Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Brugia malayi | Dopamine receptor protein 1 | 0.0029 | 0.0168 | 0.0484 |
Trichomonas vaginalis | AGC family protein kinase | 0.0094 | 0.0845 | 1 |
Schistosoma mansoni | atypical protein kinase C | 0.0276 | 0.2722 | 0.7968 |
Echinococcus multilocularis | ribosomal protein S6 kinase alpha 3 | 0.0089 | 0.0794 | 0.0776 |
Trichomonas vaginalis | AGC family protein kinase | 0.0089 | 0.0794 | 0.4053 |
Loa Loa (eye worm) | hypothetical protein | 0.0029 | 0.0168 | 0.0391 |
Echinococcus multilocularis | neuropeptide FF receptor 2 | 0.0029 | 0.0168 | 0.0149 |
Brugia malayi | Tachykinin-like peptides receptor 99D | 0.0029 | 0.0168 | 0.0484 |
Brugia malayi | hypothetical protein | 0.0029 | 0.0168 | 0.0484 |
Loa Loa (eye worm) | hypothetical protein | 0.0029 | 0.0168 | 0.0391 |
Onchocerca volvulus | 0.0232 | 0.2268 | 0.6684 | |
Loa Loa (eye worm) | RhoGAP domain-containing protein | 0.008 | 0.0701 | 0.1652 |
Schistosoma mansoni | rac gtpase activating protein | 0.008 | 0.0701 | 0.2053 |
Schistosoma mansoni | serine/threonine protein kinase | 0.0089 | 0.0794 | 0.2323 |
Loa Loa (eye worm) | hypothetical protein | 0.0029 | 0.0168 | 0.0391 |
Brugia malayi | G-protein-linked acetylcholine receptor protein 2, putative | 0.0029 | 0.0168 | 0.0484 |
Brugia malayi | hypothetical protein | 0.0029 | 0.0168 | 0.0484 |
Brugia malayi | ORL1-like opioid receptor | 0.0029 | 0.0168 | 0.0484 |
Echinococcus multilocularis | rhodopsin orphan GPCR | 0.0029 | 0.0168 | 0.0149 |
Loa Loa (eye worm) | hypothetical protein | 0.0029 | 0.0168 | 0.0391 |
Echinococcus multilocularis | RNA directed DNA polymerase | 0.0143 | 0.1346 | 0.1329 |
Schistosoma mansoni | biogenic amine receptor | 0.0029 | 0.0168 | 0.0492 |
Echinococcus granulosus | G protein coupled receptor 139 | 0.0029 | 0.0168 | 0.0438 |
Loa Loa (eye worm) | hypothetical protein | 0.0018 | 0.0057 | 0.0128 |
Echinococcus granulosus | rhodopsin orphan GPCR | 0.0029 | 0.0168 | 0.0438 |
Brugia malayi | protein kinase C3,putative | 0.0183 | 0.1762 | 0.5153 |
Schistosoma mansoni | hypothetical protein | 0.0029 | 0.0168 | 0.0492 |
Schistosoma mansoni | peptide (FMRFamide/somatostatin)-like receptor | 0.0029 | 0.0168 | 0.0492 |
Entamoeba histolytica | protein kinase, putative | 0.0094 | 0.0845 | 0.1468 |
Echinococcus multilocularis | G protein coupled receptor 139 | 0.0029 | 0.0168 | 0.0149 |
Schistosoma mansoni | hypothetical protein | 0.0029 | 0.0168 | 0.0492 |
Loa Loa (eye worm) | hypothetical protein | 0.0029 | 0.0168 | 0.0391 |
Trypanosoma brucei | rac serine-threonine kinase, putative | 0.0094 | 0.0845 | 0.5 |
Echinococcus multilocularis | sex peptide receptor | 0.0029 | 0.0168 | 0.0149 |
Schistosoma mansoni | diacylglycerol kinase theta | 0.008 | 0.0701 | 0.2053 |
Echinococcus multilocularis | neuropeptide Y receptor | 0.0029 | 0.0168 | 0.0149 |
Loa Loa (eye worm) | hypothetical protein | 0.0029 | 0.0168 | 0.0391 |
Loa Loa (eye worm) | hypothetical protein | 0.008 | 0.0701 | 0.1652 |
Schistosoma mansoni | serine/threonine protein kinase | 0.0084 | 0.0736 | 0.2155 |
Brugia malayi | Variant SH3 domain containing protein | 0.008 | 0.0701 | 0.2046 |
Onchocerca volvulus | 0.0227 | 0.2217 | 0.6522 | |
Trichomonas vaginalis | AGC family protein kinase | 0.0094 | 0.0845 | 1 |
Schistosoma mansoni | neuropeptide receptor | 0.0029 | 0.0168 | 0.0492 |
Echinococcus multilocularis | serine:threonine protein kinase N2 | 0.0256 | 0.2511 | 0.2497 |
Echinococcus multilocularis | peptide (allatostatin:somatostatin) | 0.0029 | 0.0168 | 0.0149 |
Schistosoma mansoni | chimerin-related rho-gtpase-activating protein | 0.008 | 0.0701 | 0.2053 |
Echinococcus multilocularis | rhodopsin orphan GPCR | 0.0029 | 0.0168 | 0.0149 |
Brugia malayi | diacylglycerol kinase | 0.008 | 0.0701 | 0.2046 |
Entamoeba histolytica | protein kinase, putative | 0.0094 | 0.0845 | 0.1468 |
Echinococcus granulosus | myotubularin protein 13 | 0.0085 | 0.0752 | 0.2158 |
Brugia malayi | hypothetical protein | 0.0029 | 0.0168 | 0.0484 |
Echinococcus multilocularis | N chimaerin | 0.008 | 0.0701 | 0.0683 |
Echinococcus granulosus | Rac GTPase activating protein 1 | 0.008 | 0.0701 | 0.2008 |
Echinococcus granulosus | somatostatin receptor | 0.0029 | 0.0168 | 0.0438 |
Echinococcus granulosus | twitchin | 0.0017 | 0.0054 | 0.0102 |
Brugia malayi | hypothetical protein | 0.0029 | 0.0168 | 0.0484 |
