Detailed information for compound 411203

Basic information

Technical information
  • Name: Unnamed compound
  • MW: 1137.21 | Formula: C53H68N8O18S
  • H donors: 11 H acceptors: 16 LogP: 2.05 Rotable bonds: 20
    Rule of 5 violations (Lipinski): 4
  • SMILES: CC=C1NC(=O)[C@@H](NC(=O)[C@H](NC(=O)[C@H](NC(=O)[C@H](COS(=O)(=O)O)O)C)CCc2ccc(cc2)O)[C@@H](C)OC(=O)[C@@H](NC(=O)[C@H](N(C(=O)[C@H](N2C(=O)[C@H](NC1=O)CC[C@@H]2O)Cc1ccccc1)C)Cc1ccc(cc1)O)C(C)C
  • InChi: 1S/C53H68N8O18S/c1-7-36-46(67)57-38-23-24-42(65)61(51(38)72)40(26-32-11-9-8-10-12-32)52(73)60(6)39(25-33-15-20-35(63)21-16-33)48(69)58-43(28(2)3)53(74)79-30(5)44(50(71)55-36)59-47(68)37(22-17-31-13-18-34(62)19-14-31)56-45(66)29(4)54-49(70)41(64)27-78-80(75,76)77/h7-16,18-21,28-30,37-44,62-65H,17,22-27H2,1-6H3,(H,54,70)(H,55,71)(H,56,66)(H,57,67)(H,58,69)(H,59,68)(H,75,76,77)/b36-7-/t29-,30+,37-,38+,39+,40+,41+,42-,43+,44+/m1/s1
  • InChiKey: QVBXBGIPSMEBEL-JMBVFNMXSA-N  


