Detailed information for compound 41257

Basic information

Technical information
  • Name: Unnamed compound
  • MW: 524.702 | Formula: C30H47F3N2O2
  • H donors: 0 H acceptors: 2 LogP: 10.45 Rotable bonds: 20
    Rule of 5 violations (Lipinski): 2
  • SMILES: CCCCCCCCCCCCCCCCN(C(=O)C(F)(F)F)c1ccc(cc1)C(=O)N1CCCCC1
  • InChi: 1S/C30H47F3N2O2/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-18-25-35(29(37)30(31,32)33)27-21-19-26(20-22-27)28(36)34-23-16-15-17-24-34/h19-22H,2-18,23-25H2,1H3
  • InChiKey: UDHXQCGOATZESO-UHFFFAOYSA-N  


Substructure search Similarity search

Network

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Synonyms

No synonyms found for this compound

Targets

Known targets for this compound

No curated genes were found associated with this compound

Predicted pathogen targets for this compound

By orthology
No druggable targets predicted by orthology data
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Loa Loa (eye worm) hypothetical protein 0.0033 0.0089 0.0677
Onchocerca volvulus 0.0033 0.0089 0.209
Loa Loa (eye worm) hypothetical protein 0.0026 0.0065 0.0474
Loa Loa (eye worm) hypothetical protein 0.0033 0.0089 0.0677
Echinococcus multilocularis fmrfamide receptor 0.0033 0.0089 0.046
Plasmodium falciparum cysteine--tRNA ligase 0.0043 0.0122 0.319
Mycobacterium tuberculosis Probable cytochrome P450 143 Cyp143 0.0022 0.0051 0.004
Echinococcus multilocularis dihydrolipoamide dehydrogenase 0.0023 0.0056 0.0283
Echinococcus granulosus serotonin receptor 0.0033 0.0089 0.0482
Echinococcus granulosus peptide allatostatin:somatostatin 0.0033 0.0089 0.0482
Schistosoma mansoni thyrotropin-releasing hormone receptor 0.0033 0.0089 0.0482
Entamoeba histolytica cysteinyl-tRNA synthetase, putative 0.0043 0.0122 0.307
Schistosoma mansoni lamin 0.0056 0.0168 0.0914
Brugia malayi putative neuropeptide receptor 0.0033 0.0089 0.0949
Trichomonas vaginalis Importin beta-1 subunit, putative 0.0026 0.0066 0.1836
Leishmania major mitogen activated protein kinase, putative,map kinase, putative 0.0057 0.0173 0.4632
Giardia lamblia Ubiquitin carboxyl-terminal hydrolase 4 0.0073 0.0228 1
Echinococcus multilocularis rhodopsin orphan GPCR 0.0033 0.0089 0.046
Echinococcus granulosus G protein coupled receptor 139 0.0033 0.0089 0.0482
Trypanosoma brucei transcription factor BTF3, putative 0.0112 0.036 1
Brugia malayi Kazal-type serine protease inhibitor domain containing protein 0.0081 0.0255 0.2728
Schistosoma mansoni organic anion transporter 0.0119 0.0384 0.2089
Loa Loa (eye worm) cysteinyl tRNA synthetase 1 0.0043 0.0122 0.0968
Loa Loa (eye worm) hypothetical protein 0.0033 0.0089 0.0677
Echinococcus multilocularis neuropeptide Y receptor 0.0033 0.0089 0.046
Mycobacterium ulcerans cysteinyl-tRNA synthetase 0.2926 1 1
Trypanosoma brucei dihydrolipoamide dehydrogenase, point mutation 0.0023 0.0056 0.1517
Schistosoma mansoni agrin 0.0081 0.0255 0.1385
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0011 0.0013 0.0048
Echinococcus granulosus potassium voltage gated channel subfamily H 0.0077 0.0238 0.1295
Brugia malayi SPARC precursor 0.0081 0.0255 0.2728
Echinococcus multilocularis rhodopsin orphan GPCR 0.0033 0.0089 0.046
Loa Loa (eye worm) 5-hydroxytryptamine 2C receptor 0.0033 0.0089 0.0677
Toxoplasma gondii ATP-binding cassette transporter ABC.B1 0.0012 0.0017 0.0162
Loa Loa (eye worm) hypothetical protein 0.0075 0.0233 0.1927
Brugia malayi Hypothetical 52.5 kDa protein ZK945.1 in chromosome II, putative 0.0075 0.0233 0.2494
Schistosoma mansoni camp-dependent protein kinase type II regulatory subunit 0.001 0.0011 0.0057
Echinococcus multilocularis potassium voltage gated channel subfamily H 0.0077 0.0238 0.1274
Mycobacterium tuberculosis Conserved protein 0.0075 0.0233 0.0222
Echinococcus granulosus rhodopsin orphan GPCR 0.0033 0.0089 0.0482
Leishmania major acetoin dehydrogenase e3 component-like protein 0.0023 0.0056 0.1304
Echinococcus multilocularis ATP binding cassette subfamily B (MDR:TAP) 0.0012 0.0017 0.0067
Giardia lamblia Cysteinyl-tRNA synthetase 0.0043 0.0122 0.5141
Onchocerca volvulus Steroid hormone receptor family member cnr14 homolog 0.0011 0.0013 0.0067
Toxoplasma gondii Kazal-type serine protease inhibitor domain-containing protein 0.0081 0.0255 0.6534
Brugia malayi G-protein coupled receptor 0.0033 0.0089 0.0949
Trichomonas vaginalis voltage and ligand gated potassium channel, putative 0.0015 0.0028 0.0771
Leishmania major GTP-binding protein, putative 0.0024 0.0058 0.1352
Plasmodium vivax basic transcription factor 3b, putative 0.0112 0.036 1
Brugia malayi hypothetical protein 0.0033 0.0089 0.0949
Loa Loa (eye worm) hypothetical protein 0.0081 0.0255 0.2117
Schistosoma mansoni voltage-gated potassium channel 0.0084 0.0262 0.1426
Brugia malayi beta-NAC-like protein 0.0112 0.036 0.386
Loa Loa (eye worm) hypothetical protein 0.0011 0.0013 0.0022
Echinococcus granulosus rhodopsin orphan GPCR 0.0033 0.0089 0.0482
Schistosoma mansoni multidrug resistance protein 0.0012 0.0017 0.009
Chlamydia trachomatis cysteine--tRNA ligase 0.0043 0.0122 1
Echinococcus multilocularis g protein linked acetylcholine receptor gar 2a 0.0033 0.0089 0.046
Mycobacterium ulcerans hypothetical protein 0.0075 0.0233 0.0222
Trypanosoma cruzi mitogen activated protein kinase 4, putative 0.0057 0.0173 0.4336
Schistosoma mansoni importin beta-1 0.0032 0.0087 0.0474
Loa Loa (eye worm) hypothetical protein 0.0033 0.0089 0.0677
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0033 0.0089 0.046
Mycobacterium tuberculosis Probable cytochrome P450 125 Cyp125 0.0022 0.0051 0.004
Echinococcus granulosus hyperpolarization activated cyclic 0.0015 0.0028 0.0151
Echinococcus granulosus tm gpcr rhodopsin 0.0033 0.0089 0.0482
Loa Loa (eye worm) hypothetical protein 0.0015 0.0026 0.0134
Loa Loa (eye worm) hypothetical protein 0.0033 0.0089 0.0677
Schistosoma mansoni opsin-like receptor 0.0033 0.0089 0.0482
Schistosoma mansoni neuropeptide receptor 0.0033 0.0089 0.0482
Loa Loa (eye worm) hypothetical protein 0.0119 0.0384 0.324
Echinococcus multilocularis cAMP dependent protein kinase regulatory 0.001 0.0011 0.0034
Echinococcus multilocularis g-protein coupled receptor 0.0033 0.0089 0.046
Schistosoma mansoni neuropeptide receptor 0.0033 0.0089 0.0482
Echinococcus granulosus cGMP dependent protein kinase 0.0011 0.0012 0.0067
Trichomonas vaginalis D-aminoacylase, putative 0.0075 0.0233 0.6462
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0023 0.0056 0.1221
Giardia lamblia GTP-binding nuclear protein RAN/TC4 0.0024 0.0058 0.2178
Brugia malayi Importin beta-1 subunit 0.0032 0.0087 0.0934
Onchocerca volvulus 0.0033 0.0089 0.209
Brugia malayi Hypothetical UPF0028 protein ZK370.4 in chromosome III, putative 0.001 0.0011 0.0113
Echinococcus granulosus thioredoxin glutathione reductase 0.0068 0.0207 0.1128
Echinococcus multilocularis lamin 0.0056 0.0168 0.0893
Echinococcus granulosus neuropeptide Y receptor 0.0033 0.0089 0.0482
Loa Loa (eye worm) cytochrome P450 0.0022 0.0051 0.0349
Loa Loa (eye worm) cyclic-nucleotide gated cation channel 0.0015 0.0028 0.015
Trypanosoma brucei cytochrome P450, putative 0.0076 0.0236 0.6532
Leishmania major importin beta-1 subunit, putative 0.0026 0.0066 0.159
Schistosoma mansoni FTZ-F1 nuclear receptor-like protein 0.0011 0.0013 0.0071
Echinococcus granulosus neuropeptide FF receptor 2 0.0033 0.0089 0.0482
Trypanosoma brucei cysteinyl-tRNA synthetase, putative 0.0043 0.0122 0.3357
Schistosoma mansoni biogenic amine receptor 0.0033 0.0089 0.0482
Brugia malayi hypothetical protein 0.0119 0.0384 0.4115
Schistosoma mansoni serine/threonine protein kinase 0.0011 0.0012 0.0067
Schistosoma mansoni hypothetical protein 0.001 0.0011 0.0057
Echinococcus granulosus hyperpolarization activated cyclic 0.0015 0.0028 0.0151
Trichomonas vaginalis ATP-binding cassette transporter, putative 0.0012 0.0017 0.0461
Trichomonas vaginalis lipid A export ATP-binding/permease protein msba, putative 0.0012 0.0017 0.0461
Onchocerca volvulus Netrin receptor homolog 0.0014 0.0026 0.0403
Trichomonas vaginalis CMGC family protein kinase 0.0057 0.0173 0.4789
Mycobacterium leprae Conserved hypothetical protein 0.001 0.0011 0.0011
Schistosoma mansoni biogenic amine receptor 0.0033 0.0089 0.0482
Mycobacterium tuberculosis Possible conserved lipoprotein LpqK 0.0075 0.0233 0.0222
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0011 0.0013 0.0071