Schistosoma mansoni | peptide (FMRFamide/neurokinin-3)-like receptor | 0.0029 | 0.0168 | 0.0492 |
Echinococcus granulosus | tm gpcr rhodopsin | 0.0029 | 0.0168 | 0.0438 |
Echinococcus multilocularis | tm gpcr rhodopsin gpcr rhodopsin superfamily | 0.0029 | 0.0168 | 0.0149 |
Schistosoma mansoni | biogenic amine (5HT) receptor | 0.0029 | 0.0168 | 0.0492 |
Loa Loa (eye worm) | hypothetical protein | 0.0029 | 0.0168 | 0.0391 |
Brugia malayi | Unidentified vitellogenin-linked transcript protein 6, putative | 0.0029 | 0.0168 | 0.0484 |
Echinococcus granulosus | tm gpcr rhodopsin | 0.0029 | 0.0168 | 0.0438 |
Brugia malayi | Serotonin receptor | 0.0029 | 0.0168 | 0.0484 |
Loa Loa (eye worm) | hypothetical protein | 0.0029 | 0.0168 | 0.0391 |
Loa Loa (eye worm) | hypothetical protein | 0.0029 | 0.0168 | 0.0391 |
Loa Loa (eye worm) | hypothetical protein | 0.0029 | 0.0168 | 0.0391 |
Schistosoma mansoni | rhodopsin-like orphan GPCR | 0.0029 | 0.0168 | 0.0492 |
Echinococcus granulosus | ribosomal protein s6 kinase beta 1 | 0.0089 | 0.0794 | 0.2279 |
Echinococcus multilocularis | g protein coupled receptor | 0.0029 | 0.0168 | 0.0149 |
Loa Loa (eye worm) | hypothetical protein | 0.0029 | 0.0168 | 0.0391 |
Brugia malayi | larval opioid receptor | 0.0029 | 0.0168 | 0.0484 |
Loa Loa (eye worm) | hypothetical protein | 0.008 | 0.0701 | 0.1652 |
Echinococcus multilocularis | myotubularin protein 13 | 0.0085 | 0.0752 | 0.0735 |
Schistosoma mansoni | rhodopsin-like orphan GPCR | 0.0029 | 0.0168 | 0.0492 |
Brugia malayi | AKH receptor | 0.0029 | 0.0168 | 0.0484 |
Echinococcus multilocularis | protein kinase c epsilon type | 0.0344 | 0.3417 | 0.3404 |
Loa Loa (eye worm) | AGC/PKC/ETA protein kinase | 0.0344 | 0.3417 | 0.8078 |
Brugia malayi | hypothetical protein | 0.0029 | 0.0168 | 0.0484 |
Schistosoma mansoni | rhodopsin-like orphan GPCR | 0.0029 | 0.0168 | 0.0492 |
Echinococcus granulosus | neuropeptide receptor | 0.0029 | 0.0168 | 0.0438 |
Schistosoma mansoni | alpha-1 adrenergic receptor | 0.0029 | 0.0168 | 0.0492 |
Loa Loa (eye worm) | hypothetical protein | 0.0029 | 0.0168 | 0.0391 |
Loa Loa (eye worm) | G-protein-linked acetylcholine receptor protein 2 | 0.0029 | 0.0168 | 0.0391 |
Loa Loa (eye worm) | hypothetical protein | 0.0029 | 0.0168 | 0.0391 |
Brugia malayi | hypothetical protein | 0.0029 | 0.0168 | 0.0484 |
Schistosoma mansoni | amine GPCR | 0.0029 | 0.0168 | 0.0492 |
Echinococcus multilocularis | G protein coupled 5 hydroxytryptamine receptor | 0.0029 | 0.0168 | 0.0149 |
Brugia malayi | p70 ribosomal S6 kinase beta | 0.0089 | 0.0794 | 0.2316 |
Echinococcus multilocularis | rhodopsin orphan GPCR | 0.0029 | 0.0168 | 0.0149 |
Brugia malayi | gonadotropin-releasing hormone receptor 2 | 0.0029 | 0.0168 | 0.0484 |
Trichomonas vaginalis | AGC family protein kinase | 0.0094 | 0.0845 | 1 |
Schistosoma mansoni | histamine h1 receptor | 0.0029 | 0.0168 | 0.0492 |
Trichomonas vaginalis | AGC family protein kinase | 0.0094 | 0.0845 | 1 |
Brugia malayi | G protein-coupled receptor | 0.0029 | 0.0168 | 0.0484 |
Schistosoma mansoni | biogenic amine (5HT) receptor | 0.0029 | 0.0168 | 0.0492 |
Echinococcus multilocularis | telomerase reverse transcriptase subunit | 0.0143 | 0.1346 | 0.1329 |
Echinococcus multilocularis | neuropeptide receptor A26 | 0.0029 | 0.0168 | 0.0149 |
Brugia malayi | Protein kinase c protein 2 | 0.0234 | 0.2286 | 0.6689 |
Loa Loa (eye worm) | TYRA-2 protein | 0.0029 | 0.0168 | 0.0391 |
Echinococcus multilocularis | unc 13 (munc13) | 0.0088 | 0.0779 | 0.0762 |
Schistosoma mansoni | growth hormone secretagogue receptor | 0.0029 | 0.0168 | 0.0492 |
Echinococcus granulosus | Protein kinase C brain isozyme | 0.032 | 0.3171 | 0.9278 |
Loa Loa (eye worm) | gonadotropin-releasing hormone receptor 2 | 0.0029 | 0.0168 | 0.0391 |
Brugia malayi | hypothetical protein | 0.0029 | 0.0168 | 0.0484 |
Echinococcus granulosus | orexin receptor type 2 | 0.0029 | 0.0168 | 0.0438 |
Loa Loa (eye worm) | hypothetical protein | 0.0029 | 0.0168 | 0.0391 |
Loa Loa (eye worm) | hypothetical protein | 0.0029 | 0.0168 | 0.0391 |
Echinococcus granulosus | protein kinase c eta type | 0.008 | 0.0701 | 0.2008 |
Echinococcus granulosus | guanine nucleotide exchange factor VAV2 | 0.008 | 0.0701 | 0.2008 |
Loa Loa (eye worm) | hypothetical protein | 0.008 | 0.0701 | 0.1652 |
Echinococcus multilocularis | serine:threonine protein kinase N2 | 0.0089 | 0.0794 | 0.0776 |
