Detailed information for compound 410028

Basic information

Technical information
  • Name: Unnamed compound
  • MW: 334.413 | Formula: C24H18N2
  • H donors: 0 H acceptors: 0 LogP: 5.77 Rotable bonds: 4
    Rule of 5 violations (Lipinski): 1
  • SMILES: c1ccc2c(c1)c(/N=C/c1ccccc1)ccc2/N=C/c1ccccc1
  • InChi: 1S/C24H18N2/c1-3-9-19(10-4-1)17-25-23-15-16-24(22-14-8-7-13-21(22)23)26-18-20-11-5-2-6-12-20/h1-18H/b25-17+,26-18+
  • InChiKey: VWCZXIIPPIWFIV-RPCRKUJJSA-N  


Substructure search Similarity search

Network

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Synonyms

No synonyms found for this compound

Targets

Known targets for this compound

No curated genes were found associated with this compound

Predicted pathogen targets for this compound

By orthology
No druggable targets predicted by orthology data
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Leishmania major vacuolar-type Ca2 -ATPase, putative 0.011 0.0496 0.6464
Mycobacterium ulcerans 3-phosphoshikimate 1-carboxyvinyltransferase 0.0554 0.277 0.2761
Echinococcus multilocularis cation transporting ATPase 13A1 0.0032 0.0093 0.0207
Onchocerca volvulus 0.0056 0.022 0.1906
Schistosoma mansoni DNA polymerase IV / kappa 0.0035 0.0108 0.0242
Loa Loa (eye worm) hypothetical protein 0.0026 0.0062 0.0354
Schistosoma mansoni hypothetical protein 0.0023 0.0049 0.0105
Trypanosoma brucei DNA polymerase kappa, putative 0.0138 0.0636 0.8313
Trypanosoma brucei PAB1-binding protein , putative 0.0051 0.0194 0.2473
Mycobacterium tuberculosis Probable dehydrogenase 0.0323 0.1585 0.2158
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0056 0.022 0.1881
Schistosoma mansoni calcium-transporting atpase 2 (atpase 2) 0.0127 0.058 0.134
Schistosoma mansoni chromodomain helicase DNA binding protein 0.0035 0.0108 0.0242
Plasmodium vivax unspecified product 0.0022 0.0043 0.0278
Entamoeba histolytica cysteine protease, putative 0.004 0.0137 0.1742
Echinococcus multilocularis cathepsin l cysteine peptidase 0.0056 0.022 0.0503
Echinococcus multilocularis phosphoserine phosphatase 0.002 0.0033 0.0069
Echinococcus granulosus calcium transporting ATPase type 2C member 0.0147 0.0682 0.1579
Trichomonas vaginalis PIKK family atypical protein kinase 0.0027 0.0067 0.053
Trypanosoma brucei glucosidase, putative 0.0036 0.0114 0.1416
Toxoplasma gondii haloacid dehalogenase family hydrolase domain-containing protein 0.0032 0.0093 0.0319
Toxoplasma gondii NADPH-glutathione reductase 0.0049 0.0182 0.0642
Echinococcus multilocularis phospholipid transporting ATPase VA 0.002 0.0033 0.0069
Echinococcus granulosus dna polymerase kappa 0.0138 0.0636 0.1471
Echinococcus multilocularis cation transporting atpase worm 0.0032 0.0093 0.0207
Brugia malayi E1-E2 ATPase family protein 0.0032 0.0093 0.0526
Mycobacterium ulcerans metal cation transporter p-type ATPase a 0.01 0.0444 0.0433
Entamoeba histolytica hypothetical protein 0.0035 0.0108 0.128
Echinococcus multilocularis nuclear factor of activated T cells 5 0.0073 0.0305 0.07
Echinococcus multilocularis tar DNA binding protein 0.0062 0.0249 0.0571
Trichomonas vaginalis ATPase, class I, type 8B, putative 0.0032 0.0093 0.0756
Entamoeba histolytica cysteine proteinase 2 0.004 0.0137 0.1742
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0056 0.022 0.1881
Entamoeba histolytica cysteine proteinase 1, putative 0.004 0.0137 0.1742
Onchocerca volvulus 0.0093 0.0409 0.3577
Trypanosoma brucei DNA damage repair protein, putative 0.0035 0.0108 0.1327
Brugia malayi calcium ATPase 0.0047 0.017 0.0961
Echinococcus granulosus Ca2 transporting ATPase plasma membrane 0.009 0.0394 0.0907
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0018 0.0025 0.0156
Schistosoma mansoni DNA helicase recq1 0.0019 0.0029 0.0057
Mycobacterium tuberculosis Probable reductase 0.0323 0.1585 0.2158
Echinococcus granulosus Alpha N acetylgalactosaminidase 0.0102 0.0451 0.1041
Loa Loa (eye worm) hypothetical protein 0.0019 0.0029 0.0162
Brugia malayi cathepsin L-like precursor 0.0034 0.0107 0.0609
Brugia malayi Papain family cysteine protease containing protein 0.0018 0.0025 0.0142
Echinococcus multilocularis mitogen activated protein kinase 3 0.0051 0.019 0.0432
Loa Loa (eye worm) cytoplasmic intermediate filament protein 0.0014 0.0004 0.0024
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.003 0.0086 0.019
Entamoeba histolytica hypothetical protein 0.0144 0.067 1
Brugia malayi Bloom's syndrome protein homolog 0.0046 0.0168 0.0949
Loa Loa (eye worm) hypothetical protein 0.0035 0.0108 0.061
Trichomonas vaginalis cation-transporting ATPase, putative 0.0064 0.0257 0.2213
Schistosoma mansoni smad1 5 8 and 0.0024 0.0056 0.0121
Brugia malayi Cytochrome P450 family protein 0.0016 0.0011 0.0064
Giardia lamblia Sgs1 DNA helicase, putative 0.0019 0.0029 0.007
Wolbachia endosymbiont of Brugia malayi dihydrolipoamide dehydrogenase E3 component 0.0049 0.0182 0.0133
Schistosoma mansoni chromobox protein 0.0153 0.0715 0.1655
Onchocerca volvulus 0.002 0.0031 0.0239
Loa Loa (eye worm) hypothetical protein 0.0049 0.0182 0.1031
Brugia malayi TAR-binding protein 0.0062 0.0249 0.1413
Echinococcus multilocularis Na+:K+ ATPase alpha subunit 0.008 0.0341 0.0786
Loa Loa (eye worm) hypothetical protein 0.0026 0.0062 0.0354
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0035 0.0108 0.0887
Onchocerca volvulus Peroxidasin homolog 0.0026 0.0062 0.0517
Trichomonas vaginalis r2r3-MYB transcription factor, putative 0.0048 0.0175 0.1486
Trypanosoma cruzi hypothetical protein, conserved 0.0036 0.0114 0.0161
Treponema pallidum cation-transporting ATPase, P-type 0.0032 0.0093 0.006
Echinococcus granulosus FKBP12 rapamycin complex associated protein 0.0045 0.0159 0.0361
Echinococcus granulosus plasma membrane calcium transporting ATPase 2 0.011 0.0496 0.1146
Trichomonas vaginalis r2r3-MYB transcription factor, putative 0.0048 0.0175 0.1486
Trichomonas vaginalis PIKK family atypical protein kinase 0.0035 0.0112 0.0929
Mycobacterium ulcerans dihydrolipoamide dehydrogenase 0.0049 0.0182 0.0171
Plasmodium vivax holo-[acyl-carrier-protein] synthase, putative 0.0023 0.005 0.0374
Plasmodium vivax DNA repair protein REV1, putative 0.0035 0.0108 0.1259
Brugia malayi polk-prov protein 0.0061 0.0243 0.1376
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0056 0.022 0.1881
Schistosoma mansoni cathepsin C 0.0018 0.0025 0.0049
Echinococcus multilocularis Alpha N acetylgalactosaminidase 0.0102 0.0451 0.1041
Mycobacterium tuberculosis Possible metal cation transporting P-type ATPase CtpH 0.0068 0.0279 0.0323
Trichomonas vaginalis PIKK family atypical protein kinase 0.0024 0.0054 0.0413
Onchocerca volvulus 0.0049 0.0182 0.1571
Entamoeba histolytica hypothetical protein 0.0144 0.067 1
Trichomonas vaginalis alpha-glucosidase, putative 0.0036 0.0114 0.0948
Schistosoma mansoni phosphatidylinositol 3-and 4-kinase 0.0015 0.0007 0.0008
Mycobacterium tuberculosis Probable cation transporter P-type ATPase D CtpD 0.0032 0.0093 0.0061
Mycobacterium tuberculosis Conserved hypothetical protein 0.0111 0.0501 0.0634
Echinococcus granulosus smad 0.0024 0.0056 0.0121
Schistosoma mansoni chromobox protein 0.0153 0.0715 0.1655
Giardia lamblia Plasma membrane calcium-transporting ATPase 2 0.008 0.0341 0.6214
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0056 0.022 0.1881
Toxoplasma gondii BRCA1 C Terminus (BRCT) domain-containing protein 0.0041 0.0141 0.0495
Trypanosoma cruzi calcium-transporting ATPase, putative 0.0048 0.0177 0.0255
Loa Loa (eye worm) hypothetical protein 0.0018 0.0025 0.0142
Plasmodium vivax hypothetical protein, conserved 0.0035 0.0108 0.1257
Echinococcus multilocularis cathepsin l cysteine peptidase 0.0056 0.022 0.0503
Treponema pallidum UDP-N-acetylglucosamine 1-carboxyvinyltransferase 0.1966 1 1
Schistosoma mansoni type V p-type atpase isoform 0.0032 0.0093 0.0207
Entamoeba histolytica phosphatidylinositol3-kinaseTor2, putative 0.0045 0.0159 0.2077
Brugia malayi Death domain containing protein 0.0014 0.0004 0.0022
Trypanosoma cruzi cysteine peptidase, putative 0.0056 0.022 0.032
Echinococcus multilocularis peroxidasin 0.0026 0.0062 0.0136
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.015 0.0698 0.9132
Brugia malayi cathepsin L-like cysteine proteinase 0.0018 0.0025 0.0142
Leishmania major target of rapamycin (TOR) kinase 2, putative 0.0045 0.0159 0.2006
Schistosoma mansoni ATPase 0.0147 0.0682 0.1579
Giardia lamblia Plasma membrane calcium-transporting ATPase 2 0.011 0.0496 0.925
Trypanosoma cruzi cysteine peptidase (N-terminal), putative 0.004 0.0137 0.0196
Schistosoma mansoni intermediate filament proteins 0.0027 0.0068 0.0149
Trichomonas vaginalis plasma membrane calcium-transporting ATPase, putative 0.011 0.0496 0.4326
Trichomonas vaginalis PIKK family atypical protein kinase 0.0026 0.0066 0.0518
Brugia malayi Sodium/potassium-transporting ATPase alpha-3 chain, putative 0.0044 0.0155 0.0878
Trichomonas vaginalis PIKK family atypical protein kinase 0.0027 0.0067 0.053
Entamoeba histolytica hypothetical protein 0.0035 0.0108 0.128
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.015 0.0698 0.9132
Brugia malayi aminoadipate-semialdehyde dehydrogenase-phosphopantetheinyl transferase 0.0082 0.0353 0.2
Onchocerca volvulus 0.0056 0.022 0.1906
Echinococcus multilocularis arachidonate 5 lipoxygenase 0.0055 0.0211 0.0483
Echinococcus multilocularis chromobox protein 1 0.0153 0.0715 0.1655
Echinococcus granulosus Basic leucine zipper bZIP transcription factor 0.0081 0.0347 0.08
Giardia lamblia NADH oxidase lateral transfer candidate 0.0049 0.0182 0.3085
Trypanosoma brucei trypanothione reductase 0.0142 0.0656 0.858
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0018 0.0025 0.0156
Echinococcus multilocularis calcium transporting atpase 0.0127 0.058 0.134
Schistosoma mansoni cation-transporting ATPase 0.0032 0.0093 0.0207
Trypanosoma brucei Phosphatidylinositol 3-kinase tor1 0.0045 0.0159 0.2006
Trichomonas vaginalis conserved hypothetical protein 0.0035 0.0108 0.0887
Brugia malayi latrophilin 2 splice variant baaae 0.0033 0.0102 0.0579
Onchocerca volvulus 0.0027 0.0068 0.0564
Loa Loa (eye worm) hypothetical protein 0.0035 0.0108 0.061
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0056 0.022 0.1881
Echinococcus granulosus geminin 0.0853 0.43 1
Trichomonas vaginalis MYB, putative 0.0048 0.0176 0.1497
Entamoeba histolytica cysteine proteinase, putative 0.004 0.0137 0.1742
Trypanosoma brucei vacuolar-type Ca2+-ATPase 1 0.011 0.0496 0.6464
Leishmania major calcium motive p-type ATPase, putative 0.008 0.0341 0.4419
Brugia malayi cathepsin B-like cysteine proteinase 0.0018 0.0025 0.0142
Brugia malayi SET domain containing protein 0.0036 0.0116 0.066
Leishmania major DNA polymerase kappa, putative 0.0118 0.0534 0.697
Loa Loa (eye worm) hypothetical protein 0.0082 0.0353 0.2