Substructure search Similarity search

Network

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Synonyms

No synonyms found for this compound

Targets

Known targets for this compound

No curated genes were found associated with this compound

Predicted pathogen targets for this compound

By orthology
No druggable targets predicted by orthology data
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Brugia malayi Intermediate filament tail domain containing protein 0.0056 0.0142 0.0409
Echinococcus multilocularis diuretic hormone 44 receptor GPRdih2 0.0036 0.0067 0.0075
Echinococcus granulosus aryl hydrocarbon receptor 0.0042 0.009 0.0104
Loa Loa (eye worm) hypothetical protein 0.0058 0.0146 0.043
Schistosoma mansoni hyperpolarization activated cyclic nucleotide-gated potassium channel 0.0019 0.0004 0.0005
Loa Loa (eye worm) hypothetical protein 0.0031 0.0051 0.0147
Schistosoma mansoni tar DNA-binding protein 0.0066 0.0177 0.0213
Echinococcus multilocularis G protein coupled 5 hydroxytryptamine receptor 0.0058 0.0146 0.0171
Trichomonas vaginalis PIKK family atypical protein kinase 0.0035 0.0065 0.0226
Schistosoma mansoni voltage-gated potassium channel 0.0022 0.0017 0.002
Echinococcus granulosus single minded 2 0.0124 0.0388 0.0462
Schistosoma mansoni acetylcholinesterase 0.0063 0.0167 0.0201
Leishmania major cytochrome p450-like protein 0.0042 0.0091 0.0078
Echinococcus granulosus neuropeptide FF receptor 2 0.0058 0.0146 0.0171
Loa Loa (eye worm) short chain dehydrogenase/reductase family oxidoreductase 0.0021 0.0013 0.0036
Schistosoma mansoni voltage-gated potassium channel 0.0019 0.0004 0.0005
Mycobacterium leprae DIHYDROLIPOAMIDE DEHYDROGENASE LPD (LIPOAMIDE REDUCTASE (NADH)) (LIPOYL DEHYDROGENASE) (DIHYDROLIPOYL DEHYDROGENASE) (DIAPHORASE 0.097 0.3481 1
Brugia malayi jmjC domain containing protein 0.0027 0.0036 0.0095
Brugia malayi phosphofructokinase 0.012 0.0375 0.1096
Brugia malayi Nuclear hormone receptor family member nhr-1 0.0019 0.0006 0.0005
Trypanosoma brucei 3-ketoacyl-CoA reductase, putative 0.0021 0.0013 0.0005
Schistosoma mansoni sodium/chloride dependent transporter 0.0038 0.0073 0.0088
Echinococcus multilocularis histone lysine N methyltransferase SETMAR 0.0095 0.0283 0.0336
Trypanosoma brucei beta-ketoacyl-ACP reductase 3, putative 0.0021 0.0013 0.0005
Onchocerca volvulus 0.0108 0.0329 0.1205
Trypanosoma cruzi PAS-domain containing phosphoglycerate kinase, putative 0.0042 0.009 0.0077
Trypanosoma cruzi STE/STE11 serine/threonine-protein kinase, putative 0.0043 0.0094 0.0081
Echinococcus multilocularis nuclear factor of activated T cells 5 0.0154 0.05 0.0597
Trichomonas vaginalis voltage and ligand gated potassium channel, putative 0.0036 0.0067 0.0234
Trichomonas vaginalis PIKK family atypical protein kinase 0.0028 0.0038 0.0128
Echinococcus multilocularis g protein linked acetylcholine receptor gar 2a 0.0058 0.0146 0.0171
Echinococcus multilocularis sodium:chloride dependent neurotransmitter 0.0038 0.0073 0.0083
Loa Loa (eye worm) pigment dispersing factor receptor c 0.0113 0.0349 0.1026
Loa Loa (eye worm) hypothetical protein 0.0021 0.0013 0.0036
Echinococcus granulosus peptide allatostatin:somatostatin 0.0058 0.0146 0.0171
Brugia malayi 6-phosphofructokinase 0.012 0.0376 0.1097
Schistosoma mansoni lipoxygenase 0.0614 0.218 0.2623
Echinococcus granulosus steroid dehydrogenase 0.0021 0.0013 0.0011
Loa Loa (eye worm) jmjC domain-containing protein 0.0027 0.0036 0.0105
Trichomonas vaginalis PIKK family atypical protein kinase 0.0047 0.0109 0.0392
Onchocerca volvulus 0.0753 0.269 1
Brugia malayi Calcitonin receptor-like protein seb-1 0.0113 0.0349 0.1017
Schistosoma mansoni neuropeptide F-like receptor 0.0058 0.0146 0.0176
Loa Loa (eye worm) hypothetical protein 0.0058 0.0146 0.043
Echinococcus granulosus inositol monophosphatase 1 0.0077 0.0219 0.0258
Toxoplasma gondii pyruvate dehydrogenase complex subunit PDH-E3II 0.0753 0.2689 0.7921
Echinococcus granulosus sex peptide receptor 0.0058 0.0146 0.0171
Schistosoma mansoni neuropeptide receptor 0.0058 0.0146 0.0176
Brugia malayi Nuclear hormone receptor family member nhr-49 0.0019 0.0006 0.0005
Echinococcus multilocularis neuroligin 0.0063 0.0167 0.0196
Trichomonas vaginalis glutamate synthase, putative 0.02 0.0667 0.2467
Trichomonas vaginalis disulfide oxidoreductase, putative 0.02 0.0667 0.2467
Echinococcus multilocularis conserved hypothetical protein 0.0728 0.2596 0.3121
Echinococcus granulosus phd:f box containing protein 0.0027 0.0036 0.0039
Schistosoma mansoni sodium/chloride dependent neurotransmitter transporter 0.0038 0.0073 0.0088
Echinococcus multilocularis carboxylesterase 5A 0.0374 0.1302 0.1563
Plasmodium vivax AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.0042 0.0089 0.0226
Echinococcus multilocularis peregrin 0.0031 0.0051 0.0056
Brugia malayi putative neuropeptide receptor NPR1 0.0058 0.0146 0.042
Mycobacterium tuberculosis Probable cytochrome P450 143 Cyp143 0.0042 0.0091 0.0225
Loa Loa (eye worm) oxidoreductase 0.0021 0.0013 0.0036
Schistosoma mansoni family S9 non-peptidase homologue (S09 family) 0.0063 0.0167 0.0201
Echinococcus granulosus 3 ketodihydrosphingosine reductase 0.0021 0.0013 0.0011
Mycobacterium leprae Conserved hypothetical protein 0.0042 0.0091 0.0225
Mycobacterium tuberculosis Possible cytochrome P450 135B1 Cyp135B1 0.0042 0.0091 0.0225
Toxoplasma gondii hypothetical protein 0.0038 0.0073 0.0179
Loa Loa (eye worm) inositol-1 0.0077 0.0219 0.0643
Plasmodium falciparum glutathione reductase 0.0945 0.3391 1
Echinococcus multilocularis oxidoreductase 0.0021 0.0013 0.0011
Trypanosoma cruzi C-8 sterol isomerase, putative 0.0388 0.1356 0.1344
Echinococcus granulosus death domain containing protein 0.003 0.0046 0.0051
Echinococcus granulosus rhodopsin orphan GPCR 0.0058 0.0146 0.0171
Loa Loa (eye worm) thioredoxin reductase 0.0945 0.3391 1
Schistosoma mansoni ubiquitously transcribed sex (X/Y) chromosome tetratricopeptide repeat protein-related 0.0027 0.0036 0.0044
Brugia malayi G-protein-linked acetylcholine receptor protein 2, putative 0.0058 0.0146 0.042
Onchocerca volvulus 0.0058 0.0146 0.0525
Trypanosoma cruzi Present in the outer mitochondrial membrane proteome 4 0.0036 0.0066 0.0054
Echinococcus multilocularis para nitrobenzyl esterase 0.0063 0.0167 0.0196
Schistosoma mansoni peptide (allatostatin/somatostatin)-like receptor 0.0058 0.0146 0.0176
Plasmodium vivax hypothetical protein, conserved 0.0038 0.0073 0.0179
Toxoplasma gondii PHD-finger domain-containing protein 0.0031 0.0051 0.0112
Schistosoma mansoni carbonyl reductase 0.0021 0.0013 0.0015
Echinococcus granulosus lipoxygenase domain containing protein 0.0148 0.0478 0.0571
Onchocerca volvulus 0.0063 0.0167 0.06
Trypanosoma cruzi dihydrolipoyl dehydrogenase, putative 0.0753 0.2689 0.2679
Trichomonas vaginalis carboxylesterase domain containing protein, putative 0.0063 0.0167 0.0606
Loa Loa (eye worm) hypothetical protein 0.0058 0.0146 0.043
Trichomonas vaginalis conserved hypothetical protein 0.0042 0.009 0.032
Mycobacterium ulcerans aldehyde dehydrogenase 0.0067 0.0181 0.063
Trichomonas vaginalis disulfide oxidoreductase, putative 0.02 0.0667 0.2467
Echinococcus granulosus rhodopsin orphan GPCR 0.0058 0.0146 0.0171
Plasmodium vivax ferrodoxin reductase, putative 0.02 0.0667 0.1935
Trichomonas vaginalis ap endonuclease, putative 0.0042 0.0089 0.0317
Brugia malayi Sodium:neurotransmitter symporter family protein 0.0038 0.0073 0.0205
Mycobacterium leprae Probable NADPH:adrenodoxin oxidoreductase FprA (NADPH-FERREDOXIN REDUCTASE) 0.02 0.0667 0.1885
Plasmodium vivax glutathione reductase, putative 0.0945 0.3391 1
Plasmodium vivax ataxin-2 like protein, putative 0.0054 0.0132 0.0353
Onchocerca volvulus 0.0021 0.0013 0.0027
Brugia malayi Serotonin/octopamine receptor family protein 7 0.0058 0.0146 0.042
Mycobacterium leprae PROBABLE NADH DEHYDROGENASE NDH 0.0417 0.1459 0.417
Loa Loa (eye worm) hypothetical protein 0.0058 0.0146 0.043
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0058 0.0146 0.0176
Trypanosoma cruzi PAS-domain containing phosphoglycerate kinase, putative 0.0042 0.009 0.0077
Schistosoma mansoni sulfide quinone reductase 0.02 0.0667 0.0802
Loa Loa (eye worm) nuclear hormone receptor family member nhr-49 0.0019 0.0006 0.0015
Echinococcus multilocularis rhodopsin orphan GPCR 0.0058 0.0146 0.0171
Loa Loa (eye worm) hypothetical protein 0.0058 0.0146 0.043
Echinococcus granulosus tm gpcr rhodopsin 0.0931 0.3339 0.4015
Onchocerca volvulus 0.0021 0.0013 0.0027
Mycobacterium tuberculosis Dihydrolipoamide dehydrogenase LpdC (lipoamide reductase (NADH)) (lipoyl dehydrogenase) (dihydrolipoyl dehydrogenase) (diaphoras 0.097 0.3481 1
Trichomonas vaginalis guanylate cyclase, putative 0.0042 0.009 0.032
Echinococcus multilocularis ecdysone induced protein 78C 0.0019 0.0006 0.0002
Plasmodium falciparum AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.0042 0.0089 0.0242
Leishmania major mitogen activated protein kinase 4, putative;with=GeneDB:LmxM19.1440 0.0109 0.0333 0.032
Entamoeba histolytica phosphofructokinase, putative 0.012 0.0375 0.5544
Trypanosoma cruzi mitogen-activated protein kinase 11, putative 0.0109 0.0333 0.032
Loa Loa (eye worm) hypothetical protein 0.0044 0.0098 0.0287
Brugia malayi hypothetical protein 0.0037 0.0073 0.0203
Loa Loa (eye worm) hypothetical protein 0.0504 0.1777 0.524
Schistosoma mansoni jumonji/arid domain-containing protein 0.0103 0.0312 0.0376
Onchocerca volvulus 0.0058 0.0146 0.0525
Wolbachia endosymbiont of Brugia malayi thioredoxin reductase 0.02 0.0667 0.2443
Leishmania major hypothetical protein, conserved 0.02 0.0667 0.0655
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.0021 0.0013 0.0026
Mycobacterium tuberculosis NADPH-dependent mycothiol reductase Mtr 0.0945 0.3391 0.974
Loa Loa (eye worm) hypothetical protein 0.0021 0.0013 0.0036
Echinococcus granulosus tyrosyl DNA phosphodiesterase 1 0.0072 0.0199 0.0235
Loa Loa (eye worm) nuclear hormone receptor family member nhr-1 0.0019 0.0006 0.0015
Trypanosoma brucei Lanosterol 14-alpha demethylase 0.0185 0.0613 0.0606
Echinococcus multilocularis g protein coupled receptor 0.0058 0.0146 0.0171
Schistosoma mansoni short chain dehydrogenase 0.0021 0.0013 0.0015
Trypanosoma cruzi trypanothione reductase, putative 0.0753 0.2689 0.2679
Echinococcus granulosus GPCR family 2 0.0036 0.0067 0.0075
Loa Loa (eye worm) cytoplasmic intermediate filament protein 0.003 0.0047 0.0135
Brugia malayi latrophilin 2 splice variant baaae 0.0077 0.0218 0.0632
Echinococcus multilocularis g-protein coupled receptor 0.0058 0.0146 0.0171
Echinococcus multilocularis Dehydrogenase:reductase SDR family 0.0021 0.0013 0.0011
Trichomonas vaginalis PIKK family atypical protein kinase 0.0038 0.0074 0.026
Schistosoma mansoni neuroligin 3 (S09 family) 0.0063 0.0167 0.0201
Onchocerca volvulus Glucosylceramidase homolog 0.0179 0.0589 0.2174
Echinococcus multilocularis retinol dehydrogenase 11 0.0021 0.0013 0.0011
Schistosoma mansoni loxhd1 0.0148 0.0478 0.0575
Loa Loa (eye worm) phosphofructokinase 0.012 0.0375 0.1105
Trypanosoma cruzi mitochondrial DNA polymerase beta-PAK, putative 0.0056 0.0139 0.0127
Trichomonas vaginalis PIKK family atypical protein kinase 0.0028 0.0039 0.0132
Trichomonas vaginalis PIKK family atypical protein kinase 0.0028 0.0039 0.0132
Brugia malayi Dehydrogenases, short chain protein 30 0.0021 0.0013 0.0026
Brugia malayi Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain containing protein 0.0553 0.1958 0.5769
Schistosoma mansoni protein phosphatase 2C 0.0027 0.0036 0.0044
Loa Loa (eye worm) cyclic-nucleotide gated cation channel 0.0019 0.0004 0.001
Loa Loa (eye worm) solute carrier family 6 member 4 0.0221 0.0746 0.2197
Loa Loa (eye worm) hypothetical protein 0.0058 0.0146 0.043
Loa Loa (eye worm) exodeoxyribonuclease III family protein 0.0042 0.0089 0.0261
Echinococcus multilocularis serotonin receptor 0.0311 0.1073 0.1287
Trypanosoma brucei ERV/ALR sulfhydryl oxidase domain-containing protein 0.0036 0.0066 0.0058
Schistosoma mansoni thyroid hormone receptor 0.0019 0.0006 0.0007
Schistosoma mansoni short-chain dehydrogenase/reductase 0.0021 0.0013 0.0015
Echinococcus multilocularis rhodopsin orphan GPCR 0.0058 0.0146 0.0171
Echinococcus granulosus survival motor neuron protein 1 0.0504 0.1777 0.2135
Plasmodium vivax multidomain scavenger receptor, putative 0.0148 0.0478 0.1377
Trypanosoma cruzi mitochondrial DNA polymerase beta-PAK, putative 0.0154 0.0498 0.0486
Schistosoma mansoni alpha-1 adrenergic receptor 0.0058 0.0146 0.0176
Mycobacterium tuberculosis Carboxylesterase LipT 0.0063 0.0167 0.0444
Trichomonas vaginalis PIKK family atypical protein kinase 0.0026 0.0029 0.0095
Echinococcus granulosus neuropeptide receptor A26 0.0058 0.0146 0.0171
Leishmania major hypothetical protein, conserved 0.0036 0.0066 0.0054
Mycobacterium tuberculosis Probable cytochrome P450 monooxygenase 142 Cyp142 0.0042 0.0091 0.0225
Schistosoma mansoni single-minded 0.0162 0.0529 0.0637
Mycobacterium ulcerans cytochrome P450 191A3 Cyp191A3 0.0042 0.0091 0.0292
Trypanosoma brucei JmjC domain, hydroxylase, putative 0.0027 0.0036 0.0028
Echinococcus multilocularis G protein coupled receptor 139 0.0058 0.0146 0.0171
Echinococcus granulosus carboxylesterase 5A 0.0374 0.1302 0.1563
Onchocerca volvulus 0.0058 0.0146 0.0525
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.0021 0.0013 0.0026
Plasmodium vivax amine transporter, putative 0.0038 0.0073 0.0179
Trichomonas vaginalis glucosylceramidase, putative 0.0272 0.0932 0.3454
Brugia malayi Steroid receptor seven-up type 2 0.0019 0.0006 0.0005
Echinococcus multilocularis JmjC domain containing protein 4 0.0027 0.0036 0.0039
Trypanosoma brucei short-chain dehydrogenase, putative 0.0021 0.0013 0.0005
Mycobacterium tuberculosis Probable cytochrome P450 137 Cyp137 0.0042 0.0091 0.0225
Trypanosoma cruzi tyrosyl-DNA Phosphodiesterase (Tdp1), putative 0.0072 0.0199 0.0186
Echinococcus multilocularis allatostatin A receptor 0.0058 0.0146 0.0171
Schistosoma mansoni hypothetical protein 0.0058 0.0146 0.0176
Loa Loa (eye worm) hypothetical protein 0.0058 0.0146 0.043
Onchocerca volvulus 0.0034 0.006 0.0202
Trichomonas vaginalis 6-phosphofructokinase, putative 0.0032 0.0055 0.0188
Mycobacterium tuberculosis Probable cytochrome P450 136 Cyp136 0.0042 0.0091 0.0225
Schistosoma mansoni retinoid-x-receptor (RXR) 0.0019 0.0006 0.0007
Loa Loa (eye worm) hypothetical protein 0.0027 0.0036 0.0105
Brugia malayi Carboxylesterase family protein 0.0063 0.0167 0.048
Schistosoma mansoni short chain dehydrogenase 0.0021 0.0013 0.0015
Echinococcus multilocularis sodium and chloride dependent glycine 0.0038 0.0073 0.0083
Echinococcus granulosus sodium channel protein 0.0125 0.0391 0.0466
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.0021 0.0013 0.0026
Schistosoma mansoni amine GPCR 0.0058 0.0146 0.0176
Leishmania major myo-inositol-1(or 4)-monophosphatase 1, putative 0.0077 0.0219 0.0206
Onchocerca volvulus 0.0058 0.0146 0.0525
Giardia lamblia Endonuclease/Exonuclease/phosphatase 0.0042 0.0089 0.0285
Schistosoma mansoni hypothetical protein 0.0077 0.0218 0.0262
Trichomonas vaginalis set domain proteins, putative 0.0753 0.2689 1
Mycobacterium ulcerans cytochrome P450 105Q4 Cyp105Q4 0.0042 0.0091 0.0292
Trichomonas vaginalis short-chain dehydrogenase, putative 0.0021 0.0013 0.0033
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0019 0.0006 0.0002
Echinococcus granulosus tm gpcr rhodopsin 0.0058 0.0146 0.0171
Trypanosoma cruzi STE/STE11 serine/threonine-protein kinase, putative 0.0043 0.0094 0.0081
Echinococcus multilocularis dihydropyrimidine dehydrogenase (NADP+) 0.02 0.0667 0.0798
Mycobacterium tuberculosis Possible cytochrome P450 135A1 Cyp135A1 0.0042 0.0091 0.0225
Mycobacterium ulcerans cytochrome P450 187A4 Cyp187A4 0.0042 0.0091 0.0292
Loa Loa (eye worm) hypothetical protein 0.026 0.0887 0.2614
Toxoplasma gondii hypothetical protein 0.0052 0.0127 0.0339
Loa Loa (eye worm) carboxylesterase 0.0063 0.0167 0.049
Loa Loa (eye worm) hypothetical protein 0.0058 0.0146 0.043
Echinococcus granulosus rhodopsin orphan GPCR 0.0058 0.0146 0.0171
Wolbachia endosymbiont of Brugia malayi dihydrolipoamide dehydrogenase E3 component 0.0753 0.2689 1
Toxoplasma gondii aldehyde dehydrogenase 0.0067 0.0181 0.0499
Mycobacterium ulcerans cytochrome P450 185A4 Cyp185A4 0.0061 0.016 0.055
Schistosoma mansoni inositol monophosphatase 0.0077 0.0219 0.0263
Brugia malayi Carboxylesterase family protein 0.0374 0.1302 0.3832
Mycobacterium ulcerans dehydrogenase 0.02 0.0667 0.2443
Loa Loa (eye worm) nuclear hormone receptor family member nhr-41 0.0019 0.0006 0.0015
Loa Loa (eye worm) hypothetical protein 0.0027 0.0036 0.0105
Echinococcus multilocularis neuropeptide FF receptor 2 0.0058 0.0146 0.0171
Giardia lamblia GTOR 0.0047 0.0109 0.036
Loa Loa (eye worm) hypothetical protein 0.0058 0.0146 0.043
Toxoplasma gondii LsmAD domain-containing protein 0.0054 0.0132 0.0353
Schistosoma mansoni sodium-dependent neurotransmitter transporter 0.0038 0.0073 0.0088
Trypanosoma brucei C-8 sterol isomerase, putative 0.0388 0.1356 0.1349
Echinococcus multilocularis thyrotropin releasing hormone receptor 0.0058 0.0146 0.0171
Onchocerca volvulus 0.0021 0.0013 0.0027
