Detailed information for compound 414728

Basic information

Technical information
  • Name: Unnamed compound
  • MW: 462.879 | Formula: C21H16ClFN2O5S
  • H donors: 2 H acceptors: 5 LogP: 4.27 Rotable bonds: 7
    Rule of 5 violations (Lipinski): 1
  • SMILES: Clc1ccc(cc1)N(S(=O)(=O)c1ccc(cc1)C(=O)Nc1ccc(cc1C(=O)O)F)C
  • InChi: 1S/C21H16ClFN2O5S/c1-25(16-7-4-14(22)5-8-16)31(29,30)17-9-2-13(3-10-17)20(26)24-19-11-6-15(23)12-18(19)21(27)28/h2-12H,1H3,(H,24,26)(H,27,28)
  • InChiKey: MBHYUJHFTKNTLU-UHFFFAOYSA-N  


Substructure search Similarity search

Network

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Synonyms

No synonyms found for this compound

Targets

Known targets for this compound

No curated genes were found associated with this compound

Predicted pathogen targets for this compound

By orthology
No druggable targets predicted by orthology data
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Mycobacterium leprae Probable lipase LipE 0.0167 0.0631 0.219
Schistosoma mansoni aldehyde dehydrogenase 0.0267 0.1043 0.1042
Schistosoma mansoni adenoreceptor 0.0033 0.0074 0.0073
Giardia lamblia Ubiquitin carboxyl-terminal hydrolase 4 0.0101 0.0355 0.0588
Echinococcus multilocularis histone lysine methyltransferase setb histone lysine methyltransferase eggless 0.0074 0.0241 0.024
Echinococcus multilocularis muscleblind protein 0.0427 0.1706 0.1705
Echinococcus granulosus COUP TF:Svp nuclear hormone receptor 0.003 0.006 0.0059
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0335 0.1326 0.1325
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0335 0.1326 0.1325
Loa Loa (eye worm) nuclear hormone receptor family member nhr-49 0.003 0.006 0.0101
Echinococcus granulosus bromodomain adjacent to zinc finger domain 0.0028 0.0054 0.0053
Trichomonas vaginalis CAMK family protein kinase 0.0044 0.0117 0.0158
Brugia malayi CHE-14 protein 0.0033 0.0074 0.0186
Leishmania major pyruvate kinase 0.0068 0.0217 0.1617
Echinococcus multilocularis transportin 1 0.0025 0.004 0.0038
Loa Loa (eye worm) hypothetical protein 0.0033 0.0074 0.0125
Onchocerca volvulus 0.0102 0.0359 0.0788
Schistosoma mansoni histamine h1 receptor 0.0033 0.0074 0.0073
Mycobacterium ulcerans aldehyde dehydrogenase 0.0267 0.1043 0.3785
Echinococcus multilocularis orexin receptor type 2 0.0033 0.0074 0.0073
Toxoplasma gondii ImpB/MucB/SamB family protein 0.0089 0.0303 0.2728
Schistosoma mansoni bcl-2 homologous antagonist/killer (bak) 0.008 0.0267 0.0266
Brugia malayi chromobox protein homolog 3 0.0038 0.0092 0.0231
Brugia malayi G-protein coupled receptor 0.0033 0.0074 0.0186
Brugia malayi RNA recognition motif domain containing protein 0.0054 0.0158 0.0397
Loa Loa (eye worm) ImpB/MucB/SamB family protein 0.007 0.0226 0.0387
Giardia lamblia Kinase, PLK 0.0088 0.0302 0.0493
Schistosoma mansoni hypothetical protein 0.0055 0.0166 0.0165
Brugia malayi Nuclear hormone receptor family member nhr-14 0.003 0.006 0.015
Echinococcus multilocularis endonuclease exonuclease phosphatase 0.0409 0.1634 0.1633
Onchocerca volvulus Serine\/threonine kinase homolog 0.0088 0.0302 0.0643
Loa Loa (eye worm) hypothetical protein 0.0167 0.0631 0.1084
Loa Loa (eye worm) hypothetical protein 0.0047 0.0132 0.0225
Loa Loa (eye worm) nuclear hormone receptor family member nhr-41 0.003 0.006 0.0101
Echinococcus granulosus histone lysine methyltransferase setb 0.0074 0.0241 0.024
Echinococcus multilocularis mixed lineage leukemia protein mll 0.0029 0.0056 0.0054
Schistosoma mansoni myosin xvIII 0.0033 0.0074 0.0073
Brugia malayi sulfakinin receptor protein 0.0033 0.0074 0.0186
Trypanosoma brucei DNA polymerase kappa, putative 0.0048 0.0136 0.0931
Echinococcus granulosus Nuclear hormone receptor family member nhr 41 0.003 0.006 0.0059
Loa Loa (eye worm) hypothetical protein 0.0022 0.0026 0.0042
Echinococcus multilocularis fetal alzheimer antigen, falz 0.0024 0.0035 0.0034
Onchocerca volvulus 0.0033 0.0074 0.0064
Echinococcus multilocularis ATP dependent DNA helicase Q1 0.0024 0.0034 0.0033
Trichomonas vaginalis conserved hypothetical protein 0.0024 0.0037 0.0016
Trypanosoma cruzi DNA polymerase beta thumb, putative 0.0043 0.0114 0.0751
Loa Loa (eye worm) hypothetical protein 0.005 0.0142 0.0242
Trichomonas vaginalis chromobox protein, putative 0.004 0.0104 0.0135
Loa Loa (eye worm) hypothetical protein 0.0024 0.0034 0.0056
Onchocerca volvulus 0.0033 0.0074 0.0064
Loa Loa (eye worm) jmjC domain-containing protein 0.0023 0.0033 0.0054
Toxoplasma gondii HEAT repeat-containing protein 0.0133 0.0486 0.4519
Trichomonas vaginalis conserved hypothetical protein 0.0024 0.0037 0.0016
Onchocerca volvulus 0.0033 0.0074 0.0064
Loa Loa (eye worm) hypothetical protein 0.0033 0.0074 0.0125
Echinococcus granulosus excitatory amino acid transporter 2 0.0975 0.3981 0.3981
Leishmania major importin beta-1 subunit, putative 0.0107 0.0382 0.3015
Trichomonas vaginalis CAMK family protein kinase 0.0088 0.0302 0.0488
Echinococcus multilocularis fmrfamide receptor 0.0033 0.0074 0.0073
Echinococcus multilocularis pyruvate kinase 0.0053 0.0158 0.0156
Echinococcus granulosus growth hormone secretagogue receptor type 1 0.0033 0.0074 0.0073
Brugia malayi kap beta 3 protein 0.0025 0.004 0.01
Echinococcus multilocularis sodium:dicarboxylate symporter 0.0975 0.3981 0.3981
Mycobacterium ulcerans cytochrome P450 51B1 Cyp51B1 0.0027 0.0046 0.0077
Echinococcus multilocularis Alpha N acetylgalactosaminidase 0.0075 0.0246 0.0244
Brugia malayi ATP-dependent DNA helicase, RecQ family protein 0.0024 0.0034 0.0086
Echinococcus granulosus neuropeptide receptor A26 0.0813 0.331 0.3309
Echinococcus multilocularis rhodopsin orphan GPCR 0.0033 0.0074 0.0073
Echinococcus multilocularis pyruvate kinase 0.0068 0.0217 0.0215
Schistosoma mansoni opsin-like receptor 0.0033 0.0074 0.0073
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0101 0.0355 0.0584
Trypanosoma brucei ubiquitin carboxyl-terminal hydrolase, putative 0.0101 0.0355 0.2788
Schistosoma mansoni hypothetical protein 0.008 0.0267 0.0266
Loa Loa (eye worm) hypothetical protein 0.0023 0.0033 0.0054
Brugia malayi putative neuropeptide receptor 0.0033 0.0074 0.0186
Echinococcus multilocularis GPCR, family 2 0.0055 0.0166 0.0165
Mycobacterium tuberculosis Probable nitrite reductase [NAD(P)H] large subunit [FAD flavoprotein] NirB 0.0091 0.0314 0.0618
Echinococcus granulosus histone lysine N methyltransferase MLL3 0.0036 0.0083 0.0082
Chlamydia trachomatis glutamate symporter 0.0975 0.3981 1
Onchocerca volvulus 0.0141 0.0521 0.1201
Mycobacterium ulcerans exodeoxyribonuclease III protein XthA 0.0038 0.0093 0.0248
Loa Loa (eye worm) beta-lactamase 0.0167 0.0631 0.1084
Schistosoma mansoni neuropeptide F-like receptor 0.0033 0.0074 0.0073
Entamoeba histolytica recQ family helicase, putative 0.0026 0.0045 0.001
Echinococcus multilocularis histone acetyltransferase MYST2 0.0116 0.0417 0.0416
Echinococcus multilocularis zinc finger protein 0.0028 0.0052 0.0051
Echinococcus multilocularis Niemann Pick C1 protein 0.0111 0.0396 0.0395
Onchocerca volvulus 0.0033 0.0074 0.0064
Mycobacterium tuberculosis Probable C4-dicarboxylate-transport transmembrane protein DctA 0.0975 0.3981 0.9089
Brugia malayi hypothetical protein 0.0026 0.0045 0.0112
Trichomonas vaginalis cat eye syndrome critical region protein 2, cscr2, putative 0.0078 0.0261 0.0415
Brugia malayi GnHR receptor homolog 0.0033 0.0074 0.0186
Brugia malayi Nuclear hormone receptor family member nhr-31 0.003 0.006 0.015
Trypanosoma brucei unspecified product 0.007 0.0226 0.1694
Mycobacterium ulcerans cytochrome P450 124A1, Cyp124A1 0.0027 0.0046 0.0077
Echinococcus granulosus zinc finger protein 0.0028 0.0052 0.0051
Brugia malayi jmjC domain containing protein 0.0023 0.0033 0.0082
Schistosoma mansoni cpg binding protein 0.0108 0.0383 0.0382
Echinococcus granulosus Niemann Pick C1 protein 0.0078 0.0258 0.0257
Trichomonas vaginalis conserved hypothetical protein 0.0024 0.0037 0.0016
Toxoplasma gondii histone lysine methyltransferase SET1 0.0215 0.0827 0.7873
Schistosoma mansoni jumonji/arid domain-containing protein 0.0095 0.0331 0.033
Brugia malayi hypothetical protein 0.0033 0.0074 0.0186
Echinococcus multilocularis tar DNA binding protein 0.0054 0.0158 0.0157
Loa Loa (eye worm) follicle stimulating hormone receptor 0.0033 0.0074 0.0125
Onchocerca volvulus 0.0071 0.0231 0.0463
Toxoplasma gondii cytochrome p450 superfamily protein 0.0027 0.0046 0.0202
Echinococcus multilocularis neuropeptides capa receptor 0.0033 0.0074 0.0073
Schistosoma mansoni cpg binding protein 0.0116 0.0415 0.0414
Echinococcus multilocularis atpase aaa+ type core atpase aaa type core 0.1423 0.5842 0.5841
Loa Loa (eye worm) hypothetical protein 0.0033 0.0074 0.0125
Trypanosoma brucei DNA polymerase kappa, putative 0.007 0.0226 0.1694
Brugia malayi Hypothetical 52.5 kDa protein ZK945.1 in chromosome II, putative 0.0167 0.0631 0.1584
Plasmodium vivax hypothetical protein, conserved 0.0027 0.0049 0.0772
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0035 0.0083 0.0097
Echinococcus granulosus Transcription factor JmjC domain containing protein 0.0144 0.0533 0.0532
Brugia malayi Nuclear hormone receptor family member nhr-49 0.003 0.006 0.015
Echinococcus multilocularis aldehyde dehydrogenase, mitochondrial 0.0267 0.1043 0.1042
Echinococcus granulosus neuropeptide FF receptor 2 0.0033 0.0074 0.0073
Schistosoma mansoni thyroid hormone receptor 0.003 0.006 0.0059
Mycobacterium leprae PROBABLE NADH DEHYDROGENASE NDH 0.0091 0.0314 0.1004
Loa Loa (eye worm) hypothetical protein 0.0033 0.0074 0.0125
Onchocerca volvulus 0.0033 0.0074 0.0064
Trypanosoma brucei DNA polymerase kappa, putative 0.007 0.0226 0.1694
Schistosoma mansoni jumonji domain containing protein 0.0126 0.0457 0.0456
Loa Loa (eye worm) PHD-finger family protein 0.0016 0.0004 0.0004
Schistosoma mansoni neuropeptide receptor 0.0033 0.0074 0.0073
Echinococcus granulosus rhodopsin orphan GPCR 0.0033 0.0074 0.0073
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.003 0.006 0.0059
Echinococcus granulosus histone acetyltransferase MYST2 0.0116 0.0417 0.0416
Plasmodium falciparum transportin 0.0025 0.004 0.0819
Giardia lamblia Pyruvate kinase 0.0068 0.0217 0.0341
Trypanosoma cruzi JmjC domain, hydroxylase, putative 0.0023 0.0033 0.006