Schistosoma mansoni | amine GPCR | 0.0029 | 0.0168 | 0.0492 |
Loa Loa (eye worm) | hypothetical protein | 0.0029 | 0.0168 | 0.0391 |
Trichomonas vaginalis | AGC family protein kinase | 0.0094 | 0.0845 | 1 |
Brugia malayi | neuropeptide F receptor | 0.0029 | 0.0168 | 0.0484 |
Echinococcus multilocularis | neuropeptides capa receptor | 0.0029 | 0.0168 | 0.0149 |
Schistosoma mansoni | hypothetical protein | 0.0029 | 0.0168 | 0.0492 |
Loa Loa (eye worm) | hypothetical protein | 0.0143 | 0.1346 | 0.3178 |
Echinococcus multilocularis | rhodopsin orphan GPCR | 0.0029 | 0.0168 | 0.0149 |
Loa Loa (eye worm) | hypothetical protein | 0.0223 | 0.2174 | 0.5136 |
Brugia malayi | diacylglycerol kinase | 0.008 | 0.0701 | 0.2046 |
Echinococcus multilocularis | rhodopsin orphan GPCR | 0.0029 | 0.0168 | 0.0149 |
Schistosoma mansoni | histamine-responsive GPCR (AAF21638) | 0.0029 | 0.0168 | 0.0492 |
Brugia malayi | hypothetical protein | 0.0029 | 0.0168 | 0.0484 |
Loa Loa (eye worm) | hypothetical protein | 0.0029 | 0.0168 | 0.0391 |
Brugia malayi | RhoGAP domain containing protein | 0.008 | 0.0701 | 0.2046 |
Echinococcus granulosus | tm gpcr rhodopsin | 0.0029 | 0.0168 | 0.0438 |
Schistosoma mansoni | biogenic amine receptor | 0.0029 | 0.0168 | 0.0492 |
Echinococcus granulosus | neuropeptide s receptor | 0.0029 | 0.0168 | 0.0438 |
Echinococcus multilocularis | serine threonine protein kinase | 0.024 | 0.2344 | 0.2329 |
Echinococcus granulosus | neuropeptides capa receptor | 0.0029 | 0.0168 | 0.0438 |
Echinococcus granulosus | tachykinin peptides receptor 99D | 0.0029 | 0.0168 | 0.0438 |
Loa Loa (eye worm) | unidentified vitellogenin-linked transcript protein 6 | 0.0029 | 0.0168 | 0.0391 |
Loa Loa (eye worm) | hypothetical protein | 0.0029 | 0.0168 | 0.0391 |
Echinococcus granulosus | neuropeptide FF receptor 2 | 0.0029 | 0.0168 | 0.0438 |
Loa Loa (eye worm) | hypothetical protein | 0.0029 | 0.0168 | 0.0391 |
Loa Loa (eye worm) | hypothetical protein | 0.0029 | 0.0168 | 0.0391 |
Echinococcus multilocularis | neuropeptide receptor | 0.0029 | 0.0168 | 0.0149 |
Echinococcus granulosus | C2 calcium dependent membrane targeting | 0.0088 | 0.0779 | 0.2238 |
Loa Loa (eye worm) | 5-hydroxytryptamine 2C receptor | 0.0029 | 0.0168 | 0.0391 |
Trichomonas vaginalis | AGC family protein kinase | 0.0094 | 0.0845 | 1 |
Echinococcus granulosus | neurotracting:lsamp:neurotrimin:obcam | 0.0015 | 0.0027 | 0.0024 |
Schistosoma mansoni | serine/threonine protein kinase | 0.0086 | 0.076 | 0.2225 |
Echinococcus multilocularis | G-protein coupled receptor, putative | 0.0029 | 0.0168 | 0.0149 |
Loa Loa (eye worm) | hypothetical protein | 0.0029 | 0.0168 | 0.0391 |
Brugia malayi | putative neuropeptide receptor | 0.0029 | 0.0168 | 0.0484 |
Echinococcus granulosus | neuropeptide receptor | 0.0029 | 0.0168 | 0.0438 |
Loa Loa (eye worm) | hypothetical protein | 0.0232 | 0.2268 | 0.5359 |
Echinococcus multilocularis | Diacylglycerol kinase theta | 0.008 | 0.0701 | 0.0683 |
Echinococcus granulosus | rhodopsin orphan GPCR | 0.0029 | 0.0168 | 0.0438 |
Echinococcus granulosus | neuropeptide receptor A26 | 0.0029 | 0.0168 | 0.0438 |
Echinococcus multilocularis | C2 calcium dependent membrane targeting | 0.0088 | 0.0779 | 0.0762 |
Loa Loa (eye worm) | CAMK/PKD protein kinase | 0.015 | 0.1424 | 0.3362 |
Brugia malayi | Protein kinase domain containing protein | 0.0089 | 0.0794 | 0.2316 |
Echinococcus granulosus | rhodopsin orphan GPCR | 0.0029 | 0.0168 | 0.0438 |
Trichomonas vaginalis | AGC family protein kinase | 0.0089 | 0.0794 | 0.4053 |
Loa Loa (eye worm) | hypothetical protein | 0.0029 | 0.0168 | 0.0391 |
Entamoeba histolytica | protein kinase, putative | 0.0089 | 0.0794 | 0.0944 |
Schistosoma mansoni | neuropeptide F-like receptor | 0.0029 | 0.0168 | 0.0492 |
Loa Loa (eye worm) | raf kinase | 0.008 | 0.0701 | 0.1652 |
Loa Loa (eye worm) | hypothetical protein | 0.0423 | 0.4229 | 1 |
Echinococcus multilocularis | guanine nucleotide exchange factor VAV2 | 0.008 | 0.0701 | 0.0683 |
Loa Loa (eye worm) | hypothetical protein | 0.0147 | 0.1389 | 0.328 |
Echinococcus multilocularis | dro:myosuppressin receptor | 0.0029 | 0.0168 | 0.0149 |
Loa Loa (eye worm) | TK/KIN16 protein kinase | 0.0187 | 0.1804 | 0.4261 |
Brugia malayi | Ras association domain family 1 isoform A | 0.008 | 0.0701 | 0.2046 |
Schistosoma mansoni | protein kinase C | 0.0088 | 0.0779 | 0.2281 |