Loa Loa (eye worm) cysteine protease 0.0056 0.022 0.1246
Trichomonas vaginalis cation-transporting ATPase, putative 0.011 0.0496 0.4326
Plasmodium falciparum ADP-dependent DNA helicase RecQ 0.0041 0.0139 0.1732
Loa Loa (eye worm) hypothetical protein 0.0162 0.0763 0.4325
Leishmania major trypanothione reductase 0.0142 0.0656 0.858
Plasmodium falciparum DNA repair protein REV1, putative 0.0035 0.0108 0.1259
Mycobacterium ulcerans cation-transporter p-type ATPase B CtpB 0.0032 0.0093 0.0082
Schistosoma mansoni hypothetical protein 0.0015 0.001 0.0015
Onchocerca volvulus Peroxidasin homolog 0.0026 0.0062 0.0517
Echinococcus multilocularis phosphoserine phosphatase 0.002 0.0033 0.0069
Echinococcus multilocularis jun protein 0.0081 0.0347 0.08
Onchocerca volvulus 0.0124 0.0564 0.4941
Plasmodium falciparum calcium-transporting ATPase 0.0127 0.058 0.8441
Trypanosoma cruzi dihydrolipoyl dehydrogenase, putative 0.0049 0.0182 0.0263
Schistosoma mansoni calcium-transporting atpase sarcoplasmic/endoplasmic reticulum type (calcium pump) 0.0127 0.058 0.134
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0049 0.0182 0.0263
Trypanosoma brucei dihydrolipoyl dehydrogenase 0.0049 0.0182 0.2312
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0018 0.0025 0.0156
Trichomonas vaginalis DNA polymerase eta, putative 0.0138 0.0636 0.5564
Loa Loa (eye worm) hypothetical protein 0.0026 0.0062 0.0354
Echinococcus multilocularis geminin 0.0853 0.43 1
Mycobacterium tuberculosis Cation transporter P-type ATPase a CtpA 0.0032 0.0093 0.0061
Leishmania major hypothetical protein, conserved 0.0051 0.0194 0.2473
Schistosoma mansoni cation-transporting atpase worm 0.0032 0.0093 0.0207
Trichomonas vaginalis chromobox protein, putative 0.0153 0.0715 0.6265
Schistosoma mansoni chromobox protein-related (chromobox 1) (heterochromatin 1) 0.0035 0.0108 0.0242
Mycobacterium ulcerans DNA polymerase IV 0.0138 0.0636 0.0625
Leishmania major DNA polymerase kappa, putative,DNA polymerase IV, putative 0.0118 0.0534 0.697
Schistosoma mansoni hypothetical protein 0.0035 0.0108 0.0242
Echinococcus multilocularis microtubule associated protein 2 0.0684 0.3434 0.7986
Echinococcus granulosus survival motor neuron protein 1 0.0234 0.1131 0.2625
Brugia malayi ImpB/MucB/SamB family protein 0.0111 0.0501 0.2837
Echinococcus granulosus chromobox protein 1 0.0153 0.0715 0.1655
Trichomonas vaginalis PIKK family atypical protein kinase 0.0033 0.0101 0.0825
Trypanosoma cruzi cruzipain precursor, putative 0.1312 0.6651 1
Loa Loa (eye worm) hypothetical protein 0.0026 0.0062 0.0354
Leishmania major calcium-translocating P-type ATPase 0.0147 0.0682 0.8926
Onchocerca volvulus Cathepsin L homolog 0.0056 0.022 0.1906
Mycobacterium ulcerans DNA polymerase IV 0.0138 0.0636 0.0625
Echinococcus granulosus cathepsin L cysteine protease 0.004 0.0137 0.0311
Trichomonas vaginalis cation-transporting ATPase, putative 0.0147 0.0682 0.5974
Entamoeba histolytica hypothetical protein 0.0144 0.067 1
Entamoeba histolytica cysteine proteinase, putative 0.004 0.0137 0.1742
Schistosoma mansoni na+/k+ atpase alpha subunit 0.008 0.0341 0.0786
Schistosoma mansoni cpg binding protein 0.0028 0.0077 0.017
Trypanosoma brucei ATP-dependent DEAD/H DNA helicase recQ, putative 0.0025 0.0057 0.066
Schistosoma mansoni tar DNA-binding protein 0.0062 0.0249 0.0571
Giardia lamblia Phospholipid-transporting ATPase IA, putative 0.0032 0.0093 0.1331
Toxoplasma gondii chromodomain helicase DNA binding protein CHD1/SWI2/SNF2 0.0035 0.0108 0.0373
Trichomonas vaginalis alpha-galactosidase/alpha-N-acetylgalactosaminidase, putative 0.0068 0.0278 0.2393
Brugia malayi Protein cec-1. 0.0035 0.0108 0.061
Trypanosoma cruzi calcium motive p-type ATPase, putative 0.008 0.0341 0.0503
Schistosoma mansoni alpha-glucosidase 0.0139 0.0643 0.1487
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0056 0.022 0.1881
Trypanosoma brucei vacuolar-type Ca2+-ATPase, putative 0.011 0.0496 0.6464
Wolbachia endosymbiont of Brugia malayi UDP-N-acetylglucosamine 1-carboxyvinyltransferase 0.1966 1 1
Trichomonas vaginalis MYB3r3, putative 0.0048 0.0175 0.1486
Entamoeba histolytica Niemann-Pick C1 protein, putative 0.0098 0.0431 0.6287
Trichomonas vaginalis chromobox protein, putative 0.0097 0.0427 0.3713
Brugia malayi Doublecortin family protein 0.002 0.0031 0.0176
Brugia malayi Smad1 0.0024 0.0056 0.0316
Trichomonas vaginalis conserved hypothetical protein 0.0035 0.0108 0.0887
Schistosoma mansoni hypothetical protein 0.0066 0.0269 0.0618
Trichomonas vaginalis PIKK family atypical protein kinase 0.0045 0.0159 0.1343
Loa Loa (eye worm) papain family cysteine protease containing protein 0.0018 0.0025 0.0142
Mycobacterium leprae DIHYDROLIPOAMIDE DEHYDROGENASE LPD (LIPOAMIDE REDUCTASE (NADH)) (LIPOYL DEHYDROGENASE) (DIHYDROLIPOYL DEHYDROGENASE) (DIAPHORASE 0.0359 0.1769 0.2418
Trypanosoma brucei dihydrolipoamide dehydrogenase 0.0049 0.0182 0.2312
Plasmodium falciparum dihydrolipoyl dehydrogenase, apicoplast 0.0049 0.0182 0.2391
Onchocerca volvulus 0.0124 0.0564 0.4941
Trichomonas vaginalis conserved hypothetical protein 0.0038 0.0125 0.1044
Trichomonas vaginalis C-MYB, putative 0.0048 0.0175 0.1486
Echinococcus multilocularis tumor protein p63 0.0335 0.1646 0.3824
Trichomonas vaginalis CMGC family protein kinase 0.0051 0.019 0.1613
Brugia malayi cathepsin F-like cysteine proteinase 0.0018 0.0025 0.0142
Schistosoma mansoni atpase class VI type 11c 0.002 0.0033 0.0069
Brugia malayi cathepsin F-like cysteine proteinase 0.0022 0.0043 0.0245
Echinococcus multilocularis TGF beta signal transducer SmadC 0.0024 0.0056 0.0121
Plasmodium falciparum ataxin-2 like protein, putative 0.0051 0.0194 0.2577
Echinococcus granulosus thioredoxin glutathione reductase 0.0142 0.0656 0.1518
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.004 0.0137 0.172
Echinococcus granulosus chromobox protein 1 0.0153 0.0715 0.1655
Trichomonas vaginalis conserved hypothetical protein 0.0056 0.0219 0.1874
Loa Loa (eye worm) CHromoDomain protein family member 0.0036 0.0116 0.0657
Schistosoma mansoni tar DNA-binding protein 0.0062 0.0249 0.0571
Loa Loa (eye worm) hypothetical protein 0.0036 0.0117 0.0665
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0018 0.0025 0.0156
Echinococcus granulosus TGF beta signal transducer SmadC 0.0024 0.0056 0.0121
Schistosoma mansoni serine/threonine protein kinase 0.0051 0.019 0.0432
Trichomonas vaginalis Clan CA, family C1, cathepsin B-like cysteine peptidase 0.0018 0.0025 0.0156
Entamoeba histolytica hypothetical protein 0.0144 0.067 1
Echinococcus granulosus diuretic hormone 44 receptor GPRdih2 0.0015 0.001 0.0015
Onchocerca volvulus 0.0026 0.0062 0.0517
Onchocerca volvulus 0.002 0.0031 0.0239
Echinococcus granulosus cathepsin L 0.004 0.0137 0.0311
Loa Loa (eye worm) hypothetical protein 0.0032 0.0093 0.0526
Echinococcus multilocularis histone lysine N methyltransferase SETMAR 0.003 0.0086 0.019
Echinococcus multilocularis bloom syndrome protein 0.0046 0.0168 0.0381
Entamoeba histolytica Plasma membrane calcium-transporting ATPase, putative 0.011 0.0496 0.7298
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0056 0.022 0.1881
Leishmania major proton motive ATPase, putative 0.0032 0.0093 0.113
Loa Loa (eye worm) hypothetical protein 0.0042 0.0145 0.0824
Schistosoma mansoni hypothetical protein 0.0048 0.0176 0.04
Trichomonas vaginalis r2r3-MYB transcription factor, putative 0.0048 0.0175 0.1486
Loa Loa (eye worm) hypothetical protein 0.0121 0.0553 0.3133
Schistosoma mansoni SmCL2-like peptidase (C01 family) 0.004 0.0137 0.0311
Schistosoma mansoni hypothetical protein 0.004 0.0138 0.0311
Echinococcus granulosus RUN 0.002 0.0031 0.0063
Echinococcus granulosus Ankyrin repeat domain containing protein 0.0089 0.0387 0.0892
Loa Loa (eye worm) hypothetical protein 0.0015 0.001 0.0058
Trypanosoma cruzi plasma membrane Ca2+ ATPase 0.011 0.0496 0.0735
Echinococcus granulosus jun protein 0.0081 0.0347 0.08
Trichomonas vaginalis set domain proteins, putative 0.0235 0.1137 1
Brugia malayi Cathepsin L-like precursor 0.0056 0.022 0.1246
Echinococcus multilocularis thioredoxin glutathione reductase 0.0142 0.0656 0.1518
Plasmodium vivax unspecified product 0.004 0.0137 0.1711
Entamoeba histolytica cysteine proteinase, putative 0.004 0.0137 0.1742
Mycobacterium leprae probable 3-phosphoshikimate 1-carboxyvinyl transferase AroA (5-ENOLPYRUVYLSHIKIMATE-3-PHOSPHATE SYNTHASE) (EPSP SYNTHASE) (EPSPS 0.0554 0.277 0.3824
Plasmodium vivax ataxin-2 like protein, putative 0.0051 0.0194 0.2577
Plasmodium falciparum ATP-dependent DNA helicase Q1 0.0019 0.0029 0.0054
Brugia malayi Cytochrome P450 family protein 0.0016 0.0011 0.0064
Trypanosoma cruzi calcium-translocating P-type ATPase, putative 0.0083 0.0356 0.0524
Trichomonas vaginalis PIKK family atypical protein kinase 0.0024 0.0054 0.0412
Brugia malayi ATP-dependent DNA helicase, RecQ family protein 0.0019 0.0029 0.0162
Schistosoma mansoni retinoblastoma-binding protein 4 (rbbp4) 0.0014 0.0005 0.0001
Brugia malayi cytoplasmic intermediate filament protein 0.0014 0.0004 0.0024
Echinococcus multilocularis chromobox protein 1 0.0153 0.0715 0.1655
Brugia malayi CHD4 protein 0.0036 0.0116 0.0657
Echinococcus granulosus cathepsin l1 0.0056 0.022 0.0503
Echinococcus granulosus L aminoadipate semialdehyde 0.0082 0.0353 0.0813
Brugia malayi Calcitonin receptor-like protein seb-1 0.0049 0.0181 0.1028
Trypanosoma brucei P-type H+-ATPase, putative 0.0064 0.0257 0.3306
Schistosoma mansoni SmCL2-like peptidase (C01 family) 0.004 0.0137 0.0311
Echinococcus multilocularis cpg binding protein 0.003 0.0085 0.0189
Trichomonas vaginalis PIKK family atypical protein kinase 0.0024 0.0054 0.0413
Trichomonas vaginalis Clan CA, family C1, cathepsin B-like cysteine peptidase 0.0018 0.0025 0.0156
Trypanosoma brucei DNA polymerase kappa, putative 0.0138 0.0636 0.8313
Loa Loa (eye worm) immunoglobulin I-set domain-containing protein 0.0014 0.0004 0.0022
Brugia malayi Cytochrome P450 family protein 0.0026 0.0064 0.0361
Schistosoma mansoni subfamily C1A unassigned peptidase (C01 family) 0.0018 0.0025 0.0049
Trichomonas vaginalis PIKK family atypical protein kinase 0.0035 0.0112 0.0929
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.015 0.0698 0.9132
Trichomonas vaginalis ATPase, class VI, type 11C, putative 0.0032 0.0093 0.0756
Toxoplasma gondii plasma membrane-type Ca(2+)-ATPase A1 PMCAA1 0.009 0.0394 0.1407
Echinococcus granulosus lysosomal alpha glucosidase 0.0161 0.0758 0.1756
Trichomonas vaginalis PIKK family atypical protein kinase 0.0033 0.0101 0.0825
Schistosoma mansoni hypothetical protein 0.0286 0.1394 0.3235
Echinococcus granulosus plasma membrane calcium transporting ATPase 0.009 0.0394 0.0907
Loa Loa (eye worm) papain family cysteine protease containing protein 0.0056 0.022 0.1246