Brugia malayi hypothetical protein 0.0058 0.0146 0.042
Onchocerca volvulus 0.0038 0.0073 0.0253
Echinococcus granulosus WW domain containing oxidoreductase 0.0021 0.0013 0.0011
Brugia malayi nuclear receptor NHR-88 0.0019 0.0006 0.0005
Echinococcus granulosus dihydrolipoamide dehydrogenase 0.0753 0.2689 0.3232
Echinococcus multilocularis lysine specific demethylase 6a 0.0027 0.0036 0.0039
Trypanosoma cruzi apurinic/apyrimidinic endonuclease, putative 0.0042 0.0089 0.0076
Brugia malayi putative neuropeptide receptor 0.0058 0.0146 0.042
Trichomonas vaginalis inositol monophosphatase, putative 0.0077 0.0219 0.08
Echinococcus granulosus netrin receptor unc 5 0.003 0.0046 0.0051
Echinococcus granulosus neuropeptide receptor 0.0058 0.0146 0.0171
Loa Loa (eye worm) hypothetical protein 0.0058 0.0146 0.043
Echinococcus granulosus ecdysone induced protein 78C 0.0019 0.0006 0.0002
Brugia malayi Dopamine receptor protein 1 0.0058 0.0146 0.042
Echinococcus granulosus g protein linked acetylcholine receptor gar 2a 0.0058 0.0146 0.0171
Brugia malayi D-beta-hydroxybutyrate dehydrogenase, mitochondrial precursor 0.0021 0.0013 0.0026
Mycobacterium ulcerans glutamate synthase subunit beta 0.02 0.0667 0.2443
Trichomonas vaginalis glucosylceramidase, putative 0.0272 0.0932 0.3454
Plasmodium vivax dihydrolipoyl dehydrogenase, apicoplast, putative 0.0753 0.2689 0.7921
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.0021 0.0013 0.0026
Echinococcus multilocularis dro:myosuppressin receptor 0.0058 0.0146 0.0171
Echinococcus granulosus tachykinin peptides receptor 99D 0.0058 0.0146 0.0171
Loa Loa (eye worm) oxidoreductase 0.0021 0.0013 0.0036
Echinococcus granulosus dihydropyrimidine dehydrogenase NADP 0.02 0.0667 0.0798
Echinococcus granulosus g protein coupled receptor 0.0058 0.0146 0.0171
Echinococcus multilocularis rhodopsin orphan GPCR 0.0058 0.0146 0.0171
Toxoplasma gondii Erv1 / Alr family protein 0.0036 0.0066 0.0158
Loa Loa (eye worm) RNA binding protein 0.0066 0.0177 0.0519
Echinococcus granulosus DNA apurinic or apyrimidinic site lyase 0.0042 0.0089 0.0103
Echinococcus multilocularis neuropeptide receptor A26 0.0058 0.0146 0.0171
Loa Loa (eye worm) hypothetical protein 0.0019 0.0004 0.001
Plasmodium falciparum transporter, putative 0.0038 0.0073 0.0196
Loa Loa (eye worm) phosphatidylinositol 3 0.0047 0.0109 0.032
Brugia malayi Thioredoxin reductase 0.0945 0.3391 1
Schistosoma mansoni steroid dehydrogenase 0.0021 0.0013 0.0015
Loa Loa (eye worm) hypothetical protein 0.0019 0.0006 0.0015
Echinococcus multilocularis acetylcholinesterase 0.0374 0.1302 0.1563
Trichomonas vaginalis glutathione reductase, putative 0.0753 0.2689 0.9998
Trichomonas vaginalis glucosylceramidase, putative 0.0179 0.0589 0.2179
Schistosoma mansoni glutamate synthase 0.02 0.0667 0.0802
Schistosoma mansoni norepinephrine/norepinephrine transporter 0.0221 0.0746 0.0897
Echinococcus multilocularis apoptosis inducing factor 1 mitochondrial 0.02 0.0667 0.0798
Brugia malayi Pyridine nucleotide-disulphide oxidoreductase family protein 0.02 0.0667 0.1956
Plasmodium falciparum dihydrolipoyl dehydrogenase, mitochondrial 0.0753 0.2689 0.7924
Loa Loa (eye worm) hypothetical protein 0.0058 0.0146 0.043
Trypanosoma brucei dihydrolipoyl dehydrogenase 0.0753 0.2689 0.2683
Loa Loa (eye worm) hypothetical protein 0.0221 0.0746 0.2197
Echinococcus multilocularis 0.0042 0.0091 0.0105
Trichomonas vaginalis phosphofructokinase, putative 0.0032 0.0055 0.0188
Schistosoma mansoni nuclear hormone receptor 0.0019 0.0006 0.0007
Schistosoma mansoni peptide (FMRFamide/somatostatin)-like receptor 0.0058 0.0146 0.0176
Trichomonas vaginalis dihydroorotate dehydrogenase, putative 0.02 0.0667 0.2467
Loa Loa (eye worm) hypothetical protein 0.0058 0.0146 0.043
Brugia malayi neuropeptide F receptor 0.0058 0.0146 0.042
Schistosoma mansoni hypothetical protein 0.0217 0.073 0.0879
Loa Loa (eye worm) hypothetical protein 0.0021 0.0013 0.0036
Onchocerca volvulus 0.0058 0.0146 0.0525
Echinococcus granulosus hypothetical protein 0.0785 0.2807 0.3374
Schistosoma mansoni norepinephrine/norepinephrine transporter 0.0038 0.0073 0.0088
Mycobacterium tuberculosis Probable reductase 0.0417 0.1459 0.417
Loa Loa (eye worm) 5-hydroxytryptamine 2C receptor 0.0058 0.0146 0.043
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0019 0.0006 0.0005
Loa Loa (eye worm) hypothetical protein 0.0095 0.0283 0.0833
Toxoplasma gondii NADPH-glutathione reductase 0.0753 0.2689 0.7921
Loa Loa (eye worm) hypothetical protein 0.0058 0.0146 0.043
Echinococcus multilocularis Polycystic kidney disease protein 0.0148 0.0478 0.0571
Trichomonas vaginalis short-chain dehydrogenase, putative 0.0021 0.0013 0.0033
Brugia malayi Nuclear hormone receptor-like 1 0.0019 0.0006 0.0005
Echinococcus granulosus geminin 0.0378 0.1317 0.1581
Echinococcus multilocularis neuropeptide Y receptor 0.0058 0.0146 0.0171
Loa Loa (eye worm) cytochrome P450 family protein 0.0061 0.016 0.047
Schistosoma mansoni 6-phosphofructokinase 0.012 0.0375 0.0452
Schistosoma mansoni tar DNA-binding protein 0.0066 0.0177 0.0213
Loa Loa (eye worm) serotonin transporter b 0.0221 0.0746 0.2197
Echinococcus granulosus microtubule associated protein 2 0.2291 0.831 1
Brugia malayi intermediate filament protein 0.0056 0.0142 0.0409
Brugia malayi Voltage-gated potassium channel, EAG (KCNH1)-related. C. elegans egl-2 ortholog 0.0022 0.0017 0.0038
Echinococcus granulosus rhodopsin orphan GPCR 0.0058 0.0146 0.0171
Toxoplasma gondii phosphofructokinase domain-containing protein 0.0032 0.0055 0.0124
Leishmania major dihydrolipoamide dehydrogenase, putative 0.0753 0.2689 0.2679
Brugia malayi hypothetical protein 0.0058 0.0146 0.042
Loa Loa (eye worm) hypothetical protein 0.0021 0.0013 0.0036
Loa Loa (eye worm) hypothetical protein 0.0221 0.0746 0.2197
Schistosoma mansoni sodium/chloride dependent transporter 0.0221 0.0746 0.0897
Echinococcus multilocularis mitogen activated protein kinase 0.0109 0.0333 0.0396
Toxoplasma gondii inositol(myo)-1(or 4)-monophosphatase 2, putative 0.0077 0.0219 0.061
Echinococcus granulosus potassium voltage gated channel subfamily H 0.0022 0.0017 0.0016
Trichomonas vaginalis chromobox protein, putative 0.0046 0.0106 0.0379
Mycobacterium ulcerans cytochrome P450 144A4 Cyp144A4 0.0042 0.0091 0.0292
Brugia malayi Iron-sulfur cluster assembly accessory protein 0.0103 0.0312 0.0908
Plasmodium falciparum ATP-dependent 6-phosphofructokinase 0.0032 0.0055 0.014
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.0021 0.0013 0.0026
Echinococcus granulosus jumonji domain containing protein 0.0044 0.0095 0.011
Trypanosoma cruzi dihydrolipoyl dehydrogenase, putative 0.0753 0.2689 0.2679
Loa Loa (eye worm) oxidoreductase 0.0021 0.0013 0.0036
Echinococcus granulosus potassium voltage gated channel subfamily H 0.0049 0.0117 0.0135
Brugia malayi G-protein coupled receptor 0.0058 0.0146 0.042
Brugia malayi G protein-coupled receptor 0.0058 0.0146 0.042
Brugia malayi Serotonin receptor 0.0543 0.192 0.5657
Loa Loa (eye worm) hypothetical protein 0.0221 0.0746 0.2197
Loa Loa (eye worm) hepatopoietin HPO2 0.0036 0.0066 0.0194
Brugia malayi chromobox protein homolog 3 0.0043 0.0094 0.0265
Brugia malayi Nuclear hormone receptor family member nhr-14 0.0019 0.0006 0.0005
Trichomonas vaginalis CMGC family protein kinase 0.0109 0.0333 0.1224
Loa Loa (eye worm) hypothetical protein 0.0038 0.0073 0.0215
Brugia malayi PHD-finger family protein 0.0031 0.0051 0.0137
Mycobacterium ulcerans hypothetical protein 0.0171 0.0561 0.205
Echinococcus multilocularis retinol dehydrogenase 11 0.0021 0.0013 0.0011
Schistosoma mansoni cyclic-nucleotide-gated cation channel 0.0019 0.0004 0.0005
Mycobacterium ulcerans ferredoxin reductase 0.02 0.0667 0.2443
Plasmodium vivax FAD-linked sulfhydryl oxidase ERV1, putative 0.0036 0.0066 0.0158
Mycobacterium tuberculosis Probable cytochrome P450 132 Cyp132 0.0042 0.0091 0.0225
Loa Loa (eye worm) 6-phosphofructokinase 0.012 0.0375 0.1105
Entamoeba histolytica phosphofructokinase, putative 0.012 0.0375 0.5544
Loa Loa (eye worm) hypothetical protein 0.0058 0.0146 0.043
Loa Loa (eye worm) acetylcholinesterase 1 0.0374 0.1302 0.3838
Brugia malayi G-protein coupled receptor 0.0058 0.0146 0.042
Trypanosoma cruzi PAB1-binding protein , putative 0.0054 0.0132 0.012
Mycobacterium leprae Possible regulatory protein 0.0042 0.009 0.0223
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.2018 0.7315 0.7312
Mycobacterium tuberculosis POSSIBLE PARA-NITROBENZYL ESTERASE (FRAGMENT) 0.0063 0.0167 0.0444
Onchocerca volvulus 0.0221 0.0746 0.2756
Schistosoma mansoni neuropeptide receptor 0.0058 0.0146 0.0176
Echinococcus granulosus cytochrome P450 2K1 0.0042 0.0091 0.0105
Echinococcus multilocularis FTZ F1 nuclear receptor protein 0.0019 0.0006 0.0002
Echinococcus multilocularis thioredoxin glutathione reductase 0.0945 0.3391 0.4078
Schistosoma mansoni aryl hydrocarbon receptor 0.0162 0.0529 0.0637
Loa Loa (eye worm) hypothetical protein 0.0036 0.0067 0.0194
Trypanosoma cruzi apurinic/apyrimidinic endonuclease 0.0042 0.0089 0.0076
Trypanosoma brucei oxidoreductase-like protein 0.0021 0.0013 0.0005
Loa Loa (eye worm) hypothetical protein 0.0022 0.0017 0.0048
Schistosoma mansoni steroid dehydrogenase 0.0021 0.0013 0.0015
Loa Loa (eye worm) hypothetical protein 0.0021 0.0013 0.0036
Loa Loa (eye worm) hypothetical protein 0.0038 0.0073 0.0215
Echinococcus granulosus carbonyl reductase 1 0.0021 0.0013 0.0011
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0047 0.0106 0.0123
Toxoplasma gondii phosphofructokinase PFKII 0.0032 0.0055 0.0124
Schistosoma mansoni microtubule-associated protein tau 0.2291 0.831 1
Plasmodium vivax type II NADH:ubiquinone oxidoreductase, putative 0.02 0.0667 0.1935
Trichomonas vaginalis conserved hypothetical protein 0.0031 0.0048 0.0163
Trichomonas vaginalis PIKK family atypical protein kinase 0.0026 0.0029 0.0095
Loa Loa (eye worm) neuropeptide F receptor 0.0058 0.0146 0.043
Echinococcus multilocularis geminin 0.0378 0.1317 0.1581
Trypanosoma brucei short-chain dehydrogenase, putative 0.0021 0.0013 0.0005
Loa Loa (eye worm) carboxylesterase 0.0063 0.0167 0.049
Loa Loa (eye worm) intermediate filament protein 0.0056 0.0142 0.0418
Echinococcus multilocularis voltage gated potassium channel 0.0022 0.0017 0.0016
Trichomonas vaginalis hydroxyacyl dehydrogenase, putative 0.0021 0.0013 0.0033
Echinococcus multilocularis Aryl hydrocarbon receptor nuclear 0.0042 0.009 0.0104
Trichomonas vaginalis PIKK family atypical protein kinase 0.0032 0.0052 0.0179
Brugia malayi Inositol-1 0.0077 0.0219 0.0634
Echinococcus granulosus Jumonji AT rich interactive domain 1B 0.0027 0.0036 0.0039
Brugia malayi jmjC domain containing protein 0.0168 0.0549 0.1609
Schistosoma mansoni jumonji domain containing protein 0.0147 0.0472 0.0568
Echinococcus multilocularis tar DNA binding protein 0.0066 0.0177 0.0208
Schistosoma mansoni short chain dehydrogenase 0.0021 0.0013 0.0015
Loa Loa (eye worm) hypothetical protein 0.0388 0.1356 0.3996
Schistosoma mansoni jumonji domain containing protein 0.0027 0.0036 0.0044
Echinococcus multilocularis glutamate synthase 0.02 0.0667 0.0798
Leishmania major acetoin dehydrogenase e3 component-like protein 0.2018 0.7315 0.7312
Schistosoma mansoni sodium/chloride dependent neurotransmitter transporter 0.0038 0.0073 0.0088
Trichomonas vaginalis guanylate cyclase, putative 0.0042 0.009 0.032
Onchocerca volvulus Dopamine\/Ecdysteroid receptor homolog 0.0058 0.0146 0.0525
Echinococcus granulosus intermediate filament protein 0.0056 0.0142 0.0167
Loa Loa (eye worm) TYRA-2 protein 0.0058 0.0146 0.043
Onchocerca volvulus Netrin receptor homolog 0.003 0.0046 0.0151
Leishmania major lanosterol 14-alpha-demethylase, putative 0.0185 0.0613 0.0601
Trypanosoma brucei 2,4-dienoyl-coa reductase-like protein 0.02 0.0667 0.0659
Loa Loa (eye worm) dehydrogenase 0.0021 0.0013 0.0036
Echinococcus multilocularis FKBP12 rapamycin complex associated protein 0.0047 0.0109 0.0127
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.2313 0.8392 0.839
Loa Loa (eye worm) nuclear hormone receptor family member nhr-14 0.0019 0.0006 0.0015
Schistosoma mansoni jumonji/arid domain-containing protein 0.0103 0.0312 0.0376
Schistosoma mansoni steroid dehydrogenase 0.0021 0.0013 0.0015
Brugia malayi Sodium:neurotransmitter symporter family protein 0.0221 0.0746 0.2189
Schistosoma mansoni phd/f-box containing protein 0.0027 0.0036 0.0044
Schistosoma mansoni hypothetical protein 0.0036 0.0067 0.008
Loa Loa (eye worm) hypothetical protein 0.003 0.0046 0.0134
Brugia malayi exodeoxyribonuclease III family protein 0.0042 0.0089 0.0251
Echinococcus granulosus FTZ F1 alpha 0.0019 0.0006 0.0002
Echinococcus multilocularis carbonyl reductase 1 0.0021 0.0013 0.0011
Loa Loa (eye worm) hypothetical protein 0.0058 0.0146 0.043
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0058 0.0146 0.0176
Brugia malayi cytoplasmic intermediate filament protein 0.003 0.0047 0.0125
Echinococcus granulosus neuroligin 0.0063 0.0167 0.0196
Loa Loa (eye worm) hypothetical protein 0.0042 0.009 0.0264
Trypanosoma cruzi mitogen activated protein kinase 2, putative 0.0109 0.0333 0.032
Trichomonas vaginalis chromobox protein, putative 0.0077 0.0218 0.0795
Echinococcus multilocularis jun protein 0.0267 0.0914 0.1095
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0058 0.0146 0.0176
Echinococcus multilocularis pyridine nucleotide disulfide oxidoreductase 0.02 0.0667 0.0798
Schistosoma mansoni voltage-gated potassium channel 0.0053 0.0129 0.0156
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0047 0.0106 0.0128
Trichomonas vaginalis glucosylceramidase, putative 0.0179 0.0589 0.2179
Entamoeba histolytica pyridine nucleotide-disulfide oxidoreductase family protein 0.02 0.0667 1
Trichomonas vaginalis phosphofructokinase, putative 0.0032 0.0055 0.0188
Brugia malayi Cytochrome P450 family protein 0.0065 0.0174 0.0501
Loa Loa (eye worm) hypothetical protein 0.0077 0.0218 0.0641
Loa Loa (eye worm) hypothetical protein 0.0019 0.0006 0.0015
Schistosoma mansoni BC026374 protein (S09 family) 0.0063 0.0167 0.0201
Schistosoma mansoni neuropeptide receptor 0.0058 0.0146 0.0176
Loa Loa (eye worm) cytochrome P450 family protein 0.0065 0.0174 0.0511
Trichomonas vaginalis CMGC family protein kinase 0.0109 0.0333 0.1224
Trypanosoma cruzi target of rapamycin kinase 3 0.0038 0.0074 0.0061
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.0021 0.0013 0.0026
Leishmania major ATP-dependent phosphofructokinase 0.012 0.0375 0.0363
Onchocerca volvulus 0.0063 0.0167 0.06
Mycobacterium leprae possible inositol monophosphatase SubH (IMPase) (inositol-1-phosphatase) (I-1-Pase ). 0.0069 0.0189 0.0508
Schistosoma mansoni jun-related protein 0.0217 0.073 0.0879
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0058 0.0146 0.0176
Mycobacterium ulcerans short-chain type dehydrogenase/reductase 0.0195 0.0649 0.2376
Chlamydia trachomatis two component regulatory system sensor histidine kinase 0.0042 0.009 0.0135
Schistosoma mansoni amine GPCR 0.0058 0.0146 0.0176
Schistosoma mansoni short chain dehydrogenase 0.0021 0.0013 0.0015
Loa Loa (eye worm) hypothetical protein 0.0058 0.0146 0.043
Mycobacterium tuberculosis Probable NADH dehydrogenase Ndh 0.0417 0.1459 0.417
Loa Loa (eye worm) hypothetical protein 0.0019 0.0006 0.0015
Schistosoma mansoni hypothetical protein 0.0024 0.0024 0.0029
Echinococcus granulosus sodium and chloride dependent glycine 0.0038 0.0073 0.0083
Trypanosoma brucei hypothetical protein, conserved 0.02 0.0667 0.0659
Loa Loa (eye worm) hypothetical protein 0.0058 0.0146 0.043
Leishmania major mitochondrial DNA polymerase beta-PAK, putative 0.0154 0.0498 0.0486
Echinococcus granulosus g protein coupled receptor 0.0058 0.0146 0.0171
Mycobacterium ulcerans cytochrome P450 51B1 Cyp51B1 0.0185 0.0613 0.2244
Brugia malayi G protein-coupled receptor F59B2.13 0.0058 0.0146 0.042
Trichomonas vaginalis short-chain dehydrogenase, putative 0.0021 0.0013 0.0033
Plasmodium falciparum conserved Plasmodium protein, unknown function 0.0021 0.0013 0.0017
Echinococcus granulosus mitogen activated protein kinase 3 0.0109 0.0333 0.0396
Echinococcus granulosus chromobox protein 1 0.0077 0.0218 0.0257
Schistosoma mansoni hypothetical protein 0.0036 0.0067 0.008
Echinococcus granulosus FKBP12 rapamycin complex associated protein 0.0047 0.0109 0.0127
Loa Loa (eye worm) oxidoreductase 0.0021 0.0013 0.0036
Leishmania major hypothetical protein, conserved 0.02 0.0667 0.0655
Trichomonas vaginalis PIKK family atypical protein kinase 0.0026 0.0029 0.0095
Giardia lamblia NADH oxidase lateral transfer candidate 0.0753 0.2689 1
Mycobacterium tuberculosis NAD(P)H quinone reductase LpdA 0.097 0.3481 1
Echinococcus granulosus 7TM GPCR rhodopsin 0.0058 0.0146 0.0171
Wolbachia endosymbiont of Brugia malayi dihydrolipoamide dehydrogenase E3 component 0.0753 0.2689 1
Loa Loa (eye worm) hypothetical protein 0.0063 0.0167 0.049
Trichomonas vaginalis disulfide oxidoreductase, putative 0.02 0.0667 0.2467
Schistosoma mansoni tar DNA-binding protein 0.0066 0.0177 0.0213
Brugia malayi photoreceptor-specific nuclear receptor 0.0019 0.0006 0.0005
Echinococcus multilocularis tachykinin peptides receptor 99D 0.0058 0.0146 0.0171
