Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Echinococcus multilocularis | nicotinic acetylcholine receptor alpha subunit | 0.0052 | 0.2049 | 0.2049 |
Echinococcus granulosus | nicotinic acetylcholine receptor subunit type | 0.0052 | 0.2049 | 0.2049 |
Brugia malayi | gamma-aminobutyric-acid receptor beta subunit precursor | 0.0052 | 0.2049 | 0.2049 |
Loa Loa (eye worm) | hypothetical protein | 0.0052 | 0.2049 | 0.2049 |
Loa Loa (eye worm) | hypothetical protein | 0.0052 | 0.2049 | 0.2049 |
Onchocerca volvulus | 0.0052 | 0.2049 | 1 | |
Loa Loa (eye worm) | ACC-1 protein | 0.0052 | 0.2049 | 0.2049 |
Echinococcus multilocularis | nicotinic acetylcholine receptor subunit alpha 8 | 0.0052 | 0.2049 | 0.2049 |
Loa Loa (eye worm) | hypothetical protein | 0.0052 | 0.2049 | 0.2049 |
Echinococcus multilocularis | acetylcholine receptor subunit beta 1 | 0.0052 | 0.2049 | 0.2049 |
Schistosoma mansoni | Cys-loop ligand gated ion channel subunit | 0.0052 | 0.2049 | 0.2049 |
Echinococcus granulosus | neuronal acetylcholine receptor subunit alpha 4 | 0.0052 | 0.2049 | 0.2049 |
Echinococcus multilocularis | acetylcholinesterase | 0.0145 | 1 | 1 |
Brugia malayi | Hypothetical glycine receptor like protein T20B12.9 in chromosome III | 0.0052 | 0.2049 | 0.2049 |
Loa Loa (eye worm) | acetylcholine receptor alpha subunit | 0.0052 | 0.2049 | 0.2049 |
Schistosoma mansoni | nAChR subunit | 0.0052 | 0.2049 | 0.2049 |
Loa Loa (eye worm) | nicotinic acetylcholine receptor alpha subunit | 0.0052 | 0.2049 | 0.2049 |
Echinococcus granulosus | nicotinic acetylcholine receptor alpha subunit | 0.0052 | 0.2049 | 0.2049 |
Onchocerca volvulus | Putative nachr subunit | 0.0052 | 0.2049 | 1 |
Entamoeba histolytica | hypothetical protein | 0.0028 | 0 | 0.5 |
Echinococcus granulosus | glycine receptor subunit alpha 1 | 0.0052 | 0.2049 | 0.2049 |
Brugia malayi | Neurotransmitter-gated ion-channel transmembrane region family protein | 0.0052 | 0.2049 | 0.2049 |
Echinococcus multilocularis | glycine receptor subunit alpha 1 | 0.0052 | 0.2049 | 0.2049 |
Loa Loa (eye worm) | hypothetical protein | 0.0052 | 0.2049 | 0.2049 |
Loa Loa (eye worm) | hypothetical protein | 0.0052 | 0.2049 | 0.2049 |
Loa Loa (eye worm) | acetylcholinesterase 1 | 0.0145 | 1 | 1 |
Brugia malayi | Neurotransmitter-gated ion-channel transmembrane region family protein | 0.0052 | 0.2049 | 0.2049 |
Brugia malayi | Neurotransmitter-gated ion-channel ligand binding domain containing protein | 0.0052 | 0.2049 | 0.2049 |
Brugia malayi | Neurotransmitter-gated ion-channel ligand binding domain containing protein | 0.0052 | 0.2049 | 0.2049 |
Echinococcus multilocularis | nicotinic acetylcholine receptor a11 subunit | 0.0052 | 0.2049 | 0.2049 |
Loa Loa (eye worm) | ACC-1 protein | 0.0052 | 0.2049 | 0.2049 |
Schistosoma mansoni | Cys-loop ligand gated ion channel subunit | 0.0052 | 0.2049 | 0.2049 |
Echinococcus granulosus | glycine receptor subunit alpha 1 | 0.0052 | 0.2049 | 0.2049 |
Schistosoma mansoni | nAChR subunit | 0.0052 | 0.2049 | 0.2049 |