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.015 0.0698 0.9132
Mycobacterium leprae PROBABLE CATION-TRANSPORTER ATPASE I CTPI 0.0068 0.0279 0.0323
Plasmodium vivax vivapain-1 0.004 0.0137 0.1711
Loa Loa (eye worm) hypothetical protein 0.01 0.0444 0.2515
Echinococcus multilocularis Chromobox protein 3 0.0035 0.0108 0.0242
Trichomonas vaginalis plasma membrane calcium-transporting ATPase, putative 0.011 0.0496 0.4326
Schistosoma mansoni hypothetical protein 0.004 0.0138 0.0311
Leishmania major P-type H -ATPase, putative 0.0064 0.0257 0.3306
Loa Loa (eye worm) hypothetical protein 0.002 0.0031 0.0176
Leishmania major cathepsin L-like protease 0.0056 0.022 0.2811
Schistosoma mansoni jun-related protein 0.0066 0.0269 0.0618
Echinococcus multilocularis mothers against decapentaplegic 5 0.0024 0.0056 0.0121
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0018 0.0025 0.0156
Trichomonas vaginalis Clan CA, family C1, cathepsin F-like cysteine peptidase 0.0018 0.0025 0.0156
Trypanosoma cruzi calcium-translocating P-type ATPase, putative 0.0044 0.0155 0.0222
Brugia malayi Membrane calcium atpase protein 3 0.009 0.0394 0.223
Chlamydia trachomatis dihydrolipoyl dehydrogenase 0.0049 0.0182 0.0133
Schistosoma mansoni dihydrolipoamide dehydrogenase 0.0049 0.0182 0.0415
Trypanosoma brucei DNA polymerase kappa, putative 0.0138 0.0636 0.8313
Loa Loa (eye worm) ImpB/MucB/SamB family protein 0.0111 0.0501 0.2837
Onchocerca volvulus 0.0018 0.0025 0.0186
Brugia malayi CXXC zinc finger family protein 0.0028 0.0077 0.0435
Brugia malayi ImpB/MucB/SamB family protein 0.0162 0.0763 0.4325
Echinococcus granulosus Smad4 0.0024 0.0056 0.0121
Trypanosoma cruzi trypanothione reductase, putative 0.0142 0.0656 0.0976
Toxoplasma gondii cathepsin CPC2 0.0018 0.0025 0.0074
Onchocerca volvulus 0.0028 0.0077 0.0642
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0018 0.0025 0.0156
Trichomonas vaginalis r2r3-MYB transcription factor, putative 0.0048 0.0175 0.1486
Schistosoma mansoni aminoadipate-semialdehyde dehydrogenase 0.0082 0.0353 0.0813
Trichomonas vaginalis PIKK family atypical protein kinase 0.0045 0.0159 0.1343
Toxoplasma gondii 'chromo' (CHRromatin Organization MOdifier) domain-containing protein 0.0035 0.0108 0.0373
Trypanosoma brucei target of rapamycin kinase 3, putative 0.0035 0.0113 0.1391
Trichomonas vaginalis chromobox protein, putative 0.0035 0.0108 0.0887
Giardia lamblia Potassium-transporting ATPase alpha chain 1 0.008 0.0341 0.6214
Leishmania major cysteine peptidase C (CPC),CPC cysteine peptidase, Clan CA, family C1, Cathepsin B-like 0.0018 0.0025 0.0233
Loa Loa (eye worm) papain family cysteine protease containing protein 0.0022 0.0043 0.0245
Echinococcus granulosus sarco:endoplasmic reticulum calcium ATPase 0.0147 0.0682 0.1579
Schistosoma mansoni subfamily C1A unassigned peptidase (C01 family) 0.0018 0.0025 0.0049
Brugia malayi Pre-SET motif family protein 0.0207 0.0991 0.5614
Echinococcus granulosus bloom syndrome protein 0.0046 0.0168 0.0381
Loa Loa (eye worm) hypothetical protein 0.0061 0.0243 0.1376
Echinococcus multilocularis plasma membrane calcium transporting ATPase 0.009 0.0394 0.0907
Brugia malayi Calcium-transporting ATPase sarcoplasmic/endoplasmic reticulum type 0.0127 0.058 0.3284
Echinococcus granulosus mitogen activated protein kinase 0.0051 0.019 0.0432
Loa Loa (eye worm) hypothetical protein 0.0026 0.0062 0.0354
Giardia lamblia DINP protein human, muc B family 0.0118 0.0534 1
Entamoeba histolytica cysteine protease, putative 0.004 0.0137 0.1742
Trypanosoma cruzi major cysteine proteinase, putative 0.0112 0.0503 0.0746
Loa Loa (eye worm) transcription factor SMAD2 0.0358 0.1765 1
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.0018 0.0025 0.0049
Echinococcus granulosus cation transporting atpase worm 0.0032 0.0093 0.0207
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0041 0.0141 0.118
Leishmania major DNA polymerase kappa, putative 0.0035 0.0108 0.1327
Brugia malayi Valyl-tRNA synthetase 0.0035 0.0108 0.061
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0041 0.0141 0.118
Schistosoma mansoni rab6-interacting 0.002 0.0031 0.0063
Trichomonas vaginalis DNA polymerase IV / kappa, putative 0.0138 0.0636 0.5564
Loa Loa (eye worm) calcium ATPase 0.0067 0.0272 0.1541
Trypanosoma cruzi P-type H+-ATPase, putative 0.0044 0.0155 0.0222
Trypanosoma cruzi plasma-membrane proton-efflux P-type ATPase, putative 0.0044 0.0155 0.0222
Trichomonas vaginalis r2r3-MYB transcription factor, putative 0.0048 0.0175 0.1486
Echinococcus granulosus phospholipid transporting ATPase IIB 0.0032 0.0093 0.0207
Onchocerca volvulus 0.0236 0.1137 1
Brugia malayi Animal haem peroxidase family protein 0.0026 0.0062 0.0354
Echinococcus multilocularis sarco:endoplasmic reticulum calcium ATPase 0.0147 0.0682 0.1579
Plasmodium falciparum glutathione reductase 0.0142 0.0656 0.9602
Trypanosoma cruzi copper-transporting ATPase-like protein, putative 0.0032 0.0093 0.0128
Schistosoma mansoni SmCB2 peptidase (C01 family) 0.0018 0.0025 0.0049
Entamoeba histolytica phospholipid-transporting P-type ATPase, putative 0.0032 0.0093 0.105
Schistosoma mansoni alpha-galactosidase/alpha-n-acetylgalactosaminidase 0.0068 0.0278 0.0637
Loa Loa (eye worm) doublecortin family protein 0.002 0.0031 0.0176
Trypanosoma cruzi DNA damage repair protein, putative 0.0035 0.0108 0.0151
Plasmodium vivax calcium-transporting ATPase, putative 0.0147 0.0682 1
Brugia malayi RNA recognition motif domain containing protein 0.0062 0.0249 0.1413
Mycobacterium ulcerans metal cation-transporting p-type ATPase CtpC 0.0032 0.0093 0.0082
Loa Loa (eye worm) MH2 domain-containing protein 0.0024 0.0056 0.0316
Schistosoma mansoni cathepsin F (C01 family) 0.0056 0.022 0.0503
Entamoeba histolytica calcium-transporting P-type ATPase, putative 0.01 0.0444 0.649
Plasmodium falciparum cysteine proteinase falcipain 2b 0.0056 0.022 0.2966
Entamoeba histolytica plasma membrane calcium-transporting ATPase 1, putative 0.0067 0.0272 0.3827
Echinococcus granulosus histone lysine methyltransferase setb 0.003 0.0086 0.019
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.004 0.0137 0.172
Trypanosoma cruzi cysteine peptidase, putative 0.004 0.0137 0.0196
Loa Loa (eye worm) thioredoxin reductase 0.0142 0.0656 0.3717
Loa Loa (eye worm) hypothetical protein 0.0014 0.0004 0.0022
Echinococcus granulosus cathepsin l cysteine peptidase 0.0056 0.022 0.0503
Wolbachia endosymbiont of Brugia malayi dihydrolipoamide dehydrogenase E3 component 0.0049 0.0182 0.0133
Echinococcus granulosus dnaJ subfamily B 0.0405 0.2007 0.4664
Onchocerca volvulus Heterochromatin protein 1 homolog 0.0091 0.0396 0.3458
Leishmania major DNA polymerase eta, putative 0.0086 0.037 0.4801
Trypanosoma cruzi DNA polymerase kappa, putative 0.0138 0.0636 0.0946
Entamoeba histolytica Plasma membrane calcium-transporting ATPase, putative 0.011 0.0496 0.7298
Leishmania major calcium-transporting ATPase, putative 0.008 0.0341 0.4419
Trypanosoma cruzi mitogen-activated protein kinase 11, putative 0.0051 0.019 0.0274
Brugia malayi cahepsin L-like non-peptiedase homolog 0.0018 0.0025 0.0142
Leishmania major alpha glucosidase II subunit, putative 0.0036 0.0114 0.1416
Echinococcus granulosus microtubule associated protein 2 0.0684 0.3434 0.7986
Trypanosoma brucei P-type H+-ATPase, putative 0.0064 0.0257 0.3306
Trypanosoma cruzi hypothetical protein, conserved 0.0036 0.0114 0.0161
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.0018 0.0025 0.0049
Mycobacterium tuberculosis Putative ferredoxin reductase 0.0323 0.1585 0.2158
Brugia malayi Pre-SET motif family protein 0.003 0.0086 0.0485
Trichomonas vaginalis Clan CA, family C1, cathepsin B-like cysteine peptidase 0.0018 0.0025 0.0156
Echinococcus granulosus Ataxin 2 N terminaldomain containing protein 0.0023 0.0049 0.0105
Brugia malayi Immunoglobulin I-set domain containing protein 0.0014 0.0004 0.0022
Echinococcus multilocularis phosphoserine phosphatase 0.002 0.0033 0.0069
Trypanosoma brucei DNA polymerase kappa, putative 0.0138 0.0636 0.8313
Onchocerca volvulus 0.0048 0.0176 0.1517
Trichomonas vaginalis maltase-glucoamylase, putative 0.0036 0.0114 0.0948
Loa Loa (eye worm) phosphatidylinositol 3 0.0015 0.0007 0.0042
Echinococcus multilocularis copper transporting ATPase 1 0.0032 0.0093 0.0207
Echinococcus multilocularis GPCR, family 2 0.0015 0.001 0.0015
Plasmodium vivax multidomain scavenger receptor, putative 0.002 0.0031 0.0091
Trichomonas vaginalis conserved hypothetical protein 0.0035 0.0108 0.0887
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0018 0.0025 0.0156
Brugia malayi Cathepsin L-like precursor 0.0034 0.0107 0.0609
Schistosoma mansoni cathepsin F (C01 family) 0.0056 0.022 0.0503
Leishmania major target of rapamycin (TOR) kinase 1, putative 0.0045 0.0159 0.2006
Onchocerca volvulus 0.0065 0.0262 0.2281
Mycobacterium tuberculosis Probable metal cation transporter ATPase P-type CtpE 0.0032 0.0093 0.0061
Entamoeba histolytica cysteine protease, putative 0.004 0.0137 0.1742
Echinococcus granulosus expressed conserved protein 0.0092 0.04 0.0923
Plasmodium falciparum cysteine proteinase falcipain 2a 0.0056 0.022 0.2966
Echinococcus multilocularis protein patched 0.0042 0.0145 0.0329
Echinococcus multilocularis cysteine protease 0.0056 0.022 0.0503
Trichomonas vaginalis alpha-glucosidase, putative 0.0036 0.0114 0.0948
Echinococcus granulosus cpg binding protein 0.003 0.0085 0.0189
Brugia malayi Animal haem peroxidase family protein 0.0026 0.0062 0.0354
Echinococcus multilocularis mitogen activated protein kinase 0.0051 0.019 0.0432
Trypanosoma cruzi cation-transporting ATPase, putative 0.0032 0.0093 0.0128
Entamoeba histolytica myb-like DNA-binding domain containing protein 0.0048 0.0175 0.2328
Echinococcus multilocularis cathepsin L cysteine protease 0.0056 0.022 0.0503
Leishmania major DNA polymerase eta, putative 0.0162 0.0763 1
Schistosoma mansoni smad 0.0024 0.0056 0.0121
Leishmania major cysteine peptidase A (CPA) 0.0056 0.022 0.2811
Brugia malayi cathepsin L-like cysteine proteinase, identical 0.0022 0.0043 0.0245
Trypanosoma cruzi Calcium ATPase SERCA-like 0.0147 0.0682 0.1015
Mycobacterium ulcerans 4'-phosphopantetheinyl transferase 0.0023 0.005 0.0038
Toxoplasma gondii ATP-dependent DNA helicase, RecQ family protein 0.0019 0.0029 0.0087
Echinococcus multilocularis Glycoside hydrolase, family 27 0.0102 0.0451 0.1041
Trichomonas vaginalis chromobox protein, putative 0.0097 0.0427 0.3713
Loa Loa (eye worm) hypothetical protein 0.0018 0.0025 0.0142
Trypanosoma brucei cysteine peptidase C (CPC) 0.0018 0.0025 0.0233
Schistosoma mansoni multiple ankyrin repeats single kh domain protein 0.0089 0.0387 0.0892
Onchocerca volvulus 0.0026 0.0062 0.0517
Trichomonas vaginalis PIKK family atypical protein kinase 0.0038 0.0126 0.1047