Toxoplasma gondii thioredoxin reductase 0.004 0.0102 0.0746
Mycobacterium tuberculosis Probable esterase/lipase LipP 0.0167 0.0631 0.135
Echinococcus multilocularis serine:threonine protein kinase PLK1 0.0088 0.0302 0.03
Echinococcus multilocularis chromodomain helicase DNA binding protein 4 0.0019 0.0013 0.0012
Echinococcus multilocularis g protein coupled receptor 0.0033 0.0074 0.0073
Trypanosoma brucei DNA polymerase kappa, putative 0.0048 0.0136 0.0931
Giardia lamblia DINP protein human, muc B family 0.007 0.0226 0.0357
Trypanosoma brucei mitochondrial DNA polymerase beta 0.0306 0.1206 1
Schistosoma mansoni retinoid-x-receptor (RXR) 0.003 0.006 0.0059
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0033 0.0074 0.0073
Brugia malayi serine/threonine-protein kinase plk-2 0.0088 0.0302 0.0758
Loa Loa (eye worm) hypothetical protein 0.0033 0.0074 0.0125
Schistosoma mansoni aldehyde dehydrogenase 0.0267 0.1043 0.1042
Loa Loa (eye worm) hypothetical protein 0.0023 0.0033 0.0054
Trichomonas vaginalis chromobox protein, putative 0.004 0.0104 0.0135
Plasmodium falciparum AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.0038 0.0093 0.1906
Brugia malayi G protein-coupled receptor F59B2.13 0.0033 0.0074 0.0186
Loa Loa (eye worm) 5-hydroxytryptamine 2C receptor 0.0033 0.0074 0.0125
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0035 0.0083 0.0097
Leishmania major DNA polymerase kappa, putative 0.007 0.0226 0.1694
Echinococcus multilocularis neuropeptide receptor A26 0.0813 0.331 0.3309
Echinococcus granulosus Niemann Pick C1 protein 0.0111 0.0396 0.0395
Loa Loa (eye worm) hypothetical protein 0.0167 0.0631 0.1084
Schistosoma mansoni hypothetical protein 0.1536 0.6312 0.6311
Echinococcus granulosus dnaJ subfamily B 0.1536 0.6312 0.6311
Echinococcus granulosus expressed conserved protein 0.0073 0.0239 0.0237
Loa Loa (eye worm) MBCTL1 0.0116 0.0417 0.0717
Echinococcus multilocularis chromobox protein 1 0.0067 0.0214 0.0213
Loa Loa (eye worm) jmjC domain-containing protein 0.0023 0.0033 0.0054
Schistosoma mansoni alpha-1 adrenergic receptor 0.0033 0.0074 0.0073
Mycobacterium leprae conserved hypothetical protein 0.0167 0.0631 0.219
Brugia malayi Latrophilin receptor protein 2 0.0055 0.0166 0.0417
Schistosoma mansoni ubiquitin-specific peptidase 8 (C19 family) 0.0101 0.0355 0.0354
Mycobacterium ulcerans cytochrome P450 140A5 Cyp140A5 0.0027 0.0046 0.0077
Trypanosoma cruzi ubiquitin carboxyl-terminal hydrolase, putative 0.0101 0.0355 0.2788
Echinococcus granulosus g protein coupled receptor 0.0033 0.0074 0.0073
Echinococcus granulosus rhodopsin orphan GPCR 0.0033 0.0074 0.0073
Echinococcus multilocularis JmjC domain containing protein 4 0.0023 0.0033 0.0031
Schistosoma mansoni patched 1 0.0033 0.0074 0.0073
Schistosoma mansoni DNA helicase recq1 0.0024 0.0034 0.0033
Loa Loa (eye worm) hypothetical protein 0.0137 0.0503 0.0865
Mycobacterium ulcerans cytochrome P450 126A3 Cyp126A3 0.0027 0.0046 0.0077
Plasmodium falciparum ADP-dependent DNA helicase RecQ 0.0034 0.0077 0.1594
Loa Loa (eye worm) hypothetical protein 0.0033 0.0074 0.0125
Trypanosoma cruzi hypothetical protein, conserved 0.0167 0.0631 0.5124
Mycobacterium tuberculosis Probable exodeoxyribonuclease III protein XthA (exonuclease III) (EXO III) (AP endonuclease VI) 0.0038 0.0093 0.0107
Schistosoma mansoni steroid hormone receptor ad4bp 0.003 0.006 0.0059
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0167 0.0631 0.0629
Echinococcus multilocularis survival motor neuron protein 1 0.022 0.0849 0.0848
Loa Loa (eye worm) hypothetical protein 0.0033 0.0074 0.0125
Echinococcus multilocularis neuropeptide Y receptor 0.0033 0.0074 0.0073
Trichomonas vaginalis D-aminoacylase, putative 0.0167 0.0631 0.1076
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0024 0.0036 0.0013
Loa Loa (eye worm) importin-beta domain-containing protein 0.0025 0.004 0.0066
Toxoplasma gondii hypothetical protein 0.0049 0.0141 0.1129
Schistosoma mansoni zinc finger protein 0.0028 0.0052 0.0051
Trypanosoma cruzi DNA polymerase kappa, putative 0.007 0.0226 0.1694
Brugia malayi nuclear receptor NHR-88 0.003 0.006 0.015
Loa Loa (eye worm) cytochrome P450 family protein 0.0107 0.038 0.0652
Trichomonas vaginalis CAMK family protein kinase 0.0088 0.0302 0.0488
Loa Loa (eye worm) hypothetical protein 0.0033 0.0074 0.0125
Trichomonas vaginalis conserved hypothetical protein 0.0024 0.0037 0.0016
Echinococcus multilocularis rhodopsin orphan GPCR 0.0033 0.0074 0.0073
Loa Loa (eye worm) hypothetical protein 0.0167 0.0631 0.1084
Brugia malayi glutaminase DH11.1 0.0282 0.1107 0.2782
Schistosoma mansoni thyroid hormone receptor 0.003 0.006 0.0059
Echinococcus multilocularis polycomb protein SCMH1 0.0102 0.0359 0.0357
Loa Loa (eye worm) nuclear hormone receptor family member nhr-31 0.003 0.006 0.0101
Echinococcus granulosus tm gpcr rhodopsin 0.0033 0.0074 0.0073
Trichomonas vaginalis CAMK family protein kinase 0.0088 0.0302 0.0488
Brugia malayi RNA, U transporter 1 0.0377 0.1499 0.3766
Loa Loa (eye worm) hypothetical protein 0.0033 0.0074 0.0125
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0033 0.0074 0.0073
Brugia malayi jmjC domain containing protein 0.0023 0.0033 0.0082
Trypanosoma brucei DNA polymerase kappa, putative 0.007 0.0226 0.1694
Schistosoma mansoni nuclear hormone receptor 0.003 0.006 0.0059
Trypanosoma brucei DNA polymerase kappa, putative 0.007 0.0226 0.1694
Echinococcus multilocularis pyruvate kinase 0.0068 0.0217 0.0215
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.1371 0.5624 1
Schistosoma mansoni sodium/dicarboxylate symporter-related 0.0432 0.1729 0.1728
Echinococcus multilocularis dna polymerase kappa 0.007 0.0226 0.0224
Leishmania major DNA polymerase eta, putative 0.0137 0.0503 0.4045
Echinococcus multilocularis tachykinin peptides receptor 99D 0.0033 0.0074 0.0073
Brugia malayi hypothetical protein 0.0033 0.0074 0.0186
Brugia malayi Melibiase family protein 0.005 0.0142 0.0358
Echinococcus granulosus ecdysone induced protein 78C 0.003 0.006 0.0059
Plasmodium vivax glutathione reductase, putative 0.004 0.0102 0.1612
Brugia malayi hypothetical protein 0.0016 0.0001 0.0003
Trichomonas vaginalis alpha-galactosidase/alpha-N-acetylgalactosaminidase, putative 0.005 0.0142 0.0204
Leishmania major pyruvate kinase 0.0068 0.0217 0.1617
Brugia malayi Thioredoxin reductase 0.004 0.0102 0.0255
Brugia malayi Calcitonin receptor-like protein seb-1 0.0175 0.0663 0.1665
Onchocerca volvulus 0.0033 0.0074 0.0064
Mycobacterium tuberculosis Probable reductase 0.0091 0.0314 0.0618
Loa Loa (eye worm) kap beta 3 protein 0.0025 0.004 0.0066
Mycobacterium ulcerans DNA polymerase IV 0.007 0.0226 0.0744
Echinococcus multilocularis excitatory amino acid transporter 3 0.0975 0.3981 0.3981
Loa Loa (eye worm) hypothetical protein 0.0046 0.0128 0.0218
Loa Loa (eye worm) hypothetical protein 0.0033 0.0074 0.0125
Onchocerca volvulus Pyruvate kinase homolog 0.0068 0.0217 0.0427
Echinococcus multilocularis neutral amino acid transporter excitatory amino acid transporter 0.0975 0.3981 0.3981
Loa Loa (eye worm) glutaminase 0.0282 0.1107 0.1906
Echinococcus granulosus G protein coupled receptor 139 0.0033 0.0074 0.0073
Brugia malayi putative neuropeptide receptor NPR1 0.0033 0.0074 0.0186
Echinococcus multilocularis Jumonji, AT rich interactive domain 1B 0.0031 0.0065 0.0063
Loa Loa (eye worm) hypothetical protein 0.0016 0.0002 0.0001
Brugia malayi neuropeptide F receptor 0.0033 0.0074 0.0186
Toxoplasma gondii pyruvate kinase PyKII 0.0035 0.008 0.0532
Echinococcus multilocularis Peptidase C19, ubiquitin carboxyl terminal hydrolase 2 0.0101 0.0355 0.0354
Echinococcus granulosus ATP dependent DNA helicase Q1 0.0024 0.0034 0.0033
Brugia malayi Nuclear hormone receptor-like 1 0.0016 0.0001 0.0003
Echinococcus granulosus G protein coupled 5 hydroxytryptamine receptor 0.0033 0.0074 0.0073
Onchocerca volvulus 0.003 0.006 0.0028
Trypanosoma brucei pyruvate kinase 1, putative 0.0068 0.0217 0.1617
Brugia malayi beta-lactamase family protein 0.0167 0.0631 0.1584
Echinococcus multilocularis histone lysine N methyltransferase SETMAR 0.006 0.0185 0.0184
Trypanosoma cruzi DNA polymerase kappa, putative 0.007 0.0226 0.1694
Mycobacterium tuberculosis Probable conserved lipoprotein 0.0167 0.0631 0.135
Echinococcus multilocularis allatostatin A receptor 0.0033 0.0074 0.0073
Brugia malayi G-protein coupled receptor 0.0033 0.0074 0.0186
Leishmania major mitochondrial DNA polymerase beta 0.0306 0.1206 1
Trichomonas vaginalis conserved hypothetical protein 0.0024 0.0037 0.0016
Brugia malayi mbt repeat family protein 0.0102 0.0359 0.0901
Trypanosoma cruzi DNA polymerase eta, putative 0.0089 0.0303 0.2351
Mycobacterium ulcerans DNA polymerase IV 0.007 0.0226 0.0744
Echinococcus granulosus survival motor neuron protein 1 0.022 0.0849 0.0848
Echinococcus granulosus ubiquitin specific protease 41 0.0101 0.0355 0.0354
Schistosoma mansoni biogenic amine receptor 0.0033 0.0074 0.0073
Plasmodium falciparum pyruvate kinase 0.0068 0.0217 0.4462
Loa Loa (eye worm) cytochrome P450 family protein 0.0049 0.0141 0.024
Echinococcus granulosus neuropeptide receptor 0.0033 0.0074 0.0073
Loa Loa (eye worm) TYRA-2 protein 0.0033 0.0074 0.0125
Plasmodium falciparum ataxin-2 like protein, putative 0.005 0.0142 0.2918
Brugia malayi TAR-binding protein 0.0054 0.0158 0.0397
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0335 0.1326 0.1325
Echinococcus multilocularis G protein coupled 5 hydroxytryptamine receptor 0.0033 0.0074 0.0073
Mycobacterium ulcerans cytochrome P450 188A3 Cyp188A3 0.0027 0.0046 0.0077
Echinococcus multilocularis G protein coupled receptor 139 0.0033 0.0074 0.0073
Entamoeba histolytica deoxycytidyl transferase, putative 0.007 0.0226 0.0333
Loa Loa (eye worm) GTP-binding regulatory protein Gs alpha-S chain 0.0335 0.1326 0.2283
Trypanosoma cruzi mitochondrial DNA polymerase beta, putative 0.0306 0.1206 1
Echinococcus multilocularis dna polymerase eta 0.0137 0.0503 0.0502
Schistosoma mansoni histamine-responsive GPCR (AAF21638) 0.0033 0.0074 0.0073
Echinococcus multilocularis 0.0027 0.0046 0.0045
Trypanosoma cruzi apurinic/apyrimidinic endonuclease 0.0038 0.0093 0.0566
Mycobacterium ulcerans esterase/lipase LipP 0.0167 0.0631 0.225
