0045 0.0159 0.2632
Trypanosoma brucei dihydrolipoamide dehydrogenase 0.0049 0.0182 0.2312
Entamoeba histolytica cysteine protease, putative 0.004 0.0137 0.1742
Brugia malayi Sodium/potassium-transporting ATPase alpha-3 chain, putative 0.0044 0.0155 0.0878
Trichomonas vaginalis Clan CA, family C1, cathepsin F-like cysteine peptidase 0.0018 0.0025 0.0156
Trypanosoma cruzi cysteine peptidase (N-terminal), putative 0.004 0.0137 0.0196
Echinococcus multilocularis dna polymerase eta 0.0162 0.0763 0.1768
Plasmodium falciparum dihydrolipoyl dehydrogenase, mitochondrial 0.0049 0.0182 0.2391
Trypanosoma brucei unspecified product 0.0131 0.0602 0.7869
Loa Loa (eye worm) hypothetical protein 0.0042 0.0145 0.0824
Brugia malayi follicle stimulating hormone receptor 0.0237 0.1143 0.6477
Schistosoma mansoni chromodomain helicase DNA binding protein 0.0035 0.0108 0.0242
Brugia malayi ATP-dependent DNA helicase, RecQ family protein 0.0019 0.0029 0.0162
Echinococcus granulosus expressed conserved protein 0.0092 0.04 0.0923
Schistosoma mansoni cpg binding protein 0.003 0.0085 0.0189
Trypanosoma brucei copper-transporting ATPase-like protein, putative 0.0032 0.0093 0.113
Brugia malayi hypothetical protein 0.002 0.0031 0.0176
Giardia lamblia Copper-transporting P-type ATPase 0.0032 0.0093 0.1331
Trypanosoma cruzi DNA polymerase kappa, putative 0.0138 0.0636 0.0946
Trichomonas vaginalis chromobox protein, putative 0.0035 0.0108 0.0887
Plasmodium falciparum ataxin-2 like protein, putative 0.0051 0.0194 0.2577
Echinococcus granulosus dihydrolipoamide dehydrogenase 0.0049 0.0182 0.0415
Echinococcus multilocularis neutral alpha glucosidase AB 0.0036 0.0114 0.0257
Leishmania major DNA polymerase eta, putative 0.0086 0.037 0.4801
Echinococcus multilocularis Basic leucine zipper (bZIP) transcription factor 0.0081 0.0347 0.08
Echinococcus granulosus plasma membrane calcium transporting ATPase 0.009 0.0394 0.0907
Entamoeba histolytica myb-like DNA-binding domain containing protein 0.0048 0.0175 0.2328
Trypanosoma brucei cytochrome P450, putative 0.0016 0.0011 0.0052
Plasmodium vivax vivapain-1 0.004 0.0137 0.1711
Echinococcus granulosus Ca2 transporting ATPase plasma membrane 0.009 0.0394 0.0907
Entamoeba histolytica cysteine proteinase, putative 0.004 0.0137 0.1742
Trypanosoma cruzi copper-transporting ATPase, putative 0.002 0.0033 0.0039
Brugia malayi hypothetical protein 0.0051 0.0194 0.1101
Schistosoma mansoni phosphatidylinositol 3-and 4-kinase 0.0015 0.0007 0.0008
Echinococcus granulosus Chromobox protein 3 0.0035 0.0108 0.0242
Brugia malayi hypothetical protein 0.0121 0.0553 0.3133
Loa Loa (eye worm) calcium ATPase 0.0022 0.0043 0.0241
Trypanosoma cruzi DNA damage repair protein, putative 0.0035 0.0108 0.0151
Schistosoma mansoni dipeptidyl-peptidase I (C01 family) 0.0018 0.0025 0.0049
Loa Loa (eye worm) hypothetical protein 0.0014 0.0004 0.0022
Schistosoma mansoni SmCB2 peptidase (C01 family) 0.0018 0.0025 0.0049
Trypanosoma cruzi hypothetical protein, conserved 0.0036 0.0114 0.0161
Schistosoma mansoni DNA polymerase IV / kappa 0.0035 0.0108 0.0242
Trypanosoma cruzi PAB1-binding protein , putative 0.0051 0.0194 0.0281
Mycobacterium ulcerans phosphopantetheinyl transferase, PptII 0.0023 0.005 0.0038
Trypanosoma brucei mitogen activated protein kinase 4, putative 0.0051 0.019 0.241
Schistosoma mansoni smad 0.0024 0.0056 0.0121
Mycobacterium ulcerans UDP-N-acetylglucosamine 1-carboxyvinyltransferase 0.1966 1 1
Loa Loa (eye worm) hypothetical protein 0.0036 0.0117 0.0665
Plasmodium vivax dihydrolipoyl dehydrogenase, mitochondrial, putative 0.0049 0.0182 0.2391
Plasmodium vivax P-type ATPase4, putative 0.0147 0.0682 1
Loa Loa (eye worm) hypothetical protein 0.0082 0.0353 0.2
Loa Loa (eye worm) papain family cysteine protease containing protein 0.0018 0.0025 0.0142
Mycobacterium tuberculosis Probable nitrite reductase [NAD(P)H] large subunit [FAD flavoprotein] NirB 0.0323 0.1585 0.2158
Trypanosoma cruzi plasma-membrane proton-efflux P-type ATPase, putative 0.0044 0.0155 0.0222
Leishmania major cathepsin L-like protease 0.015 0.0698 0.9132
Trypanosoma cruzi DNA damage repair protein, putative 0.0035 0.0108 0.0151
Plasmodium vivax holo-[acyl-carrier-protein] synthase, putative 0.0023 0.005 0.0374
Schistosoma mansoni polycystin 1-related 0.002 0.0031 0.0063
Leishmania major DNA damage repair protein, putative 0.0035 0.0108 0.1327
Trichomonas vaginalis cation-transporting ATPase, putative 0.0147 0.0682 0.5974
Mycobacterium leprae PROBABLE CATION-TRANSPORTER P-TYPE ATPASE B CTPB 0.0032 0.0093 0.0061
Giardia lamblia Plasma membrane calcium-transporting ATPase 2 0.008 0.0341 0.6214
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0056 0.022 0.1881
Loa Loa (eye worm) hypothetical protein 0.0035 0.0108 0.061
Schistosoma mansoni patched 1 0.0042 0.0145 0.0329
Toxoplasma gondii 4'-phosphopantetheinyl transferase superfamily protein 0.0023 0.005 0.0163
Loa Loa (eye worm) follicle stimulating hormone receptor 0.0237 0.1143 0.6477
Brugia malayi Corticotropin releasing factor receptor 2 precursor, putative 0.0049 0.0181 0.1028
Entamoeba histolytica glycosyl hydrolase, family 31 protein 0.0036 0.0114 0.1386
Schistosoma mansoni chromobox protein-related (chromobox 1) (heterochromatin 1) 0.0035 0.0108 0.0242
Loa Loa (eye worm) abnormal chemotaxis protein 14 0.0042 0.0145 0.0824
Loa Loa (eye worm) cysteine protease 0.0056 0.022 0.1246
Loa Loa (eye worm) hypothetical protein 0.0018 0.0025 0.0142
Brugia malayi cathepsin L-like cysteine proteinase 0.0018 0.0025 0.0142
Loa Loa (eye worm) hypothetical protein 0.0124 0.0565 0.3199
Loa Loa (eye worm) RecQ helicase 0.0046 0.0168 0.0949
Brugia malayi Valyl-tRNA synthetase 0.0035 0.0108 0.061
Entamoeba histolytica plasma membrane calcium ion-transporting ATPase, putative 0.0054 0.0207 0.282
Toxoplasma gondii LsmAD domain-containing protein 0.0051 0.0194 0.0686
Entamoeba histolytica cysteine protease, putative 0.004 0.0137 0.1742
Echinococcus granulosus chromobox protein 2 0.0035 0.0108 0.0242
Entamoeba histolytica cysteine protease, putative 0.004 0.0137 0.1742
Echinococcus granulosus chromodomain helicase DNA binding protein 1 0.0035 0.0108 0.0242
Echinococcus granulosus lipoxygenase domain containing protein 0.002 0.0031 0.0063
Echinococcus granulosus plasma membrane calcium transporting ATPase 2 0.011 0.0496 0.1146
Schistosoma mansoni hypothetical protein 0.0048 0.0176 0.04
Brugia malayi cahepsin L-like non-peptiedase homolog 0.0018 0.0025 0.0142
Mycobacterium ulcerans hypothetical protein 0.0035 0.0108 0.0097
Mycobacterium leprae PROBABLE CATION-TRANSPORTER ATPASE I CTPI 0.0068 0.0279 0.0323
Loa Loa (eye worm) Papain cysteine protease/cathepsin propeptide inhibitor-containing protein 0.0056 0.022 0.1246
Plasmodium falciparum DNA repair protein REV1, putative 0.0035 0.0108 0.1259
Echinococcus granulosus phosphatidylinositol 3 and 4 kinase 0.0015 0.0007 0.0008
Loa Loa (eye worm) TAR-binding protein 0.0062 0.0249 0.1413
Schistosoma mansoni chromobox protein 0.0035 0.0108 0.0242
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0049 0.0182 0.0263
Schistosoma mansoni cpg binding protein 0.003 0.0085 0.0189
Leishmania major hypothetical protein, conserved 0.0051 0.0194 0.2473
Onchocerca volvulus 0.01 0.0444 0.3882
Echinococcus multilocularis TGF beta signal transducer SmadC 0.0024 0.0056 0.0121
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0035 0.0108 0.0887
Entamoeba histolytica phospholipid-transporting P-type ATPase, putative 0.0032 0.0093 0.105
Chlamydia trachomatis dihydrolipoyl dehydrogenase 0.0049 0.0182 0.0133
Schistosoma mansoni cathepsin S (C01 family) 0.0018 0.0025 0.0049
Onchocerca volvulus 0.0034 0.0107 0.0914
Trichomonas vaginalis PIKK family atypical protein kinase 0.0033 0.0101 0.0825
Echinococcus granulosus Smad4 0.0024 0.0056 0.0121
Echinococcus multilocularis plasma membrane calcium transporting ATPase 0.009 0.0394 0.0907
Trichomonas vaginalis cation-transporting ATPase, putative 0.011 0.0496 0.4326
Schistosoma mansoni alpha glucosidase 0.0036 0.0114 0.0257
Trichomonas vaginalis conserved hypothetical protein 0.0056 0.0219 0.1874
Onchocerca volvulus 0.0062 0.025 0.2171
Echinococcus granulosus mitogen activated protein kinase 0.0051 0.019 0.0432
Schistosoma mansoni cathepsin C 0.0018 0.0025 0.0049
Leishmania major cathepsin L-like protease 0.0056 0.022 0.2811
Plasmodium vivax ataxin-2 like protein, putative 0.0051 0.0194 0.2577
Loa Loa (eye worm) hypothetical protein 0.0022 0.0043 0.0245
Echinococcus granulosus mitogen activated protein kinase 3 0.0051 0.019 0.0432
Onchocerca volvulus 0.0124 0.0564 0.4941
Schistosoma mansoni smad1 5 8 and 0.0024 0.0056 0.0121
Echinococcus multilocularis lysosomal alpha glucosidase 0.0161 0.0758 0.1756
Loa Loa (eye worm) animal heme peroxidase 0.0026 0.0062 0.0354
Entamoeba histolytica cysteine proteinase 1, putative 0.004 0.0137 0.1742
Trichomonas vaginalis Clan CA, family C1, cathepsin B-like cysteine peptidase 0.0018 0.0025 0.0156
Schistosoma mansoni cation-transporting atpase worm 0.0032 0.0093 0.0207
Brugia malayi Probable calcium-transporting ATPase KIAA0703 0.0095 0.0415 0.2352
Onchocerca volvulus 0.0049 0.0182 0.1571
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.0018 0.0025 0.0049
Brugia malayi hypothetical protein 0.0234 0.1131 0.6412
Echinococcus multilocularis phospholipid transporting ATPase IIB 0.0032 0.0093 0.0207
Mycobacterium ulcerans flavoprotein disulfide reductase 0.0049 0.0182 0.0171
Toxoplasma gondii calcium-translocating P-type ATPase, PMCA-type protein 0.011 0.0496 0.1777
Brugia malayi TAR-binding protein 0.0062 0.0249 0.1413
Brugia malayi hypothetical protein 0.0064 0.0258 0.1462
Mycobacterium leprae DIHYDROLIPOAMIDE DEHYDROGENASE LPD (LIPOAMIDE REDUCTASE (NADH)) (LIPOYL DEHYDROGENASE) (DIHYDROLIPOYL DEHYDROGENASE) (DIAPHORASE 0.0359 0.1769 0.2418
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0035 0.0108 0.0887
Loa Loa (eye worm) fibroinase 0.0056 0.022 0.1246
Trypanosoma brucei calcium motive p-type ATPase, putative 0.008 0.0341 0.4419
Onchocerca volvulus 0.0056 0.022 0.1906
Echinococcus multilocularis Na+:K+ ATPase alpha subunit 0.008 0.0341 0.0786
Toxoplasma gondii CMGC kinase, MAPK family (ERK) MAPK-1 0.0051 0.019 0.0669
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.015 0.0698 0.9132
Echinococcus granulosus Polycystic kidney disease protein 0.002 0.0031 0.0063
Trichomonas vaginalis chromobox protein, putative 0.0097 0.0427 0.3713
Echinococcus granulosus RUN 0.002 0.0031 0.0063
Schistosoma mansoni hypothetical protein 0.0033 0.0102 0.0229
Trichomonas vaginalis conserved hypothetical protein 0.0035 0.0108 0.0887