Brugia malayi E1-E2 ATPase family protein 0.0064 0.0257 0.1458
Trypanosoma cruzi DNA polymerase kappa, putative 0.0138 0.0636 0.0946
Loa Loa (eye worm) TAR-binding protein 0.0062 0.0249 0.1413
Trypanosoma cruzi cysteine peptidase, putative 0.015 0.0698 0.1039
Brugia malayi Cathepsin L-like cysteine proteinase 0.0034 0.0107 0.0609
Plasmodium falciparum glutathione reductase 0.0049 0.0182 0.2391
Trichomonas vaginalis chromobox protein, putative 0.0035 0.0108 0.0887
Trypanosoma brucei DNA polymerase IV, putative 0.0138 0.0636 0.8313
Schistosoma mansoni hypothetical protein 0.0033 0.0102 0.0229
Onchocerca volvulus 0.01 0.0444 0.3882
Loa Loa (eye worm) hypothetical protein 0.0147 0.0682 0.3865
Echinococcus granulosus tumor protein p63 0.0335 0.1646 0.3824
Mycobacterium tuberculosis NADPH-dependent mycothiol reductase Mtr 0.0142 0.0656 0.0852
Trypanosoma brucei DNA polymerase kappa, putative 0.0083 0.0357 0.463
Trypanosoma brucei DNA polymerase kappa, putative 0.0083 0.0357 0.463
Entamoeba histolytica FKBP-rapamycin associated protein (FRAP), putative 0.0045 0.0159 0.2077
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0038 0.0125 0.1044
Brugia malayi glutathione reductase 0.0142 0.0656 0.3717
Trichomonas vaginalis PIKK family atypical protein kinase 0.0035 0.0112 0.0929
Loa Loa (eye worm) animal heme peroxidase 0.0026 0.0062 0.0354
Mycobacterium tuberculosis Dihydrolipoamide dehydrogenase LpdC (lipoamide reductase (NADH)) (lipoyl dehydrogenase) (dihydrolipoyl dehydrogenase) (diaphoras 0.0359 0.1769 0.2418
Treponema pallidum 4'-phosphopantetheinyl transferase 0.0023 0.005 0.0016
Schistosoma mansoni tar DNA-binding protein 0.0062 0.0249 0.0571
Brugia malayi Peroxidasin 0.0026 0.0062 0.0354
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0018 0.0025 0.0156
Loa Loa (eye worm) hypothetical protein 0.0054 0.0207 0.1173
Brugia malayi MAP kinase sur-1 0.0051 0.019 0.1074
Brugia malayi Thioredoxin reductase 0.0142 0.0656 0.3717
Brugia malayi Cathepsin L-like precursor 0.0056 0.022 0.1246
Echinococcus multilocularis lysosomal alpha glucosidase 0.0161 0.0758 0.1756
Loa Loa (eye worm) hypothetical protein 0.0124 0.0565 0.3199
Schistosoma mansoni chromobox protein 0.0035 0.0108 0.0242
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0056 0.022 0.1881
Toxoplasma gondii preprocathepsin c precursor, putative 0.0018 0.0025 0.0074
Echinococcus multilocularis cysteine protease 0.0056 0.022 0.0503
Loa Loa (eye worm) hypothetical protein 0.0035 0.0108 0.061
Loa Loa (eye worm) CYP4Cod1 0.0016 0.0011 0.0064
Brugia malayi Animal haem peroxidase family protein 0.0026 0.0062 0.0354
Schistosoma mansoni alpha-galactosidase/alpha-n-acetylgalactosaminidase 0.0102 0.0451 0.1041
Trichomonas vaginalis conserved hypothetical protein 0.0042 0.0145 0.1222
Schistosoma mansoni rab geranylgeranyl transferase alpha subunit 0.0111 0.0501 0.1156
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0056 0.022 0.1881
Echinococcus granulosus lipoxygenase domain containing protein 0.002 0.0031 0.0063
Schistosoma mansoni patched 1 0.0042 0.0145 0.0329
Mycobacterium ulcerans cation-transporter ATPase I CtpI 0.0068 0.0279 0.0268
Echinococcus multilocularis ATP dependent DNA helicase Q5 0.0019 0.0029 0.0057
Brugia malayi MH2 domain containing protein 0.0024 0.0056 0.0316
Trichomonas vaginalis PIKK family atypical protein kinase 0.0035 0.0112 0.0929
Schistosoma mansoni alpha-galactosidase/alpha-n-acetylgalactosaminidase 0.0102 0.0451 0.1041
Onchocerca volvulus Cathepsin L homolog 0.0056 0.022 0.1906
Echinococcus multilocularis lipoxygenase domain containing protein 0.002 0.0031 0.0063
Loa Loa (eye worm) animal heme peroxidase 0.0026 0.0062 0.0354
Plasmodium falciparum cysteine proteinase falcipain 1 0.004 0.0137 0.1711
Trypanosoma cruzi mitogen activated protein kinase 4, putative 0.0051 0.019 0.0274
Schistosoma mansoni lipoxygenase 0.002 0.0031 0.0063
Plasmodium vivax heterochromatin protein 1, putative 0.0035 0.0108 0.1257
Schistosoma mansoni plasma membrane calcium-transporting atpase 0.009 0.0394 0.0907
Trichomonas vaginalis DNA helicase recq1, putative 0.0046 0.0168 0.1418
Toxoplasma gondii thioredoxin reductase 0.0142 0.0656 0.2356
Leishmania major target of rapamycin kinase (TOR) kinase 3 0.0035 0.0113 0.1391
Echinococcus granulosus chromobox protein 2 0.0035 0.0108 0.0242
Schistosoma mansoni dipeptidyl-peptidase I (C01 family) 0.0018 0.0025 0.0049
Echinococcus granulosus neuropeptide receptor A26 0.0465 0.2311 0.537
Schistosoma mansoni blooms syndrome DNA helicase 0.0036 0.0118 0.0265
Schistosoma mansoni hypothetical protein 0.004 0.0138 0.0311
Trichomonas vaginalis PIKK family atypical protein kinase 0.0024 0.0054 0.0413
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0056 0.022 0.1881
Onchocerca volvulus 0.0034 0.0107 0.0914
Echinococcus multilocularis L aminoadipate semialdehyde 0.0082 0.0353 0.0813
Trypanosoma cruzi PAB1-binding protein , putative 0.0051 0.0194 0.0281
Leishmania major dihydrolipoamide dehydrogenase, putative 0.0049 0.0182 0.2312
Trichomonas vaginalis phospholipid-transporting ATPase, putative 0.0032 0.0093 0.0756
Entamoeba histolytica cysteine proteinase, putative 0.0034 0.0107 0.1277
Trypanosoma cruzi cysteine peptidase C (CPC), putative 0.0018 0.0025 0.0027
Echinococcus granulosus neuropeptide s receptor 0.0465 0.2311 0.537
Onchocerca volvulus Peroxidase homolog 0.0026 0.0062 0.0517
Toxoplasma gondii pyruvate dehydrogenase complex subunit PDH-E3II 0.0049 0.0182 0.0642
Schistosoma mansoni alpha-galactosidase/alpha-n-acetylgalactosaminidase 0.0068 0.0278 0.0637
Trypanosoma cruzi mitogen-activated protein kinase 11, putative 0.0051 0.019 0.0274
Loa Loa (eye worm) hypothetical protein 0.0018 0.0025 0.0142
Schistosoma mansoni cation-transporting atpase worm 0.0032 0.0093 0.0207
Trypanosoma brucei mitogen activated protein kinase 4, putative 0.0051 0.019 0.241
Entamoeba histolytica chromodomain-helicase-DNA-binding protein, putative 0.0035 0.0108 0.128
Trypanosoma brucei unspecified product 0.0077 0.0324 0.4187
Loa Loa (eye worm) pigment dispersing factor receptor c 0.0049 0.0181 0.1028
Plasmodium falciparum heterochromatin protein 1 0.0035 0.0108 0.1257
Mycobacterium ulcerans metal cation transporter p-type ATPase, CtpV 0.0032 0.0093 0.0082
Brugia malayi Glycosyl hydrolases family 31 protein 0.0161 0.0758 0.4296
Echinococcus multilocularis dihydrolipoamide dehydrogenase 0.0049 0.0182 0.0415
Entamoeba histolytica glycosyl hydrolase, family 31 protein 0.0036 0.0114 0.1386
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0061 0.0246 0.0563
Trypanosoma brucei chrX additional, unordered contigs 0.0035 0.0108 0.1327
Plasmodium falciparum cysteine proteinase falcipain 3 0.0056 0.022 0.2966
Loa Loa (eye worm) hypothetical protein 0.0234 0.1131 0.6412
Leishmania major DNA damage repair protein, putative 0.0035 0.0108 0.1327
Echinococcus granulosus 5'partial|histone lysine N methyltransferase SETDB2 0.0028 0.0077 0.017
Toxoplasma gondii histone lysine methyltransferase SET/SUV39 0.003 0.0086 0.0293
Loa Loa (eye worm) phosphatidylinositol 3 0.0045 0.0159 0.0901
Brugia malayi Probable calcium-transporting ATPase KIAA0703 0.0095 0.0415 0.2352
Schistosoma mansoni cathepsin B (C01 family) 0.0018 0.0025 0.0049
Entamoeba histolytica hypothetical protein 0.0035 0.0108 0.128
Loa Loa (eye worm) hypothetical protein 0.0056 0.022 0.1246
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.0018 0.0025 0.0049
Schistosoma mansoni DNA polymerase eta 0.0162 0.0763 0.1768
Schistosoma mansoni hypothetical protein 0.0853 0.43 1
Brugia malayi Papain family cysteine protease containing protein 0.0018 0.0025 0.0142
Echinococcus multilocularis neutral alpha glucosidase AB 0.0036 0.0114 0.0257
Loa Loa (eye worm) CMGC/MAPK/ERK1 protein kinase 0.0051 0.019 0.1074
Leishmania major dihydrolipoamide dehydrogenase, putative 0.0049 0.0182 0.2312
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0056 0.022 0.1881
Entamoeba histolytica myb-like DNA-binding domain containing protein 0.0048 0.0175 0.2328
Trypanosoma brucei dihydrolipoamide dehydrogenase 0.0049 0.0182 0.2312
Echinococcus multilocularis neuropeptide s receptor 0.0465 0.2311 0.537
Loa Loa (eye worm) E1-E2 ATPase 0.0064 0.0257 0.1458
Entamoeba histolytica plasma membrane calcium-transporting ATPase, putative 0.0022 0.0043 0.0271
Trypanosoma brucei DNA polymerase kappa, putative 0.0138 0.0636 0.8313
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.003 0.0086 0.019
Trypanosoma cruzi cysteine protease, putative 0.004 0.0137 0.0196
Loa Loa (eye worm) hypothetical protein 0.0033 0.0102 0.0579
Entamoeba histolytica glycosyl hydrolase, family 31 protein 0.0036 0.0114 0.1386
Echinococcus multilocularis cathepsin L 0.004 0.0137 0.0311
Trypanosoma brucei calcium-translocating P-type ATPase 0.0127 0.058 0.757
Schistosoma mansoni ataxia telangiectasia mutated (atm)-related 0.0045 0.0159 0.0361
Trichomonas vaginalis glutathione reductase, putative 0.0049 0.0182 0.1547
Entamoeba histolytica cysteine protease, putative 0.004 0.0137 0.1742
Trichomonas vaginalis PIKK family atypical protein kinase 0.0027 0.0067 0.053
Schistosoma mansoni chromobox protein 0.0035 0.0108 0.0242
Loa Loa (eye worm) hypothetical protein 0.0091 0.0396 0.2243
Echinococcus granulosus cation transporting ATPase 13A1 0.0032 0.0093 0.0207
Trypanosoma brucei DNA polymerase IV, putative 0.0131 0.0602 0.7869
Loa Loa (eye worm) hypothetical protein 0.0051 0.0194 0.1101
Echinococcus granulosus calcium transporting atpase 0.0127 0.058 0.134
Toxoplasma gondii ImpB/MucB/SamB family protein 0.0035 0.0108 0.0373
Trichomonas vaginalis CMGC family protein kinase 0.0051 0.019 0.1613
Brugia malayi haloacid dehalogenase-like hydrolase family protein 0.0056 0.022 0.1246
Echinococcus multilocularis diuretic hormone 44 receptor GPRdih2 0.0015 0.001 0.0015
Mycobacterium tuberculosis Probable NADH dehydrogenase Ndh 0.0323 0.1585 0.2158
Schistosoma mansoni ATPase 0.0147 0.0682 0.1579
Brugia malayi hypothetical protein 0.0064 0.0258 0.1462
Leishmania major acetoin dehydrogenase e3 component-like protein 0.0049 0.0182 0.2312
Trichomonas vaginalis conserved hypothetical protein 0.0035 0.0108 0.0887
Brugia malayi chromobox protein homolog 3 0.0091 0.0396 0.2243
Echinococcus multilocularis sterol regulatory element binding protein 0.0042 0.0145 0.0329
Treponema pallidum NADH oxidase 0.0049 0.0182 0.0149
Brugia malayi Papain family cysteine protease containing protein 0.004 0.0137 0.0779
Brugia malayi MH2 domain containing protein 0.0358 0.1765 1
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0056 0.022 0.1881
Brugia malayi calcium-independent alpha-latrotoxin receptor 2, putative 0.0015 0.001 0.0058
Loa Loa (eye worm) hypothetical protein 0.0026 0.0062 0.0354