Onchocerca volvulus 0.0033 0.0089 0.209
Mycobacterium tuberculosis Probable lipase LipE 0.0075 0.0233 0.0222
Loa Loa (eye worm) hypothetical protein 0.0012 0.0016 0.0049
Loa Loa (eye worm) hypothetical protein 0.0033 0.0089 0.0677
Echinococcus multilocularis geminin 0.0544 0.1839 1
Loa Loa (eye worm) hypothetical protein 0.0056 0.0168 0.1367
Trypanosoma brucei cyclic nucleotide-binding domain containing protein, putative 0.001 0.0011 0.0244
Brugia malayi Nuclear hormone receptor family member nhr-14 0.0011 0.0013 0.014
Loa Loa (eye worm) hypothetical protein 0.0033 0.0089 0.0677
Echinococcus multilocularis alpha 1A adrenergic receptor 0.0033 0.0089 0.046
Trypanosoma cruzi MFS transporter, putative 0.0119 0.0384 1
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0033 0.0089 0.0482
Brugia malayi Nuclear hormone receptor family member nhr-40 0.0011 0.0013 0.014
Brugia malayi Melatonin receptor type 1A 0.0033 0.0089 0.0949
Trypanosoma cruzi GTP-binding nuclear protein rtb2, putative 0.0024 0.0058 0.1265
Mycobacterium tuberculosis Probable cytochrome P450 140 Cyp140 0.0022 0.0051 0.004
Schistosoma mansoni histamine h1 receptor 0.0033 0.0089 0.0482
Toxoplasma gondii ABC1 family protein 0.0075 0.0233 0.5949
Loa Loa (eye worm) hypothetical protein 0.0081 0.0255 0.2117
Trypanosoma cruzi trypanothione reductase, putative 0.0023 0.0056 0.1221
Schistosoma mansoni cysteinyl-tRNA synthetase 0.0043 0.0122 0.0664
Brugia malayi sulfakinin receptor protein 0.0033 0.0089 0.0949
Schistosoma mansoni hypothetical protein 0.0055 0.0166 0.0902
Toxoplasma gondii Kazal-type serine protease inhibitor domain-containing protein 0.0081 0.0255 0.6534
Brugia malayi Intermediate filament tail domain containing protein 0.0056 0.0168 0.1801
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0011 0.0013 0.014
Loa Loa (eye worm) glutathione reductase 0.0068 0.0207 0.1708
Echinococcus multilocularis G protein coupled receptor 139 0.0033 0.0089 0.046
Schistosoma mansoni retinoblastoma-binding protein 4 (rbbp4) 0.0015 0.0026 0.0141
Echinococcus multilocularis ubiquitin specific protease 41 0.0073 0.0228 0.1217
Trypanosoma brucei ubiquitin carboxyl-terminal hydrolase, putative 0.0073 0.0228 0.6299
Trichomonas vaginalis glutathione reductase, putative 0.0023 0.0056 0.1559
Leishmania major mitogen activated protein kinase 4, putative;with=GeneDB:LmxM19.1440 0.0057 0.0173 0.4632
Onchocerca volvulus 0.0119 0.0384 1
Mycobacterium ulcerans cytochrome P450 144A4 Cyp144A4 0.0022 0.0051 0.004
Brugia malayi G protein-coupled receptor F59B2.13 0.0033 0.0089 0.0949
Plasmodium vivax cysteine--tRNA ligase, putative 0.0043 0.0122 0.319
Onchocerca volvulus 0.0033 0.0089 0.209
Echinococcus multilocularis rhodopsin orphan GPCR 0.0033 0.0089 0.046
Mycobacterium tuberculosis Probable cytochrome P450 137 Cyp137 0.0022 0.0051 0.004
Echinococcus multilocularis multidrug resistance protein 1 0.0012 0.0017 0.0067
Loa Loa (eye worm) GTP-binding nuclear protein RAN/TC4 0.0024 0.0058 0.041
Loa Loa (eye worm) hypothetical protein 0.0119 0.0384 0.324
Schistosoma mansoni similar to Protein C20orf152 homolog 0.001 0.0011 0.0057
Leishmania major ATP-binding cassette protein subfamily B, member 2, putative 0.0012 0.0017 0.0174
Echinococcus granulosus patatin phospholipase domain containing protein 0.001 0.0011 0.0057
Echinococcus granulosus cytoplasmic intermediate filament protein 0.0027 0.0069 0.0374
Schistosoma mansoni hypothetical protein 0.0022 0.0051 0.0276
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0011 0.0013 0.014
Loa Loa (eye worm) intermediate filament tail domain-containing protein 0.0056 0.0168 0.1367
Loa Loa (eye worm) hypothetical protein 0.0033 0.0089 0.0677
Brugia malayi prostaglandin transporter 0.0119 0.0384 0.4115
Trypanosoma cruzi hypothetical protein, conserved 0.0075 0.0233 0.5949
Leishmania major 2-oxoglutarate dehydrogenase, e3 component, lipoamidedehydrogenase-like protein 0.0023 0.0056 0.1304
Echinococcus multilocularis patatin phospholipase domain containing protein 0.001 0.0011 0.0034
Brugia malayi hypothetical protein 0.0033 0.0089 0.0949
Echinococcus granulosus cGMP dependent protein kinase 1 0.0011 0.0012 0.0067
Loa Loa (eye worm) hypothetical protein 0.0022 0.0052 0.0358
Echinococcus granulosus alpha 1A adrenergic receptor 0.0033 0.0089 0.0482
Brugia malayi gonadotropin-releasing hormone receptor 2 0.0033 0.0089 0.0949
Echinococcus multilocularis sex peptide receptor 0.0033 0.0089 0.046
Echinococcus multilocularis rhodopsin orphan GPCR 0.0033 0.0089 0.046
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0075 0.0233 0.1266
Loa Loa (eye worm) hypothetical protein 0.0033 0.0089 0.0677
Trichomonas vaginalis lipid A export ATP-binding/permease protein msba, putative 0.0012 0.0017 0.0461
Schistosoma mansoni voltage-gated potassium channel 0.0015 0.0028 0.0151
Loa Loa (eye worm) hypothetical protein 0.0033 0.0089 0.0677
Plasmodium falciparum cGMP-dependent protein kinase 0.0011 0.0012 0.0051
Brugia malayi Cytochrome P450 family protein 0.0076 0.0236 0.2528
Onchocerca volvulus 0.0033 0.0089 0.209
Onchocerca volvulus 0.0033 0.0089 0.209
Schistosoma mansoni serine/threonine protein kinase 0.0011 0.0012 0.0067
Schistosoma mansoni biogenic amine (octopamine/dopamine) receptor 0.0033 0.0089 0.0482
Mycobacterium tuberculosis Conserved protein 0.0075 0.0233 0.0222
Mycobacterium ulcerans cytochrome p450 150 cyp150 0.0022 0.0051 0.004
Onchocerca volvulus 0.0033 0.0089 0.209
Mycobacterium ulcerans cytochrome P450 150A6 Cyp150A6 0.0022 0.0051 0.004
Plasmodium falciparum thioredoxin reductase 0.0068 0.0207 0.5631
Trypanosoma cruzi ubiquitin carboxyl-terminal hydrolase, putative 0.0073 0.0228 0.581
Brugia malayi beta-lactamase family protein 0.0075 0.0233 0.2494
Mycobacterium tuberculosis Conserved protein 0.0075 0.0233 0.0222
Onchocerca volvulus 0.0033 0.0089 0.209
Loa Loa (eye worm) hypothetical protein 0.0075 0.0233 0.1927
Loa Loa (eye worm) G-protein-linked acetylcholine receptor protein 2 0.0033 0.0089 0.0677
Leishmania major protein kinase, putative 0.0011 0.0012 0.0051
Onchocerca volvulus 0.0075 0.0233 0.5949
Echinococcus multilocularis ecdysone induced protein 78C 0.0011 0.0013 0.0048
Mycobacterium tuberculosis Probable cytochrome P450 132 Cyp132 0.0022 0.0051 0.004
Echinococcus granulosus lamin 0.0056 0.0168 0.0914
Trypanosoma brucei dihydrolipoamide dehydrogenase 0.0023 0.0056 0.1517
Schistosoma mansoni multidrug resistance protein 0.0012 0.0017 0.009
Echinococcus granulosus netrin receptor unc 5 0.0014 0.0026 0.0139
Loa Loa (eye worm) nuclear hormone receptor family member nhr-1 0.0011 0.0013 0.0022
Echinococcus granulosus mitogen activated protein kinase 3 0.0057 0.0173 0.0938
Echinococcus granulosus cyclic nucleotide gated cation channel 0.001 0.0011 0.0057
Brugia malayi larval opioid receptor 0.0033 0.0089 0.0949
Loa Loa (eye worm) hypothetical protein 0.0033 0.0089 0.0677
Mycobacterium tuberculosis NADPH-dependent mycothiol reductase Mtr 0.0068 0.0207 0.0197
Brugia malayi steroid hormone receptor 0.0011 0.0013 0.014
Trichomonas vaginalis lipid A export ATP-binding/permease protein msba, putative 0.0012 0.0017 0.0461
Echinococcus multilocularis serotonin receptor 0.0033 0.0089 0.046
Schistosoma mansoni Tr4/Tr2 (homologue) 0.0011 0.0013 0.0071
Trichomonas vaginalis voltage and ligand gated potassium channel, putative 0.0015 0.0028 0.0771
Echinococcus granulosus Peptidase C19 ubiquitin carboxyl terminal hydrolase 2 0.0073 0.0228 0.1238
Schistosoma mansoni neuropeptide receptor 0.0033 0.0089 0.0482
Schistosoma mansoni camp-dependent protein kinase regulatory chain 0.001 0.0011 0.0057
Trichomonas vaginalis multidrug resistance protein 1, 2, putative 0.0012 0.0017 0.0461
Mycobacterium leprae DIHYDROLIPOAMIDE DEHYDROGENASE LPD (LIPOAMIDE REDUCTASE (NADH)) (LIPOYL DEHYDROGENASE) (DIHYDROLIPOYL DEHYDROGENASE) (DIAPHORASE 0.0023 0.0056 0.0056
Trichomonas vaginalis ATP-binding cassette transporter, putative 0.0012 0.0017 0.0461
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0033 0.0089 0.0482
Echinococcus granulosus transcription factor btf3 0.0112 0.036 0.1959
Schistosoma mansoni camp-dependent protein kinase type I-beta regulatory subunit 0.001 0.0011 0.0057
Leishmania major cytochrome p450-like protein 0.0076 0.0236 0.6445
Echinococcus granulosus g protein coupled receptor 0.0033 0.0089 0.0482