Trichomonas vaginalis PIKK family atypical protein kinase 0.003 0.0084 0.0678
Loa Loa (eye worm) E1-E2 ATPase 0.0064 0.0257 0.1458
Leishmania major vacuolar-type Ca2 -ATPase, putative 0.011 0.0496 0.6464
Trichomonas vaginalis r2r3-MYB transcription factor, putative 0.0048 0.0175 0.1486
Mycobacterium ulcerans metal cation-transporting p-type ATPase F, CtpF 0.0147 0.0682 0.0671
Loa Loa (eye worm) RNA recognition domain-containing protein domain-containing protein 0.0062 0.0249 0.1413
Onchocerca volvulus Peroxidase homolog 0.0026 0.0062 0.0517
Schistosoma mansoni tar DNA-binding protein 0.0062 0.0249 0.0571
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0056 0.022 0.1881
Loa Loa (eye worm) glycosyl hydrolase family 31 protein 0.0161 0.0758 0.4296
Echinococcus multilocularis arachidonate 5 lipoxygenase 0.0055 0.0211 0.0483
Brugia malayi MH2 domain containing protein 0.0358 0.1765 1
Echinococcus granulosus dna polymerase eta 0.0162 0.0763 0.1768
Loa Loa (eye worm) cytoplasmic intermediate filament protein 0.0014 0.0004 0.0024
Loa Loa (eye worm) animal heme peroxidase 0.0026 0.0062 0.0354
Trichomonas vaginalis pc-MYB2, putative 0.0048 0.0175 0.1486
Trypanosoma cruzi DNA polymerase kappa, putative 0.0138 0.0636 0.0946
Schistosoma mansoni lamin 0.0027 0.0068 0.0149
Loa Loa (eye worm) cytochrome P450 family protein 0.0026 0.0064 0.0361
Echinococcus granulosus microtubule associated protein 2 0.0684 0.3434 0.7986
Trichomonas vaginalis DNA polymerase eta, putative 0.0138 0.0636 0.5564
Echinococcus granulosus dna polymerase kappa 0.0138 0.0636 0.1471
Brugia malayi Cathepsin L-like precursor 0.0056 0.022 0.1246
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0056 0.022 0.1881
Trichomonas vaginalis r2r3-MYB transcription factor, putative 0.0048 0.0176 0.1497
Trichomonas vaginalis PIKK family atypical protein kinase 0.0033 0.0101 0.0825
Trichomonas vaginalis PIKK family atypical protein kinase 0.0045 0.0159 0.1343
Echinococcus granulosus lamin 0.0027 0.0068 0.0149
Onchocerca volvulus Peroxidasin homolog 0.0026 0.0062 0.0517
Echinococcus multilocularis protein dispatched 1 0.0048 0.0176 0.04
Trypanosoma cruzi cation-transporting ATPase, putative 0.0032 0.0093 0.0128
Loa Loa (eye worm) cytochrome P450 family protein 0.0016 0.0011 0.0064
Brugia malayi Doublecortin family protein 0.002 0.0031 0.0176
Trichomonas vaginalis plasma membrane calcium-transporting ATPase, putative 0.011 0.0496 0.4326
Brugia malayi hypothetical protein 0.002 0.0031 0.0176
Onchocerca volvulus Heterochromatin protein 1 homolog 0.0097 0.0427 0.3731
Loa Loa (eye worm) hypothetical protein 0.01 0.0444 0.2515
Onchocerca volvulus 0.0026 0.0062 0.0517
Schistosoma mansoni alpha-glucosidase 0.0139 0.0643 0.1487
Schistosoma mansoni dihydrolipoamide dehydrogenase 0.0049 0.0182 0.0415
Schistosoma mansoni na+/k+ atpase alpha subunit 0.008 0.0341 0.0786
Trichomonas vaginalis conserved hypothetical protein 0.0035 0.0108 0.0887
Echinococcus multilocularis musashi 0.0027 0.0068 0.0149
Trichomonas vaginalis conserved hypothetical protein 0.0018 0.0025 0.0156
Trichomonas vaginalis cation-transporting ATPase, putative 0.0147 0.0682 0.5974
Trypanosoma brucei DNA polymerase kappa, putative 0.0138 0.0636 0.8313
Mycobacterium tuberculosis Probable NADH dehydrogenase Ndh 0.0323 0.1585 0.2158
Echinococcus multilocularis terminal deoxycytidyl transferase rev1 0.0111 0.0501 0.1156
Trypanosoma cruzi cytochrome P450, putative 0.0016 0.0011 0.0006
Onchocerca volvulus 0.0028 0.0077 0.0642
Echinococcus multilocularis bloom syndrome protein 0.0046 0.0168 0.0381
Brugia malayi Protein cec-1. 0.0035 0.0108 0.061
Trypanosoma brucei DNA polymerase kappa, putative 0.0138 0.0636 0.8313
Trypanosoma brucei DNA polymerase kappa, putative 0.0138 0.0636 0.8313
Loa Loa (eye worm) hypothetical protein 0.0079 0.0336 0.1904
Entamoeba histolytica calcium-transporting P-type ATPase, putative 0.01 0.0444 0.649
Trypanosoma cruzi cysteine peptidase, putative 0.0056 0.022 0.032
Trypanosoma brucei cation-transporting ATPase, putative 0.0032 0.0093 0.113
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0018 0.0025 0.0156
Schistosoma mansoni ATPase 0.0147 0.0682 0.1579
Leishmania major 2-oxoglutarate dehydrogenase, e3 component, lipoamidedehydrogenase-like protein 0.0049 0.0182 0.2312
Schistosoma mansoni cathepsin B (C01 family) 0.0018 0.0025 0.0049
Entamoeba histolytica myb-like DNA-binding domain containing protein 0.0048 0.0175 0.2328
Brugia malayi Thioredoxin reductase 0.0142 0.0656 0.3717
Echinococcus multilocularis lipoxygenase domain containing protein 0.002 0.0031 0.0063
Echinococcus multilocularis Ankyrin repeat domain containing protein 0.0089 0.0387 0.0892
Onchocerca volvulus 0.0064 0.0258 0.2242
Trypanosoma brucei DNA polymerase kappa, putative 0.0061 0.0243 0.3114
Leishmania major calcium motive p-type ATPase, putative 0.008 0.0341 0.4419
Trypanosoma cruzi cruzipain precursor, putative 0.015 0.0698 0.1039
Trichomonas vaginalis maltase-glucoamylase, putative 0.0036 0.0114 0.0948
Entamoeba histolytica hypothetical protein 0.0023 0.005 0.0381
Treponema pallidum NADH oxidase 0.0049 0.0182 0.0149
Brugia malayi Glycosyl hydrolases family 31 protein 0.0036 0.0114 0.0649
Plasmodium vivax vivapain-2 0.0056 0.022 0.2966
Plasmodium vivax thioredoxin reductase, putative 0.0142 0.0656 0.9602
Treponema pallidum 4'-phosphopantetheinyl transferase 0.0023 0.005 0.0016
Schistosoma mansoni hypothetical protein 0.0015 0.001 0.0015
Echinococcus granulosus nuclear factor of activated T cells 5 0.0073 0.0305 0.07
Echinococcus granulosus ATP dependent DNA helicase Q5 0.0019 0.0029 0.0057
Loa Loa (eye worm) hypothetical protein 0.0019 0.0029 0.0162
Echinococcus multilocularis microtubule associated protein 2 0.0684 0.3434 0.7986
Trypanosoma brucei dihydrolipoyl dehydrogenase 0.0049 0.0182 0.2312
Echinococcus multilocularis lamin 0.0027 0.0068 0.0149
Mycobacterium ulcerans dihydrolipoamide dehydrogenase, LpdB 0.0049 0.0182 0.0171
Trypanosoma cruzi P-type H+-ATPase, putative 0.0044 0.0155 0.0222
Trypanosoma cruzi calcium-translocating P-type ATPase, putative 0.0044 0.0155 0.0222
Brugia malayi hypothetical protein 0.0026 0.0062 0.0354
Mycobacterium ulcerans cation transporter p-type ATPase a CtpA 0.0032 0.0093 0.0082
Echinococcus granulosus neuropeptide s receptor 0.0465 0.2311 0.537
Trichomonas vaginalis r2r3-MYB transcription factor, putative 0.0048 0.0175 0.1486
Schistosoma mansoni calcium-transporting atpase sarcoplasmic/endoplasmic reticulum type (calcium pump) 0.0127 0.058 0.134
Entamoeba histolytica cysteine proteinase, putative 0.004 0.0137 0.1742
Trichomonas vaginalis conserved hypothetical protein 0.0035 0.0108 0.0887
Trichomonas vaginalis PIKK family atypical protein kinase 0.0045 0.0159 0.1343
Entamoeba histolytica myb-like DNA-binding domain containing protein 0.0048 0.0175 0.2328
Brugia malayi Glycosyl hydrolases family 31 protein 0.0161 0.0758 0.4296
Echinococcus granulosus ankyrin repeat and death domain containing protein 0.0014 0.0004 0.000000044333
Plasmodium falciparum ADP-dependent DNA helicase RecQ 0.0041 0.0139 0.1732
Echinococcus multilocularis cysteine protease 0.0056 0.022 0.0503
Schistosoma mansoni Na+/K+ transporting ATPase subunit alpha 0.01 0.0444 0.1024
Trypanosoma cruzi DNA polymerase kappa, putative 0.0138 0.0636 0.0946
Toxoplasma gondii Myb family DNA-binding domain-containing protein 0.0048 0.0176 0.0622
Echinococcus multilocularis copper transporting ATPase 1 0.0032 0.0093 0.0207
Trichomonas vaginalis alpha-glucosidase, putative 0.0036 0.0114 0.0948
Echinococcus multilocularis cysteine protease 0.0056 0.022 0.0503
Giardia lamblia Potassium-transporting ATPase alpha chain 1 0.008 0.0341 0.6214
Echinococcus multilocularis X box binding protein 1 0.0286 0.1394 0.3235
Schistosoma mansoni hypothetical protein 0.004 0.0138 0.0311
Plasmodium vivax ADP-dependent DNA helicase RecQ, putative 0.0031 0.0091 0.1003
Schistosoma mansoni cathepsin F (C01 family) 0.0056 0.022 0.0503
Brugia malayi glutathione reductase 0.0142 0.0656 0.3717
Entamoeba histolytica hypothetical protein 0.0035 0.0108 0.128
Leishmania major calcium-transporting ATPase, putative 0.008 0.0341 0.4419
Trypanosoma brucei DNA polymerase kappa, putative 0.0083 0.0357 0.463
Toxoplasma gondii ATP-dependent DNA helicase, RecQ family protein 0.0019 0.0029 0.0087
Mycobacterium tuberculosis Conserved hypothetical protein 0.0111 0.0501 0.0634
Echinococcus granulosus cation transporting atpase worm 0.0032 0.0093 0.0207
Loa Loa (eye worm) hypothetical protein 0.0234 0.1131 0.6412
Mycobacterium tuberculosis Putative ferredoxin reductase 0.0323 0.1585 0.2158
Trichomonas vaginalis MYB72, putative 0.0048 0.0175 0.1486
Entamoeba histolytica cysteine protease, putative 0.0056 0.022 0.3019
Echinococcus multilocularis chromobox protein 1 0.0153 0.0715 0.1655
Trypanosoma cruzi P-type H+-ATPase, putative 0.0064 0.0257 0.0376
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.0018 0.0025 0.0049
Loa Loa (eye worm) hypothetical protein 0.0026 0.0062 0.0354
Giardia lamblia DINP protein human, muc B family 0.0118 0.0534 1
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0037 0.0123 0.1023
Trichomonas vaginalis conserved hypothetical protein 0.0035 0.0108 0.0887
Plasmodium falciparum chromodomain-helicase-DNA-binding protein 1 homolog, putative 0.0035 0.0108 0.1257
Trypanosoma brucei DNA polymerase kappa, putative 0.0083 0.0357 0.463
Trichomonas vaginalis ATPase, class VI, type 11C, putative 0.0032 0.0093 0.0756
Toxoplasma gondii cathepsin CPL 0.0056 0.022 0.0779
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0018 0.0025 0.0156
Loa Loa (eye worm) hypothetical protein 0.0018 0.0025 0.0142
Mycobacterium tuberculosis Probable UDP-N-acetylglucosamine 1-carboxyvinyltransferase MurA 0.1412 0.7161 1
Loa Loa (eye worm) hypothetical protein 0.0147 0.0682 0.3865
Echinococcus multilocularis cathepsin L cysteine protease 0.0056 0.022 0.0503
Brugia malayi cytoplasmic intermediate filament protein 0.0014 0.0004 0.0024
Loa Loa (eye worm) hypothetical protein 0.0026 0.0062 0.0354
Schistosoma mansoni hypothetical protein 0.0144 0.067 0.1551
Leishmania major mitogen activated protein kinase, putative,map kinase, putative 0.0051 0.019 0.241
Giardia lamblia Plasma membrane calcium-transporting ATPase 2 0.011 0.0496 0.925
Trypanosoma brucei DNA damage repair protein, putative 0.0035 0.0108 0.1327
Brugia malayi MH2 domain containing protein 0.0024 0.0056 0.0316
Entamoeba histolytica cysteine protease, putative 0.004 0.0137 0.1742
Toxoplasma gondii cation-transporting atpase family protein 0.002 0.0033 0.0104