Schistosoma mansoni | diacylglycerol kinase theta | 0.008 | 0.0701 | 0.2053 |
Echinococcus multilocularis | g protein coupled receptor | 0.0029 | 0.0168 | 0.0149 |
Schistosoma mansoni | myosin xvIII | 0.0029 | 0.0168 | 0.0492 |
Echinococcus multilocularis | serotonin receptor | 0.0029 | 0.0168 | 0.0149 |
Loa Loa (eye worm) | hypothetical protein | 0.0015 | 0.0024 | 0.0049 |
Echinococcus granulosus | serotonin receptor | 0.0029 | 0.0168 | 0.0438 |
Echinococcus multilocularis | serine:threonine protein kinase MRCK beta | 0.0084 | 0.0736 | 0.0718 |
Brugia malayi | Serotonin/octopamine receptor family protein 7 | 0.0029 | 0.0168 | 0.0484 |
Loa Loa (eye worm) | AGC/PKN protein kinase | 0.0089 | 0.0794 | 0.1871 |
Echinococcus multilocularis | growth hormone secretagogue receptor type 1 | 0.0029 | 0.0168 | 0.0149 |
Echinococcus granulosus | alpha 1A adrenergic receptor | 0.0029 | 0.0168 | 0.0438 |
Loa Loa (eye worm) | hypothetical protein | 0.0029 | 0.0168 | 0.0391 |
Brugia malayi | Serotonin receptor | 0.0029 | 0.0168 | 0.0484 |
Brugia malayi | Dopamine receptor protein 2 | 0.0029 | 0.0168 | 0.0484 |
Schistosoma mansoni | opsin-like receptor | 0.0029 | 0.0168 | 0.0492 |
Echinococcus multilocularis | pyroglutamylated rfamide peptide receptor | 0.0029 | 0.0168 | 0.0149 |
Schistosoma mansoni | nephrin | 0.0014 | 0.0019 | 0.0056 |
Echinococcus multilocularis | allatostatin A receptor | 0.0029 | 0.0168 | 0.0149 |
Schistosoma mansoni | serine/threonine protein kinase | 0.0084 | 0.0736 | 0.2155 |
Schistosoma mansoni | neuropeptide f receptor 76f | 0.0029 | 0.0168 | 0.0492 |
Loa Loa (eye worm) | hypothetical protein | 0.0227 | 0.2217 | 0.5238 |
Echinococcus granulosus | g protein coupled receptor | 0.0029 | 0.0168 | 0.0438 |
Echinococcus granulosus | Serine/threonine-protein kinase Genghis Khan | 0.0084 | 0.0736 | 0.211 |
Brugia malayi | Protein kinase domain containing protein | 0.0089 | 0.0794 | 0.2316 |
Echinococcus granulosus | hypothetical protein | 0.0029 | 0.0168 | 0.0438 |
Echinococcus granulosus | g protein linked acetylcholine receptor gar 2a | 0.0029 | 0.0168 | 0.0438 |
Echinococcus multilocularis | serotonin receptor | 0.0029 | 0.0168 | 0.0149 |
Loa Loa (eye worm) | hypothetical protein | 0.0029 | 0.0168 | 0.0391 |
Echinococcus multilocularis | g protein linked acetylcholine receptor gar 2a | 0.0029 | 0.0168 | 0.0149 |
Schistosoma mansoni | rhodopsin-like orphan GPCR | 0.0029 | 0.0168 | 0.0492 |
Schistosoma mansoni | unc-13 (munc13) | 0.0088 | 0.0779 | 0.2281 |
Echinococcus granulosus | rhodopsin orphan GPCR | 0.0029 | 0.0168 | 0.0438 |
Trichomonas vaginalis | AGC family protein kinase | 0.0094 | 0.0845 | 1 |
Schistosoma mansoni | neuropeptide receptor | 0.0029 | 0.0168 | 0.0492 |
Schistosoma mansoni | protein kinase C mu | 0.0231 | 0.2251 | 0.6589 |
Brugia malayi | Protein kinase domain containing protein | 0.0084 | 0.0736 | 0.2147 |
Echinococcus granulosus | RNA directed DNA polymerase | 0.0143 | 0.1346 | 0.3905 |
Echinococcus multilocularis | tachykinin peptides receptor 99D | 0.0029 | 0.0168 | 0.0149 |
Toxoplasma gondii | AGC kinase | 0.0089 | 0.0794 | 1 |
Brugia malayi | Hr1 repeat family protein | 0.0089 | 0.0794 | 0.2316 |
Schistosoma mansoni | rhodopsin-like orphan GPCR | 0.0029 | 0.0168 | 0.0492 |
Loa Loa (eye worm) | hypothetical protein | 0.0029 | 0.0168 | 0.0391 |
Brugia malayi | Protein kinase domain containing protein | 0.0094 | 0.0845 | 0.2465 |
Schistosoma mansoni | amine GPCR | 0.0029 | 0.0168 | 0.0492 |
Echinococcus granulosus | peptide allatostatin:somatostatin | 0.0029 | 0.0168 | 0.0438 |
Echinococcus multilocularis | orexin receptor type 2 | 0.0029 | 0.0168 | 0.0149 |
Onchocerca volvulus | Tyrosine kinase homolog | 0.0175 | 0.168 | 0.4813 |
Schistosoma mansoni | biogenic amine (dopamine) receptor | 0.0029 | 0.0168 | 0.0492 |
Entamoeba histolytica | protein kinase, putative | 0.0089 | 0.0794 | 0.0944 |
Loa Loa (eye worm) | G-protein coupled receptor | 0.0029 | 0.0168 | 0.0391 |
Onchocerca volvulus | 0.0167 | 0.1591 | 0.4532 | |
Echinococcus multilocularis | thyrotropin releasing hormone receptor | 0.0029 | 0.0168 | 0.0149 |
Brugia malayi | sulfakinin receptor protein | 0.0029 | 0.0168 | 0.0484 |
Echinococcus multilocularis | tm gpcr rhodopsin gpcr rhodopsin superfamily | 0.0029 | 0.0168 | 0.0149 |
Loa Loa (eye worm) | hypothetical protein | 0.0029 | 0.0168 | 0.0391 |