Brugia malayi Bromodomain containing protein 0.0035 0.0083 0.0208
Loa Loa (eye worm) MH2 domain-containing protein 0.0095 0.033 0.0567
Trichomonas vaginalis CAMK family protein kinase 0.0044 0.0117 0.0158
Schistosoma mansoni acetyl-CoA C-acetyltransferase 0.0024 0.0035 0.0034
Schistosoma mansoni ap endonuclease 0.0038 0.0093 0.0091
Toxoplasma gondii LsmAD domain-containing protein 0.005 0.0142 0.1139
Echinococcus multilocularis Bcl 2 ous antagonist:killer 0.008 0.0267 0.0266
Trypanosoma cruzi DNA polymerase kappa, putative 0.007 0.0226 0.1694
Schistosoma mansoni growth hormone secretagogue receptor 0.0033 0.0074 0.0073
Trypanosoma cruzi hypothetical protein, conserved 0.0167 0.0631 0.5124
Echinococcus granulosus pyruvate kinase 0.0068 0.0217 0.0215
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0074 0.0241 0.024
Schistosoma mansoni kinase 0.0045 0.0122 0.012
Echinococcus multilocularis pyruvate kinase 0.0035 0.008 0.0079
Loa Loa (eye worm) pyruvate kinase 0.0068 0.0217 0.0371
Onchocerca volvulus Bile acid receptor homolog 0.003 0.006 0.0028
Loa Loa (eye worm) hypothetical protein 0.0167 0.0631 0.1084
Mycobacterium tuberculosis Probable aldehyde dehydrogenase 0.0267 0.1043 0.2303
Loa Loa (eye worm) hypothetical protein 0.0141 0.0521 0.0895
Schistosoma mansoni cytochrome P450 0.0027 0.0046 0.0045
Mycobacterium ulcerans cytochrome P450 105Q4 Cyp105Q4 0.0027 0.0046 0.0077
Brugia malayi calcium-independent alpha-latrotoxin receptor 2, putative 0.0055 0.0166 0.0417
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.006 0.0185 0.0184
Echinococcus multilocularis Ataxin 2, N terminal,domain containing protein 0.0022 0.0028 0.0027
Schistosoma mansoni bromodomain containing protein 0.0063 0.0196 0.0195
Loa Loa (eye worm) cytochrome P450 family protein 0.0049 0.0141 0.024
Schistosoma mansoni hypothetical protein 0.0032 0.0069 0.0068
Echinococcus granulosus fetal alzheimer antigen falz 0.0024 0.0035 0.0034
Schistosoma mansoni tar DNA-binding protein 0.0054 0.0158 0.0157
Plasmodium vivax histone acetyltransferase GCN5, putative 0.0078 0.0261 0.413
Schistosoma mansoni neuropeptide F-like receptor 0.0033 0.0074 0.0073
Toxoplasma gondii histone lysine methyltransferase SET/SUV39 0.006 0.0185 0.1567
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.1371 0.5624 1
Echinococcus granulosus lysine specific demethylase 6a 0.0023 0.0033 0.0031
Entamoeba histolytica fructose-1,6-bisphosphate aldolase, putative 0.1371 0.5624 1
Schistosoma mansoni coup transcription factor 0.003 0.006 0.0059
Toxoplasma gondii ABC1 family protein 0.0167 0.0631 0.5945
Echinococcus granulosus excitatory amino acid transporter 3 0.0975 0.3981 0.3981
Brugia malayi steroid hormone receptor 0.003 0.006 0.015
Loa Loa (eye worm) hypothetical protein 0.0033 0.0074 0.0125
Schistosoma mansoni peptide (FMRFamide/somatostatin)-like receptor 0.0033 0.0074 0.0073
Echinococcus granulosus peregrin 0.0035 0.0083 0.0082
Plasmodium falciparum glutathione reductase 0.004 0.0102 0.2093
Plasmodium vivax DNA repair protein REV1, putative 0.0022 0.0026 0.0409
Trichomonas vaginalis penicillin-binding protein, putative 0.0167 0.0631 0.1076
Echinococcus granulosus Alpha N acetylgalactosaminidase 0.0075 0.0246 0.0244
Brugia malayi Nuclear hormone receptor family member nhr-19 0.003 0.006 0.015
Echinococcus granulosus retinoic acid receptor rxr beta a 0.003 0.006 0.0059
Schistosoma mansoni ancient conserved domain protein 2 (cyclin m2) 0.0033 0.0074 0.0073
Mycobacterium ulcerans cytochrome P450 125A7 Cyp125A7 0.0027 0.0046 0.0077
Schistosoma mansoni tar DNA-binding protein 0.0054 0.0158 0.0157
Schistosoma mansoni apoptosis regulator bax 0.008 0.0267 0.0266
Mycobacterium ulcerans beta-lactamase 0.0167 0.0631 0.225
Loa Loa (eye worm) hypothetical protein 0.0033 0.0074 0.0125
Schistosoma mansoni DNA helicase recq5 0.0024 0.0034 0.0033
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.003 0.006 0.0059
Brugia malayi Nuclear hormone receptor family member nhr-3 0.003 0.006 0.015
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0033 0.0074 0.0073
Trypanosoma brucei DNA polymerase kappa, putative 0.007 0.0226 0.1694
Echinococcus granulosus serotonin receptor 0.0033 0.0074 0.0073
Loa Loa (eye worm) hypothetical protein 0.0033 0.0074 0.0125
Echinococcus granulosus fmrfamide receptor 0.0033 0.0074 0.0073
Brugia malayi hypothetical protein 0.0033 0.0074 0.0186
Plasmodium falciparum JmjC domain-containing protein, putative 0.0023 0.0033 0.0676
Echinococcus granulosus pyroglutamylated rfamide peptide receptor 0.0033 0.0074 0.0073
Brugia malayi ORL1-like opioid receptor 0.0033 0.0074 0.0186
Brugia malayi Nuclear hormone receptor-like 1 0.0016 0.0001 0.0003
Schistosoma mansoni hypothetical protein 0.1415 0.5806 0.5805
Trichomonas vaginalis DNA helicase recq, putative 0.0037 0.0089 0.0108
Trichomonas vaginalis D-aminoacylase, putative 0.0167 0.0631 0.1076
Onchocerca volvulus 0.0033 0.0074 0.0064
Loa Loa (eye worm) hypothetical protein 0.0033 0.0074 0.0125
Loa Loa (eye worm) steroid hormone receptor 0.003 0.006 0.0101
Echinococcus granulosus g protein coupled receptor 0.0033 0.0074 0.0073
Loa Loa (eye worm) acetyltransferase 0.0262 0.1021 0.1757
Onchocerca volvulus 0.0045 0.0122 0.0187
Loa Loa (eye worm) hypothetical protein 0.0033 0.0074 0.0125
Schistosoma mansoni peptide (allatostatin/somatostatin)-like receptor 0.0033 0.0074 0.0073
Trypanosoma cruzi cytochrome P450, putative 0.0049 0.0141 0.0972
Brugia malayi G-protein-linked acetylcholine receptor protein 2, putative 0.0033 0.0074 0.0186
Echinococcus granulosus polycomb protein SCMH1 0.0102 0.0359 0.0357
Plasmodium falciparum phd finger protein, putative 0.0027 0.0049 0.1003
Mycobacterium tuberculosis Possible DNA-damage-inducible protein P DinP (DNA polymerase V) (pol IV 2) (DNA nucleotidyltransferase (DNA-directed)) 0.007 0.0226 0.0414
Trypanosoma brucei DNA polymerase IV, putative 0.007 0.0226 0.1694
Echinococcus granulosus bloom syndrome protein 0.0037 0.0089 0.0087
Echinococcus granulosus neutral amino acid transporter A 0.0975 0.3981 0.3981
Brugia malayi CXXC zinc finger family protein 0.0108 0.0383 0.0963
Echinococcus multilocularis GTP binding nuclear protein Ran 0.0081 0.0271 0.027
Onchocerca volvulus 0.0167 0.0631 0.148
Echinococcus granulosus tar DNA binding protein 0.0054 0.0158 0.0157
Loa Loa (eye worm) hypothetical protein 0.0033 0.0074 0.0125
Schistosoma mansoni hypothetical protein 0.0032 0.0069 0.0068
Echinococcus granulosus lysine specific demethylase 5A 0.0095 0.0331 0.033
Echinococcus granulosus tumor protein p63 0.0359 0.1427 0.1426
Schistosoma mansoni amine GPCR 0.0033 0.0074 0.0073
Brugia malayi hypothetical protein 0.0033 0.0074 0.0186
Loa Loa (eye worm) hypothetical protein 0.003 0.006 0.0101
Echinococcus granulosus alpha 1A adrenergic receptor 0.0033 0.0074 0.0073
Loa Loa (eye worm) RNA recognition domain-containing protein domain-containing protein 0.0054 0.0158 0.027
Echinococcus multilocularis suppression of tumorigenicity 18 protein 0.0116 0.0417 0.0416
Brugia malayi Dopamine receptor protein 2 0.0033 0.0074 0.0186
Echinococcus multilocularis alpha 1A adrenergic receptor 0.0033 0.0074 0.0073
Echinococcus granulosus jumonji domain containing 1A 0.0023 0.0033 0.0031
Trichomonas vaginalis conserved hypothetical protein 0.0024 0.0037 0.0016
Echinococcus multilocularis gcn5proteinral control of amino acid synthesis 0.0262 0.1021 0.102
Onchocerca volvulus Heterochromatin protein 1 homolog 0.004 0.0104 0.014
Brugia malayi exodeoxyribonuclease III family protein 0.0038 0.0093 0.0233
Trichomonas vaginalis conserved hypothetical protein 0.0033 0.0074 0.0082
Echinococcus multilocularis protein patched 0.0033 0.0074 0.0073
Trypanosoma brucei DNA polymerase kappa, putative 0.007 0.0226 0.1694
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.1371 0.5624 1
Mycobacterium leprae DIHYDROLIPOAMIDE DEHYDROGENASE LPD (LIPOAMIDE REDUCTASE (NADH)) (LIPOYL DEHYDROGENASE) (DIHYDROLIPOYL DEHYDROGENASE) (DIAPHORASE 0.0101 0.0356 0.1162
Brugia malayi Dopamine receptor protein 1, putative (partial) 0.0033 0.0074 0.0186
Mycobacterium tuberculosis Probable esterase LipL 0.0167 0.0631 0.135
Loa Loa (eye worm) hypothetical protein 0.0033 0.0074 0.0125
Echinococcus granulosus tachykinin peptides receptor 99D 0.0033 0.0074 0.0073
Echinococcus multilocularis jumonji domain containing protein 0.0038 0.0093 0.0092
Mycobacterium ulcerans cytochrome p450 150 cyp150 0.0027 0.0046 0.0077
Echinococcus multilocularis protein dispatched 1 0.0038 0.0094 0.0092
Brugia malayi Corticotropin releasing factor receptor 2 precursor, putative 0.0318 0.1257 0.3157
Trichomonas vaginalis chromobox protein, putative 0.0067 0.0214 0.0332
Echinococcus granulosus neuropeptides capa receptor 0.0033 0.0074 0.0073
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0035 0.0083 0.0097
Echinococcus multilocularis thyrotropin releasing hormone receptor 0.0033 0.0074 0.0073
Trypanosoma brucei DNA polymerase kappa, putative 0.007 0.0226 0.1694
Trypanosoma brucei importin beta-1 subunit, putative 0.0133 0.0486 0.3896
Schistosoma mansoni hypothetical protein 0.0045 0.0122 0.0121
Loa Loa (eye worm) hypothetical protein 0.0318 0.1257 0.2163
Schistosoma mansoni cellular tumor antigen P53 0.0053 0.0154 0.0153
Loa Loa (eye worm) hypothetical protein 0.0033 0.0074 0.0125
Schistosoma mansoni neuropeptide receptor 0.0033 0.0074 0.0073
Schistosoma mansoni ran 0.0081 0.0271 0.027
Echinococcus multilocularis rhodopsin orphan GPCR 0.0033 0.0074 0.0073
Entamoeba histolytica pyruvate kinase, putative 0.0047 0.0132 0.0165
Brugia malayi hypothetical protein 0.0016 0.0001 0.0003
Brugia malayi hypothetical protein 0.0033 0.0074 0.0186
Mycobacterium ulcerans cytochrome P450 191A3 Cyp191A3 0.0027 0.0046 0.0077
Mycobacterium ulcerans cytochrome P450 189A7 Cyp189A7 0.0027 0.0046 0.0077
Echinococcus granulosus ATP dependent DNA helicase Q5 0.0024 0.0034 0.0033
Plasmodium falciparum DNA repair protein REV1, putative 0.0022 0.0026 0.0531
Giardia lamblia GTP-binding nuclear protein RAN/TC4 0.0081 0.0271 0.0439
Leishmania major hypothetical protein, conserved 0.0167 0.0631 0.5124
Brugia malayi Muscleblind-like protein 0.0427 0.1706 0.4286
Echinococcus granulosus hypothetical protein 0.0033 0.0074 0.0073
Mycobacterium tuberculosis Possible penicillin-binding protein 0.107 0.4376 1