Loa Loa (eye worm) hypothetical protein 0.0033 0.0089 0.0677
Loa Loa (eye worm) hypothetical protein 0.0033 0.0089 0.0677
Schistosoma mansoni dihydrolipoamide dehydrogenase 0.0023 0.0056 0.0305
Echinococcus granulosus 5'partial|ATP binding cassette sub family B 0.0012 0.0016 0.0088
Echinococcus granulosus neuropeptide receptor 0.0033 0.0089 0.0482
Loa Loa (eye worm) hypothetical protein 0.0075 0.0233 0.1927
Entamoeba histolytica ubiquitin carboxyl-terminal hydrolase domain containing protein 0.0073 0.0228 0.6139
Trichomonas vaginalis multidrug resistance protein 1, 2, putative 0.0012 0.0017 0.0461
Echinococcus granulosus ATP binding cassette subfamily B MDR:TAP 0.0012 0.0017 0.009
Loa Loa (eye worm) nuclear hormone receptor family member nhr-31 0.0011 0.0013 0.0022
Toxoplasma gondii cytochrome p450 superfamily protein 0.0022 0.0051 0.1076
Trypanosoma cruzi mitogen activated protein kinase 2, putative 0.0057 0.0173 0.4336
Brugia malayi Dopamine receptor protein 1 0.0033 0.0089 0.0949
Plasmodium falciparum glutathione reductase 0.0023 0.0056 0.1304
Toxoplasma gondii protease inhibitor PI2 0.0081 0.0255 0.6534
Mycobacterium ulcerans cytochrome P450 191A3 Cyp191A3 0.0022 0.0051 0.004
Trichomonas vaginalis lipid A export ATP-binding/permease protein msba, putative 0.0012 0.0017 0.0461
Echinococcus granulosus voltage gated potassium channel 0.0022 0.0052 0.0282
Mycobacterium ulcerans cytochrome P450 126A3 Cyp126A3 0.0022 0.0051 0.004
Brugia malayi Serotonin receptor 0.0033 0.0089 0.0949
Mycobacterium ulcerans beta-lactamase 0.0075 0.0233 0.0222
Plasmodium falciparum dihydrolipoyl dehydrogenase, apicoplast 0.0023 0.0056 0.1304
Schistosoma mansoni organic anion transporter 0.0119 0.0384 0.2089
Mycobacterium tuberculosis Probable hydrolase 0.0075 0.0233 0.0222
Onchocerca volvulus Dopamine\/Ecdysteroid receptor homolog 0.0033 0.0089 0.209
Echinococcus multilocularis somatostatin receptor 0.0033 0.0089 0.046
Giardia lamblia NADH oxidase lateral transfer candidate 0.0023 0.0056 0.2102
Echinococcus multilocularis neuropeptide s receptor 0.0033 0.0089 0.046
Loa Loa (eye worm) beta-lactamase 0.0075 0.0233 0.1927
Echinococcus multilocularis cyclic nucleotide gated cation channel 0.0015 0.0028 0.0128
Brugia malayi Nuclear hormone receptor-like 1 0.0011 0.0013 0.014
Schistosoma mansoni lamin 0.0056 0.0168 0.0914
Schistosoma mansoni peptide (FMRFamide/somatostatin)-like receptor 0.0033 0.0089 0.0482
Echinococcus granulosus potassium:sodium hyperpolarization activated 0.0015 0.0028 0.0151
Brugia malayi hypothetical protein 0.0033 0.0089 0.0949
Echinococcus multilocularis ATP binding cassette subfamily B (MDR:TAP) 0.0012 0.0017 0.0067
Loa Loa (eye worm) AGC/PKG protein kinase 0.0011 0.0012 0.0015
Schistosoma mansoni hypothetical protein 0.0544 0.1839 1
Echinococcus granulosus geminin 0.0544 0.1839 1
Trypanosoma cruzi ubiquitin carboxyl-terminal hydrolase, putative 0.0073 0.0228 0.581
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0011 0.0013 0.014
Echinococcus multilocularis cyclic nucleotide gated cation channel 0.001 0.0011 0.0034
Trichomonas vaginalis conserved hypothetical protein 0.0112 0.036 1
Loa Loa (eye worm) hypothetical protein 0.0055 0.0165 0.1336
Mycobacterium tuberculosis Probable lipase LipD 0.0075 0.0233 0.0222
Echinococcus multilocularis follistatin 0.0081 0.0255 0.1365
Echinococcus granulosus hypothetical protein 0.0033 0.0089 0.0482
Trichomonas vaginalis ATP-binding cassette transporter, putative 0.0012 0.0017 0.0461
Schistosoma mansoni follistatin 0.0081 0.0255 0.1385
Brugia malayi alpha keto acid dehydrogenase complex, E3 component, lipoamide dehydrogenase 0.0017 0.0035 0.0373
Treponema pallidum cysteinyl-tRNA synthetase 0.0043 0.0122 1
Brugia malayi hypothetical protein 0.0119 0.0384 0.4115
Trypanosoma brucei Lanosterol 14-alpha demethylase 0.0022 0.0051 0.1365
Loa Loa (eye worm) hypothetical protein 0.0033 0.0089 0.0677
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0033 0.0089 0.0482
Echinococcus granulosus death domain containing protein 0.0014 0.0026 0.0139
Loa Loa (eye worm) cytochrome P450 family protein 0.0076 0.0236 0.1955
Echinococcus granulosus cAMP dependent protein kinase type II regulatory 0.001 0.0011 0.0057
Trichomonas vaginalis importin beta-1, putative 0.0026 0.0066 0.1836
Loa Loa (eye worm) hypothetical protein 0.0033 0.0089 0.0677
Brugia malayi Kazal-type serine protease inhibitor domain containing protein 0.0081 0.0255 0.2728
Brugia malayi hypothetical protein 0.0033 0.0089 0.0949
Brugia malayi Nuclear hormone receptor family member nhr-3 0.0011 0.0013 0.014
Schistosoma mansoni neuropeptide F-like receptor 0.0033 0.0089 0.0482
Trichomonas vaginalis cAMP-dependent protein kinase regulatory subunit, putative 0.001 0.0011 0.0292
Echinococcus granulosus neuropeptides capa receptor 0.0033 0.0089 0.0482
Echinococcus multilocularis GTP binding nuclear protein Ran 0.0024 0.0058 0.0292
Echinococcus multilocularis biogenic amine (5HT) receptor 0.0033 0.0089 0.046
Echinococcus multilocularis potassium:sodium hyperpolarization activated 0.0015 0.0028 0.0128
Brugia malayi Nuclear hormone receptor family member nhr-1 0.0011 0.0013 0.014
Trichomonas vaginalis taga, putative 0.0012 0.0017 0.0461
Plasmodium vivax importin-beta 2, putative 0.0032 0.0087 0.2192
Toxoplasma gondii thioredoxin reductase 0.0068 0.0207 0.5271
Echinococcus granulosus snurportin 1 0.0347 0.1164 0.6329
Trichomonas vaginalis ABC transporter, half transporter, putative 0.0012 0.0017 0.0461
Loa Loa (eye worm) hypothetical protein 0.0033 0.0089 0.0677
Schistosoma mansoni ubiquitin-specific peptidase 8 (C19 family) 0.0073 0.0228 0.1238
Trichomonas vaginalis penicillin-binding protein, putative 0.0075 0.0233 0.6462
Brugia malayi N-terminal motif family protein 0.001 0.0011 0.0113
Loa Loa (eye worm) nuclear hormone receptor family member nhr-49 0.0011 0.0013 0.0022
Echinococcus multilocularis nuclear factor of activated T cells 5 0.0074 0.023 0.1232
Mycobacterium tuberculosis Probable esterase/lipase LipP 0.0075 0.0233 0.0222
Echinococcus multilocularis ubiquitin carboxyl terminal hydrolase 8 0.0073 0.0228 0.1217
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0011 0.0013 0.014
Echinococcus granulosus retinoic acid receptor rxr beta a 0.0011 0.0013 0.0071
Loa Loa (eye worm) hypothetical protein 0.0033 0.0089 0.0677
Leishmania major cysteinyl-tRNA synthetase, putative 0.0043 0.0122 0.319
Brugia malayi G-protein coupled receptor 0.0033 0.0089 0.0949
Onchocerca volvulus 0.0033 0.0089 0.209
Trypanosoma brucei cyclic nucleotide-binding domain containing protein, putative 0.001 0.0011 0.0244
Loa Loa (eye worm) hypothetical protein 0.0119 0.0384 0.324
Schistosoma mansoni nuclear hormone receptor nor-1/nor-2 0.0011 0.0013 0.0071
Echinococcus granulosus 7tm_1 domain containing protein 0.0033 0.0089 0.0482
Loa Loa (eye worm) hypothetical protein 0.0033 0.0089 0.0677
Schistosoma mansoni RAR-like nuclear receptor 0.0011 0.0013 0.0071
Echinococcus multilocularis Peptidase C19, ubiquitin carboxyl terminal hydrolase 2 0.0073 0.0228 0.1217
Schistosoma mansoni thyroid hormone receptor 0.0011 0.0013 0.0071
Trypanosoma cruzi importin beta-1 subunit, putative 0.0026 0.0066 0.1488
Echinococcus multilocularis allatostatin A receptor 0.0033 0.0089 0.046
Schistosoma mansoni hypothetical protein 0.0033 0.0089 0.0482
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0033 0.0089 0.0482
Schistosoma mansoni amine GPCR 0.0033 0.0089 0.0482
Mycobacterium ulcerans cytochrome P450 187A5 Cyp187A5 0.0022 0.0051 0.004
Mycobacterium tuberculosis Probable cytochrome P450 124 Cyp124 0.0022 0.0051 0.004
Mycobacterium ulcerans fusion of enoyl-CoA hydratase, EchA21 and lipase, LipE 0.0075 0.0233 0.0222
Trichomonas vaginalis abcb9, putative 0.0012 0.0017 0.0461
Loa Loa (eye worm) nuclear Hormone Receptor family member 0.0011 0.0013 0.0022
Schistosoma mansoni myosin xvIII 0.0033 0.0089 0.0482
Trypanosoma brucei protein kinase A regulatory subunit 0.001 0.0011 0.0244
Mycobacterium tuberculosis Possible cytochrome P450 135A1 Cyp135A1 0.0022 0.0051 0.004
Schistosoma mansoni hyperpolarization activated cyclic nucleotide-gated potassium channel 0.0015 0.0028 0.0151
Trichomonas vaginalis ABC transporter, putative 0.0012 0.0017 0.0461
Loa Loa (eye worm) hypothetical protein 0.0075 0.0233 0.1927
Schistosoma mansoni amine GPCR 0.0033 0.0089 0.0482