Onchocerca volvulus 0.0058 0.0146 0.0525
Echinococcus multilocularis dihydrolipoamide dehydrogenase 0.0753 0.2689 0.3232
Mycobacterium ulcerans thioredoxin reductase TrxB2 0.02 0.0667 0.2443
Trichomonas vaginalis short-chain dehydrogenase, putative 0.0021 0.0013 0.0033
Brugia malayi Sodium:neurotransmitter symporter family protein 0.0038 0.0073 0.0205
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0019 0.0006 0.0002
Loa Loa (eye worm) oxidoreductase 0.0021 0.0013 0.0036
Loa Loa (eye worm) hypothetical protein 0.0021 0.0013 0.0036
Loa Loa (eye worm) G-protein coupled receptor 0.0058 0.0146 0.043
Brugia malayi hypothetical protein 0.0058 0.0146 0.042
Echinococcus granulosus neuropeptide s receptor 0.0058 0.0146 0.0171
Brugia malayi Latrophilin receptor protein 2 0.0036 0.0067 0.0184
Brugia malayi gonadotropin-releasing hormone receptor 2 0.0058 0.0146 0.042
Echinococcus multilocularis NADPH:adrenodoxin oxidoreductase 0.02 0.0667 0.0798
Mycobacterium ulcerans monoxygenase 0.02 0.0667 0.2443
Onchocerca volvulus 0.0058 0.0146 0.0525
Loa Loa (eye worm) neuropeptide F receptor 0.0058 0.0146 0.043
Loa Loa (eye worm) hypothetical protein 0.0058 0.0146 0.043
Echinococcus granulosus Aryl hydrocarbon receptor nuclear 0.0042 0.009 0.0104
Loa Loa (eye worm) hypothetical protein 0.0058 0.0146 0.043
Leishmania major 2,4-dienoyl-coa reductase fadh1, putative 0.02 0.0667 0.0655
Schistosoma mansoni sodium-dependent neurotransmitter transporter 0.0038 0.0073 0.0088
Schistosoma mansoni biogenic amine receptor 0.0058 0.0146 0.0176
Trypanosoma cruzi DNA polymerase beta thumb, putative 0.0046 0.0103 0.009
Loa Loa (eye worm) hypothetical protein 0.0063 0.0167 0.049
Brugia malayi Augmenter of liver regeneration 0.0036 0.0066 0.0184
Schistosoma mansoni tyrosyl-DNA phosphodiesterase 0.0072 0.0199 0.024
Echinococcus multilocularis mitogen activated protein kinase 3 0.0109 0.0333 0.0396
Mycobacterium ulcerans 6-phosphofructokinase 0.012 0.0375 0.1354
Trichomonas vaginalis phosphofructokinase, putative 0.012 0.0375 0.1382
Brugia malayi ecdysteroid receptor 0.0019 0.0006 0.0005
Trypanosoma cruzi 2,4-dienoyl-coa reductase-like protein, putative 0.02 0.0667 0.0655
Schistosoma mansoni retinoblastoma-binding protein 4 (rbbp4) 0.003 0.0047 0.0057
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.0021 0.0013 0.0026
Onchocerca volvulus 0.0103 0.0312 0.114
Onchocerca volvulus Alhambra homolog 0.0031 0.0051 0.0167
Mycobacterium leprae putative cytochrome p450 0.0042 0.0091 0.0225
Echinococcus multilocularis dihydropyrimidine dehydrogenase (NADP+) 0.02 0.0667 0.0798
Mycobacterium tuberculosis Probable cytochrome P450 128 Cyp128 0.0042 0.0091 0.0225
Echinococcus granulosus cytoplasmic intermediate filament protein 0.0027 0.0036 0.0038
Loa Loa (eye worm) jmjC domain-containing protein 0.0065 0.0173 0.0507
Schistosoma mansoni neuropeptide F-like receptor 0.0058 0.0146 0.0176
Mycobacterium ulcerans cytochrome P450 123A3 Cyp123A3 0.0042 0.0091 0.0292
Echinococcus multilocularis Ankyrin 0.003 0.0047 0.0052
Trichomonas vaginalis chromobox protein, putative 0.0046 0.0106 0.0379
Brugia malayi hypothetical protein 0.0063 0.0167 0.048
Leishmania major 2-oxoglutarate dehydrogenase, e3 component, lipoamidedehydrogenase-like protein 0.2313 0.8392 0.839
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0058 0.0146 0.0176
Brugia malayi hypothetical protein 0.0544 0.1926 0.5673
Plasmodium falciparum JmjC domain-containing protein, putative 0.0027 0.0036 0.0086
Schistosoma mansoni sulfide quinone reductase 0.02 0.0667 0.0802
Leishmania major mitogen activated protein kinase, putative,map kinase, putative 0.0109 0.0333 0.032
Treponema pallidum thioredoxin reductase (trxB) 0.02 0.0667 0.2323
Trypanosoma cruzi 2,4-dienoyl-coa reductase fadh1, putative 0.02 0.0667 0.0655
Leishmania major target of rapamycin kinase (TOR) kinase 3 0.0038 0.0074 0.0061
Trichomonas vaginalis PIKK family atypical protein kinase 0.0035 0.0065 0.0226
Schistosoma mansoni tar DNA-binding protein 0.0066 0.0177 0.0213
Loa Loa (eye worm) hypothetical protein 0.003 0.0047 0.0137
Echinococcus multilocularis sodium dependent neurotransmitter transporter 0.0038 0.0073 0.0083
Loa Loa (eye worm) hypothetical protein 0.0038 0.0073 0.0215
Loa Loa (eye worm) jmjC domain-containing protein 0.0027 0.0036 0.0105
Echinococcus multilocularis cytoplasmic intermediate filament protein 0.0027 0.0036 0.0038
Toxoplasma gondii cytochrome p450 superfamily protein 0.0042 0.0091 0.0231
Loa Loa (eye worm) hypothetical protein 0.0058 0.0146 0.043
Schistosoma mansoni biogenic amine (octopamine/dopamine) receptor 0.0058 0.0146 0.0176
Trichomonas vaginalis DNA helicase recq1, putative 0.0022 0.0017 0.0048
Echinococcus granulosus G protein coupled receptor 139 0.0058 0.0146 0.0171
Schistosoma mansoni nuclear hormone receptor nor-1/nor-2 0.0019 0.0006 0.0007
Echinococcus multilocularis serotonin receptor 0.0311 0.1073 0.1287
Loa Loa (eye worm) oxidoreductase 0.0021 0.0013 0.0036
Schistosoma mansoni cyclic-nucleotide-gated cation channel 0.0019 0.0004 0.0005
Onchocerca volvulus 0.0063 0.0167 0.06
Mycobacterium ulcerans hypothetical protein 0.02 0.0667 0.2443
Trichomonas vaginalis glucosylceramidase, putative 0.0272 0.0932 0.3454
Trichomonas vaginalis conserved hypothetical protein 0.0043 0.0094 0.0334
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0019 0.0006 0.0005
Schistosoma mansoni photoreceptor-specific nuclear receptor related 0.0019 0.0006 0.0007
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.0021 0.0013 0.0026
Loa Loa (eye worm) hypothetical protein 0.0311 0.1073 0.3164
Loa Loa (eye worm) hypothetical protein 0.0038 0.0073 0.0215
Trichomonas vaginalis DNA helicase recq, putative 0.0022 0.0017 0.0048
Trichomonas vaginalis PIKK family atypical protein kinase 0.0038 0.0074 0.026
Schistosoma mansoni netrin receptor unc5 0.003 0.0046 0.0055
Echinococcus granulosus retinol dehydrogenase 11 0.0021 0.0013 0.0011
Brugia malayi hypothetical protein 0.0054 0.0132 0.0378
Echinococcus granulosus transcription factor Dp 1 0.0042 0.0088 0.0101
Schistosoma mansoni 3-hydroxyacyl-CoA dehydrogenase 0.0195 0.0649 0.0781
Echinococcus multilocularis sulfide:quinone oxidoreductase 0.02 0.0667 0.0798
Loa Loa (eye worm) hypothetical protein 0.0058 0.0146 0.043
Loa Loa (eye worm) doublecortin family protein 0.0148 0.0478 0.1408
Echinococcus multilocularis retinol dehydrogenase 13 0.0021 0.0013 0.0011
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0047 0.0106 0.0123
Mycobacterium leprae Probable NADH-dependent glutamate synthase (small subunit) GltD (L-glutamate synthase) (L-glutamate synthetase) (NADH-glutamate 0.02 0.0667 0.1885
Onchocerca volvulus 0.021 0.0704 0.26
Loa Loa (eye worm) hypothetical protein 0.0148 0.0478 0.1408
Leishmania major cytochrome p450-like protein 0.0061 0.016 0.0147
Echinococcus multilocularis neuropeptides capa receptor 0.0058 0.0146 0.0171
Trichomonas vaginalis conserved hypothetical protein 0.0031 0.0048 0.0163
Schistosoma mansoni norepinephrine/norepinephrine transporter 0.0038 0.0073 0.0088
Trypanosoma brucei dihydrolipoamide dehydrogenase 0.2753 1 1
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0019 0.0006 0.0005
Echinococcus granulosus acetylcholinesterase 0.0374 0.1302 0.1563
Brugia malayi Voltage-gated potassium channel, HERG (KCNH2)-related. C. elegans unc-103 ortholog 0.0049 0.0117 0.0332
Trichomonas vaginalis glucosylceramidase, putative 0.0179 0.0589 0.2179
Echinococcus granulosus g protein coupled receptor 0.0058 0.0146 0.0171
Mycobacterium ulcerans carboxylesterase, LipT 0.0063 0.0167 0.0575
Plasmodium falciparum ataxin-2 like protein, putative 0.0054 0.0132 0.0369
Loa Loa (eye worm) pyridine nucleotide-disufhide oxidoreductase 0.02 0.0667 0.1964
Onchocerca volvulus Sepiapterin reductase homolog 0.0021 0.0013 0.0027
Toxoplasma gondii Sodium:neurotransmitter symporter family protein 0.0038 0.0073 0.0179
Echinococcus multilocularis lamin 0.0056 0.0142 0.0167
Echinococcus granulosus COUP TF:Svp nuclear hormone receptor 0.0019 0.0006 0.0002
Trypanosoma cruzi tyrosyl-DNA Phosphodiesterase (Tdp1), putative 0.0072 0.0199 0.0186
Schistosoma mansoni short chain dehydrogenase 0.0021 0.0013 0.0015
Leishmania major 2,4-dienoyl-coa reductase-like protein 0.02 0.0667 0.0655
Brugia malayi 3-hydroxyacyl-CoA dehydrogenase type II 0.0195 0.0649 0.1903
Echinococcus granulosus uncharacterized sodium dependent transporter 0.0038 0.0073 0.0083
Echinococcus granulosus aldehyde dehydrogenase mitochondrial 0.0067 0.0181 0.0213
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.2753 1 1
Toxoplasma gondii target of rapamycin (TOR), putative 0.0035 0.0065 0.0154
Trypanosoma brucei NADPH:adrenodoxin oxidoreductase, mitochondrial, putative 0.02 0.0667 0.0659
Echinococcus multilocularis g protein coupled receptor 0.0058 0.0146 0.0171
Schistosoma mansoni hypothetical protein 0.0378 0.1317 0.1585
Brugia malayi Corticotropin releasing factor receptor 2 precursor, putative 0.0113 0.0349 0.1017
Echinococcus granulosus oxidoreductase 0.0021 0.0013 0.0011
Mycobacterium ulcerans NADPH dependent 2,4-dienoyl-CoA reductase FadH 0.02 0.0667 0.2443
Loa Loa (eye worm) cyclic-nucleotide gated cation channel 0.0019 0.0004 0.001
Schistosoma mansoni short chain dehydrogenase 0.0021 0.0013 0.0015
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0095 0.0283 0.034
Schistosoma mansoni family S9 non-peptidase homologue (S09 family) 0.0063 0.0167 0.0201
Schistosoma mansoni family S9 non-peptidase homologue (S09 family) 0.0063 0.0167 0.0201
Schistosoma mansoni 6-phosphofructokinase 0.012 0.0375 0.0452
Brugia malayi TAR-binding protein 0.0066 0.0177 0.051
Loa Loa (eye worm) hypothetical protein 0.0021 0.0013 0.0036
Trypanosoma cruzi mitogen-activated protein kinase 11, putative 0.0109 0.0333 0.032
Schistosoma mansoni steroid dehydrogenase 0.0021 0.0013 0.0015
Echinococcus multilocularis GPCR, family 2 0.0036 0.0067 0.0075
Loa Loa (eye worm) cytochrome P450 family protein 0.0061 0.016 0.047
Entamoeba histolytica disulphide oxidoreductase, putative 0.02 0.0667 1
Trypanosoma brucei beta-D-hydroxybutyrate dehydrogenase 0.0021 0.0013 0.0005
Trichomonas vaginalis myo inositol monophosphatase, putative 0.0077 0.0219 0.08
Schistosoma mansoni histamine-responsive GPCR (AAF21638) 0.0058 0.0146 0.0176
Echinococcus multilocularis estradiol 17 beta dehydrogenase 12 0.0021 0.0013 0.0011
Echinococcus granulosus lysine specific demethylase 5A 0.0103 0.0312 0.0371
Echinococcus multilocularis fmrfamide receptor 0.0058 0.0146 0.0171
Onchocerca volvulus 0.0021 0.0013 0.0027
Trichomonas vaginalis PIKK family atypical protein kinase 0.004 0.0084 0.0297
Echinococcus granulosus RUN 0.0148 0.0478 0.0571
Entamoeba histolytica phosphofructokinase, putative 0.012 0.0375 0.5544
Trypanosoma brucei DNA polymerase beta thumb, putative 0.0046 0.0103 0.0095
Onchocerca volvulus 0.0058 0.0146 0.0525
Brugia malayi hypothetical protein 0.0148 0.0478 0.1399
Echinococcus multilocularis neuropeptide receptor 0.0058 0.0146 0.0171
Schistosoma mansoni carbonyl reductase 0.0021 0.0013 0.0015
Brugia malayi Pre-SET motif family protein 0.0095 0.0283 0.0823
Loa Loa (eye worm) hypothetical protein 0.0058 0.0146 0.043
Schistosoma mansoni short chain dehydrogenase 0.0021 0.0013 0.0015
Echinococcus multilocularis phd:f box containing protein 0.0027 0.0036 0.0039
Plasmodium falciparum ferrodoxin reductase-like protein 0.02 0.0667 0.1949
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0058 0.0146 0.0176
Loa Loa (eye worm) hypothetical protein 0.0019 0.0005 0.0013
Brugia malayi hypothetical protein 0.0058 0.0146 0.042
Trichomonas vaginalis ap endonuclease, putative 0.0042 0.0089 0.0317
Loa Loa (eye worm) hypothetical protein 0.0021 0.0013 0.0036
Trypanosoma cruzi mitogen activated protein kinase 4, putative 0.0109 0.0333 0.032
Loa Loa (eye worm) oxidoreductase 0.0021 0.0013 0.0036
Trichomonas vaginalis glucosylceramidase, putative 0.0272 0.0932 0.3454
Loa Loa (eye worm) follicle stimulating hormone receptor 0.0058 0.0146 0.043
Echinococcus granulosus pyroglutamylated rfamide peptide receptor 0.0058 0.0146 0.0171
Onchocerca volvulus 0.0021 0.0013 0.0027
Onchocerca volvulus Dehydrogenase\/reductase SDR family member 13 homolog 0.0021 0.0013 0.0027
Echinococcus granulosus biogenic amine 5HT receptor 0.0058 0.0146 0.0171
Wolbachia endosymbiont of Brugia malayi NADPH-dependent glutamate synthase beta chain 0.02 0.0667 0.2443
Echinococcus granulosus biogenic amine 5HT receptor 0.0311 0.1073 0.1287
Schistosoma mansoni Tr4/Tr2 (homologue) 0.0019 0.0006 0.0007
Leishmania major trypanothione reductase 0.0945 0.3391 0.3383
Loa Loa (eye worm) G-protein coupled receptor 0.0058 0.0146 0.043
Echinococcus multilocularis ankyrin repeat and death domain containing protein 0.003 0.0046 0.0051
Onchocerca volvulus 0.0058 0.0146 0.0525
Trypanosoma cruzi myo-inositol-1(or 4)-monophosphatase 1, putative 0.0077 0.0219 0.0206
Trichomonas vaginalis glucosylceramidase, putative 0.0179 0.0589 0.2179
Brugia malayi AKH receptor 0.0058 0.0146 0.042
Loa Loa (eye worm) hypothetical protein 0.0058 0.0146 0.043
Loa Loa (eye worm) PHD-finger family protein 0.0031 0.0051 0.0147
Mycobacterium tuberculosis Probable cytochrome P450 124 Cyp124 0.0042 0.0091 0.0225
Brugia malayi 6-phosphofructokinase 0.012 0.0375 0.1096
Loa Loa (eye worm) hypothetical protein 0.0043 0.0094 0.0275
Echinococcus multilocularis neuropeptides capa receptor 0.0058 0.0146 0.0171
Brugia malayi RE15519p 0.0058 0.0146 0.042
Schistosoma mansoni retinoic acid receptor RXR 0.0019 0.0006 0.0007
Echinococcus multilocularis DNA (apurinic or apyrimidinic site) lyase 0.0042 0.0089 0.0103
Loa Loa (eye worm) hypothetical protein 0.0058 0.0146 0.043
Onchocerca volvulus 0.0063 0.0167 0.06
Mycobacterium ulcerans NADH dehydrogenase Ndh 0.02 0.0667 0.2443
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0019 0.0006 0.0002
Trypanosoma brucei ATP-dependent 6-phosphofructokinase, glycosomal 0.012 0.0375 0.0368
Schistosoma mansoni voltage-gated potassium channel 0.0022 0.0017 0.002
Mycobacterium tuberculosis Probable 6-phosphofructokinase PfkA (phosphohexokinase) (phosphofructokinase) 0.012 0.0375 0.1045
Onchocerca volvulus 0.0058 0.0146 0.0525
Loa Loa (eye worm) hypothetical protein 0.0351 0.1218 0.3591
Mycobacterium tuberculosis Probable oxidoreductase 0.097 0.3481 1
Echinococcus multilocularis carbonyl reductase 1 0.0021 0.0013 0.0011
Plasmodium falciparum FAD-linked sulfhydryl oxidase ERV1, putative 0.0036 0.0066 0.0175
Schistosoma mansoni short chain dehydrogenase 0.0021 0.0013 0.0015
Schistosoma mansoni RAR-like nuclear receptor 0.0019 0.0006 0.0007
Echinococcus multilocularis lamin dm0 0.0056 0.0142 0.0167
Schistosoma mansoni biogenic amine receptor 0.0058 0.0146 0.0176
Echinococcus granulosus Nuclear hormone receptor family member nhr 41 0.0019 0.0006 0.0002
Echinococcus multilocularis 6 phosphofructokinase 0.012 0.0375 0.0447
Trichomonas vaginalis conserved hypothetical protein 0.0043 0.0094 0.0334
Echinococcus multilocularis aldehyde dehydrogenase, mitochondrial 0.0067 0.0181 0.0213
Schistosoma mansoni sodium/chloride dependent neurotransmitter transporter 0.0038 0.0073 0.0088
Echinococcus multilocularis rhodopsin orphan GPCR 0.0058 0.0146 0.0171
Schistosoma mansoni retinal dehydrogenase 0.0021 0.0013 0.0015
Schistosoma mansoni ancient conserved domain protein 2 (cyclin m2) 0.0058 0.0146 0.0176
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.0021 0.0013 0.0026
Chlamydia trachomatis thioredoxin reductase 0.02 0.0667 0.2323
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0058 0.0146 0.0176
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0019 0.0006 0.0005
Echinococcus multilocularis neuropeptide s receptor 0.0058 0.0146 0.0171
Schistosoma mansoni rab6-interacting 0.0148 0.0478 0.0575
Brugia malayi neuropeptide F receptor 0.0058 0.0146 0.042
Echinococcus multilocularis family S9 non peptidase ue (S09 family) 0.0063 0.0167 0.0196
Loa Loa (eye worm) hypothetical protein 0.0038 0.0073 0.0215
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0047 0.0106 0.0128
Echinococcus granulosus carbonyl reductase 1 0.0021 0.0013 0.0011
Schistosoma mansoni hypothetical protein 0.0058 0.0146 0.0176
Trichomonas vaginalis adenylate cyclase, type VII, putative 0.0042 0.009 0.032
Echinococcus granulosus carbonyl reductase 1 0.0021 0.0013 0.0011
Loa Loa (eye worm) hypothetical protein 0.0058 0.0146 0.043
Loa Loa (eye worm) hypothetical protein 0.0026 0.0032 0.0092
Echinococcus multilocularis thyroid hormone receptor alpha 0.0019 0.0006 0.0002
Entamoeba histolytica glutamate synthase beta subunit, putative 0.02 0.0667 1
Mycobacterium ulcerans cytochrome p450 150 cyp150 0.0042 0.0091 0.0292
Brugia malayi Immunoglobulin I-set domain containing protein 0.003 0.0046 0.0124
Mycobacterium ulcerans cytochrome P450 189A7 Cyp189A7 0.0042 0.0091 0.0292
Schistosoma mansoni short chain dehydrogenase 0.0021 0.0013 0.0015
Echinococcus granulosus sodium and chloride dependent glycine 0.0038 0.0073 0.0083
Trichomonas vaginalis conserved hypothetical protein 0.0042 0.009 0.032
Mycobacterium ulcerans NADPH:adrenodoxin oxidoreductase FprA 0.02 0.0667 0.2443
Leishmania major tyrosyl-DNA phosphodiesterase 1 0.0072 0.0199 0.0186