Echinococcus multilocularis chromodomain helicase DNA binding protein 4 0.0036 0.0116 0.0261
Schistosoma mansoni hypothetical protein 0.0051 0.0193 0.0441
Onchocerca volvulus 0.0082 0.0353 0.308
Brugia malayi Associated with TFs and helicases family protein 0.0035 0.0108 0.061
Loa Loa (eye worm) hypothetical protein 0.0018 0.0025 0.0142
Echinococcus granulosus cysteine protease 0.004 0.0137 0.0311
Schistosoma mansoni rab6-interacting 0.002 0.0031 0.0063
Schistosoma mansoni microtubule-associated protein tau 0.0684 0.3434 0.7986
Trichomonas vaginalis pc-MYB2, putative 0.0048 0.0175 0.1486
Loa Loa (eye worm) RNA binding protein 0.0062 0.0249 0.1413
Mycobacterium ulcerans phosphopantetheinyl transferase, PptII 0.0023 0.005 0.0038
Entamoeba histolytica cysteine protease, putative 0.004 0.0137 0.1742
Trichomonas vaginalis PIKK family atypical protein kinase 0.0024 0.0054 0.0412
Trypanosoma cruzi Phosphatidylinositol 3-kinase tor1 0.0045 0.0159 0.0228
Brugia malayi Animal haem peroxidase family protein 0.0026 0.0062 0.0354
Toxoplasma gondii shikimate dehydrogenase substrate binding domain-containing protein 0.0554 0.277 1
Loa Loa (eye worm) hypothetical protein 0.0026 0.0062 0.0354
Schistosoma mansoni cathepsin s 0.0022 0.0043 0.0092
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0041 0.0141 0.118
Brugia malayi Heterochromatin protein 1 0.0153 0.0715 0.4051
Echinococcus granulosus cathepsin b 0.0018 0.0025 0.0049
Echinococcus multilocularis Niemann Pick C1 protein 0.0098 0.0431 0.0994
Brugia malayi Animal haem peroxidase family protein 0.0026 0.0062 0.0354
Loa Loa (eye worm) hypothetical protein 0.0026 0.0062 0.0354
Brugia malayi Papain family cysteine protease containing protein 0.004 0.0137 0.0779
Brugia malayi hypothetical protein 0.002 0.0033 0.0189
Schistosoma mansoni alpha glucosidase 0.0036 0.0114 0.0257
Leishmania major P-type H -ATPase, putative 0.0064 0.0257 0.3306
Entamoeba histolytica chromodomain-helicase-DNA-binding protein, putative 0.0035 0.0108 0.128
Toxoplasma gondii phospholipid-translocating P-type ATPase, flippase subfamily protein 0.002 0.0033 0.0104
Plasmodium falciparum chromodomain-helicase-DNA-binding protein 1 homolog, putative 0.0035 0.0108 0.1257
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.015 0.0698 0.9132
Trichomonas vaginalis conserved hypothetical protein 0.0091 0.0396 0.3439
Echinococcus granulosus peroxidasin 0.0026 0.0062 0.0136
Trypanosoma brucei calcium-transporting ATPase, putative 0.0048 0.0177 0.2242
Loa Loa (eye worm) hypothetical protein 0.0058 0.0229 0.1298
Trypanosoma brucei phosphatidylinositol 4-kinase, putative 0.0045 0.0159 0.2006
Brugia malayi hypothetical protein 0.0121 0.0549 0.3111
Loa Loa (eye worm) CXXC zinc finger family protein 0.0028 0.0077 0.0435
Brugia malayi calcium ATPase 0.0044 0.0155 0.0878
Echinococcus granulosus lamin 0.0027 0.0068 0.0149
Echinococcus multilocularis phosphatidylinositol 3 and 4 kinase 0.0015 0.0007 0.0008
Entamoeba histolytica plasma membrane calcium ion-transporting ATPase, putative 0.0067 0.0272 0.3827
Echinococcus granulosus GPCR family 2 0.0015 0.001 0.0015
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.0018 0.0025 0.0049
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0034 0.0107 0.0886
Trypanosoma cruzi cysteine proteinase, putative 0.004 0.0137 0.0196
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0049 0.0182 0.0263
Trypanosoma cruzi hypothetical protein, conserved 0.0035 0.0108 0.0151
Entamoeba histolytica cysteine protease, putative 0.0056 0.022 0.3019
Brugia malayi Melibiase family protein 0.0068 0.0278 0.1574
Echinococcus multilocularis ankyrin repeat and death domain containing protein 0.0014 0.0004 0.000000044333
Mycobacterium tuberculosis Probable nitrite reductase [NAD(P)H] large subunit [FAD flavoprotein] NirB 0.0323 0.1585 0.2158
Leishmania major cathepsin L-like protease 0.0056 0.022 0.2811
Loa Loa (eye worm) hypothetical protein 0.0062 0.025 0.1417
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.015 0.0698 0.9132
Echinococcus granulosus dihydrolipoamide dehydrogenase 0.0049 0.0182 0.0415
Trypanosoma brucei DNA polymerase kappa, putative 0.0061 0.0243 0.3114
Giardia lamblia Kinase, CMGC MAPK 0.0051 0.019 0.3232
Trypanosoma brucei hypothetical protein, conserved 0.0035 0.0108 0.1327
Trypanosoma brucei hypothetical protein, conserved 0.0023 0.005 0.0558
Trypanosoma cruzi phospholipid-transporting ATPase-like protein, putative 0.002 0.0033 0.0039
Trichomonas vaginalis mercuric reductase, putative 0.0049 0.0182 0.1547
Trypanosoma brucei DNA polymerase kappa, putative 0.0138 0.0636 0.8313
Trichomonas vaginalis conserved hypothetical protein 0.0018 0.0025 0.0156
Schistosoma mansoni hypothetical protein 0.0144 0.067 0.1551
Echinococcus granulosus terminal deoxycytidyl transferase rev1 0.0111 0.0501 0.1156
Toxoplasma gondii CMGC kinase, MAPK family (ERK) MAPK-1 0.0051 0.019 0.0669
Loa Loa (eye worm) hypothetical protein 0.0035 0.0108 0.061
Loa Loa (eye worm) hypothetical protein 0.0098 0.0431 0.2441
Plasmodium vivax vivapain-2 0.0056 0.022 0.2966
Schistosoma mansoni hypothetical protein 0.0015 0.001 0.0015
Echinococcus granulosus dna polymerase eta 0.0162 0.0763 0.1768
Onchocerca volvulus 0.0027 0.0068 0.0564
Mycobacterium tuberculosis Probable metal cation transporter P-type ATPase A CtpF 0.0046 0.0169 0.0168
Toxoplasma gondii ATP-dependent DNA helicase, RecQ family protein 0.0031 0.0089 0.0306
Giardia lamblia DNA damage repair protein 0.0035 0.0108 0.1625
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0056 0.022 0.1881
Chlamydia trachomatis metal transport ATPase 0.0032 0.0093 0.0043
Schistosoma mansoni chromodomain helicase DNA binding protein 0.0036 0.0116 0.0261
Brugia malayi Iron-sulfur cluster assembly accessory protein 0.0048 0.0176 0.0996
Trypanosoma cruzi target of rapamycin kinase 3 0.0035 0.0113 0.0158
Trypanosoma cruzi copper-transporting ATPase-like protein, putative 0.0032 0.0093 0.0128
Trichomonas vaginalis Clan CA, family C1, cathepsin L or K-like cysteine peptidase 0.0056 0.022 0.1881
Trichomonas vaginalis PIKK family atypical protein kinase 0.0033 0.0101 0.0825
Schistosoma mansoni hypothetical protein 0.0015 0.001 0.0015
Leishmania major copper-transporting ATPase-like protein, putative 0.0032 0.0093 0.113
Schistosoma mansoni copper ABC transporter ATPase 0.0032 0.0093 0.0207
Echinococcus granulosus sterol regulatory element binding protein 0.0042 0.0145 0.0329
Echinococcus granulosus cathepsin b 0.0018 0.0025 0.0049
Trichomonas vaginalis alpha-glucosidase, putative 0.0036 0.0114 0.0948
Echinococcus multilocularis neuropeptide receptor A26 0.0465 0.2311 0.537
Toxoplasma gondii target of rapamycin (TOR), putative 0.0033 0.0101 0.0348
Toxoplasma gondii cathepsin B 0.0018 0.0025 0.0074
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0056 0.022 0.1881
Entamoeba histolytica myb-like DNA-binding domain containing protein 0.0048 0.0175 0.2328
Leishmania major cathepsin L-like protease 0.0056 0.022 0.2811
Toxoplasma gondii LsmAD domain-containing protein 0.0051 0.0194 0.0686
Trichomonas vaginalis Clan CA, family C1, cathepsin H-like cysteine peptidase 0.0018 0.0025 0.0156
Onchocerca volvulus 0.0056 0.022 0.1906
Echinococcus granulosus ATP dependent DNA helicase Q1 0.0019 0.0029 0.0057
Echinococcus multilocularis Polycystic kidney disease protein 0.002 0.0031 0.0063
Mycobacterium tuberculosis Probable soluble pyridine nucleotide transhydrogenase SthA (STH) (NAD(P)(+) transhydrogenase [B-specific]) (nicotinamide nucleot 0.0049 0.0182 0.0186
Schistosoma mansoni peroxidasin 0.0026 0.0062 0.0136
Trypanosoma cruzi plasma membrane Ca2+ ATPase 0.011 0.0496 0.0735
Leishmania major cathepsin L-like protease 0.015 0.0698 0.9132
Onchocerca volvulus Cathepsin L homolog 0.0018 0.0025 0.0186
Plasmodium vivax copper-transporting ATPase, putative 0.0032 0.0093 0.1031
Loa Loa (eye worm) glycosyl hydrolase family 31 protein 0.0161 0.0758 0.4296
Toxoplasma gondii cathepsin CPL 0.0056 0.022 0.0779
Loa Loa (eye worm) follicle stimulating hormone receptor 0.0237 0.1143 0.6477
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.004 0.0137 0.1151
Chlamydia trachomatis phosphoshikimate 1-carboxyl vinyltransferase 0.0554 0.277 0.2733
Echinococcus granulosus copper transporting ATPase 1 0.0032 0.0093 0.0207
Onchocerca volvulus 0.0062 0.025 0.2171
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.004 0.0137 0.1151
Loa Loa (eye worm) hypothetical protein 0.0143 0.0663 0.3758
Loa Loa (eye worm) hypothetical protein 0.0014 0.0005 0.0026
Trypanosoma brucei hypothetical protein, conserved 0.0035 0.0108 0.1327
Brugia malayi hypothetical protein 0.0144 0.067 0.3799
Echinococcus granulosus chromodomain helicase DNA binding protein 4 0.0036 0.0116 0.0261
Loa Loa (eye worm) hypothetical protein 0.0049 0.0181 0.1028
Schistosoma mansoni smad1 5 8 and 0.0024 0.0056 0.0121
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0034 0.0107 0.0886
Schistosoma mansoni DNA helicase recq5 0.0019 0.0029 0.0057
Echinococcus granulosus lipoxygenase domain containing protein 0.002 0.0031 0.0063
Echinococcus multilocularis Smad4 0.0024 0.0056 0.0121
Echinococcus multilocularis survival motor neuron protein 1 0.0234 0.1131 0.2625
Entamoeba histolytica cysteine protease, putative 0.004 0.0137 0.1742
Leishmania major cathepsin L-like protease 0.0056 0.022 0.2811
Echinococcus multilocularis lysosomal alpha glucosidase 0.0161 0.0758 0.1756
Schistosoma mansoni smad1 5 8 and 0.0024 0.0056 0.0121
Echinococcus multilocularis cathepsin L 0.0018 0.0025 0.0049
Entamoeba histolytica cysteine proteinase, putative 0.0056 0.022 0.3019
Loa Loa (eye worm) hypothetical protein 0.0018 0.0025 0.0142
Brugia malayi Papain family cysteine protease containing protein 0.0018 0.0025 0.0142
Loa Loa (eye worm) MH1 domain-containing protein 0.0024 0.0056 0.0316
Trypanosoma cruzi mitogen activated protein kinase 2, putative 0.0051 0.019 0.0274
Brugia malayi hypothetical protein 0.0026 0.0062 0.0354
Schistosoma mansoni lipoxygenase 0.0055 0.0211 0.0483
Toxoplasma gondii 'chromo' (CHRromatin Organization MOdifier) domain-containing protein 0.0035 0.0108 0.0373
Trichomonas vaginalis Clan CA, family C1, cathepsin L, S or H-like cysteine peptidase 0.0018 0.0025 0.0156
Schistosoma mansoni chromobox protein-related (chromobox 1) (heterochromatin 1) 0.0035 0.0108 0.0242
Loa Loa (eye worm) hypothetical protein 0.0032 0.0093 0.0526
Trichomonas vaginalis MYB72, putative 0.0048 0.0175 0.1486
Schistosoma mansoni cpg binding protein 0.003 0.0085 0.0189
Loa Loa (eye worm) blistered cuticle protein 3 0.0026 0.0062 0.0354
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.015 0.0698 0.9132
Echinococcus multilocularis Ankyrin repeat domain containing protein 0.0089 0.0387 0.0892
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.015 0.0698 0.9132