Mycobacterium tuberculosis Possible cytochrome P450 126 Cyp126 0.0022 0.0051 0.004
Echinococcus multilocularis rhodopsin orphan GPCR 0.0033 0.0089 0.046
Brugia malayi RNA, U transporter 1 0.0092 0.0292 0.3132
Onchocerca volvulus 0.0056 0.0168 0.4219
Mycobacterium tuberculosis Probable cytochrome P450 130 Cyp130 0.0022 0.0051 0.004
Trichomonas vaginalis voltage and ligand gated potassium channel, putative 0.001 0.0011 0.0292
Trichomonas vaginalis lipid A export ATP-binding/permease protein msba, putative 0.0012 0.0017 0.0461
Brugia malayi MAP kinase sur-1 0.0057 0.0173 0.1848
Brugia malayi hypothetical protein 0.0033 0.0089 0.0949
Brugia malayi sodium-independent organic anion transporter family protein 0.0119 0.0384 0.4115
Loa Loa (eye worm) agrin synaptic family protein 0.0081 0.0255 0.2117
Plasmodium falciparum multidrug resistance protein 1 0.0012 0.0017 0.0174
Loa Loa (eye worm) ICD-1 protein 0.0112 0.036 0.3033
Echinococcus multilocularis neuropeptide receptor A26 0.0033 0.0089 0.046
Schistosoma mansoni neuropathy target esterase/swiss cheese-related protein 0.001 0.0011 0.0057
Echinococcus multilocularis cyclic nucleotide gated cation channel 0.001 0.0011 0.0034
Echinococcus granulosus biogenic amine 5HT receptor 0.0033 0.0089 0.0482
Mycobacterium ulcerans lipase LipD 0.0075 0.0233 0.0222
Plasmodium falciparum thioredoxin reductase 0.0023 0.0056 0.1304
Brugia malayi G-protein-linked acetylcholine receptor protein 2, putative 0.0033 0.0089 0.0949
Brugia malayi neuropeptide F receptor 0.0033 0.0089 0.0949
Echinococcus granulosus importin subunit beta 1 0.0032 0.0087 0.0474
Mycobacterium tuberculosis NAD(P)H quinone reductase LpdA 0.0023 0.0056 0.0046
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0023 0.0056 0.1221
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0033 0.0089 0.0482
Entamoeba histolytica hypothetical protein 0.0026 0.0066 0.1441
Loa Loa (eye worm) hypothetical protein 0.0033 0.0089 0.0677
Schistosoma mansoni growth hormone secretagogue receptor 0.0033 0.0089 0.0482
Schistosoma mansoni amine GPCR 0.0033 0.0089 0.0482
Plasmodium vivax dihydrolipoyl dehydrogenase, mitochondrial, putative 0.0023 0.0056 0.1304
Trichomonas vaginalis lipid A export ATP-binding/permease protein msba, putative 0.0012 0.0017 0.0461
Echinococcus multilocularis COUP TF:Svp nuclear hormone receptor 0.0011 0.0013 0.0048
Loa Loa (eye worm) hypothetical protein 0.0033 0.0089 0.0677
Echinococcus granulosus intermediate filament protein 0.0056 0.0168 0.0914
Brugia malayi cytoplasmic intermediate filament protein 0.003 0.0079 0.0845
Echinococcus multilocularis serotonin receptor 0.0033 0.0089 0.046
Brugia malayi Protein kinase domain containing protein 0.0015 0.0027 0.0293
Schistosoma mansoni adenoreceptor 0.0033 0.0089 0.0482
Trichomonas vaginalis cAMP-dependent protein kinase type I-beta regulatory subunit, putative 0.001 0.0011 0.0292
Echinococcus granulosus dihydrolipoamide dehydrogenase 0.0023 0.0056 0.0305
Loa Loa (eye worm) hypothetical protein 0.0081 0.0255 0.2117
Loa Loa (eye worm) hypothetical protein 0.0014 0.0026 0.0131
Trichomonas vaginalis voltage and ligand gated potassium channel, putative 0.0071 0.0221 0.6128
Echinococcus multilocularis mitogen activated protein kinase 3 0.0057 0.0173 0.0917
Trypanosoma cruzi cytochrome P450, putative 0.0076 0.0236 0.6033
Loa Loa (eye worm) voltage and ligand gated potassium channel 0.0077 0.0238 0.1973
Onchocerca volvulus 0.0033 0.0089 0.209
Echinococcus granulosus multidrug resistance protein 1 0.0012 0.0017 0.009
Brugia malayi nuclear receptor NHR-88 0.0011 0.0013 0.014
Loa Loa (eye worm) hypothetical protein 0.0075 0.0233 0.1927
Echinococcus granulosus COUP TF:Svp nuclear hormone receptor 0.0011 0.0013 0.0071
Brugia malayi cAMP-dependent protein kinase regulatory chain, putative 0.001 0.0011 0.0113
Brugia malayi Voltage-gated potassium channel, HERG (KCNH2)-related. C. elegans unc-103 ortholog 0.0077 0.0238 0.255
Echinococcus granulosus g protein coupled receptor 0.0033 0.0089 0.0482
Wolbachia endosymbiont of Brugia malayi cysteinyl-tRNA synthetase 0.0043 0.0122 1
Schistosoma mansoni cysteinyl-tRNA synthetase 0.0043 0.0122 0.0664
Brugia malayi Cytochrome P450 family protein 0.0076 0.0236 0.2528
Schistosoma mansoni serine/threonine protein kinase 0.0011 0.0012 0.0067
Schistosoma mansoni thyroid hormone receptor 0.0011 0.0013 0.0071
Trypanosoma cruzi Lanosterol 14-alpha demethylase 0.0022 0.0051 0.1076
Onchocerca volvulus 0.0033 0.0089 0.209
Trypanosoma cruzi hypothetical protein, conserved 0.0075 0.0233 0.5949
Trichomonas vaginalis ATP-binding cassette transporter, putative 0.0012 0.0017 0.0461
Mycobacterium tuberculosis Probable esterase LipL 0.0075 0.0233 0.0222
Loa Loa (eye worm) hypothetical protein 0.0033 0.0089 0.0677
Brugia malayi Unidentified vitellogenin-linked transcript protein 6, putative 0.0033 0.0089 0.0949
Plasmodium falciparum importin beta, putative 0.0032 0.0087 0.2192
Echinococcus granulosus ATP binding cassette subfamily B MDR:TAP 0.0012 0.0017 0.009
Mycobacterium tuberculosis Probable cytochrome P450 123 Cyp123 0.0022 0.0051 0.004
Loa Loa (eye worm) neuropeptide F receptor 0.0033 0.0089 0.0677
Schistosoma mansoni multidrug resistance protein 0.0012 0.0017 0.009
Echinococcus granulosus rhodopsin orphan GPCR 0.0033 0.0089 0.0482
Schistosoma mansoni cytochrome P450 0.0022 0.0051 0.0276
Echinococcus granulosus beta LACTamase domain containing family member 0.0075 0.0233 0.1266
Trichomonas vaginalis D-aminoacylase, putative 0.0075 0.0233 0.6462
Onchocerca volvulus 0.0033 0.0089 0.209
Loa Loa (eye worm) hypothetical protein 0.0033 0.0089 0.0677
Mycobacterium ulcerans cytochrome P450 108B4 Cyp108B4 0.0022 0.0051 0.004
Brugia malayi Immunoglobulin I-set domain containing protein 0.0014 0.0026 0.0274
Echinococcus granulosus tm gpcr rhodopsin 0.0033 0.0089 0.0482
Schistosoma mansoni peptide (FMRFamide/somatostatin)-like receptor 0.0033 0.0089 0.0482
Loa Loa (eye worm) cyclic-nucleotide gated cation channel 0.0015 0.0028 0.015
Brugia malayi RE15519p 0.0033 0.0089 0.0949
Schistosoma mansoni neuropathy target esterase/swiss cheese-related protein 0.001 0.0011 0.0057
Echinococcus multilocularis thyrotropin releasing hormone receptor 0.0033 0.0089 0.046
Echinococcus granulosus neuropeptide receptor 0.0033 0.0089 0.0482
Schistosoma mansoni netrin receptor unc5 0.0014 0.0026 0.0139
Loa Loa (eye worm) cytoplasmic intermediate filament protein 0.003 0.0079 0.0593
Trichomonas vaginalis conserved hypothetical protein 0.001 0.0011 0.0292
Schistosoma mansoni camp-dependent protein kinase type II-alpha regulatory subunit 0.001 0.0011 0.0057
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0033 0.0089 0.0482
Echinococcus granulosus tachykinin peptides receptor 99D 0.0033 0.0089 0.0482
Onchocerca volvulus Putative organic anion transporter 0.0119 0.0384 1
Loa Loa (eye worm) hypothetical protein 0.0012 0.0017 0.0053
Schistosoma mansoni peptide (allatostatin)-like receptor 0.0033 0.0089 0.0482
Schistosoma mansoni amine GPCR 0.0033 0.0089 0.0482
Brugia malayi GTP-binding nuclear protein RAN/TC4 0.0024 0.0058 0.0619
Mycobacterium ulcerans cytochrome P450 188A3 Cyp188A3 0.0022 0.0051 0.004
Loa Loa (eye worm) hypothetical protein 0.0015 0.0028 0.015
Echinococcus granulosus sex peptide receptor 0.0033 0.0089 0.0482
Loa Loa (eye worm) hypothetical protein 0.0011 0.0013 0.0022
Schistosoma mansoni hypothetical protein 0.0544 0.1839 1
Schistosoma mansoni biogenic amine (5HT) receptor 0.0033 0.0089 0.0482
Loa Loa (eye worm) hypothetical protein 0.0033 0.0089 0.0677
Trypanosoma brucei Flagellar Member 6 0.001 0.0011 0.0244
Echinococcus granulosus Solute carrier organic anion transporter family 0.0119 0.0384 0.2089
Mycobacterium leprae conserved hypothetical protein 0.0075 0.0233 0.0233
Loa Loa (eye worm) nuclear hormone receptor family member nhr-14 0.0011 0.0013 0.0022
Echinococcus multilocularis agrin 0.0081 0.0255 0.1365
Brugia malayi follicle stimulating hormone receptor 0.0279 0.0933 1
Brugia malayi sodium-independent organic anion transporter family protein 0.0119 0.0384 0.4115
Toxoplasma gondii pyruvate dehydrogenase complex subunit PDH-E3II 0.0023 0.0056 0.1221
Echinococcus multilocularis hyperpolarization activated cyclic 0.0015 0.0028 0.0128
Brugia malayi hypothetical protein 0.0033 0.0089 0.0949
Loa Loa (eye worm) melatonin receptor type 1A 0.0033 0.0089 0.0677
