Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Plasmodium falciparum | cysteine proteinase falcipain 3 | 0.0423 | 1 | 1 |
Plasmodium vivax | vivapain-2 | 0.0423 | 1 | 1 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0423 | 1 | 1 |
Entamoeba histolytica | cysteine proteinase, putative | 0.0283 | 0.5061 | 0.3182 |
Loa Loa (eye worm) | hypothetical protein | 0.0283 | 0.5061 | 0.5061 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L or K-like cysteine peptidase | 0.0423 | 1 | 1 |
Plasmodium vivax | vivapain-3 | 0.0218 | 0.2757 | 0.2757 |
Schistosoma mansoni | cathepsin F (C01 family) | 0.0423 | 1 | 1 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0423 | 1 | 1 |
Onchocerca volvulus | Cathepsin F homolog | 0.0423 | 1 | 1 |
Leishmania major | cysteine peptidase A (CPA) | 0.0423 | 1 | 0.5 |
Schistosoma mansoni | SmCL2-like peptidase (C01 family) | 0.0218 | 0.2757 | 0.2757 |
Schistosoma mansoni | cathepsin F (C01 family) | 0.0283 | 0.5061 | 0.5061 |
Echinococcus granulosus | cathepsin L cysteine proteinase | 0.0423 | 1 | 1 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.0423 | 1 | 1 |
Onchocerca volvulus | 0.0423 | 1 | 1 | |
Schistosoma mansoni | SmCL2-like peptidase (C01 family) | 0.0218 | 0.2757 | 0.2757 |
Brugia malayi | Cathepsin L-like precursor | 0.0423 | 1 | 1 |
Brugia malayi | Cathepsin L-like precursor | 0.0423 | 1 | 1 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.0423 | 1 | 1 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.0423 | 1 | 1 |
Plasmodium vivax | unspecified product | 0.0218 | 0.2757 | 0.2757 |
Plasmodium vivax | vivapain-2 | 0.0423 | 1 | 1 |
Leishmania major | cathepsin L-like protease | 0.0423 | 1 | 0.5 |
Echinococcus multilocularis | cathepsin L cysteine protease | 0.0423 | 1 | 1 |
Trypanosoma cruzi | cysteine protease, putative | 0.0218 | 0.2757 | 0.2757 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L or K-like cysteine peptidase | 0.0423 | 1 | 1 |
Echinococcus multilocularis | cathepsin l cysteine peptidase | 0.0423 | 1 | 1 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0423 | 1 | 1 |
Onchocerca volvulus | 0.0423 | 1 | 1 | |
Schistosoma mansoni | cathepsin F (C01 family) | 0.0423 | 1 | 1 |
Trypanosoma cruzi | cysteine peptidase (N-terminal), putative | 0.0218 | 0.2757 | 0.2757 |
Echinococcus granulosus | cathepsin l cysteine peptidase | 0.0423 | 1 | 1 |
Brugia malayi | cathepsin L-like precursor | 0.0283 | 0.5061 | 0.5061 |
Leishmania major | cathepsin L-like protease | 0.0423 | 1 | 0.5 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0423 | 1 | 1 |
Onchocerca volvulus | 0.0423 | 1 | 1 | |
Brugia malayi | Papain family cysteine protease containing protein | 0.0423 | 1 | 1 |
Entamoeba histolytica | cysteine proteinase, putative | 0.0423 | 1 | 1 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0423 | 1 | 1 |
Brugia malayi | Cathepsin L-like precursor | 0.0283 | 0.5061 | 0.5061 |
Loa Loa (eye worm) | hypothetical protein | 0.0283 | 0.5061 | 0.5061 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0283 | 0.5061 | 0.3182 |
Trypanosoma cruzi | cysteine peptidase, putative | 0.0423 | 1 | 1 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.0423 | 1 | 1 |
Trypanosoma cruzi | cysteine proteinase, putative | 0.0218 | 0.2757 | 0.2757 |
Leishmania major | cathepsin L-like protease | 0.0423 | 1 | 0.5 |
Leishmania major | cathepsin L-like protease | 0.0423 | 1 | 0.5 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0423 | 1 | 1 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0423 | 1 | 1 |
Echinococcus multilocularis | cathepsin L cysteine protease | 0.0423 | 1 | 1 |
Toxoplasma gondii | cathepsin CPL | 0.0423 | 1 | 0.5 |
Brugia malayi | Cathepsin L-like precursor | 0.0423 | 1 | 1 |
Echinococcus multilocularis | cysteine protease | 0.0423 | 1 | 1 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0423 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0423 | 1 | 1 |
Entamoeba histolytica | cysteine protease, putative | 0.0423 | 1 | 1 |
Schistosoma mansoni | SmCL2-like peptidase (C01 family) | 0.0218 | 0.2757 | 0.2757 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0423 | 1 | 1 |