Mycobacterium ulcerans cation transporter p-type ATPase a CtpA 0.0032 0.0093 0.0082
Loa Loa (eye worm) hypothetical protein 0.0026 0.0062 0.0354
Schistosoma mansoni cation-transporting atpase 13a1 (G-box binding protein) 0.0032 0.0093 0.0207
Schistosoma mansoni hypothetical protein 0.002 0.0031 0.0063
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0056 0.022 0.1881
Echinococcus multilocularis smad 0.0024 0.0056 0.0121
Schistosoma mansoni survival motor neuron protein 0.0048 0.0176 0.04
Trypanosoma cruzi cysteine peptidase, putative 0.015 0.0698 0.1039
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0056 0.022 0.1881
Trypanosoma cruzi cysteine proteinase, putative 0.004 0.0137 0.0196
Mycobacterium ulcerans UDP-N-acetylglucosamine 1-carboxyvinyltransferase 0.1966 1 1
Trypanosoma cruzi P-type H+-ATPase, putative 0.0064 0.0257 0.0376
Brugia malayi MH1 domain containing protein 0.0024 0.0056 0.0316
Leishmania major 2-oxoglutarate dehydrogenase, e3 component, lipoamidedehydrogenase-like protein 0.0049 0.0182 0.2312
Brugia malayi Cathepsin L-like precursor 0.0034 0.0107 0.0609
Schistosoma mansoni hypothetical protein 0.0405 0.2007 0.4664
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0049 0.0182 0.0263
Trichomonas vaginalis alpha-glucosidase, putative 0.0036 0.0114 0.0948
Loa Loa (eye worm) helicase 0.0035 0.0108 0.061
Schistosoma mansoni cathepsin F (C01 family) 0.0034 0.0107 0.0241
Loa Loa (eye worm) cytochrome P450 family protein 0.0016 0.0011 0.0064
Echinococcus multilocularis Chromo domain 0.0035 0.0108 0.0242
Echinococcus multilocularis cadherin EGF LAG seven pass G type receptor 0.0015 0.001 0.0015
Toxoplasma gondii phospholipid-translocating P-type ATPase, flippase subfamily protein 0.002 0.0033 0.0104
Entamoeba histolytica cysteine protease, putative 0.004 0.0137 0.1742
Loa Loa (eye worm) hypothetical protein 0.0035 0.0108 0.061
Trypanosoma cruzi hypothetical protein, conserved 0.0035 0.0108 0.0151
Entamoeba histolytica cysteine protease, putative 0.004 0.0137 0.1742
Leishmania major mitogen activated protein kinase, putative,map kinase, putative 0.0051 0.019 0.241
Echinococcus multilocularis phosphoserine phosphatase 0.002 0.0033 0.0069
Echinococcus granulosus Chromobox protein 3 0.0035 0.0108 0.0242
Onchocerca volvulus Cathepsin F homolog 0.0056 0.022 0.1906
Loa Loa (eye worm) hypothetical protein 0.0051 0.0194 0.1097
Mycobacterium tuberculosis Probable metal cation transporter P-type ATPase CtpV 0.0032 0.0093 0.0061
Loa Loa (eye worm) MH2 domain-containing protein 0.0358 0.1765 1
Echinococcus multilocularis chromobox protein 2 0.0035 0.0108 0.0242
Brugia malayi Niemann-Pick C1 protein precursor 0.0098 0.0431 0.2441
Entamoeba histolytica cysteine protease, putative 0.004 0.0137 0.1742
Trypanosoma brucei copper-transporting ATPase-like protein, putative 0.0032 0.0093 0.113
Echinococcus multilocularis Basic leucine zipper (bZIP) transcription factor 0.0081 0.0347 0.08
Onchocerca volvulus Huntingtin homolog 0.0121 0.0553 0.4844
Trichomonas vaginalis hypothetical protein 0.0035 0.0108 0.0887
Onchocerca volvulus Heterochromatin protein 1 homolog 0.0097 0.0427 0.3731
Echinococcus granulosus Basic leucine zipper bZIP transcription 0.0144 0.067 0.1551
Trypanosoma cruzi P-type H+-ATPase, putative 0.0064 0.0257 0.0376
Echinococcus multilocularis Ca2+ transporting ATPase plasma membrane 0.009 0.0394 0.0907
Echinococcus multilocularis lamin dm0 0.0027 0.0068 0.0149
Schistosoma mansoni alpha-galactosidase/alpha-n-acetylgalactosaminidase 0.0102 0.0451 0.1041
Trichomonas vaginalis conserved hypothetical protein 0.0056 0.0219 0.1874
Leishmania major P-type ATPase, putative 0.009 0.0394 0.5109
Trichomonas vaginalis Heterochromatin protein, putative 0.0035 0.0108 0.0887
Schistosoma mansoni transcription factor LCR-F1 0.0144 0.067 0.1551
Brugia malayi hypothetical protein 0.0124 0.0565 0.3199
Loa Loa (eye worm) hypothetical protein 0.0018 0.0025 0.0142
Loa Loa (eye worm) sodium potassium adenosine triphosphatase 0.0044 0.0155 0.0878
Mycobacterium ulcerans metal cation-transporting p-type ATPase F, CtpF 0.0147 0.0682 0.0671
Echinococcus multilocularis cathepsin b 0.0018 0.0025 0.0049
Brugia malayi Cathepsin L-like precursor 0.0056 0.022 0.1246
Schistosoma mansoni Smad4 0.0024 0.0056 0.0121
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0037 0.0123 0.1023
Echinococcus multilocularis lamin 0.0027 0.0068 0.0149
Trypanosoma brucei cation-transporting ATPase, putative 0.0032 0.0093 0.113
Trypanosoma brucei FAT domain/Rapamycin binding domain/Phosphatidylinositol 3- and 4-kinase, putative 0.0019 0.0026 0.0241
Mycobacterium tuberculosis Probable oxidoreductase 0.0359 0.1769 0.2418
Giardia lamblia GTOR 0.0045 0.0159 0.2632
Trichomonas vaginalis plasma membrane calcium-transporting ATPase, putative 0.011 0.0496 0.4326
Loa Loa (eye worm) hypothetical protein 0.0026 0.0062 0.0354
Toxoplasma gondii calcium-translocating P-type ATPase, PMCA-type protein 0.011 0.0496 0.1777
Trichomonas vaginalis PIKK family atypical protein kinase 0.0033 0.0101 0.0825
Brugia malayi follicle stimulating hormone receptor 0.0237 0.1143 0.6477
Schistosoma mansoni plasma membrane calcium-transporting atpase 0.009 0.0394 0.0907
Brugia malayi RNA binding protein 0.0062 0.0249 0.1413
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.015 0.0698 0.9132
Trypanosoma cruzi cytochrome P450, putative 0.0016 0.0011 0.0006
Trypanosoma cruzi DNA polymerase kappa, putative 0.0138 0.0636 0.0946
Trichomonas vaginalis PIKK family atypical protein kinase 0.0024 0.0054 0.0413
Trichomonas vaginalis chromobox protein, putative 0.0153 0.0715 0.6265
Echinococcus granulosus phosphatidylinositol 3 and 4 kinase 0.0015 0.0007 0.0008
Loa Loa (eye worm) hypothetical protein 0.0034 0.0107 0.0609
Brugia malayi hypothetical protein 0.002 0.0031 0.0176
Trypanosoma cruzi cysteine peptidase, putative 0.1312 0.6651 1
Onchocerca volvulus 0.0056 0.022 0.1906
Loa Loa (eye worm) papain family cysteine protease containing protein 0.0018 0.0025 0.0142
Entamoeba histolytica cysteine protease, putative 0.004 0.0137 0.1742
Echinococcus multilocularis dna polymerase kappa 0.0138 0.0636 0.1471
Loa Loa (eye worm) cytochrome P450 family protein 0.0016 0.0011 0.0064
Trypanosoma brucei DNA polymerase kappa, putative 0.0138 0.0636 0.8313
Trypanosoma brucei dihydrolipoamide dehydrogenase, point mutation 0.0049 0.0182 0.2312
Brugia malayi Protein kinase domain containing protein 0.0015 0.0006 0.0035
Toxoplasma gondii sarco/endoplasmic reticulum Ca2+-ATPase 0.0147 0.0682 0.245
Entamoeba histolytica Plasma membrane calcium-transporting ATPase, putative 0.011 0.0496 0.7298
Entamoeba histolytica phospholipid-transporting P-type ATPase, putative 0.0032 0.0093 0.105
Schistosoma mansoni TGF-beta signal transducer Smad2 0.0024 0.0056 0.0121
Entamoeba histolytica plasma membrane calcium ion-transporting ATPase, putative 0.0054 0.0207 0.282
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0056 0.022 0.1881
Leishmania major cathepsin L-like protease 0.015 0.0698 0.9132
Loa Loa (eye worm) hypothetical protein 0.0026 0.0062 0.0354
Brugia malayi cathepsin Z-like cysteine proteinase 0.0018 0.0025 0.0142
Echinococcus multilocularis Ataxin 2, N terminal,domain containing protein 0.0023 0.0049 0.0105
Schistosoma mansoni lamin 0.0027 0.0068 0.0149
Trichomonas vaginalis r2r3-MYB transcription factor, putative 0.0048 0.0175 0.1486
Onchocerca volvulus Dual oxidase homolog 0.0026 0.0062 0.0517
Brugia malayi ATP-dependent DNA helicase, RecQ family protein 0.0019 0.0029 0.0162
Brugia malayi intermediate filament protein 0.0027 0.0068 0.0384
Echinococcus multilocularis dna polymerase eta 0.0162 0.0763 0.1768
Toxoplasma gondii melibiase subfamily protein 0.0102 0.0451 0.1614
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0035 0.0108 0.0887
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0056 0.022 0.1881
Plasmodium vivax dihydrolipoyl dehydrogenase, apicoplast, putative 0.0049 0.0182 0.2391
Trypanosoma cruzi cruzipain precursor, putative 0.015 0.0698 0.1039
Echinococcus granulosus Na:K ATPase alpha subunit 0.008 0.0341 0.0786
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0049 0.0182 0.0263
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.015 0.0698 0.9132
Echinococcus multilocularis terminal deoxycytidyl transferase rev1 0.0111 0.0501 0.1156
Trichomonas vaginalis alpha-glucosidase, putative 0.0036 0.0114 0.0948
Loa Loa (eye worm) hypothetical protein 0.0018 0.0025 0.0142
Brugia malayi Cathepsin L-like precursor 0.0056 0.022 0.1246
Trypanosoma cruzi cysteine peptidase, putative 0.015 0.0698 0.1039
Trichomonas vaginalis PIKK family atypical protein kinase 0.003 0.0084 0.0678
Echinococcus multilocularis cathepsin L cysteine protease 0.0056 0.022 0.0503
Brugia malayi Latrophilin receptor protein 2 0.0015 0.001 0.0058
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.0018 0.0025 0.0049
Loa Loa (eye worm) hypothetical protein 0.0026 0.0065 0.037
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0041 0.0141 0.118
Plasmodium falciparum thioredoxin reductase 0.0142 0.0656 0.9602
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0056 0.022 0.1881
Brugia malayi cathepsin L precursor 0.0018 0.0025 0.0142
Echinococcus granulosus arachidonate 5 lipoxygenase 0.0055 0.0211 0.0483
Loa Loa (eye worm) latrophilin receptor protein 2 0.0015 0.001 0.0058
Trichomonas vaginalis PIKK family atypical protein kinase 0.0033 0.0101 0.0825
Trypanosoma cruzi cytochrome P450, putative 0.0016 0.0011 0.0006
Loa Loa (eye worm) hypothetical protein 0.0314 0.1542 0.8736
Schistosoma mansoni hypothetical protein 0.004 0.0138 0.0311
Mycobacterium tuberculosis Probable UDP-N-acetylglucosamine 1-carboxyvinyltransferase MurA 0.1412 0.7161 1
Trichomonas vaginalis plasma membrane calcium-transporting ATPase, putative 0.011 0.0496 0.4326
Entamoeba histolytica cysteine proteinase, putative 0.0056 0.022 0.3019
Loa Loa (eye worm) hypothetical protein 0.0032 0.0095 0.0541
Echinococcus multilocularis protein dispatched 1 0.0048 0.0176 0.04
Trypanosoma brucei unspecified product 0.0077 0.0324 0.4187
Echinococcus multilocularis RUN 0.002 0.0031 0.0063
Brugia malayi Type III restriction enzyme, res subunit family protein 0.0035 0.0108 0.061
Trichomonas vaginalis plasma membrane calcium-transporting ATPase, putative 0.009 0.0394 0.3419
Trichomonas vaginalis PIKK family atypical protein kinase 0.0033 0.0101 0.0825
Toxoplasma gondii cathepsin CPC1 0.0018 0.0025 0.0074
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0049 0.0182 0.0263
Brugia malayi CHE-14 protein 0.0042 0.0145 0.0824
Trichomonas vaginalis neutral alpha-glucosidase ab precursor, putative 0.0036 0.0114 0.0948
Brugia malayi Phosphatidylinositol 3- and 4-kinase family protein 0.0045 0.0159 0.0901
Trypanosoma brucei DNA polymerase kappa, putative 0.0083 0.0357 0.463
