Detailed information for compound 415992

Basic information

Technical information
  • TDR Targets ID: 415992
  • Name: N-(2,3-dihydro-1H-inden-2-yl)-N'-hydroxypropa nediamide
  • MW: 234.251 | Formula: C12H14N2O3
  • H donors: 3 H acceptors: 3 LogP: 1.1 Rotable bonds: 5
    Rule of 5 violations (Lipinski): 1
  • SMILES: ONC(=O)CC(=O)NC1Cc2c(C1)cccc2
  • InChi: 1S/C12H14N2O3/c15-11(7-12(16)14-17)13-10-5-8-3-1-2-4-9(8)6-10/h1-4,10,17H,5-7H2,(H,13,15)(H,14,16)
  • InChiKey: CDKFJWIDMNQCQT-UHFFFAOYSA-N  


Substructure search Similarity search

Network

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Synonyms

  • 3-(hydroxyamino)-N-indan-2-yl-3-oxo-propanamide
  • 3-(hydroxyamino)-N-(2-indanyl)-3-oxopropanamide
  • N-(2,3-dihydro-1H-inden-2-yl)-N'-hydroxy-propanediamide
  • 3-(hydroxyamino)-N-indan-2-yl-3-keto-propionamide

Targets

Known targets for this compound

No curated genes were found associated with this compound

Predicted pathogen targets for this compound

By orthology
No druggable targets predicted by orthology data
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Trypanosoma brucei hypothetical protein, conserved 0.0035 0.0254 0.0573
Loa Loa (eye worm) hypothetical protein 0.0018 0.0031 0.0069
Brugia malayi latrophilin 2 splice variant baaae 0.0033 0.023 0.0519
Echinococcus granulosus biogenic amine 5HT receptor 0.0018 0.0031 0.0035
Brugia malayi nuclear receptor RXR 0.0019 0.0047 0.0107
Schistosoma mansoni carbonic anhydrase-related 0.0117 0.1323 0.156
Schistosoma mansoni hypothetical protein 0.0035 0.0254 0.03
Mycobacterium tuberculosis Probable hydrolase 0.0035 0.0254 0.0704
Loa Loa (eye worm) hypothetical protein 0.0021 0.0077 0.0174
Schistosoma mansoni P2X receptor subunit 0.0291 0.3585 0.4227
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.004 0.0323 0.0728
Echinococcus multilocularis nuclear receptor nhr 48 0.0019 0.0047 0.0047
Trichomonas vaginalis CAMK family protein kinase 0.0045 0.039 0.1006
Echinococcus multilocularis p2X purinoceptor 4 0.0291 0.3585 0.3585
Onchocerca volvulus 0.0055 0.0522 0.1786
Loa Loa (eye worm) hypothetical protein 0.0018 0.0031 0.0069
Echinococcus multilocularis rhodopsin orphan GPCR 0.0018 0.0031 0.0031
Brugia malayi hypothetical protein 0.0021 0.0077 0.0174
Leishmania major 4-coumarate:coa ligase-like protein 0.0023 0.01 0.0224
Loa Loa (eye worm) hypothetical protein 0.0018 0.0031 0.0069
Trypanosoma cruzi myo-inositol-1(or 4)-monophosphatase 1, putative 0.0036 0.0266 0.06
Echinococcus granulosus neuroligin 0.0055 0.0522 0.0599
Trichomonas vaginalis CAMK family protein kinase 0.0091 0.099 0.2753
Schistosoma mansoni peptide (allatostatin)-like receptor 0.0018 0.0031 0.0036
Echinococcus granulosus carbonic anhydrase 0.0117 0.1323 0.1519
Trypanosoma brucei DNA polymerase kappa, putative 0.0019 0.0044 0.0099
Loa Loa (eye worm) 5-hydroxytryptamine 2C receptor 0.0018 0.0031 0.0069
Echinococcus granulosus g-protein coupled receptor 0.0018 0.0031 0.0035
Brugia malayi Corticotropin releasing factor receptor 2 precursor, putative 0.0048 0.0429 0.0967
Echinococcus granulosus Nuclear hormone receptor HR96 0.0019 0.0047 0.0054
Loa Loa (eye worm) glutaminase 2 0.0265 0.3255 0.7344
Echinococcus granulosus dna polymerase eta 0.0019 0.0044 0.0051
Echinococcus multilocularis FTZ F1 alpha 0.004 0.0323 0.0323
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0035 0.0254 0.03
Entamoeba histolytica acyl-coA synthetase, putative 0.0023 0.01 0.0134
Loa Loa (eye worm) hypothetical protein 0.0018 0.0031 0.0069
Schistosoma mansoni terminal deoxycytidyl transferase 0.0019 0.0044 0.0052
Loa Loa (eye worm) hypothetical protein 0.0035 0.0254 0.0574
Schistosoma mansoni hypothetical protein 0.0164 0.1933 0.2279
Echinococcus granulosus carbonic anhydrase II 0.0216 0.2611 0.2998
Loa Loa (eye worm) DR-78 0.0019 0.0047 0.0107
Loa Loa (eye worm) hypothetical protein 0.004 0.0323 0.0728
Mycobacterium ulcerans acyl-CoA synthetase 0.0023 0.01 0.0274
Echinococcus granulosus rhodopsin orphan GPCR 0.0018 0.0031 0.0035
Mycobacterium ulcerans lipase LipD 0.0035 0.0254 0.0703
Echinococcus multilocularis tachykinin peptides receptor 99D 0.0018 0.0031 0.0031
Schistosoma mansoni growth hormone secretagogue receptor 0.0018 0.0031 0.0036
Schistosoma mansoni neuroligin 3 (S09 family) 0.0055 0.0522 0.0615
Giardia lamblia DNA repair protein RAD52 0.0336 0.4174 1
Trypanosoma brucei ubiquitin-activating enzyme E1, putative 0.0031 0.0201 0.0452
Trypanosoma brucei DNA polymerase kappa, putative 0.0019 0.0044 0.0099
Echinococcus granulosus p2X purinoceptor 4 0.0291 0.3585 0.4116
Echinococcus multilocularis growth hormone secretagogue receptor type 1 0.0018 0.0031 0.0031
Brugia malayi nuclear receptor NHR-88 0.004 0.0323 0.0728
Brugia malayi Ulp1 protease family, C-terminal catalytic domain containing protein 0.0064 0.0637 0.1437
Echinococcus multilocularis survival motor neuron protein 1 0.0228 0.2776 0.2776
Schistosoma mansoni hypothetical protein 0.0018 0.0031 0.0036
Echinococcus granulosus g protein coupled receptor 0.0018 0.0031 0.0035
Echinococcus multilocularis Nuclear hormone receptor HR96 0.0019 0.0047 0.0047
Echinococcus multilocularis g-protein coupled receptor 0.0018 0.0031 0.0031
Onchocerca volvulus 0.0026 0.0141 0.04
Brugia malayi hypothetical protein 0.0118 0.1342 0.3028
Entamoeba histolytica hypothetical protein 0.0035 0.0254 0.0508
Loa Loa (eye worm) cytochrome P450 family protein 0.0015 0.0001 0.0002
Trichomonas vaginalis flap endonuclease-1, putative 0.0025 0.0129 0.0247
Loa Loa (eye worm) hypothetical protein 0.0356 0.4433 1
Echinococcus multilocularis acetylcholinesterase 0.0327 0.4064 0.4064
Trypanosoma brucei DNA polymerase kappa, putative 0.0019 0.0044 0.0099
Trichomonas vaginalis spcc417.12 protein, putative 0.0055 0.0522 0.1391
Brugia malayi Flap endonuclease-1 0.0025 0.0129 0.0291
Loa Loa (eye worm) PLK/PLK1 protein kinase 0.0091 0.099 0.2233
Loa Loa (eye worm) G-protein-linked acetylcholine receptor protein 2 0.0018 0.0031 0.0069
Schistosoma mansoni opsin-like receptor 0.0018 0.0031 0.0036
Brugia malayi tailless protein 0.0019 0.0047 0.0107
Schistosoma mansoni nuclear receptor 2DBD-gamma 0.004 0.0323 0.0381
Schistosoma mansoni photoreceptor-specific nuclear receptor related 0.004 0.0323 0.0381
Echinococcus granulosus rhodopsin orphan GPCR 0.0018 0.0031 0.0035
Loa Loa (eye worm) beta-lactamase 0.0035 0.0254 0.0574
Echinococcus granulosus nuclear receptor subfamily 4 group A 0.0019 0.0047 0.0054
Trypanosoma brucei DNA polymerase IV, putative 0.0019 0.0044 0.0099
Trypanosoma cruzi myo-inositol-1(or 4)-monophosphatase 1, putative 0.0036 0.0266 0.06
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0044 0.0377 0.0444
Schistosoma mansoni peptide (FMRFamide/somatostatin)-like receptor 0.0018 0.0031 0.0036
Echinococcus granulosus neuropeptide FF receptor 2 0.0018 0.0031 0.0035
Brugia malayi Cytochrome P450 family protein 0.0015 0.0001 0.0002
Echinococcus multilocularis peptide (allatostatin:somatostatin) 0.0018 0.0031 0.0031
Mycobacterium tuberculosis Fatty-acid-AMP ligase FadD30 (fatty-acid-AMP synthetase) (fatty-acid-AMP synthase) 0.0017 0.0024 0.0067
Echinococcus granulosus geminin 0.0164 0.1933 0.2219
Schistosoma mansoni nuclear hormone receptor nor-1/nor-2 0.004 0.0323 0.0381
Echinococcus multilocularis allatostatin A receptor 0.0018 0.0031 0.0031
Echinococcus multilocularis histone lysine methyltransferase setb histone lysine methyltransferase eggless 0.0029 0.0177 0.0177
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0018 0.0031 0.0036
Echinococcus granulosus neuropeptide Y receptor 0.0018 0.0031 0.0035
