Species | Target name | Source | Bibliographic reference |
---|---|---|---|
Homo sapiens | egl-9 family hypoxia-inducible factor 1 | Starlite/ChEMBL | References |
Species | Potential target | Known druggable target/s | Ortholog Group |
---|---|---|---|
Loa Loa (eye worm) | hypothetical protein | Get druggable targets OG5_131326 | All targets in OG5_131326 |
Neospora caninum | 2OG-Fe(II) oxygenase family protein, putative | Get druggable targets OG5_131326 | All targets in OG5_131326 |
Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Loa Loa (eye worm) | hypothetical protein | 0.031 | 0.003 | 0.0033 |
Echinococcus multilocularis | COUP TF:Svp nuclear hormone receptor | 0.031 | 0.003 | 0.5 |
Echinococcus multilocularis | nuclear receptor 2DBD gamma | 0.031 | 0.003 | 0.5 |
Echinococcus granulosus | retinoic acid receptor rxr beta a | 0.031 | 0.003 | 0.5 |
Echinococcus multilocularis | nuclear receptor 2DBD gamma | 0.031 | 0.003 | 0.5 |
Loa Loa (eye worm) | nuclear Hormone Receptor family member | 0.031 | 0.003 | 0.0033 |
Loa Loa (eye worm) | hypothetical protein | 0.1717 | 0.9106 | 1 |
Echinococcus multilocularis | hepatocyte nuclear factor 4 alpha | 0.031 | 0.003 | 0.5 |
Loa Loa (eye worm) | hypothetical protein | 0.031 | 0.003 | 0.0033 |
Echinococcus multilocularis | ecdysone induced protein 78C | 0.031 | 0.003 | 0.5 |
Loa Loa (eye worm) | hypothetical protein | 0.031 | 0.003 | 0.0033 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-31 | 0.031 | 0.003 | 0.0033 |
Loa Loa (eye worm) | hypothetical protein | 0.031 | 0.003 | 0.0033 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-40 | 0.031 | 0.003 | 0.0033 |
Loa Loa (eye worm) | hypothetical protein | 0.031 | 0.003 | 0.0033 |
Loa Loa (eye worm) | hypothetical protein | 0.031 | 0.003 | 0.0033 |
Echinococcus granulosus | nuclear receptor 2DBD gamma | 0.031 | 0.003 | 0.5 |
Onchocerca volvulus | Bile acid receptor homolog | 0.1717 | 0.9106 | 1 |
Echinococcus multilocularis | FTZ F1 nuclear receptor protein | 0.031 | 0.003 | 0.5 |
Loa Loa (eye worm) | steroid hormone receptor | 0.031 | 0.003 | 0.0033 |
Echinococcus granulosus | ecdysone induced protein 78C | 0.031 | 0.003 | 0.5 |
Echinococcus granulosus | hepatocyte nuclear factor 4 alpha | 0.031 | 0.003 | 0.5 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-41 | 0.031 | 0.003 | 0.0033 |
Echinococcus granulosus | FTZ F1 nuclear receptor protein | 0.031 | 0.003 | 0.5 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-14 | 0.031 | 0.003 | 0.0033 |
Echinococcus granulosus | FTZ F1 alpha | 0.031 | 0.003 | 0.5 |
Echinococcus multilocularis | Nuclear hormone receptor family member nhr 41 | 0.031 | 0.003 | 0.5 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-1 | 0.031 | 0.003 | 0.0033 |
Loa Loa (eye worm) | hypothetical protein | 0.031 | 0.003 | 0.0033 |
Echinococcus multilocularis | FTZ F1 alpha | 0.031 | 0.003 | 0.5 |
Echinococcus granulosus | Nuclear hormone receptor family member nhr 41 | 0.031 | 0.003 | 0.5 |
Brugia malayi | ecdysteroid receptor | 0.1717 | 0.9106 | 1 |
Echinococcus multilocularis | thyroid hormone receptor alpha | 0.031 | 0.003 | 0.5 |
Echinococcus granulosus | nuclear receptor 2DBD gamma | 0.031 | 0.003 | 0.5 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-49 | 0.031 | 0.003 | 0.0033 |
Echinococcus granulosus | COUP TF:Svp nuclear hormone receptor | 0.031 | 0.003 | 0.5 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.
1 literature reference was collected for this gene.