Trypanosoma cruzi copper-transporting ATPase, putative 0.002 0.0033 0.0039
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0041 0.0141 0.118
Trichomonas vaginalis pc-MYB2, putative 0.0048 0.0175 0.1486
Leishmania major cathepsin L-like protease 0.0056 0.022 0.2811
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0018 0.0025 0.0156
Trypanosoma brucei DNA polymerase eta, putative 0.0162 0.0763 1
Entamoeba histolytica cysteine protease, putative 0.004 0.0137 0.1742
Onchocerca volvulus 0.0056 0.022 0.1906
Echinococcus multilocularis dnaJ subfamily B 0.0405 0.2007 0.4664
Entamoeba histolytica deoxycytidyl transferase, putative 0.0111 0.0501 0.7371
Echinococcus multilocularis phospholipid transporting ATPase IIB 0.0032 0.0093 0.0207
Trichomonas vaginalis C-MYB, putative 0.0048 0.0175 0.1486
Trypanosoma brucei DNA polymerase kappa, putative 0.0061 0.0243 0.3114
Entamoeba histolytica cysteine proteinase, putative 0.004 0.0137 0.1742
Trypanosoma brucei DNA polymerase kappa, putative 0.0138 0.0636 0.8313
Echinococcus granulosus ankyrin repeat and death domain containing protein 0.0014 0.0004 0.000000044333
Trichomonas vaginalis sucrase-isomaltase, putative 0.0036 0.0114 0.0948
Loa Loa (eye worm) hypothetical protein 0.0027 0.0068 0.0384
Trichomonas vaginalis plasma membrane calcium-transporting ATPase, putative 0.011 0.0496 0.4326
Trichomonas vaginalis r2r3-MYB transcription factor, putative 0.0048 0.0176 0.1497
Schistosoma mansoni tar DNA-binding protein 0.0062 0.0249 0.0571
Schistosoma mansoni phosphoserine phosphatase 0.002 0.0033 0.0069
Plasmodium vivax cation transporting ATPase, putative 0.0032 0.0093 0.1031
Loa Loa (eye worm) hypothetical protein 0.0034 0.0107 0.0609
Brugia malayi potential phospholipid-transporting ATPase IIB, putative 0.0032 0.0093 0.0526
Echinococcus multilocularis phosphoserine phosphatase 0.002 0.0033 0.0069
Echinococcus granulosus chromodomain helicase DNA binding protein 1 0.0035 0.0108 0.0242
Schistosoma mansoni multiple ankyrin repeats single kh domain protein 0.0089 0.0387 0.0892
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0041 0.0141 0.118
Brugia malayi Na,K-ATPase alpha subunit 0.01 0.0444 0.2515
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0056 0.022 0.1881
Mycobacterium ulcerans hypothetical protein 0.0035 0.0108 0.0097
Echinococcus multilocularis chromodomain helicase DNA binding protein 1 0.0035 0.0108 0.0242
Toxoplasma gondii P-type ATPase4, putative 0.01 0.0444 0.1589
Entamoeba histolytica cysteine protease, putative 0.004 0.0137 0.1742
Trypanosoma brucei calcium motive p-type ATPase, putative 0.008 0.0341 0.4419
Echinococcus multilocularis cation transporting ATPase 13A3 0.0032 0.0093 0.0207
Loa Loa (eye worm) Na,K-ATPase alpha subunit 0.01 0.0444 0.2515
Plasmodium vivax SET domain protein, putative 0.003 0.0086 0.0923
Echinococcus multilocularis FKBP12 rapamycin complex associated protein 0.0045 0.0159 0.0361
Echinococcus granulosus cathepsin l1 0.0034 0.0107 0.0241
Schistosoma mansoni subfamily C1A non-peptidase homologue (C01 family) 0.0018 0.0025 0.0049
Plasmodium falciparum copper-transporting ATPase 0.0032 0.0093 0.1031
Plasmodium falciparum holo-[acyl-carrier-protein] synthase, putative 0.0023 0.005 0.0374
Toxoplasma gondii histone lysine methyltransferase SET1 0.0055 0.0213 0.0753
Plasmodium vivax thioredoxin reductase, putative 0.0142 0.0656 0.9602
Trypanosoma cruzi proton motive ATPase 1, putative 0.002 0.0033 0.0039
Loa Loa (eye worm) hypothetical protein 0.0026 0.0062 0.0354
Toxoplasma gondii haloacid dehalogenase family hydrolase domain-containing protein 0.002 0.0033 0.0104
Trichomonas vaginalis Clan CA, family C1, cathepsin B-like cysteine peptidase 0.0018 0.0025 0.0156
Schistosoma mansoni tar DNA-binding protein 0.0062 0.0249 0.0571
Schistosoma mansoni Na+/K+ transporting ATPase subunit alpha 0.01 0.0444 0.1024
Schistosoma mansoni alpha-galactosidase/alpha-n-acetylgalactosaminidase 0.0014 0.0005 0.0001
Toxoplasma gondii P-type ATPase PMA1 0.0064 0.0257 0.0914
Loa Loa (eye worm) hypothetical protein 0.0032 0.0093 0.0526
Trichomonas vaginalis PIKK family atypical protein kinase 0.0033 0.0101 0.0825
Plasmodium falciparum non-SERCA-type Ca2+ -transporting P-ATPase 0.0147 0.0682 1
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0041 0.0141 0.118
Trypanosoma cruzi Phosphatidylinositol 3-kinase tor2 0.0045 0.0159 0.0228
Loa Loa (eye worm) ATP-dependent DNA helicase 0.0019 0.0029 0.0162
Plasmodium falciparum dihydrolipoyl dehydrogenase, mitochondrial 0.0049 0.0182 0.2391
Entamoeba histolytica hypothetical protein 0.0023 0.005 0.0381
Loa Loa (eye worm) glutathione reductase 0.0142 0.0656 0.3717
Loa Loa (eye worm) fibroinase 0.0056 0.022 0.1246
Echinococcus multilocularis phosphoserine phosphatase 0.002 0.0033 0.0069
Loa Loa (eye worm) hypothetical protein 0.0022 0.0043 0.0245
Echinococcus granulosus mitogen activated protein kinase 3 0.0051 0.019 0.0432
Trichomonas vaginalis neutral alpha-glucosidase ab precursor, putative 0.0036 0.0114 0.0948
Loa Loa (eye worm) hypothetical protein 0.0079 0.0336 0.1904
Trichomonas vaginalis conserved hypothetical protein 0.0035 0.0108 0.0887
Toxoplasma gondii E1-E2 ATPase subfamily protein 0.0044 0.0155 0.0544
Brugia malayi Cathepsin L-like precursor 0.0056 0.022 0.1246
Plasmodium falciparum ataxin-2 like protein, putative 0.0051 0.0194 0.2577
Schistosoma mansoni cathepsin S (C01 family) 0.0018 0.0025 0.0049
Onchocerca volvulus 0.0026 0.0062 0.0517
Giardia lamblia Copper-transporting P-type ATPase 0.0032 0.0093 0.1331
Trypanosoma cruzi DNA polymerase eta, putative 0.0162 0.0763 0.1138
Schistosoma mansoni ankyrin 23/unc44 0.0014 0.0004 0.000000044333
Echinococcus multilocularis Tetracycline resistance leader peptide, TetL 0.011 0.0496 0.1146
Trypanosoma brucei cytochrome P450, putative 0.0016 0.0011 0.0052
Brugia malayi Probable cation-transporting ATPase C10C6.6 in chromosome IV 0.0032 0.0093 0.0526
Trichomonas vaginalis PIKK family atypical protein kinase 0.0045 0.0159 0.1343
Echinococcus granulosus intermediate filament protein 0.0027 0.0068 0.0149
Leishmania major vacuolar-type Ca2 -ATPase, putative 0.011 0.0496 0.6464
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0049 0.0182 0.0263
Mycobacterium tuberculosis Possible DNA-damage-inducible protein P DinP (DNA polymerase V) (pol IV 2) (DNA nucleotidyltransferase (DNA-directed)) 0.0118 0.0534 0.0681
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0056 0.022 0.1881
Onchocerca volvulus Chorion peroxidase homolog 0.0026 0.0062 0.0517
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.0018 0.0025 0.0049
Toxoplasma gondii 4'-phosphopantetheinyl transferase domain-containing protein 0.0023 0.005 0.0163
Onchocerca volvulus Peroxidase homolog 0.0026 0.0062 0.0517
Echinococcus granulosus cation transporting ATPase 13A3 0.0032 0.0093 0.0207
Trichomonas vaginalis conserved hypothetical protein 0.0035 0.0108 0.0887
Mycobacterium ulcerans metal cation transporter ATPase p-type CtpE 0.0032 0.0093 0.0082
Schistosoma mansoni niemann-pick C1 (NPC1) 0.0099 0.0438 0.1012
Echinococcus granulosus nuclear factor of activated T cells 5 0.0073 0.0305 0.07
Loa Loa (eye worm) hypothetical protein 0.0026 0.0062 0.0354
Plasmodium vivax P-type ATPase4, putative 0.0147 0.0682 1
Echinococcus granulosus ATP dependent DNA helicase Q5 0.0019 0.0029 0.0057
Schistosoma mansoni alpha-glucosidase 0.0139 0.0643 0.1487
Plasmodium falciparum LCCL domain-containing protein 0.002 0.0031 0.0091
Onchocerca volvulus 0.0056 0.022 0.1906
Trypanosoma cruzi ATP-dependent DEAD/H DNA helicase recQ, putative 0.0025 0.0057 0.0075
Schistosoma mansoni cpg binding protein 0.003 0.0085 0.0189
Echinococcus granulosus Polycystic kidney disease protein 0.002 0.0031 0.0063
Echinococcus multilocularis histone lysine methyltransferase setb histone lysine methyltransferase eggless 0.003 0.0086 0.019
Loa Loa (eye worm) calcium ATPase 0.0022 0.0043 0.0241
Plasmodium falciparum thioredoxin reductase 0.0049 0.0182 0.2391
Trypanosoma cruzi major cysteine proteinase, putative 0.0018 0.0025 0.0027
Schistosoma mansoni loxhd1 0.002 0.0031 0.0063
Loa Loa (eye worm) animal heme peroxidase 0.0026 0.0062 0.0354
Brugia malayi MH2 domain containing protein 0.0024 0.0056 0.0316
Mycobacterium leprae PROBABLE CATION-TRANSPORTER P-TYPE ATPASE B CTPB 0.0032 0.0093 0.0061
Echinococcus granulosus X box binding protein 1 0.0286 0.1394 0.3235
Schistosoma mansoni alpha-galactosidase/alpha-n-acetylgalactosaminidase 0.0102 0.0451 0.1041
Loa Loa (eye worm) heterochromatin protein 1 0.0153 0.0715 0.4051
Loa Loa (eye worm) hypothetical protein 0.003 0.0086 0.0485
Brugia malayi Uncoordinated protein 44 0.0014 0.0004 0.0022
Loa Loa (eye worm) intermediate filament protein 0.0027 0.0068 0.0384
Toxoplasma gondii ImpB/MucB/SamB family protein 0.0086 0.037 0.1323
Mycobacterium ulcerans cation transporter p-type ATPase D CtpD 0.0032 0.0093 0.0082
Brugia malayi Cathepsin L-like precursor 0.0022 0.0043 0.0245
Loa Loa (eye worm) hypothetical protein 0.0022 0.0043 0.0245
Entamoeba histolytica cation-transporting P-typeATPase, putative 0.0032 0.0093 0.105
Echinococcus multilocularis X box binding protein 1 0.0286 0.1394 0.3235
Schistosoma mansoni hypothetical protein 0.0015 0.001 0.0015
Trypanosoma cruzi DNA polymerase kappa, putative 0.0138 0.0636 0.0946
Schistosoma mansoni hypothetical protein 0.0853 0.43 1
Entamoeba histolytica myb-like DNA-binding domain containing protein 0.0048 0.0175 0.2328
Entamoeba histolytica cysteine protease, putative 0.004 0.0137 0.1742
Trichomonas vaginalis CMGC family protein kinase 0.0051 0.019 0.1613
Loa Loa (eye worm) sodium/potassium-transporting ATPase subunit alpha 0.0068 0.0279 0.1583
Loa Loa (eye worm) ctsf protein 0.0056 0.022 0.1246
Brugia malayi Sodium/potassium-transporting ATPase alpha chain, putative 0.0068 0.0279 0.1583
Loa Loa (eye worm) hypothetical protein 0.0121 0.0553 0.3133
Trypanosoma cruzi cysteine peptidase C (CPC), putative 0.0018 0.0025 0.0027
Trichomonas vaginalis DNA helicase recq, putative 0.0025 0.0057 0.0442
Mycobacterium tuberculosis Probable membrane NADH dehydrogenase NdhA 0.0323 0.1585 0.2158
Loa Loa (eye worm) RNA recognition domain-containing protein domain-containing protein 0.0062 0.0249 0.1413
Onchocerca volvulus 0.0064 0.0258 0.2242
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.015 0.0698 0.9132
Echinococcus multilocularis lipoxygenase domain containing protein 0.002 0.0031 0.0063
Echinococcus multilocularis Basic leucine zipper (bZIP) transcription 0.0144 0.067 0.1551
Loa Loa (eye worm) hypothetical protein 0.0079 0.0334 0.189
Trypanosoma brucei DNA polymerase kappa, putative 0.0118 0.0534 0.697
Loa Loa (eye worm) hypothetical protein 0.0124 0.0564 0.3196
Trypanosoma brucei unspecified product 0.0131 0.0602 0.7869