Trichomonas vaginalis esterase, putative 0.0035 0.0254 0.0612
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0018 0.0031 0.0036
Brugia malayi photoreceptor-specific nuclear receptor 0.004 0.0323 0.0728
Loa Loa (eye worm) TYRA-2 protein 0.0018 0.0031 0.0069
Echinococcus multilocularis carbonic anhydrase 0.0117 0.1323 0.1323
Leishmania major DNA polymerase kappa, putative,DNA polymerase IV, putative 0.0019 0.0044 0.0099
Entamoeba histolytica Flap nuclease, putative 0.0025 0.0129 0.0205
Loa Loa (eye worm) nuclear hormone receptor family member nhr-41 0.004 0.0323 0.0728
Leishmania major DNA polymerase eta, putative 0.0019 0.0044 0.0099
Loa Loa (eye worm) eukaryotic-type carbonic anhydrase 0.0216 0.2611 0.5891
Entamoeba histolytica fructose-1,6-bisphosphate aldolase, putative 0.0282 0.3477 0.8314
Echinococcus multilocularis rhodopsin orphan GPCR 0.0018 0.0031 0.0031
Schistosoma mansoni family S9 non-peptidase homologue (S09 family) 0.0055 0.0522 0.0615
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0019 0.0047 0.0054
Schistosoma mansoni hypothetical protein 0.0047 0.0408 0.0481
Echinococcus multilocularis neuropeptides capa receptor 0.0018 0.0031 0.0031
Plasmodium falciparum carbonic anhydrase 0.0117 0.1323 1
Trypanosoma brucei DNA polymerase kappa, putative 0.0019 0.0044 0.0099
Loa Loa (eye worm) hypothetical protein 0.0118 0.1342 0.3028
Plasmodium vivax ubiquitin activating enzyme, putative 0.0047 0.0408 1
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.004 0.0323 0.0323
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0018 0.0031 0.0036
Schistosoma mansoni lamin 0.0026 0.0141 0.0166
Schistosoma mansoni amine GPCR 0.0018 0.0031 0.0036
Echinococcus multilocularis geminin 0.0164 0.1933 0.1933
Echinococcus multilocularis carbonic anhydrase 0.0117 0.1323 0.1323
Echinococcus granulosus neuropeptide receptor 0.0018 0.0031 0.0035
Echinococcus granulosus family S9 non peptidase ue S09 family 0.0055 0.0522 0.0599
Trypanosoma cruzi PAB1-binding protein , putative 0.0024 0.012 0.027
Echinococcus multilocularis thyrotropin releasing hormone receptor 0.0018 0.0031 0.0031
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD35 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0016 0.0012 0.0033
Loa Loa (eye worm) hypothetical protein 0.0055 0.0522 0.1177
Loa Loa (eye worm) hypothetical protein 0.004 0.0323 0.0728
Schistosoma mansoni neuropeptide F-like receptor 0.0018 0.0031 0.0036
Trypanosoma cruzi flap endonuclease-1 (FEN-1), putative 0.0025 0.0129 0.0291
Echinococcus granulosus g protein linked acetylcholine receptor gar 2a 0.0018 0.0031 0.0035
Schistosoma mansoni hypothetical protein 0.0018 0.0031 0.0036
Onchocerca volvulus Protein ultraspiracle homolog 0.004 0.0323 0.1062
Mycobacterium leprae conserved hypothetical protein 0.0035 0.0254 0.0441
Loa Loa (eye worm) hypothetical protein 0.0018 0.0031 0.0069
Loa Loa (eye worm) hypothetical protein 0.0018 0.0031 0.0069
Brugia malayi hypothetical protein 0.0018 0.0031 0.0069
Brugia malayi nuclear hormone receptor family member nhr-6 0.0019 0.0047 0.0107
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0035 0.0254 0.03
Brugia malayi hypothetical protein 0.0228 0.2776 0.6262
Leishmania major C-8 sterol isomerase-like protein 0.0356 0.4433 1
Loa Loa (eye worm) nuclear receptor nhr-7B 0.0019 0.0047 0.0107
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0029 0.0177 0.0209
Brugia malayi G-protein-linked acetylcholine receptor protein 2, putative 0.0018 0.0031 0.0069
Echinococcus granulosus alpha 1A adrenergic receptor 0.0018 0.0031 0.0035
Echinococcus multilocularis neuroligin 0.0055 0.0522 0.0522
Loa Loa (eye worm) unidentified vitellogenin-linked transcript protein 6 0.0018 0.0031 0.0069
Toxoplasma gondii hypothetical protein 0.0117 0.1323 1
Echinococcus granulosus peptide allatostatin:somatostatin 0.0018 0.0031 0.0035
Schistosoma mansoni adenoreceptor 0.0018 0.0031 0.0036
Echinococcus multilocularis acetylcholinesterase 0.0327 0.4064 0.4064
Brugia malayi ImpB/MucB/SamB family protein 0.0019 0.0044 0.01
Loa Loa (eye worm) nuclear hormone receptor family member nhr-49 0.004 0.0323 0.0728
Plasmodium vivax SET domain protein, putative 0.0029 0.0177 0.4336
Mycobacterium tuberculosis Possible penicillin-binding protein 0.0222 0.2695 0.7464
Brugia malayi Serotonin receptor 0.0018 0.0031 0.0069
Trichomonas vaginalis penicillin-binding protein, putative 0.0035 0.0254 0.0612
Loa Loa (eye worm) hypothetical protein 0.0017 0.0024 0.0055
Trypanosoma brucei DNA polymerase kappa, putative 0.0019 0.0044 0.0099
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0018 0.0031 0.0036
Trypanosoma cruzi cytochrome P450, putative 0.0015 0.0001 0.0001
Trypanosoma brucei unspecified product 0.0019 0.0044 0.0099
Plasmodium vivax SUMO-activating enzyme subunit 2, putative 0.0031 0.0201 0.4913
Trypanosoma brucei DNA polymerase IV, putative 0.0019 0.0044 0.0099
Loa Loa (eye worm) gonadotropin-releasing hormone receptor 2 0.0018 0.0031 0.0069
Schistosoma mansoni nuclear receptor 0.0019 0.0047 0.0056
Brugia malayi neuropeptide F receptor 0.0018 0.0031 0.0069
Brugia malayi G protein-coupled receptor F59B2.13 0.0018 0.0031 0.0069
Brugia malayi Nuclear hormone receptor family member nhr-3 0.004 0.0323 0.0728
Loa Loa (eye worm) GTP-binding regulatory protein Gs alpha-S chain 0.0044 0.0377 0.085
Echinococcus granulosus neuropeptide Y receptor 0.0018 0.0031 0.0035
Loa Loa (eye worm) hypothetical protein 0.0018 0.0031 0.0069
Echinococcus multilocularis histone lysine N methyltransferase SETMAR 0.0029 0.0177 0.0177
Schistosoma mansoni opsin-like receptor 0.0018 0.0031 0.0036
Schistosoma mansoni histone-lysine n-methyltransferase suv9 0.0029 0.0177 0.0209
Echinococcus granulosus pyroglutamylated rfamide peptide receptor 0.0018 0.0031 0.0035
Trypanosoma cruzi DNA polymerase kappa, putative 0.0019 0.0044 0.0099
Echinococcus multilocularis rhodopsin orphan GPCR 0.0018 0.0031 0.0031
Echinococcus multilocularis dna polymerase kappa 0.0019 0.0044 0.0044
Mycobacterium tuberculosis Probable lipase LipD 0.0035 0.0254 0.0704
Echinococcus granulosus survival motor neuron protein 1 0.0228 0.2776 0.3187
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0282 0.3477 1
Brugia malayi hypothetical protein 0.0018 0.0031 0.0069
Echinococcus granulosus tm gpcr rhodopsin 0.0018 0.0031 0.0035
Schistosoma mansoni carbonic anhydrase II (carbonate dehydratase II) 0.0216 0.2611 0.3079
Echinococcus multilocularis G protein coupled receptor 139 0.0018 0.0031 0.0031
Brugia malayi beta-lactamase 0.0035 0.0254 0.0574
Brugia malayi Unidentified vitellogenin-linked transcript protein 6, putative 0.0018 0.0031 0.0069
Mycobacterium tuberculosis Conserved protein 0.0035 0.0254 0.0704
Echinococcus granulosus carboxylesterase 5A 0.0327 0.4064 0.4666
Brugia malayi Intermediate filament tail domain containing protein 0.0026 0.0141 0.0318
Brugia malayi hypothetical protein 0.0018 0.0031 0.0069
Echinococcus granulosus lamin 0.0026 0.0141 0.0162
Brugia malayi hypothetical protein 0.0019 0.0047 0.0107
Echinococcus multilocularis beta LACTamase domain containing family member 0.0035 0.0254 0.0254
Loa Loa (eye worm) hypothetical protein 0.0023 0.01 0.0225
Leishmania major ubiquitin-activating enzyme-like protein 0.0031 0.0201 0.0452
Mycobacterium tuberculosis Possible DNA-damage-inducible protein P DinP (DNA polymerase V) (pol IV 2) (DNA nucleotidyltransferase (DNA-directed)) 0.0019 0.0044 0.0122
Brugia malayi orphan nuclear receptor NR2E1 0.0019 0.0047 0.0107
Entamoeba histolytica acyl-CoA synthetase, putative 0.0023 0.01 0.0134
Echinococcus granulosus muscleblind protein 0.0144 0.168 0.1929