Trichomonas vaginalis cation-transporting ATPase, putative 0.0032 0.0093 0.0756
Entamoeba histolytica cysteine protease, putative 0.004 0.0137 0.1742
Onchocerca volvulus 0.0082 0.0353 0.308
Loa Loa (eye worm) phosphatidylinositol 3 0.0045 0.0159 0.0901
Trypanosoma cruzi Calcium ATPase SERCA-like 0.0147 0.0682 0.1015
Entamoeba histolytica recQ family helicase, putative 0.0025 0.0057 0.0501
Schistosoma mansoni hypothetical protein 0.004 0.0138 0.0311
Brugia malayi dihydrolipoyl dehydrogenase, mitochondrial precursor, putative 0.0049 0.0182 0.1032
Brugia malayi Melibiase family protein 0.0068 0.0278 0.1574
Brugia malayi Heterochromatin protein 1 0.0153 0.0715 0.4051
Mycobacterium tuberculosis Probable oxidoreductase 0.0359 0.1769 0.2418
Trichomonas vaginalis CMGC family protein kinase 0.0051 0.019 0.1613
Trypanosoma cruzi cysteine proteinase, putative 0.004 0.0137 0.0196
Entamoeba histolytica myb-like DNA-binding domain containing protein 0.0048 0.0175 0.2328
Echinococcus multilocularis chromobox protein 2 0.0035 0.0108 0.0242
Schistosoma mansoni lipoxygenase 0.0055 0.0211 0.0483
Schistosoma mansoni cation-transporting atpase 13a1 (G-box binding protein) 0.0032 0.0093 0.0207
Plasmodium falciparum cysteine proteinase falcipain 2b 0.0056 0.022 0.2966
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.015 0.0698 0.9132
Entamoeba histolytica cysteine protease, putative 0.004 0.0137 0.1742
Plasmodium falciparum conserved Plasmodium protein, unknown function 0.0035 0.0108 0.1257
Brugia malayi Death domain containing protein 0.0014 0.0004 0.0022
Trichomonas vaginalis conserved hypothetical protein 0.0091 0.0396 0.3439
Mycobacterium ulcerans cation transporter p-type ATPase D CtpD 0.0032 0.0093 0.0082
Onchocerca volvulus 0.0026 0.0062 0.0517
Loa Loa (eye worm) immunoglobulin I-set domain-containing protein 0.0014 0.0004 0.0022
Loa Loa (eye worm) hypothetical protein 0.0015 0.001 0.0058
Entamoeba histolytica cysteine protease, putative 0.004 0.0137 0.1742
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.003 0.0086 0.019
Loa Loa (eye worm) helicase 0.0035 0.0108 0.061
Schistosoma mansoni histone-lysine n-methyltransferase suv9 0.0065 0.0262 0.0602
Chlamydia trachomatis metal transport ATPase 0.0032 0.0093 0.0043
Leishmania major P-type H -ATPase, putative 0.0064 0.0257 0.3306
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0056 0.022 0.1881
Onchocerca volvulus 0.0018 0.0025 0.0186
Trichomonas vaginalis conserved hypothetical protein 0.0035 0.0108 0.0887
Plasmodium falciparum heterochromatin protein 1 0.0035 0.0108 0.1257
Loa Loa (eye worm) intermediate filament tail domain-containing protein 0.0027 0.0068 0.0384
Echinococcus multilocularis ATP dependent DNA helicase Q1 0.0019 0.0029 0.0057
Trichomonas vaginalis PIKK family atypical protein kinase 0.0027 0.0067 0.053
Trypanosoma brucei PAB1-binding protein , putative 0.0051 0.0194 0.2473
Trypanosoma cruzi PAB1-binding protein , putative 0.0051 0.0194 0.0281
Brugia malayi Animal haem peroxidase family protein 0.0026 0.0062 0.0354
Onchocerca volvulus Chorion peroxidase homolog 0.0026 0.0062 0.0517
Trichomonas vaginalis PIKK family atypical protein kinase 0.0026 0.0066 0.0518
Echinococcus granulosus FKBP12 rapamycin complex associated protein 0.0045 0.0159 0.0361
Plasmodium vivax calcium-transporting ATPase, putative 0.0147 0.0682 1
Loa Loa (eye worm) MH1 domain-containing protein 0.0024 0.0056 0.0316
Trichomonas vaginalis PIKK family atypical protein kinase 0.0024 0.0054 0.0413
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0056 0.022 0.1881
Trypanosoma brucei DNA polymerase kappa, putative 0.0138 0.0636 0.8313
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0056 0.022 0.1881
Entamoeba histolytica phospholipid-transporting P-type ATPase, putative 0.0032 0.0093 0.105
Brugia malayi hypothetical protein 0.0033 0.0101 0.0572
Trichomonas vaginalis conserved hypothetical protein 0.0035 0.0108 0.0887
Entamoeba histolytica cysteine proteinase, putative 0.0034 0.0107 0.1277
Schistosoma mansoni phosphoserine phosphatase 0.002 0.0033 0.0069
Trypanosoma brucei DNA polymerase kappa, putative 0.0138 0.0636 0.8313
Loa Loa (eye worm) hypothetical protein 0.0026 0.0062 0.0354
Trichomonas vaginalis plasma membrane calcium-transporting ATPase, putative 0.011 0.0496 0.4326
Mycobacterium ulcerans metal cation transporter p-type ATPase a 0.01 0.0444 0.0433
Brugia malayi RNA binding protein 0.0062 0.0249 0.1413
Echinococcus granulosus mothers against decapentaplegic 5 0.0024 0.0056 0.0121
Trichomonas vaginalis DNA helicase recq, putative 0.0025 0.0057 0.0442
Trichomonas vaginalis Clan CA, family C1, cathepsin B-like cysteine peptidase 0.0018 0.0025 0.0156
Schistosoma mansoni calcium-transporting atpase 2 (atpase 2) 0.0127 0.058 0.134
Echinococcus multilocularis tar DNA binding protein 0.0062 0.0249 0.0571
Trypanosoma cruzi DNA polymerase kappa, putative 0.0138 0.0636 0.0946
Trichomonas vaginalis Clan CA, family C1, cathepsin B-like cysteine peptidase 0.0018 0.0025 0.0156
Loa Loa (eye worm) CHromoDomain protein family member 0.0036 0.0116 0.0657
Loa Loa (eye worm) CMGC/MAPK/ERK1 protein kinase 0.0051 0.019 0.1074
Entamoeba histolytica Plasma membrane calcium-transporting ATPase, putative 0.011 0.0496 0.7298
Loa Loa (eye worm) hypothetical protein 0.0034 0.0107 0.0609
Schistosoma mansoni ataxia telangiectasia mutated (atm)-related 0.0045 0.0159 0.0361
Echinococcus multilocularis cathepsin b 0.0018 0.0025 0.0049
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.015 0.0698 0.9132
Echinococcus multilocularis neuropeptide s receptor 0.0465 0.2311 0.537
Echinococcus granulosus L aminoadipate semialdehyde 0.0082 0.0353 0.0813
Trypanosoma brucei ATP-dependent DEAD/H DNA helicase recQ, putative 0.0025 0.0057 0.066
Schistosoma mansoni multiple ankyrin repeats single kh domain protein 0.0089 0.0387 0.0892
Loa Loa (eye worm) doublecortin family protein 0.002 0.0031 0.0176
Entamoeba histolytica cation-transporting P-typeATPase, putative 0.0032 0.0093 0.105
Plasmodium falciparum cysteine proteinase falcipain 3 0.0056 0.022 0.2966
Brugia malayi Animal haem peroxidase family protein 0.0026 0.0062 0.0354
Schistosoma mansoni hypothetical protein 0.0015 0.001 0.0015
Trypanosoma cruzi calcium motive p-type ATPase, putative 0.008 0.0341 0.0503
Onchocerca volvulus Peroxidase homolog 0.0026 0.0062 0.0517
Leishmania major phosphopantetheinyl transferase-like protein 0.0023 0.005 0.0558
Echinococcus multilocularis cpg binding protein 0.003 0.0085 0.0189
Schistosoma mansoni lamin 0.0027 0.0068 0.0149
Brugia malayi E1-E2 ATPase family protein 0.0032 0.0093 0.0526
Brugia malayi Type III restriction enzyme, res subunit family protein 0.0035 0.0108 0.061
Echinococcus multilocularis cathepsin l cysteine peptidase 0.0056 0.022 0.0503
Trichomonas vaginalis alpha-glucosidase, putative 0.0036 0.0114 0.0948
Echinococcus multilocularis mitogen activated protein kinase 3 0.0051 0.019 0.0432
Mycobacterium tuberculosis Cation transporter P-type ATPase a CtpA 0.0032 0.0093 0.0061
Toxoplasma gondii NADPH-glutathione reductase 0.0049 0.0182 0.0642
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0034 0.0107 0.0886
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0056 0.022 0.1881
Schistosoma mansoni aminoadipate-semialdehyde dehydrogenase 0.0082 0.0353 0.0813
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.0018 0.0025 0.0049
Brugia malayi MH1 domain containing protein 0.0024 0.0056 0.0316
Mycobacterium tuberculosis Probable dehydrogenase 0.0323 0.1585 0.2158
Trichomonas vaginalis Clan CA, family C1, cathepsin L or K-like cysteine peptidase 0.0056 0.022 0.1881
Trypanosoma cruzi calcium motive p-type ATPase, putative 0.008 0.0341 0.0503
Echinococcus granulosus Na:K ATPase alpha subunit 0.008 0.0341 0.0786
Brugia malayi hypothetical protein 0.002 0.0033 0.0189
Schistosoma mansoni alpha-glucosidase 0.0139 0.0643 0.1487
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.004 0.0137 0.1151
Entamoeba histolytica cysteine proteinase, putative 0.004 0.0137 0.1742
Trichomonas vaginalis C-MYB, putative 0.0048 0.0175 0.1486
Echinococcus multilocularis lysosomal alpha glucosidase 0.0161 0.0758 0.1756
Brugia malayi cathepsin L precursor 0.0018 0.0025 0.0142
Brugia malayi Immunoglobulin I-set domain containing protein 0.0014 0.0004 0.0022
Plasmodium vivax multidomain scavenger receptor, putative 0.002 0.0031 0.0091
Leishmania major cathepsin L-like protease 0.0056 0.022 0.2811
Leishmania major dihydrolipoamide dehydrogenase, putative 0.0049 0.0182 0.2312
Echinococcus multilocularis Ankyrin 0.0014 0.0005 0.0001
Brugia malayi cathepsin F-like cysteine proteinase 0.0022 0.0043 0.0245
Trichomonas vaginalis PIKK family atypical protein kinase 0.0035 0.0112 0.0929
Entamoeba histolytica glycosyl hydrolase, family 31 protein 0.0036 0.0114 0.1386
Echinococcus granulosus cathepsin b 0.0018 0.0025 0.0049
Echinococcus multilocularis phosphoserine phosphatase 0.002 0.0033 0.0069
Brugia malayi Sodium/potassium-transporting ATPase alpha chain, putative 0.0068 0.0279 0.1583
Plasmodium falciparum LCCL domain-containing protein 0.002 0.0031 0.0091
Schistosoma mansoni transcription factor LCR-F1 0.0144 0.067 0.1551
Echinococcus granulosus sterol regulatory element binding protein 0.0042 0.0145 0.0329
Schistosoma mansoni smad1 5 8 and 0.0024 0.0056 0.0121
Echinococcus multilocularis sarco:endoplasmic reticulum calcium ATPase 0.0147 0.0682 0.1579
Echinococcus granulosus geminin 0.0853 0.43 1
Brugia malayi Papain family cysteine protease containing protein 0.0018 0.0025 0.0142
Loa Loa (eye worm) cytochrome P450 family protein 0.0016 0.0011 0.0064
Brugia malayi M-phase phosphoprotein, mpp8 0.0124 0.0564 0.3196
Trypanosoma brucei hypothetical protein, conserved 0.0035 0.0108 0.1327
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0041 0.0141 0.118
Schistosoma mansoni hypothetical protein 0.0853 0.43 1
Leishmania major calcium-translocating P-type ATPase 0.0147 0.0682 0.8926
Trypanosoma cruzi mitogen-activated protein kinase 11, putative 0.0051 0.019 0.0274
Loa Loa (eye worm) hypothetical protein 0.0026 0.0062 0.0354
Brugia malayi aminoadipate-semialdehyde dehydrogenase-phosphopantetheinyl transferase 0.0082 0.0353 0.2
Echinococcus multilocularis nuclear factor of activated T cells 5 0.0073 0.0305 0.07
Schistosoma mansoni DNA helicase recq5 0.0019 0.0029 0.0057
Trichomonas vaginalis conserved hypothetical protein 0.0091 0.0396 0.3439
Trypanosoma brucei dihydrolipoamide dehydrogenase 0.0049 0.0182 0.2312
Echinococcus multilocularis protein patched 0.0042 0.0145 0.0329