Echinococcus multilocularis | glycine receptor subunit alpha 1 | 0.0052 | 0.2049 | 0.2049 |
Brugia malayi | acetylcholine receptor protein, alpha-like chain, putative | 0.0052 | 0.2049 | 0.2049 |
Schistosoma mansoni | nAChR subunit | 0.0052 | 0.2049 | 0.2049 |
Echinococcus granulosus | nicotinic acetylcholine receptor beta 1 subunit | 0.0052 | 0.2049 | 0.2049 |
Schistosoma mansoni | Cys-loop ligand gated ion channel subunit | 0.0052 | 0.2049 | 0.2049 |
Brugia malayi | Neurotransmitter-gated ion-channel ligand binding domain containing protein | 0.0052 | 0.2049 | 0.2049 |
Schistosoma mansoni | nAChR subunit | 0.0052 | 0.2049 | 0.2049 |
Echinococcus multilocularis | nAChR subunit | 0.0052 | 0.2049 | 0.2049 |
Echinococcus granulosus | nicotinic acetylcholine receptor subunit alpha 8 | 0.0052 | 0.2049 | 0.2049 |
Echinococcus multilocularis | carboxylesterase 5A | 0.0145 | 1 | 1 |
Echinococcus granulosus | carboxylesterase 5A | 0.0145 | 1 | 1 |
Onchocerca volvulus | 0.0052 | 0.2049 | 1 | |
Loa Loa (eye worm) | hypothetical protein | 0.0052 | 0.2049 | 0.2049 |
Loa Loa (eye worm) | glutamate-gated chloride channel alpha3A subunit | 0.0052 | 0.2049 | 0.2049 |
Onchocerca volvulus | 0.0052 | 0.2049 | 1 | |
Echinococcus granulosus | glycine receptor subunit alpha 1 | 0.0052 | 0.2049 | 0.2049 |
Loa Loa (eye worm) | hypothetical protein | 0.0052 | 0.2049 | 0.2049 |
Schistosoma mansoni | nAChR subunit | 0.0052 | 0.2049 | 0.2049 |
Brugia malayi | acetylcholine receptor, alpha-type subunit unc-38 precursor | 0.0052 | 0.2049 | 0.2049 |
Brugia malayi | Neurotransmitter-gated ion-channel transmembrane region family protein | 0.0052 | 0.2049 | 0.2049 |
Echinococcus granulosus | acetylcholinesterase | 0.0145 | 1 | 1 |
Loa Loa (eye worm) | carboxylesterase | 0.0145 | 1 | 1 |
Schistosoma mansoni | nAChR subunit (ShAR1-beta2-like) | 0.0052 | 0.2049 | 0.2049 |
Echinococcus granulosus | nicotinic acetylcholine receptor a11 subunit | 0.0052 | 0.2049 | 0.2049 |
Brugia malayi | Cation transporter family protein | 0.0052 | 0.2049 | 0.2049 |
Loa Loa (eye worm) | LGC-31 protein | 0.0052 | 0.2049 | 0.2049 |
Onchocerca volvulus | 0.0052 | 0.2049 | 1 | |
Onchocerca volvulus | 0.0052 | 0.2049 | 1 | |
Brugia malayi | Neurotransmitter-gated ion-channel ligand binding domain containing protein | 0.0052 | 0.2049 | 0.2049 |
Loa Loa (eye worm) | excitatory GABA receptor EXP-1A | 0.0052 | 0.2049 | 0.2049 |
Loa Loa (eye worm) | hypothetical protein | 0.0052 | 0.2049 | 0.2049 |
Brugia malayi | Neurotransmitter-gated ion-channel ligand binding domain containing protein | 0.0052 | 0.2049 | 0.2049 |
Echinococcus multilocularis | glycine receptor subunit beta | 0.0052 | 0.2049 | 0.2049 |
Loa Loa (eye worm) | hypothetical protein | 0.0052 | 0.2049 | 0.2049 |
Schistosoma mansoni | family S9 non-peptidase homologue (S09 family) | 0.0145 | 1 | 1 |
Echinococcus multilocularis | glycine receptor subunit beta | 0.0052 | 0.2049 | 0.2049 |
Loa Loa (eye worm) | hypothetical protein | 0.0145 | 1 | 1 |
Onchocerca volvulus | 0.0052 | 0.2049 | 1 | |