Onchocerca volvulus Neuropeptide F receptor homolog 0.0033 0.0089 0.209
Trypanosoma brucei dihydrolipoyl dehydrogenase 0.0023 0.0056 0.1517
Loa Loa (eye worm) kazal-type serine protease inhibitor domain-containing protein 0.0081 0.0255 0.2117
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0023 0.0056 0.1221
Loa Loa (eye worm) hypothetical protein 0.0032 0.0087 0.0665
Echinococcus granulosus allatostatin A receptor 0.0033 0.0089 0.0482
Echinococcus granulosus cyclic nucleotide gated cation channel alpha 3 0.0015 0.0028 0.0151
Schistosoma mansoni hypothetical protein 0.0033 0.0089 0.0482
Plasmodium vivax dihydrolipoyl dehydrogenase, apicoplast, putative 0.0023 0.0056 0.1304
Echinococcus granulosus neuropeptide receptor A26 0.0033 0.0089 0.0482
Entamoeba histolytica Ran family GTPase 0.0024 0.0058 0.1199
Mycobacterium ulcerans cytochrome P450 51B1 Cyp51B1 0.0022 0.0051 0.004
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0073 0.0228 0.6317
Schistosoma mansoni biogenic amine (5HT) receptor 0.0033 0.0089 0.0482
Echinococcus granulosus ATP binding cassette subfamily B MDR:TAP 0.0012 0.0017 0.009
Mycobacterium ulcerans dihydrolipoamide dehydrogenase 0.0023 0.0056 0.0046
Loa Loa (eye worm) hypothetical protein 0.0119 0.0384 0.324
Onchocerca volvulus 0.0033 0.0089 0.209
Echinococcus granulosus mitogen activated protein kinase 0.0057 0.0173 0.0938
Brugia malayi beta-lactamase 0.0075 0.0233 0.2494
Trypanosoma brucei hypothetical protein, conserved 0.0075 0.0233 0.6444
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0073 0.0228 0.6317
Schistosoma mansoni histamine-responsive GPCR (AAF21638) 0.0033 0.0089 0.0482
Trichomonas vaginalis cysteinyl-tRNA synthetase, putative 0.0043 0.0122 0.339
Echinococcus multilocularis 0.0022 0.0051 0.0253
Schistosoma mansoni nuclear receptor 2DBD-gamma 0.0011 0.0013 0.0071
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0033 0.0089 0.0482
Schistosoma mansoni hypothetical protein 0.0347 0.1164 0.6329
Echinococcus multilocularis cyclic nucleotide gated cation channel alpha 3 0.0015 0.0028 0.0128
Echinococcus multilocularis cytoplasmic intermediate filament protein 0.0027 0.0069 0.0351
Echinococcus multilocularis G-protein coupled receptor, putative 0.0033 0.0089 0.046
Plasmodium falciparum GTP-binding nuclear protein RAN/TC4 0.0024 0.0058 0.1352
Echinococcus multilocularis ATP binding cassette subfamily B (MDR:TAP) 0.0012 0.0017 0.0067
Echinococcus multilocularis G protein coupled 5 hydroxytryptamine receptor 0.0033 0.0089 0.046
Echinococcus multilocularis cAMP dependent protein kinase type I beta 0.001 0.0011 0.0034
Leishmania major hypothetical protein, conserved 0.0075 0.0233 0.6355
Echinococcus granulosus fmrfamide receptor 0.0033 0.0089 0.0482
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0011 0.0013 0.0048
Trichomonas vaginalis esterase, putative 0.0075 0.0233 0.6462
Echinococcus granulosus GTP binding nuclear protein Ran 0.0024 0.0058 0.0314
Giardia lamblia Kinase, CMGC MAPK 0.0057 0.0173 0.7464
Trichomonas vaginalis multidrug resistance protein 1, 2, putative 0.0012 0.0017 0.0461
Echinococcus multilocularis FTZ F1 alpha 0.0011 0.0013 0.0048
Schistosoma mansoni camp-dependent protein kinase type I-beta regulatory subunit 0.001 0.0011 0.0057
Trichomonas vaginalis conserved hypothetical protein 0.0073 0.0228 0.6317
Trichomonas vaginalis CMGC family protein kinase 0.0057 0.0173 0.4789
Trichomonas vaginalis ATP-binding cassette transporter, putative 0.0008 0.0004 0.012
Brugia malayi Voltage-gated potassium channel, EAG (KCNH1)-related. C. elegans egl-2 ortholog 0.0022 0.0052 0.0556
Mycobacterium tuberculosis Possible penicillin-binding protein 0.0479 0.1617 0.1608
Echinococcus granulosus potassium voltage gated channel subfamily H 0.0022 0.0052 0.0282
Mycobacterium tuberculosis Probable oxidoreductase 0.0023 0.0056 0.0046
Schistosoma mansoni neuropeptide f receptor 76f 0.0033 0.0089 0.0482
Trichomonas vaginalis ABC transporter, half transporter, putative 0.0012 0.0017 0.0461
Echinococcus granulosus g-protein coupled receptor 0.0033 0.0089 0.0482
Trichomonas vaginalis CMGC family protein kinase 0.0057 0.0173 0.4789
Trypanosoma brucei mitogen activated protein kinase 4, putative 0.0057 0.0173 0.4763
Onchocerca volvulus Putative organic anion transporter 0.0119 0.0384 1
Mycobacterium ulcerans cytochrome P450 124A1, Cyp124A1 0.0022 0.0051 0.004
Leishmania major basic transcription factor 3a, putative 0.0112 0.036 1
Brugia malayi AKH receptor 0.0033 0.0089 0.0949
Brugia malayi GnHR receptor homolog 0.0033 0.0089 0.0949
Echinococcus multilocularis dro:myosuppressin receptor 0.0033 0.0089 0.046
Brugia malayi Kazal-type serine protease inhibitor domain containing protein 0.0081 0.0255 0.2728
Toxoplasma gondii cysteine-tRNA synthetase (CysRS) 0.0043 0.0122 0.2987
Mycobacterium tuberculosis Cytochrome P450 51 Cyp51 (CYPL1) (P450-L1A1) (sterol 14-alpha demethylase) (lanosterol 14-alpha demethylase) (P450-14DM) 0.0022 0.0051 0.004
Trypanosoma brucei importin beta-1 subunit, putative 0.0032 0.0087 0.2382
Schistosoma mansoni peptide (allatostatin/somatostatin)-like receptor 0.0033 0.0089 0.0482
Onchocerca volvulus 0.0012 0.0017 0.0162
Loa Loa (eye worm) immunoglobulin I-set domain-containing protein 0.0014 0.0026 0.0131
Echinococcus multilocularis thyroid hormone receptor alpha 0.0011 0.0013 0.0048
Loa Loa (eye worm) hypothetical protein 0.0033 0.0089 0.0677
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0011 0.0013 0.0071
Echinococcus granulosus rhodopsin orphan GPCR 0.0033 0.0089 0.0482
Trypanosoma cruzi transcription factor btf3, putative 0.0112 0.036 0.9361
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0033 0.0089 0.0482
Schistosoma mansoni transcription factor btf3 0.0112 0.036 0.1959
Mycobacterium tuberculosis Probable cytochrome P450 141 Cyp141 0.0022 0.0051 0.004
Loa Loa (eye worm) hypothetical protein 0.0033 0.0089 0.0677
Echinococcus granulosus cyclic nucleotide gated cation channel 0.0015 0.0028 0.0151
Trichomonas vaginalis multidrug resistance protein 1, 2, putative 0.0012 0.0017 0.0461
Brugia malayi Dopamine receptor protein 1, putative (partial) 0.0033 0.0089 0.0949
Echinococcus granulosus ubiquitin specific protease 41 0.0073 0.0228 0.1238
Brugia malayi secreted modular calcium-binding protein 1 0.0081 0.0255 0.2728
Echinococcus multilocularis Solute carrier organic anion transporter family 0.0119 0.0384 0.2071
Echinococcus granulosus ankyrin repeat and death domain containing protein 0.0014 0.0026 0.0139
Loa Loa (eye worm) hypothetical protein 0.0033 0.0089 0.0677
Toxoplasma gondii ABC transporter transmembrane region domain-containing protein 0.0012 0.0017 0.0162
Schistosoma mansoni neuropeptide F-like receptor 0.0033 0.0089 0.0482
Leishmania major cytochrome p450-like protein 0.0022 0.0051 0.1149
Loa Loa (eye worm) nucleolar RNA-associated protein alpha 0.0347 0.1164 1
Trichomonas vaginalis abcb9, putative 0.0012 0.0017 0.0461
Onchocerca volvulus Bile acid receptor homolog 0.0011 0.0013 0.0067
Loa Loa (eye worm) hypothetical protein 0.0033 0.0089 0.0677
Loa Loa (eye worm) hypothetical protein 0.0011 0.0013 0.0022
Loa Loa (eye worm) multidrug resistance protein 3 0.0012 0.0017 0.0053
Leishmania major dihydrolipoamide dehydrogenase, putative 0.0023 0.0056 0.1304
Echinococcus multilocularis importin subunit beta 1 0.0032 0.0087 0.0452
Loa Loa (eye worm) sodium-independent organic anion transporter 0.0119 0.0384 0.324
Echinococcus multilocularis neuropeptides capa receptor 0.0033 0.0089 0.046
Mycobacterium ulcerans dihydrolipoamide dehydrogenase, LpdB 0.0023 0.0056 0.0046
Mycobacterium ulcerans flavoprotein disulfide reductase 0.0023 0.0056 0.0046
Schistosoma mansoni cyclic-nucleotide-gated cation channel 0.0015 0.0028 0.0151
Echinococcus granulosus multidrug resistance protein 1 0.0008 0.0004 0.0023
Echinococcus multilocularis g protein linked acetylcholine receptor gar 2a 0.0033 0.0089 0.046
Onchocerca volvulus 0.0075 0.0233 0.5949
Echinococcus granulosus Nuclear hormone receptor family member nhr 41 0.0011 0.0013 0.0071
Echinococcus multilocularis Ankyrin 0.0015 0.0026 0.0118
Loa Loa (eye worm) hypothetical protein 0.0073 0.0228 0.1882
Trypanosoma brucei trypanothione reductase 0.0068 0.0207 0.5737
Mycobacterium ulcerans cytochrome P450 136A2 Cyp136A2 0.0022 0.0051 0.004
Loa Loa (eye worm) hypothetical protein 0.0033 0.0089 0.0677