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0049 0.0182 0.0263
Mycobacterium ulcerans dihydrolipoamide dehydrogenase 0.0049 0.0182 0.0171
Loa Loa (eye worm) hypothetical protein 0.0026 0.0062 0.0354
Trypanosoma cruzi plasma membrane Ca2+ ATPase 0.011 0.0496 0.0735
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0041 0.0141 0.118
Schistosoma mansoni hypothetical protein 0.004 0.0138 0.0311
Trichomonas vaginalis MYB3r3, putative 0.0048 0.0175 0.1486
Loa Loa (eye worm) glycosyl hydrolase family 31 protein 0.0036 0.0114 0.0649
Trypanosoma cruzi cysteine peptidase, putative 0.015 0.0698 0.1039
Toxoplasma gondii cathepsin B 0.0018 0.0025 0.0074
Loa Loa (eye worm) Na,K-ATPase alpha subunit 0.01 0.0444 0.2515
Toxoplasma gondii phospholipid-translocating P-type ATPase, flippase subfamily protein 0.002 0.0033 0.0104
Trypanosoma cruzi Phosphatidylinositol 3-kinase tor2 0.0045 0.0159 0.0228
Loa Loa (eye worm) hypothetical protein 0.0026 0.0062 0.0354
Trypanosoma cruzi cysteine peptidase, putative 0.015 0.0698 0.1039
Loa Loa (eye worm) MH2 domain-containing protein 0.0358 0.1765 1
Schistosoma mansoni subfamily C1A unassigned peptidase (C01 family) 0.0018 0.0025 0.0049
Echinococcus multilocularis chromodomain helicase DNA binding protein 1 0.0035 0.0108 0.0242
Mycobacterium ulcerans cation-transporter p-type ATPase B CtpB 0.0032 0.0093 0.0082
Leishmania major DNA polymerase eta, putative 0.0162 0.0763 1
Toxoplasma gondii P-type ATPase4, putative 0.01 0.0444 0.1589
Entamoeba histolytica phosphatidylinositol3-kinaseTor2, putative 0.0045 0.0159 0.2077
Leishmania major acetoin dehydrogenase e3 component-like protein 0.0049 0.0182 0.2312
Mycobacterium tuberculosis Dihydrolipoamide dehydrogenase LpdC (lipoamide reductase (NADH)) (lipoyl dehydrogenase) (dihydrolipoyl dehydrogenase) (diaphoras 0.0359 0.1769 0.2418
Trichomonas vaginalis conserved hypothetical protein 0.0056 0.0219 0.1874
Trypanosoma cruzi ATP-dependent DEAD/H DNA helicase recQ, putative 0.0025 0.0057 0.0075
Schistosoma mansoni terminal deoxycytidyl transferase 0.0111 0.0501 0.1156
Trichomonas vaginalis PIKK family atypical protein kinase 0.0029 0.0079 0.0634
Loa Loa (eye worm) intermediate filament protein 0.0027 0.0068 0.0384
Trypanosoma cruzi cysteine peptidase, putative 0.004 0.0137 0.0196
Trichomonas vaginalis PIKK family atypical protein kinase 0.0035 0.0112 0.0929
Trichomonas vaginalis DNA helicase recq1, putative 0.0046 0.0168 0.1418
Echinococcus granulosus neutral alpha glucosidase AB 0.0036 0.0114 0.0257
Echinococcus granulosus cpg binding protein 0.003 0.0085 0.0189
Trichomonas vaginalis sucrase-isomaltase, putative 0.0036 0.0114 0.0948
Mycobacterium tuberculosis Probable metal cation transporter P-type ATPase A CtpF 0.0046 0.0169 0.0168
Echinococcus granulosus sarco:endoplasmic reticulum calcium ATPase 0.0147 0.0682 0.1579
Trypanosoma brucei hypothetical protein, conserved 0.0035 0.0108 0.1327
Echinococcus granulosus calcium transporting atpase 0.0127 0.058 0.134
Echinococcus multilocularis lipoxygenase domain containing protein 0.002 0.0031 0.0063
Trichomonas vaginalis Clan CA, family C1, cathepsin L, S or H-like cysteine peptidase 0.0018 0.0025 0.0156
Echinococcus multilocularis geminin 0.0853 0.43 1
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0056 0.022 0.1881
Mycobacterium tuberculosis Probable cation transporter P-type ATPase D CtpD 0.0032 0.0093 0.0061
Trypanosoma cruzi dihydrolipoyl dehydrogenase, putative 0.0049 0.0182 0.0263
Schistosoma mansoni SmCL2-like peptidase (C01 family) 0.004 0.0137 0.0311
Loa Loa (eye worm) hypothetical protein 0.0054 0.0207 0.1173
Echinococcus granulosus cathepsin L cysteine proteinase 0.0056 0.022 0.0503
Schistosoma mansoni plasma membrane calcium-transporting atpase 0.009 0.0394 0.0907
Mycobacterium ulcerans metal cation-transporting p-type ATPase CtpC 0.0032 0.0093 0.0082
Trichomonas vaginalis Clan CA, family C1, cathepsin B-like cysteine peptidase 0.0018 0.0025 0.0156
Brugia malayi haloacid dehalogenase-like hydrolase family protein 0.0056 0.022 0.1246
Trichomonas vaginalis conserved hypothetical protein 0.0018 0.0025 0.0156
Trichomonas vaginalis PIKK family atypical protein kinase 0.0026 0.0066 0.0518
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.004 0.0137 0.1151
Leishmania major target of rapamycin (TOR) kinase 2, putative 0.0045 0.0159 0.2006
Trichomonas vaginalis PIKK family atypical protein kinase 0.0045 0.0159 0.1343
Plasmodium vivax unspecified product 0.004 0.0137 0.1711
Echinococcus multilocularis thioredoxin glutathione reductase 0.0142 0.0656 0.1518
Brugia malayi hypothetical protein 0.0144 0.067 0.3799
Trichomonas vaginalis chromobox protein, putative 0.0035 0.0108 0.0887
Trypanosoma cruzi Phosphatidylinositol 3-kinase tor1 0.0045 0.0159 0.0228
Onchocerca volvulus Cathepsin F homolog 0.0056 0.022 0.1906
Loa Loa (eye worm) hypothetical protein 0.0026 0.0065 0.037
Brugia malayi cathepsin L-like precursor 0.0034 0.0107 0.0609
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0056 0.022 0.1881
Trichomonas vaginalis alpha-galactosidase/alpha-N-acetylgalactosaminidase, putative 0.0068 0.0278 0.2393
Echinococcus granulosus Ankyrin 0.0014 0.0005 0.0001
Echinococcus granulosus Niemann Pick C1 protein 0.0098 0.0431 0.0994
Schistosoma mansoni rab6-interacting 0.002 0.0031 0.0063
Schistosoma mansoni cation-transporting atpase worm 0.0032 0.0093 0.0207
Echinococcus multilocularis Glycoside hydrolase, family 27 0.0102 0.0451 0.1041
Toxoplasma gondii pyruvate dehydrogenase complex subunit PDH-E3II 0.0049 0.0182 0.0642
Echinococcus multilocularis phosphoserine phosphatase 0.002 0.0033 0.0069
Trypanosoma brucei vacuolar-type Ca2+-ATPase, putative 0.011 0.0496 0.6464
Plasmodium falciparum cysteine proteinase falcipain 1 0.004 0.0137 0.1711
Brugia malayi Peroxidasin 0.0026 0.0062 0.0354
Echinococcus granulosus cathepsin l1 0.0034 0.0107 0.0241
Mycobacterium ulcerans DNA polymerase IV 0.0138 0.0636 0.0625
Loa Loa (eye worm) hypothetical protein 0.0032 0.0093 0.0526
Onchocerca volvulus 0.002 0.0031 0.0239
Onchocerca volvulus Peroxidasin homolog 0.0026 0.0062 0.0517
Trypanosoma brucei vacuolar-type Ca2+-ATPase 1 0.011 0.0496 0.6464
Onchocerca volvulus Heterochromatin protein 1 homolog 0.0091 0.0396 0.3458
Echinococcus multilocularis phosphoserine phosphatase 0.002 0.0033 0.0069
Loa Loa (eye worm) ATP-dependent DNA helicase 0.0019 0.0029 0.0162
Brugia malayi Calcitonin receptor-like protein seb-1 0.0049 0.0181 0.1028
Brugia malayi alpha keto acid dehydrogenase complex, E3 component, lipoamide dehydrogenase 0.0036 0.0115 0.0654
Brugia malayi Phosphatidylinositol 3- and 4-kinase family protein 0.0015 0.0007 0.0042
Trichomonas vaginalis conserved hypothetical protein 0.0042 0.0145 0.1222
Toxoplasma gondii haloacid dehalogenase family hydrolase domain-containing protein 0.002 0.0033 0.0104
Brugia malayi potential phospholipid-transporting ATPase IIB, putative 0.0032 0.0093 0.0526
Mycobacterium ulcerans 4'-phosphopantetheinyl transferase 0.0023 0.005 0.0038
Brugia malayi Niemann-Pick C1 protein precursor 0.0098 0.0431 0.2441
Loa Loa (eye worm) hypothetical protein 0.0121 0.0553 0.3133
Trypanosoma brucei FAT domain/Rapamycin binding domain/Phosphatidylinositol 3- and 4-kinase, putative 0.0019 0.0026 0.0241
Echinococcus multilocularis calcium transporting ATPase type 2C member 0.0147 0.0682 0.1579
Echinococcus multilocularis mitogen activated protein kinase 0.0051 0.019 0.0432
Entamoeba histolytica myb-like DNA-binding domain containing protein 0.0048 0.0175 0.2328
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0056 0.022 0.1881
Loa Loa (eye worm) Smad1 0.0024 0.0056 0.0316
Trichomonas vaginalis PIKK family atypical protein kinase 0.0035 0.0112 0.0929
Leishmania major DNA polymerase kappa, putative 0.0035 0.0108 0.1327
Echinococcus multilocularis cathepsin L 0.0018 0.0025 0.0049
Loa Loa (eye worm) hypothetical protein 0.0026 0.0062 0.0354
Echinococcus granulosus GPCR family 2 0.0015 0.001 0.0015
Trichomonas vaginalis PIKK family atypical protein kinase 0.0035 0.0112 0.0929
Trichomonas vaginalis chromobox protein, putative 0.0153 0.0715 0.6265
Echinococcus multilocularis smad 0.0024 0.0056 0.0121
Brugia malayi Bloom's syndrome protein homolog 0.0046 0.0168 0.0949
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0034 0.0107 0.0886
Loa Loa (eye worm) papain family cysteine protease containing protein 0.0018 0.0025 0.0142
Trypanosoma brucei DNA polymerase kappa, putative 0.0118 0.0534 0.697
Loa Loa (eye worm) MH2 domain-containing protein 0.0024 0.0056 0.0316
Brugia malayi Pre-SET motif family protein 0.003 0.0086 0.0485
Onchocerca volvulus 0.0056 0.022 0.1906
Entamoeba histolytica chromodomain-helicase-DNA-binding protein, putative 0.0035 0.0108 0.128
Loa Loa (eye worm) hypothetical protein 0.0026 0.0062 0.0354
Trypanosoma brucei chrX additional, unordered contigs 0.0035 0.0108 0.1327
Loa Loa (eye worm) hypothetical protein 0.0035 0.0108 0.061
Schistosoma mansoni cathepsin F (C01 family) 0.0056 0.022 0.0503
Schistosoma mansoni atpase class VI type 11c 0.002 0.0033 0.0069
Brugia malayi Papain family cysteine protease containing protein 0.0018 0.0025 0.0142
Trypanosoma cruzi trypanothione reductase, putative 0.0142 0.0656 0.0976
Trypanosoma brucei phosphatidylinositol 4-kinase, putative 0.0045 0.0159 0.2006
Loa Loa (eye worm) hypothetical protein 0.0121 0.0553 0.3133
Plasmodium vivax SET domain protein, putative 0.003 0.0086 0.0923
Echinococcus multilocularis chromobox protein 1 0.0153 0.0715 0.1655
Plasmodium vivax copper-transporting ATPase, putative 0.0032 0.0093 0.1031
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0041 0.0141 0.118
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.0018 0.0025 0.0049
Entamoeba histolytica Plasma membrane calcium-transporting ATPase, putative 0.011 0.0496 0.7298
Mycobacterium leprae Probable metal cation-transporting P-type ATPase C CtpC 0.0032 0.0093 0.0061
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0056 0.022 0.1881
Brugia malayi Intermediate filament tail domain containing protein 0.0027 0.0068 0.0384
Schistosoma mansoni alpha-galactosidase/alpha-n-acetylgalactosaminidase 0.0014 0.0005 0.0001
Schistosoma mansoni hypothetical protein 0.0023 0.0049 0.0105
Onchocerca volvulus 0.0048 0.0176 0.1517
Schistosoma mansoni hypothetical protein 0.0286 0.1394 0.3235
Echinococcus multilocularis phosphatidylinositol 3 and 4 kinase 0.0015 0.0007 0.0008
Entamoeba histolytica hypothetical protein 0.0144 0.067 1
Schistosoma mansoni loxhd1 0.002 0.0031 0.0063
Plasmodium falciparum glutathione reductase 0.0142 0.0656 0.9602