Brugia malayi Carboxylesterase family protein 0.0055 0.0522 0.1177
Schistosoma mansoni microtubule-associated protein tau 0.0667 0.848 1
Trypanosoma cruzi polo-like protein kinase, putative 0.0091 0.099 0.2232
Echinococcus multilocularis Nuclear hormone receptor family member nhr 41 0.004 0.0323 0.0323
Brugia malayi Melatonin receptor type 1A 0.0018 0.0031 0.0069
Loa Loa (eye worm) nuclear hormone receptor family member nhr-1 0.004 0.0323 0.0728
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0018 0.0031 0.0036
Echinococcus granulosus BC026374 protein S09 family 0.0055 0.0522 0.0599
Loa Loa (eye worm) inositol-1 0.0036 0.0266 0.06
Brugia malayi AKH receptor 0.0018 0.0031 0.0069
Onchocerca volvulus 0.004 0.0323 0.1062
Schistosoma mansoni nuclear receptor 0.0019 0.0047 0.0056
Loa Loa (eye worm) hypothetical protein 0.0018 0.0031 0.0069
Entamoeba histolytica myo-inositol monophosphatase, putative 0.0036 0.0266 0.0537
Loa Loa (eye worm) hypothetical protein 0.004 0.0323 0.0728
Brugia malayi Eukaryotic-type carbonic anhydrase family protein 0.0117 0.1323 0.2985
Echinococcus multilocularis family S9 non peptidase ue (S09 family) 0.0055 0.0522 0.0522
Echinococcus granulosus hypothetical protein 0.0684 0.871 1
Brugia malayi Nuclear hormone receptor E75 0.0019 0.0047 0.0107
Trichomonas vaginalis penicillin-binding protein, putative 0.0035 0.0254 0.0612
Echinococcus granulosus nuclear receptor 2DBD gamma 0.004 0.0323 0.0371
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0029 0.0177 0.0209
Loa Loa (eye worm) nuclear hormone receptor family member nhr-31 0.004 0.0323 0.0728
Echinococcus multilocularis neuropeptides capa receptor 0.0018 0.0031 0.0031
Echinococcus multilocularis g protein coupled receptor 0.0018 0.0031 0.0031
Loa Loa (eye worm) hypothetical protein 0.0018 0.0031 0.0069
Loa Loa (eye worm) hypothetical protein 0.0117 0.1323 0.2985
Brugia malayi Carbonic anhydrase like protein 2 precursor 0.0117 0.1323 0.2985
Echinococcus granulosus rhodopsin orphan GPCR 0.0018 0.0031 0.0035
Mycobacterium ulcerans long-chain-fatty-acid-CoA ligase 0.0023 0.01 0.0274
Plasmodium vivax flap endonuclease 1, putative 0.0025 0.0129 0.3161
Treponema pallidum cell division protein FtsZ 0.0293 0.361 1
Loa Loa (eye worm) hypothetical protein 0.0017 0.0024 0.0055
Brugia malayi hypothetical protein 0.0035 0.0254 0.0573
Echinococcus multilocularis rhodopsin orphan GPCR 0.0018 0.0031 0.0031
Brugia malayi Serotonin/octopamine receptor family protein 7 0.0018 0.0031 0.0069
Schistosoma mansoni thyroid hormone receptor 0.004 0.0323 0.0381
Echinococcus granulosus flap endonuclease 1 0.0025 0.0129 0.0148
Loa Loa (eye worm) hypothetical protein 0.0117 0.1323 0.2985
Loa Loa (eye worm) hypothetical protein 0.0019 0.0047 0.0107
Onchocerca volvulus 0.0035 0.0254 0.0813
Loa Loa (eye worm) carbonic anhydrase 3 0.0216 0.2611 0.5891
Mycobacterium leprae possible inositol monophosphatase SubH (IMPase) (inositol-1-phosphatase) (I-1-Pase ). 0.0032 0.0217 0.0335
Echinococcus multilocularis rhodopsin orphan GPCR 0.0018 0.0031 0.0031
Echinococcus granulosus serine:threonine protein kinase PLK1 0.0091 0.099 0.1136
Onchocerca volvulus 0.0055 0.0522 0.1786
Brugia malayi steroid hormone receptor 0.004 0.0323 0.0728
Schistosoma mansoni hypothetical protein 0.0033 0.023 0.0271
Brugia malayi Carboxylesterase family protein 0.0327 0.4064 0.9169
Schistosoma mansoni retinoid-x-receptor (RXR) 0.0021 0.0077 0.0091
Leishmania major 4-coumarate:coa ligase-like protein 0.0023 0.01 0.0224
Brugia malayi Nuclear hormone receptor family member nhr-1 0.004 0.0323 0.0728
Entamoeba histolytica tumor susceptibility gene 101 protein, putative 0.0046 0.0397 0.0853
Onchocerca volvulus 0.0055 0.0522 0.1786
Mycobacterium leprae cell division protein FtsZ 0.0293 0.361 1
Mycobacterium ulcerans acyl-CoA synthetase 0.0023 0.01 0.0274
Schistosoma mansoni neuropeptide receptor 0.0018 0.0031 0.0036
Brugia malayi Eukaryotic-type carbonic anhydrase family protein 0.0117 0.1323 0.2985
Trypanosoma brucei DNA polymerase kappa, putative 0.0019 0.0044 0.0099
Schistosoma mansoni biogenic amine receptor 0.0018 0.0031 0.0036
Loa Loa (eye worm) hypothetical protein 0.0019 0.0047 0.0107
Loa Loa (eye worm) hypothetical protein 0.004 0.0323 0.0728
Loa Loa (eye worm) carboxylesterase 0.0055 0.0522 0.1177
Schistosoma mansoni ubiquitin-activating enzyme E1b 0.0031 0.0201 0.0236
Brugia malayi Nuclear hormone receptor-like 1 0.0021 0.0077 0.0174
Mycobacterium tuberculosis POSSIBLE PARA-NITROBENZYL ESTERASE (FRAGMENT) 0.0055 0.0522 0.1445
Trypanosoma cruzi Vps23 core domain containing protein, putative 0.0021 0.0081 0.0183
Loa Loa (eye worm) hypothetical protein 0.0018 0.0031 0.0069
Echinococcus multilocularis microtubule associated protein 2 0.0667 0.848 0.848
Schistosoma mansoni acetylcholinesterase 0.0055 0.0522 0.0615
Trypanosoma cruzi hypothetical protein, conserved 0.0035 0.0254 0.0573
Loa Loa (eye worm) hypothetical protein 0.0021 0.0077 0.0174
Echinococcus granulosus sumo-activating enzyme subunit 2 0.0031 0.0201 0.023
Echinococcus multilocularis G-protein coupled receptor, putative 0.0018 0.0031 0.0031
Echinococcus multilocularis muscleblind protein 1 0.0144 0.168 0.168
Echinococcus granulosus nuclear receptor nhr 48 0.0019 0.0047 0.0054
Loa Loa (eye worm) hypothetical protein 0.0019 0.0047 0.0107
Trypanosoma cruzi ubiquitin-activating enzyme, putative 0.0026 0.0145 0.0326
Onchocerca volvulus 0.0047 0.0408 0.1372
Brugia malayi ORL1-like opioid receptor 0.0018 0.0031 0.0069
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD3 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0016 0.0012 0.0033
Echinococcus granulosus tm gpcr rhodopsin 0.0018 0.0031 0.0035
Schistosoma mansoni hypothetical protein 0.0117 0.1323 0.156
Loa Loa (eye worm) CYP4Cod1 0.0015 0.0001 0.0002
Leishmania major carbonic anhydrase-like protein 0.0216 0.2611 0.589
Brugia malayi Nuclear hormone receptor family member nhr-40 0.004 0.0323 0.0728
Loa Loa (eye worm) follicle stimulating hormone receptor 0.024 0.2924 0.6596
Schistosoma mansoni carbonic anhydrase II (carbonate dehydratase II) 0.0216 0.2611 0.3079
Loa Loa (eye worm) hypothetical protein 0.0026 0.0141 0.0318
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0018 0.0031 0.0036
Loa Loa (eye worm) hypothetical protein 0.0018 0.0031 0.0069
Brugia malayi Cell division protein ftsZ 0.014 0.1629 0.3674
Loa Loa (eye worm) hypothetical protein 0.0018 0.0031 0.0069
Echinococcus multilocularis dro:myosuppressin receptor 0.0018 0.0031 0.0031
Schistosoma mansoni biogenic amine (5HT) receptor 0.0018 0.0031 0.0036
Entamoeba histolytica Ulp1 protease family, C-terminal catalytic domain containing protein 0.0064 0.0637 0.1435
Plasmodium vivax ataxin-2 like protein, putative 0.0024 0.012 0.2939
Loa Loa (eye worm) hypothetical protein 0.0018 0.0031 0.0069
Trypanosoma brucei carbonic anhydrase-like protein 0.0216 0.2611 0.589
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0018 0.0031 0.0036
Loa Loa (eye worm) Ulp1 protease 0.0064 0.0637 0.1437
Trypanosoma cruzi C-8 sterol isomerase, putative 0.0356 0.4433 1
Brugia malayi gonadotropin-releasing hormone receptor 2 0.0018 0.0031 0.0069
Plasmodium falciparum ataxin-2 like protein, putative 0.0024 0.012 0.0905
Brugia malayi neuropeptide F receptor 0.0018 0.0031 0.0069
Brugia malayi putative neuropeptide receptor 0.0018 0.0031 0.0069
Echinococcus multilocularis carboxylesterase 5A 0.0327 0.4064 0.4064
Brugia malayi hypothetical protein 0.0021 0.0077 0.0174
Trichomonas vaginalis Sentrin-specific protease, putative 0.0064 0.0637 0.1726