Mycobacterium tuberculosis Probable cytochrome P450 144 Cyp144 0.0022 0.0051 0.004
Echinococcus multilocularis organic anion transporting polypeptide 30B 0.0119 0.0384 0.2071
Mycobacterium ulcerans cytochrome P450 187A4 Cyp187A4 0.0022 0.0051 0.004
Echinococcus multilocularis expressed protein 0.0081 0.0255 0.1365
Loa Loa (eye worm) hypothetical protein 0.0119 0.0384 0.324
Echinococcus multilocularis g protein coupled receptor 0.0033 0.0089 0.046
Mycobacterium ulcerans cytochrome P450 105Q4 Cyp105Q4 0.0022 0.0051 0.004
Brugia malayi nuclear hormone receptor 0.0011 0.0013 0.014
Schistosoma mansoni voltage-gated potassium channel 0.0012 0.0017 0.0094
Brugia malayi dihydrolipoyl dehydrogenase, mitochondrial precursor, putative 0.0023 0.0056 0.0602
Treponema pallidum NADH oxidase 0.0023 0.0056 0.4089
Trichomonas vaginalis penicillin-binding protein, putative 0.0075 0.0233 0.6462
Brugia malayi Death domain containing protein 0.0014 0.0026 0.0274
Mycobacterium leprae Conserved hypothetical protein 0.0022 0.0051 0.0051
Leishmania major dihydrolipoamide dehydrogenase, putative 0.0023 0.0056 0.1304
Echinococcus granulosus cyclic nucleotide gated cation channel 0.0015 0.0028 0.0151
Chlamydia trachomatis dihydrolipoyl dehydrogenase 0.0023 0.0056 0.4089
Entamoeba histolytica transcription factor BTF3, putative 0.0112 0.036 1
Trichomonas vaginalis ABC transporter, putative 0.0012 0.0017 0.0461
Echinococcus multilocularis snurportin 1 0.0347 0.1164 0.632
Schistosoma mansoni cyclic-nucleotide-gated cation channel 0.0015 0.0028 0.0151
Echinococcus granulosus agrin 0.0081 0.0255 0.1385
Echinococcus multilocularis expressed conserved protein 0.0011 0.0012 0.0044
Trypanosoma brucei cAMP response protein 1, putative 0.001 0.0011 0.0244
Schistosoma mansoni retinoic acid receptor RXR 0.0011 0.0013 0.0071
Echinococcus granulosus g protein coupled receptor 0.0033 0.0089 0.0482
Brugia malayi Serotonin receptor 0.0033 0.0089 0.0949
Mycobacterium ulcerans cytochrome P450 142A3 Cyp142A3 0.0022 0.0051 0.004
Trypanosoma cruzi trypanothione reductase, putative 0.0068 0.0207 0.5271
Toxoplasma gondii NAC domain-containing protein 0.0112 0.036 0.9361
Loa Loa (eye worm) hypothetical protein 0.0033 0.0089 0.0677
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0033 0.0089 0.0482
Loa Loa (eye worm) hypothetical protein 0.0054 0.0161 0.1306
Mycobacterium tuberculosis Probable cytochrome P450 128 Cyp128 0.0022 0.0051 0.004
Loa Loa (eye worm) hypothetical protein 0.0011 0.0013 0.0022
Loa Loa (eye worm) intermediate filament protein 0.0056 0.0168 0.1367
Echinococcus granulosus g protein linked acetylcholine receptor gar 2a 0.0033 0.0089 0.0482
Brugia malayi hypothetical protein 0.0033 0.0089 0.0949
Loa Loa (eye worm) hypothetical protein 0.0043 0.0122 0.0968
Brugia malayi Dopamine receptor protein 2 0.0033 0.0089 0.0949
Schistosoma mansoni smdr2 0.0012 0.0017 0.009
Loa Loa (eye worm) hypothetical protein 0.0033 0.0089 0.0677
Schistosoma mansoni serine/threonine protein kinase 0.0057 0.0173 0.0938
Mycobacterium tuberculosis Probable cytochrome P450 136 Cyp136 0.0022 0.0051 0.004
Brugia malayi Kazal-type serine protease inhibitor domain containing protein 0.0081 0.0255 0.2728
Trichomonas vaginalis abcb9, putative 0.0012 0.0017 0.0461
Trypanosoma cruzi Lanosterol 14-alpha demethylase 0.0022 0.0051 0.1076
Echinococcus granulosus tm gpcr rhodopsin 0.0033 0.0089 0.0482
Trichomonas vaginalis lipid A export ATP-binding/permease protein msba, putative 0.0012 0.0017 0.0461
Brugia malayi cysteinyl tRNA synthetase protein 1 0.0043 0.0122 0.1308
Mycobacterium leprae Probable lipase LipE 0.0075 0.0233 0.0233
Echinococcus granulosus neuropeptide s receptor 0.0033 0.0089 0.0482
Leishmania major lanosterol 14-alpha-demethylase, putative 0.0022 0.0051 0.1149
Loa Loa (eye worm) hypothetical protein 0.0033 0.0089 0.0677
Trichomonas vaginalis CMGC family protein kinase 0.0057 0.0173 0.4789
Schistosoma mansoni amine GPCR 0.0033 0.0089 0.0482
Brugia malayi cytochrome P450 0.0022 0.0051 0.0543
Schistosoma mansoni voltage-gated potassium channel 0.0084 0.0262 0.1426
Echinococcus multilocularis fmrfamide receptor 0.0033 0.0089 0.046
Brugia malayi multidrug resistance protein 3 0.0012 0.0017 0.0178
Loa Loa (eye worm) TYRA-2 protein 0.0033 0.0089 0.0677
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0033 0.0089 0.0482
Toxoplasma gondii protein kinase G AGC kinase family member PKG 0.0011 0.0012 0.0048
Echinococcus multilocularis mitogen activated protein kinase 0.0057 0.0173 0.0917
Echinococcus multilocularis neuropeptides capa receptor 0.0033 0.0089 0.046
Brugia malayi Egg laying defective protein 4 0.0011 0.0012 0.0132
Brugia malayi ABC transporter family protein 0.0012 0.0017 0.0178
Trypanosoma brucei protein kinase, putative 0.0057 0.0173 0.4763
Onchocerca volvulus 0.0119 0.0384 1
Schistosoma mansoni hyperpolarization activated cyclic nucleotide-gated potassium channel 0.0015 0.0028 0.0151
Leishmania major protein kinase, putative 0.0011 0.0012 0.0051
Echinococcus granulosus 7TM GPCR rhodopsin 0.0033 0.0089 0.0482
Onchocerca volvulus 0.0119 0.0384 1
Loa Loa (eye worm) hypothetical protein 0.0033 0.0089 0.0677
Onchocerca volvulus 0.0119 0.0384 1
Trichomonas vaginalis ABC transporter, putative 0.0012 0.0017 0.0461
Trypanosoma cruzi cytochrome p450-like protein, putative 0.0022 0.0051 0.1076
Toxoplasma gondii Kazal-type serine protease inhibitor domain-containing protein 0.0081 0.0255 0.6534
Trypanosoma cruzi GTP-binding nuclear protein rtb2, putative 0.0024 0.0058 0.1265
Loa Loa (eye worm) CMGC/MAPK/ERK1 protein kinase 0.0057 0.0173 0.1405
Loa Loa (eye worm) follicle stimulating hormone receptor 0.0279 0.0933 0.8003
Loa Loa (eye worm) hypothetical protein 0.0011 0.0013 0.0022
Echinococcus multilocularis peptide (allatostatin:somatostatin) 0.0033 0.0089 0.046
Echinococcus granulosus multidrug resistance protein 1 0.0008 0.0004 0.0023
Echinococcus multilocularis g protein coupled receptor 0.0033 0.0089 0.046
Echinococcus granulosus FTZ F1 nuclear receptor protein 0.0011 0.0013 0.0071
Schistosoma mansoni voltage-gated potassium channel 0.0022 0.0052 0.0282
Brugia malayi intermediate filament protein 0.0056 0.0168 0.1801
Mycobacterium tuberculosis Probable transmembrane multidrug efflux pump 0.0012 0.0017 0.0006
Loa Loa (eye worm) hypothetical protein 0.0033 0.0089 0.0677
Echinococcus granulosus dro:myosuppressin receptor 0.0033 0.0089 0.0482
Trypanosoma cruzi cytochrome P450, putative 0.0076 0.0236 0.6033
Loa Loa (eye worm) ATP-binding cassette sub-family B member 2 0.0012 0.0017 0.0053
Trichomonas vaginalis mercuric reductase, putative 0.0023 0.0056 0.1559
Trichomonas vaginalis Importin beta-1 subunit, putative 0.0026 0.0066 0.1836
Schistosoma mansoni hypothetical protein 0.0033 0.0089 0.0482
Loa Loa (eye worm) hypothetical protein 0.0075 0.0233 0.1927
Loa Loa (eye worm) gonadotropin-releasing hormone receptor 2 0.0033 0.0089 0.0677
Echinococcus multilocularis 7TM GPCR, rhodopsin 0.0033 0.0089 0.046
Echinococcus granulosus FTZ F1 alpha 0.0011 0.0013 0.0071
Brugia malayi Cyclic-nucleotide gated cation channel 0.0015 0.0028 0.0298
Brugia malayi ecdysteroid receptor 0.0011 0.0013 0.014
Echinococcus multilocularis g protein coupled receptor 0.0033 0.0089 0.046
Loa Loa (eye worm) cytochrome P450 family protein 0.0022 0.0051 0.0349
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0023 0.0056 0.1221
Echinococcus granulosus rhodopsin orphan GPCR 0.0033 0.0089 0.0482
Brugia malayi hypothetical protein 0.0033 0.0089 0.0949
Loa Loa (eye worm) cytochrome P450 family protein 0.0076 0.0236 0.1955
Loa Loa (eye worm) hypothetical protein 0.0011 0.0013 0.0022
Trichomonas vaginalis multidrug resistance protein 1, 2, putative 0.0012 0.0017 0.0461
Brugia malayi Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain containing protein 0.0017 0.0035 0.0373
Loa Loa (eye worm) hypothetical protein 0.0033 0.0089 0.0677
Brugia malayi putative neuropeptide receptor NPR1 0.0033 0.0089 0.0949
Brugia malayi Cyclic-nucleotide gated cation channel, C. elegans tax-4 ortholog 0.001 0.0011 0.0113
Echinococcus multilocularis multidrug resistance protein 1 0.0012 0.0017 0.0067
Echinococcus granulosus ecdysone induced protein 78C 0.0011 0.0013 0.0071
Loa Loa (eye worm) neuropeptide F receptor 0.0033 0.0089 0.0677
Onchocerca volvulus 0.0119 0.0384 1
Loa Loa (eye worm) hypothetical protein 0.0012 0.0017 0.0053