Mycobacterium tuberculosis Probable metal cation transporter ATPase P-type CtpE 0.0032 0.0093 0.0061
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0056 0.022 0.1881
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0056 0.022 0.1881
Loa Loa (eye worm) hypothetical protein 0.0026 0.0062 0.0354
Echinococcus multilocularis dna polymerase kappa 0.0138 0.0636 0.1471
Giardia lamblia Phospholipid-transporting ATPase IA, putative 0.0032 0.0093 0.1331
Echinococcus multilocularis neuropeptide receptor A26 0.0465 0.2311 0.537
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.015 0.0698 0.9132
Chlamydia trachomatis phosphoshikimate 1-carboxyl vinyltransferase 0.0554 0.277 0.2733
Toxoplasma gondii BRCA1 C Terminus (BRCT) domain-containing protein 0.0041 0.0141 0.0495
Toxoplasma gondii 'chromo' (CHRromatin Organization MOdifier) domain-containing protein 0.0035 0.0108 0.0373
Mycobacterium ulcerans cation-transporter ATPase I CtpI 0.0068 0.0279 0.0268
Echinococcus granulosus lamin dm0 0.0027 0.0068 0.0149
Trypanosoma brucei unspecified product 0.0077 0.0324 0.4187
Trichomonas vaginalis r2r3-MYB transcription factor, putative 0.0048 0.0175 0.1486
Loa Loa (eye worm) hypothetical protein 0.0062 0.025 0.1417
Trypanosoma cruzi dihydrolipoyl dehydrogenase, putative 0.0049 0.0182 0.0263
Trichomonas vaginalis PIKK family atypical protein kinase 0.0033 0.0101 0.0825
Entamoeba histolytica cysteine protease, putative 0.004 0.0137 0.1742
Brugia malayi Associated with TFs and helicases family protein 0.0035 0.0108 0.061
Brugia malayi Pre-SET motif family protein 0.0207 0.0991 0.5614
Echinococcus granulosus histone lysine methyltransferase setb 0.003 0.0086 0.019
Loa Loa (eye worm) hypothetical protein 0.0026 0.0062 0.0354
Trichomonas vaginalis chromobox protein, putative 0.0035 0.0108 0.0887
Echinococcus multilocularis Tetracycline resistance leader peptide, TetL 0.011 0.0496 0.1146
Plasmodium vivax vivapain-3 0.004 0.0137 0.1711
Schistosoma mansoni SmCL2-like peptidase (C01 family) 0.004 0.0137 0.0311
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0018 0.0025 0.0156
Loa Loa (eye worm) latrophilin receptor protein 2 0.0015 0.001 0.0058
Toxoplasma gondii thioredoxin reductase 0.0142 0.0656 0.2356
Loa Loa (eye worm) hypothetical protein 0.002 0.0031 0.0176
Leishmania major target of rapamycin kinase (TOR) kinase 3 0.0035 0.0113 0.1391
Brugia malayi intermediate filament protein 0.0027 0.0068 0.0384
Brugia malayi hypothetical protein 0.0124 0.0565 0.3199
Onchocerca volvulus Cathepsin L homolog 0.0018 0.0025 0.0186
Toxoplasma gondii histone lysine methyltransferase SET/SUV39 0.003 0.0086 0.0293
Onchocerca volvulus 0.0056 0.022 0.1906
Loa Loa (eye worm) hypothetical protein 0.0035 0.0108 0.061
Leishmania major cathepsin L-like protease 0.0056 0.022 0.2811
Schistosoma mansoni serine/threonine protein kinase 0.0051 0.019 0.0432
Echinococcus granulosus cathepsin b 0.0018 0.0025 0.0049
Trichomonas vaginalis cation-transporting ATPase, putative 0.0064 0.0257 0.2213
Toxoplasma gondii haloacid dehalogenase family hydrolase domain-containing protein 0.0032 0.0093 0.0319
Giardia lamblia Sgs1 DNA helicase, putative 0.0019 0.0029 0.007
Entamoeba histolytica hypothetical protein 0.0144 0.067 1
Entamoeba histolytica cysteine proteinase, putative 0.0056 0.022 0.3019
Echinococcus multilocularis Ataxin 2, N terminal,domain containing protein 0.0023 0.0049 0.0105
Schistosoma mansoni cathepsin s 0.0022 0.0043 0.0092
Plasmodium vivax unspecified product 0.0022 0.0043 0.0278
Trichomonas vaginalis cation-transporting ATPase fungi, putative 0.011 0.0496 0.4326
Echinococcus granulosus tumor protein p63 0.0335 0.1646 0.3824
Brugia malayi Animal haem peroxidase family protein 0.0026 0.0062 0.0354
Schistosoma mansoni hypothetical protein 0.0035 0.0108 0.0242
Schistosoma mansoni alpha-galactosidase/alpha-n-acetylgalactosaminidase 0.0102 0.0451 0.1041
Trichomonas vaginalis plasma membrane calcium-transporting ATPase, putative 0.009 0.0394 0.3419
Loa Loa (eye worm) calcium ATPase 0.0067 0.0272 0.1541
Loa Loa (eye worm) ctsf protein 0.0056 0.022 0.1246
Trichomonas vaginalis CMGC family protein kinase 0.0051 0.019 0.1613
Loa Loa (eye worm) hypothetical protein 0.0049 0.0182 0.1031
Schistosoma mansoni alpha-galactosidase/alpha-n-acetylgalactosaminidase 0.0068 0.0278 0.0637
Brugia malayi MAP kinase sur-1 0.0051 0.019 0.1074
Mycobacterium tuberculosis Possible metal cation transporting P-type ATPase CtpH 0.0068 0.0279 0.0323
Mycobacterium ulcerans metal cation transporter ATPase p-type CtpE 0.0032 0.0093 0.0082
Loa Loa (eye worm) pre-SET domain-containing protein family protein 0.0207 0.0991 0.5614
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.0018 0.0025 0.0049
Leishmania major cathepsin L-like protease 0.015 0.0698 0.9132
Loa Loa (eye worm) pigment dispersing factor receptor c 0.0049 0.0181 0.1028
Trypanosoma cruzi cysteine proteinase, putative 0.004 0.0137 0.0196
Plasmodium falciparum calcium-transporting ATPase 0.0127 0.058 0.8441
Schistosoma mansoni retinoblastoma-binding protein 4 (rbbp4) 0.0014 0.0005 0.0001
Loa Loa (eye worm) hypothetical protein 0.0143 0.0663 0.3758
Echinococcus multilocularis cation transporting atpase worm 0.0032 0.0093 0.0207
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.015 0.0698 0.9132
Trichomonas vaginalis PIKK family atypical protein kinase 0.0033 0.0101 0.0825
Trypanosoma brucei phosphatidylinositol 3-kinase tor, putative 0.0021 0.0039 0.0415
Loa Loa (eye worm) hypothetical protein 0.0026 0.0062 0.0354
Echinococcus multilocularis cathepsin l cysteine peptidase 0.0056 0.022 0.0503
Echinococcus granulosus cathepsin L cysteine protease 0.004 0.0137 0.0311
Leishmania major cathepsin L-like protease 0.0056 0.022 0.2811
Toxoplasma gondii ATP-dependent DNA helicase, RecQ family protein 0.0019 0.0029 0.0087
Trichomonas vaginalis PIKK family atypical protein kinase 0.0027 0.0067 0.053
Echinococcus multilocularis phosphoserine phosphatase 0.002 0.0033 0.0069
Brugia malayi Animal haem peroxidase family protein 0.0026 0.0062 0.0354
Brugia malayi cathepsin Z-like cysteine proteinase 0.0018 0.0025 0.0142
Onchocerca volvulus 0.0056 0.022 0.1906
Entamoeba histolytica hypothetical protein 0.0035 0.0108 0.128
Brugia malayi Cathepsin L-like precursor 0.0056 0.022 0.1246
Brugia malayi CHD4 protein 0.0036 0.0116 0.0657
Leishmania major target of rapamycin (TOR) kinase 1, putative 0.0045 0.0159 0.2006
Echinococcus granulosus X box binding protein 1 0.0286 0.1394 0.3235
Toxoplasma gondii ATP-dependent DNA helicase, RecQ family protein 0.0031 0.0089 0.0306
Schistosoma mansoni hypothetical protein 0.0015 0.001 0.0015
Loa Loa (eye worm) hypothetical protein 0.0051 0.0194 0.1097
Echinococcus multilocularis calcium transporting atpase 0.0127 0.058 0.134
Schistosoma mansoni subfamily C1A unassigned peptidase (C01 family) 0.0018 0.0025 0.0049
Entamoeba histolytica hypothetical protein 0.0144 0.067 1
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.003 0.0086 0.019
Brugia malayi latrophilin 2 splice variant baaae 0.0033 0.0102 0.0579
Schistosoma mansoni cellular tumor antigen P53 0.0049 0.0182 0.0415
Toxoplasma gondii cathepsin CPC2 0.0018 0.0025 0.0074
Entamoeba histolytica plasma membrane calcium-transporting ATPase, putative 0.0022 0.0043 0.0271
Echinococcus granulosus Basic leucine zipper bZIP transcription factor 0.0081 0.0347 0.08
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0056 0.022 0.1881
Loa Loa (eye worm) hypothetical protein 0.0014 0.0005 0.0026
Echinococcus granulosus cathepsin l cysteine peptidase 0.0056 0.022 0.0503
Trypanosoma cruzi cysteine protease, putative 0.004 0.0137 0.0196
Leishmania major cathepsin L-like protease 0.0056 0.022 0.2811
Loa Loa (eye worm) hypothetical protein 0.0032 0.0093 0.0526
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0049 0.0182 0.0263
Entamoeba histolytica plasma membrane calcium ion-transporting ATPase, putative 0.0067 0.0272 0.3827
Trypanosoma brucei DNA polymerase kappa, putative 0.0138 0.0636 0.8313
Trypanosoma cruzi cysteine peptidase C (CPC), putative 0.0018 0.0025 0.0027
Echinococcus granulosus cysteine protease 0.004 0.0137 0.0311
Toxoplasma gondii glycosyl hydrolase, family 31 protein 0.0036 0.0114 0.0398
Brugia malayi E1-E2 ATPase family protein 0.0064 0.0257 0.1458
Trypanosoma cruzi hypothetical protein, conserved 0.0035 0.0108 0.0151
Echinococcus multilocularis tumor protein p63 0.0335 0.1646 0.3824
Echinococcus multilocularis cathepsin L 0.004 0.0137 0.0311
Echinococcus granulosus Chromo domain 0.0035 0.0108 0.0242
Loa Loa (eye worm) glutathione reductase 0.0142 0.0656 0.3717
Echinococcus multilocularis Chromo domain 0.0035 0.0108 0.0242
Leishmania major alpha glucosidase II subunit, putative 0.0036 0.0114 0.1416
Trypanosoma cruzi calcium-transporting ATPase, putative 0.0048 0.0177 0.0255
Echinococcus multilocularis histone lysine N methyltransferase SETMAR 0.003 0.0086 0.019
Brugia malayi Blistered cuticle protein 3 0.0026 0.0062 0.0354
Trichomonas vaginalis PIKK family atypical protein kinase 0.0035 0.0112 0.0929
Entamoeba histolytica cysteine protease, putative 0.004 0.0137 0.1742
Echinococcus multilocularis cadherin EGF LAG seven pass G type receptor 0.0015 0.001 0.0015
Loa Loa (eye worm) hypothetical protein 0.0026 0.0062 0.0354
Trypanosoma brucei Phosphatidylinositol 3-kinase tor1 0.0045 0.0159 0.2006
Schistosoma mansoni cation-transporting ATPase 0.0032 0.0093 0.0207
Giardia lamblia Myb 1-like protein 0.0048 0.0176 0.2973
Loa Loa (eye worm) hypothetical protein 0.0033 0.0102 0.0579
Trichomonas vaginalis pc-MYB2, putative 0.0048 0.0175 0.1486
Schistosoma mansoni chromobox protein 0.0035 0.0108 0.0242
Giardia lamblia Kinase, CMGC MAPK 0.0051 0.019 0.3232
Brugia malayi RNA recognition motif domain containing protein 0.0062 0.0249 0.1413
Echinococcus multilocularis cation transporting ATPase 13A3 0.0032 0.0093 0.0207
Trypanosoma brucei P-type H+-ATPase, putative 0.0064 0.0257 0.3306
Echinococcus multilocularis cathepsin b 0.0018 0.0025 0.0049
Trichomonas vaginalis PIKK family atypical protein kinase 0.0024 0.0054 0.0413
Loa Loa (eye worm) sodium/potassium-transporting ATPase subunit alpha 0.0068 0.0279 0.1583
Echinococcus granulosus cathepsin L 0.0018 0.0025 0.0049
Trichomonas vaginalis C-MYB, putative 0.0048 0.0175 0.1486
Trichomonas vaginalis PIKK family atypical protein kinase 0.0024 0.0054 0.0412
Echinococcus granulosus dnaJ subfamily B 0.0405 0.2007 0.4664
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0018 0.0025 0.0156
Trichomonas vaginalis Clan CA, family C1, cathepsin L or H-like cysteine peptidase 0.0018 0.0025 0.0156