Trichomonas vaginalis conserved hypothetical protein 0.0101 0.0355 0.0584
Entamoeba histolytica Ran family GTPase 0.0081 0.0271 0.0415
Echinococcus multilocularis neuropeptide Y receptor 0.0033 0.0074 0.0073
Loa Loa (eye worm) TAR-binding protein 0.0054 0.0158 0.027
Schistosoma mansoni blooms syndrome DNA helicase 0.0025 0.0039 0.0037
Loa Loa (eye worm) hypothetical protein 0.0033 0.0074 0.0125
Onchocerca volvulus 0.0167 0.0631 0.148
Schistosoma mansoni tar DNA-binding protein 0.0054 0.0158 0.0157
Trypanosoma brucei DNA polymerase eta, putative 0.0137 0.0503 0.4045
Leishmania major cytochrome p450-like protein 0.0027 0.0046 0.0175
Echinococcus granulosus serine:threonine protein kinase PLK1 0.0088 0.0302 0.03
Loa Loa (eye worm) beta-LACTamase domain containing family member 0.0167 0.0631 0.1084
Echinococcus granulosus thyrotropin releasing hormone receptor 0.0033 0.0074 0.0073
Loa Loa (eye worm) excitatory amino acid transporter 0.0975 0.3981 0.6857
Echinococcus granulosus pyruvate kinase 0.0068 0.0217 0.0215
Onchocerca volvulus 0.0167 0.0631 0.148
Onchocerca volvulus 0.0033 0.0074 0.0064
Loa Loa (eye worm) hypothetical protein 0.0116 0.0417 0.0717
Loa Loa (eye worm) CYP4Cod1 0.0049 0.0141 0.024
Echinococcus granulosus pyruvate kinase 0.0035 0.008 0.0079
Echinococcus multilocularis expressed conserved protein 0.0073 0.0239 0.0237
Brugia malayi ecdysteroid receptor 0.003 0.006 0.015
Giardia lamblia PHD finger protein 15 0.0027 0.0049 0.0041
Loa Loa (eye worm) hypothetical protein 0.0061 0.019 0.0325
Trypanosoma cruzi ubiquitin carboxyl-terminal hydrolase, putative 0.0101 0.0355 0.2788
Schistosoma mansoni niemann-pick C1 (NPC1) 0.0079 0.0263 0.0262
Toxoplasma gondii exonuclease III APE 0.0038 0.0093 0.0657
Mycobacterium ulcerans cytochrome P450 144A4 Cyp144A4 0.0027 0.0046 0.0077
Echinococcus multilocularis chromobox protein 1 0.0067 0.0214 0.0213
Loa Loa (eye worm) hypothetical protein 0.0033 0.0074 0.0125
Brugia malayi hypothetical protein 0.0032 0.0069 0.0173
Brugia malayi Melatonin receptor type 1A 0.0033 0.0074 0.0186
Loa Loa (eye worm) hypothetical protein 0.0033 0.0074 0.0125
Loa Loa (eye worm) abnormal chemotaxis protein 14 0.0033 0.0074 0.0125
Trichomonas vaginalis DNA helicase recq, putative 0.0026 0.0045 0.003
Loa Loa (eye worm) hypothetical protein 0.012 0.0434 0.0746
Mycobacterium tuberculosis Probable lipase LipD 0.0167 0.0631 0.135
Schistosoma mansoni hypothetical protein 0.0055 0.0166 0.0165
Onchocerca volvulus Pyruvate kinase homolog 0.0068 0.0217 0.0427
Echinococcus granulosus cytochrome P450 2K1 0.0027 0.0046 0.0045
Brugia malayi Nuclear hormone receptor family member nhr-25 0.003 0.006 0.015
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0033 0.0074 0.0073
Loa Loa (eye worm) G-protein coupled receptor 0.0033 0.0074 0.0125
Echinococcus granulosus neuropeptide receptor 0.0033 0.0074 0.0073
Onchocerca volvulus Protein ultraspiracle homolog 0.003 0.006 0.0028
Loa Loa (eye worm) nuclear Hormone Receptor family member 0.003 0.006 0.0101
Echinococcus multilocularis neuropeptides capa receptor 0.0033 0.0074 0.0073
Leishmania major cytochrome p450-like protein 0.0027 0.0046 0.0175
Loa Loa (eye worm) pigment dispersing factor receptor c 0.0175 0.0663 0.114
Brugia malayi hypothetical protein 0.0033 0.0074 0.0186
Brugia malayi Niemann-Pick C1 protein precursor 0.0078 0.0258 0.0648
Echinococcus multilocularis histone lysine N methyltransferase MLL3 0.0029 0.0056 0.0054
Schistosoma mansoni RAR-like nuclear receptor 0.003 0.006 0.0059
Mycobacterium tuberculosis Dihydrolipoamide dehydrogenase LpdC (lipoamide reductase (NADH)) (lipoyl dehydrogenase) (dihydrolipoyl dehydrogenase) (diaphoras 0.0101 0.0356 0.0716
Trypanosoma cruzi mitochondrial DNA polymerase beta-PAK, putative 0.0043 0.0114 0.0751
Schistosoma mansoni hypothetical protein 0.0016 0.0004 0.0002
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0035 0.0083 0.0097
Brugia malayi PHD-finger family protein 0.0027 0.0049 0.0122
Brugia malayi Steroid receptor seven-up type 2 0.003 0.006 0.015
Trypanosoma cruzi PAB1-binding protein , putative 0.005 0.0142 0.0982
Leishmania major DNA polymerase eta, putative 0.0089 0.0303 0.2351
Echinococcus granulosus suppression of tumorigenicity 18 protein 0.0116 0.0417 0.0416
Brugia malayi jmjC domain containing protein 0.0023 0.0033 0.0082
Loa Loa (eye worm) RecQ helicase 0.0037 0.0089 0.0151
Schistosoma mansoni sex comb on midleg homolog 0.0102 0.0359 0.0357
Loa Loa (eye worm) hypothetical protein 0.012 0.0433 0.0743
Echinococcus multilocularis Excitatory amino acid transporter 0.0975 0.3981 0.3981
Echinococcus multilocularis serotonin receptor 0.0033 0.0074 0.0073
Trichomonas vaginalis DNA polymerase IV / kappa, putative 0.007 0.0226 0.0353
Mycobacterium tuberculosis Conserved hypothetical protein 0.0161 0.0605 0.129
Schistosoma mansoni microtubule-associated protein tau 0.2425 1 1
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0038 0.0093 0.0091
Plasmodium vivax SET domain protein, putative 0.006 0.0185 0.2937
Loa Loa (eye worm) hypothetical protein 0.003 0.0058 0.0098
Loa Loa (eye worm) hypothetical protein 0.0033 0.0074 0.0125
Echinococcus multilocularis PHD finger protein rhinoceros 0.0027 0.0049 0.0047
Trichomonas vaginalis chromobox protein, putative 0.0067 0.0214 0.0332
Trypanosoma brucei DNA polymerase IV, putative 0.007 0.0226 0.1694
Brugia malayi hypothetical protein 0.022 0.0849 0.2133
Schistosoma mansoni alpha-galactosidase/alpha-n-acetylgalactosaminidase 0.0075 0.0246 0.0244
Trichomonas vaginalis bromodomain-containing protein, putative 0.0078 0.0261 0.0415
Loa Loa (eye worm) hypothetical protein 0.0033 0.0074 0.0125
Plasmodium vivax AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.0038 0.0093 0.1468
Brugia malayi Excitatory amino acid transporter 0.0975 0.3981 1
Mycobacterium ulcerans cytochrome P450 143A4 Cyp143A4 0.0027 0.0046 0.0077
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0167 0.0631 0.0629
Echinococcus granulosus terminal deoxycytidyl transferase rev1 0.007 0.0226 0.0224
Echinococcus granulosus SAM and MBT domain containing protein 0.0102 0.0359 0.0357
Brugia malayi Bromodomain containing protein 0.0072 0.0234 0.0589
Brugia malayi acetyltransferase, GNAT family protein 0.0262 0.1021 0.2565
Brugia malayi Serotonin receptor 0.0033 0.0074 0.0186
Trypanosoma brucei trypanothione reductase 0.004 0.0102 0.0643
Echinococcus multilocularis Glycoside hydrolase, family 27 0.0075 0.0246 0.0244
Schistosoma mansoni phosphatidylserine receptor 0.0023 0.0033 0.0031
Schistosoma mansoni hypothetical protein 0.0033 0.0074 0.0073
Mycobacterium ulcerans cytochrome P450 143A3 Cyp143A3 0.0027 0.0046 0.0077
Leishmania major DNA polymerase kappa, putative,DNA polymerase IV, putative 0.007 0.0226 0.1694
Trypanosoma cruzi PAB1-binding protein , putative 0.005 0.0142 0.0982
Echinococcus multilocularis phd:f box containing protein 0.0023 0.0033 0.0031
Onchocerca volvulus 0.0033 0.0074 0.0064
Brugia malayi Bloom's syndrome protein homolog 0.0037 0.0089 0.0223
Echinococcus multilocularis diuretic hormone 44 receptor GPRdih2 0.0199 0.076 0.0759
Trichomonas vaginalis conserved hypothetical protein 0.0027 0.0046 0.0032
Giardia lamblia Histone acetyltransferase GCN5 0.007 0.0226 0.0358
Echinococcus multilocularis sterol regulatory element binding protein 0.0033 0.0074 0.0073
Echinococcus multilocularis muscleblind protein 1 0.0427 0.1706 0.1705
Echinococcus granulosus histone lysine N methyltransferase MLL3 0.0029 0.0056 0.0054
Schistosoma mansoni opsin-like receptor 0.0033 0.0074 0.0073
Onchocerca volvulus 0.0033 0.0074 0.0064
Echinococcus granulosus Jumonji AT rich interactive domain 1B 0.0031 0.0065 0.0063
Trypanosoma cruzi mitochondrial DNA polymerase beta-PAK, putative 0.0145 0.0537 0.4331
Trypanosoma cruzi cytochrome p450-like protein, putative 0.0027 0.0046 0.0175
Leishmania major cytochrome p450-like protein 0.0049 0.0141 0.0972
Echinococcus multilocularis neuropeptide receptor 0.0033 0.0074 0.0073
Loa Loa (eye worm) hypothetical protein 0.0033 0.0074 0.0125
Schistosoma mansoni hypothetical protein 0.0022 0.0028 0.0027
Echinococcus granulosus importin 5 0.0025 0.004 0.0038
Loa Loa (eye worm) bromodomain containing protein 0.002 0.002 0.0033
Leishmania major GTP-binding protein, putative 0.0081 0.0271 0.208
Trypanosoma brucei DNA polymerase kappa, putative 0.007 0.0226 0.1694
Loa Loa (eye worm) hypothetical protein 0.003 0.006 0.0101
Trypanosoma cruzi pyruvate kinase 2, putative 0.0068 0.0217 0.1617
Loa Loa (eye worm) hypothetical protein 0.0102 0.0359 0.0616
Echinococcus multilocularis g-protein coupled receptor 0.0033 0.0074 0.0073
Echinococcus granulosus thioredoxin glutathione reductase 0.0041 0.0104 0.0103
Trypanosoma brucei Lanosterol 14-alpha demethylase 0.0027 0.0046 0.0175
Brugia malayi Nuclear hormone receptor family member nhr-1 0.003 0.006 0.015
Schistosoma mansoni hypothetical protein 0.0557 0.2246 0.2245
Schistosoma mansoni alpha-galactosidase/alpha-n-acetylgalactosaminidase 0.005 0.0142 0.0141
Echinococcus granulosus sodium:dicarboxylate symporter 0.0975 0.3981 0.3981
Echinococcus granulosus g-protein coupled receptor 0.0033 0.0074 0.0073
Trypanosoma brucei DNA polymerase beta thumb, putative 0.0043 0.0114 0.0751
Schistosoma mansoni glutaminase 0.0282 0.1107 0.1106
Echinococcus granulosus g protein linked acetylcholine receptor gar 2a 0.0033 0.0074 0.0073
Schistosoma mansoni ran 0.0081 0.0271 0.027
Loa Loa (eye worm) hypothetical protein 0.0033 0.0074 0.0125
Echinococcus granulosus Excitatory amino acid transporter 0.0975 0.3981 0.3981
Echinococcus granulosus PHD finger protein rhinoceros 0.0027 0.0049 0.0047
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.1371 0.5624 1
Brugia malayi Cytochrome P450 family protein 0.0107 0.038 0.0954
Onchocerca volvulus Excitatory amino acid transporter homolog 0.0975 0.3981 1
Mycobacterium ulcerans cytochrome P450 136A2 Cyp136A2 0.0027 0.0046 0.0077
Trypanosoma cruzi polo-like protein kinase, putative 0.0088 0.0302 0.2337
Toxoplasma gondii histone lysine acetyltransferase GCN5-A 0.0078 0.0261 0.2307
Echinococcus multilocularis rhodopsin orphan GPCR 0.0033 0.0074 0.0073
Entamoeba histolytica ubiquitin carboxyl-terminal hydrolase domain containing protein 0.0101 0.0355 0.0564