Echinococcus granulosus neuropeptide Y receptor 0.0033 0.0089 0.0482
Brugia malayi Nuclear hormone receptor family member nhr-31 0.0011 0.0013 0.014
Loa Loa (eye worm) hypothetical protein 0.0033 0.0089 0.0677
Echinococcus multilocularis FTZ F1 nuclear receptor protein 0.0011 0.0013 0.0048
Trichomonas vaginalis ran, putative 0.0024 0.0058 0.1605
Echinococcus multilocularis ATP binding cassette subfamily B (MDR:TAP) 0.0012 0.0017 0.0067
Loa Loa (eye worm) nuclear hormone receptor family member nhr-40 0.0011 0.0013 0.0022
Onchocerca volvulus Protein ultraspiracle homolog 0.0011 0.0013 0.0067
Schistosoma mansoni cyclic-nucleotide-gated cation channel 0.001 0.0011 0.0057
Mycobacterium tuberculosis Possible cytochrome P450 135B1 Cyp135B1 0.0022 0.0051 0.004
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0033 0.0089 0.0482
Leishmania major trypanothione reductase 0.0068 0.0207 0.5631
Echinococcus granulosus lamin dm0 0.0056 0.0168 0.0914
Schistosoma mansoni hypothetical protein 0.0033 0.0089 0.0482
Schistosoma mansoni nuclear hormone receptor 0.0011 0.0013 0.0071
Echinococcus granulosus ATP binding cassette subfamily B MDR:TAP 0.0012 0.0017 0.009
Echinococcus multilocularis rhodopsin orphan GPCR 0.0033 0.0089 0.046
Brugia malayi Nuclear hormone receptor family member nhr-41 0.0011 0.0013 0.014
Onchocerca volvulus 0.0056 0.0168 0.4219
Schistosoma mansoni hyperpolarization activated cyclic nucleotide-gated potassium channel 0.001 0.0011 0.0057
Echinococcus granulosus multidrug resistance protein 1 0.0012 0.0017 0.009
Plasmodium vivax thioredoxin reductase, putative 0.0068 0.0207 0.5631
Onchocerca volvulus Putative organic anion transporter 0.0119 0.0384 1
Trichomonas vaginalis multidrug resistance protein 1, 2, putative 0.0012 0.0017 0.0461
Echinococcus multilocularis tachykinin peptides receptor 99D 0.0033 0.0089 0.046
Brugia malayi Ubiquitin carboxyl-terminal hydrolase family protein 0.0073 0.0228 0.2438
Echinococcus granulosus rhodopsin orphan GPCR 0.0033 0.0089 0.0482
Toxoplasma gondii CMGC kinase, MAPK family (ERK) MAPK-1 0.0057 0.0173 0.4336
Schistosoma mansoni opsin-like receptor 0.0033 0.0089 0.0482
Echinococcus multilocularis cGMP dependent protein kinase 1 0.0011 0.0012 0.0044
Mycobacterium tuberculosis Probable cytochrome P450 139 Cyp139 0.0022 0.0051 0.004
Mycobacterium tuberculosis Probable cytochrome P450 monooxygenase 142 Cyp142 0.0022 0.0051 0.004
Echinococcus multilocularis thioredoxin glutathione reductase 0.0068 0.0207 0.1107
Mycobacterium ulcerans cytochrome P450 185A4 Cyp185A4 0.0076 0.0236 0.0226
Onchocerca volvulus 0.0011 0.0013 0.0067
Toxoplasma gondii Kazal-type serine protease inhibitor domain-containing protein 0.0081 0.0255 0.6534
Plasmodium vivax GTP-binding nuclear protein RAN/TC4, putative 0.0024 0.0058 0.1352
Brugia malayi ORL1-like opioid receptor 0.0033 0.0089 0.0949
Schistosoma mansoni alpha-1 adrenergic receptor 0.0033 0.0089 0.0482
Mycobacterium ulcerans cytochrome P450 125A7 Cyp125A7 0.0022 0.0051 0.004
Toxoplasma gondii NADPH-glutathione reductase 0.0023 0.0056 0.1221
Loa Loa (eye worm) hypothetical protein 0.0033 0.0089 0.0677
Schistosoma mansoni muscarinic acetylcholine (GAR) receptor 0.0033 0.0089 0.0482
Schistosoma mansoni opsin-like receptor 0.0033 0.0089 0.0482
Echinococcus multilocularis growth hormone secretagogue receptor type 1 0.0033 0.0089 0.046
Trypanosoma brucei cAMP binding protein, putative 0.001 0.0011 0.0244
Mycobacterium ulcerans cytochrome P450 143A4 Cyp143A4 0.0022 0.0051 0.004
Brugia malayi Tachykinin-like peptides receptor 99D 0.0033 0.0089 0.0949
Loa Loa (eye worm) hypothetical protein 0.0027 0.0069 0.0504
Loa Loa (eye worm) hypothetical protein 0.0033 0.0089 0.0677
Echinococcus multilocularis neuropeptide FF receptor 2 0.0033 0.0089 0.046
Loa Loa (eye worm) hypothetical protein 0.0033 0.0089 0.0677
Mycobacterium tuberculosis Cysteine:1D-myo-inosityl 2-amino-2-deoxy--D-glucopyranoside ligase MshC 0.2926 1 1
Trypanosoma brucei dihydrolipoamide dehydrogenase 0.0023 0.0056 0.1517
Trichomonas vaginalis lipid A export ATP-binding/permease protein msba, putative 0.0012 0.0017 0.0461
Loa Loa (eye worm) thioredoxin reductase 0.0068 0.0207 0.1708
Echinococcus multilocularis rhodopsin orphan GPCR 0.0033 0.0089 0.046
Schistosoma mansoni biogenic amine receptor 0.0033 0.0089 0.0482
Onchocerca volvulus 0.0033 0.0089 0.209
Echinococcus granulosus thyrotropin releasing hormone receptor 0.0033 0.0089 0.0482
Loa Loa (eye worm) hypothetical protein 0.0011 0.0013 0.0022
Trichomonas vaginalis conserved hypothetical protein 0.0112 0.036 1
Echinococcus multilocularis musashi 0.0056 0.0168 0.0893
Trypanosoma cruzi dihydrolipoyl dehydrogenase, putative 0.0023 0.0056 0.1221
Mycobacterium ulcerans cytochrome P450 189A7 Cyp189A7 0.0022 0.0051 0.004
Plasmodium falciparum cysteine--tRNA ligase 0.0043 0.0122 0.319
Echinococcus granulosus ubiquitin carboxyl terminal hydrolase 8 0.0073 0.0228 0.1238
Loa Loa (eye worm) G-protein coupled receptor 0.0033 0.0089 0.0677
Loa Loa (eye worm) hypothetical protein 0.0026 0.0065 0.0474
Onchocerca volvulus 0.0033 0.0089 0.209
Loa Loa (eye worm) hypothetical protein 0.0033 0.0089 0.0677
Loa Loa (eye worm) hypothetical protein 0.0033 0.0089 0.0677
Brugia malayi Nuclear hormone receptor family member nhr-49 0.0011 0.0013 0.014
Echinococcus multilocularis Nuclear hormone receptor family member nhr 41 0.0011 0.0013 0.0048
Leishmania major p-glycoprotein 0.0012 0.0017 0.0174
Toxoplasma gondii GTP-binding nuclear protein ran/tc4 0.0024 0.0058 0.1265
Schistosoma mansoni ran 0.0024 0.0058 0.0314
Echinococcus granulosus g protein linked acetylcholine receptor gar 2a 0.0033 0.0089 0.0482
Echinococcus multilocularis ankyrin repeat and death domain containing protein 0.0014 0.0026 0.0116
Mycobacterium tuberculosis Probable conserved lipoprotein 0.0075 0.0233 0.0222
Mycobacterium tuberculosis Probable soluble pyridine nucleotide transhydrogenase SthA (STH) (NAD(P)(+) transhydrogenase [B-specific]) (nicotinamide nucleot 0.0023 0.0056 0.0046
Echinococcus granulosus somatostatin receptor 0.0033 0.0089 0.0482
Echinococcus granulosus pyroglutamylated rfamide peptide receptor 0.0033 0.0089 0.0482
Loa Loa (eye worm) hypothetical protein 0.0033 0.0089 0.0677
Mycobacterium ulcerans cytochrome P450 123A3 Cyp123A3 0.0022 0.0051 0.004
Mycobacterium tuberculosis Cytochrome P450 121 Cyp121 0.0022 0.0051 0.004
Plasmodium vivax hypothetical protein, conserved 0.0075 0.0233 0.6355
Schistosoma mansoni photoreceptor-specific nuclear receptor related 0.0011 0.0013 0.0071
Schistosoma mansoni intermediate filament proteins 0.0056 0.0168 0.0914
Loa Loa (eye worm) nuclear hormone receptor family member nhr-41 0.0011 0.0013 0.0022
Echinococcus granulosus orexin receptor type 2 0.0033 0.0089 0.0482
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0011 0.0013 0.014
Trypanosoma cruzi cysteinyl-tRNA synthetase, putative 0.0043 0.0122 0.2987
Echinococcus multilocularis rhodopsin orphan GPCR 0.0033 0.0089 0.046
Schistosoma mansoni ancient conserved domain protein 2 (cyclin m2) 0.0033 0.0089 0.0482
Trypanosoma cruzi dihydrolipoyl dehydrogenase, putative 0.0023 0.0056 0.1221
Schistosoma mansoni steroid hormone receptor ad4bp 0.0011 0.0013 0.0071
Plasmodium vivax multidrug resistance protein 1, putative 0.0012 0.0017 0.0174
Brugia malayi Cytochrome P450 family protein 0.0022 0.0051 0.0543
Mycobacterium leprae putative cytochrome p450 0.0022 0.0051 0.0051
Schistosoma mansoni cyclic nucleotide-gated ion channel 0.001 0.0011 0.0057
Mycobacterium tuberculosis Probable cytochrome P450 138 Cyp138 0.0022 0.0051 0.004
Echinococcus multilocularis ATP binding cassette subfamily B (MDR:TAP) 0.0012 0.0017 0.0067
Echinococcus granulosus leucyl tRNA synthetase 0.0043 0.0122 0.0664
Plasmodium vivax glutathione reductase, putative 0.0068 0.0207 0.5631
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0023 0.0056 0.1221
Echinococcus multilocularis hepatocyte nuclear factor 4 alpha 0.0011 0.0013 0.0048
Echinococcus granulosus hepatocyte nuclear factor 4 alpha 0.0011 0.0013 0.0071
Echinococcus granulosus follistatin 0.0081 0.0255 0.1385
Onchocerca volvulus 0.0033 0.0089 0.209
Brugia malayi Thioredoxin reductase 0.0068 0.0207 0.2223
Echinococcus granulosus Ankyrin 0.0015 0.0026 0.0141
Loa Loa (eye worm) unidentified vitellogenin-linked transcript protein 6 0.0033 0.0089 0.0677
Echinococcus multilocularis neuropeptide receptor 0.0033 0.0089 0.046