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0018 0.0025 0.0156
Brugia malayi Cathepsin L-like precursor 0.0056 0.022 0.1246
Mycobacterium tuberculosis NADPH-dependent mycothiol reductase Mtr 0.0142 0.0656 0.0852
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0018 0.0025 0.0156
Trichomonas vaginalis PIKK family atypical protein kinase 0.0033 0.0101 0.0825
Echinococcus multilocularis phosphoserine phosphatase 0.002 0.0033 0.0069
Plasmodium falciparum ATP-dependent DNA helicase Q1 0.0019 0.0029 0.0054
Loa Loa (eye worm) cathepsin B 0.0018 0.0025 0.0142
Brugia malayi hypothetical protein 0.0121 0.0549 0.3111
Entamoeba histolytica hypothetical protein 0.0144 0.067 1
Echinococcus granulosus Ankyrin repeat domain containing protein 0.0089 0.0387 0.0892
Loa Loa (eye worm) papain family cysteine protease containing protein 0.0056 0.022 0.1246
Schistosoma mansoni alpha-galactosidase/alpha-n-acetylgalactosaminidase 0.0102 0.0451 0.1041
Mycobacterium leprae PROBABLE UDP-N-ACETYLGLUCOSAMINE 1-CARBOXYVINYLTRANSFERASE MURA 0.1412 0.7161 1
Trypanosoma cruzi DNA polymerase eta, putative 0.0086 0.037 0.0546
Mycobacterium ulcerans DNA polymerase IV 0.0138 0.0636 0.0625
Echinococcus granulosus smad 0.0024 0.0056 0.0121
Echinococcus multilocularis cathepsin L cysteine protease 0.0056 0.022 0.0503
Schistosoma mansoni DNA helicase recq1 0.0019 0.0029 0.0057
Brugia malayi cathepsin F-like cysteine proteinase 0.0018 0.0025 0.0142
Brugia malayi Cathepsin L-like precursor 0.0034 0.0107 0.0609
Toxoplasma gondii phospholipid-translocating P-type ATPase, flippase subfamily protein 0.002 0.0033 0.0104
Leishmania major cysteine peptidase A (CPA) 0.0056 0.022 0.2811
Trichomonas vaginalis Clan CA, family C1, cathepsin L or K-like cysteine peptidase 0.0056 0.022 0.1881
Onchocerca volvulus Cathepsin L homolog 0.0056 0.022 0.1906
Echinococcus granulosus lysosomal alpha glucosidase 0.0161 0.0758 0.1756
Leishmania major mitogen activated protein kinase 4, putative;with=GeneDB:LmxM19.1440 0.0051 0.019 0.241
Loa Loa (eye worm) RNA binding protein 0.0062 0.0249 0.1413
Onchocerca volvulus 0.0236 0.1137 1
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0056 0.022 0.1881
Loa Loa (eye worm) hypothetical protein 0.0018 0.0025 0.0142
Schistosoma mansoni hypothetical protein 0.0051 0.0193 0.0441
Brugia malayi Cathepsin L-like precursor 0.0056 0.022 0.1246
Schistosoma mansoni lipoxygenase 0.002 0.0031 0.0063
Trichomonas vaginalis Heterochromatin protein, putative 0.0035 0.0108 0.0887
Leishmania major cytochrome p450-like protein 0.0016 0.0011 0.0052
Brugia malayi Cytochrome P450 family protein 0.0016 0.0011 0.0064
Leishmania major proton motive ATPase, putative 0.0032 0.0093 0.113
Mycobacterium tuberculosis Possible DNA-damage-inducible protein P DinP (DNA polymerase V) (pol IV 2) (DNA nucleotidyltransferase (DNA-directed)) 0.0118 0.0534 0.0681
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.015 0.0698 0.9132
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0018 0.0025 0.0156
Brugia malayi bZIP transcription factor family protein 0.0081 0.0347 0.1969
Trypanosoma brucei hypothetical protein, conserved 0.0023 0.005 0.0558
Entamoeba histolytica Plasma membrane calcium-transporting ATPase, putative 0.011 0.0496 0.7298
Schistosoma mansoni ATPase 0.0147 0.0682 0.1579
Loa Loa (eye worm) hypothetical protein 0.0124 0.0564 0.3196
Entamoeba histolytica Niemann-Pick C1 protein, putative 0.0098 0.0431 0.6287
Toxoplasma gondii heavy metal translocating P-type ATPase subfamily protein 0.0032 0.0093 0.0319
Loa Loa (eye worm) hypothetical protein 0.0068 0.0278 0.1574
Echinococcus multilocularis L aminoadipate semialdehyde 0.0082 0.0353 0.0813
Echinococcus granulosus chromobox protein 1 0.0153 0.0715 0.1655
Trichomonas vaginalis glutathione reductase, putative 0.0049 0.0182 0.1547
Trypanosoma brucei DNA polymerase IV, putative 0.0138 0.0636 0.8313
Schistosoma mansoni alpha-galactosidase/alpha-n-acetylgalactosaminidase 0.0068 0.0278 0.0637
Brugia malayi SET domain containing protein 0.0036 0.0116 0.066
Trichomonas vaginalis r2r3-MYB transcription factor, putative 0.0048 0.0175 0.1486
Toxoplasma gondii sarco/endoplasmic reticulum Ca2+-ATPase 0.0147 0.0682 0.245
Echinococcus multilocularis dihydrolipoamide dehydrogenase 0.0049 0.0182 0.0415
Entamoeba histolytica hypothetical protein 0.0035 0.0108 0.128
Brugia malayi Cathepsin L-like precursor 0.0056 0.022 0.1246
Schistosoma mansoni hypothetical protein 0.0853 0.43 1
Echinococcus multilocularis FKBP12 rapamycin complex associated protein 0.0045 0.0159 0.0361
Trypanosoma cruzi cytochrome P450, putative 0.0016 0.0011 0.0006
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0041 0.0141 0.118
Echinococcus granulosus terminal deoxycytidyl transferase rev1 0.0111 0.0501 0.1156
Toxoplasma gondii P-type ATPase PMA1 0.0064 0.0257 0.0914
Leishmania major P-type H -ATPase, putative 0.0064 0.0257 0.3306
Trichomonas vaginalis chromobox protein, putative 0.0153 0.0715 0.6265
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.004 0.0137 0.172
Entamoeba histolytica chromodomain-helicase-DNA-binding protein, putative 0.0035 0.0108 0.128
Brugia malayi Calcium-transporting ATPase sarcoplasmic/endoplasmic reticulum type 0.0127 0.058 0.3284
Giardia lamblia NADH oxidase lateral transfer candidate 0.0049 0.0182 0.3085
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0056 0.022 0.1881
Trypanosoma cruzi mitogen activated protein kinase 4, putative 0.0051 0.019 0.0274
Brugia malayi Papain family cysteine protease containing protein 0.0018 0.0025 0.0142
Schistosoma mansoni ankyrin 23/unc44 0.0014 0.0004 0.000000044333
Echinococcus granulosus tar DNA binding protein 0.0062 0.0249 0.0571
Loa Loa (eye worm) heterochromatin protein 1 0.0153 0.0715 0.4051
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0056 0.022 0.1881
Loa Loa (eye worm) ImpB/MucB/SamB family protein 0.0111 0.0501 0.2837
Trichomonas vaginalis ATPase, class I, type 8B, putative 0.0032 0.0093 0.0756
Plasmodium vivax hypothetical protein, conserved 0.0035 0.0108 0.1257
Echinococcus multilocularis jun protein 0.0081 0.0347 0.08
Brugia malayi Cathepsin L-like precursor 0.0022 0.0043 0.0245
Entamoeba histolytica deoxycytidyl transferase, putative 0.0111 0.0501 0.7371
Toxoplasma gondii shikimate dehydrogenase substrate binding domain-containing protein 0.0554 0.277 1
Echinococcus granulosus calcium transporting ATPase type 2C member 0.0147 0.0682 0.1579
Echinococcus granulosus cation transporting ATPase 13A3 0.0032 0.0093 0.0207
Trypanosoma brucei DNA polymerase kappa, putative 0.0138 0.0636 0.8313
Trypanosoma brucei cysteine peptidase C (CPC) 0.0018 0.0025 0.0233
Schistosoma mansoni DNA polymerase eta 0.0162 0.0763 0.1768
Onchocerca volvulus 0.0093 0.0409 0.3577
Echinococcus granulosus Ataxin 2 N terminaldomain containing protein 0.0023 0.0049 0.0105
Brugia malayi ATP-dependent DNA helicase, RecQ family protein 0.0019 0.0029 0.0162
Brugia malayi Na,K-ATPase alpha subunit 0.01 0.0444 0.2515
Onchocerca volvulus 0.0056 0.022 0.1906
Loa Loa (eye worm) calcium-transporting ATPase sarcoplasmic/endoplasmic reticulum type 0.0095 0.0415 0.2352
Mycobacterium tuberculosis Probable metal cation transporter P-type ATPase CtpV 0.0032 0.0093 0.0061
Trichomonas vaginalis conserved hypothetical protein 0.0035 0.0108 0.0887
Schistosoma mansoni smad1 5 8 and 0.0024 0.0056 0.0121
Trypanosoma cruzi phospholipid-transporting ATPase-like protein, putative 0.002 0.0033 0.0039
Trypanosoma cruzi trypanothione reductase, putative 0.0049 0.0182 0.0263
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.0018 0.0025 0.0049
Schistosoma mansoni calcium-transporting atpase sarcoplasmic/endoplasmic reticulum type (calcium pump) 0.0127 0.058 0.134
Echinococcus granulosus neuropeptide receptor A26 0.0465 0.2311 0.537
Echinococcus granulosus copper transporting ATPase 1 0.0032 0.0093 0.0207
Echinococcus granulosus lipoxygenase domain containing protein 0.002 0.0031 0.0063
Echinococcus multilocularis Chromobox protein 3 0.0035 0.0108 0.0242
Trichomonas vaginalis PIKK family atypical protein kinase 0.0024 0.0054 0.0413
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.015 0.0698 0.9132
Trichomonas vaginalis PIKK family atypical protein kinase 0.0027 0.0067 0.053
Echinococcus multilocularis histone lysine methyltransferase setb histone lysine methyltransferase eggless 0.003 0.0086 0.019
Schistosoma mansoni niemann-pick C1 (NPC1) 0.0099 0.0438 0.1012
Trichomonas vaginalis PIKK family atypical protein kinase 0.0033 0.0101 0.0825
Plasmodium falciparum dihydrolipoyl dehydrogenase, apicoplast 0.0049 0.0182 0.2391
Echinococcus granulosus peroxidasin 0.0026 0.0062 0.0136
Plasmodium vivax heterochromatin protein 1, putative 0.0035 0.0108 0.1257
Trypanosoma brucei vacuolar-type Ca2+-ATPase 2 0.011 0.0496 0.6464
Trypanosoma cruzi hypothetical protein, conserved 0.0036 0.0114 0.0161
Brugia malayi Probable cation-transporting ATPase C10C6.6 in chromosome IV 0.0032 0.0093 0.0526
Echinococcus granulosus cation transporting ATPase 13A1 0.0032 0.0093 0.0207
Loa Loa (eye worm) cysteine proteinase cathepsin Z 0.0018 0.0025 0.0142
Loa Loa (eye worm) hypothetical protein 0.0049 0.0181 0.1028
Schistosoma mansoni peroxidasin 0.0026 0.0062 0.0136
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0018 0.0025 0.0156
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0041 0.0141 0.118
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0056 0.022 0.1881
Plasmodium falciparum thioredoxin reductase 0.0049 0.0182 0.2391
Entamoeba histolytica cysteine protease, putative 0.004 0.0137 0.1742
Schistosoma mansoni microtubule-associated protein tau 0.0684 0.3434 0.7986
Schistosoma mansoni chromobox protein-related (chromobox 1) (heterochromatin 1) 0.0035 0.0108 0.0242
Trichomonas vaginalis plasma membrane calcium-transporting ATPase, putative 0.011 0.0496 0.4326
Plasmodium falciparum non-SERCA-type Ca2+ -transporting P-ATPase 0.0147 0.0682 1
Leishmania major trypanothione reductase 0.0142 0.0656 0.858
Plasmodium falciparum copper-transporting ATPase 0.0032 0.0093 0.1031
Wolbachia endosymbiont of Brugia malayi dihydrolipoamide dehydrogenase E3 component 0.0049 0.0182 0.0133
Onchocerca volvulus 0.0026 0.0062 0.0517
Trichomonas vaginalis DNA helicase recq, putative 0.0046 0.0168 0.1418
Brugia malayi Papain family cysteine protease containing protein 0.0056 0.022 0.1246
Brugia malayi Cathepsin L-like precursor 0.0056 0.022 0.1246
Trypanosoma cruzi cysteine peptidase C (CPC), putative 0.0018 0.0025 0.0027
Schistosoma mansoni intermediate filament proteins 0.0027 0.0068 0.0149
