Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Giardia lamblia | Fructose-bisphosphate aldolase | 0.0296 | 0.1189 | 1 |
Brugia malayi | acetyltransferase, GNAT family protein | 0.0147 | 0.0581 | 0.0577 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0007 | 0.001 | 0.0085 |
Trichomonas vaginalis | fructose-bisphosphate aldolase, putative | 0.0296 | 0.1189 | 1 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0007 | 0.001 | 0.0085 |
Trichomonas vaginalis | chromodomain-helicase-DNA-binding protein, putative | 0.0007 | 0.001 | 0.0085 |
Trichomonas vaginalis | fructose-bisphosphate aldolase, putative | 0.0296 | 0.1189 | 1 |
Entamoeba histolytica | fructose-1,6-bisphosphate aldolase, putative | 0.0296 | 0.1189 | 1 |
Trichomonas vaginalis | chromodomain helicase DNA binding protein, putative | 0.0007 | 0.001 | 0.0085 |
Toxoplasma gondii | histone lysine methyltransferase SET1 | 0.0059 | 0.0222 | 0.0064 |
Echinococcus granulosus | histone acetyltransferase KAT2B | 0.0043 | 0.0159 | 0.0155 |
Treponema pallidum | fructose-bisphosphate aldolase | 0.0296 | 0.1189 | 0.5 |
Schistosoma mansoni | cpg binding protein | 0.0029 | 0.0102 | 0.0102 |
Loa Loa (eye worm) | fructose-1,6-bisphosphatase | 0.2454 | 1 | 1 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0007 | 0.001 | 0.0085 |
Mycobacterium tuberculosis | Probable fructose-bisphosphate aldolase Fba | 0.0144 | 0.0572 | 0.5 |
Trichomonas vaginalis | chromodomain-helicase-DNA-binding protein, putative | 0.0007 | 0.001 | 0.0085 |
Schistosoma mansoni | mixed-lineage leukemia protein mll | 0.0007 | 0.0013 | 0.0012 |
Toxoplasma gondii | sedoheptulose-1,7-bisphosphatase | 0.0913 | 0.3708 | 0.3606 |
Loa Loa (eye worm) | CXXC zinc finger family protein | 0.0029 | 0.0102 | 0.0097 |
Trichomonas vaginalis | chromodomain helicase DNA binding protein, putative | 0.0007 | 0.001 | 0.0085 |
Schistosoma mansoni | zinc finger protein | 0.0005 | 0.0005 | 0.0004 |
Trichomonas vaginalis | fructose-bisphosphate aldolase, putative | 0.0296 | 0.1189 | 1 |
Plasmodium vivax | histone acetyltransferase GCN5, putative | 0.0043 | 0.0159 | 1 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0007 | 0.001 | 0.0085 |
Trichomonas vaginalis | chromodomain helicase DNA binding protein, putative | 0.0007 | 0.001 | 0.0085 |
Echinococcus granulosus | fructose 16 bisphosphatase 1 | 0.2454 | 1 | 1 |
Trypanosoma brucei | fructose-1,6-bisphosphatase | 0.2454 | 1 | 1 |
Leishmania major | 0.2454 | 1 | 0.5 | |
Schistosoma mansoni | fructose-16-bisphosphatase-related | 0.2454 | 1 | 1 |
Trypanosoma cruzi | fructose-1,6-bisphosphatase, cytosolic, putative | 0.2454 | 1 | 1 |
Echinococcus granulosus | dnaJ subfamily B | 0.0414 | 0.1671 | 0.1667 |
Echinococcus granulosus | histone acetyltransferase KAT2B | 0.0142 | 0.0565 | 0.056 |
Mycobacterium leprae | Probable fructose bisphosphate aldolase Fba | 0.0144 | 0.0572 | 0.5 |
Loa Loa (eye worm) | histone methyltransferase | 0.0009 | 0.002 | 0.0015 |
Schistosoma mansoni | cpg binding protein | 0.0031 | 0.0109 | 0.0108 |
Trichomonas vaginalis | helicase, putative | 0.0007 | 0.001 | 0.0085 |
Brugia malayi | CXXC zinc finger family protein | 0.0029 | 0.0102 | 0.0097 |
Entamoeba histolytica | fructose-1,6-bisphosphate aldolase, putative | 0.0296 | 0.1189 | 1 |
Echinococcus granulosus | histone lysine N methyltransferase MLL3 | 0.0007 | 0.0013 | 0.0008 |