Echinococcus granulosus 7tm_1 domain containing protein 0.0033 0.0074 0.0073
Onchocerca volvulus Rap guanine nucleotide exchange factor 1 homolog 0.018 0.0681 0.1607
Trypanosoma brucei pyruvate kinase 1 0.0068 0.0217 0.1617
Toxoplasma gondii GTP-binding nuclear protein ran/tc4 0.0081 0.0271 0.2413
Loa Loa (eye worm) hypothetical protein 0.0033 0.0074 0.0125
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0033 0.0074 0.0073
Brugia malayi beta-lactamase 0.0167 0.0631 0.1584
Echinococcus multilocularis pyruvate kinase 0.0035 0.008 0.0079
Leishmania major protein kinase, putative,polo-like protein kinase, putative 0.0088 0.0302 0.2337
Echinococcus granulosus pyruvate kinase 0.0035 0.008 0.0079
Trypanosoma cruzi Lanosterol 14-alpha demethylase 0.0027 0.0046 0.0175
Loa Loa (eye worm) hypothetical protein 0.0033 0.0074 0.0125
Loa Loa (eye worm) exodeoxyribonuclease III family protein 0.0038 0.0093 0.0157
Schistosoma mansoni pyruvate kinase 0.0068 0.0217 0.0215
Echinococcus multilocularis microtubule associated protein 2 0.2425 1 1
Schistosoma mansoni sodium/dicarboxylate symporter-related 0.0432 0.1729 0.1728
Leishmania major trypanothione reductase 0.004 0.0102 0.0643
Trypanosoma cruzi GTP-binding nuclear protein rtb2, putative 0.0081 0.0271 0.208
Brugia malayi Pyruvate kinase, alpha/beta domain containing protein 0.002 0.0021 0.0052
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0335 0.1326 0.1325
Loa Loa (eye worm) pyruvate kinase 0.0068 0.0217 0.0371
Echinococcus granulosus phd:f box containing protein 0.0023 0.0033 0.0031
Brugia malayi mbt repeat family protein 0.0102 0.0359 0.0901
Loa Loa (eye worm) hypothetical protein 0.003 0.006 0.0101
Toxoplasma gondii histone lysine acetyltransferase GCN5-B 0.0078 0.0261 0.2307
Trypanosoma brucei unspecified product 0.0048 0.0136 0.0931
Echinococcus multilocularis FTZ F1 alpha 0.003 0.006 0.0059
Trypanosoma cruzi importin beta-1 subunit, putative 0.0107 0.0382 0.3015
Mycobacterium ulcerans fructose-bisphosphate aldolase 0.067 0.2714 1
Echinococcus granulosus neutral amino acid transporter 0.0975 0.3981 0.3981
Onchocerca volvulus 0.003 0.0058 0.0024
Trichomonas vaginalis pyruvate kinase, putative 0.0068 0.0217 0.0337
Echinococcus granulosus importin subunit beta 1 0.0133 0.0486 0.0484
Echinococcus multilocularis SAM and MBT domain containing protein 0.0102 0.0359 0.0357
Schistosoma mansoni myelin transcription factor 1 myt1 0.0116 0.0417 0.0416
Trypanosoma brucei JmjC domain, hydroxylase, putative 0.0023 0.0033 0.006
Trypanosoma cruzi mitochondrial DNA polymerase beta, putative 0.0306 0.1206 1
Loa Loa (eye worm) transcription factor SMAD2 0.0095 0.033 0.0567
Mycobacterium ulcerans hypothetical protein 0.0161 0.0605 0.2154
Echinococcus multilocularis cpg binding protein 0.0116 0.0415 0.0414
Brugia malayi PHD-finger family protein 0.0017 0.0005 0.0011
Brugia malayi ImpB/MucB/SamB family protein 0.007 0.0226 0.0567
Onchocerca volvulus Steroid hormone receptor family member cnr14 homolog 0.003 0.006 0.0028
Loa Loa (eye worm) nuclear hormone receptor family member nhr-40 0.003 0.006 0.0101
Mycobacterium tuberculosis Probable pyruvate kinase PykA 0.0068 0.0217 0.0393
Echinococcus granulosus somatostatin receptor 0.0033 0.0074 0.0073
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0033 0.0074 0.0073
Echinococcus granulosus chromodomain helicase DNA binding protein 4 0.0019 0.0013 0.0012
Loa Loa (eye worm) hypothetical protein 0.0033 0.0074 0.0125
Schistosoma mansoni ubiquitously transcribed sex (X/Y) chromosome tetratricopeptide repeat protein-related 0.0023 0.0033 0.0031
Mycobacterium ulcerans cytochrome P450 123A3 Cyp123A3 0.0027 0.0046 0.0077
Schistosoma mansoni amine GPCR 0.0033 0.0074 0.0073
Echinococcus granulosus chromobox protein 1 0.0067 0.0214 0.0213
Loa Loa (eye worm) hypothetical protein 0.003 0.006 0.0101
Mycobacterium tuberculosis Conserved protein 0.0167 0.0631 0.135
Loa Loa (eye worm) CXXC zinc finger family protein 0.0108 0.0383 0.0658
Echinococcus granulosus mixed lineage leukemia protein mll 0.0029 0.0056 0.0054
Echinococcus granulosus transportin 1 0.0025 0.004 0.0038
Loa Loa (eye worm) hypothetical protein 0.0017 0.0005 0.0005
Brugia malayi Apoptosis regulator proteins, Bcl-2 family protein 0.008 0.0267 0.067
Loa Loa (eye worm) hypothetical protein 0.0033 0.0074 0.0125
Schistosoma mansoni retinoic acid receptor RXR 0.003 0.006 0.0059
Trichomonas vaginalis set domain proteins, putative 0.0461 0.1848 0.3251
Echinococcus multilocularis Basic leucine zipper (bZIP) transcription 0.0026 0.0045 0.0043
Toxoplasma gondii PHD-finger domain-containing protein 0.0027 0.0049 0.0225
Echinococcus granulosus muscleblind protein 0.0427 0.1706 0.1705
Loa Loa (eye worm) hypothetical protein 0.0033 0.0074 0.0125
Brugia malayi polk-prov protein 0.0022 0.0026 0.0065
Schistosoma mansoni gcn5proteinral control of amino-acid synthesis 5-like 2 gcnl2 0.0262 0.1021 0.102
Echinococcus granulosus 5'partial|histone lysine N methyltransferase SETDB2 0.0056 0.0167 0.0165
Plasmodium vivax pyruvate kinase, putative 0.0068 0.0217 0.3435
Schistosoma mansoni solute carrier family 1 (glial high affinity glutamate transporter 0.0975 0.3981 0.3981
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0033 0.0074 0.0073
Trypanosoma cruzi DNA polymerase eta, putative 0.0137 0.0503 0.4045
Brugia malayi Cytochrome P450 family protein 0.0049 0.0141 0.0353
Loa Loa (eye worm) hypothetical protein 0.0167 0.0631 0.1084
Toxoplasma gondii HEAT repeat-containing protein 0.0025 0.004 0.0138
Mycobacterium tuberculosis Conserved protein 0.0167 0.0631 0.135
Entamoeba histolytica Niemann-Pick C1 protein, putative 0.0078 0.0258 0.0391
Echinococcus multilocularis G-protein coupled receptor, putative 0.0033 0.0074 0.0073
Leishmania major lanosterol 14-alpha-demethylase, putative 0.0027 0.0046 0.0175
Loa Loa (eye worm) hypothetical protein 0.0078 0.0258 0.0442
Treponema pallidum glutamate/aspartate transporter 0.0432 0.1729 0.2958
Schistosoma mansoni amine GPCR 0.0033 0.0074 0.0073
Brugia malayi F/Y-rich N-terminus family protein 0.0045 0.0125 0.0313
Echinococcus granulosus g protein linked acetylcholine receptor gar 2a 0.0033 0.0074 0.0073
Trypanosoma cruzi JmjC domain, hydroxylase, putative 0.0023 0.0033 0.006
Schistosoma mansoni hypothetical protein 0.008 0.0267 0.0266
Echinococcus granulosus allatostatin A receptor 0.0033 0.0074 0.0073
Loa Loa (eye worm) nuclear hormone receptor family member nhr-1 0.003 0.006 0.0101
Loa Loa (eye worm) hypothetical protein 0.022 0.0849 0.1461
Schistosoma mansoni terminal deoxycytidyl transferase 0.007 0.0226 0.0224
Loa Loa (eye worm) hypothetical protein 0.0033 0.0074 0.0125
Trichomonas vaginalis importin beta-1, putative 0.0107 0.0382 0.0631
Loa Loa (eye worm) thioredoxin reductase 0.004 0.0102 0.0173
Mycobacterium tuberculosis Conserved protein 0.0167 0.0631 0.135
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0335 0.1326 0.1325
Schistosoma mansoni survival motor neuron protein 0.0045 0.0122 0.0121
Schistosoma mansoni tar DNA-binding protein 0.0054 0.0158 0.0157
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.1371 0.5624 1
Brugia malayi MH2 domain containing protein 0.0095 0.033 0.0829
Brugia malayi PHD-finger family protein 0.0032 0.007 0.0175
Echinococcus granulosus histone acetyltransferase KAT2B 0.0252 0.0983 0.0982
Schistosoma mansoni chromobox protein 0.0067 0.0214 0.0213
Toxoplasma gondii aldehyde dehydrogenase 0.0267 0.1043 1
Loa Loa (eye worm) hypothetical protein 0.0023 0.003 0.0049
Echinococcus granulosus aldehyde dehydrogenase mitochondrial 0.0267 0.1043 0.1042
Mycobacterium ulcerans fusion of enoyl-CoA hydratase, EchA21 and lipase, LipE 0.0167 0.0631 0.225
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.003 0.006 0.015
Trypanosoma cruzi DNA polymerase kappa, putative 0.007 0.0226 0.1694
Plasmodium vivax pyruvate kinase 2, putative 0.0035 0.008 0.1268
Echinococcus multilocularis rhodopsin orphan GPCR 0.0033 0.0074 0.0073
Brugia malayi hypothetical protein 0.005 0.0142 0.0356
Trypanosoma cruzi ATP-dependent DEAD/H DNA helicase recQ, putative 0.0026 0.0045 0.0166
Leishmania major mitochondrial DNA polymerase beta-PAK, putative 0.0145 0.0537 0.4331
Plasmodium vivax JmjC domain containing protein 0.0023 0.0033 0.052
Echinococcus multilocularis growth hormone secretagogue receptor type 1 0.0033 0.0074 0.0073
Trichomonas vaginalis conserved hypothetical protein 0.0038 0.0092 0.0114
Brugia malayi Dopamine receptor 0.0033 0.0074 0.0186
Echinococcus multilocularis neuropeptide receptor 0.0033 0.0074 0.0073
Trichomonas vaginalis pyruvate kinase, putative 0.0068 0.0217 0.0337
Loa Loa (eye worm) ATP-dependent DNA helicase 0.0024 0.0034 0.0056
Echinococcus granulosus nuclear receptor 2DBD gamma 0.003 0.006 0.0059
Loa Loa (eye worm) hypothetical protein 0.0074 0.0241 0.0413
Schistosoma mansoni hypothetical protein 0.008 0.0267 0.0266
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0035 0.0083 0.0097
Schistosoma mansoni importin-beta 2 0.0025 0.004 0.0038
Loa Loa (eye worm) melatonin receptor type 1A 0.0033 0.0074 0.0125
Trypanosoma brucei DNA polymerase kappa, putative 0.007 0.0226 0.1694
Onchocerca volvulus Neuropeptide F receptor homolog 0.0033 0.0074 0.0064
Trichomonas vaginalis conserved hypothetical protein 0.0024 0.0037 0.0016
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.1371 0.5624 1
Brugia malayi latrophilin 2 splice variant baaae 0.012 0.0433 0.1087
Echinococcus multilocularis peregrin 0.0035 0.0083 0.0082
Onchocerca volvulus 0.0033 0.0074 0.0064
Loa Loa (eye worm) hypothetical protein 0.003 0.006 0.0101
Echinococcus granulosus dna polymerase kappa 0.007 0.0226 0.0224
Loa Loa (eye worm) hypothetical protein 0.0033 0.0074 0.0125
Trypanosoma cruzi polo-like protein kinase, putative 0.0088 0.0302 0.2337
Brugia malayi Nuclear hormone receptor-like 1 0.003 0.006 0.015
Loa Loa (eye worm) nuclear hormone receptor family member nhr-14 0.003 0.006 0.0101
Echinococcus multilocularis hepatocyte nuclear factor 4 alpha 0.003 0.006 0.0059
Schistosoma mansoni histone-lysine n-methyltransferase suv9 0.0071 0.0231 0.023
Schistosoma mansoni alpha-galactosidase/alpha-n-acetylgalactosaminidase 0.0075 0.0246 0.0244
Giardia lamblia Sgs1 DNA helicase, putative 0.0024 0.0034 0.0015