Schistosoma mansoni hypothetical protein 0.0405 0.2007 0.4664
Trichomonas vaginalis PIKK family atypical protein kinase 0.0033 0.0101 0.0825
Toxoplasma gondii histone lysine methyltransferase SET1 0.0055 0.0213 0.0753
Trypanosoma cruzi mitogen-activated protein kinase 11, putative 0.0051 0.019 0.0274
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0041 0.0141 0.118
Loa Loa (eye worm) transcription factor SMAD2 0.0358 0.1765 1
Trichomonas vaginalis CMGC family protein kinase 0.0051 0.019 0.1613
Schistosoma mansoni Smad4 0.0024 0.0056 0.0121
Trichomonas vaginalis Clan CA, family C1, cathepsin B-like cysteine peptidase 0.0018 0.0025 0.0156
Toxoplasma gondii ImpB/MucB/SamB family protein 0.0035 0.0108 0.0373
Plasmodium vivax DNA repair protein REV1, putative 0.0035 0.0108 0.1259
Echinococcus multilocularis Basic leucine zipper (bZIP) transcription 0.0144 0.067 0.1551
Schistosoma mansoni TGF-beta signal transducer Smad2 0.0024 0.0056 0.0121
Brugia malayi MH2 domain containing protein 0.0024 0.0056 0.0316
Loa Loa (eye worm) hypothetical protein 0.0022 0.0043 0.0245
Trichomonas vaginalis r2r3-MYB transcription factor, putative 0.0048 0.0176 0.1497
Brugia malayi Membrane calcium atpase protein 3 0.009 0.0394 0.223
Brugia malayi calcium ATPase 0.0047 0.017 0.0961
Brugia malayi cathepsin Z-like cysteine proteinase 0.0018 0.0025 0.0142
Loa Loa (eye worm) hypothetical protein 0.0035 0.0108 0.061
Entamoeba histolytica chromodomain-helicase-DNA-binding protein, putative 0.0035 0.0108 0.128
Schistosoma mansoni chromobox protein 0.0153 0.0715 0.1655
Giardia lamblia DNA damage repair protein 0.0035 0.0108 0.1625
Trypanosoma brucei calcium-transporting ATPase, putative 0.0048 0.0177 0.2242
Echinococcus multilocularis chromodomain helicase DNA binding protein 4 0.0036 0.0116 0.0261
Loa Loa (eye worm) hypothetical protein 0.0079 0.0334 0.189
Echinococcus granulosus cathepsin L 0.004 0.0137 0.0311
Loa Loa (eye worm) hypothetical protein 0.0018 0.0025 0.0142
Trichomonas vaginalis plasma membrane calcium-transporting ATPase, putative 0.011 0.0496 0.4326
Trypanosoma cruzi calcium-translocating P-type ATPase, putative 0.0083 0.0356 0.0524
Trichomonas vaginalis chromobox protein, putative 0.0097 0.0427 0.3713
Plasmodium vivax cation transporting ATPase, putative 0.0032 0.0093 0.1031
Toxoplasma gondii preprocathepsin c precursor, putative 0.0018 0.0025 0.0074
Loa Loa (eye worm) hypothetical protein 0.0026 0.0062 0.0354
Trypanosoma brucei trypanothione reductase 0.0142 0.0656 0.858
Brugia malayi ImpB/MucB/SamB family protein 0.0162 0.0763 0.4325
Trypanosoma cruzi plasma membrane Ca2+ ATPase 0.011 0.0496 0.0735
Brugia malayi MH1 domain containing protein 0.0024 0.0056 0.0316
Trichomonas vaginalis alpha-glucosidase, putative 0.0036 0.0114 0.0948
Loa Loa (eye worm) hypothetical protein 0.0061 0.0243 0.1376
Entamoeba histolytica plasma membrane calcium-transporting ATPase 1, putative 0.0067 0.0272 0.3827
Brugia malayi Protein kinase domain containing protein 0.0015 0.0006 0.0035
Echinococcus granulosus Alpha N acetylgalactosaminidase 0.0102 0.0451 0.1041
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0056 0.022 0.1881
Loa Loa (eye worm) hypothetical protein 0.0018 0.0025 0.0142
Brugia malayi ImpB/MucB/SamB family protein 0.0111 0.0501 0.2837
Echinococcus multilocularis diuretic hormone 44 receptor GPRdih2 0.0015 0.001 0.0015
Brugia malayi Uncoordinated protein 44 0.0014 0.0004 0.0022
Plasmodium vivax dihydrolipoyl dehydrogenase, apicoplast, putative 0.0049 0.0182 0.2391
Wolbachia endosymbiont of Brugia malayi UDP-N-acetylglucosamine 1-carboxyvinyltransferase 0.1966 1 1
Loa Loa (eye worm) hypothetical protein 0.003 0.0086 0.0485
Mycobacterium leprae probable 3-phosphoshikimate 1-carboxyvinyl transferase AroA (5-ENOLPYRUVYLSHIKIMATE-3-PHOSPHATE SYNTHASE) (EPSP SYNTHASE) (EPSPS 0.0554 0.277 0.3824
Leishmania major cysteine peptidase C (CPC),CPC cysteine peptidase, Clan CA, family C1, Cathepsin B-like 0.0018 0.0025 0.0233
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0056 0.022 0.1881
Echinococcus granulosus bloom syndrome protein 0.0046 0.0168 0.0381
Echinococcus multilocularis cation transporting ATPase 13A1 0.0032 0.0093 0.0207
Echinococcus granulosus arachidonate 5 lipoxygenase 0.0055 0.0211 0.0483
Plasmodium falciparum ataxin-2 like protein, putative 0.0051 0.0194 0.2577
Leishmania major dihydrolipoamide dehydrogenase, putative 0.0049 0.0182 0.2312
Loa Loa (eye worm) hypothetical protein 0.0056 0.022 0.1246
Echinococcus granulosus phospholipid transporting ATPase IIB 0.0032 0.0093 0.0207
Onchocerca volvulus Cathepsin L homolog 0.0056 0.022 0.1906
Toxoplasma gondii chromodomain helicase DNA binding protein CHD1/SWI2/SNF2 0.0035 0.0108 0.0373
Schistosoma mansoni rab geranylgeranyl transferase alpha subunit 0.0111 0.0501 0.1156
Trypanosoma cruzi DNA polymerase eta, putative 0.0162 0.0763 0.1138
Mycobacterium tuberculosis Probable reductase 0.0323 0.1585 0.2158
Brugia malayi Animal haem peroxidase family protein 0.0026 0.0062 0.0354
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0041 0.0141 0.118
Plasmodium vivax glutathione reductase, putative 0.0142 0.0656 0.9602
Trypanosoma cruzi copper-transporting ATPase-like protein, putative 0.002 0.0033 0.0039
Schistosoma mansoni plasma membrane calcium-transporting atpase 0.009 0.0394 0.0907
Schistosoma mansoni rab6-interacting 0.002 0.0031 0.0063
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.004 0.0137 0.172
Trichomonas vaginalis conserved hypothetical protein 0.0038 0.0125 0.1044
Loa Loa (eye worm) hypothetical protein 0.0162 0.0763 0.4325
Toxoplasma gondii target of rapamycin (TOR), putative 0.0033 0.0101 0.0348
Trypanosoma brucei calcium-translocating P-type ATPase 0.0127 0.058 0.757
Toxoplasma gondii plasma membrane-type Ca(2+)-ATPase A1 PMCAA1 0.009 0.0394 0.1407
Schistosoma mansoni blooms syndrome DNA helicase 0.0036 0.0118 0.0265
Trichomonas vaginalis conserved hypothetical protein 0.0035 0.0108 0.0887
Echinococcus multilocularis GPCR, family 2 0.0015 0.001 0.0015
Entamoeba histolytica cysteine protease, putative 0.004 0.0137 0.1742
Schistosoma mansoni hypothetical protein 0.002 0.0031 0.0063
Trypanosoma cruzi proton motive ATPase 1, putative 0.002 0.0033 0.0039
Echinococcus granulosus TGF beta signal transducer SmadC 0.0024 0.0056 0.0121
Schistosoma mansoni SmCL2-like peptidase (C01 family) 0.004 0.0137 0.0311
Brugia malayi Latrophilin receptor protein 2 0.0015 0.001 0.0058
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.003 0.0086 0.019
Schistosoma mansoni survival motor neuron protein 0.0048 0.0176 0.04
Mycobacterium tuberculosis Probable membrane NADH dehydrogenase NdhA 0.0323 0.1585 0.2158
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.015 0.0698 0.9132
Schistosoma mansoni alpha-galactosidase/alpha-n-acetylgalactosaminidase 0.0102 0.0451 0.1041
Schistosoma mansoni multiple ankyrin repeats single kh domain protein 0.0089 0.0387 0.0892
Trichomonas vaginalis Clan CA, family C1, cathepsin H-like cysteine peptidase 0.0018 0.0025 0.0156
Echinococcus granulosus survival motor neuron protein 1 0.0234 0.1131 0.2625
Onchocerca volvulus 0.0124 0.0564 0.4941
Trypanosoma cruzi cysteine peptidase, putative 0.015 0.0698 0.1039
Schistosoma mansoni chromobox protein 0.0153 0.0715 0.1655
Echinococcus multilocularis RUN 0.002 0.0031 0.0063
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0041 0.0141 0.118
Echinococcus granulosus phospholipid transporting ATPase VA 0.002 0.0033 0.0069
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0049 0.0182 0.0263
Echinococcus granulosus 5'partial|histone lysine N methyltransferase SETDB2 0.0028 0.0077 0.017
Echinococcus multilocularis Niemann Pick C1 protein 0.0139 0.0645 0.1493
Onchocerca volvulus Dual oxidase homolog 0.0026 0.0062 0.0517
Trichomonas vaginalis PIKK family atypical protein kinase 0.0024 0.0054 0.0412
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0038 0.0125 0.1044
Loa Loa (eye worm) CXXC zinc finger family protein 0.0028 0.0077 0.0435
Brugia malayi calcium ATPase 0.0044 0.0155 0.0878
Plasmodium vivax vivapain-2 0.0056 0.022 0.2966
Schistosoma mansoni copper ABC transporter ATPase 0.0032 0.0093 0.0207
Loa Loa (eye worm) phosphatidylinositol 3 0.0015 0.0007 0.0042
Echinococcus multilocularis sterol regulatory element binding protein 0.0042 0.0145 0.0329
Trypanosoma brucei target of rapamycin kinase 3, putative 0.0035 0.0113 0.1391
Trypanosoma brucei DNA polymerase kappa, putative 0.0083 0.0357 0.463
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0061 0.0246 0.0563
Trichomonas vaginalis neutral alpha-glucosidase ab precursor, putative 0.0036 0.0114 0.0948
Loa Loa (eye worm) hypothetical protein 0.0032 0.0095 0.0541
Leishmania major copper-transporting ATPase-like protein, putative 0.0032 0.0093 0.113
Trichomonas vaginalis PIKK family atypical protein kinase 0.0024 0.0054 0.0412
Loa Loa (eye worm) hypothetical protein 0.0022 0.0043 0.0245
Loa Loa (eye worm) animal heme peroxidase 0.0026 0.0062 0.0354
Entamoeba histolytica FKBP-rapamycin associated protein (FRAP), putative 0.0045 0.0159 0.2077
Schistosoma mansoni hypothetical protein 0.0066 0.0269 0.0618
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0018 0.0025 0.0156
Toxoplasma gondii E1-E2 ATPase subfamily protein 0.0044 0.0155 0.0544
Onchocerca volvulus Huntingtin homolog 0.0121 0.0553 0.4844
Schistosoma mansoni peroxidasin 0.0026 0.0062 0.0136
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.0018 0.0025 0.0049
Onchocerca volvulus Huntingtin homolog 0.0121 0.0553 0.4844
Trichomonas vaginalis alpha-glucosidase, putative 0.0036 0.0114 0.0948
Mycobacterium ulcerans 3-phosphoshikimate 1-carboxyvinyltransferase 0.0554 0.277 0.2761
Schistosoma mansoni jun-related protein 0.0066 0.0269 0.0618
Brugia malayi CXXC zinc finger family protein 0.0028 0.0077 0.0435
Brugia malayi calcium-independent alpha-latrotoxin receptor 2, putative 0.0015 0.001 0.0058
Brugia malayi chromobox protein homolog 3 0.0091 0.0396 0.2243
Brugia malayi cathepsin B-like cysteine proteinase 0.0018 0.0025 0.0142
Trypanosoma cruzi copper-transporting ATPase-like protein, putative 0.0032 0.0093 0.0128
Trypanosoma brucei P-type H+-ATPase, putative 0.0064 0.0257 0.3306
Toxoplasma gondii cathepsin CPC1 0.0018 0.0025 0.0074
Loa Loa (eye worm) hypothetical protein 0.0091 0.0396 0.2243
Schistosoma mansoni subfamily C1A non-peptidase homologue (C01 family) 0.0018 0.0025 0.0049
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0049 0.0182 0.0263
Entamoeba histolytica phospholipid-transporting P-type ATPase, putative 0.0032 0.0093 0.105
