Activity type | Activity value | Assay description | Source | Reference |
---|---|---|---|---|
IC50 (binding) | > 100 uM | Activity at human alpha1GlyR expressed in HEK293 cells by FMP assay | ChEMBL. | 17352465 |
IC50 (binding) | > 100 uM | Activity at human alpha1betaGlyR expressed in HEK293 cells by FMP assay | ChEMBL. | 17352465 |
IC50 (binding) | > 100 uM | Activity at human alpha2GlyR expressed in HEK293 cells by FMP assay | ChEMBL. | 17352465 |
IC50 (binding) | > 100 uM | Activity at human alpha1GlyR expressed in HEK293 cells by FMP assay | ChEMBL. | 17352465 |
IC50 (binding) | > 100 uM | Activity at human alpha1betaGlyR expressed in HEK293 cells by FMP assay | ChEMBL. | 17352465 |
IC50 (binding) | > 100 uM | Activity at human alpha2GlyR expressed in HEK293 cells by FMP assay | ChEMBL. | 17352465 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.
1 literature reference was collected for this gene.