Schistosoma mansoni flap endonuclease-1 0.0023 0.0098 0.0115
Loa Loa (eye worm) hypothetical protein 0.0055 0.0522 0.1177
Loa Loa (eye worm) hypothetical protein 0.0018 0.0031 0.0069
Loa Loa (eye worm) hypothetical protein 0.0018 0.0031 0.0069
Loa Loa (eye worm) hypothetical protein 0.0018 0.0031 0.0069
Echinococcus multilocularis neuropeptide s receptor 0.0462 0.5817 0.5817
Echinococcus multilocularis carbonic anhydrase II 0.0216 0.2611 0.2611
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0282 0.3477 1
Trypanosoma brucei C-8 sterol isomerase, putative 0.0356 0.4433 1
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0018 0.0031 0.0036
Trichomonas vaginalis carboxylesterase domain containing protein, putative 0.0055 0.0522 0.1391
Loa Loa (eye worm) hypothetical protein 0.004 0.0323 0.0728
Schistosoma mansoni ecdysone-induced protein 78c (dr-78) 0.0021 0.0077 0.0091
Echinococcus multilocularis muscleblind protein 0.0144 0.168 0.168
Schistosoma mansoni biogenic amine receptor 0.0018 0.0031 0.0036
Schistosoma mansoni sumo-1-activating enzyme E1a 0.0047 0.0408 0.0481
Brugia malayi Pre-SET motif family protein 0.0029 0.0177 0.0399
Trypanosoma brucei DNA polymerase eta, putative 0.0019 0.0044 0.0099
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0018 0.0031 0.0031
Loa Loa (eye worm) hypothetical protein 0.0055 0.0522 0.1177
Brugia malayi hypothetical protein 0.0067 0.0676 0.1526
Loa Loa (eye worm) hypothetical protein 0.0182 0.2169 0.4892
Schistosoma mansoni histamine h1 receptor 0.0018 0.0031 0.0036
Trypanosoma brucei DNA polymerase kappa, putative 0.0019 0.0044 0.0099
Mycobacterium tuberculosis Probable esterase/lipase LipP 0.0035 0.0254 0.0704
Trypanosoma cruzi carbonic anhydrase-like protein, putative 0.0216 0.2611 0.589
Brugia malayi follicle stimulating hormone receptor 0.024 0.2924 0.6596
Echinococcus multilocularis inositol monophosphatase 1 0.0036 0.0266 0.0266
Onchocerca volvulus 0.0019 0.0047 0.0061
Brugia malayi ecdysteroid receptor 0.004 0.0323 0.0728
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0029 0.0177 0.0209
Echinococcus granulosus inositol monophosphatase 1 0.0036 0.0266 0.0306
Plasmodium vivax hypothetical protein, conserved 0.0035 0.0254 0.6235
Echinococcus granulosus beta LACTamase domain containing family member 0.0035 0.0254 0.0292
Echinococcus multilocularis g protein coupled receptor 0.0018 0.0031 0.0031
Echinococcus multilocularis orexin receptor type 2 0.0018 0.0031 0.0031
Brugia malayi Carbonic anhydrase like protein 2 precursor 0.0117 0.1323 0.2985
Loa Loa (eye worm) hypothetical protein 0.0018 0.0031 0.0069
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0019 0.0047 0.0047
Onchocerca volvulus Nuclear receptor subfamily 6 group A member 1 homolog 0.0019 0.0047 0.0061
Echinococcus multilocularis ecdysone induced protein 78C 0.004 0.0323 0.0323
Loa Loa (eye worm) flap endonuclease-1 0.0025 0.0129 0.0291
Schistosoma mansoni thyroid hormone receptor 0.004 0.0323 0.0381
Loa Loa (eye worm) hypothetical protein 0.0144 0.168 0.3791
Onchocerca volvulus 0.0229 0.2781 1
Loa Loa (eye worm) hypothetical protein 0.0018 0.0031 0.0069
Mycobacterium leprae Probable lipase LipE 0.0035 0.0254 0.0441
Schistosoma mansoni P2X receptor subunit 0.0291 0.3585 0.4227
Schistosoma mansoni peptide (FMRFamide/somatostatin)-like receptor 0.0018 0.0031 0.0036
Loa Loa (eye worm) pre-SET domain-containing protein family protein 0.0201 0.2419 0.5457
Mycobacterium ulcerans fatty-acid-CoA ligase 0.0017 0.0024 0.0065
Schistosoma mansoni retinoic acid receptor RXR 0.004 0.0323 0.0381
Echinococcus granulosus G protein coupled 5 hydroxytryptamine receptor 0.0018 0.0031 0.0035
Schistosoma mansoni survival motor neuron protein 0.0047 0.0408 0.0481
Loa Loa (eye worm) hypothetical protein 0.0018 0.0031 0.0069
Schistosoma mansoni steroid hormone receptor ad4bp 0.004 0.0323 0.0381
Schistosoma mansoni hypothetical protein 0.0164 0.1933 0.2279
Loa Loa (eye worm) G-protein coupled receptor 0.0018 0.0031 0.0069
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0044 0.0377 0.0433
Echinococcus granulosus lamin dm0 0.0026 0.0141 0.0162
Echinococcus granulosus 5'partial|histone lysine N methyltransferase SETDB2 0.0028 0.0163 0.0187
Schistosoma mansoni family C48 unassigned peptidase (C48 family) 0.0064 0.0637 0.0751
Trypanosoma brucei DNA polymerase IV, putative 0.0019 0.0044 0.0099
Echinococcus multilocularis G protein coupled 5 hydroxytryptamine receptor 0.0018 0.0031 0.0031
Brugia malayi Pre-SET motif family protein 0.0201 0.2419 0.5457
Brugia malayi hypothetical protein 0.0016 0.0007 0.0016
Loa Loa (eye worm) hypothetical protein 0.0035 0.0254 0.0574
Loa Loa (eye worm) hypothetical protein 0.0055 0.0522 0.1177
Leishmania major DNA polymerase kappa, putative 0.0019 0.0044 0.0099
Brugia malayi Eukaryotic-type carbonic anhydrase family protein 0.0216 0.2611 0.5891
Loa Loa (eye worm) hypothetical protein 0.0019 0.0047 0.0107
Brugia malayi hypothetical protein 0.0018 0.0031 0.0069
Brugia malayi hypothetical protein 0.0019 0.0047 0.0107
Mycobacterium tuberculosis Inositol-1-monophosphatase SuhB 0.0032 0.0217 0.0602
Echinococcus multilocularis SUMO activating enzyme subunit 1 0.0047 0.0408 0.0408
Loa Loa (eye worm) acetylcholinesterase 1 0.0327 0.4064 0.9169
Echinococcus granulosus orexin receptor type 2 0.0018 0.0031 0.0035
Brugia malayi hypothetical protein 0.0018 0.0031 0.0069
Brugia malayi sulfakinin receptor protein 0.0018 0.0031 0.0069
Mycobacterium ulcerans fusion of enoyl-CoA hydratase, EchA21 and lipase, LipE 0.0035 0.0254 0.0703
Echinococcus granulosus tm gpcr rhodopsin 0.0018 0.0031 0.0035
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0282 0.3477 1
Schistosoma mansoni carbonic anhydrase-related 0.0117 0.1323 0.156
Loa Loa (eye worm) G-protein coupled receptor 0.0018 0.0031 0.0069
Echinococcus granulosus hepatocyte nuclear factor 4 alpha 0.004 0.0323 0.0371
Loa Loa (eye worm) hypothetical protein 0.0023 0.01 0.0225
Loa Loa (eye worm) hypothetical protein 0.0048 0.0429 0.0967
Schistosoma mansoni nuclear hormone receptor superfamily protein-related 0.0019 0.0047 0.0056
Toxoplasma gondii hypothetical protein 0.0047 0.0408 0.3081
Brugia malayi AMP-binding enzyme family protein 0.0023 0.01 0.0225
Mycobacterium tuberculosis Probable fructose-bisphosphate aldolase Fba 0.0138 0.1597 0.4424
Entamoeba histolytica DNA repair and recombination protein RAD52, putative 0.0336 0.4174 1
Entamoeba histolytica serine/threonine protein kinase, putative 0.0091 0.099 0.2289
Echinococcus multilocularis biogenic amine (5HT) receptor 0.0018 0.0031 0.0031
Echinococcus multilocularis rhodopsin orphan GPCR 0.0018 0.0031 0.0031
Brugia malayi nuclear receptor RXR 0.0021 0.0077 0.0174
Toxoplasma gondii ABC1 family protein 0.0035 0.0254 0.1921
Plasmodium falciparum flap endonuclease 1 0.0025 0.0129 0.0974
Echinococcus granulosus ecdysone induced protein 78C 0.004 0.0323 0.0371
Brugia malayi Cell division protein ftsZ 0.0144 0.1681 0.3793
Loa Loa (eye worm) hypothetical protein 0.0029 0.0177 0.0399
Loa Loa (eye worm) hypothetical protein 0.0018 0.0031 0.0069
Brugia malayi Calcitonin receptor-like protein seb-1 0.0048 0.0429 0.0967
Toxoplasma gondii flap structure-specific endonuclease 1, putative 0.0025 0.0129 0.0974
Echinococcus multilocularis neuropeptide receptor A26 0.0462 0.5817 0.5817
Echinococcus granulosus Nuclear hormone receptor family member nhr 41 0.004 0.0323 0.0371
Loa Loa (eye worm) hypothetical protein 0.0018 0.0031 0.0069
Loa Loa (eye worm) hypothetical protein 0.0018 0.0031 0.0069
Echinococcus multilocularis alpha 1A adrenergic receptor 0.0018 0.0031 0.0031