Loa Loa (eye worm) | hypothetical protein | 0.0052 | 0.2049 | 0.2049 |
Loa Loa (eye worm) | hypothetical protein | 0.0052 | 0.2049 | 0.2049 |
Brugia malayi | Cation transporter family protein | 0.0052 | 0.2049 | 0.2049 |
Brugia malayi | nicotinic acetylcholine receptor alpha subunit, putative | 0.0052 | 0.2049 | 0.2049 |
Schistosoma mansoni | nAChR subunit | 0.0052 | 0.2049 | 0.2049 |
Brugia malayi | nicotinic acetylcholine receptor beta-1 chain precursor | 0.0052 | 0.2049 | 0.2049 |
Echinococcus multilocularis | nicotinic acetylcholine receptor beta 1 subunit | 0.0052 | 0.2049 | 0.2049 |
Schistosoma mansoni | nAChR subunit (ShAR1-beta-like) | 0.0052 | 0.2049 | 0.2049 |
Loa Loa (eye worm) | hypothetical protein | 0.0052 | 0.2049 | 0.2049 |
Schistosoma mansoni | nAChR subunit (ShAR1-alpha-like) | 0.0052 | 0.2049 | 0.2049 |
Loa Loa (eye worm) | hypothetical protein | 0.0052 | 0.2049 | 0.2049 |
Echinococcus granulosus | acetylcholine receptor subunit beta 1 | 0.0052 | 0.2049 | 0.2049 |
Schistosoma mansoni | nAChR subunit | 0.0052 | 0.2049 | 0.2049 |
Loa Loa (eye worm) | hypothetical protein | 0.0052 | 0.2049 | 0.2049 |
Brugia malayi | acetylcholine receptor alpha subunit precursor, putative | 0.0052 | 0.2049 | 0.2049 |
Echinococcus granulosus | Cys loop ligand gated ion channel subunit | 0.0052 | 0.2049 | 0.2049 |
Loa Loa (eye worm) | hypothetical protein | 0.0052 | 0.2049 | 0.2049 |
Loa Loa (eye worm) | hypothetical protein | 0.0052 | 0.2049 | 0.2049 |
Loa Loa (eye worm) | hypothetical protein | 0.0145 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0052 | 0.2049 | 0.2049 |
Echinococcus granulosus | glycine receptor subunit beta | 0.0052 | 0.2049 | 0.2049 |
Brugia malayi | Neurotransmitter-gated ion-channel ligand binding domain containing protein | 0.0052 | 0.2049 | 0.2049 |
Echinococcus granulosus | acetylcholinesterase | 0.0145 | 1 | 1 |
Echinococcus multilocularis | neuronal acetylcholine receptor subunit alpha 4 | 0.0052 | 0.2049 | 0.2049 |
Loa Loa (eye worm) | nicotinic acetylcholine receptor non-alpha subunit | 0.0052 | 0.2049 | 0.2049 |
Loa Loa (eye worm) | ligand-Gated ion Channel family member | 0.0052 | 0.2049 | 0.2049 |
Echinococcus multilocularis | Cys loop ligand gated ion channel subunit | 0.0052 | 0.2049 | 0.2049 |
Echinococcus multilocularis | glycine receptor subunit alpha 1 | 0.0052 | 0.2049 | 0.2049 |
Echinococcus granulosus | glycine receptor subunit beta | 0.0052 | 0.2049 | 0.2049 |
Loa Loa (eye worm) | hypothetical protein | 0.0052 | 0.2049 | 0.2049 |
Echinococcus multilocularis | acetylcholinesterase | 0.0145 | 1 | 1 |
Brugia malayi | Cation transporter family protein | 0.0052 | 0.2049 | 0.2049 |
Echinococcus granulosus | nAChR subunit | 0.0052 | 0.2049 | 0.2049 |
Loa Loa (eye worm) | hypothetical protein | 0.0052 | 0.2049 | 0.2049 |
Brugia malayi | Carboxylesterase family protein | 0.0145 | 1 | 1 |
Brugia malayi | excitatory GABA receptor EXP-1A | 0.0052 | 0.2049 | 0.2049 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.
1 literature reference was collected for this gene.