Onchocerca volvulus | Cathepsin L homolog | 0.0423 | 1 | 1 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0423 | 1 | 1 |
Plasmodium vivax | vivapain-1 | 0.0218 | 0.2757 | 0.2757 |
Entamoeba histolytica | cysteine proteinase, putative | 0.0423 | 1 | 1 |
Trypanosoma cruzi | cysteine peptidase, putative | 0.0423 | 1 | 1 |
Onchocerca volvulus | 0.0423 | 1 | 1 | |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0423 | 1 | 1 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0423 | 1 | 1 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0423 | 1 | 1 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0423 | 1 | 1 |
Echinococcus multilocularis | cathepsin l cysteine peptidase | 0.0423 | 1 | 1 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0423 | 1 | 1 |
Leishmania major | cathepsin L-like protease | 0.0423 | 1 | 0.5 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0423 | 1 | 1 |
Loa Loa (eye worm) | cysteine protease | 0.0423 | 1 | 1 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0423 | 1 | 1 |
Echinococcus granulosus | cathepsin l1 | 0.0423 | 1 | 1 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0423 | 1 | 1 |
Leishmania major | cathepsin L-like protease | 0.0423 | 1 | 0.5 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0423 | 1 | 1 |
Plasmodium falciparum | cysteine proteinase falcipain 2a | 0.0423 | 1 | 1 |
Brugia malayi | Papain family cysteine protease containing protein | 0.0218 | 0.2757 | 0.2757 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.0423 | 1 | 1 |
Onchocerca volvulus | 0.0423 | 1 | 1 | |
Echinococcus granulosus | cathepsin l1 | 0.0283 | 0.5061 | 0.3182 |
Onchocerca volvulus | 0.0423 | 1 | 1 | |
Brugia malayi | Cathepsin L-like precursor | 0.0283 | 0.5061 | 0.5061 |
Leishmania major | cathepsin L-like protease | 0.0423 | 1 | 0.5 |
Trypanosoma cruzi | cysteine peptidase, putative | 0.0423 | 1 | 1 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0423 | 1 | 1 |
Plasmodium falciparum | cysteine proteinase falcipain 2b | 0.0423 | 1 | 1 |
Loa Loa (eye worm) | fibroinase | 0.0423 | 1 | 1 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.0423 | 1 | 1 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0423 | 1 | 1 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0423 | 1 | 1 |
Trypanosoma cruzi | cysteine peptidase, clan CA, family C1, cathepsin L-like, putative | 0.0283 | 0.5061 | 0.5061 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0423 | 1 | 1 |
Brugia malayi | Papain family cysteine protease containing protein | 0.0218 | 0.2757 | 0.2757 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0283 | 0.5061 | 0.3182 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0423 | 1 | 1 |
Loa Loa (eye worm) | ctsf protein | 0.0423 | 1 | 1 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.0423 | 1 | 1 |
Loa Loa (eye worm) | papain family cysteine protease containing protein | 0.0423 | 1 | 1 |
Brugia malayi | Cathepsin L-like precursor | 0.0423 | 1 | 1 |
Echinococcus multilocularis | cysteine protease | 0.0423 | 1 | 1 |
Trypanosoma cruzi | cruzipain precursor, putative | 0.0423 | 1 | 1 |
Trypanosoma cruzi | cysteine peptidase, putative | 0.0423 | 1 | 1 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.0423 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0283 | 0.5061 | 0.5061 |
Trypanosoma cruzi | cysteine peptidase, putative | 0.0218 | 0.2757 | 0.2757 |
Brugia malayi | Cathepsin L-like precursor | 0.0423 | 1 | 1 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.0423 | 1 | 1 |
Brugia malayi | Cathepsin L-like cysteine proteinase | 0.0283 | 0.5061 | 0.5061 |
Onchocerca volvulus | 0.0423 | 1 | 1 | |
Loa Loa (eye worm) | Papain cysteine protease/cathepsin propeptide inhibitor-containing protein | 0.0423 | 1 | 1 |
Trypanosoma cruzi | cysteine proteinase, putative | 0.0218 | 0.2757 | 0.2757 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0423 | 1 | 1 |
Leishmania major | cathepsin L-like protease | 0.0423 | 1 | 0.5 |
Onchocerca volvulus | Cathepsin L homolog | 0.0423 | 1 | 1 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.
1 literature reference was collected for this gene.