Brugia malayi serine/threonine-protein kinase plk-2 0.0091 0.099 0.2233
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0282 0.3477 1
Brugia malayi Nuclear hormone receptor family member nhr-41 0.004 0.0323 0.0728
Trypanosoma cruzi hypothetical protein 0.0064 0.0637 0.1436
Echinococcus multilocularis g protein linked acetylcholine receptor gar 2a 0.0018 0.0031 0.0031
Loa Loa (eye worm) pigment dispersing factor receptor c 0.0048 0.0429 0.0967
Toxoplasma gondii histone lysine methyltransferase SET/SUV39 0.0029 0.0177 0.1336
Brugia malayi Eukaryotic-type carbonic anhydrase family protein 0.0117 0.1323 0.2985
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0044 0.0377 0.0433
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0282 0.3477 1
Loa Loa (eye worm) hypothetical protein 0.0018 0.0031 0.0069
Brugia malayi hypothetical protein 0.0018 0.0031 0.0069
Brugia malayi GTP-binding regulatory protein Gs alpha-S chain, putative 0.0044 0.0377 0.085
Brugia malayi G-protein coupled receptor 0.0018 0.0031 0.0069
Loa Loa (eye worm) melatonin receptor type 1A 0.0018 0.0031 0.0069
Schistosoma mansoni carbonic anhydrase 0.0117 0.1323 0.156
Brugia malayi RE15519p 0.0018 0.0031 0.0069
Brugia malayi ecdysone receptor 0.0019 0.0047 0.0107
Schistosoma mansoni myosin xvIII 0.0018 0.0031 0.0036
Echinococcus granulosus terminal deoxycytidyl transferase rev1 0.0019 0.0044 0.0051
Trichomonas vaginalis myo inositol monophosphatase, putative 0.0036 0.0266 0.0646
Brugia malayi larval opioid receptor 0.0018 0.0031 0.0069
Schistosoma mansoni peptide (FMRFamide/neurokinin-3)-like receptor 0.0018 0.0031 0.0036
Loa Loa (eye worm) hypothetical protein 0.0018 0.0031 0.0069
Trichomonas vaginalis Clan CE, family C48, Ulp1-like cysteine peptidase 0.0064 0.0637 0.1726
Echinococcus granulosus retinoic acid receptor rxr beta a 0.004 0.0323 0.0371
Brugia malayi G-protein coupled receptor 0.0018 0.0031 0.0069
Loa Loa (eye worm) hypothetical protein 0.0019 0.0047 0.0107
Loa Loa (eye worm) hypothetical protein 0.0018 0.0031 0.0069
Brugia malayi nuclear receptor NHR-67 0.0019 0.0047 0.0107
Brugia malayi Inositol-1 0.0036 0.0266 0.06
Loa Loa (eye worm) hypothetical protein 0.0018 0.0031 0.0069
Plasmodium vivax acyl-CoA synthetase, putative 0.0017 0.0024 0.0591
Echinococcus multilocularis Basic leucine zipper (bZIP) transcription 0.0035 0.0254 0.0254
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0044 0.0377 0.0444
Loa Loa (eye worm) beta-LACTamase domain containing family member 0.0035 0.0254 0.0574
Trypanosoma brucei polo-like protein kinase 0.0091 0.099 0.2232
Echinococcus multilocularis flap endonuclease 1 0.0025 0.0129 0.0129
Echinococcus multilocularis serine:threonine protein kinase PLK1 0.0091 0.099 0.099
Echinococcus multilocularis 7TM GPCR, rhodopsin 0.0018 0.0031 0.0031
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0044 0.0377 0.0377
Leishmania major cytochrome p450-like protein 0.0015 0.0001 0.0001
Mycobacterium leprae Probable fructose bisphosphate aldolase Fba 0.0138 0.1597 0.4266
Echinococcus multilocularis rhodopsin orphan GPCR 0.0018 0.0031 0.0031
Schistosoma mansoni ancient conserved domain protein 2 (cyclin m2) 0.0018 0.0031 0.0036
Loa Loa (eye worm) hypothetical protein 0.004 0.0323 0.0728
Schistosoma mansoni inositol monophosphatase 0.0036 0.0266 0.0314
Loa Loa (eye worm) cytochrome P450 family protein 0.0015 0.0001 0.0002
Loa Loa (eye worm) hypothetical protein 0.0035 0.0254 0.0574
Loa Loa (eye worm) hypothetical protein 0.0019 0.0047 0.0107
Loa Loa (eye worm) nuclear hormone receptor family member nhr-40 0.004 0.0323 0.0728
Brugia malayi nuclear receptor NHR-88 0.0019 0.0047 0.0107
Echinococcus multilocularis thyroid hormone receptor alpha 0.004 0.0323 0.0323
Loa Loa (eye worm) hypothetical protein 0.0018 0.0031 0.0069
Loa Loa (eye worm) hypothetical protein 0.0019 0.0047 0.0107
Brugia malayi nuclear hormone receptor family member odr-7 0.0019 0.0047 0.0107
Echinococcus granulosus rhodopsin orphan GPCR 0.0018 0.0031 0.0035
Onchocerca volvulus Bile acid receptor homolog 0.004 0.0323 0.1062
Schistosoma mansoni neuropeptide receptor 0.0018 0.0031 0.0036
Echinococcus multilocularis fmrfamide receptor 0.0018 0.0031 0.0031
Schistosoma mansoni alpha-1 adrenergic receptor 0.0018 0.0031 0.0036
Echinococcus granulosus g protein linked acetylcholine receptor gar 2a 0.0018 0.0031 0.0035
Trichomonas vaginalis glutaminase, putative 0.0265 0.3255 0.9353
Mycobacterium tuberculosis Conserved protein 0.0035 0.0254 0.0704
Brugia malayi ImpB/MucB/SamB family protein 0.0019 0.0044 0.01
Schistosoma mansoni FTZ-F1 nuclear receptor-like protein 0.004 0.0323 0.0381
Brugia malayi Iron-sulfur cluster assembly accessory protein 0.0047 0.0408 0.0921
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD5 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0016 0.0012 0.0033
Loa Loa (eye worm) hypothetical protein 0.0033 0.023 0.0519
Echinococcus multilocularis neuropeptide receptor 0.0018 0.0031 0.0031
Brugia malayi Carboxylesterase family protein 0.0055 0.0522 0.1177
Echinococcus granulosus p2X purinoceptor 4 0.0291 0.3585 0.4116
Trichomonas vaginalis Clan CE, family C48, Ulp1-like cysteine peptidase 0.0064 0.0637 0.1726
Echinococcus multilocularis conserved hypothetical protein 0.0667 0.848 0.848
Trypanosoma cruzi DNA polymerase eta, putative 0.0019 0.0044 0.0099
Echinococcus multilocularis Nuclear hormone receptor HR96 0.0019 0.0047 0.0047
Loa Loa (eye worm) hypothetical protein 0.0021 0.0077 0.0174
Entamoeba histolytica Rad52/22 family double-strand break repair protein, putative 0.0096 0.1046 0.2425
Loa Loa (eye worm) hypothetical protein 0.0018 0.0031 0.0069
Mycobacterium ulcerans glutaminase 0.0265 0.3255 0.9018
Schistosoma mansoni coup transcription factor 0.004 0.0323 0.0381
Schistosoma mansoni biogenic amine (octopamine/dopamine) receptor 0.0018 0.0031 0.0036
Schistosoma mansoni family S9 non-peptidase homologue (S09 family) 0.0055 0.0522 0.0615
Mycobacterium ulcerans long-chain-fatty-acid--CoA ligase 0.0023 0.01 0.0274
Echinococcus granulosus FTZ F1 alpha 0.004 0.0323 0.0371
Trichomonas vaginalis D-aminoacylase, putative 0.0035 0.0254 0.0612
Loa Loa (eye worm) hypothetical protein 0.0018 0.0031 0.0069
Loa Loa (eye worm) hypothetical protein 0.0018 0.0031 0.0069
Wolbachia endosymbiont of Brugia malayi cell division protein FtsZ 0.0293 0.361 1
Echinococcus granulosus neuropeptide receptor 0.0018 0.0031 0.0035
Loa Loa (eye worm) neuropeptide F receptor 0.0018 0.0031 0.0069
Loa Loa (eye worm) hypothetical protein 0.0055 0.0522 0.1177
Brugia malayi hypothetical protein 0.0055 0.0522 0.1177
Echinococcus granulosus thyrotropin releasing hormone receptor 0.0018 0.0031 0.0035
Loa Loa (eye worm) hypothetical protein 0.0018 0.0031 0.0069
Loa Loa (eye worm) hypothetical protein 0.0118 0.1342 0.3028
Loa Loa (eye worm) nuclear hormone receptor 0.0019 0.0047 0.0107
Mycobacterium ulcerans esterase/lipase LipP 0.0035 0.0254 0.0703
Brugia malayi isocitrate dehydrogenase 0.0015 0 0.0001
Schistosoma mansoni lamin 0.0026 0.0141 0.0166
Loa Loa (eye worm) carboxylesterase 0.0327 0.4064 0.9169
Brugia malayi Carboxylesterase family protein 0.0055 0.0522 0.1177
Loa Loa (eye worm) hypothetical protein 0.0035 0.0254 0.0574
Giardia lamblia Fructose-bisphosphate aldolase 0.0282 0.3477 0.8314
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0018 0.0031 0.0036
Schistosoma mansoni nuclear hormone receptor 0.0019 0.0047 0.0056
Brugia malayi nuclear receptor subfamily 1, group D, member 1, putative 0.0019 0.0047 0.0107
Plasmodium falciparum SUMO-activating enzyme subunit 1 0.0047 0.0408 0.3081