Entamoeba histolytica acetyltransferase, GNAT family 0.007 0.0226 0.0334
Plasmodium vivax hypothetical protein, conserved 0.0167 0.0631 1
Echinococcus multilocularis neutral amino acid transporter A 0.0975 0.3981 0.3981
Mycobacterium tuberculosis Possible conserved lipoprotein LpqK 0.0167 0.0631 0.135
Onchocerca volvulus 0.0053 0.0154 0.0268
Brugia malayi Nuclear hormone receptor family member nhr-40 0.003 0.006 0.015
Brugia malayi Bromodomain containing protein 0.0037 0.0088 0.0221
Echinococcus multilocularis neutral amino acid transporter excitatory amino acid transporter 0.0432 0.1729 0.1728
Toxoplasma gondii ATP-dependent DNA helicase, RecQ family protein 0.0022 0.0027 0.0015
Brugia malayi glutathione reductase 0.004 0.0102 0.0255
Leishmania major aldehyde dehydrogenase, mitochondrial precursor 0.0267 0.1043 0.862
Onchocerca volvulus 0.0033 0.0074 0.0064
Loa Loa (eye worm) hypothetical protein 0.0033 0.0074 0.0125
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0033 0.0074 0.0073
Schistosoma mansoni neuropeptide receptor 0.0033 0.0074 0.0073
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0033 0.0074 0.0073
Schistosoma mansoni hypothetical protein 0.0027 0.0046 0.0045
Loa Loa (eye worm) hypothetical protein 0.0033 0.0074 0.0125
Echinococcus multilocularis lysine specific demethylase 6a 0.0023 0.0033 0.0031
Echinococcus multilocularis importin 5 0.0025 0.004 0.0038
Brugia malayi Ubiquitin carboxyl-terminal hydrolase family protein 0.0101 0.0355 0.0891
Schistosoma mansoni bromodomain-containing nuclear protein 1 brd1 0.0027 0.0049 0.0047
Trichomonas vaginalis glutaminase, putative 0.0282 0.1107 0.1929
Echinococcus multilocularis sex peptide receptor 0.0033 0.0074 0.0073
Echinococcus multilocularis neutral amino acid transporter A 0.0975 0.3981 0.3981
Trypanosoma cruzi trypanothione reductase, putative 0.004 0.0102 0.0643
Mycobacterium ulcerans pyruvate kinase 0.0068 0.0217 0.071
Onchocerca volvulus 0.0033 0.0074 0.0064
Loa Loa (eye worm) hypothetical protein 0.0027 0.0049 0.0082
Loa Loa (eye worm) hypothetical protein 0.0167 0.0631 0.1084
Loa Loa (eye worm) hypothetical protein 0.0033 0.0074 0.0125
Schistosoma mansoni tar DNA-binding protein 0.0054 0.0158 0.0157
Toxoplasma gondii histone lysine demethylase JMJC1/KDM5D/JARID1D 0.0023 0.0033 0.0069
Loa Loa (eye worm) hypothetical protein 0.0033 0.0074 0.0125
Echinococcus granulosus biogenic amine 5HT receptor 0.0033 0.0074 0.0073
Trichomonas vaginalis helicase, putative 0.0024 0.0037 0.0016
Mycobacterium ulcerans lipase LipD 0.0167 0.0631 0.225
Brugia malayi CHD4 protein 0.0019 0.0013 0.0033
Trichomonas vaginalis CAMK family protein kinase 0.0088 0.0302 0.0488
Echinococcus granulosus dro:myosuppressin receptor 0.0033 0.0074 0.0073
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0231 0.0894 0.0893
Loa Loa (eye worm) hypothetical protein 0.003 0.006 0.0101
Entamoeba histolytica hypothetical protein 0.0026 0.0045 0.0009
Echinococcus granulosus rhodopsin orphan GPCR 0.0033 0.0074 0.0073
Mycobacterium tuberculosis NAD(P)H quinone reductase LpdA 0.0101 0.0356 0.0716
Treponema pallidum fructose-bisphosphate aldolase 0.1371 0.5624 1
Brugia malayi jmjC domain containing protein 0.0144 0.0533 0.1338
Trypanosoma brucei Importin-beta N-terminal domain/HEAT-like repeat, putative 0.0025 0.004 0.0119
Echinococcus granulosus rhodopsin orphan GPCR 0.0033 0.0074 0.0073
Brugia malayi Pyruvate kinase, muscle isozyme 0.0068 0.0217 0.0544
Leishmania major hypothetical protein, conserved 0.0025 0.004 0.0119
Echinococcus multilocularis translational activator gcn1 0.0025 0.004 0.0038
Schistosoma mansoni biogenic amine receptor 0.0033 0.0074 0.0073
Echinococcus granulosus chromobox protein 1 0.0067 0.0214 0.0213
Mycobacterium tuberculosis Probable dehydrogenase 0.0091 0.0314 0.0618
Brugia malayi Unidentified vitellogenin-linked transcript protein 6, putative 0.0033 0.0074 0.0186
Echinococcus granulosus Excitatory amino acid transporter 0.0975 0.3981 0.3981
Brugia malayi hypothetical protein 0.0033 0.0074 0.0186
Echinococcus multilocularis sodium:dicarboxylate symporter 0.0432 0.1729 0.1728
Brugia malayi nuclear receptor RXR 0.0016 0.0001 0.0003
Trypanosoma brucei ATP-dependent DEAD/H DNA helicase recQ, putative 0.0026 0.0045 0.0166
Mycobacterium ulcerans cytochrome P450 150A6 Cyp150A6 0.0027 0.0046 0.0077
Entamoeba histolytica serine/threonine protein kinase, putative 0.0088 0.0302 0.0469
Brugia malayi Iron-sulfur cluster assembly accessory protein 0.0045 0.0122 0.0307
Echinococcus multilocularis rhodopsin orphan GPCR 0.0033 0.0074 0.0073
Echinococcus multilocularis 7TM GPCR, rhodopsin 0.0033 0.0074 0.0073
Brugia malayi Heterochromatin protein 1 0.0067 0.0214 0.0538
Brugia malayi Pre-SET motif family protein 0.0405 0.1617 0.4061
Loa Loa (eye worm) pyruvate kinase-PB 0.0047 0.0132 0.0225
Onchocerca volvulus 0.0033 0.0074 0.0064
Schistosoma mansoni peptide (FMRFamide/somatostatin)-like receptor 0.0033 0.0074 0.0073
Schistosoma mansoni hypothetical protein 0.0026 0.0045 0.0043
Mycobacterium ulcerans cytochrome P450 187A5 Cyp187A5 0.0027 0.0046 0.0077
Echinococcus granulosus rhodopsin orphan GPCR 0.0033 0.0074 0.0073
Schistosoma mansoni cpg binding protein 0.0116 0.0415 0.0414
Echinococcus multilocularis geminin 0.0557 0.2246 0.2245
Mycobacterium tuberculosis Conserved hypothetical protein 0.007 0.0226 0.0414
Brugia malayi RE15519p 0.0033 0.0074 0.0186
Brugia malayi jmjC domain containing protein 0.0023 0.0033 0.0082
Trypanosoma brucei DNA polymerase kappa, putative 0.0048 0.0136 0.0931
Plasmodium falciparum ataxin-2 like protein, putative 0.005 0.0142 0.2918
Loa Loa (eye worm) glutathione reductase 0.004 0.0102 0.0173
Brugia malayi ATP-dependent DNA helicase, RecQ family protein 0.0024 0.0034 0.0086
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0074 0.0241 0.024
Schistosoma mansoni protein phosphatase 2C 0.0023 0.0033 0.0031
Echinococcus granulosus Ataxin 2 N terminaldomain containing protein 0.0022 0.0028 0.0027
Onchocerca volvulus 0.0033 0.0074 0.0064
Echinococcus multilocularis ubiquitin carboxyl terminal hydrolase 8 0.0101 0.0355 0.0354
Echinococcus multilocularis cadherin EGF LAG seven pass G type receptor 0.0055 0.0166 0.0165
Mycobacterium ulcerans cytochrome P450 142A3 Cyp142A3 0.0027 0.0046 0.0077
Echinococcus granulosus beta LACTamase domain containing family member 0.0167 0.0631 0.0629
Echinococcus multilocularis g protein linked acetylcholine receptor gar 2a 0.0033 0.0074 0.0073
Echinococcus granulosus ubiquitin carboxyl terminal hydrolase 8 0.0101 0.0355 0.0354
Echinococcus multilocularis somatostatin receptor 0.0033 0.0074 0.0073
Echinococcus granulosus FTZ F1 alpha 0.003 0.006 0.0059
Schistosoma mansoni hypothetical protein 0.0032 0.0069 0.0068
Echinococcus granulosus FTZ F1 nuclear receptor protein 0.003 0.006 0.0059
Brugia malayi nuclear hormone receptor 0.003 0.006 0.015
Brugia malayi AKH receptor 0.0033 0.0074 0.0186
Schistosoma mansoni chromobox protein 0.0067 0.0214 0.0213
Echinococcus multilocularis jumonji domain containing 1A 0.0023 0.0033 0.0031
Loa Loa (eye worm) hypothetical protein 0.0033 0.0074 0.0125
Echinococcus granulosus neuropeptide Y receptor 0.0033 0.0074 0.0073
Mycobacterium tuberculosis Probable lipase LipE 0.0167 0.0631 0.135
Echinococcus multilocularis pyruvate kinase 0.0035 0.008 0.0079
Mycobacterium tuberculosis Probable oxidoreductase 0.0101 0.0356 0.0716
Echinococcus multilocularis ubiquitin specific protease 41 0.0101 0.0355 0.0354
Echinococcus granulosus biogenic amine 5HT receptor 0.0033 0.0074 0.0073
Trypanosoma brucei polo-like protein kinase 0.0088 0.0302 0.2337
Brugia malayi larval opioid receptor 0.0033 0.0074 0.0186
Loa Loa (eye worm) hypothetical protein 0.005 0.0142 0.0243
Schistosoma mansoni nuclear hormone receptor nor-1/nor-2 0.003 0.006 0.0059
Echinococcus granulosus rhodopsin orphan GPCR 0.0033 0.0074 0.0073
Echinococcus multilocularis dro:myosuppressin receptor 0.0033 0.0074 0.0073
Schistosoma mansoni serine/threonine protein kinase 0.0088 0.0302 0.03
Schistosoma mansoni scm-relatedprotein containing 4 mbt domains (sfmbt) 0.0102 0.0359 0.0357
Schistosoma mansoni thyrotropin-releasing hormone receptor 0.0033 0.0074 0.0073
Echinococcus multilocularis bloom syndrome protein 0.0037 0.0089 0.0087
Echinococcus granulosus GTP binding nuclear protein Ran 0.0081 0.0271 0.027
Brugia malayi Cytochrome P450 family protein 0.0027 0.0046 0.0117
Schistosoma mansoni nuclear receptor 2DBD-gamma 0.003 0.006 0.0059
Echinococcus multilocularis ATP dependent DNA helicase Q5 0.0024 0.0034 0.0033
Trypanosoma brucei hypothetical protein, conserved 0.0167 0.0631 0.5124
Echinococcus multilocularis neuropeptide FF receptor 2 0.0033 0.0074 0.0073
Echinococcus granulosus cpg binding protein 0.0116 0.0415 0.0414
Brugia malayi GTP-binding nuclear protein RAN/TC4 0.0081 0.0271 0.0681
Entamoeba histolytica exodeoxyribonuclease III, putative 0.0038 0.0093 0.0095
Brugia malayi jmjC domain containing protein 0.0095 0.0331 0.0833
Echinococcus granulosus nuclear receptor 2DBD gamma 0.003 0.006 0.0059
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0033 0.0074 0.0073
Echinococcus granulosus diuretic hormone 44 receptor GPRdih2 0.0199 0.076 0.0759
Echinococcus granulosus orexin receptor type 2 0.0033 0.0074 0.0073
Mycobacterium ulcerans hypothetical protein 0.0167 0.0631 0.225
Echinococcus multilocularis tumor protein p63 0.0359 0.1427 0.1426
Trichomonas vaginalis conserved hypothetical protein 0.0024 0.0037 0.0016
Loa Loa (eye worm) PLK/PLK1 protein kinase 0.0088 0.0302 0.0517
Schistosoma mansoni biogenic amine (octopamine/dopamine) receptor 0.0033 0.0074 0.0073
Loa Loa (eye worm) hypothetical protein 0.0039 0.0096 0.0163
Trypanosoma brucei cytochrome P450, putative 0.0049 0.0141 0.0972
Loa Loa (eye worm) hypothetical protein 0.0427 0.1706 0.2937
Schistosoma mansoni ap endonuclease 0.0038 0.0093 0.0091
Echinococcus granulosus histone acetyltransferase KAT2B 0.0078 0.0261 0.0259
Plasmodium falciparum GTP-binding nuclear protein RAN/TC4 0.0081 0.0271 0.5586
Echinococcus multilocularis g protein coupled receptor 0.0033 0.0074 0.0073
Onchocerca volvulus Dopamine\/Ecdysteroid receptor homolog 0.0033 0.0074 0.0064
Schistosoma mansoni biogenic amine (5HT) receptor 0.0033 0.0074 0.0073