Trichomonas vaginalis | fructose-bisphosphate aldolase, putative | 0.0296 | 0.1189 | 1 |
Onchocerca volvulus | 0.0029 | 0.0102 | 0.5 | |
Trichomonas vaginalis | conserved hypothetical protein | 0.0007 | 0.001 | 0.0085 |
Brugia malayi | F/Y-rich N-terminus family protein | 0.0009 | 0.0019 | 0.0015 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0007 | 0.001 | 0.0085 |
Trichomonas vaginalis | fructose-bisphosphate aldolase, putative | 0.0296 | 0.1189 | 1 |
Schistosoma mansoni | bromodomain containing protein | 0.0005 | 0.0005 | 0.0004 |
Schistosoma mansoni | mixed-lineage leukemia protein mll | 0.0062 | 0.0235 | 0.0234 |
Schistosoma mansoni | gcn5proteinral control of amino-acid synthesis 5-like 2 gcnl2 | 0.0147 | 0.0581 | 0.0581 |
Trichomonas vaginalis | chromodomain helicase DNA binding protein, putative | 0.0007 | 0.001 | 0.0085 |
Trichomonas vaginalis | chromodomain helicase DNA binding protein, putative | 0.0007 | 0.001 | 0.0085 |
Loa Loa (eye worm) | acetyltransferase | 0.0147 | 0.0581 | 0.0577 |
Trichomonas vaginalis | bromodomain-containing protein, putative | 0.0043 | 0.0159 | 0.1338 |
Trichomonas vaginalis | fructose-bisphosphate aldolase, putative | 0.0296 | 0.1189 | 1 |
Trichomonas vaginalis | chromodomain helicase DNA binding protein, putative | 0.0007 | 0.001 | 0.0085 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0007 | 0.001 | 0.0085 |
Echinococcus multilocularis | dnaJ subfamily B | 0.0414 | 0.1671 | 0.1667 |
Trichomonas vaginalis | fructose-bisphosphate aldolase, putative | 0.0296 | 0.1189 | 1 |
Schistosoma mansoni | hypothetical protein | 0.0414 | 0.1671 | 0.1671 |
Trichomonas vaginalis | fructose-bisphosphate aldolase, putative | 0.0296 | 0.1189 | 1 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0007 | 0.001 | 0.0085 |
Schistosoma mansoni | bromodomain containing protein | 0.0005 | 0.0005 | 0.0004 |
Echinococcus multilocularis | histone lysine N methyltransferase MLL3 | 0.0007 | 0.0013 | 0.0008 |
Echinococcus multilocularis | cpg binding protein | 0.0031 | 0.0109 | 0.0104 |
Mycobacterium ulcerans | fructose-bisphosphate aldolase | 0.0144 | 0.0572 | 0.5 |
Echinococcus granulosus | cpg binding protein | 0.0031 | 0.0109 | 0.0104 |
Echinococcus multilocularis | gcn5proteinral control of amino acid synthesis | 0.0147 | 0.0581 | 0.0577 |
Echinococcus multilocularis | fructose 1,6 bisphosphatase 1 | 0.2454 | 1 | 1 |
Toxoplasma gondii | fructose-bisphospatase I | 0.0913 | 0.3708 | 0.3606 |
Plasmodium falciparum | histone acetyltransferase GCN5 | 0.004 | 0.0144 | 0.5 |
Echinococcus multilocularis | histone lysine N methyltransferase MLL3 | 0.0009 | 0.002 | 0.0015 |
Echinococcus granulosus | mixed lineage leukemia protein mll | 0.0007 | 0.0013 | 0.0008 |
Trypanosoma cruzi | fructose-1,6-bisphosphatase, cytosolic, putative | 0.2454 | 1 | 1 |
Echinococcus granulosus | histone lysine N methyltransferase MLL3 | 0.0009 | 0.002 | 0.0015 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0007 | 0.001 | 0.0085 |
Schistosoma mansoni | cpg binding protein | 0.0031 | 0.0109 | 0.0108 |
Toxoplasma gondii | fructose-bisphospatase II | 0.2454 | 1 | 1 |
Echinococcus multilocularis | mixed lineage leukemia protein mll | 0.0007 | 0.0013 | 0.0008 |
Trichomonas vaginalis | cat eye syndrome critical region protein 2, cscr2, putative | 0.0043 | 0.0159 | 0.1338 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.
1 literature reference was collected for this gene.