Loa Loa (eye worm) | hypothetical protein | 0.0333 | 0.3309 | 0.7824 |
Schistosoma mansoni | amine GPCR | 0.0029 | 0.0168 | 0.0492 |
Loa Loa (eye worm) | hypothetical protein | 0.0029 | 0.0168 | 0.0391 |
Echinococcus granulosus | g protein coupled receptor | 0.0029 | 0.0168 | 0.0438 |
Echinococcus multilocularis | 7TM GPCR, rhodopsin | 0.0029 | 0.0168 | 0.0149 |
Echinococcus granulosus | rhodopsin orphan GPCR | 0.0029 | 0.0168 | 0.0438 |
Echinococcus granulosus | g protein linked acetylcholine receptor gar 2a | 0.0029 | 0.0168 | 0.0438 |
Schistosoma mansoni | serine/threonine protein kinase | 0.0344 | 0.3417 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0029 | 0.0168 | 0.0391 |
Schistosoma mansoni | biogenic amine receptor | 0.0029 | 0.0168 | 0.0492 |
Loa Loa (eye worm) | RasGEF domain-containing protein | 0.008 | 0.0701 | 0.1652 |
Loa Loa (eye worm) | AGC/AKT protein kinase | 0.0094 | 0.0845 | 0.1991 |
Loa Loa (eye worm) | hypothetical protein | 0.0029 | 0.0168 | 0.0391 |
Echinococcus granulosus | serine:threonine protein kinase N2 | 0.017 | 0.1626 | 0.473 |
Echinococcus granulosus | pyroglutamylated rfamide peptide receptor | 0.0029 | 0.0168 | 0.0438 |
Brugia malayi | G-protein coupled receptor | 0.0029 | 0.0168 | 0.0484 |
Loa Loa (eye worm) | hypothetical protein | 0.008 | 0.0701 | 0.1652 |
Echinococcus multilocularis | Ribosomal protein S6 kinase beta 2 | 0.0089 | 0.0794 | 0.0776 |
Echinococcus multilocularis | Protein kinase C, brain isozyme | 0.032 | 0.3171 | 0.3158 |
Echinococcus granulosus | neuropeptide Y receptor | 0.0029 | 0.0168 | 0.0438 |
Loa Loa (eye worm) | hypothetical protein | 0.0029 | 0.0168 | 0.0391 |
Loa Loa (eye worm) | hypothetical protein | 0.0333 | 0.3309 | 0.7824 |
Schistosoma mansoni | serine/threonine protein kinase | 0.033 | 0.3275 | 0.9584 |
Schistosoma mansoni | opsin-like receptor | 0.0029 | 0.0168 | 0.0492 |
Loa Loa (eye worm) | hypothetical protein | 0.0333 | 0.3309 | 0.7824 |
Brugia malayi | protein kinase C II. | 0.0344 | 0.3417 | 1 |
Echinococcus multilocularis | intersectin 2 | 0.0017 | 0.0051 | 0.0032 |
Loa Loa (eye worm) | AGC/RSK/P70 protein kinase | 0.0089 | 0.0794 | 0.1871 |
Loa Loa (eye worm) | CAMK/PKD protein kinase | 0.0231 | 0.2251 | 0.5321 |
Schistosoma mansoni | serine/threonine protein kinase | 0.0089 | 0.0794 | 0.2323 |
Echinococcus multilocularis | neuropeptide s receptor | 0.0029 | 0.0168 | 0.0149 |
Loa Loa (eye worm) | hypothetical protein | 0.0029 | 0.0168 | 0.0391 |
Loa Loa (eye worm) | hypothetical protein | 0.0029 | 0.0168 | 0.0391 |
Echinococcus multilocularis | neuropeptide Y receptor | 0.0029 | 0.0168 | 0.0149 |
Loa Loa (eye worm) | hypothetical protein | 0.0015 | 0.0027 | 0.0058 |
Echinococcus multilocularis | tm gpcr rhodopsin gpcr rhodopsin superfamily | 0.0029 | 0.0168 | 0.0149 |
Schistosoma mansoni | thyrotropin-releasing hormone receptor | 0.0029 | 0.0168 | 0.0492 |
Echinococcus multilocularis | g protein coupled receptor | 0.0029 | 0.0168 | 0.0149 |
Entamoeba histolytica | PH domain containing protein kinase, putative | 0.0175 | 0.1677 | 1 |
Echinococcus multilocularis | protein kinase c iota type | 0.0269 | 0.2647 | 0.2633 |
Schistosoma mansoni | hypothetical protein | 0.0029 | 0.0168 | 0.0492 |
Schistosoma mansoni | peptide (FMRFamide/somatostatin)-like receptor | 0.0029 | 0.0168 | 0.0492 |
Echinococcus multilocularis | rhodopsin orphan GPCR | 0.0029 | 0.0168 | 0.0149 |
Schistosoma mansoni | rhogef and pleckstrin domain protein | 0.0015 | 0.0024 | 0.007 |
Schistosoma mansoni | serine/threonine protein kinase | 0.0089 | 0.0794 | 0.2323 |
Loa Loa (eye worm) | hypothetical protein | 0.0029 | 0.0168 | 0.0391 |
Brugia malayi | Phorbol esters/diacylglycerol binding domain | 0.0231 | 0.2251 | 0.6586 |
Echinococcus granulosus | Diacylglycerol kinase theta | 0.008 | 0.0701 | 0.2008 |
Loa Loa (eye worm) | follicle stimulating hormone receptor | 0.0029 | 0.0168 | 0.0391 |
Echinococcus granulosus | protein kinase C gamma type | 0.024 | 0.2344 | 0.6842 |
Echinococcus granulosus | intersectin 2 | 0.0017 | 0.0051 | 0.0093 |
Loa Loa (eye worm) | hypothetical protein | 0.0029 | 0.0168 | 0.0391 |
Echinococcus multilocularis | serine:threonine protein kinase 38 | 0.0089 | 0.0794 | 0.0776 |
Schistosoma mansoni | vav2 | 0.0085 | 0.0752 | 0.2202 |
Brugia malayi | G protein-coupled receptor F59B2.13 | 0.0029 | 0.0168 | 0.0484 |
Loa Loa (eye worm) | hypothetical protein | 0.0029 | 0.0168 | 0.0391 |