Mycobacterium ulcerans cytochrome P450 185A4 Cyp185A4 0.0049 0.0141 0.0427
Echinococcus granulosus hepatocyte nuclear factor 4 alpha 0.003 0.006 0.0059
Schistosoma mansoni neuropeptide f receptor 76f 0.0033 0.0074 0.0073
Loa Loa (eye worm) G-protein-linked acetylcholine receptor protein 2 0.0033 0.0074 0.0125
Echinococcus granulosus snurportin 1 0.1415 0.5806 0.5805
Onchocerca volvulus Polycomb protein Sfmbt homolog 0.0102 0.0359 0.0788
Loa Loa (eye worm) jmjC domain-containing protein 0.0056 0.0169 0.0289
Trichomonas vaginalis ap endonuclease, putative 0.0038 0.0093 0.0115
Giardia lamblia Fructose-bisphosphate aldolase 0.1371 0.5624 1
Trichomonas vaginalis DNA polymerase eta, putative 0.007 0.0226 0.0353
Brugia malayi N-terminal motif family protein 0.018 0.0681 0.171
Echinococcus granulosus Protein patched homolog 1 0.0033 0.0074 0.0073
Echinococcus granulosus neuropeptide Y receptor 0.0033 0.0074 0.0073
Echinococcus multilocularis neutral amino acid transporter A 0.0975 0.3981 0.3981
Loa Loa (eye worm) GTP-binding nuclear protein RAN/TC4 0.0081 0.0271 0.0465
Plasmodium vivax ataxin-2 like protein, putative 0.005 0.0142 0.2247
Onchocerca volvulus 0.0033 0.0074 0.0064
Schistosoma mansoni biogenic amine (5HT) receptor 0.0033 0.0074 0.0073
Plasmodium vivax GTP-binding nuclear protein RAN/TC4, putative 0.0081 0.0271 0.4301
Schistosoma mansoni hypothetical protein 0.0032 0.0069 0.0068
Plasmodium vivax thioredoxin reductase, putative 0.004 0.0102 0.1612
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0335 0.1326 0.1325
Loa Loa (eye worm) hypothetical protein 0.0033 0.0074 0.0125
Loa Loa (eye worm) hypothetical protein 0.008 0.0267 0.0458
Brugia malayi Nuclear hormone receptor family member nhr-41 0.003 0.006 0.015
Echinococcus multilocularis bromodomain adjacent to zinc finger domain 0.006 0.0184 0.0183
Echinococcus multilocularis dnaJ subfamily B 0.1536 0.6312 0.6311
Schistosoma mansoni jumonji/arid domain-containing protein 0.0095 0.0331 0.033
Loa Loa (eye worm) hypothetical protein 0.0101 0.0355 0.0609
Schistosoma mansoni muscarinic acetylcholine (GAR) receptor 0.0033 0.0074 0.0073
Trypanosoma cruzi mitochondrial DNA polymerase beta-PAK, putative 0.0052 0.0154 0.1082
Schistosoma mansoni peptide (allatostatin)-like receptor 0.0033 0.0074 0.0073
Wolbachia endosymbiont of Brugia malayi Na+/H+-dicarboxylate symporter 0.0975 0.3981 1
Loa Loa (eye worm) pre-SET domain-containing protein family protein 0.0405 0.1617 0.2783
Loa Loa (eye worm) gonadotropin-releasing hormone receptor 2 0.0033 0.0074 0.0125
Echinococcus multilocularis EGFP:Bcl2 fusion protein 0.008 0.0267 0.0266
Brugia malayi hypothetical protein 0.0033 0.0074 0.0186
Echinococcus multilocularis neuropeptide s receptor 0.0813 0.331 0.3309
Echinococcus granulosus geminin 0.0557 0.2246 0.2245
Plasmodium vivax ADP-dependent DNA helicase RecQ, putative 0.0023 0.0029 0.0463
Schistosoma mansoni hypothetical protein 0.0033 0.0074 0.0073
Mycobacterium ulcerans glutaminase 0.0282 0.1107 0.4023
Loa Loa (eye worm) hypothetical protein 0.0055 0.0166 0.0283
Mycobacterium ulcerans cytochrome P450 108B4 Cyp108B4 0.0027 0.0046 0.0077
Loa Loa (eye worm) hypothetical protein 0.0038 0.0092 0.0156
Trichomonas vaginalis conserved hypothetical protein 0.0038 0.0092 0.0114
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.1371 0.5624 1
Brugia malayi Cytochrome P450 family protein 0.0049 0.0141 0.0353
Trypanosoma cruzi apurinic/apyrimidinic endonuclease, putative 0.0038 0.0093 0.0566
Loa Loa (eye worm) hypothetical protein 0.0033 0.0074 0.0125
Schistosoma mansoni photoreceptor-specific nuclear receptor related 0.003 0.006 0.0059
Echinococcus granulosus GPCR family 2 0.0055 0.0166 0.0165
Loa Loa (eye worm) nucleolar RNA-associated protein alpha 0.1415 0.5806 1
Brugia malayi ImpB/MucB/SamB family protein 0.0137 0.0503 0.1264
Plasmodium falciparum importin beta, putative 0.0133 0.0486 1
Schistosoma mansoni ubiquitin-specific peptidase 2 (C19 family) 0.0101 0.0355 0.0354
Loa Loa (eye worm) hypothetical protein 0.003 0.0062 0.0104
Loa Loa (eye worm) hypothetical protein 0.0068 0.0217 0.0371
Echinococcus granulosus jumonji domain containing protein 0.0038 0.0093 0.0092
Plasmodium vivax importin-beta 2, putative 0.0133 0.0486 0.77
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.003 0.006 0.015
Loa Loa (eye worm) hypothetical protein 0.003 0.006 0.0101
Echinococcus granulosus JmjC domain containing protein 4 0.0023 0.0033 0.0031
Schistosoma mansoni DNA polymerase eta 0.0137 0.0503 0.0502
Echinococcus multilocularis biogenic amine (5HT) receptor 0.0033 0.0074 0.0073
Echinococcus granulosus Bcl 2 ous antagonist:killer 0.008 0.0267 0.0266
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0033 0.0074 0.0073
Schistosoma mansoni hypothetical protein 0.0055 0.0166 0.0165
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0335 0.1326 0.1325
Loa Loa (eye worm) RNA binding protein 0.0054 0.0158 0.027
Echinococcus multilocularis Excitatory amino acid transporter 0.0975 0.3981 0.3981
Echinococcus granulosus bromodomain adjacent to zinc finger domain 0.006 0.0184 0.0183
Toxoplasma gondii histone lysine demethylase JMJD6a 0.0023 0.0033 0.0069
Schistosoma mansoni hypothetical protein 0.0557 0.2246 0.2245
Plasmodium falciparum pyruvate kinase 2 0.0035 0.008 0.1647
Echinococcus multilocularis Nuclear hormone receptor family member nhr 41 0.003 0.006 0.0059
Trypanosoma brucei GTP-binding nuclear protein rtb2, putative 0.0081 0.0271 0.208
Schistosoma mansoni Tr4/Tr2 (homologue) 0.003 0.006 0.0059
Echinococcus multilocularis bromodomain adjacent to zinc finger domain 0.0028 0.0054 0.0053
Brugia malayi Dopamine receptor protein 1 0.0033 0.0074 0.0186
Brugia malayi Importin beta-1 subunit 0.0133 0.0486 0.122
Loa Loa (eye worm) latrophilin receptor protein 2 0.0055 0.0166 0.0283
Entamoeba histolytica hypothetical protein 0.0107 0.0382 0.0612
Trypanosoma brucei DNA polymerase IV, putative 0.007 0.0226 0.1694
Trypanosoma cruzi GTP-binding nuclear protein rtb2, putative 0.0081 0.0271 0.208
Mycobacterium tuberculosis NADPH-dependent mycothiol reductase Mtr 0.004 0.0102 0.0128
Echinococcus granulosus Basic leucine zipper bZIP transcription 0.0026 0.0045 0.0043
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0035 0.0083 0.0097
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0033 0.0074 0.0073
Echinococcus multilocularis COUP TF:Svp nuclear hormone receptor 0.003 0.006 0.0059
Giardia lamblia Pyruvate kinase 0.0035 0.008 0.0097
Echinococcus multilocularis excitatory amino acid transporter 2 0.0975 0.3981 0.3981
Treponema pallidum glutamate transporter 0.0432 0.1729 0.2958
Onchocerca volvulus Heterochromatin protein 1 homolog 0.0038 0.0092 0.011
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0035 0.0083 0.0097
Loa Loa (eye worm) hypothetical protein 0.0427 0.1706 0.2937
Schistosoma mansoni amine GPCR 0.0033 0.0074 0.0073
Echinococcus multilocularis snurportin 1 0.1415 0.5806 0.5805
Mycobacterium leprae Probable fructose bisphosphate aldolase Fba 0.067 0.2714 1
Schistosoma mansoni peptide (FMRFamide/neurokinin-3)-like receptor 0.0033 0.0074 0.0073
Trichomonas vaginalis conserved hypothetical protein 0.0024 0.0037 0.0016
Echinococcus granulosus 7TM GPCR rhodopsin 0.0033 0.0074 0.0073
Mycobacterium tuberculosis Putative ferredoxin reductase 0.0091 0.0314 0.0618
Echinococcus multilocularis FTZ F1 nuclear receptor protein 0.003 0.006 0.0059
Schistosoma mansoni hypothetical protein 0.012 0.0433 0.0431
Loa Loa (eye worm) hypothetical protein 0.0033 0.0074 0.0125
Brugia malayi photoreceptor-specific nuclear receptor 0.003 0.006 0.015
Schistosoma mansoni alpha-galactosidase/alpha-n-acetylgalactosaminidase 0.0075 0.0246 0.0244
Schistosoma mansoni hypothetical protein 0.0027 0.0049 0.0047
Entamoeba histolytica fructose-1,6-bisphosphate aldolase, putative 0.1371 0.5624 1
Trichomonas vaginalis CAMK family protein kinase 0.0088 0.0302 0.0488
Trypanosoma brucei apurinic/apyrimidinic endonuclease, putative 0.0038 0.0093 0.0566
Echinococcus multilocularis DNA (apurinic or apyrimidinic site) lyase 0.0038 0.0093 0.0091
Entamoeba histolytica hypothetical protein 0.0026 0.0045 0.0009
Toxoplasma gondii pyruvate kinase PyK1 0.0068 0.0217 0.1876
Echinococcus multilocularis Niemann Pick C1 protein 0.0078 0.0258 0.0257
Mycobacterium ulcerans aldehyde dehydrogenase 0.0267 0.1043 0.3785
Loa Loa (eye worm) hypothetical protein 0.0056 0.0168 0.0288
Toxoplasma gondii ATP-dependent DNA helicase, RecQ family protein 0.0024 0.0034 0.0082
Brugia malayi cytochrome P450 0.0027 0.0046 0.0117
Trypanosoma cruzi Lanosterol 14-alpha demethylase 0.0027 0.0046 0.0175
Onchocerca volvulus 0.0461 0.1848 0.4574
Echinococcus multilocularis importin subunit beta 1 0.0133 0.0486 0.0484
Schistosoma mansoni hypothetical protein 0.0055 0.0166 0.0165
Leishmania major ubiquitin hydrolase, putative,cysteine peptidase, Clan CA, family C19, putative 0.0101 0.0355 0.2788
Brugia malayi follicle stimulating hormone receptor 0.0033 0.0074 0.0186
Echinococcus multilocularis ecdysone induced protein 78C 0.003 0.006 0.0059
Trichomonas vaginalis Importin beta-1 subunit, putative 0.0107 0.0382 0.0631
Echinococcus granulosus rhodopsin orphan GPCR 0.0033 0.0074 0.0073
Brugia malayi Tachykinin-like peptides receptor 99D 0.0033 0.0074 0.0186
Echinococcus granulosus neutral amino acid transporter A 0.0975 0.3981 0.3981
Loa Loa (eye worm) neuropeptide F receptor 0.0033 0.0074 0.0125
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.1371 0.5624 1
Trypanosoma brucei importin beta-1 subunit, putative 0.0133 0.0486 0.3896
Schistosoma mansoni hypothetical protein 0.0033 0.0074 0.0073
Brugia malayi Serotonin receptor 0.0033 0.0074 0.0186
Echinococcus multilocularis peptide (allatostatin:somatostatin) 0.0033 0.0074 0.0073
Schistosoma mansoni jumonji domain containing protein 0.0023 0.0033 0.0031
Brugia malayi Pyruvate kinase, M2 isozyme 0.0068 0.0217 0.0544
Schistosoma mansoni importin beta-1 0.0133 0.0486 0.0484
Echinococcus granulosus cadherin EGF LAG seven pass G type receptor 0.0055 0.0166 0.0165
Brugia malayi Pre-SET motif family protein 0.006 0.0185 0.0465
Echinococcus granulosus sterol regulatory element binding protein 0.0033 0.0074 0.0073
Loa Loa (eye worm) glutaminase 2 0.0282 0.1107 0.1906