Echinococcus granulosus alpha 1A adrenergic receptor 0.0058 0.0146 0.0171
Echinococcus granulosus serotonin receptor 0.0058 0.0146 0.0171
Echinococcus granulosus Transcription factor JmjC domain containing protein 0.0168 0.0549 0.0656
Plasmodium falciparum ataxin-2 like protein, putative 0.0054 0.0132 0.0369
Schistosoma mansoni serine/threonine protein kinase 0.0109 0.0333 0.04
Brugia malayi Nuclear hormone receptor family member nhr-3 0.0019 0.0006 0.0005
Loa Loa (eye worm) hypothetical protein 0.0113 0.0349 0.1026
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.2753 1 1
Mycobacterium tuberculosis Possible cytochrome P450 126 Cyp126 0.0042 0.0091 0.0225
Schistosoma mansoni gliotactin 0.0063 0.0167 0.0201
Echinococcus multilocularis pyroglutamylated rfamide peptide receptor 0.0058 0.0146 0.0171
Trichomonas vaginalis PIKK family atypical protein kinase 0.0026 0.0029 0.0094
Schistosoma mansoni opsin-like receptor 0.0058 0.0146 0.0176
Entamoeba histolytica FKBP-rapamycin associated protein (FRAP), putative 0.0047 0.0109 0.1474
Onchocerca volvulus 0.0021 0.0013 0.0027
Echinococcus granulosus arachidonate 5 lipoxygenase 0.0614 0.218 0.2619
Brugia malayi bZIP transcription factor family protein 0.0267 0.0914 0.2685
Wolbachia endosymbiont of Brugia malayi fructose-1,6-bisphosphatase 0.0077 0.0219 0.077
Trichomonas vaginalis PIKK family atypical protein kinase 0.0035 0.0065 0.0226
Toxoplasma gondii Sodium:neurotransmitter symporter family protein 0.0038 0.0073 0.0179
Echinococcus multilocularis netrin receptor unc 5 0.003 0.0046 0.0051
Trichomonas vaginalis chromobox protein, putative 0.0077 0.0218 0.0795
Schistosoma mansoni tar DNA-binding protein 0.0066 0.0177 0.0213
Trichomonas vaginalis PIKK family atypical protein kinase 0.0038 0.0074 0.026
Onchocerca volvulus 0.0058 0.0146 0.0525
Brugia malayi Cytochrome P450 family protein 0.0061 0.016 0.0461
Echinococcus granulosus dihydropyrimidine dehydrogenase NADP 0.02 0.0667 0.0798
Echinococcus multilocularis arachidonate 5 lipoxygenase 0.0614 0.218 0.2619
Leishmania major 3-oxoacyl-(acyl-carrier protein) reductase, putative 0.0195 0.0649 0.0637
Trichomonas vaginalis PIKK family atypical protein kinase 0.0038 0.0074 0.026
Trichomonas vaginalis PIKK family atypical protein kinase 0.0047 0.0109 0.0392
Schistosoma mansoni sodium-dependent amino acid transporter 0.0038 0.0073 0.0088
Trypanosoma cruzi PAB1-binding protein , putative 0.0054 0.0132 0.012
Schistosoma mansoni hypothetical protein 0.0103 0.0312 0.0375
Brugia malayi Doublecortin family protein 0.0148 0.0478 0.1399
Mycobacterium tuberculosis Probable exodeoxyribonuclease III protein XthA (exonuclease III) (EXO III) (AP endonuclease VI) 0.0042 0.0089 0.022
Loa Loa (eye worm) hypothetical protein 0.0148 0.0478 0.1408
Brugia malayi GnHR receptor homolog 0.0058 0.0146 0.042
Schistosoma mansoni steroid dehydrogenase 0.0021 0.0013 0.0015
Schistosoma mansoni biogenic amine (5HT) receptor 0.0058 0.0146 0.0176
Mycobacterium tuberculosis Probable thioredoxin reductase TrxB2 (TRXR) (TR) 0.02 0.0667 0.1885
Plasmodium vivax hypothetical protein, conserved 0.0031 0.0051 0.0112
Trypanosoma brucei apurinic/apyrimidinic endonuclease, putative 0.0042 0.0089 0.0081
Trichomonas vaginalis PIKK family atypical protein kinase 0.0035 0.0065 0.0226
Trypanosoma cruzi STE group serine/threonine-protein kinase, putative 0.0043 0.0094 0.0081
Brugia malayi nuclear hormone receptor 0.0019 0.0006 0.0005
Trichomonas vaginalis glucosylceramidase, putative 0.0188 0.0624 0.231
Brugia malayi hypothetical protein 0.0038 0.0073 0.0205
Trichomonas vaginalis steroid dehydrogenase, putative 0.0021 0.0013 0.0033
Trypanosoma cruzi JmjC domain, hydroxylase, putative 0.0027 0.0036 0.0024
Brugia malayi Nuclear hormone receptor family member nhr-41 0.0019 0.0006 0.0005
Brugia malayi NADPH:adrenodoxin oxidoreductase, mitochondrial precursor 0.02 0.0667 0.1956
Echinococcus granulosus thyrotropin releasing hormone receptor 0.0058 0.0146 0.0171
Echinococcus granulosus hypothetical protein 0.0021 0.0013 0.0011
Mycobacterium ulcerans cytochrome P450 125A7 Cyp125A7 0.0042 0.0091 0.0292
Loa Loa (eye worm) hypothetical protein 0.0198 0.0662 0.1949
Trichomonas vaginalis glucosylceramidase, putative 0.0179 0.0589 0.2179
Entamoeba histolytica pyrophosphate-dependent phosphofructokinase 0.0032 0.0055 0.0639
Echinococcus granulosus neuropeptide Y receptor 0.0058 0.0146 0.0171
Echinococcus granulosus family S9 non peptidase ue S09 family 0.0063 0.0167 0.0196
Mycobacterium ulcerans cytochrome P450 126A3 Cyp126A3 0.0042 0.0091 0.0292
Mycobacterium ulcerans NADPH:adrenodoxin oxidoreductase FprA 0.02 0.0667 0.2443
Leishmania major hypothetical protein, conserved 0.0027 0.0036 0.0024
Trypanosoma brucei short-chain dehydrogenase, putative 0.0021 0.0013 0.0005
Echinococcus granulosus Dehydrogenase:reductase SDR family 0.0021 0.0013 0.0011
Schistosoma mansoni bromodomain-containing nuclear protein 1 brd1 0.0031 0.0051 0.0061
Mycobacterium tuberculosis Probable cytochrome P450 144 Cyp144 0.0042 0.0091 0.0225
Schistosoma mansoni hypothetical protein 0.0037 0.0073 0.0088
Brugia malayi Bloom's syndrome protein homolog 0.0022 0.0017 0.0038
Loa Loa (eye worm) hypothetical protein 0.0058 0.0146 0.043
Brugia malayi O-Glycosyl hydrolase family 30 protein 0.0272 0.0932 0.2738
Trichomonas vaginalis adenylate and guanylate cyclases, putative 0.0042 0.009 0.032
Schistosoma mansoni lamin 0.0056 0.0142 0.0171
Onchocerca volvulus Heterochromatin protein 1 homolog 0.0043 0.0094 0.0329
Trichomonas vaginalis short-chain dehydrogenase, putative 0.0021 0.0013 0.0033
Trichomonas vaginalis PIKK family atypical protein kinase 0.0038 0.0074 0.026
Loa Loa (eye worm) hypothetical protein 0.0056 0.0142 0.0418
Schistosoma mansoni myosin xvIII 0.0058 0.0146 0.0176
Schistosoma mansoni disulfide oxidoreductase 0.02 0.0667 0.0802
Brugia malayi jmjC domain containing protein 0.0027 0.0036 0.0095
Brugia malayi jmjC domain containing protein 0.0027 0.0036 0.0095
Trypanosoma brucei tyrosyl-DNA Phosphodiesterase (Tdp1), putative 0.0072 0.0199 0.0191
Trichomonas vaginalis PIKK family atypical protein kinase 0.0026 0.0029 0.0095
Echinococcus multilocularis jumonji domain containing protein 0.0044 0.0095 0.011
Schistosoma mansoni aldehyde dehydrogenase 0.0067 0.0181 0.0218
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0931 0.3339 0.4015
Trypanosoma brucei NADH dehydrogenase 0.02 0.0667 0.0659
Trichomonas vaginalis PIKK family atypical protein kinase 0.0028 0.0038 0.0128
Mycobacterium ulcerans dihydrolipoamide dehydrogenase 0.0753 0.2689 1
Echinococcus multilocularis Ataxin 2, N terminal,domain containing protein 0.0024 0.0024 0.0024
Loa Loa (eye worm) nuclear Hormone Receptor family member 0.0019 0.0006 0.0015
Mycobacterium leprae PROBABLE NADPH:ADRENODOXIN OXIDOREDUCTASE FPRB (ADRENODOXIN REDUCTASE) (AR) (FERREDOXIN-NADP(+) REDUCTASE) 0.02 0.0667 0.1885
Mycobacterium tuberculosis Probable NADPH dependent 2,4-dienoyl-CoA reductase FadH (2,4-dienoyl coenzyme A reductase) (4-enoyl-CoA reductase) 0.02 0.0667 0.1885
Echinococcus multilocularis 7TM GPCR, rhodopsin 0.0058 0.0146 0.0171
Brugia malayi Uncoordinated protein 44 0.003 0.0046 0.0124
Trichomonas vaginalis CMGC family protein kinase 0.0109 0.0333 0.1224
Mycobacterium tuberculosis Probable cytochrome P450 139 Cyp139 0.0042 0.0091 0.0225
Onchocerca volvulus 0.02 0.0667 0.2462
Echinococcus granulosus rhodopsin orphan GPCR 0.0058 0.0146 0.0171
Schistosoma mansoni transcription factor LCR-F1 0.0037 0.0073 0.0088
Schistosoma mansoni short chain dehydrogenase 0.0021 0.0013 0.0015
Schistosoma mansoni dihydrolipoamide dehydrogenase 0.0753 0.2689 0.3235
Brugia malayi dihydrolipoyl dehydrogenase, mitochondrial precursor, putative 0.0753 0.2689 0.7926
Mycobacterium tuberculosis Probable NADH-dependent glutamate synthase (small subunit) GltD (L-glutamate synthase) (L-glutamate synthetase) (NADH-glutamate 0.02 0.0667 0.1885
Brugia malayi glutamate synthase 0.02 0.0667 0.1956
Mycobacterium ulcerans NADH dehydrogenase 0.02 0.0667 0.2443
Loa Loa (eye worm) hypothetical protein 0.0027 0.0036 0.0103
Trichomonas vaginalis dihydrolipoamide dehydrogenase, putative 0.02 0.0667 0.2467
Leishmania major aldehyde dehydrogenase, mitochondrial precursor 0.0067 0.0181 0.0169
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0047 0.0106 0.0123
Mycobacterium ulcerans short-chain type dehydrogenase/reductase 0.0195 0.0649 0.2376
Loa Loa (eye worm) nuclear hormone receptor family member nhr-40 0.0019 0.0006 0.0015
Echinococcus multilocularis Jumonji, AT rich interactive domain 1B 0.0027 0.0036 0.0039
Brugia malayi Carboxylesterase family protein 0.0063 0.0167 0.048
Trichomonas vaginalis glutamate synthase, putative 0.02 0.0667 0.2467
Mycobacterium tuberculosis POSSIBLE PARA-NITROBENZYL ESTERASE (FRAGMENT) 0.0063 0.0167 0.0444
Echinococcus granulosus thioredoxin glutathione reductase 0.0945 0.3391 0.4078
Mycobacterium ulcerans cytochrome P450 150A6 Cyp150A6 0.0042 0.0091 0.0292
Plasmodium vivax NAD(P)H-dependent glutamate synthase, putative 0.02 0.0667 0.1935
Schistosoma mansoni opsin-like receptor 0.0058 0.0146 0.0176
Echinococcus multilocularis acetylcholinesterase 0.0374 0.1302 0.1563
Mycobacterium ulcerans cytochrome P450 124A1, Cyp124A1 0.0042 0.0091 0.0292
Trypanosoma cruzi mitochondrial DNA polymerase beta, putative 0.0325 0.1123 0.1112
Loa Loa (eye worm) hypothetical protein 0.02 0.0667 0.1964
Loa Loa (eye worm) Sodium:neurotransmitter symporter family protein 0.0038 0.0073 0.0215
Mycobacterium tuberculosis NADPH:adrenodoxin oxidoreductase FprA (NADPH-ferredoxin reductase) 0.02 0.0667 0.1885
Schistosoma mansoni growth hormone secretagogue receptor 0.0058 0.0146 0.0176
Trypanosoma cruzi cytochrome p450-like protein, putative 0.0042 0.0091 0.0078
Loa Loa (eye worm) cytochrome P450 0.0042 0.0091 0.0266
Echinococcus granulosus neuropeptides capa receptor 0.0058 0.0146 0.0171
Trichomonas vaginalis short-chain dehydrogenases/reductase, putative 0.0021 0.0013 0.0033
Schistosoma mansoni aldehyde dehydrogenase 0.0067 0.0181 0.0218
Schistosoma mansoni intermediate filament proteins 0.0056 0.0142 0.0171
Brugia malayi hypothetical protein 0.021 0.0704 0.2066
Trichomonas vaginalis short-chain dehydrogenase, putative 0.0021 0.0013 0.0033
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.0021 0.0013 0.0026
Mycobacterium tuberculosis Probable aldehyde dehydrogenase 0.0067 0.0181 0.0486
Trypanosoma cruzi Present in the outer mitochondrial membrane proteome 4 0.0036 0.0066 0.0054
Leishmania major hypothetical protein, conserved 0.0054 0.0132 0.012
Echinococcus granulosus neuropeptide receptor 0.0058 0.0146 0.0171
Schistosoma mansoni peptide (allatostatin)-like receptor 0.0058 0.0146 0.0176
Loa Loa (eye worm) hypothetical protein 0.0034 0.006 0.0174
Loa Loa (eye worm) programmed cell death 8 0.02 0.0667 0.1964
Echinococcus granulosus NADPH:adrenodoxin oxidoreductase 0.02 0.0667 0.0798
Echinococcus granulosus lipoxygenase domain containing protein 0.0148 0.0478 0.0571
Loa Loa (eye worm) hypothetical protein 0.0058 0.0146 0.043
Trypanosoma brucei short-chain dehydrogenase, putative 0.0021 0.0013 0.0005
Brugia malayi larval opioid receptor 0.0058 0.0146 0.042
Brugia malayi Serotonin receptor 0.0058 0.0146 0.042
Echinococcus multilocularis FAD linked sulfhydryl oxidase ALR 0.0036 0.0066 0.0075
Echinococcus granulosus Polycystic kidney disease protein 0.0148 0.0478 0.0571
Treponema pallidum diphosphate--fructose-6-phosphate 1-phosphotransferase 0.012 0.0375 0.1217
Schistosoma mansoni hypothetical protein 0.0378 0.1317 0.1585
Trichomonas vaginalis spcc417.12 protein, putative 0.0063 0.0167 0.0606
Brugia malayi alpha keto acid dehydrogenase complex, E3 component, lipoamide dehydrogenase 0.0553 0.1958 0.5769
Echinococcus granulosus acetylcholinesterase 0.0374 0.1302 0.1563
Mycobacterium ulcerans exodeoxyribonuclease III protein XthA 0.0042 0.0089 0.0285
Echinococcus granulosus rhodopsin orphan GPCR 0.0058 0.0146 0.0171
Echinococcus granulosus apoptosis inducing factor 1 mitochondrial 0.02 0.0667 0.0798
Toxoplasma gondii PHD-finger domain-containing protein 0.0031 0.0051 0.0112
Echinococcus multilocularis Basic leucine zipper (bZIP) transcription 0.0037 0.0073 0.0083
Loa Loa (eye worm) hypothetical protein 0.0494 0.1743 0.5138
Loa Loa (eye worm) hypothetical protein 0.0058 0.0146 0.043
Trichomonas vaginalis estradiol 17 beta-dehydrogenase, putative 0.0021 0.0013 0.0033
Loa Loa (eye worm) hypothetical protein 0.0054 0.0132 0.0388
Plasmodium falciparum oxidoreductase, short-chain dehydrogenase family, putative 0.0021 0.0013 0.0017
Brugia malayi Death domain containing protein 0.003 0.0046 0.0124
Loa Loa (eye worm) hypothetical protein 0.0374 0.1302 0.3838
Mycobacterium ulcerans aldehyde dehydrogenase 0.0067 0.0181 0.063
Schistosoma mansoni FTZ-F1 nuclear receptor-like protein 0.0019 0.0006 0.0007
Trichomonas vaginalis voltage and ligand gated potassium channel, putative 0.0036 0.0067 0.0234
Mycobacterium tuberculosis Probable cytochrome P450 123 Cyp123 0.0042 0.0091 0.0225
Onchocerca volvulus 0.0021 0.0013 0.0027
Brugia malayi hypothetical protein 0.0058 0.0146 0.042
Onchocerca volvulus 0.0021 0.0013 0.0027
Schistosoma mansoni steroid dehydrogenase 0.0021 0.0013 0.0015
Echinococcus multilocularis musashi 0.0056 0.0142 0.0167
Brugia malayi Dopamine receptor protein 1, putative (partial) 0.0058 0.0146 0.042
Brugia malayi GTP-binding regulatory protein Gs alpha-S chain, putative 0.0047 0.0106 0.0302
Trichomonas vaginalis disulfide oxidoreductase, putative 0.02 0.0667 0.2467
Giardia lamblia Glutamate synthase 0.02 0.0667 0.2443
Echinococcus multilocularis epidermal retinal dehydrogenase 2 0.0021 0.0013 0.0011
Plasmodium falciparum ATP-dependent 6-phosphofructokinase 0.0032 0.0055 0.014
Loa Loa (eye worm) hypothetical protein 0.0058 0.0146 0.043
Brugia malayi Dehydrogenases, short chain protein 2 0.0021 0.0013 0.0026
Schistosoma mansoni cyclic-nucleotide-gated cation channel 0.0019 0.0004 0.0005
Brugia malayi jmjC domain containing protein 0.0103 0.0312 0.091
Echinococcus granulosus peregrin 0.0031 0.0051 0.0056
Loa Loa (eye worm) hypothetical protein 0.0019 0.0006 0.0015
Echinococcus multilocularis rhodopsin orphan GPCR 0.0058 0.0146 0.0171
Loa Loa (eye worm) oxidoreductase 0.0021 0.0013 0.0036
Echinococcus granulosus histone lysine methyltransferase setb 0.0095 0.0283 0.0336
Echinococcus granulosus 5'partial|histone lysine N methyltransferase SETDB2 0.0091 0.027 0.032
Loa Loa (eye worm) hypothetical protein 0.0019 0.0006 0.0015
Trichomonas vaginalis short-chain dehydrogenase, putative 0.0021 0.0013 0.0033
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0047 0.0106 0.0123
Toxoplasma gondii pyridine nucleotide-disulfide oxidoreductase domain-containing protein 0.02 0.0667 0.1935
Giardia lamblia Thioredoxin reductase 0.02 0.0667 0.2443
Schistosoma mansoni hypothetical protein 0.0058 0.0146 0.0176
Onchocerca volvulus 0.0058 0.0146 0.0525
Mycobacterium tuberculosis Probable membrane NADH dehydrogenase NdhA 0.0417 0.1459 0.417
Mycobacterium tuberculosis Probable short-chain type dehydrogenase/reductase 0.0195 0.0649 0.1833
Echinococcus granulosus chromobox protein 1 0.0077 0.0218 0.0257
Schistosoma mansoni short chain dehydrogenase 0.0021 0.0013 0.0015
Echinococcus granulosus 6 phosphofructokinase 0.012 0.0375 0.0447
Plasmodium falciparum glutathione reductase 0.0753 0.2689 0.7924
Schistosoma mansoni hypothetical protein 0.0036 0.0067 0.008
Mycobacterium ulcerans cytochrome P450 143A4 Cyp143A4 0.0042 0.0091 0.0292
Echinococcus granulosus fmrfamide receptor 0.0058 0.0146 0.0171
Schistosoma mansoni ataxia telangiectasia mutated (atm)-related 0.0047 0.0109 0.0131
Echinococcus multilocularis chromobox protein 1 0.0077 0.0218 0.0257
Loa Loa (eye worm) 6-phosphofructokinase 0.012 0.0375 0.1105
Trypanosoma cruzi pyridine nucleotide-disulphide oxidoreductase, putative 0.02 0.0667 0.0655
Echinococcus multilocularis 3 hydroxyacyl coenzyme A dehydrogenase type 2 0.0195 0.0649 0.0776
Echinococcus granulosus serotonin transporter 0.0221 0.0746 0.0893
Mycobacterium tuberculosis Probable cytochrome P450 125 Cyp125 0.0042 0.0091 0.0225
Schistosoma mansoni amine GPCR 0.0058 0.0146 0.0176
Loa Loa (eye worm) hypothetical protein 0.0019 0.0006 0.0015
Plasmodium falciparum type II NADH:ubiquinone oxidoreductase 0.02 0.0667 0.1949
Plasmodium vivax dihydrolipoyl dehydrogenase, mitochondrial, putative 0.0753 0.2689 0.7921
Echinococcus multilocularis sodium channel protein 0.0125 0.0391 0.0466
Echinococcus multilocularis orexin receptor type 2 0.0058 0.0146 0.0171
Loa Loa (eye worm) heterochromatin protein 1 0.0077 0.0218 0.064
Brugia malayi Pre-SET motif family protein 0.0662 0.2355 0.6941
Wolbachia endosymbiont of Brugia malayi exonuclease III 0.0042 0.0089 0.0285
Echinococcus granulosus JmjC domain containing protein 4 0.0027 0.0036 0.0039
Mycobacterium ulcerans cytochrome P450 143A3 Cyp143A3 0.0042 0.0091 0.0292
Schistosoma mansoni neuropeptide f receptor 76f 0.0058 0.0146 0.0176
Loa Loa (eye worm) GTP-binding regulatory protein Gs alpha-S chain 0.0047 0.0106 0.0312
Brugia malayi ERG2 and Sigma1 receptor like protein 0.0388 0.1356 0.399
Trypanosoma cruzi mitochondrial DNA polymerase beta-PAK, putative 0.0046 0.0103 0.009