Brugia malayi MH1 domain containing protein 0.0024 0.0056 0.0316
Loa Loa (eye worm) cytochrome P450 family protein 0.0026 0.0064 0.0361
Echinococcus multilocularis Ankyrin 0.0014 0.0005 0.0001
Plasmodium falciparum conserved Plasmodium protein, unknown function 0.0035 0.0108 0.1257
Echinococcus multilocularis ATP dependent DNA helicase Q1 0.0019 0.0029 0.0057
Trichomonas vaginalis Clan CA, family C1, cathepsin L or H-like cysteine peptidase 0.0018 0.0025 0.0156
Plasmodium vivax hypothetical protein, conserved 0.0035 0.0108 0.1257
Schistosoma mansoni peroxidasin 0.0026 0.0062 0.0136
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.0018 0.0025 0.0049
Plasmodium vivax vivapain-3 0.004 0.0137 0.1711
Mycobacterium tuberculosis NAD(P)H quinone reductase LpdA 0.0359 0.1769 0.2418
Loa Loa (eye worm) cathepsin B 0.0018 0.0025 0.0142
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.003 0.0086 0.019
Loa Loa (eye worm) hypothetical protein 0.0068 0.0278 0.1574
Trypanosoma brucei vacuolar-type Ca2+-ATPase 2 0.011 0.0496 0.6464
Echinococcus granulosus Niemann Pick C1 protein 0.0139 0.0645 0.1493
Toxoplasma gondii heavy metal translocating P-type ATPase subfamily protein 0.0032 0.0093 0.0319
Schistosoma mansoni histone-lysine n-methyltransferase suv9 0.0065 0.0262 0.0602
Trichomonas vaginalis conserved hypothetical protein 0.0035 0.0108 0.0887
Leishmania major cathepsin L-like protease 0.015 0.0698 0.9132
Echinococcus multilocularis calcium transporting ATPase type 2C member 0.0147 0.0682 0.1579
Brugia malayi bZIP transcription factor family protein 0.0081 0.0347 0.1969
Leishmania major cytochrome p450-like protein 0.0016 0.0011 0.0052
Brugia malayi fibroinase precursor 0.0018 0.0025 0.0142
Loa Loa (eye worm) hypothetical protein 0.002 0.0031 0.0176
Trypanosoma brucei DNA polymerase kappa, putative 0.0138 0.0636 0.8313
Loa Loa (eye worm) intermediate filament tail domain-containing protein 0.0027 0.0068 0.0384
Echinococcus multilocularis musashi 0.0027 0.0068 0.0149
Loa Loa (eye worm) hypothetical protein 0.0034 0.0107 0.0609
Trypanosoma cruzi trypanothione reductase, putative 0.0049 0.0182 0.0263
Brugia malayi hypothetical protein 0.002 0.0031 0.0176
Trichomonas vaginalis r2r3-MYB transcription factor, putative 0.0048 0.0176 0.1497
Schistosoma mansoni terminal deoxycytidyl transferase 0.0111 0.0501 0.1156
Brugia malayi cathepsin Z-like cysteine proteinase 0.0018 0.0025 0.0142
Leishmania major mitogen activated protein kinase 4, putative;with=GeneDB:LmxM19.1440 0.0051 0.019 0.241
Loa Loa (eye worm) abnormal chemotaxis protein 14 0.0042 0.0145 0.0824
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0056 0.022 0.1881
Trichomonas vaginalis CMGC family protein kinase 0.0051 0.019 0.1613
Trichomonas vaginalis cation-transporting ATPase fungi, putative 0.011 0.0496 0.4326
Echinococcus granulosus Chromo domain 0.0035 0.0108 0.0242
Trichomonas vaginalis PIKK family atypical protein kinase 0.0029 0.0079 0.0634
Toxoplasma gondii ATP-dependent DNA helicase, RecQ family protein 0.0019 0.0029 0.0087
Brugia malayi Phosphatidylinositol 3- and 4-kinase family protein 0.0015 0.0007 0.0042
Brugia malayi hypothetical protein 0.0051 0.0194 0.1101
Plasmodium vivax glutathione reductase, putative 0.0142 0.0656 0.9602
Trichomonas vaginalis cation-transporting ATPase, putative 0.0147 0.0682 0.5974
Entamoeba histolytica phospholipid-transporting P-type ATPase, putative 0.0032 0.0093 0.105
Brugia malayi Cathepsin L-like precursor 0.0056 0.022 0.1246
Echinococcus multilocularis expressed conserved protein 0.0092 0.04 0.0923
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0035 0.0108 0.0887
Loa Loa (eye worm) RecQ helicase 0.0046 0.0168 0.0949
Schistosoma mansoni SmCL2-like peptidase (C01 family) 0.004 0.0137 0.0311
Loa Loa (eye worm) glycosyl hydrolase family 31 protein 0.0036 0.0114 0.0649
Leishmania major phosphopantetheinyl transferase-like protein 0.0023 0.005 0.0558
Loa Loa (eye worm) hypothetical protein 0.0022 0.0043 0.0245
Onchocerca volvulus Huntingtin homolog 0.0121 0.0553 0.4844
Trypanosoma brucei phosphatidylinositol 3-kinase tor, putative 0.0021 0.0039 0.0415
Trichomonas vaginalis conserved hypothetical protein 0.0035 0.0108 0.0887
Echinococcus granulosus mothers against decapentaplegic 5 0.0024 0.0056 0.0121
Trichomonas vaginalis conserved hypothetical protein 0.0091 0.0396 0.3439
Schistosoma mansoni calcium-transporting atpase sarcoplasmic/endoplasmic reticulum type (calcium pump) 0.0127 0.058 0.134
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.0018 0.0025 0.0049
Brugia malayi hypothetical protein 0.0033 0.0101 0.0572
Echinococcus granulosus cathepsin L 0.0018 0.0025 0.0049
Trypanosoma brucei protein kinase, putative 0.0051 0.019 0.241
Entamoeba histolytica myb-like DNA-binding domain containing protein 0.0048 0.0175 0.2328
Plasmodium vivax dihydrolipoyl dehydrogenase, mitochondrial, putative 0.0049 0.0182 0.2391
Echinococcus granulosus cadherin EGF LAG seven pass G type receptor 0.0015 0.001 0.0015
Echinococcus granulosus neutral alpha glucosidase AB 0.0036 0.0114 0.0257
Toxoplasma gondii 4'-phosphopantetheinyl transferase superfamily protein 0.0023 0.005 0.0163
Trichomonas vaginalis chromobox protein, putative 0.0035 0.0108 0.0887
Trypanosoma cruzi calcium motive p-type ATPase, putative 0.008 0.0341 0.0503
Trypanosoma cruzi cysteine peptidase, clan CA, family C1, cathepsin L-like, putative 0.0128 0.0585 0.087
Mycobacterium ulcerans dihydrolipoamide dehydrogenase, LpdB 0.0049 0.0182 0.0171
Leishmania major ATP-dependent DEAD/H DNA helicase recQ, putative 0.0025 0.0057 0.066
Trypanosoma cruzi DNA polymerase eta, putative 0.0086 0.037 0.0546
Trypanosoma cruzi copper-transporting ATPase-like protein, putative 0.002 0.0033 0.0039
Echinococcus granulosus Protein patched homolog 1 0.0042 0.0145 0.0329
Echinococcus granulosus tar DNA binding protein 0.0062 0.0249 0.0571
Trypanosoma brucei DNA damage repair protein, putative 0.0035 0.0108 0.1327
Trypanosoma cruzi dihydrolipoyl dehydrogenase, putative 0.0049 0.0182 0.0263
Trichomonas vaginalis Clan CA, family C1, cathepsin L or K-like cysteine peptidase 0.0056 0.022 0.1881
Schistosoma mansoni lamin 0.0027 0.0068 0.0149
Schistosoma mansoni cellular tumor antigen P53 0.0049 0.0182 0.0415
Loa Loa (eye worm) pre-SET domain-containing protein family protein 0.0207 0.0991 0.5614
Trichomonas vaginalis DNA helicase recq, putative 0.0046 0.0168 0.1418
Entamoeba histolytica recQ family helicase, putative 0.0025 0.0057 0.0501
Plasmodium vivax ADP-dependent DNA helicase RecQ, putative 0.0031 0.0091 0.1003
Loa Loa (eye worm) animal heme peroxidase 0.0026 0.0062 0.0354
Mycobacterium leprae Probable metal cation-transporting P-type ATPase C CtpC 0.0032 0.0093 0.0061
Echinococcus granulosus Niemann Pick C1 protein 0.0098 0.0431 0.0994
Brugia malayi Papain family cysteine protease containing protein 0.0056 0.022 0.1246
Echinococcus granulosus lamin dm0 0.0027 0.0068 0.0149
Echinococcus granulosus phospholipid transporting ATPase VA 0.002 0.0033 0.0069
Brugia malayi hypothetical protein 0.0121 0.0553 0.3133
Trichomonas vaginalis PIKK family atypical protein kinase 0.0035 0.0112 0.0929
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0041 0.0141 0.118
Brugia malayi Blistered cuticle protein 3 0.0026 0.0062 0.0354
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0056 0.022 0.1881
Loa Loa (eye worm) hypothetical protein 0.0026 0.0062 0.0354
Trichomonas vaginalis conserved hypothetical protein 0.0018 0.0025 0.0156
Giardia lamblia Myb 1-like protein 0.0048 0.0176 0.2973
Brugia malayi M-phase phosphoprotein, mpp8 0.0124 0.0564 0.3196
Brugia malayi dihydrolipoyl dehydrogenase, mitochondrial precursor, putative 0.0049 0.0182 0.1032
Trypanosoma brucei DNA polymerase IV, putative 0.0138 0.0636 0.8313
Toxoplasma gondii glycosyl hydrolase, family 31 protein 0.0036 0.0114 0.0398
Brugia malayi Glycosyl hydrolases family 31 protein 0.0036 0.0114 0.0649
Echinococcus granulosus cathepsin L cysteine proteinase 0.0056 0.022 0.0503
Trypanosoma cruzi PAB1-binding protein , putative 0.0051 0.0194 0.0281
Loa Loa (eye worm) calcium-transporting ATPase sarcoplasmic/endoplasmic reticulum type 0.0095 0.0415 0.2352
Mycobacterium leprae PROBABLE NADH DEHYDROGENASE NDH 0.0323 0.1585 0.2158
Echinococcus multilocularis Niemann Pick C1 protein 0.0139 0.0645 0.1493
Brugia malayi Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain containing protein 0.0036 0.0115 0.0654
Brugia malayi Corticotropin releasing factor receptor 2 precursor, putative 0.0049 0.0181 0.1028
Loa Loa (eye worm) cysteine proteinase cathepsin Z 0.0018 0.0025 0.0142
Loa Loa (eye worm) Papain cysteine protease/cathepsin propeptide inhibitor-containing protein 0.0056 0.022 0.1246
Trichomonas vaginalis PIKK family atypical protein kinase 0.0026 0.0066 0.0518
Trichomonas vaginalis Clan CA, family C1, cathepsin B-like cysteine peptidase 0.0018 0.0025 0.0156
Echinococcus granulosus Ankyrin 0.0014 0.0005 0.0001
Onchocerca volvulus 0.0056 0.022 0.1906
Trichomonas vaginalis cation-transporting ATPase, putative 0.0032 0.0093 0.0756
Echinococcus multilocularis cathepsin b 0.0018 0.0025 0.0049
Toxoplasma gondii cation-transporting atpase family protein 0.002 0.0033 0.0104
Loa Loa (eye worm) Smad1 0.0024 0.0056 0.0316
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.0018 0.0025 0.0049
Trypanosoma cruzi DNA damage repair protein, putative 0.0035 0.0108 0.0151
Plasmodium vivax vivapain-2 0.0056 0.022 0.2966
Toxoplasma gondii Myb family DNA-binding domain-containing protein 0.0048 0.0176 0.0622
Mycobacterium leprae PROBABLE UDP-N-ACETYLGLUCOSAMINE 1-CARBOXYVINYLTRANSFERASE MURA 0.1412 0.7161 1
Entamoeba histolytica chromodomain-helicase-DNA-binding protein, putative 0.0035 0.0108 0.128
Brugia malayi hypothetical protein 0.0234 0.1131 0.6412
Schistosoma mansoni polycystin 1-related 0.002 0.0031 0.0063
Trichomonas vaginalis PIKK family atypical protein kinase 0.0024 0.0054 0.0412
Brugia malayi alpha keto acid dehydrogenase complex, E3 component, lipoamide dehydrogenase 0.0036 0.0115 0.0654
Mycobacterium ulcerans flavoprotein disulfide reductase 0.0049 0.0182 0.0171
Brugia malayi Intermediate filament tail domain containing protein 0.0027 0.0068 0.0384

Activities

Activity type Activity value Assay description Source Reference
Inhibition (binding) = 18 % Inhibition of SIRT2 at 200 uM ChEMBL. 17181175
Inhibition (binding) = 18 % Inhibition of SIRT2 at 200 uM ChEMBL. 17181175

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
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External resources for this compound

No external resources registered for this compound

Bibliographic References

1 literature reference was collected for this gene.

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