Loa Loa (eye worm) hypothetical protein 0.0067 0.0676 0.1526
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0018 0.0031 0.0031
Echinococcus granulosus g protein coupled receptor 0.0018 0.0031 0.0035
Echinococcus multilocularis lamin dm0 0.0026 0.0141 0.0141
Schistosoma mansoni intermediate filament proteins 0.0026 0.0141 0.0166
Schistosoma mansoni glutaminase 0.0265 0.3255 0.3839
Trypanosoma cruzi DNA polymerase kappa, putative 0.0019 0.0044 0.0099
Loa Loa (eye worm) hypothetical protein 0.0019 0.0047 0.0107
Loa Loa (eye worm) hypothetical protein 0.0023 0.01 0.0225
Echinococcus granulosus rhodopsin orphan GPCR 0.0018 0.0031 0.0035
Echinococcus granulosus G protein coupled receptor 139 0.0018 0.0031 0.0035
Echinococcus multilocularis neuropeptide Y receptor 0.0018 0.0031 0.0031
Trichomonas vaginalis CAMK family protein kinase 0.0091 0.099 0.2753
Onchocerca volvulus Huntingtin homolog 0.0118 0.1342 0.477
Trichomonas vaginalis inositol monophosphatase, putative 0.0036 0.0266 0.0646
Loa Loa (eye worm) hypothetical protein 0.0018 0.0031 0.0069
Mycobacterium tuberculosis Possible conserved lipoprotein LpqK 0.0035 0.0254 0.0704
Mycobacterium tuberculosis Conserved hypothetical protein 0.0019 0.0044 0.0122
Entamoeba histolytica hypothetical protein 0.0035 0.0254 0.0508
Mycobacterium ulcerans DNA polymerase IV 0.0019 0.0044 0.0121
Echinococcus multilocularis lamin 0.0026 0.0141 0.0141
Schistosoma mansoni RAR-like nuclear receptor 0.004 0.0323 0.0381
Schistosoma mansoni nuclear hormone receptor 0.0019 0.0047 0.0056
Mycobacterium tuberculosis Probable chain -fatty-acid-CoA ligase FadD13 (fatty-acyl-CoA synthetase) 0.0023 0.01 0.0276
Toxoplasma gondii inositol(myo)-1(or 4)-monophosphatase 2, putative 0.0036 0.0266 0.201
Loa Loa (eye worm) hypothetical protein 0.0018 0.0031 0.0069
Echinococcus granulosus neuropeptide s receptor 0.0462 0.5817 0.6678
Mycobacterium ulcerans hypothetical protein 0.0035 0.0254 0.0703
Schistosoma mansoni hepatocyte nuclear factor 4-alpha (hnf-4-alpha) 0.0019 0.0047 0.0056
Loa Loa (eye worm) hypothetical protein 0.0144 0.168 0.3791
Echinococcus multilocularis rhodopsin orphan GPCR 0.0018 0.0031 0.0031
Mycobacterium ulcerans beta-lactamase 0.0035 0.0254 0.0703
Trichomonas vaginalis Clan CE, family C48, Ulp1-like cysteine peptidase 0.0064 0.0637 0.1726
Echinococcus granulosus tumor susceptibility gene 101 protein 0.0067 0.0676 0.0776
Loa Loa (eye worm) hypothetical protein 0.0018 0.0031 0.0069
Giardia lamblia Kinase, PLK 0.0091 0.099 0.2289
Loa Loa (eye worm) intermediate filament tail domain-containing protein 0.0026 0.0141 0.0318
Schistosoma mansoni retinoid-x-receptor (RXR) 0.004 0.0323 0.0381
Mycobacterium tuberculosis POSSIBLE PARA-NITROBENZYL ESTERASE (FRAGMENT) 0.0055 0.0522 0.1445
Loa Loa (eye worm) hypothetical protein 0.0018 0.0031 0.0069
Brugia malayi nuclear hormone receptor 0.004 0.0323 0.0728
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0044 0.0377 0.0444
Brugia malayi Putative carbonic anhydrase 5 precursor 0.0216 0.2611 0.5891
Mycobacterium ulcerans fructose-bisphosphate aldolase 0.0138 0.1597 0.4423
Mycobacterium tuberculosis Probable lipase LipE 0.0035 0.0254 0.0704
Echinococcus granulosus p2X purinoceptor 4 0.0291 0.3585 0.4116
Echinococcus granulosus neuropeptides capa receptor 0.0018 0.0031 0.0035
Schistosoma mansoni kinase 0.0046 0.0405 0.0478
Entamoeba histolytica fructose-1,6-bisphosphate aldolase, putative 0.0282 0.3477 0.8314
Echinococcus multilocularis neuropeptide receptor 0.0018 0.0031 0.0031
Loa Loa (eye worm) hypothetical protein 0.0017 0.0024 0.0055
Brugia malayi Nuclear hormone receptor family member nhr-49 0.004 0.0323 0.0728
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD7 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0016 0.0012 0.0033
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.004 0.0323 0.0323
Onchocerca volvulus Serine\/threonine kinase homolog 0.0091 0.099 0.3487
Loa Loa (eye worm) intermediate filament protein 0.0026 0.0141 0.0318
Brugia malayi ERG2 and Sigma1 receptor like protein 0.0356 0.4433 1
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0018 0.0031 0.0036
Echinococcus multilocularis retinoic acid receptor rxr beta a retinoic acid receptor rxr alpha a retinoic acid receptor rxr alpha 0.0019 0.0047 0.0047
Loa Loa (eye worm) hypothetical protein 0.0018 0.0031 0.0069
Loa Loa (eye worm) hypothetical protein 0.004 0.0323 0.0728
Brugia malayi AMP-binding enzyme family protein 0.0023 0.01 0.0225
Plasmodium falciparum ataxin-2 like protein, putative 0.0024 0.012 0.0905
Loa Loa (eye worm) eukaryotic-type carbonic anhydrase 0.0117 0.1323 0.2985
Loa Loa (eye worm) isocitrate dehydrogenase 0.0015 0 0.0001
Loa Loa (eye worm) nuclear hormone receptor family member nhr-14 0.004 0.0323 0.0728
Schistosoma mansoni rab geranylgeranyl transferase alpha subunit 0.0019 0.0044 0.0052
Schistosoma mansoni hypothetical protein 0.0018 0.0031 0.0036
Schistosoma mansoni muscarinic acetylcholine (GAR) receptor 0.0018 0.0031 0.0036
Echinococcus multilocularis p2X purinoceptor 4 0.0291 0.3585 0.3585
Mycobacterium ulcerans long-chain fatty-acid CoA ligase 0.0023 0.01 0.0274
Mycobacterium ulcerans extragenic suppressor protein SuhB 0.0036 0.0266 0.0735
Echinococcus granulosus neuropeptides capa receptor 0.0018 0.0031 0.0035
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0044 0.0377 0.0377
Leishmania major hypothetical protein, conserved 0.0021 0.0081 0.0183
Schistosoma mansoni family S9 non-peptidase homologue (S09 family) 0.0327 0.4064 0.4792
Brugia malayi beta-lactamase family protein 0.0035 0.0254 0.0574
Loa Loa (eye worm) hypothetical protein 0.0035 0.0254 0.0574
Loa Loa (eye worm) hypothetical protein 0.0018 0.0031 0.0069
Brugia malayi ThiF family protein 0.0047 0.0408 0.092
Chlamydia trachomatis acylglycerophosphoethanolamine acyltransferase 0.0017 0.0024 0.5
Trypanosoma cruzi hypothetical protein, conserved 0.0035 0.0254 0.0573
Schistosoma mansoni Tr4/Tr2 (homologue) 0.004 0.0323 0.0381
Brugia malayi Nuclear hormone receptor-like 1 0.004 0.0323 0.0728
Echinococcus multilocularis sentrin specific protease 8 0.0064 0.0637 0.0637
Trypanosoma cruzi cytochrome P450, putative 0.0015 0.0001 0.0001
Brugia malayi G protein-coupled receptor 0.0018 0.0031 0.0069
Onchocerca volvulus 0.0029 0.0177 0.0532
Echinococcus multilocularis BC026374 protein (S09 family) 0.0055 0.0522 0.0522
Echinococcus granulosus nuclear receptor subfamily 1 group D 0.0021 0.0077 0.0088
Trichomonas vaginalis CAMK family protein kinase 0.0091 0.099 0.2753
Echinococcus granulosus 7TM GPCR rhodopsin 0.0018 0.0031 0.0035
Mycobacterium ulcerans carboxylesterase, LipT 0.0055 0.0522 0.1444
Echinococcus multilocularis dna polymerase eta 0.0019 0.0044 0.0044
Brugia malayi Steroid receptor seven-up type 2 0.004 0.0323 0.0728
Echinococcus multilocularis hepatocyte nuclear factor 4 alpha 0.004 0.0323 0.0323
Brugia malayi Dopamine receptor 0.0018 0.0031 0.0069
Schistosoma mansoni neuropeptide receptor 0.0018 0.0031 0.0036
Trypanosoma brucei cytochrome P450, putative 0.0015 0.0001 0.0001
Mycobacterium ulcerans fatty-acid-CoA ligase 0.0023 0.01 0.0274
Mycobacterium tuberculosis Probable esterase LipL 0.0035 0.0254 0.0704
Echinococcus granulosus somatostatin receptor 0.0018 0.0031 0.0035
Schistosoma mansoni nuclear receptor nhr-48 0.0019 0.0047 0.0056
Echinococcus granulosus SUMO activating enzyme subunit 1 0.0047 0.0408 0.0468
Loa Loa (eye worm) glutaminase 0.0265 0.3255 0.7344
Plasmodium falciparum acyl-CoA synthetase 0.0017 0.0024 0.0182
Brugia malayi Nuclear hormone receptor-like 1 0.0021 0.0077 0.0174