Echinococcus granulosus neuropeptide Y receptor 0.0058 0.0146 0.0171
Loa Loa (eye worm) hypothetical protein 0.0019 0.0006 0.0015
Loa Loa (eye worm) hypothetical protein 0.0021 0.0013 0.0036
Echinococcus multilocularis transfer RNA-Lys 0.012 0.0375 0.0446
Echinococcus granulosus jun protein 0.0267 0.0914 0.1095
Echinococcus multilocularis alpha 1A adrenergic receptor 0.0058 0.0146 0.0171
Onchocerca volvulus 0.012 0.0375 0.1376
Echinococcus granulosus Basic leucine zipper bZIP transcription factor 0.0267 0.0914 0.1095
Brugia malayi Dopamine receptor protein 2 0.0058 0.0146 0.042
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0058 0.0146 0.0176
Loa Loa (eye worm) hypothetical protein 0.0063 0.0167 0.049
Echinococcus multilocularis carbonyl reductase 1 0.0021 0.0013 0.0011
Trypanosoma cruzi hypothetical protein, conserved 0.02 0.0667 0.0655
Echinococcus granulosus hepatocyte nuclear factor 4 alpha 0.0019 0.0006 0.0002
Trichomonas vaginalis PIKK family atypical protein kinase 0.0035 0.0065 0.0226
Entamoeba histolytica thioredoxin reductase, putative 0.02 0.0667 1
Schistosoma mansoni steroid hormone receptor ad4bp 0.0019 0.0006 0.0007
Brugia malayi Cytochrome P450 family protein 0.0042 0.0091 0.0257
Schistosoma mansoni amine GPCR 0.0582 0.2062 0.2481
Plasmodium falciparum phd finger protein, putative 0.0031 0.0051 0.0128
Trypanosoma brucei mitogen activated protein kinase 4, putative 0.0109 0.0333 0.0325
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0058 0.0146 0.0176
Trichomonas vaginalis CMGC family protein kinase 0.0109 0.0333 0.1224
Loa Loa (eye worm) Sodium:neurotransmitter symporter family protein 0.0038 0.0073 0.0215
Trypanosoma cruzi pyridine nucleotide-disulphide oxidoreductase, putative 0.02 0.0667 0.0655
Loa Loa (eye worm) hypoxia-induced factor 1 0.0502 0.1771 0.5223
Plasmodium falciparum thioredoxin reductase 0.0753 0.2689 0.7924
Onchocerca volvulus Dehydrogenase\/reductase SDR family member 1 homolog 0.0021 0.0013 0.0027
Schistosoma mansoni biogenic amine receptor 0.0058 0.0146 0.0176
Onchocerca volvulus Dehydrogenase\/reductase SDR family member 13 homolog 0.0021 0.0013 0.0027
Echinococcus multilocularis FTZ F1 alpha 0.0019 0.0006 0.0002
Loa Loa (eye worm) hypothetical protein 0.0494 0.1743 0.5138
Schistosoma mansoni steroid dehydrogenase 0.0021 0.0013 0.0015
Mycobacterium ulcerans NADH dehydrogenase Ndh1 0.02 0.0667 0.2443
Trypanosoma brucei cytochrome P450, putative 0.0061 0.016 0.0152
Plasmodium vivax SET domain protein, putative 0.0095 0.0283 0.08
Treponema pallidum oxidoreductase 0.02 0.0667 0.2323
Echinococcus multilocularis chromobox protein 1 0.0077 0.0218 0.0257
Loa Loa (eye worm) hypothetical protein 0.0063 0.0167 0.049
Brugia malayi jmjC domain containing protein 0.0027 0.0036 0.0095
Onchocerca volvulus 0.0056 0.0142 0.051
Trichomonas vaginalis mercuric reductase, putative 0.0753 0.2689 0.9998
Treponema pallidum sodium- and chloride- dependent transporter 0.0221 0.0746 0.2623
Echinococcus granulosus FTZ F1 nuclear receptor protein 0.0019 0.0006 0.0002
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.0021 0.0013 0.0026
Loa Loa (eye worm) hypothetical protein 0.0058 0.0146 0.043
Mycobacterium ulcerans dihydrolipoamide dehydrogenase, LpdB 0.0753 0.2689 1
Loa Loa (eye worm) hypothetical protein 0.0055 0.0139 0.0407
Echinococcus granulosus g-protein coupled receptor 0.0058 0.0146 0.0171
Brugia malayi Melatonin receptor type 1A 0.0058 0.0146 0.042
Echinococcus granulosus cadherin EGF LAG seven pass G type receptor 0.0036 0.0067 0.0075
Trypanosoma brucei 3-keto-dihydrosphingosine reductase 0.0021 0.0013 0.0005
Brugia malayi hypothetical protein 0.0504 0.1777 0.5236
Brugia malayi hypothetical protein 0.0021 0.0013 0.0026
Trypanosoma brucei target of rapamycin kinase 3, putative 0.0038 0.0074 0.0066
Giardia lamblia Kinase, CMGC MAPK 0.0109 0.0333 0.1196
Onchocerca volvulus 0.0042 0.009 0.0315
Brugia malayi PAS domain containing protein 0.0162 0.0529 0.155
Entamoeba histolytica myo-inositol monophosphatase, putative 0.0077 0.0219 0.315
Trypanosoma cruzi cytochrome P450, putative 0.0061 0.016 0.0147
Schistosoma mansoni short chain dehydrogenase 0.0021 0.0013 0.0015
Brugia malayi Dopamine receptor 0.0058 0.0146 0.042
Brugia malayi hypothetical protein 0.0021 0.0013 0.0026
Mycobacterium ulcerans extragenic suppressor protein SuhB 0.0077 0.0219 0.077
Treponema pallidum exodeoxyribonuclease (exoA) 0.0042 0.0089 0.0131
Onchocerca volvulus 0.0148 0.0478 0.176
Echinococcus multilocularis steroid dehydrogenase 0.0021 0.0013 0.0011
Trichomonas vaginalis PIKK family atypical protein kinase 0.0035 0.0065 0.0226
Brugia malayi hypothetical protein 0.0058 0.0146 0.042
Echinococcus multilocularis rhodopsin orphan GPCR 0.0058 0.0146 0.0171
Brugia malayi Cytochrome P450 family protein 0.0061 0.016 0.0461
Brugia malayi hypothetical protein 0.0058 0.0146 0.042
Schistosoma mansoni hypothetical protein 0.0031 0.0051 0.0061
Trypanosoma brucei protein kinase, putative 0.0109 0.0333 0.0325
Schistosoma mansoni adenoreceptor 0.0058 0.0146 0.0176
Echinococcus granulosus 3 hydroxyacyl coenzyme A dehydrogenase type 2 0.0195 0.0649 0.0776
Schistosoma mansoni biogenic amine (5HT) receptor 0.0311 0.1073 0.1292
Schistosoma mansoni hypothetical protein 0.0042 0.0091 0.0109
Toxoplasma gondii thioredoxin reductase 0.0945 0.3391 1
Mycobacterium ulcerans putative regulatory protein 0.012 0.0375 0.1353
Plasmodium falciparum LCCL domain-containing protein 0.0148 0.0478 0.1391
Brugia malayi MAP kinase sur-1 0.0109 0.0333 0.097
Echinococcus granulosus G protein coupled 5 hydroxytryptamine receptor 0.0058 0.0146 0.0171
Loa Loa (eye worm) intermediate filament tail domain-containing protein 0.0056 0.0142 0.0418
Schistosoma mansoni short chain dehydrogenase 0.0021 0.0013 0.0015
Trypanosoma cruzi JmjC domain, hydroxylase, putative 0.0027 0.0036 0.0024
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.0021 0.0013 0.0026
Loa Loa (eye worm) carboxylesterase 0.0374 0.1302 0.3838
Loa Loa (eye worm) unidentified vitellogenin-linked transcript protein 6 0.0058 0.0146 0.043
Trypanosoma cruzi DNA polymerase beta thumb, putative 0.0046 0.0103 0.009
Schistosoma mansoni 3-keto-dihydrosphingosine reductase 0.0021 0.0013 0.0015
Trichomonas vaginalis PIKK family atypical protein kinase 0.0028 0.0039 0.0132
Chlamydia trachomatis Ssodium-dependent amino acid transporter 0.0038 0.0073 0.0071
Echinococcus multilocularis RUN 0.0148 0.0478 0.0571
Entamoeba histolytica hypothetical protein 0.0037 0.0073 0.0916
Echinococcus granulosus dro:myosuppressin receptor 0.0058 0.0146 0.0171
Brugia malayi ORL1-like opioid receptor 0.0058 0.0146 0.042
Brugia malayi Unidentified vitellogenin-linked transcript protein 6, putative 0.0058 0.0146 0.042
Echinococcus multilocularis microtubule associated protein 2 0.2291 0.831 1
Echinococcus granulosus allatostatin A receptor 0.0058 0.0146 0.0171
Mycobacterium tuberculosis Probable nitrite reductase [NAD(P)H] large subunit [FAD flavoprotein] NirB 0.0417 0.1459 0.417
Echinococcus multilocularis survival motor neuron protein 1 0.0504 0.1777 0.2135
Trichomonas vaginalis PIKK family atypical protein kinase 0.0047 0.0109 0.0392
Loa Loa (eye worm) hypothetical protein 0.0058 0.0146 0.043
Toxoplasma gondii hypothetical protein 0.0038 0.0073 0.0179
Toxoplasma gondii CMGC kinase, MAPK family (ERK) MAPK-1 0.0109 0.0333 0.0947
Onchocerca volvulus 0.0056 0.0142 0.051
Mycobacterium ulcerans cytochrome P450 188A3 Cyp188A3 0.0042 0.0091 0.0292
Schistosoma mansoni hypothetical protein 0.0036 0.0067 0.008
Brugia malayi hypothetical protein 0.0058 0.0146 0.042
Trichomonas vaginalis phosphofructokinase, putative 0.012 0.0375 0.1382
Echinococcus multilocularis transient receptor potential cation channel 0.0021 0.0013 0.0011
Schistosoma mansoni steroid dehydrogenase 0.0021 0.0013 0.0015
Mycobacterium tuberculosis Probable cytochrome P450 138 Cyp138 0.0042 0.0091 0.0225
Mycobacterium tuberculosis Inositol-1-monophosphatase SuhB 0.0069 0.0189 0.0508
Onchocerca volvulus 0.0058 0.0146 0.0525
Echinococcus granulosus neuropeptides capa receptor 0.0058 0.0146 0.0171
Loa Loa (eye worm) gonadotropin-releasing hormone receptor 2 0.0058 0.0146 0.043
Echinococcus multilocularis lysine specific demethylase 5A 0.0103 0.0312 0.0371
Loa Loa (eye worm) hypothetical protein 0.0058 0.0146 0.043
Schistosoma mansoni muscarinic acetylcholine (GAR) receptor 0.0058 0.0146 0.0176
Schistosoma mansoni hyperpolarization activated cyclic nucleotide-gated potassium channel 0.0019 0.0004 0.0005
Echinococcus multilocularis g protein linked acetylcholine receptor gar 2a 0.0058 0.0146 0.0171
Mycobacterium tuberculosis Cytochrome P450 51 Cyp51 (CYPL1) (P450-L1A1) (sterol 14-alpha demethylase) (lanosterol 14-alpha demethylase) (P450-14DM) 0.0185 0.0613 0.1731
Brugia malayi Carboxylesterase family protein 0.0063 0.0167 0.048
Loa Loa (eye worm) CMGC/MAPK/ERK1 protein kinase 0.0109 0.0333 0.098
Entamoeba histolytica exodeoxyribonuclease III, putative 0.0042 0.0089 0.1168
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0095 0.0283 0.034
Brugia malayi Pyridine nucleotide-disulphide oxidoreductase family protein 0.02 0.0667 0.1956
Echinococcus multilocularis cadherin EGF LAG seven pass G type receptor 0.0036 0.0067 0.0075
Loa Loa (eye worm) 3-hydroxyacyl-CoA dehydrogenase type II 0.0174 0.0572 0.1684
Schistosoma mansoni lamin 0.0056 0.0142 0.0171
Echinococcus multilocularis COUP TF:Svp nuclear hormone receptor 0.0019 0.0006 0.0002
Echinococcus multilocularis g protein coupled receptor 0.0058 0.0146 0.0171
Schistosoma mansoni steroid dehydrogenase 0.0021 0.0013 0.0015
Schistosoma mansoni rab6-interacting 0.0148 0.0478 0.0575
Loa Loa (eye worm) hypothetical protein 0.0021 0.0013 0.0036
Echinococcus granulosus sodium dependent neurotransmitter transporter 0.0038 0.0073 0.0083
Echinococcus multilocularis potassium voltage gated channel subfamily H 0.0049 0.0117 0.0135
Echinococcus granulosus sulfide:quinone oxidoreductase 0.02 0.0667 0.0798
Brugia malayi Carboxylesterase family protein 0.0374 0.1302 0.3832
Trichomonas vaginalis PIKK family atypical protein kinase 0.0026 0.0029 0.0094
Echinococcus granulosus rhodopsin orphan GPCR 0.0058 0.0146 0.0171
Schistosoma mansoni short chain dehydrogenase 0.0021 0.0013 0.0015
Toxoplasma gondii histone lysine demethylase JMJD6a 0.0027 0.0036 0.007
Mycobacterium ulcerans cytochrome P450 142A3 Cyp142A3 0.0042 0.0091 0.0292
Loa Loa (eye worm) hypothetical protein 0.0058 0.0146 0.043
Trypanosoma cruzi hypothetical protein, conserved 0.02 0.0667 0.0655
Toxoplasma gondii pyridine nucleotide-disulfide oxidoreductase domain-containing protein 0.02 0.0667 0.1935
Trichomonas vaginalis glucosylceramidase, putative 0.0179 0.0589 0.2179
Echinococcus granulosus PHD finger protein rhinoceros 0.0031 0.0051 0.0056
Mycobacterium ulcerans cytochrome P450 136A2 Cyp136A2 0.0042 0.0091 0.0292
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0058 0.0146 0.0176
Entamoeba histolytica hypothetical protein 0.0037 0.0073 0.0916
Brugia malayi glutathione reductase 0.0945 0.3391 1
Loa Loa (eye worm) CYP4Cod1 0.0061 0.016 0.047
Brugia malayi Protein kinase domain containing protein 0.0031 0.005 0.0134
Loa Loa (eye worm) aryl Hydrocarbon receptor Associated protein family member 0.0042 0.009 0.0264
Loa Loa (eye worm) TAR-binding protein 0.0066 0.0177 0.0519
Trypanosoma cruzi cytochrome P450, putative 0.0061 0.016 0.0147
Loa Loa (eye worm) hypothetical protein 0.0058 0.0146 0.043
Trypanosoma cruzi NADH dehydrogenase, putative 0.02 0.0667 0.0655
Echinococcus granulosus lysine specific demethylase 6a 0.0027 0.0036 0.0039
Echinococcus multilocularis BC026374 protein (S09 family) 0.0063 0.0167 0.0196
Echinococcus multilocularis Basic leucine zipper (bZIP) transcription factor 0.0267 0.0914 0.1095
Echinococcus multilocularis carbonyl reductase 1 0.0021 0.0013 0.0011
Trypanosoma cruzi Phosphatidylinositol 3-kinase tor2 0.0047 0.0109 0.0096
Schistosoma mansoni peptide (FMRFamide/somatostatin)-like receptor 0.0058 0.0146 0.0176
Toxoplasma gondii non-proton pumping type-II NADH dehydrogenase I 0.02 0.0667 0.1935
Echinococcus granulosus somatostatin receptor 0.0058 0.0146 0.0171
Trypanosoma brucei dihydrolipoamide dehydrogenase 0.2313 0.8392 0.839
Echinococcus multilocularis lipoxygenase domain containing protein 0.0148 0.0478 0.0571
Onchocerca volvulus 0.0148 0.0478 0.176
Trichomonas vaginalis dihydropyrimidine dehydrogenase, putative 0.02 0.0667 0.2467
Brugia malayi Sodium:neurotransmitter symporter family protein 1, putative 0.0038 0.0073 0.0205
Trichomonas vaginalis adenylate cyclase, putative 0.0042 0.009 0.032
Loa Loa (eye worm) pre-SET domain-containing protein family protein 0.0662 0.2355 0.6944
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0019 0.0006 0.0005
Mycobacterium ulcerans cytochrome P450 108B4 Cyp108B4 0.0042 0.0091 0.0292
Echinococcus granulosus diuretic hormone 44 receptor GPRdih2 0.0036 0.0067 0.0075
Brugia malayi calcium-independent alpha-latrotoxin receptor 2, putative 0.0036 0.0067 0.0184
Echinococcus multilocularis bloom syndrome protein 0.0022 0.0017 0.0016
Entamoeba histolytica phosphatidylinositol3-kinaseTor2, putative 0.0047 0.0109 0.1474
Echinococcus granulosus retinol dehydrogenase 11 0.0021 0.0013 0.0011
Loa Loa (eye worm) hypothetical protein 0.0038 0.0073 0.0215
Brugia malayi Sodium:neurotransmitter symporter family protein 0.0038 0.0073 0.0205
Brugia malayi Hypothetical oxidoreductase F56D1.5 0.0021 0.0013 0.0026
Schistosoma mansoni carbonyl reductase 0.0021 0.0013 0.0015
Loa Loa (eye worm) hypothetical protein 0.0058 0.0146 0.043
Echinococcus granulosus lamin 0.0056 0.0142 0.0167
Brugia malayi Nuclear hormone receptor family member nhr-40 0.0019 0.0006 0.0005
Echinococcus multilocularis rhodopsin orphan GPCR 0.0058 0.0146 0.0171
Onchocerca volvulus Heterochromatin protein 1 homolog 0.0046 0.0106 0.0373
Trichomonas vaginalis PIKK family atypical protein kinase 0.0031 0.0048 0.0165
Echinococcus multilocularis G-protein coupled receptor, putative 0.0058 0.0146 0.0171
Schistosoma mansoni histamine h1 receptor 0.0058 0.0146 0.0176
Brugia malayi hypothetical protein 0.0058 0.0146 0.042
Onchocerca volvulus 0.0058 0.0146 0.0525
Toxoplasma gondii selenide, water dikinase 0.02 0.0667 0.1935
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0095 0.0283 0.034
Mycobacterium tuberculosis Probable dehydrogenase 0.0417 0.1459 0.417
Schistosoma mansoni lipoxygenase 0.0347 0.1204 0.1449
Loa Loa (eye worm) hypothetical protein 0.0026 0.0032 0.0092
Leishmania major calcium channel protein, putative,ion transporter, putative 0.0125 0.0391 0.0379
Plasmodium vivax JmjC domain containing protein 0.0027 0.0036 0.007
Mycobacterium tuberculosis Probable cytochrome P450 141 Cyp141 0.0042 0.0091 0.0225
Entamoeba histolytica hypothetical protein 0.0037 0.0073 0.0916
Loa Loa (eye worm) hypothetical protein 0.0058 0.0146 0.043
Trypanosoma cruzi NADPH:adrenodoxin oxidoreductase, mitochondrial, putative 0.02 0.0667 0.0655
Brugia malayi Nuclear hormone receptor family member nhr-31 0.0019 0.0006 0.0005
Loa Loa (eye worm) hypothetical protein 0.0058 0.0146 0.043
Trypanosoma cruzi trypanothione reductase, putative 0.0945 0.3391 0.3383
Brugia malayi Tachykinin-like peptides receptor 99D 0.0058 0.0146 0.042
Loa Loa (eye worm) hypothetical protein 0.0058 0.0146 0.043
Leishmania major NADH dehydrogenase, putative 0.02 0.0667 0.0655
Brugia malayi hypothetical protein 0.0148 0.0478 0.1399
Brugia malayi RNA binding protein 0.0066 0.0177 0.051
Loa Loa (eye worm) latrophilin receptor protein 2 0.0036 0.0067 0.0194
Echinococcus multilocularis sex peptide receptor 0.0058 0.0146 0.0171
Trypanosoma brucei mitochondrial DNA polymerase beta-PAK 0.0154 0.0498 0.049
Trypanosoma cruzi NADH dehydrogenase, putative 0.02 0.0667 0.0655
Trichomonas vaginalis phosphofructokinase, putative 0.0032 0.0055 0.0188
Plasmodium falciparum thioredoxin reductase 0.0945 0.3391 1
Trichomonas vaginalis phosphofructokinase, putative 0.0032 0.0055 0.0188
Mycobacterium ulcerans aldehyde dehydrogenase 0.0067 0.0181 0.063
Trypanosoma cruzi ATP-dependent 6-phosphofructokinase, glycosomal 0.012 0.0375 0.0363
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.2018 0.7315 0.7312
Trichomonas vaginalis phosphofructokinase, putative 0.0032 0.0055 0.0188
Toxoplasma gondii 6-phosphofructokinase 0.0032 0.0055 0.0124
Echinococcus granulosus growth hormone secretagogue receptor type 1 0.0058 0.0146 0.0171
Echinococcus multilocularis hepatocyte nuclear factor 4 alpha 0.0019 0.0006 0.0002
Schistosoma mansoni chromobox protein 0.0077 0.0218 0.0262
Echinococcus granulosus bloom syndrome protein 0.0022 0.0017 0.0016
Entamoeba histolytica dihydropyrimidine dehydrogenase, putative 0.02 0.0667 1
Giardia lamblia Pyrophosphate-fructose 6-phosphate 1-phosphotransferase alpha subunit 0.0032 0.0055 0.0156
Leishmania major cytochrome p450-like protein 0.0042 0.0091 0.0078
Echinococcus multilocularis peptide (allatostatin:somatostatin) 0.0058 0.0146 0.0171
Leishmania major hypothetical protein, conserved 0.02 0.0667 0.0655
Loa Loa (eye worm) hypothetical protein 0.0038 0.0073 0.0215
Schistosoma mansoni glutamate synthase 0.02 0.0667 0.0802
Loa Loa (eye worm) RecQ helicase 0.0022 0.0017 0.0048
Echinococcus multilocularis fmrfamide receptor 0.0058 0.0146 0.0171