Brugia malayi hypothetical protein 0.0033 0.0074 0.0186
Brugia malayi Serotonin/octopamine receptor family protein 7 0.0033 0.0074 0.0186
Echinococcus multilocularis g protein coupled receptor 0.0033 0.0074 0.0073
Leishmania major ATP-dependent DEAD/H DNA helicase recQ, putative 0.0026 0.0045 0.0166
Echinococcus granulosus peptide allatostatin:somatostatin 0.0033 0.0074 0.0073
Loa Loa (eye worm) hypothetical protein 0.0033 0.0074 0.0125
Schistosoma mansoni alpha-galactosidase/alpha-n-acetylgalactosaminidase 0.0075 0.0246 0.0244
Schistosoma mansoni pyruvate kinase 0.0035 0.008 0.0079
Trypanosoma cruzi DNA polymerase beta thumb, putative 0.0043 0.0114 0.0751
Trypanosoma cruzi pyruvate kinase 2, putative 0.0068 0.0217 0.1617
Chlamydia trachomatis neutral amino acid transporter 0.0432 0.1729 0.4017
Echinococcus granulosus tm gpcr rhodopsin 0.0033 0.0074 0.0073
Echinococcus granulosus excitatory amino acid transporter 2 0.0975 0.3981 0.3981
Trypanosoma brucei PAB1-binding protein , putative 0.005 0.0142 0.0982
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0033 0.0074 0.0073
Loa Loa (eye worm) hypothetical protein 0.0053 0.0154 0.0263
Echinococcus granulosus EGFP:Bcl2 fusion protein 0.008 0.0267 0.0266
Loa Loa (eye worm) unidentified vitellogenin-linked transcript protein 6 0.0033 0.0074 0.0125
Toxoplasma gondii melibiase subfamily protein 0.0075 0.0246 0.216
Echinococcus granulosus sex peptide receptor 0.0033 0.0074 0.0073
Leishmania major hypothetical protein, conserved 0.0023 0.0033 0.006
Brugia malayi G protein-coupled receptor 0.0033 0.0074 0.0186
Brugia malayi Nuclear hormone receptor family member nhr-19 0.003 0.006 0.015
Mycobacterium ulcerans cytochrome P450 187A4 Cyp187A4 0.0027 0.0046 0.0077
Loa Loa (eye worm) hypothetical protein 0.0041 0.0105 0.0179
Echinococcus multilocularis pyroglutamylated rfamide peptide receptor 0.0033 0.0074 0.0073
Loa Loa (eye worm) heterochromatin protein 1 0.0067 0.0214 0.0367
Echinococcus multilocularis rhodopsin orphan GPCR 0.0033 0.0074 0.0073
Mycobacterium tuberculosis Probable membrane NADH dehydrogenase NdhA 0.0091 0.0314 0.0618
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0035 0.0083 0.0097
Schistosoma mansoni alpha-galactosidase/alpha-n-acetylgalactosaminidase 0.005 0.0142 0.0141
Entamoeba histolytica hypothetical protein 0.0026 0.0045 0.0009
Trichomonas vaginalis conserved hypothetical protein 0.0027 0.0046 0.0032
Trichomonas vaginalis CAMK family protein kinase 0.0088 0.0302 0.0488
Echinococcus granulosus DNA apurinic or apyrimidinic site lyase 0.0038 0.0093 0.0091
Mycobacterium ulcerans aldehyde dehydrogenase 0.0267 0.1043 0.3785
Schistosoma mansoni amine GPCR 0.0033 0.0074 0.0073
Plasmodium vivax transportin, putative 0.0025 0.004 0.0631
Loa Loa (eye worm) histone methyltransferase 0.0036 0.0083 0.0141
Loa Loa (eye worm) hypothetical protein 0.003 0.006 0.0101
Schistosoma mansoni opsin-like receptor 0.0033 0.0074 0.0073
Echinococcus multilocularis serotonin receptor 0.0033 0.0074 0.0073
Giardia lamblia Endonuclease/Exonuclease/phosphatase 0.0038 0.0093 0.0119
Loa Loa (eye worm) PHD-finger family protein 0.0027 0.0049 0.0082
Brugia malayi RNA binding protein 0.0054 0.0158 0.0397
Schistosoma mansoni sex comb on midleg homolog 0.0102 0.0359 0.0357
Loa Loa (eye worm) hypothetical protein 0.0033 0.0074 0.0125
Loa Loa (eye worm) hypothetical protein 0.0033 0.0074 0.0125
Toxoplasma gondii ATP-dependent DNA helicase, RecQ family protein 0.0024 0.0034 0.0082
Trichomonas vaginalis ran, putative 0.0081 0.0271 0.0434
Trichomonas vaginalis penicillin-binding protein, putative 0.0167 0.0631 0.1076
Plasmodium falciparum thioredoxin reductase 0.004 0.0102 0.2093
Loa Loa (eye worm) jmjC domain-containing protein 0.0095 0.0331 0.0569
Onchocerca volvulus Pyruvate kinase homolog 0.0068 0.0217 0.0427
Schistosoma mansoni pyruvate kinase 0.0068 0.0217 0.0215
Schistosoma mansoni DNA polymerase IV / kappa 0.0022 0.0026 0.0024
Loa Loa (eye worm) hypothetical protein 0.0033 0.0074 0.0125
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0018 0.0009 0.0007
Echinococcus multilocularis terminal deoxycytidyl transferase rev1 0.007 0.0226 0.0224
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0101 0.0355 0.0584
Echinococcus multilocularis thioredoxin glutathione reductase 0.0041 0.0104 0.0103
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0033 0.0074 0.0073
Toxoplasma gondii HEAT repeat-containing protein 0.0025 0.004 0.0138
Loa Loa (eye worm) G-protein coupled receptor 0.0033 0.0074 0.0125
Echinococcus granulosus Peptidase C19 ubiquitin carboxyl terminal hydrolase 2 0.0101 0.0355 0.0354
Echinococcus granulosus translational activator gcn1 0.0025 0.004 0.0038
Trypanosoma brucei ULK family serine/threonine-protein kinase, putative 0.0025 0.0041 0.0129
Trypanosoma brucei unspecified product 0.0048 0.0136 0.0931
Schistosoma mansoni FTZ-F1 nuclear receptor-like protein 0.003 0.006 0.0059
Loa Loa (eye worm) hypothetical protein 0.018 0.0681 0.1171
Loa Loa (eye worm) CHromoDomain protein family member 0.0019 0.0013 0.002
Plasmodium falciparum ATP-dependent DNA helicase Q1 0.0024 0.0034 0.0703
Echinococcus multilocularis g protein linked acetylcholine receptor gar 2a 0.0033 0.0074 0.0073
Trichomonas vaginalis ap endonuclease, putative 0.0038 0.0093 0.0115
Schistosoma mansoni chromodomain helicase DNA binding protein 0.0019 0.0013 0.0012
Loa Loa (eye worm) jmjC domain-containing protein 0.0023 0.0033 0.0054
Echinococcus granulosus neuropeptides capa receptor 0.0033 0.0074 0.0073
Mycobacterium tuberculosis Probable NADH dehydrogenase Ndh 0.0091 0.0314 0.0618
Echinococcus multilocularis rhodopsin orphan GPCR 0.0033 0.0074 0.0073
Brugia malayi hypothetical protein 0.0033 0.0074 0.0186
Plasmodium falciparum histone acetyltransferase GCN5 0.007 0.0226 0.466
Schistosoma mansoni hypothetical protein 0.0627 0.2539 0.2538
Loa Loa (eye worm) hypothetical protein 0.0133 0.0486 0.0834
Loa Loa (eye worm) apoptosis regulator protein 0.008 0.0267 0.0458
Echinococcus multilocularis beta LACTamase domain containing family member 0.0167 0.0631 0.0629
Schistosoma mansoni transcription factor LCR-F1 0.0026 0.0045 0.0043
Schistosoma mansoni neuropeptide receptor 0.0033 0.0074 0.0073
Loa Loa (eye worm) hypothetical protein 0.0033 0.0074 0.0125
Trichomonas vaginalis esterase, putative 0.0167 0.0631 0.1076
Trichomonas vaginalis CAMK family protein kinase 0.0088 0.0302 0.0488
Brugia malayi Nuclear hormone receptor family member nhr-25 0.003 0.006 0.015
Mycobacterium tuberculosis Probable hydrolase 0.0167 0.0631 0.135
Echinococcus multilocularis Transcription factor, JmjC domain containing protein 0.0144 0.0533 0.0532
Echinococcus multilocularis fmrfamide receptor 0.0033 0.0074 0.0073
Leishmania major apurinic/apyrimidinic endonuclease-redox protein 0.0038 0.0093 0.0566
Trichomonas vaginalis Importin beta-1 subunit, putative 0.0107 0.0382 0.0631
Brugia malayi gonadotropin-releasing hormone receptor 2 0.0033 0.0074 0.0186
Echinococcus multilocularis thyroid hormone receptor alpha 0.003 0.006 0.0059
Echinococcus multilocularis histone lysine N methyltransferase MLL3 0.0036 0.0083 0.0082
Trichomonas vaginalis DNA helicase recq1, putative 0.0037 0.0089 0.0108
Trypanosoma brucei mitochondrial DNA polymerase beta-PAK 0.0145 0.0537 0.4331
Brugia malayi C2-HC type zinc finger protein C.e-MyT1 0.0116 0.0417 0.1048
Trypanosoma brucei DNA polymerase kappa, putative 0.007 0.0226 0.1694
Loa Loa (eye worm) hypothetical protein 0.0033 0.0074 0.0125
Brugia malayi beta-lactamase family protein 0.0167 0.0631 0.1584
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0033 0.0074 0.0073
Loa Loa (eye worm) cytochrome P450 0.0027 0.0046 0.0078
Loa Loa (eye worm) pyruvate kinase 0.0068 0.0217 0.0371
Schistosoma mansoni phd/f-box containing protein 0.0023 0.0033 0.0031
Echinococcus granulosus pyruvate kinase 0.0035 0.008 0.0079
Onchocerca volvulus 0.0108 0.0383 0.0851
Brugia malayi GTP-binding regulatory protein Gs alpha-S chain, putative 0.0335 0.1326 0.3331
Trichomonas vaginalis D-aminoacylase, putative 0.0167 0.0631 0.1076
Entamoeba histolytica hypothetical protein 0.0026 0.0045 0.0009
Schistosoma mansoni hypothetical protein 0.0033 0.0074 0.0073
Echinococcus granulosus neuropeptide s receptor 0.0813 0.331 0.3309
Brugia malayi hypothetical protein 0.0141 0.0521 0.1309
Echinococcus granulosus dna polymerase eta 0.0137 0.0503 0.0502
Onchocerca volvulus 0.0033 0.0074 0.0064
Mycobacterium leprae Probable pyruvate kinase PykA 0.0068 0.0217 0.0638
Echinococcus granulosus g protein coupled receptor 0.0033 0.0074 0.0073
Loa Loa (eye worm) neuropeptide F receptor 0.0033 0.0074 0.0125
Loa Loa (eye worm) mbt repeat family protein 0.0102 0.0359 0.0616
Echinococcus multilocularis lysine specific demethylase 5A 0.0088 0.03 0.0298
Schistosoma mansoni biogenic amine receptor 0.0033 0.0074 0.0073
Echinococcus multilocularis excitatory amino acid transporter 2 0.0975 0.3981 0.3981
Echinococcus granulosus endonuclease exonuclease phosphatase 0.0409 0.1634 0.1633
Schistosoma mansoni rab geranylgeranyl transferase alpha subunit 0.007 0.0226 0.0224
Mycobacterium tuberculosis Probable fructose-bisphosphate aldolase Fba 0.067 0.2714 0.6163
Echinococcus granulosus tm gpcr rhodopsin 0.0033 0.0074 0.0073
Trypanosoma cruzi cytochrome P450, putative 0.0049 0.0141 0.0972
Leishmania major hypothetical protein, conserved 0.005 0.0142 0.0982
Brugia malayi neuropeptide F receptor 0.0033 0.0074 0.0186
Toxoplasma gondii PHD-finger domain-containing protein 0.0027 0.0049 0.0225
Trichomonas vaginalis conserved hypothetical protein 0.0024 0.0036 0.0013
Trichomonas vaginalis hypothetical protein 0.0025 0.004 0.002

Activities

Activity type Activity value Assay description Source Reference
Inhibition (functional) = 30 % Inhibition of coupled transcription/translation in Staphylococcus aureus at 100 uM ChEMBL. 17027262
MIC (functional) > 128 ug ml-1 Antibacterial activity against Staphylococcus aureus ChEMBL. 17027262

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
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External resources for this compound

Bibliographic References

1 literature reference was collected for this gene.

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