Loa Loa (eye worm) | hypothetical protein | 0.0085 | 0.0752 | 0.1773 |
Echinococcus granulosus | Ribosomal protein S6 kinase beta 2 | 0.0089 | 0.0794 | 0.2279 |
Brugia malayi | G-protein coupled receptor | 0.0029 | 0.0168 | 0.0484 |
Brugia malayi | Variant SH3 domain containing protein | 0.0013 | 0.0008 | 0.0013 |
Loa Loa (eye worm) | hypothetical protein | 0.0029 | 0.0168 | 0.0391 |
Echinococcus granulosus | fmrfamide receptor | 0.0029 | 0.0168 | 0.0438 |
Echinococcus multilocularis | protein kinase c eta type | 0.008 | 0.0701 | 0.0683 |
Echinococcus granulosus | protein kinase c iota type | 0.0269 | 0.2647 | 0.7734 |
Schistosoma mansoni | cell adhesion molecule | 0.0015 | 0.0027 | 0.008 |
Echinococcus multilocularis | g protein linked acetylcholine receptor gar 2a | 0.0029 | 0.0168 | 0.0149 |
Echinococcus granulosus | protein kinase c epsilon type | 0.0344 | 0.3417 | 1 |
Echinococcus granulosus | mitogen-activated protein kinase kinase kinase 9 | 0.034 | 0.3373 | 0.9873 |
Echinococcus granulosus | g protein coupled receptor | 0.0029 | 0.0168 | 0.0438 |
Schistosoma mansoni | rhodopsin-like orphan GPCR | 0.0029 | 0.0168 | 0.0492 |
Loa Loa (eye worm) | melatonin receptor type 1A | 0.0029 | 0.0168 | 0.0391 |
Brugia malayi | Melatonin receptor type 1A | 0.0029 | 0.0168 | 0.0484 |
Echinococcus multilocularis | rhodopsin orphan GPCR | 0.0029 | 0.0168 | 0.0149 |
Loa Loa (eye worm) | AGC/RSK/MSK protein kinase | 0.0089 | 0.0794 | 0.1871 |
Echinococcus granulosus | serine:threonine protein kinase N2 | 0.0089 | 0.0794 | 0.2279 |
Loa Loa (eye worm) | hypothetical protein | 0.0018 | 0.0057 | 0.0128 |
Echinococcus granulosus | unc 13 munc13 | 0.0088 | 0.0779 | 0.2238 |
Schistosoma mansoni | neuropeptide receptor | 0.0029 | 0.0168 | 0.0492 |
Echinococcus multilocularis | neuropeptide receptor | 0.0029 | 0.0168 | 0.0149 |
Schistosoma mansoni | peptide (allatostatin)-like receptor | 0.0029 | 0.0168 | 0.0492 |
Echinococcus granulosus | NDR protein kinase | 0.0089 | 0.0794 | 0.2279 |
Onchocerca volvulus | 0.0333 | 0.3309 | 1 | |
Loa Loa (eye worm) | TKL/MLK/MLK protein kinase | 0.0013 | 0.0008 | 0.001 |
Loa Loa (eye worm) | neuropeptide F receptor | 0.0029 | 0.0168 | 0.0391 |
Brugia malayi | RhoGAP domain containing protein | 0.008 | 0.0701 | 0.2046 |
Brugia malayi | neuropeptide F receptor | 0.0029 | 0.0168 | 0.0484 |
Echinococcus granulosus | growth hormone secretagogue receptor type 1 | 0.0029 | 0.0168 | 0.0438 |
Schistosoma mansoni | ancient conserved domain protein 2 (cyclin m2) | 0.0029 | 0.0168 | 0.0492 |
Loa Loa (eye worm) | AGC/PKC/IOTA protein kinase | 0.0191 | 0.1837 | 0.4341 |
Schistosoma mansoni | biogenic amine (dopamine) receptor | 0.0029 | 0.0168 | 0.0492 |
Schistosoma mansoni | amine GPCR | 0.0029 | 0.0168 | 0.0492 |
Echinococcus granulosus | N chimaerin | 0.008 | 0.0701 | 0.2008 |
Loa Loa (eye worm) | hypothetical protein | 0.0029 | 0.0168 | 0.0391 |
Brugia malayi | hypothetical protein | 0.0029 | 0.0168 | 0.0484 |
Brugia malayi | putative neuropeptide receptor NPR1 | 0.0029 | 0.0168 | 0.0484 |
Schistosoma mansoni | protein kinase C mu | 0.008 | 0.0701 | 0.2053 |
Echinococcus granulosus | 7tm_1 domain containing protein | 0.0029 | 0.0168 | 0.0438 |
Echinococcus granulosus | sex peptide receptor | 0.0029 | 0.0168 | 0.0438 |
Schistosoma mansoni | peptide (allatostatin/somatostatin)-like receptor | 0.0029 | 0.0168 | 0.0492 |
Echinococcus granulosus | rhodopsin orphan GPCR | 0.0029 | 0.0168 | 0.0438 |
Brugia malayi | C1-like domain containing protein | 0.0231 | 0.2251 | 0.6586 |
Schistosoma mansoni | hypothetical protein | 0.008 | 0.0701 | 0.2053 |
Loa Loa (eye worm) | G-protein coupled receptor | 0.0029 | 0.0168 | 0.0391 |
Schistosoma mansoni | opsin-like receptor | 0.0029 | 0.0168 | 0.0492 |
Brugia malayi | Variant SH3 domain containing protein | 0.0015 | 0.0024 | 0.0061 |
Brugia malayi | Dopamine receptor | 0.0029 | 0.0168 | 0.0484 |
Loa Loa (eye worm) | variant SH3 domain-containing protein | 0.008 | 0.0701 | 0.1652 |
Schistosoma mansoni | adenoreceptor | 0.0029 | 0.0168 | 0.0492 |
Trichomonas vaginalis | AGC family protein kinase | 0.0089 | 0.0794 | 0.4053 |
Loa Loa (eye worm) | AGC/RSK/RSK protein kinase | 0.0089 | 0.0794 | 0.1871 |
Loa Loa (eye worm) | hypothetical protein | 0.0029 | 0.0168 | 0.0391 |
Schistosoma mansoni | neuropeptide receptor | 0.0029 | 0.0168 | 0.0492 |