Onchocerca volvulus 0.0058 0.0146 0.0525
Loa Loa (eye worm) melatonin receptor type 1A 0.0058 0.0146 0.043
Trypanosoma brucei short-chain dehydrogenase, putative 0.0021 0.0013 0.0005
Echinococcus granulosus FAD linked sulfhydryl oxidase ALR 0.0036 0.0066 0.0075
Leishmania major mitochondrial DNA polymerase beta 0.0325 0.1123 0.1112
Brugia malayi hypothetical protein 0.0058 0.0146 0.042
Echinococcus granulosus para nitrobenzyl esterase 0.0063 0.0167 0.0196
Plasmodium falciparum steroid dehydrogenase, putative 0.0021 0.0013 0.0017
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0047 0.0106 0.0128
Loa Loa (eye worm) dehydrogenase 0.0021 0.0013 0.0036
Loa Loa (eye worm) hypothetical protein 0.0019 0.0006 0.0015
Echinococcus granulosus lamin dm0 0.0056 0.0142 0.0167
Trypanosoma brucei phosphatidylinositol 3-kinase tor, putative 0.0022 0.0018 0.001
Trichomonas vaginalis disulfide oxidoreductase, putative 0.02 0.0667 0.2467
Toxoplasma gondii exonuclease III APE 0.0042 0.0089 0.0226
Trypanosoma cruzi myo-inositol-1(or 4)-monophosphatase 1, putative 0.0077 0.0219 0.0206
Trichomonas vaginalis conserved hypothetical protein 0.0042 0.009 0.032
Trypanosoma cruzi STE group serine/threonine-protein kinase, putative 0.0043 0.0094 0.0081
Mycobacterium tuberculosis Cytochrome P450 121 Cyp121 0.0042 0.0091 0.0225
Loa Loa (eye worm) steroid hormone receptor 0.0019 0.0006 0.0015
Mycobacterium ulcerans cytochrome P450 187A5 Cyp187A5 0.0042 0.0091 0.0292
Trichomonas vaginalis dihydroorotate dehydrogenase, putative 0.02 0.0667 0.2467
Onchocerca volvulus 0.0021 0.0013 0.0027
Echinococcus multilocularis serotonin transporter 0.0221 0.0746 0.0893
Echinococcus multilocularis uncharacterized sodium dependent transporter 0.0038 0.0073 0.0083
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0058 0.0146 0.0176
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0019 0.0006 0.0002
Schistosoma mansoni peptide (FMRFamide/neurokinin-3)-like receptor 0.0058 0.0146 0.0176
Schistosoma mansoni thyrotropin-releasing hormone receptor 0.0058 0.0146 0.0176
Mycobacterium ulcerans cytochrome P450 140A5 Cyp140A5 0.0042 0.0091 0.0292
Schistosoma mansoni thyroid hormone receptor 0.0019 0.0006 0.0007
Entamoeba histolytica glutamate synthase beta subunit, putative 0.02 0.0667 1
Mycobacterium tuberculosis Putative ferredoxin reductase 0.0417 0.1459 0.417
Echinococcus granulosus retinoic acid receptor rxr beta a 0.0019 0.0006 0.0002
Echinococcus granulosus tar DNA binding protein 0.0066 0.0177 0.0208
Schistosoma mansoni voltage-gated potassium channel 0.0053 0.0129 0.0156
Schistosoma mansoni hypothetical protein 0.003 0.0046 0.0055
Schistosoma mansoni ap endonuclease 0.0042 0.0089 0.0107
Echinococcus granulosus jumonji domain containing 1A 0.0027 0.0036 0.0039
Trypanosoma brucei beta-ketoacyl-ACP reductase 2 0.0021 0.0013 0.0005
Echinococcus granulosus voltage gated sodium channel Nav1 alpha subunit 0.0125 0.0391 0.0466
Mycobacterium leprae THIOREDOXIN TRXC (TRX) (MPT46) 0.02 0.0667 0.1885
Echinococcus granulosus ankyrin repeat and death domain containing protein 0.003 0.0046 0.0051
Trypanosoma brucei PAB1-binding protein , putative 0.0054 0.0132 0.0124
Brugia malayi hypothetical protein 0.0035 0.0063 0.0173
Trichomonas vaginalis glucosylceramidase, putative 0.0179 0.0589 0.2179
Leishmania major target of rapamycin (TOR) kinase 2, putative 0.0047 0.0109 0.0096
Trichomonas vaginalis phosphofructokinase, putative 0.012 0.0375 0.1382
Leishmania major apurinic/apyrimidinic endonuclease-redox protein 0.0042 0.0089 0.0076
Trichomonas vaginalis glucosylceramidase, putative 0.0272 0.0932 0.3454
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0058 0.0146 0.0171
Entamoeba histolytica tyrosyl-DNA phosphodiesterase, putative 0.0072 0.0199 0.2848
Leishmania major PAS-domain containing phosphoglycerate kinase, putative 0.0042 0.009 0.0077
Toxoplasma gondii pyridine nucleotide-disulfide oxidoreductase domain-containing protein 0.02 0.0667 0.1935
Echinococcus multilocularis somatostatin receptor 0.0058 0.0146 0.0171
Plasmodium falciparum amino acid transporter, putative 0.0038 0.0073 0.0196
Echinococcus granulosus tm gpcr rhodopsin 0.0058 0.0146 0.0171
Plasmodium vivax 6-phosphofructokinase, putative 0.0032 0.0055 0.0124
Loa Loa (eye worm) hypothetical protein 0.0058 0.0146 0.043
Onchocerca volvulus Neuropeptide F receptor homolog 0.0058 0.0146 0.0525
Leishmania major C-8 sterol isomerase-like protein 0.0388 0.1356 0.1344
Echinococcus granulosus hypothetical protein 0.0021 0.0013 0.0011
Trypanosoma brucei pyridine nucleotide-disulphide oxidoreductase, putative 0.02 0.0667 0.0659
Schistosoma mansoni inositol monophosphatase 0.0077 0.0219 0.0263
Loa Loa (eye worm) hypothetical protein 0.0544 0.1926 0.5678
Brugia malayi hypothetical protein 0.0135 0.0428 0.1251
Echinococcus granulosus nuclear factor of activated T cells 5 0.0154 0.05 0.0597
Schistosoma mansoni opsin-like receptor 0.0058 0.0146 0.0176
Loa Loa (eye worm) tyrosyl-DNA phosphodiesterase 0.0072 0.0199 0.0585
Toxoplasma gondii histone lysine methyltransferase SET/SUV39 0.0095 0.0283 0.08
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.2313 0.8392 0.839
Onchocerca volvulus 0.0021 0.0013 0.0027
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.0021 0.0013 0.0026
Onchocerca volvulus 0.0021 0.0013 0.0027
Trichomonas vaginalis apoptosis inducing factor, putative 0.02 0.0667 0.2467
Brugia malayi dehydrogenases, short chain protein 2 0.0021 0.0013 0.0026
Echinococcus multilocularis neuropeptide receptor 0.0058 0.0146 0.0171
Brugia malayi Phosphatidylinositol 3- and 4-kinase family protein 0.0047 0.0109 0.031
Trichomonas vaginalis adenylate and guanylate cyclases, putative 0.0042 0.009 0.032
Brugia malayi Bromodomain containing protein 0.0031 0.0051 0.0137
Trypanosoma cruzi Phosphatidylinositol 3-kinase tor1 0.0047 0.0109 0.0096
Brugia malayi Carboxylesterase family protein 0.0063 0.0167 0.048
Schistosoma mansoni ankyrin 23/unc44 0.003 0.0046 0.0055
Trichomonas vaginalis adenylate and guanylate cyclases, putative 0.0042 0.009 0.032
Trichomonas vaginalis short-chain dehydrogenase, putative 0.0021 0.0013 0.0033
Trichomonas vaginalis glucosylceramidase, putative 0.0188 0.0624 0.231
Mycobacterium leprae PROBABLE 6-PHOSPHOFRUCTOKINASE PFKA (PHOSPHOHEXOKINASE) (PHOSPHOFRUCTOKINASE) 0.012 0.0375 0.1045
Echinococcus multilocularis tyrosyl DNA phosphodiesterase 1 0.0072 0.0199 0.0235
Loa Loa (eye worm) jmjC domain-containing protein 0.0103 0.0312 0.0919
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.0021 0.0013 0.0026
Trichomonas vaginalis myo inositol monophosphatase, putative 0.0077 0.0219 0.08
Brugia malayi Tyrosyl-DNA phosphodiesterase family protein 0.0072 0.0199 0.0576
Echinococcus granulosus g protein linked acetylcholine receptor gar 2a 0.0058 0.0146 0.0171
Trypanosoma brucei mitochondrial DNA polymerase beta 0.0325 0.1123 0.1116
Onchocerca volvulus 0.0063 0.0167 0.06
Echinococcus multilocularis aryl hydrocarbon receptor 0.0042 0.009 0.0104
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0058 0.0146 0.0171
Echinococcus multilocularis transcription factor Dp 1 0.0042 0.0088 0.0101
Schistosoma mansoni hypothetical protein 0.0058 0.0146 0.0176
Brugia malayi steroid hormone receptor 0.0019 0.0006 0.0005
Onchocerca volvulus 0.0021 0.0013 0.0027
Trichomonas vaginalis soluble guanylate cyclase gcy, putative 0.0042 0.009 0.032
Schistosoma mansoni sodium/chloride dependent transporter 0.0039 0.0077 0.0093
Mycobacterium ulcerans flavoprotein disulfide reductase 0.0753 0.2689 1
Trichomonas vaginalis phosphofructokinase, putative 0.0032 0.0055 0.0188
Plasmodium vivax 6-phosphofructokinase, putative 0.0032 0.0055 0.0124
Loa Loa (eye worm) voltage and ligand gated potassium channel 0.0049 0.0117 0.0342
Echinococcus multilocularis histone lysine methyltransferase setb histone lysine methyltransferase eggless 0.0095 0.0283 0.0336
Plasmodium falciparum dihydrolipoyl dehydrogenase, apicoplast 0.0753 0.2689 0.7924
Brugia malayi Heterochromatin protein 1 0.0077 0.0218 0.063
Loa Loa (eye worm) oxidoreductase 0.0021 0.0013 0.0036
Trypanosoma brucei pyridine nucleotide-disulphide oxidoreductase, putative 0.02 0.0667 0.0659
Loa Loa (eye worm) hypothetical protein 0.0021 0.0013 0.0036
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.0021 0.0013 0.0026
Loa Loa (eye worm) norepinephrine transporter 0.0221 0.0746 0.2197
Mycobacterium tuberculosis Probable cytochrome P450 130 Cyp130 0.0042 0.0091 0.0225
Echinococcus granulosus carbonyl reductase 1 0.0021 0.0013 0.0011
Loa Loa (eye worm) hypothetical protein 0.0071 0.0196 0.0576
Loa Loa (eye worm) hypothetical protein 0.0058 0.0146 0.043
Entamoeba histolytica hypothetical protein 0.0037 0.0073 0.0916
Trichomonas vaginalis PIKK family atypical protein kinase 0.0026 0.0029 0.0094
Onchocerca volvulus 0.0021 0.0013 0.0027
Schistosoma mansoni phosphatidylserine receptor 0.0027 0.0036 0.0044
Brugia malayi bHLH-PAS transcription factor 0.012 0.0375 0.1095
Echinococcus granulosus uncharacterized sodium dependent transporter 0.0038 0.0073 0.0083
Onchocerca volvulus 0.0058 0.0146 0.0525
Trypanosoma brucei phosphatidylinositol 4-kinase, putative 0.0047 0.0109 0.0101
Schistosoma mansoni hypothetical protein 0.0109 0.0333 0.0401
Echinococcus granulosus Ankyrin 0.003 0.0047 0.0052
Loa Loa (eye worm) hypothetical protein 0.0063 0.0167 0.049
Brugia malayi RNA recognition motif domain containing protein 0.0066 0.0177 0.051
Loa Loa (eye worm) jmjC domain-containing protein 0.0027 0.0036 0.0105
Echinococcus granulosus voltage gated potassium channel 0.0022 0.0017 0.0016
Echinococcus multilocularis Nuclear hormone receptor family member nhr 41 0.0019 0.0006 0.0002
Plasmodium vivax thioredoxin reductase, putative 0.0945 0.3391 1
Mycobacterium ulcerans NADPH:adrenodoxin oxidoreductase FprB 0.02 0.0667 0.2443
Trypanosoma cruzi Lanosterol 14-alpha demethylase 0.0185 0.0613 0.0601
Echinococcus multilocularis PHD finger protein rhinoceros 0.0031 0.0051 0.0056
Loa Loa (eye worm) hypothetical protein 0.0063 0.0167 0.049
Schistosoma mansoni sodium-dependent neurotransmitter transporter 0.0038 0.0073 0.0088
Schistosoma mansoni cytochrome P450 0.0042 0.0091 0.0109
Plasmodium falciparum NAD(P)H-dependent glutamate synthase, putative 0.02 0.0667 0.1949
Trypanosoma brucei dihydrolipoamide dehydrogenase, point mutation 0.2018 0.7315 0.7313
Trichomonas vaginalis disulfide oxidoreductase, putative 0.02 0.0667 0.2467
Echinococcus multilocularis steroid dehydrogenase 0.0021 0.0013 0.0011
Leishmania major protein kinase, putative 0.0043 0.0094 0.0081
Echinococcus granulosus BC026374 protein S09 family 0.0063 0.0167 0.0196
Loa Loa (eye worm) O-glycosyl hydrolase family 30 protein 0.0272 0.0932 0.2746
Trypanosoma cruzi ERV/ALR sulfhydryl oxidase domain-containing protein 0.0036 0.0066 0.0054
Trichomonas vaginalis PIKK family atypical protein kinase 0.0035 0.0065 0.0226
Schistosoma mansoni survival motor neuron protein 0.0103 0.0312 0.0375
Schistosoma mansoni ap endonuclease 0.0042 0.0089 0.0107
Schistosoma mansoni nuclear receptor 2DBD-gamma 0.0019 0.0006 0.0007
Echinococcus multilocularis rhodopsin orphan GPCR 0.0058 0.0146 0.0171
Echinococcus multilocularis jumonji domain containing 1A 0.0027 0.0036 0.0039
Schistosoma mansoni steroid dehydrogenase 0.0021 0.0013 0.0015
Schistosoma mansoni hypothetical protein 0.0148 0.0478 0.0575
Echinococcus multilocularis biogenic amine (5HT) receptor 0.0058 0.0146 0.0171
Echinococcus multilocularis sodium and chloride dependent glycine 0.0038 0.0073 0.0083
Chlamydia trachomatis dihydrolipoyl dehydrogenase 0.0753 0.2689 1
Brugia malayi Retinol dehydrogenase 12 0.0021 0.0013 0.0026
Trypanosoma cruzi mitochondrial DNA polymerase beta, putative 0.0325 0.1123 0.1112
Mycobacterium tuberculosis Probable soluble pyridine nucleotide transhydrogenase SthA (STH) (NAD(P)(+) transhydrogenase [B-specific]) (nicotinamide nucleot 0.0753 0.2689 0.7715
Loa Loa (eye worm) hypothetical protein 0.0063 0.0167 0.049
Schistosoma mansoni coup transcription factor 0.0019 0.0006 0.0007
Echinococcus granulosus mitogen activated protein kinase 0.0109 0.0333 0.0396
Toxoplasma gondii NADH dehydrogenase (NDH2-II) 0.02 0.0667 0.1935
Trypanosoma brucei Phosphatidylinositol 3-kinase tor1 0.0047 0.0109 0.0101
Toxoplasma gondii histone lysine demethylase JMJC1/KDM5D/JARID1D 0.0027 0.0036 0.007
Echinococcus granulosus 7tm_1 domain containing protein 0.0058 0.0146 0.0171
Loa Loa (eye worm) nuclear hormone receptor family member nhr-31 0.0019 0.0006 0.0015
Schistosoma mansoni glutamate synthase 0.02 0.0667 0.0802
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.0021 0.0013 0.0026
Echinococcus granulosus sodium:chloride dependent neurotransmitter 0.0038 0.0073 0.0083
Echinococcus multilocularis 3 ketodihydrosphingosine reductase 0.0021 0.0013 0.0011
Schistosoma mansoni hypothetical protein 0.02 0.0667 0.0802
Echinococcus multilocularis Transcription factor, JmjC domain containing protein 0.0168 0.0549 0.0656
Onchocerca volvulus 0.0058 0.0146 0.0525
Toxoplasma gondii Erv1 / Alr family protein 0.0036 0.0066 0.0158
Brugia malayi hypoxia-induced factor 1 0.0502 0.1771 0.5218
Echinococcus multilocularis inositol monophosphatase 1 0.0077 0.0219 0.0258
Entamoeba histolytica NAD(FAD)-dependent dehydrogenase, putative 0.02 0.0667 1
Toxoplasma gondii Sodium:neurotransmitter symporter family protein 0.0038 0.0073 0.0179
Echinococcus granulosus pyridine nucleotide disulfide oxidoreductase 0.02 0.0667 0.0798
Onchocerca volvulus 0.0038 0.0073 0.0253
Brugia malayi dehydrogenases, short chain protein 9 0.0021 0.0013 0.0026
Mycobacterium tuberculosis Conserved hypothetical protein 0.0171 0.0561 0.1581
Leishmania major protein kinase, putative 0.0048 0.0112 0.0099
Schistosoma mansoni short chain dehydrogenase 0.0021 0.0013 0.0015
Trichomonas vaginalis phosphofructokinase, putative 0.012 0.0375 0.1382
Echinococcus granulosus Ataxin 2 N terminaldomain containing protein 0.0024 0.0024 0.0024
Loa Loa (eye worm) RNA recognition domain-containing protein domain-containing protein 0.0066 0.0177 0.0519
Schistosoma mansoni neuropeptide receptor 0.0058 0.0146 0.0176
Brugia malayi follicle stimulating hormone receptor 0.0058 0.0146 0.042
Trypanosoma cruzi Lanosterol 14-alpha demethylase 0.0185 0.0613 0.0601
Trypanosoma brucei trypanothione reductase 0.0945 0.3391 0.3386
Schistosoma mansoni polycystin 1-related 0.0148 0.0478 0.0575
Wolbachia endosymbiont of Brugia malayi thioredoxin reductase 0.02 0.0667 0.2443
Brugia malayi oxidoreductase 0.0021 0.0013 0.0026
Loa Loa (eye worm) glutathione reductase 0.0945 0.3391 1
Echinococcus granulosus orexin receptor type 2 0.0058 0.0146 0.0171
Echinococcus multilocularis conserved hypothetical protein 0.0021 0.0013 0.0011
Schistosoma mansoni chromobox protein 0.0077 0.0218 0.0262
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0019 0.0006 0.0005
Brugia malayi sulfakinin receptor protein 0.0058 0.0146 0.042
Giardia lamblia Glycerol-3-phosphate dehydrogenase 0.02 0.0667 0.2443
Trypanosoma brucei inositol-1(or 4)-monophosphatase 1, putative 0.0077 0.0219 0.0211
Leishmania major target of rapamycin (TOR) kinase 1, putative 0.0047 0.0109 0.0096
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.0021 0.0013 0.0026
Echinococcus granulosus epidermal retinal dehydrogenase 2 0.0021 0.0013 0.0011
Loa Loa (eye worm) hypothetical protein 0.0374 0.1302 0.3838
Mycobacterium tuberculosis Probable cytochrome P450 140 Cyp140 0.0042 0.0091 0.0225
Mycobacterium tuberculosis Probable NADPH:adrenodoxin oxidoreductase FprB (adrenodoxin reductase) (AR) (ferredoxin-NADP(+) reductase) 0.02 0.0667 0.1885
Brugia malayi cytochrome P450 0.0042 0.0091 0.0257
Echinococcus multilocularis potassium voltage gated channel subfamily H 0.0022 0.0017 0.0016
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.0021 0.0013 0.0026
Loa Loa (eye worm) hypothetical protein 0.0058 0.0146 0.043
Loa Loa (eye worm) hypothetical protein 0.0311 0.1073 0.3164
Echinococcus granulosus glutamate synthase 0.02 0.0667 0.0798
Schistosoma mansoni amine GPCR 0.0058 0.0146 0.0176
Echinococcus multilocularis lipoxygenase domain containing protein 0.0148 0.0478 0.0571
Giardia lamblia PHD finger protein 15 0.0031 0.0051 0.0141
Echinococcus multilocularis growth hormone secretagogue receptor type 1 0.0058 0.0146 0.0171
Onchocerca volvulus 0.0038 0.0073 0.0253
Echinococcus multilocularis neuropeptide Y receptor 0.0058 0.0146 0.0171
Mycobacterium tuberculosis Possible dehydrogenase/reductase 0.02 0.0667 0.1885
Schistosoma mansoni oxidoreductase short chain dehydrogenase/reductase family 0.0021 0.0013 0.0015
Loa Loa (eye worm) immunoglobulin I-set domain-containing protein 0.003 0.0046 0.0134
Schistosoma mansoni family S9 non-peptidase homologue (S09 family) 0.0374 0.1302 0.1567
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0058 0.0146 0.0176
Trichomonas vaginalis glucosylceramidase, putative 0.0272 0.0932 0.3454
Loa Loa (eye worm) G-protein-linked acetylcholine receptor protein 2 0.0058 0.0146 0.043
Treponema pallidum NADH oxidase 0.0753 0.2689 1
Echinococcus granulosus Basic leucine zipper bZIP transcription 0.0037 0.0073 0.0083
Schistosoma mansoni histone-lysine n-methyltransferase suv9 0.0108 0.0329 0.0396