Schistosoma mansoni chromodomain helicase DNA binding protein 0.0036 0.0116 0.0261
Echinococcus multilocularis Niemann Pick C1 protein 0.0098 0.0431 0.0994
Trypanosoma cruzi copper-transporting ATPase-like protein, putative 0.0032 0.0093 0.0128
Trypanosoma brucei unspecified product 0.0077 0.0324 0.4187
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.0018 0.0025 0.0049
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0035 0.0108 0.0887
Echinococcus multilocularis ankyrin repeat and death domain containing protein 0.0014 0.0004 0.000000044333
Echinococcus granulosus Protein patched homolog 1 0.0042 0.0145 0.0329
Schistosoma mansoni cathepsin F (C01 family) 0.0034 0.0107 0.0241
Echinococcus multilocularis Smad4 0.0024 0.0056 0.0121
Brugia malayi Papain family cysteine protease containing protein 0.004 0.0137 0.0779
Trichomonas vaginalis PIKK family atypical protein kinase 0.0038 0.0126 0.1047
Echinococcus granulosus chromobox protein 1 0.0153 0.0715 0.1655
Echinococcus granulosus cathepsin l1 0.0056 0.022 0.0503
Entamoeba histolytica cysteine proteinase, putative 0.0056 0.022 0.3019
Entamoeba histolytica cysteine proteinase 2 0.004 0.0137 0.1742
Brugia malayi Cathepsin L-like precursor 0.0034 0.0107 0.0609
Loa Loa (eye worm) hypothetical protein 0.0032 0.0093 0.0526
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0056 0.022 0.1881
Loa Loa (eye worm) hypothetical protein 0.002 0.0031 0.0176
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0056 0.022 0.1881
Trypanosoma brucei DNA polymerase kappa, putative 0.0138 0.0636 0.8313
Echinococcus multilocularis peroxidasin 0.0026 0.0062 0.0136
Loa Loa (eye worm) hypothetical protein 0.0314 0.1542 0.8736
Schistosoma mansoni tar DNA-binding protein 0.0062 0.0249 0.0571
Trichomonas vaginalis set domain proteins, putative 0.0235 0.1137 1
Schistosoma mansoni type V p-type atpase isoform 0.0032 0.0093 0.0207
Echinococcus multilocularis phospholipid transporting ATPase VA 0.002 0.0033 0.0069
Loa Loa (eye worm) hypothetical protein 0.0034 0.0107 0.0609
Brugia malayi Phosphatidylinositol 3- and 4-kinase family protein 0.0045 0.0159 0.0901
Loa Loa (eye worm) hypothetical protein 0.0018 0.0025 0.0142
Toxoplasma gondii melibiase subfamily protein 0.0102 0.0451 0.1614
Brugia malayi Cathepsin L-like cysteine proteinase 0.0034 0.0107 0.0609
Echinococcus granulosus cadherin EGF LAG seven pass G type receptor 0.0015 0.001 0.0015
Onchocerca volvulus 0.0056 0.022 0.1906
Echinococcus granulosus chromodomain helicase DNA binding protein 4 0.0036 0.0116 0.0261
Toxoplasma gondii 'chromo' (CHRromatin Organization MOdifier) domain-containing protein 0.0035 0.0108 0.0373
Trypanosoma cruzi major cysteine proteinase, putative 0.0018 0.0025 0.0027
Mycobacterium tuberculosis NAD(P)H quinone reductase LpdA 0.0359 0.1769 0.2418
Plasmodium falciparum cysteine proteinase falcipain 2a 0.0056 0.022 0.2966
Schistosoma mansoni hypothetical protein 0.004 0.0138 0.0311
Leishmania major vacuolar-type Ca2 -ATPase, putative 0.011 0.0496 0.6464
Schistosoma mansoni cpg binding protein 0.0028 0.0077 0.017
Echinococcus granulosus Niemann Pick C1 protein 0.0139 0.0645 0.1493
Loa Loa (eye worm) thioredoxin reductase 0.0142 0.0656 0.3717
Trypanosoma cruzi major cysteine proteinase, putative 0.0112 0.0503 0.0746
Echinococcus granulosus diuretic hormone 44 receptor GPRdih2 0.0015 0.001 0.0015
Mycobacterium leprae PROBABLE NADH DEHYDROGENASE NDH 0.0323 0.1585 0.2158
Trichomonas vaginalis neutral alpha-glucosidase ab precursor, putative 0.0036 0.0114 0.0948
Brugia malayi Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain containing protein 0.0036 0.0115 0.0654
Brugia malayi Cytochrome P450 family protein 0.0016 0.0011 0.0064
Brugia malayi Iron-sulfur cluster assembly accessory protein 0.0048 0.0176 0.0996
Trichomonas vaginalis MYB, putative 0.0048 0.0176 0.1497
Trichomonas vaginalis CMGC family protein kinase 0.0051 0.019 0.1613
Loa Loa (eye worm) blistered cuticle protein 3 0.0026 0.0062 0.0354
Loa Loa (eye worm) animal heme peroxidase 0.0026 0.0062 0.0354
Entamoeba histolytica cysteine protease, putative 0.004 0.0137 0.1742
Trichomonas vaginalis mercuric reductase, putative 0.0049 0.0182 0.1547
Entamoeba histolytica cysteine protease, putative 0.004 0.0137 0.1742
Echinococcus multilocularis Ca2+ transporting ATPase plasma membrane 0.009 0.0394 0.0907
Trichomonas vaginalis r2r3-MYB transcription factor, putative 0.0048 0.0175 0.1486
Trichomonas vaginalis r2r3-MYB transcription factor, putative 0.0048 0.0175 0.1486
Echinococcus granulosus thioredoxin glutathione reductase 0.0142 0.0656 0.1518
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.015 0.0698 0.9132
Onchocerca volvulus 0.002 0.0031 0.0239
Trichomonas vaginalis hypothetical protein 0.0035 0.0108 0.0887
Entamoeba histolytica cysteine proteinase, putative 0.004 0.0137 0.1742
Leishmania major P-type ATPase, putative 0.009 0.0394 0.5109
Trypanosoma cruzi target of rapamycin kinase 3 0.0035 0.0113 0.0158
Onchocerca volvulus 0.0065 0.0262 0.2281
Leishmania major DNA polymerase kappa, putative,DNA polymerase IV, putative 0.0118 0.0534 0.697
Plasmodium falciparum thioredoxin reductase 0.0142 0.0656 0.9602
Onchocerca volvulus 0.0056 0.022 0.1906
Loa Loa (eye worm) papain family cysteine protease containing protein 0.0022 0.0043 0.0245
Toxoplasma gondii 4'-phosphopantetheinyl transferase domain-containing protein 0.0023 0.005 0.0163
Trypanosoma brucei DNA polymerase eta, putative 0.0162 0.0763 1
Onchocerca volvulus 0.0027 0.0068 0.0564
Schistosoma mansoni alpha-galactosidase/alpha-n-acetylgalactosaminidase 0.0102 0.0451 0.1041
Echinococcus granulosus intermediate filament protein 0.0027 0.0068 0.0149
Echinococcus multilocularis dnaJ subfamily B 0.0405 0.2007 0.4664
Trichomonas vaginalis DNA polymerase IV / kappa, putative 0.0138 0.0636 0.5564
Mycobacterium tuberculosis Probable soluble pyridine nucleotide transhydrogenase SthA (STH) (NAD(P)(+) transhydrogenase [B-specific]) (nicotinamide nucleot 0.0049 0.0182 0.0186
Trichomonas vaginalis phospholipid-transporting ATPase, putative 0.0032 0.0093 0.0756
Echinococcus multilocularis expressed conserved protein 0.0092 0.04 0.0923
Brugia malayi CHE-14 protein 0.0042 0.0145 0.0824
Echinococcus multilocularis survival motor neuron protein 1 0.0234 0.1131 0.2625
Leishmania major cathepsin L-like protease 0.015 0.0698 0.9132
Trypanosoma brucei DNA polymerase kappa, putative 0.0061 0.0243 0.3114
Echinococcus granulosus Basic leucine zipper bZIP transcription 0.0144 0.067 0.1551
Trypanosoma brucei protein kinase, putative 0.0051 0.019 0.241
Trypanosoma cruzi cruzipain precursor, putative 0.1312 0.6651 1
Trichomonas vaginalis PIKK family atypical protein kinase 0.0024 0.0054 0.0413
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0056 0.022 0.1881
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.0018 0.0025 0.0049
Trypanosoma brucei glucosidase, putative 0.0036 0.0114 0.1416
Schistosoma mansoni tar DNA-binding protein 0.0062 0.0249 0.0571
Leishmania major DNA polymerase kappa, putative 0.0118 0.0534 0.697
Trypanosoma brucei DNA polymerase IV, putative 0.0131 0.0602 0.7869
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0049 0.0182 0.0263
Leishmania major ATP-dependent DEAD/H DNA helicase recQ, putative 0.0025 0.0057 0.066
Echinococcus multilocularis ATP dependent DNA helicase Q5 0.0019 0.0029 0.0057
Echinococcus multilocularis lamin dm0 0.0027 0.0068 0.0149
Trypanosoma brucei DNA polymerase kappa, putative 0.0138 0.0636 0.8313
Trypanosoma brucei dihydrolipoamide dehydrogenase, point mutation 0.0049 0.0182 0.2312
Trichomonas vaginalis alpha-glucosidase, putative 0.0036 0.0114 0.0948
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.015 0.0698 0.9132
Schistosoma mansoni tar DNA-binding protein 0.0062 0.0249 0.0571
Echinococcus granulosus jun protein 0.0081 0.0347 0.08
Loa Loa (eye worm) hypothetical protein 0.0058 0.0229 0.1298
Plasmodium vivax hypothetical protein, conserved 0.0035 0.0108 0.1257
Trypanosoma brucei DNA polymerase IV, putative 0.0138 0.0636 0.8313
Wolbachia endosymbiont of Brugia malayi dihydrolipoamide dehydrogenase E3 component 0.0049 0.0182 0.0133
Treponema pallidum cation-transporting ATPase, P-type 0.0032 0.0093 0.006
Onchocerca volvulus 0.0027 0.0068 0.0564
Loa Loa (eye worm) hypothetical protein 0.0027 0.0068 0.0384
Plasmodium falciparum holo-[acyl-carrier-protein] synthase, putative 0.0023 0.005 0.0374
Toxoplasma gondii ImpB/MucB/SamB family protein 0.0086 0.037 0.1323
Treponema pallidum UDP-N-acetylglucosamine 1-carboxyvinyltransferase 0.1966 1 1
Brugia malayi polk-prov protein 0.0061 0.0243 0.1376
Brugia malayi cathepsin L-like cysteine proteinase, identical 0.0022 0.0043 0.0245
Brugia malayi Smad1 0.0024 0.0056 0.0316
Loa Loa (eye worm) hypothetical protein 0.0098 0.0431 0.2441
Echinococcus granulosus ATP dependent DNA helicase Q1 0.0019 0.0029 0.0057
Echinococcus multilocularis phosphoserine phosphatase 0.002 0.0033 0.0069
Loa Loa (eye worm) hypothetical protein 0.0035 0.0108 0.061
Trypanosoma brucei DNA damage repair protein, putative 0.0035 0.0108 0.1327
Loa Loa (eye worm) CYP4Cod1 0.0016 0.0011 0.0064
Echinococcus multilocularis Polycystic kidney disease protein 0.002 0.0031 0.0063
Plasmodium falciparum glutathione reductase 0.0049 0.0182 0.2391
Mycobacterium ulcerans metal cation transporter p-type ATPase, CtpV 0.0032 0.0093 0.0082
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.015 0.0698 0.9132
Brugia malayi fibroinase precursor 0.0018 0.0025 0.0142
Brugia malayi Cytochrome P450 family protein 0.0026 0.0064 0.0361
Loa Loa (eye worm) hypothetical protein 0.0051 0.0194 0.1101
Trichomonas vaginalis plasma membrane calcium-transporting ATPase, putative 0.011 0.0496 0.4326
Brugia malayi Papain family cysteine protease containing protein 0.004 0.0137 0.0779
Loa Loa (eye worm) sodium potassium adenosine triphosphatase 0.0044 0.0155 0.0878
Loa Loa (eye worm) hypothetical protein 0.0026 0.0062 0.0354
Loa Loa (eye worm) hypothetical protein 0.0034 0.0107 0.0609
Loa Loa (eye worm) hypothetical protein 0.0018 0.0025 0.0142

Activities

Activity type Activity value Assay description Source Reference
Inhibition (binding) = 18 % Inhibition of SIRT2 at 200 uM ChEMBL. 17181175
Inhibition (binding) = 18 % Inhibition of SIRT2 at 200 uM ChEMBL. 17181175

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
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External resources for this compound

No external resources registered for this compound

Bibliographic References

1 literature reference was collected for this gene.

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