Loa Loa (eye worm) | hypothetical protein | 0.0029 | 0.0168 | 0.0391 |
Echinococcus granulosus | raf serine:threonine protein kinase | 0.0086 | 0.076 | 0.2181 |
Schistosoma mansoni | neuropeptide F-like receptor | 0.0029 | 0.0168 | 0.0492 |
Echinococcus multilocularis | biogenic amine (5HT) receptor | 0.0029 | 0.0168 | 0.0149 |
Echinococcus granulosus | rhodopsin orphan GPCR | 0.0029 | 0.0168 | 0.0438 |
Schistosoma mansoni | rhodopsin-like orphan GPCR | 0.0029 | 0.0168 | 0.0492 |
Loa Loa (eye worm) | hypothetical protein | 0.0414 | 0.4136 | 0.9782 |
Loa Loa (eye worm) | hypothetical protein | 0.0029 | 0.0168 | 0.0391 |
Loa Loa (eye worm) | hypothetical protein | 0.0147 | 0.1389 | 0.328 |
Echinococcus multilocularis | neuropeptides capa receptor | 0.0029 | 0.0168 | 0.0149 |
Loa Loa (eye worm) | hypothetical protein | 0.008 | 0.0701 | 0.1652 |
Echinococcus multilocularis | ribosomal protein s6 kinase beta 1 | 0.0089 | 0.0794 | 0.0776 |
Echinococcus granulosus | g-protein coupled receptor | 0.0029 | 0.0168 | 0.0438 |
Loa Loa (eye worm) | hypothetical protein | 0.0029 | 0.0168 | 0.0391 |
Schistosoma mansoni | tyrosine kinase | 0.0015 | 0.0031 | 0.0092 |
Schistosoma mansoni | biogenic amine (octopamine/dopamine) receptor | 0.0029 | 0.0168 | 0.0492 |
Echinococcus granulosus | G protein coupled 5 hydroxytryptamine receptor | 0.0029 | 0.0168 | 0.0438 |
Echinococcus granulosus | ribosomal protein S6 kinase alpha 3 | 0.0089 | 0.0794 | 0.2279 |
Onchocerca volvulus | 0.0088 | 0.0779 | 0.1946 | |
Echinococcus multilocularis | roundabout 2 | 0.0018 | 0.0057 | 0.0038 |
Brugia malayi | follicle stimulating hormone receptor | 0.0029 | 0.0168 | 0.0484 |
Loa Loa (eye worm) | AGC/PKC/ALPHA protein kinase | 0.0154 | 0.1459 | 0.3446 |
Echinococcus multilocularis | fmrfamide receptor | 0.0029 | 0.0168 | 0.0149 |
Loa Loa (eye worm) | hypothetical protein | 0.0029 | 0.0168 | 0.0391 |
Schistosoma mansoni | serine/threonine protein kinase | 0.032 | 0.3171 | 0.9282 |
Schistosoma mansoni | rhodopsin-like orphan GPCR | 0.0029 | 0.0168 | 0.0492 |
Loa Loa (eye worm) | hypothetical protein | 0.0029 | 0.0168 | 0.0391 |
Echinococcus multilocularis | rhodopsin orphan GPCR | 0.0029 | 0.0168 | 0.0149 |
Schistosoma mansoni | serine/threonine protein kinase | 0.032 | 0.3171 | 0.9282 |
Schistosoma mansoni | serine/threonine protein kinase | 0.0089 | 0.0794 | 0.2323 |
Brugia malayi | RE15519p | 0.0029 | 0.0168 | 0.0484 |
Schistosoma mansoni | biogenic amine (dopamine) receptor | 0.0029 | 0.0168 | 0.0492 |
Brugia malayi | GnHR receptor homolog | 0.0029 | 0.0168 | 0.0484 |
Loa Loa (eye worm) | hypothetical protein | 0.0029 | 0.0168 | 0.0391 |
Echinococcus granulosus | thyrotropin releasing hormone receptor | 0.0029 | 0.0168 | 0.0438 |
Schistosoma mansoni | unc-13 (munc13) | 0.0088 | 0.0779 | 0.2281 |
Loa Loa (eye worm) | hypothetical protein | 0.0088 | 0.0779 | 0.1837 |
Schistosoma mansoni | rhodopsin-like orphan GPCR | 0.0029 | 0.0168 | 0.0492 |
Echinococcus granulosus | allatostatin A receptor | 0.0029 | 0.0168 | 0.0438 |
Brugia malayi | Pleckstrin Homology Domain | 0.0085 | 0.0752 | 0.2195 |
Loa Loa (eye worm) | AGC/NDR protein kinase | 0.0089 | 0.0794 | 0.1871 |
Loa Loa (eye worm) | AGC/DMPK/GEK protein kinase | 0.0089 | 0.0794 | 0.1871 |
Echinococcus multilocularis | g-protein coupled receptor | 0.0029 | 0.0168 | 0.0149 |
Echinococcus granulosus | neuropeptides capa receptor | 0.0029 | 0.0168 | 0.0438 |
Echinococcus granulosus | neuropeptide Y receptor | 0.0029 | 0.0168 | 0.0438 |
Brugia malayi | Immunoglobulin I-set domain containing protein | 0.0187 | 0.1804 | 0.5275 |
Echinococcus granulosus | 7TM GPCR rhodopsin | 0.0029 | 0.0168 | 0.0438 |
Brugia malayi | hypothetical protein | 0.0029 | 0.0168 | 0.0484 |
Brugia malayi | RhoGEF domain containing protein | 0.008 | 0.0701 | 0.2046 |
Loa Loa (eye worm) | Ras association domain family 1 isoform A | 0.008 | 0.0701 | 0.1652 |
Echinococcus multilocularis | mitogen activated protein kinase kinase kinase | 0.034 | 0.3373 | 0.3361 |
Echinococcus multilocularis | fmrfamide receptor | 0.0029 | 0.0168 | 0.0149 |
Echinococcus granulosus | biogenic amine 5HT receptor | 0.0029 | 0.0168 | 0.0438 |
Trichomonas vaginalis | AGC family protein kinase | 0.0094 | 0.0845 | 1 |
Echinococcus granulosus | roundabout 2 | 0.0018 | 0.0057 | 0.0111 |
Echinococcus multilocularis | Rac GTPase activating protein 1 | 0.008 | 0.0701 | 0.0683 |