Loa Loa (eye worm) hypothetical protein 0.0017 0.0024 0.0055
Leishmania major hypothetical protein, conserved 0.0024 0.012 0.027
Echinococcus granulosus allatostatin A receptor 0.0018 0.0031 0.0035
Loa Loa (eye worm) hypothetical protein 0.0117 0.1323 0.2985
Schistosoma mansoni serine/threonine protein kinase 0.0091 0.099 0.1167
Onchocerca volvulus 0.0023 0.01 0.0251
Echinococcus granulosus acetylcholinesterase 0.0327 0.4064 0.4666
Echinococcus granulosus biogenic amine 5HT receptor 0.0018 0.0031 0.0035
Echinococcus multilocularis sex peptide receptor 0.0018 0.0031 0.0031
Trypanosoma brucei DNA polymerase kappa, putative 0.0019 0.0044 0.0099
Loa Loa (eye worm) hypothetical protein 0.0018 0.0031 0.0069
Brugia malayi Nuclear hormone receptor family member nhr-25 0.004 0.0323 0.0728
Loa Loa (eye worm) hypothetical protein 0.0018 0.0031 0.0069
Mycobacterium tuberculosis Probable conserved lipoprotein 0.0035 0.0254 0.0704
Loa Loa (eye worm) ThiF family protein 0.0031 0.0201 0.0452
Mycobacterium ulcerans acyl-CoA synthetase 0.0023 0.01 0.0274
Mycobacterium ulcerans DNA polymerase IV 0.0019 0.0044 0.0121
Echinococcus granulosus histone lysine methyltransferase setb 0.0029 0.0177 0.0203
Toxoplasma gondii LsmAD domain-containing protein 0.0024 0.012 0.0905
Loa Loa (eye worm) hypothetical protein 0.0055 0.0522 0.1177
Brugia malayi Carboxylesterase family protein 0.0327 0.4064 0.9169
Schistosoma mansoni opsin-like receptor 0.0018 0.0031 0.0036
Echinococcus multilocularis serotonin receptor 0.0018 0.0031 0.0031
Loa Loa (eye worm) hypothetical protein 0.0021 0.0077 0.0174
Brugia malayi hypothetical protein 0.0018 0.0031 0.0069
Trypanosoma cruzi DNA polymerase kappa, putative 0.0019 0.0044 0.0099
Brugia malayi hypothetical protein 0.0018 0.0031 0.0069
Leishmania major protein kinase, putative,polo-like protein kinase, putative 0.0091 0.099 0.2232
Echinococcus multilocularis terminal deoxycytidyl transferase rev1 0.0019 0.0044 0.0044
Loa Loa (eye worm) neuropeptide F receptor 0.0018 0.0031 0.0069
Schistosoma mansoni nuclear hormone receptor 0.004 0.0323 0.0381
Loa Loa (eye worm) hypothetical protein 0.0047 0.0408 0.092
Schistosoma mansoni neuropeptide f receptor 76f 0.0018 0.0031 0.0036
Loa Loa (eye worm) hypothetical protein 0.0018 0.0031 0.0069
Trypanosoma brucei flap endonuclease-1 (FEN-1), putative 0.0025 0.0129 0.0291
Brugia malayi Nuclear hormone receptor family member nhr-25 0.004 0.0323 0.0728
Schistosoma mansoni gliotactin 0.0055 0.0522 0.0615
Loa Loa (eye worm) nuclear receptor NHR-67 0.0019 0.0047 0.0107
Schistosoma mansoni peptide (allatostatin/somatostatin)-like receptor 0.0018 0.0031 0.0036
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.004 0.0323 0.0728
Brugia malayi Dopamine receptor protein 1, putative (partial) 0.0018 0.0031 0.0069
Giardia lamblia Flap structure-specific endonuclease 0.0025 0.0129 0.0205
Trichomonas vaginalis set domain proteins, putative 0.0229 0.2781 0.7971
Loa Loa (eye worm) hypothetical protein 0.004 0.0323 0.0728
Schistosoma mansoni amine GPCR 0.0018 0.0031 0.0036
Schistosoma mansoni histamine-responsive GPCR (AAF21638) 0.0018 0.0031 0.0036
Echinococcus granulosus tachykinin peptides receptor 99D 0.0018 0.0031 0.0035
Loa Loa (eye worm) hypothetical protein 0.0019 0.0047 0.0107
Trypanosoma brucei DNA polymerase kappa, putative 0.0019 0.0044 0.0099
Brugia malayi Cytochrome P450 family protein 0.0015 0.0001 0.0002
Trypanosoma cruzi PAB1-binding protein , putative 0.0024 0.012 0.027
Brugia malayi Carboxylesterase family protein 0.0055 0.0522 0.1177
Echinococcus granulosus Nuclear hormone receptor HR96 0.0019 0.0047 0.0054
Trypanosoma brucei inositol-1(or 4)-monophosphatase 1, putative 0.0036 0.0266 0.06
Brugia malayi hypothetical protein 0.0018 0.0031 0.0069
Schistosoma mansoni tsg101-related 0.0056 0.053 0.0625
Schistosoma mansoni BC026374 protein (S09 family) 0.0055 0.0522 0.0615
Loa Loa (eye worm) carboxylesterase 0.0055 0.0522 0.1177
Onchocerca volvulus 0.0035 0.0254 0.0813
Onchocerca volvulus 0.0055 0.0522 0.1786
Loa Loa (eye worm) hypothetical protein 0.0228 0.2776 0.6262
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0018 0.0031 0.0036
Trypanosoma cruzi polo-like protein kinase, putative 0.0091 0.099 0.2232
Echinococcus granulosus serotonin receptor 0.0018 0.0031 0.0035
Trypanosoma brucei PAB1-binding protein , putative 0.0024 0.012 0.027
Leishmania major flap endonuclease-1 (FEN-1), putative 0.0025 0.0129 0.0291
Loa Loa (eye worm) hypothetical protein 0.0035 0.0254 0.0574
Trypanosoma cruzi carbonic anhydrase-like protein, putative 0.0216 0.2611 0.589
Entamoeba histolytica hypothetical protein 0.0035 0.0254 0.0508
Echinococcus multilocularis FTZ F1 nuclear receptor protein 0.004 0.0323 0.0323
Echinococcus multilocularis carbonic anhydrase 0.0117 0.1323 0.1323
Mycobacterium tuberculosis Cell division protein FtsZ 0.0293 0.361 1
Schistosoma mansoni P2X receptor subunit 0.0291 0.3585 0.4227
Schistosoma mansoni sumo-1-activating enzyme E1a 0.0042 0.0352 0.0415
Echinococcus granulosus carbonic anhydrase 0.0117 0.1323 0.1519
Echinococcus granulosus acetylcholinesterase 0.0327 0.4064 0.4666
Schistosoma mansoni thyrotropin-releasing hormone receptor 0.0018 0.0031 0.0036
Loa Loa (eye worm) nuclear Hormone Receptor family member 0.004 0.0323 0.0728
Entamoeba histolytica hypothetical protein 0.0035 0.0254 0.0508
Schistosoma mansoni carbonic anhydrase-related 0.0117 0.1323 0.156
Echinococcus multilocularis g protein coupled receptor 0.0018 0.0031 0.0031
Brugia malayi conserved hypotetical protein 0.0019 0.0047 0.0107
Entamoeba histolytica hypothetical protein 0.0096 0.1046 0.2425
Echinococcus granulosus FTZ F1 nuclear receptor protein 0.004 0.0323 0.0371
Echinococcus multilocularis pyroglutamylated rfamide peptide receptor 0.0018 0.0031 0.0031
Loa Loa (eye worm) hypothetical protein 0.0024 0.012 0.0271
Onchocerca volvulus 0.0026 0.0141 0.04
Onchocerca volvulus Steroid hormone receptor family member cnr14 homolog 0.004 0.0323 0.1062
Echinococcus granulosus carbonic anhydrase 0.0117 0.1323 0.1519
Brugia malayi Muscleblind-like protein 0.0144 0.168 0.3791
Leishmania major myo-inositol-1(or 4)-monophosphatase 1, putative 0.0036 0.0266 0.06
Loa Loa (eye worm) hypothetical protein 0.0018 0.0031 0.0069
Loa Loa (eye worm) hypothetical protein 0.0018 0.0031 0.0069
Echinococcus granulosus COUP TF:Svp nuclear hormone receptor 0.004 0.0323 0.0371
Echinococcus multilocularis tumor susceptibility gene 101 protein 0.0067 0.0676 0.0676
Schistosoma mansoni hypothetical protein 0.0018 0.0031 0.0036
Echinococcus multilocularis para nitrobenzyl esterase 0.0055 0.0522 0.0522
Onchocerca volvulus Nuclear receptor subfamily 6 group A member 1 homolog 0.0019 0.0047 0.0061
Echinococcus multilocularis neuropeptide FF receptor 2 0.0018 0.0031 0.0031
Loa Loa (eye worm) hypothetical protein 0.0327 0.4064 0.9169
Loa Loa (eye worm) hypothetical protein 0.0018 0.0031 0.0069
Brugia malayi intermediate filament protein 0.0026 0.0141 0.0318
Trichomonas vaginalis CAMK family protein kinase 0.0045 0.039 0.1006
Schistosoma mansoni amine GPCR 0.0018 0.0031 0.0036
Brugia malayi ThiF family protein 0.0031 0.0201 0.0452
Trichomonas vaginalis CAMK family protein kinase 0.0091 0.099 0.2753
Echinococcus granulosus rhodopsin orphan GPCR 0.0018 0.0031 0.0035
Schistosoma mansoni tsg101-related 0.0046 0.0397 0.0468
Echinococcus granulosus para nitrobenzyl esterase 0.0055 0.0522 0.0599
Schistosoma mansoni neuropeptide F-like receptor 0.0018 0.0031 0.0036
Schistosoma mansoni inositol monophosphatase 0.0036 0.0266 0.0314
Brugia malayi nuclear hormone receptor 0.0019 0.0047 0.0107