Activities

Activity type Activity value Assay description Source Reference
Activity (binding) 0 Inhibition of porcine pancreatic trypsin upto 30 uM ChEMBL. 17253864
Activity (binding) 0 Inhibition of bovine plasma thrombin upto 30 uM ChEMBL. 17253864
Activity (binding) 0 Inhibition of human plasma plasmin upto 30 uM ChEMBL. 17253864
IC50 (binding) = 0.03 uM Inhibition of porcine pancreatic elastase ChEMBL. 17253864
IC50 (binding) = 0.3 uM Inhibition of bovine pancreatic alpha chymotrypsin ChEMBL. 17253864
Selectivity ratio (binding) > 100 Selectivity for bovine alpha chymotrypsin over porcine trypsin ChEMBL. 17253864
Selectivity ratio (binding) > 100 Selectivity for bovine alpha chymotrypsin over human plasmin ChEMBL. 17253864
Selectivity ratio (binding) > 100 Selectivity for bovine alpha chymotrypsin over bovine thrombin ChEMBL. 17253864
Selectivity ratio (binding) > 1000 Selectivity for porcine elastase over porcine trypsin ChEMBL. 17253864
Selectivity ratio (binding) > 1000 Selectivity for porcine elastase over human plasmin ChEMBL. 17253864
Selectivity ratio (binding) > 1000 Selectivity for porcine elastase over bovine thrombin ChEMBL. 17253864

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
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External resources for this compound

Bibliographic References

1 literature reference was collected for this gene.

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