Echinococcus granulosus | dro:myosuppressin receptor | 0.0029 | 0.0168 | 0.0438 |
Loa Loa (eye worm) | neuropeptide F receptor | 0.0029 | 0.0168 | 0.0391 |
Echinococcus multilocularis | raf serine:threonine protein kinase | 0.0086 | 0.076 | 0.0742 |
Loa Loa (eye worm) | hypothetical protein | 0.008 | 0.0701 | 0.1652 |
Loa Loa (eye worm) | hypothetical protein | 0.0029 | 0.0168 | 0.0391 |
Echinococcus multilocularis | alpha 1A adrenergic receptor | 0.0029 | 0.0168 | 0.0149 |
Schistosoma mansoni | muscarinic acetylcholine (GAR) receptor | 0.0029 | 0.0168 | 0.0492 |
Schistosoma mansoni | serine/threonine kinase | 0.0089 | 0.0794 | 0.2323 |
Onchocerca volvulus | 0.0147 | 0.1389 | 0.3887 | |
Echinococcus granulosus | biogenic amine 5HT receptor | 0.0029 | 0.0168 | 0.0438 |
Brugia malayi | Dopamine receptor protein 1, putative (partial) | 0.0029 | 0.0168 | 0.0484 |
Echinococcus multilocularis | somatostatin receptor | 0.0029 | 0.0168 | 0.0149 |
Schistosoma mansoni | chimerin-related rho-gtpase-activating protein | 0.008 | 0.0701 | 0.2053 |
Activity type | Activity value | Assay description | Source | Reference |
---|---|---|---|---|
Activity (binding) | = 171 % | Enhancement of choline acetyltransferase activity in embryonic rat spinal cord at 300 nM | ChEMBL. | 17266195 |
Activity (binding) | = 171 % | Enhancement of choline acetyltransferase activity in embryonic rat spinal cord at 300 nM | ChEMBL. | 17266195 |
IC50 (binding) | = 22 nM | Inhibition of GST-MLK3 expressed in baculovirus | ChEMBL. | 17266195 |
IC50 (binding) | = 22 nM | Inhibition of GST-MLK3 expressed in baculovirus | ChEMBL. | 17266195 |
IC50 (binding) | = 46 nM | Inhibition of GST-MLK1 expressed in baculovirus | ChEMBL. | 17266195 |
IC50 (binding) | = 46 nM | Inhibition of GST-MLK1 expressed in baculovirus | ChEMBL. | 17266195 |
IC50 (binding) | = 205 nM | Inhibition of PKC | ChEMBL. | 17266195 |
IC50 (binding) | = 205 nM | Inhibition of PKC | ChEMBL. | 17266195 |
IC50 (functional) | = 274 nM | Inhibition of MKK4 phosphorylation in MLK1 transfected CHO cells after 1 hr | ChEMBL. | 17266195 |
IC50 (functional) | = 274 nM | Inhibition of MKK4 phosphorylation in MLK1 transfected CHO cells after 1 hr | ChEMBL. | 17266195 |
IC50 (binding) | > 300 nM | Inhibition of VEGFR2 | ChEMBL. | 17266195 |
IC50 (binding) | > 300 nM | Inhibition of VEGFR2 | ChEMBL. | 17266195 |
IC50 (binding) | > 1000 nM | Inhibition of DLK | ChEMBL. | 17266195 |
IC50 (binding) | > 1000 nM | Inhibition of TrkA | ChEMBL. | 17266195 |
IC50 (binding) | > 1000 nM | Inhibition of DLK | ChEMBL. | 17266195 |
IC50 (binding) | > 1000 nM | Inhibition of TrkA | ChEMBL. | 17266195 |
IC50 (binding) | = 3447 nM | Inhibition of GST-MLK2 | ChEMBL. | 17266195 |
IC50 (binding) | = 3447 nM | Inhibition of GST-MLK2 | ChEMBL. | 17266195 |
Inhibition (binding) | < 30 % | Inhibition of PDGFRbeta at 1 uM | ChEMBL. | 17266195 |
Inhibition (binding) | < 30 % | Inhibition of EGFR at 1 uM | ChEMBL. | 17266195 |
Inhibition (binding) | < 30 % | Inhibition of FGFR1 at 1 uM | ChEMBL. | 17266195 |
Inhibition (binding) | < 30 % | Inhibition of CDK1 at 1 uM | ChEMBL. | 17266195 |
Inhibition (binding) | < 30 % | Inhibition of CDK2 at 1 uM | ChEMBL. | 17266195 |
Inhibition (binding) | < 30 % | Inhibition of p38alpha at 1 uM | ChEMBL. | 17266195 |
Inhibition (binding) | < 30 % | Inhibition of TIE2 at 1 uM | ChEMBL. | 17266195 |
Inhibition (binding) | < 30 % | Inhibition of JNK1 at 1 uM | ChEMBL. | 17266195 |
Inhibition (binding) | < 30 % | Inhibition of IRKbeta at 1 uM | ChEMBL. | 17266195 |
Inhibition (binding) | < 30 % | Inhibition of PDGFRbeta at 1 uM | ChEMBL. | 17266195 |
Inhibition (binding) | < 30 % | Inhibition of EGFR at 1 uM | ChEMBL. | 17266195 |
Inhibition (binding) | < 30 % | Inhibition of FGFR1 at 1 uM | ChEMBL. | 17266195 |
Inhibition (binding) | < 30 % | Inhibition of CDK1 at 1 uM | ChEMBL. | 17266195 |
Inhibition (binding) | < 30 % | Inhibition of CDK2 at 1 uM | ChEMBL. | 17266195 |
Inhibition (binding) | < 30 % | Inhibition of p38alpha at 1 uM | ChEMBL. | 17266195 |
Inhibition (binding) | < 30 % | Inhibition of TIE2 at 1 uM | ChEMBL. | 17266195 |
Inhibition (binding) | < 30 % | Inhibition of JNK1 at 1 uM | ChEMBL. | 17266195 |
Inhibition (binding) | < 30 % | Inhibition of IRKbeta at 1 uM | ChEMBL. | 17266195 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.
1 literature reference was collected for this gene.