Trypanosoma cruzi ubiquitin-activating enzyme, putative 0.0031 0.0201 0.0452
Trichomonas vaginalis myo inositol monophosphatase, putative 0.0036 0.0266 0.0646
Schistosoma mansoni P2X receptor subunit 0.0291 0.3585 0.4227
Brugia malayi Nuclear hormone receptor family member nhr-19 0.004 0.0323 0.0728
Echinococcus multilocularis p2X purinoceptor 4 0.0291 0.3585 0.3585
Trichomonas vaginalis CAMK family protein kinase 0.0091 0.099 0.2753
Brugia malayi Hypothetical 52.5 kDa protein ZK945.1 in chromosome II, putative 0.0035 0.0254 0.0574
Loa Loa (eye worm) hypothetical protein 0.0018 0.0031 0.0069
Echinococcus multilocularis COUP TF:Svp nuclear hormone receptor 0.004 0.0323 0.0323
Loa Loa (eye worm) hypothetical protein 0.0017 0.0024 0.0055
Echinococcus multilocularis musashi 0.0026 0.0141 0.0141
Trypanosoma brucei Vps23 core domain containing protein, putative 0.0021 0.0081 0.0183
Loa Loa (eye worm) hypothetical protein 0.0026 0.0135 0.0304
Onchocerca volvulus Huntingtin homolog 0.0118 0.1342 0.477
Echinococcus granulosus 7tm_1 domain containing protein 0.0018 0.0031 0.0035
Brugia malayi Nuclear hormone receptor E75 0.0019 0.0047 0.0107
Trichomonas vaginalis D-aminoacylase, putative 0.0035 0.0254 0.0612
Trichomonas vaginalis CAMK family protein kinase 0.0091 0.099 0.2753
Brugia malayi putative neuropeptide receptor NPR1 0.0018 0.0031 0.0069
Echinococcus multilocularis nuclear receptor subfamily 1 group D 0.0021 0.0077 0.0077
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0018 0.0031 0.0031
Mycobacterium tuberculosis Carboxylesterase LipT 0.0055 0.0522 0.1445
Loa Loa (eye worm) hypothetical protein 0.0055 0.0522 0.1177
Mycobacterium ulcerans hypothetical protein 0.0023 0.01 0.0274
Schistosoma mansoni neuropeptide receptor 0.0018 0.0031 0.0036
Brugia malayi hypothetical protein 0.0024 0.012 0.0271
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD2 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0023 0.01 0.0276
Echinococcus granulosus sentrin specific protease 8 0.0064 0.0637 0.0731
Schistosoma mansoni amine GPCR 0.0018 0.0031 0.0036
Mycobacterium tuberculosis Conserved protein 0.0035 0.0254 0.0704
Echinococcus granulosus sex peptide receptor 0.0018 0.0031 0.0035
Loa Loa (eye worm) hypothetical protein 0.0018 0.0031 0.0069
Echinococcus granulosus nuclear receptor 2DBD gamma 0.004 0.0323 0.0371
Loa Loa (eye worm) steroid hormone receptor 0.004 0.0323 0.0728
Schistosoma mansoni amine GPCR 0.0018 0.0031 0.0036
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0282 0.3477 1
Echinococcus granulosus dro:myosuppressin receptor 0.0018 0.0031 0.0035
Brugia malayi AMP-binding enzyme family protein 0.0023 0.01 0.0225
Mycobacterium ulcerans cell division protein FtsZ 0.0293 0.361 1
Echinococcus multilocularis SUMO activating enzyme subunit 2 0.0031 0.0201 0.0201
Brugia malayi GnHR receptor homolog 0.0018 0.0031 0.0069
Loa Loa (eye worm) hypothetical protein 0.0019 0.0047 0.0107
Brugia malayi Dopamine receptor protein 2 0.0018 0.0031 0.0069
Echinococcus multilocularis somatostatin receptor 0.0018 0.0031 0.0031
Loa Loa (eye worm) ImpB/MucB/SamB family protein 0.0019 0.0044 0.01
Loa Loa (eye worm) hypothetical protein 0.0019 0.0047 0.0107
Echinococcus granulosus microtubule associated protein 2 0.0667 0.848 0.9737
Schistosoma mansoni transcription factor LCR-F1 0.0035 0.0254 0.03
Trypanosoma cruzi DNA polymerase kappa, putative 0.0019 0.0044 0.0099
Brugia malayi Serotonin receptor 0.0018 0.0031 0.0069
Echinococcus multilocularis serotonin receptor 0.0018 0.0031 0.0031
Toxoplasma gondii ThiF family protein 0.0031 0.0201 0.1514
Loa Loa (eye worm) nuclear hormone receptor-like 1 0.0021 0.0077 0.0174
Echinococcus granulosus g protein coupled receptor 0.0018 0.0031 0.0035
Brugia malayi Nuclear hormone receptor family member nhr-31 0.004 0.0323 0.0728
Brugia malayi Dopamine receptor protein 1 0.0018 0.0031 0.0069
Brugia malayi hypothetical protein 0.0018 0.0031 0.0069
Echinococcus granulosus neuropeptide receptor A26 0.0462 0.5817 0.6678
Brugia malayi glutaminase DH11.1 0.0265 0.3255 0.7344
Echinococcus granulosus intermediate filament protein 0.0026 0.0141 0.0162
Trichomonas vaginalis D-aminoacylase, putative 0.0035 0.0254 0.0612
Brugia malayi Nuclear hormone receptor family member nhr-19 0.004 0.0323 0.0728
Schistosoma mansoni biogenic amine (5HT) receptor 0.0018 0.0031 0.0036
Schistosoma mansoni tsg101-related 0.0056 0.053 0.0625
Loa Loa (eye worm) hypothetical protein 0.0019 0.0044 0.01
Onchocerca volvulus 0.0019 0.0047 0.0061
Echinococcus granulosus thyroid hormone receptor alpha 0.0019 0.0047 0.0054
Leishmania major hypothetical protein, conserved 0.0035 0.0254 0.0573
Echinococcus granulosus fmrfamide receptor 0.0018 0.0031 0.0035
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0282 0.3477 1
Echinococcus multilocularis nuclear receptor subfamily 4 group A 0.0019 0.0047 0.0047
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0018 0.0031 0.0036
Brugia malayi beta-lactamase family protein 0.0035 0.0254 0.0574
Schistosoma mansoni biogenic amine receptor 0.0018 0.0031 0.0036
Echinococcus multilocularis g protein linked acetylcholine receptor gar 2a 0.0018 0.0031 0.0031
Onchocerca volvulus 0.0055 0.0522 0.1786
Echinococcus multilocularis neuropeptide Y receptor 0.0018 0.0031 0.0031
Echinococcus granulosus rhodopsin orphan GPCR 0.0018 0.0031 0.0035
Brugia malayi Tachykinin-like peptides receptor 99D 0.0018 0.0031 0.0069
Echinococcus multilocularis fmrfamide receptor 0.0018 0.0031 0.0031
Trichomonas vaginalis CAMK family protein kinase 0.0091 0.099 0.2753
Brugia malayi Nuclear hormone receptor family member nhr-14 0.004 0.0323 0.0728
Echinococcus granulosus growth hormone secretagogue receptor type 1 0.0018 0.0031 0.0035
Onchocerca volvulus 0.0035 0.0254 0.0813
Loa Loa (eye worm) hypothetical protein 0.0019 0.0047 0.0107
Schistosoma mansoni zinc finger protein 0.0019 0.0047 0.0056
Trypanosoma brucei DNA polymerase kappa, putative 0.0019 0.0044 0.0099
Schistosoma mansoni family S9 non-peptidase homologue (S09 family) 0.0055 0.0522 0.0615
Plasmodium falciparum SUMO-activating enzyme subunit 2 0.0031 0.0201 0.1514
Brugia malayi Isocitrate dehydrogenase 0.0015 0 0.0001
Entamoeba histolytica acyl-CoA synthetase, putative 0.0023 0.01 0.0134
Loa Loa (eye worm) hypothetical protein 0.0327 0.4064 0.9169
Echinococcus granulosus dna polymerase kappa 0.0019 0.0044 0.0051
Trichomonas vaginalis hypothetical protein 0.0033 0.0228 0.0534
Loa Loa (eye worm) hypothetical protein 0.0019 0.0047 0.0107
Leishmania major 4-coumarate:coa ligase-like protein 0.0023 0.01 0.0224
Schistosoma mansoni DNA polymerase eta 0.0019 0.0044 0.0052
Loa Loa (eye worm) hypothetical protein 0.0021 0.0077 0.0174
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0282 0.3477 1
Echinococcus granulosus Basic leucine zipper bZIP transcription 0.0035 0.0254 0.0292

Activities

Activity type Activity value Assay description Source Reference
Inhibition (binding) = -2 % Inhibition of Plasmodium falciparum FcB1 M1 aminopeptidase at 10 uM ChEMBL. 17326615
Inhibition (binding) = -2 % Inhibition of Plasmodium falciparum FcB1 M1 aminopeptidase at 10 uM ChEMBL. 17326615
Inhibition (binding) = 12 % Inhibition of pig kidney microsomal APN at 10 uM ChEMBL. 17326615
Inhibition (binding) = 12 % Inhibition of pig kidney microsomal APN at 10 uM ChEMBL. 17326615

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
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External resources for this compound

Bibliographic References

1 literature reference was collected for this gene.

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