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0011 0.0013 0.014
Loa Loa (eye worm) steroid hormone receptor 0.0011 0.0013 0.0022
Brugia malayi beta-lactamase family protein 0.0075 0.0233 0.2494
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0033 0.0089 0.046
Schistosoma mansoni camp-dependent rap1 guanine-nucleotide exchange factor 0.001 0.0011 0.0057
Brugia malayi glutathione reductase 0.0068 0.0207 0.2223
Mycobacterium ulcerans cytochrome P450 143A3 Cyp143A3 0.0022 0.0051 0.004
Echinococcus multilocularis lamin dm0 0.0056 0.0168 0.0893
Mycobacterium ulcerans cytochrome P450 140A5 Cyp140A5 0.0022 0.0051 0.004
Trypanosoma brucei importin beta-1 subunit, putative 0.0032 0.0087 0.2382
Plasmodium falciparum glutathione reductase 0.0068 0.0207 0.5631
Trichomonas vaginalis voltage and ligand gated potassium channel, putative 0.001 0.0011 0.0292
Trichomonas vaginalis D-aminoacylase, putative 0.0075 0.0233 0.6462
Brugia malayi Dopamine receptor 0.0033 0.0089 0.0949
Echinococcus multilocularis transcription factor btf3 0.0112 0.036 0.194
Echinococcus multilocularis neuropeptide Y receptor 0.0033 0.0089 0.046
Leishmania major cytochrome p450-like protein 0.0022 0.0051 0.1149
Mycobacterium ulcerans cysteinyl-tRNA synthetase 0.0043 0.0122 0.0112
Echinococcus multilocularis neuropeptide receptor 0.0033 0.0089 0.046
Echinococcus granulosus nuclear factor of activated T cells 5 0.0074 0.023 0.1253
Schistosoma mansoni coup transcription factor 0.0011 0.0013 0.0071
Loa Loa (eye worm) hypothetical protein 0.0033 0.0089 0.0677
Brugia malayi sodium-independent organic anion transporter family protein 0.0119 0.0384 0.4115
Mycobacterium tuberculosis Dihydrolipoamide dehydrogenase LpdC (lipoamide reductase (NADH)) (lipoyl dehydrogenase) (dihydrolipoyl dehydrogenase) (diaphoras 0.0023 0.0056 0.0046
Loa Loa (eye worm) hypothetical protein 0.0011 0.0013 0.0022
Trichomonas vaginalis ABC transporter, putative 0.0012 0.0017 0.0461
Plasmodium falciparum dihydrolipoyl dehydrogenase, mitochondrial 0.0023 0.0056 0.1304
Brugia malayi Serotonin/octopamine receptor family protein 7 0.0033 0.0089 0.0949
Schistosoma mansoni retinoid-x-receptor (RXR) 0.0011 0.0013 0.0071
Echinococcus multilocularis pyroglutamylated rfamide peptide receptor 0.0033 0.0089 0.046
Onchocerca volvulus 0.0075 0.0233 0.5949
Echinococcus multilocularis beta LACTamase domain containing family member 0.0075 0.0233 0.1246
Loa Loa (eye worm) beta-LACTamase domain containing family member 0.0075 0.0233 0.1927
Loa Loa (eye worm) hypothetical protein 0.0033 0.0089 0.0677
Echinococcus multilocularis voltage gated potassium channel 0.0022 0.0052 0.0259
Leishmania major ubiquitin hydrolase, putative,cysteine peptidase, Clan CA, family C19, putative 0.0073 0.0228 0.6206
Echinococcus multilocularis cGMP dependent protein kinase 1 0.0011 0.0012 0.0044
Trichomonas vaginalis voltage and ligand gated potassium channel, putative 0.0071 0.0221 0.6128
Schistosoma mansoni ankyrin 23/unc44 0.0014 0.0026 0.0139
Echinococcus granulosus cAMP dependent protein kinase regulatory 0.001 0.0011 0.0057
Schistosoma mansoni neuropeptide receptor 0.0033 0.0089 0.0482
Brugia malayi neuropeptide F receptor 0.0033 0.0089 0.0949
Loa Loa (eye worm) hypothetical protein 0.0033 0.0089 0.0677
Trypanosoma cruzi mitogen-activated protein kinase 11, putative 0.0057 0.0173 0.4336
Brugia malayi Uncoordinated protein 44 0.0014 0.0026 0.0274
Brugia malayi hypothetical protein 0.0033 0.0089 0.0949
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0023 0.0056 0.1221
Echinococcus multilocularis hyperpolarization activated cyclic 0.0015 0.0028 0.0128
Mycobacterium ulcerans esterase/lipase LipP 0.0075 0.0233 0.0222
Trichomonas vaginalis ATP-binding cassette transporter, putative 0.0012 0.0017 0.0461
Schistosoma mansoni peptide (FMRFamide/neurokinin-3)-like receptor 0.0033 0.0089 0.0482
Echinococcus granulosus neuropeptides capa receptor 0.0033 0.0089 0.0482
Echinococcus granulosus multidrug resistance protein 1 0.0012 0.0017 0.009
Toxoplasma gondii HEAT repeat-containing protein 0.0032 0.0087 0.2052
Echinococcus multilocularis cAMP dependent protein kinase type II regulatory 0.001 0.0011 0.0034
Brugia malayi hypothetical protein 0.0033 0.0089 0.0949
Echinococcus granulosus growth hormone secretagogue receptor type 1 0.0033 0.0089 0.0482
Trypanosoma cruzi transcription factor btf3, putative 0.0112 0.036 0.9361
Onchocerca volvulus 0.0033 0.0089 0.209
Trichomonas vaginalis conserved hypothetical protein 0.0112 0.036 1
Trypanosoma cruzi cysteinyl-tRNA synthetase, putative 0.0043 0.0122 0.2987
Onchocerca volvulus 0.0081 0.0255 0.6534
Echinococcus granulosus organic anion transporting polypeptide 30B 0.0119 0.0384 0.2089
Echinococcus granulosus G protein coupled 5 hydroxytryptamine receptor 0.0033 0.0089 0.0482
Loa Loa (eye worm) hypothetical protein 0.0119 0.0384 0.324
Schistosoma mansoni cyclic-nucleotide-gated cation channel 0.0015 0.0028 0.0151
Echinococcus granulosus cysteinyl tRNA synthetase 0.0043 0.0122 0.0664
Schistosoma mansoni 60S ribosomal protein L21 0.0012 0.0017 0.0094
Loa Loa (eye worm) hypothetical protein 0.0119 0.0384 0.324
Loa Loa (eye worm) hypothetical protein 0.0033 0.0089 0.0677
Brugia malayi Steroid receptor seven-up type 2 0.0011 0.0013 0.014
Trichomonas vaginalis multidrug resistance protein 1, 2, putative 0.0012 0.0017 0.0461
Brugia malayi Cytochrome P450 family protein 0.0022 0.0051 0.0543
Echinococcus granulosus biogenic amine 5HT receptor 0.0033 0.0089 0.0482
Schistosoma mansoni voltage-gated potassium channel 0.0022 0.0052 0.0282
Echinococcus multilocularis netrin receptor unc 5 0.0014 0.0026 0.0116
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0075 0.0233 0.1266
Echinococcus granulosus cGMP dependent protein kinase 1 0.0011 0.0012 0.0067
Echinococcus granulosus cytochrome P450 2K1 0.0022 0.0051 0.0276
Echinococcus granulosus rhodopsin orphan GPCR 0.0033 0.0089 0.0482
Echinococcus multilocularis orexin receptor type 2 0.0033 0.0089 0.046
Echinococcus multilocularis potassium voltage gated channel subfamily H 0.0022 0.0052 0.0259
Schistosoma mansoni ran 0.0024 0.0058 0.0314
Brugia malayi photoreceptor-specific nuclear receptor 0.0011 0.0013 0.014
Brugia malayi G protein-coupled receptor 0.0033 0.0089 0.0949
Echinococcus multilocularis cysteinyl tRNA synthetase 0.0043 0.0122 0.0642
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0033 0.0089 0.046
Chlamydia trachomatis ABC transporter ATP binding protein/permease 0.0012 0.0017 0.0544
Trypanosoma cruzi mitogen-activated protein kinase 11, putative 0.0057 0.0173 0.4336
Loa Loa (eye worm) G-protein coupled receptor 0.0033 0.0089 0.0677
Echinococcus granulosus cAMP dependent protein kinase type I beta 0.001 0.0011 0.0057
Loa Loa (eye worm) CYP4Cod1 0.0076 0.0236 0.1955
Loa Loa (eye worm) hypothetical protein 0.0066 0.0203 0.1673
Echinococcus multilocularis ATP binding cassette sub family B 0.0012 0.0016 0.0065
Trypanosoma brucei GTP-binding nuclear protein rtb2, putative 0.0024 0.0058 0.1563
Schistosoma mansoni hypothetical protein 0.0014 0.0026 0.0139
Plasmodium falciparum basic transcription factor 3b, putative 0.0112 0.036 1
Toxoplasma gondii transporter, major facilitator family protein 0.0119 0.0384 1
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0033 0.0089 0.0482
Loa Loa (eye worm) hypothetical protein 0.0081 0.0255 0.2117
Schistosoma mansoni ubiquitin-specific peptidase 2 (C19 family) 0.0073 0.0228 0.1238
Onchocerca volvulus 0.0043 0.0122 0.2987
Entamoeba histolytica hypothetical protein 0.0112 0.036 1

Activities

Activity type Activity value Assay description Source Reference
Diet (functional) < 68 % In vivo triglyceride lowering activity dosed at 0.10 % of the diet. ChEMBL. 6604817
Diet (functional) = 92 % In vivo sterol lowering activity at dose of 0.10 % of the diet ChEMBL. 6604817
Inhibition (binding) < 68 % In vitro inhibition of acyl coenzyme A:cholesterol acyltransferase ChEMBL. 6604817
Inhibition (binding) < 68 % In vitro inhibition of acyl coenzyme A:cholesterol acyltransferase ChEMBL. 6604817

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
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External resources for this compound

Bibliographic References

1 literature reference was collected for this gene.

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